Campus & Community
Harvard awards 9,434 degrees
Graduates celebrate as their School is announced in Tercentenary Theatre.Photo by Grace DuVal
May 30, 2025
3 min read
Totals reflect the 2024-25 academic year
Part of the
Commencement 2025
series
A collection of features and profiles covering Harvard University’s 374th Commencement.
On Thursday
A collection of features and profiles covering Harvard University’s 374th Commencement.
On Thursday the University awarded a total of 9,434 degrees. A breakdown of degrees and programs is listed below.
Harvard College granted a total of 2,014 degrees. Degrees from the Harvard John A. Paulson School of Engineering and Applied Sciences were awarded by Harvard College, the Kenneth C. Griffin Graduate School of Arts and Sciences, and the Graduate School of Design.
All Ph.D. degrees are conferred by the Kenneth C. Griffin Graduate School of Arts and Sciences.
All figures include degrees awarded in November 2024 and March and May 2025.
Harvard College 2,014 degrees
1,947 Bachelor of Arts
67 Bachelor of Science
Harvard Kenneth C. Griffin Graduate School of Arts and Sciences 1,357 degrees
395 Master of Arts
275 Master of Science
7 Master of Engineering
680 Doctor of Philosophy
Harvard John A. Paulson School of Engineering and Applied Sciences 881 degrees
446 Bachelor of Arts (conferred by Harvard College)
67 Bachelor of Science (conferred by Harvard College)
7 Master of Engineering (conferred by GSAS)
26 Master in Design Engineering (conferred jointly with GSD)
79 Doctor of Philosophy (conferred by GSAS)
Harvard Business School 944 degrees
802 Master in Business Administration
78 Master in Business Administration with Distinction
49 Master in Business Administration with High Distinction
15 Doctor of Philosophy (conferred by GSAS)
Harvard Divinity School 140 degrees
50 Master of Divinity
79 Master of Theological Studies
10 Master of Religion and Public Life
1 Doctor of Theology
Harvard Law School 784 degrees
177 Master of Laws
602 Doctor of Law
5 Doctor of Juridical Science
Harvard Kennedy School 618 degrees
78 Master in Public Administration
249 Master in Public Administration (Mid-Career)
73 Master in Public Administration in International Development
206 Master in Public Policy
1 Ph.D. in Political Economy and Government (conferred by GSAS)
11 Ph.D. in Public Policy (conferred by GSAS)
Harvard Graduate School of Design 393 degrees
126 Master of Architecture
24 Master of Architecture in Urban Design
65 Master in Design Studies
55 Master in Landscape Architecture
3 Master of Landscape Architecture in Urban Design
45 Master in Urban Planning
14 Doctor of Design
26 Master in Design Engineering (conferred jointly with SEAS)
35 Master in Real Estate
Harvard Graduate School of Education 766 degrees
720 Master of Education
25 Doctor of Education Leadership
21 Doctor of Education/Philosophy
Harvard Medical School 484 degrees
82 Master in Medical Science
166 Doctor of Medical Sciences
236 Doctor of Dental Medicine
Harvard School of Dental Medicine 66 degrees
17 Master of Medical Sciences
12 Doctor of Medical Sciences
37 Doctor of Dental Medicine
Harvard T.H. Chan School of Public Health 561 degrees
374 Master of Public Health
155 Master of Science
18 Master in Health Care Management
14 Doctor of Public Health
Harvard Extension School 1,360 degrees
133 Bachelor of Liberal Arts in Extension Studies
1,227 Masters of Liberal Arts in Extension Studies
Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
No joke: He’s graduating
With family in mind — and big dreams for the future — Harvard employee Jorge Mendoza completes long journey to degree
Nikki Rojas
Harvard Staff Writer
May 30, 2025
4 min read
Part of the
Commencement 2025
series
A collection of features and profiles
A collection of features and profiles covering Harvard University’s 374th Commencement.
Jorge Mendoza thought he was only joking when he told his then-girlfriend, now-wife, “Maybe one day I’ll go to school at Harvard.”
Years later, the joke, he’s happy to report, is on him.
“It actually came true!” says Mendoza, who graduated this week with a Bachelor’s in Liberal Arts in Extension Studies with a concentration on business administration and management.
Born in Colombia and raised in New York City, Mendoza joined Harvard as a custodial supervisor in 2018. Soon after, he enrolled at Harvard Extension School to pick up where prior college studies left off.
“To see the finish line, it’s unbelievable because it seemed so far,” said Mendoza, a 39-year-old father of two. “I’ve been in management for a very long time, so being able to do my business degree and knowing that this is what I want to do careerwise, it just made sense for me.”
“Jorge was one of those students who just came in and I saw determination to leave no stone unturned.”
Jill Slye
The six-year journey was far from easy. With help from Harvard’s Tuition Assistance Program, Mendoza immediately began to “chip away” at coursework, taking two courses per semester and a few over several summers. Two offerings on public speaking taught by Jill Slye were among his favorites.
Slye, in turn, praised Mendoza for his academic efforts.
“There are always students who tend to give off an energy that they are fully committed, right from the get-go,” she said. “They come into the class dedicated, open-minded, and nothing’s going to get in their way of learning. Jorge was one of those students who just came in and I saw determination to leave no stone unturned.”
Being a full-time employee and part-time student at Harvard offered Mendoza “insider knowledge” in his classes, he said. This spring Mendoza took an architecture class that incorporated a large number of buildings on campus, many of them familiar from his 9-to-5.
“Other people are joining the class from around the world,” he said. “They might be able to see pictures online and take some virtual tours. But to be able to be on campus, walk through or by the buildings, and even manage some of them gives you a unique [perspective],” he said.
Mendoza briefly considered skipping Commencement because it’s typically just another day on the job. “Then I really started getting excited about it.”
The only downside to being an employee who also takes classes is that you might not fully register the joy of being a Harvard student, Mendoza said. In fact, he briefly considered skipping Commencement because it’s typically just another day on the job.
But his mother and sisters told him that they wanted to be a part of the tradition, and his wife challenged his lack of enthusiasm. “Then I really started getting excited about it, and I said, ‘You know what? This is different. This is my Commencement. This is what I’ve worked so hard for,’” he said.
He’s also worked hard to serve as a role model to his kids.
“I want them to be able to say, ‘My dad finished while we were here,’” he said. “’He did it with kids and a family.”’
And that’s one big reason he’s not done yet. Mendoza has his eyes on a new goal: a master’s in liberal arts in sustainability from the Extension School.
“I hope to continue to grow academically, because I love to learn,” he said. “I want to go back to focus on sustainability. It’s a focus of the University and of the world. It is something I want to focus on to grow and develop in my career and to continue to make an impact.”
Photos by Niles Singer and Veasey Conway/Harvard Staff Photographers; photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
Proud day for Harvard
Harvard Staff Writers
May 29, 2025
long read
Joy, unity, and gratitude as University celebrates 374th Commencement
Part of the
Commencement 2025
series
A collection of features and profiles
A collection of features and profiles covering Harvard University’s 374th Commencement.
All he got out was “Welcome,” before the crowd sprang to its feet to give a visibly moved President Alan Garber a standing ovation as he stood at the podium in the opening moments of Commencement. Across the Charles, University lawyers were presenting their case against a Trump administration move to block Harvard from enrolling international students. It was a graduation unlike others in its legal and political context but one that at its core remained deeply and distinctly personal. The blend of hope for the future, gratitude for family, friends, and teachers, and the poignancy of moving on were in evidence throughout the Yard. Here are some snapshots of the day.
Always remember: You might be wrong
In remarks to students, President Garber delivered a warning about the danger of getting too comfortable.
“The world as it is tempts us with the lure of what one might generously call comfortable thinking,” said Garber, “a habit of mind that readily convinces us of the merits of our own assumptions, the veracity of our own arguments, and the soundness of our own opinions, positions, and perspectives — so committed to our beliefs that we seek information that confirms them as we discredit evidence that refutes them.
“Though many would be loath to admit it, absolute certainty and willful ignorance are two sides of the same coin, a coin with no value but costs beyond measure. False conviction saps true potential. Focused on satisfying a deep desire to be right, we can willingly lose that which is so often gained from being wrong — humility, empathy, generosity, insight — squandering opportunities to expand our thinking and to change our minds in the process.”
Nearing the close of his address, he celebrated graduates as “the hope of this institution embodied — living proof that our mission changes not only the lives of individuals but also the trajectories of communities that you will join, serve, and lead.”
President Alan Garber processes into Tercentenary Theatre.
Stephanie Mitchell/Harvard Staff Photographer
‘Semper Veritas’
Early Thursday morning, tucked in a quiet, grassy nook in front of Holden Chapel, seniors gathered one last time to hear from Rakesh Khurana, the Danoff Dean of Harvard College.
In his final address to students before stepping down as dean, Khurana urged soon-to-be graduates to savor having reached such an important academic and personal milestone in their young lives.
“Enjoy this moment. Think of where you were four years ago, where you are today, and all that came in between, and embrace every second of this special day,” Khurana said.
He also urged students to use their time and talents to make positive contributions to the world. “Whatever your calling is in life, I encourage you to do good,” he said, later adding: “My fondest hope for all of you — that your education has helped prepare you to be good citizens and citizen leaders for our society. Go forth and make us proud.”
Khurana, who was named dean of the College in 2014, plans to return to the faculty of the Department of Sociology and Harvard Business School.
“I will miss you dearly, and it has been one of the greatest honors of my life to spend these last four years with you and to serve as dean of Harvard College,” he said. “Semper Veritas!”
Jean-Marie Alves-Bradford, M.D. ’92, and her son Malik Aaron Bradford III at Eliot House.
Stephanie Mitchell/Harvard Staff Photographer
Opportunities and inspiration
More than three decades after her own Harvard graduation, Jean-Marie Alves-Bradford, M.D. ’92, beamed as her oldest son Malik Aaron Bradford III ’25 received his degree in biomedical engineering.
“I’m just so proud of him and it’s wonderful to see him accomplish this,” the former Kirkland House resident said. “This place has so many opportunities that he’s been a part of, and he’ll continue to grow from.”
She continued: “He’s really matured quite a bit. It’s been nice to see that evolution. He’s really settled and comfortable in his own skin.”
Alves-Bradford and her husband, Malik Bradford II, said they were excited for their son’s next steps. The new Harvard alumnus already has a job lined up after Commencement, the couple proudly shared. Bradford II shared his hope that Malik’s pursuits can be “applied in a way that’s going to help him feel fulfilled.”
A few feet away, fellow Eliot House parent Linda Erickson shared her excitement at seeing her daughter, Sarah Erickson ’25, accomplish her childhood dream.
Linda Erickson embraces daughter Sarah just after she received her degree.
Stephanie Mitchell/Harvard Staff Photographer
“When she was 8 years old, she told me, ‘I want to go to Harvard someday.’ So, to see that dream realized over all these years has been absolutely amazing,” Linda said. “She has pushed herself so hard to achieve that goal and to get to this day has just been inspirational.”
Sarah, who was homeschooled in Cincinnati by her mother before starting high school, received her undergraduate degree in biomedical engineering. At Harvard, she danced and performed in musical theater with the Harvard-Radcliffe Modern Dance Company and became a staff photographer for the Harvard Crimson.
“She’s not the same girl I dropped off four years ago,” Linda said. “She’s built great memories here with all the people she’s interacted with. It’s been amazing.”
Despite threats, hope forfuture of higher ed
“Honestly, it still doesn’t feel real,” said Jesse Hernandez, about moving on from life at Harvard. “I’m first-generation too, so there’s a part of me that has trouble imagining what comes next after something like this.”
The College graduate who studied economics, resided in Lowell House, and plans to hunt for a job in finance this summer, was especially grateful his parents and younger brother could make the rare trip from Florida to offer their support. “It feels good to be celebrating with all the people that helped me get here.”
With many close friends who are international students, Hernandez said he’s worried about their future after the Trump administration’s effort to block Harvard from enrolling them.
“Everybody’s nervous. Just when you start to think things can’t get worse,” they do, he said. Despite the circumstances, Hernandez said he’s trying to stay positive.
“I’ve got confidence that we’ll see this through, and that higher education won’t die today.”
Jubilant graduates fill Tercentenary Theatre.
Photo by Grace DuVal
3 yearsafter knee tear, starting a new career
Danielle Ray’s journey to Harvard began with a knee injury. The professional squash player born in Calgary, Canada, had competed professionally since graduating from Cornell, but during the 2022 Canadian National Championships, she took an awkward step and tore her ACL, MCL, and meniscus all at once.
“It just got stuck on the floor as I was turning and just collapsed in,” she said.
Facing the prospect of multiple surgeries and many months out of the sport, Ray looked for something she could do in the meantime that could prepare her for the future. Her now-husband, who had graduated from Harvard with a master’s degree, suggested the Harvard Extension School.
A month later, Ray was enrolled in a master’s degree in information management systems. “I blew my knee out in June,” she said, “and I started the program in July.”
The program, Ray found, was a good mix of technical and policy-based courses. Her favorite course, “Fundamentals of the Law and Cybersecurity,” examined the legal, economic, and policy challenges that arise from cybersecurity threats. She found herself especially drawn to the policy components of the program and her work in agile project management — figuring out ways to solve dynamic, complex problems.
Because she could complete the degree online while taking one or two courses at a time, Ray could also move her life forward in other directions. She recovered from her surgeries, worked through physical therapy, and returned to the professional squash circuit — representing Canada at the international level. She competed in tournaments while pregnant and in January, gave birth to a baby girl.
Ray says she’s in a place right now “that’s a bit transitional.” She hopes to work herself into a policy-related position in the near future, building off interests she developed at Harvard. She still competes professionally.
But at Commencement Thursday with her family, she celebrated her accomplishment. “It’s almost three years to the day since I tore my knee,” she said. It would have been hard then to imagine all that would quickly follow.
Aidan Fitzsimons of Winthrop House said he paused his studies for several years before returning to Harvard. “I’m gonna miss this place,” he said.
Veasey Conway/Harvard Staff Photographer
Giving disadvantagedDetroit youth a boost
“I didn’t see this for myself,” said Courtney Ebonique Smith, a newly minted graduate of the Harvard Extension School with a master’s degree in industrial-organizational psychology.
Smith grew up in foster care before being adopted and when she graduated from high school, she was living in a homeless shelter. Her experiences led her to start the Detroit Phoenix Center, a nonprofit in Detroit that provides housing, academic, and workforce support to young people who are experiencing housing insecurity and other barriers to opportunities.
“We provide them with support so they can thrive,” she said, “and maybe even come to Harvard.”
A few years after starting the nonprofit at the age of 25, Smith looked for ways to gain skills that she could immediately use as its CEO. She found the Extension School, which allowed her to take courses both on campus and from home.
In 2020, she started the Extension School’s Nonprofit Management Graduate Certificate. When she finished, she enrolled in a master’s degree. The flexibility of the program allowed her to work whenever she had time to spare. “I was able to do it at night, on the plane, in the morning, during the day,” she said, laughing. “It’s very convenient.”
Smith said that her skills in fundraising and project management improved after taking classes in both subjects. Overall, she said, the program taught her “how to be adaptable and to juggle a lot of things at once.”
Looking back, Smith is proud of the journey that led to her graduating from Harvard. “I want every person to know that it doesn’t matter where you come from,” she said. “There are opportunities for you to be able to live out the dreams that you have for your life and to thrive.”
Graduates pose in front of Widener Library.
Photo by Grace DuVal
A real team guy
Scott Woods II is a person of loyalties.
First on the list of the economics graduate is his House, Cabot.
“I’m a big quad guy — very loyal to the quad,” he said, while toting the Cabot House sign used in the Commencement Exercises across the Yard. “I boast about how great it is, even though it catches a lot of flak.”
Woods said Cabot, which is on the “quad,” is seen by some as less desirable than the other Houses, which are closer to the main campus along the Charles River. And he gets it because he started out that way.
“I remember it vividly,” he said of the moment he got his housing assignment as a first-year. “You could hear a pin drop — no one was excited about it at first. But then as soon as we got out there, we just realized it was all a myth, and we had to make it what it was, which was a good time.”
Besides being a Cabot House booster, Woods is also a Crimson football loyalist, having been a wide receiver on the team.
“Harvard came in with a last-minute offer that changed my life. And since I committed to play here, my life has been on the upward trend,” he said.
Woods said he’s off to the University of Maine next year, where he’ll pursue an M.B.A. Originally from Virginia, he said in all seriousness that Cabot helped make Harvard home.
“The people in Cabot made me feel seen and made me feel comfortable. It made me feel like I had a family,” he said, grinning. “Being all the way out here you don’t really have too many people to interact with.”
Woods was joined on Commencement Day by his mom, dad, brother, and two grandmothers. He said they were proud of their Cabot House mascot.
“They thought I was the man. They wanted to get a picture with me,” he said.
Maryam Hussaini (center) cheers as her group of graduate students is recognized during the Commencement Exercises.
Veasey Conway/Harvard Staff Photographer
‘It’s surreal’
Jean Filo hustled to meet his parents after the Commencement ceremony, part of a departing wave of other Medical School graduates identifiable by the stethoscopes they wore along with their caps and gowns.
He paused for a moment to reflect on what his graduation meant not only to himself as an immigrant from Syria but also to his parents waiting eagerly to hug their son.
“It’s surreal,” he said. “Today is mostly about my parents and them enjoying this.”
During his time at Harvard Medical School, Filo worked in cerebrovascular research at the Beth Israel Deaconess Medical Center’s Brain Aneurysm Institute. He said he’s now heading off to Philadelphia to do a residency in neurosurgery.
But first, he said, rushing off, he had dinner plans with the parents.
Family pride — and impact
Caroline Maynes and Sierra Dorweiler have been watching their son and brother, respectively, for years, and, though they know him well, they’re still impressed. Nicholas Maynes, who graduated with a master’s degree in public administration on Thursday, has been on a yearslong journey that has taken him to war and back.
As the pair watched the Commencement unfold in Tercentenary Theatre, they said that Maynes has been entirely self-driven, starting with his education at West Point.
His Army service as a field artillery officer included deployment to Iraq during the liberation of Mosul. After that, he earned a master’s degree in business administration at the University of California at Berkeley before enrolling at Harvard to study at the Kennedy School.
“Academics has just been his passion,” said Caroline.
Watching her brother couldn’t help but have an impact on her, Dorweiler said. Maynes has always encouraged her to focus on what can be done, not what can’t, she added.
“I’m so proud because he’s been the one who’s pushed me to achieve academically,” she said. “He just makes it seem like pretty much anything is possible.”
Her goal: To help as many people learn as she can
Growing up in India, Devina Neema — who graduated Thursday from the Harvard Graduate School of Education — observed a major disparity between private and public schools. Her school had good classrooms and teachers and 40 hours of class every week. In public schools, students could get four or five hours of instruction, with few books and limited interaction between teachers and parents.
After graduating from college, Neema began teaching in public schools through a nonprofit program. The conditions weren’t ideal. At times, she led classrooms filled with 90 students. “It was a new world for me,” she said. “I realized this is where education needs to happen and get better.”
For different nonprofits, Neema worked across rural and urban areas to understand how students learned at different types of schools. How did they learn their first language? What were the math disparities? Were there any technological solutions?
To explore those questions more thoroughly, and to get a more formal education in teaching and how to change education at a systemic level, Neema looked to the HGSE’s master’s program in Learning Design, Innovation, and Technology.
At Harvard, Neema explored how people of different ages learn and how technology can augment it. She also studied how learners can develop transferable skills, such as social skills, and apply them to science, technology, engineering, and mathematics.
Having never formally studied education in a university setting, she was struck — and inspired — by the sheer amount of research her professors performed in their areas of expertise. “If you have to truly understand something at heart,” she said, “then you have to broaden your perspective but also narrow down your niche and go deep.”
With her program now complete, Neema plans to stay in the area so she can continue to learn and “build something here,” she said. After studying the education systems in many countries and the workings of international and humanitarian aid, she wants to help as many people learn as she can — with any tools she has.
Sheriff of Middlesex County Peter J. Koutoujian leads the processional into Harvard Yard.
Photo by Grace DuVal
What’s to come
Like many, College seniors Kylie Hunts-in-Winter and Taylor Larson weren’t quite sure what to expect from Morning Exercises on what is typically a joyful day.
Given the tensions sparked by Harvard’s legal battles with the Trump administration, they weren’t certain how graduating students would respond to University officials or the celebration.
“Some people were saying on [the social media app] Sidechat that they want to cheer for [President Alan] Garber, and other people. And so, I’m interested to see how this plays out,” said Hunts-in-Winter, a champion martial artist who studied sociology and Ethnicity, Migration, Rights.
The duo stood with Larson’s Adams House colleagues as undergraduates prepared to process into Tercentenary Theatre. Not long after, Garber and other University officials received robust cheers from the assembled crowd as they made their way toward the stage.
For Larson, a history and literature concentrator from Minnesota, the morning was one of conflicting emotions. While it was “exciting,” she confessed to also feeling “overwhelmed by everything that’s to come after this.”
Both identify as first-generation, low-income students. Larson plans to pursue a master’s degree in history in London, while Hunts-in-Winter, whose family is Lakota from the Standing Rock Reservation, intends to remain in the Boston area to pursue public service work with Native American communities.
“I am glad and I’m very grateful for my time,” said Larson. “I met all my best friends here and had a lot of opportunities because of Harvard funding.”
Dunster House ceremony: Lasting friendships
Residents of Dunster House returned to their home of the last three years to gather with parents, grandparents, siblings, and friends, receive degrees, enjoy lunch — and let it all sink in.
Graduate Minsoo Kwon, a Mather House resident, was at Dunster to celebrate her friend Hannah Ahn, whom she met five years ago during a gap year in Korea.
Kwon said the two, who have remained friends throughout college, will both be heading off to law school in the fall — with plans already in the works for frequent visits.
“I’ll be at Yale, and Hannah will be at Columbia,” she said. “Still along the Amtrak line.”
Ahn earned a degree in government while Kwon got hers in neuroscience. She’s interested in drug and healthcare policies that overlap law and science.
Sara Silarszka receives her diploma at Dunster House.
Photo by Grace DuVal
Two other friends sharing in the afternoon festivities were Sara Silarszka and Quincy Brunner Donley — first-year roommates who got along so well they stayed together for the next three years at Dunster.
“We were in a double for three years together, and so this is the first year we had our own rooms,” Donley said.
Asked whether they missed sharing the close quarters, Donley said, “I think I did,” followed by a quick “definitely” by Silarszka.
Both roommates made their mark in Harvard athletics — Silarszka, as a field hockey player, now with a degree in integrated biology, and Donley, a Nordic skier with a degree in economics.
Donley said after graduation, she’s moving back to her home state of Alaska to pursue professional skiing.
“At least for the foreseeable future,” she said.
Silarszka, who grew up in Virginia, said she is hoping to visit her old roomie. And she’s taking a gap year before applying to medical school.
“I just love living with my best friends,” she said. “You’ll just never be this close to so many people you love, so that’ll be hard to leave behind.”
Graduates entering Tercentenary Theatre.
Photo by Grace DuVal
Back to the beginning
Chidimma Adinna, a graduating senior from Adams House, left Nigeria at age 6 when her parents immigrated to California. Now she’s set to return, thanks to a fellowship to teach at a high school some of her family members still attend.
While her desire to return to Nigeria stems from her family history, the how and why owe largely to her studies at Harvard. A psychology concentrator, Adinna became interested in climate change during her time as an undergrad. As a fellow in Nigeria, she plans to promote sustainability and help the school take steps to fight the climate crisis. She’ll also act as a tutor and mentor students who want to go to college.
“Since I was younger, I was always trying to be connected to my community in Nigeria,” she said. “This has involved me donating clothes through organizations that I founded with my family, and it’s a mission that I’m trying to continue, even postgrad. It’s been evolving over the years I’ve been trying to give back to my community.”
Connecting flights?
Justin Biassou spent a lot of time in an airplane cabin on the way to his master’s degree.
Starting in 2022, he would occasionally commute from Seattle to Cambridge for in-person classes from Harvard Extension School, where he earned an A.L.M. in international relations.
But Biassou is comfortable in the air. He started flight training at 12 and got his private pilot’s license at 17. Even as he studied, he was working full time leading an air safety team for the Federal Aviation Administration.
Biassou took up his coursework in January 2022, when the COVID-19 pandemic still loomed over campuses, classrooms, and airports.
“I took one class per semester, and each one had this incredible group of students with all these different backgrounds — often they were working, too.”
Many of Biassou’s courses did take place online. But person-to-person time in Cambridge was well worth the flight, as were a few intensive January courses crammed into his time off from work.
At a time when “a lot of us just felt isolated, and very uneasy,” Biassou recalled, class “just really brought a lot of us together … These have become lifelong friends.”
The Extension School allowed Biassou a chance to expand his skill set in aviation safety. With new expertise in international relations, he hopes to “harmonize” safety efforts beyond U.S. borders, with authorities like the United Nations and the International Civil Aviation Organization.
His three-year, transcontinental balancing act may have earned Biassou “a lot of gray hairs.”
“But I had a really incredible support system: my significant other Michelle, my parents, my sisters,” Biassou said, as his family stood by. “They allowed me to focus on the things that needed to get done: Yes, 40 hours a week keeping aviation safe, then also working on my classes.”
Makena Tenpenny (center) embraces her fellow Harvard Graduate School of Education classmates as their class is recognized.
Veasey Conway/Harvard Staff Photographer
A child of immigrants gives back
Many faculty and graduates at Commencement ceremonies wore stickers, flowers, and other symbols in support of Harvard’s international students — now facing threats from the Trump administration.
For Daniel Roque-Coplín, J.D. ’25, the cause of safeguarding the rights of newcomers in America is personal — and the focus of his professional goals.
“Both of my parents are immigrants: My mom is from the Dominican Republic; my dad is from Cuba,” Roque-Coplín said, as he and his mother huddled before lunch. “They never in their lives dreamed that their son could go to a school like this one.”
His law school journey was not always easy — particularly at the beginning.
“First year, second year, you spend a lot of time in the library,” he said. “A lot of times, the studying can consume you, because you’re competing with everyone else, in a sense.”
Roque-Coplín said he was driven by a desire to help families like his own, with immigrant pasts and big ambitions in the United States.
Even before the latest tightening of immigration law and enforcement, the law did not always serve those families well, Roque-Coplín said.
He hopes to change that.
“Immigration law is intersectional, right? There are public-health needs, criminal needs, straightforward needs” related to legal status and asylum.
He had already begun that work in Cambridge as a student attorney in family practice with the Harvard Legal Aid Bureau, which offers free representation to low-income clients in Greater Boston.
Roque-Coplín acknowledged that he enters the legal professional at an acutely difficult moment for the families he hopes to serve. But he and other Law School graduates said they see that field as a chance to do urgent work.
“Through the grace of God, I’ve overcome — I’m here,” Roque-Coplín said. About the fights to come, “I’m nervous, I’m excited, and I feel, honestly, like nothing can stop me.”
Graduates wait to receive their diplomas at Lowell House.
Photo by Grace DuVal
A star’s turn
As the official ceremonies of Commencement Day wound down, families gathered on the steps of Widener Library for photographs with their graduates.
Elio Kennedy-Yoon showed particular patience with the many iterations of family pictures on offer: his three siblings, separately and together; his father, then grandfather; his girlfriend; then the whole clan together.
You might credit Kennedy-Yoon’s recent experience with celebrity, as an actor and singer in Din & Tonics, the College a capella group. Just last year, he made a splash online with a viral solo version of Barry Manilow’s “Copacabana.” Fan art, mashups, and the group’s world tour ensued.
After Commencement, Kennedy-Yoon wore two sashes: one honoring his Asian American heritage and another for LGBT pride.
Even before that viral moment, the last five years have been transformative for Kennedy-Yoon.
First, a gender transition during the pandemic, and a jarring move from Utah to Cambridge.
“I love Utah, but the people can be very conservative. I really found a community here that’s very accepting, very diverse.” (Among that community was Kennedy-Yoon’s girlfriend, a few years older — and “the love of my life,” he said with a smile.)
Still, as a queer Asian American with some online visibility, it hasn’t been possible to dodge hostility or derision. When Donald Trump was elected president the first time, Kennedy-Yoon was 13. In this tumultuous spring, he said it feels like a long time to have lived in conflict with the country’s political leadership.
That has made the University’s resistance to Trump administration mean all the more.
“In a weird way. I’ve never been prouder to be a Harvard student than right now,” Kennedy-Yoon said. “That we’re standing up for academia, for knowledge, for truth … and against tyranny.”
Ready to start
When Annabeth Tao was an undergraduate at UCLA, she worked as a research assistant for a professor focused on computer game animation. In her year at Harvard’s Graduate School of Education, she added to that experience a better understanding of how students learn, which she plans to blend into a startup focused on devising interactive games to help students become more creative in STEM studies.
When she arrived on campus in the fall, enrolled in the Ed School’s Learning Design, Innovation, and Technology master’s degree program, Tao had a vague plan to use the arts to enhance education. Over the course of her studies, she refined that ambition, in part through conversations with fellow students. In fact, some of her best memories of her time at Harvard are the brainstorming sessions with classmates.
She’ll have to find a job while getting the startup off the ground, but said that she’s excited about the chance to help unleash creativity among students and teachers, shaping “a dynamic learning experience for kids.”
Nation & World
Judge sides with Harvard on international students
Photo by Dylan Goodman
Alvin Powell
Harvard Staff Writer
May 29, 2025
3 min read
Extends order blocking government’s attempt to revoke participation in Student and Exchange Visitor Program
A federal judge on Thursday extended a temporary restraining order blocking the Trump administration from terminating Harvard’s rig
Judge sides with Harvard on international students
Photo by Dylan Goodman
Alvin Powell
Harvard Staff Writer
3 min read
Extends order blocking government’s attempt to revoke participation in Student and Exchange Visitor Program
A federal judge on Thursday extended a temporary restraining order blocking the Trump administration from terminating Harvard’s right to host international students and scholars. The restraining order was issued last week after the University sued in response to an attempt by the government to revoke Harvard’s Student and Exchange Visitor Program certification.
More than 5,000 international students and scholars at Harvard are at risk of losing legal status due to the revocation order, which was first conveyed in a letter from Homeland Security Secretary Kristi Noem and has sown fear and confusion among international students and scholars at Harvard and other universities. In its lawsuit, Harvard argues that the government’s actions violate the First Amendment, the Due Process Clause, and the Administrative Procedure Act. President Alan Garber has described the Trump administration’s efforts as retaliatory.
Responding Thursday to Judge Allison Burroughs’ decision to extend the temporary restraining order, the University noted the contributions of international students and scholars and pledged to continue to fight for its ability to welcome them to campus.
“Harvard will continue to take steps to protect the rights of our international students and scholars, members of our community who are vital to the University’s academic mission and community — and whose presence here benefits our country immeasurably,” a University spokesperson said.
The extension of the restraining order came as students, staff, and faculty celebrated Commencement in Harvard Yard. Garber received a standing ovation when he began welcoming remarks that included a nod to the University’s global community.
“Welcome members of the Class of 2025 — members of the Class of 2025 from down the street, across the country, and around the world,” he said, adding: “Around the world just as it should be.”
Elsewhere in the Yard and around campus, students, alums, and others welcomed Harvard’s success in court.
International students are “part of what makes Harvard one of the best universities in the world,” said Kevin Pacheco, an instructor at the Medical School. Caleb Thompson ’27, co-president of the Harvard Undergraduate Association, agreed.
“I’m obviously very happy about the news,” Thompson said. “International students are a part of all our lives. I’m not the first person to say this, but Harvard isn’t Harvard without international students … these are some of the most talented, intellectually capable students on our campus.”
He added: “For me it’s personal even though I’m a domestic student: I have eight international suitemates. They’re the most important people in my life.”
Sy Boles of the Harvard Staff contributed to this report.
Campus & Community
Verghese tells an American story
Photo by Grace DuVal
Liz Mineo
Harvard Staff Writer
May 29, 2025
5 min read
Physician-writer foregrounds immigrants’ contributions to Harvard and the nation, urges graduates to show courage, character in face of hardship
Part of the
Commencement 2025
series
A collection of features and
A collection of features and profiles covering Harvard University’s 374th Commencement.
Abraham Verghese underscored the vital role of immigrants in the life of the nation at Harvard’s 374th Commencement Thursday at Tercentenary Theatre. He was speaking from experience.
Born in Ethiopia to expatriate teachers from India, Verghese, a doctor and writer, began his medical studies in Addis Ababa but had to interrupt them as the country descended into civil war in 1974. After completing his medical studies at Madras Medical College in India, he arrived in Johnson City, Tennessee, as an infectious disease specialist in the mid-1980s, the early days of the AIDS epidemic.
Verghese, who teaches at Stanford, was the principal speaker at Commencement, which unfolded as a federal judge in Boston extended a temporary restraining order blocking the Trump administration’s revocation of Harvard’s ability to host international students and scholars. That action and others by the government were on Verghese’s mind as he delivered a passionate defense of immigrants and international students living, studying, and working in the U.S.
“When legal immigrants and others who are lawfully in this country, including so many of your international students, worry about being wrongly detained and even deported, perhaps it’s fitting that you hear from an immigrant like me,” he said.
He also spoke directly to the contributions of foreign-born doctors at hospitals across the country.
“We were recruited here because American medical schools simply don’t graduate sufficient numbers of physicians to fill the country’s need,” said Verghese, who spent two years early in his career at what is now Boston Medical Center. “More than a quarter of the physicians in the country are foreign medical graduates, many of them ultimately settling in places that others might not find as desirable.
“A part of what makes America great, if I may use the phrase, is that it allows an immigrant like me to blossom here, just as generations of other immigrants and their children have flourished and contributed in every walk of life, working to keep America great.”
Stephanie Mitchell/Harvard Staff Photographer
Pointing to his experience as a graduate of the Iowa Writers’ Workshop — his books include “Cutting for Stone,” “My Own Country,” and “The Covenant of Water” — Verghese credited America for enriching his life as an author. He quoted the novelist E.L. Doctorow: “It is the immigrant hordes who keep this country alive, the waves of them arriving year after year. Who believes in America more than the people who run down the gangplank and kiss the ground?”
He also praised Harvard President Alan Garber for resisting Trump administration demands for viewpoint audits and other measures, even as dramatic funding cuts imperil the University’s ability to carry out its research mission. Harvard deserves support and praise, he said, for “affirming and courageously defending the essential values of this university, and indeed of this nation.”
Closing his remarks, Verghese offered a few pieces of advice to the Class of 2025. First, he urged students to read fiction, because novels offer “powerful lessons about life” and can open a reader’s mind to unfamiliar lives and experiences. He was inspired to become a doctor in part by reading W. Somerset Maugham’s “Of Human Bondage,” he recalled.
“If you don’t read fiction,” Verghese said, “my considered medical opinion is that a part of your brain responsible for active imagination atrophies.”
Verghese also stressed the importance of character and courage: “Graduates, the decisions you will make in the future under pressure will say something about your character, while they also shape and transform you in unexpected ways. Make your decisions worthy of those who supported, nurtured, and sacrificed for you: your parents, your partners, your family, and your ancestors. Make your decisions worthy of this great university and the hardship it must endure going forward as it works to preserve the value of what you accomplished here.”
Lastly, drawing on the lessons he learned from AIDS patients he tended to Tennessee in the mid-1980s, Verghese asked students to take great care with the gift of time. Seeing men in their 30s and 40s face death was heartbreaking, he said, but he found comfort in the fact that many of them, at the end of their lives, cherished the company of family.
“They found that meaning at the end of a shortened life did not reside in fame, power, reputation, money, or good looks,” he said. “Instead, they found that meaning in their lives ultimately resided in the successful relationships they had forged in a lifetime, particularly with family.”
Verghese read to the crowd a letter he had shared many times before. In it, a young man dying of AIDS assures his mother that, having fulfilled many of his dreams, he has no regrets, and is grateful that his illness has allowed him to slow down to spend time with his family.
“I’ve enjoyed a life full of adventure and travel, and I loved every moment of it. But I probably never would have slowed down enough to really appreciate all of you if it hadn’t been for my illness. That’s the silver lining in this very dark cloud …
“If anyone ever asks you if I went to heaven, tell them this: I just came from there. No place could conceivably be as wonderful as where I’ve spent these last 30 years. I’ll miss it. I’ll miss you, mother. I’m so glad we made good use of this time to get to know each other again.”
After reading the last lines, Verghese exhorted students, “Cherish this special day. And above all, make good use of your time.”
Campus & Community
Kannon Shanmugam to join Harvard Corporation
Kannon K. Shanmugam.Gittings Global Photography
May 29, 2025
5 min read
Alumnus of College and HLS elected to University’s senior governing board
Kannon K. Shanmugam ’93, J.D. ’98, a prominent and prolific appellate attorney and alumnus of Harvard College and Harvard Law School, will join the Harvard Corporation as its newest member, t
Alumnus of College and HLS elected to University’s senior governing board
Kannon K. Shanmugam ’93, J.D. ’98, a prominent and prolific appellate attorney and alumnus of Harvard College and Harvard Law School, will join the Harvard Corporation as its newest member, the University announced on Thursday. Shanmugam will succeed Theodore V. Wells Jr., J.D. ’76, M.B.A. ’76, who departs the board after 12 years of service.
Citing his “deep devotion to Harvard and to the importance of academic values and academic freedom,” President Alan Garber and Senior Fellow Penny Pritzker announced Shanmugam’s election in a message to the Harvard community on Thursday afternoon.
“Kannon Shanmugam is one of the nation’s most accomplished and admired appellate attorneys, who has also served an array of educational institutions,” said Garber and Pritzker. “Beyond his extensive experience counseling and representing major organizations in complex matters, he is known for his intellectual acuity and curiosity, his remarkable work ethic, his warm and collegial manner, his adroitness in engaging people with varied points of view, and his commitment to academic excellence.”
Shanmugam has argued 39 cases before the U.S. Supreme Court and more than 150 other appeals in courts across the country, including all 13 federal courts of appeals and numerous state courts. Formerly a partner at the law firm Williams & Connolly and a member of the Office of the Solicitor General in the Department of Justice, Shanmugam is now a partner at Paul, Weiss, Rifkind, Wharton & Garrison, where he is also the founding chair of the firm’s Supreme Court and Appellate Litigation Practice, chair of its office in Washington, D.C., and co-chair of the Litigation Department.
Shanmugam has also served a number of educational institutions in advisory and governance roles, including as past chair of the board of trustees of Thurgood Marshall Academy, a public charter high school in Washington, D.C.; current trustee of both the American School of Classical Studies at Athens and the University of Kansas Endowment; and past trustee of the Association of Marshall Scholars.
“It’s an honor to have been asked to serve on the Harvard Corporation, and I look forward to contributing my perspective to the Corporation’s deliberations in the coming years,” said Shanmugam. “My reason for agreeing to serve is simple: I owe everything to Harvard. Harvard gave me opportunities I never would have had, and it exposed me to different people and new ideas.
“Harvard has gone through difficult times and faces substantial challenges, but it does so much good for the world,” he continued. “Harvard is one of our nation’s most important institutions, and when an institution has problems, I believe the solution is to work constructively to fix the problems, while holding true to its foundational commitment to academic excellence. I look forward to doing my part to help Harvard meet those challenges and to make the University a better, stronger place for the future.”
A native of Kansas, Shanmugam’s father was a professor of electrical engineering at the University of Kansas after his parents emigrated from India. In 1993, Shanmugam graduated summa cum laude from Harvard College, where he concentrated in classics and served as editor in chief of the Harvard Independent. He studied as a Marshall Scholar at Oxford, where he received a Master of Letters degree in classical languages and literature. Shanmugam was executive editor of the Harvard Law Review before graduating magna cum laude from Harvard Law School in 1998.
After law school, Shanmugam clerked for Judge J. Michael Luttig of the U.S. Court of Appeals for the Fourth Circuit and for Justice Antonin Scalia of the Supreme Court. He entered private practice as an associate at Kirkland & Ellis and later served as assistant to the solicitor general in the Department of Justice from 2004 to 2008.
Shanmugam practiced as a partner at Williams & Connolly for more than a decade after leaving the solicitor general’s office, rising to become one of the country’s most sought-after appellate lawyers. He served as co-chair of the American Bar Association’s Appellate Practice Committee and as the president of the Edward Coke Appellate Inn of Court — an organization dedicated to advancing the rule of law through example, education, and mentoring. Shanmugam is the only practicing American lawyer who is an honorary bencher of the Inner Temple, one of the four English Inns of Court. He has also taught Supreme Court advocacy at Georgetown University Law Center and is an elected member of the American Law Institute and a Federalist Society contributor.
One of six appellate lawyers ranked as a Star Individual by Chambers USA, Shanmugam was a finalist for The American Lawyer’s Litigator of the Year in 2022 and 2024, and he was named Appellate Litigator of the Year by Benchmark Litigation in 2021.
In accordance with the University’s charter, Shanmugam was elected by the members of the Corporation with the consent of the University’s Board of Overseers. He will begin his service on July 1 as Wells departs the board. Garber and Pritzker thanked Wells and noted his service in their message to the community.
“We owe profound gratitude to our colleague Ted Wells, who since 2013 has served the Corporation and the University superbly with his powerful mind, his formidable legal expertise, his strong commitment to academic ideals and principled decision-making, and his humane concern for others,” said Garber and Pritzker. “In Kannon Shanmugam, we are fortunate to have someone well positioned to carry forward and build on Ted’s remarkable legacy, while bringing fresh perspectives and valuable insights to the hard and important work ahead.”
The Harvard Corporation, formally the President and Fellows of Harvard College, was chartered in 1650 and exercises fiduciary responsibility with regard to the University’s academic, financial, and physical resources and overall well-being. Chaired by the president, the 13-member Corporation is one of Harvard’s two governing boards. Members of Harvard’s other governing board, the Board of Overseers, are elected by holders of Harvard degrees.
Campus & Community
‘Like we’re reaching a new period of human history’
Veasey Conway/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
May 29, 2025
4 min read
Fascination with artificial intelligence pulls Muqtader Omari back to his scholarly first love: Science
Part of the
Commencement 2025
series
A collection of features and p
A collection of features and profiles covering Harvard University’s 374th Commencement.
Growing up in Afghanistan, Muqtader Omari ’25 loved astrophysics, but the political climate of his country led him on a couple of detours — working as a writer and studying government — before he ultimately returned to his scientific roots to focus on artificial intelligence.
After he graduated from high school in Kabul, Omari launched a nonprofit called Talk Science, which aimed to educate young people on social media platforms. But he soon found education had political dimensions he hadn’t anticipated.
“I started noticing all these limitations that exist and was interested in learning more about where these came from,” said Omari, pointing to the barriers faced by Afghan girls seeking an education under Taliban rule. His curiosity led him to write for a newspaper in Kabul, and eventually to pursue higher education in the U.S.
At Harvard, where he is one of nearly 6,800 international students across the University, Omari opted to concentrate in government and in computer science. Throughout his undergraduate years, he sought to learn more about his birth country as the Taliban retook control of Afghanistan’s government. In 2023, the Adams House resident met lecturer in the Modern Middle East Mohammad Sagha through a course dedicated to regional order, U.S. wars, and the politics of Iraq and Afghanistan.
“What makes Muqtader unique is that while he has a compelling personal story, he never relied on that to solely inform his worldview,” said Sagha. “He’s intellectually rigorous and tries to objectively study and understand Afghanistan, its neighboring environment, U.S. foreign policy, and other factors through a balanced scholarly lens — that is rare to find.”
Sagha added: “He is very passionate about what is happening in his country and is eager to make a difference.”
“I preplanned a lot of my life in high school, and none of it worked out. I’ll let myself decide in the moment. I just hope I’m happy and I’m learning.”
Omari’s early intellectual leanings may have been with Afghanistan, but he was determined to push himself to meet students from all walks of life. About filling out his first-year roommate survey, Omari said, “I didn’t want to be with other international or Middle Eastern students. I wanted it to be as opposing to who I am as possible, because that’s what I thought Harvard was all about.”
He joined the Institute of Politics as a study group leader and the John F. Kennedy Jr. Forum Committee, where he assisted in the production of nonpartisan dialogues on politics, public service, and other affairs. But halfway through his four years, Omari realized that politics wasn’t for him. Missing the rigidity that science offered, he became fascinated with artificial intelligence.
“It’s mind-boggling to me,” he said. “It feels like we’re reaching a new period of human history.”
Omari’s plans after Harvard are unclear. “I preplanned a lot of my life in high school, and none of it worked out,” he said. “I’ll let myself decide in the moment. I just hope I’m happy and I’m learning.”
Eventually, he hopes to return to Afghanistan, although the political situation is too unstable now, he said. His family, including younger sisters, moved to the U.K. after the Taliban takeover. “I could never feel like I’m at home anywhere else but Kabul,” he said.
Sagha is confident Omari will be successful wherever he lands. “He, alongside other gifted Afghan diaspora, can play a positive role in representing their country and enriching our own society and knowledge here in the United States.”
Campus & Community
‘It’s the best feeling, helping a prosecutor, a judge, see someone’s humanity’
At Law School, Sophia Hunt discovers passion for defense — and rises to job once held by Obama
Anna Lamb
Harvard Staff Writer
May 29, 2025
5 min read
Stephanie Mitchell/Harvard Staff Photographer
Part of the
Commencement 2025
series
A collecti
A collection of features and profiles covering Harvard University’s 374th Commencement.
When Sophia Hunt found out she had been elected president of the Harvard Law Review in February 2024, she texted her family group chat: “What do Barack Obama and I have in common?”
That commonality of course, was being selected by their peers to lead the nearly 140-year-old student publication that has been influential in shaping American law throughout its history.
“The works that we publish can be read by justices, lawyers, professors, and students and can not only shape the law itself but also shape our orientation about what the law can and should be,” she said.
After she graduates with her Juris Doctorate, Hunt plans to enter the world of criminal defense. Once she passes the bar, that is. Her interest, Hunt said, stems from working for the Office of the Federal Public Defender after her first year of Law School.
“That was a really formative experience,” she said. “It was really nice to be able to put legal research and writing to practice.”
Hunt joined Harvard Defenders, a student practice that provides pro bono representation to low-income defendants in criminal show-cause hearings and assists clients looking to seal their records, among other legal issues.
Hunt also took part in the Tenant Advocacy Project at HLS helping represent clients facing issues such as revocation of Section 8 housing vouchers. She also provided representation and legal research assistance to incarcerated people through the Prison Legal Assistance Project.
In her last year at the Law School, she worked with Harvard’s Criminal Justice Institute.
“That was like being a baby public defender, where I visited clients in jail and stood up in court and wrote motions,” she said. “Sometimes it was just talking and listening to someone’s story and being the first person to hear them. That has been incredibly fulfilling.”
“I just find so much meaning in working and advocating on behalf of individual clients.”
Hunt graduated from Harvard College in 2019 with a bachelor’s degree in history and literature. From there she headed off to Stanford to pursue a Ph.D. in sociology.
But after three years of research and writing at the intersection of law and society and receiving her master’s, she felt a call to law school and took a leave of absence from her Ph.D. program.
“In the back of my head, I’ve thought — is being a lawyer the best way to help the individuals and communities that I care about? Should I be doing more policy-related work, or should I be thinking about academia and putting new ideas out there and trying to change the law from that standpoint?” she said.
“I just find so much meaning in working and advocating on behalf of individual clients,” she added. “It’s the best feeling, getting to tell their stories, and helping a prosecutor, a judge, see someone’s humanity.”
In addition to her course load and participation in groups that brought her into the courtroom, Hunt said she joined Harvard Law Review in her second year at HLS to “further invest” herself in the Law School community and flex her academic muscles.
Hunt went on to be elected by that community to lead the Law Review as its second-ever Black woman president, after ImeIme Umana, who was elected in 2017.
“Just being in the same sentence as her is a complete privilege,” Hunt said. “It was an honor to be in consideration of all these amazing former presidents, including ones who were Black. But for me, I hope that we’re past the hump of having first and seconds. I hope it’s become more normalized at this point — someone being elected because they’re perceived as being the best person for the job.”
Reflecting on her time in the top spot, Hunt said it was challenging and rewarding but overall not as much an exercise in shaping the voice of the Review as an exercise in management.
“When it comes to editorial decisions, what’s really helpful is that our entire body is involved in the articles that we publish,” she said. “I tried to reflect the body’s will and interest in carrying out those decisions. And getting to work so closely on so many brilliant pieces was just phenomenal.”
Maureen Brady, Louis D. Brandeis Professor of Law at Harvard Law School, said Hunt’s leadership skills should serve her well during challenging times.
“It’s an incredibly important moment in our world,” said Brady, who teaches property law and related subjects. “There’s so much conflict, and there’s incredible polarization. I think law school is about learning a common language that we can use to argue about things and to deeply disagree, but also to, hopefully, reach justice. Sophia is someone who really embodies that, who has led a wide range of people, and who has pursued a really interesting path here, toward justice.”
After she passes the bar, Hunt plans to clerk for a judge in Mississippi.
“Through law school, you read a bunch of judicial opinions and now to switch over and help in the crafting of judicial opinions … it’s going to be interesting to see things on the other side.”
She added: “I’m excited to eat well and meet a bunch of new people, and I think I have to get into college football.”
Campus & Community
Six honorary degrees awarded at 374th Commencement
Honorary degree recipients Rita Moreno (clockwise from top left), Elaine H. Kim, Abraham Verghese, Richard Alley, Esther Duflo, and Kareem Abdul-Jabbar pose for their portrait with President Alan Garber and Provost John Manning in front of Massachusetts Hall.Niles Singer/Harvard Staff Photographer
Lucia Huntington
Harvard Correspondent
May 29, 2
Six honorary degrees awarded at 374th Commencement
Honorary degree recipients Rita Moreno (clockwise from top left), Elaine H. Kim, Abraham Verghese, Richard Alley, Esther Duflo, and Kareem Abdul-Jabbar pose for their portrait with President Alan Garber and Provost John Manning in front of Massachusetts Hall.
Niles Singer/Harvard Staff Photographer
Lucia Huntington
Harvard Correspondent
long read
Recipients are Kareem Abdul-Jabbar, Richard Alley, Esther Duflo, Elaine H. Kim, Rita Moreno, Abraham Verghese
A collection of features and profiles covering Harvard University’s 374th Commencement.
The University conferred six honorary degrees during Thursday’s Commencement ceremony.
Kareem Abdul-Jabbar
Doctor of Laws
Kareem Abdul-Jabbar is known world-wide over as one of the greatest basketball players to ever play the game as well as a committed social activist and award-winning writer. As a player, he was the NBA’s all-time leading scorer for 39 years, with 38,387, until his record was broken in 2023 by fellow Laker great Lebron James. Abdul-Jabbar is a six-time NBA champion, and the league’s only six-time MVP. Time magazine dubbed him “History’s Greatest Player” and ESPN and The Pac 12 named him the No. 1 Collegiate Athlete of the 21st Century.
Abdul-Jabbar has a national platform as a regular contributing columnist for newspapers and magazines around the world. He currently publishes on kareem.substack.com, where he shares his thoughts on some of the most socially relevant and politically controversial topics facing our nation. He is a nationally recognized speaker and regularly appears on the lecture circuit.
President Barack Obama awarded Abdul-Jabbar the Presidential Medal of Freedom, the country’s highest honor for civilians. He has also received The Ford Medal of Freedom, The Rosa Parks Award, The Double Helix Medal, and Harvard University’s W.E.B. Du Bois Medal of Courage. Abdul-Jabbar holds eight honorary doctorate degrees and is a U.S. Cultural Ambassador, a title created specifically for him by former Secretary of State Hillary Clinton.
Abdul-Jabbar is a New York Times bestselling author of 17 books, most of which explore the often-overlooked history of African Americans, from the achievements of the Harlem Renaissance to forgotten Black inventors who changed daily life. He currently has several book and film projects in development.
He is an award-winning documentary producer and was twice nominated for an Emmy. He was featured in HBO’s most watched sports documentary of all time, “Kareem: Minority of One,” and he a writer/producer on Season 5 of “Veronica Mars.”
In 2015, the Basketball Hall of Fame created the Kareem Abdul-Jabbar College Center of the Year Award, and in 2021, the NBA created the Kareem Abdul-Jabbar Social Justice Champion Award.
Abdul-Jabbar is the California STEM Ambassador because of his commitment to youth education, and also serves on the Advisory Board for UCLA Health. Now 76 years old, he likes to say, “Only my jersey is retired.”
Richard Alley
Doctor of Science
Geologist Richard Alley, widely known as one of the best professors at Pennsylvania State University, is an expert who studies the Antarctic and Greenland ice sheets to predict coming changes in climate and sea level. A 2007 Nobel Peace Prize winner (with Al Gore), he has been honored for research, teaching, and service, including election to the U.S. National Academy of Sciences and The Royal Society, and has advised top government officials from both major political parties.
Educated at Ohio State University and University of Wisconsin-Madison, where he earned his Ph.D. in 1987, Alley has authored or co-authored than 400 articles for scholarly publications about the relationships between Earth’s cryosphere and global climate change. His research was the first to show that the last Ice Age ended abruptly and violently rather than as a result of gradual change, suggesting a warning to look to the past before making environmental decisions for the future.
Alley’s “The Two-Mile Time Machine,” a Phi Beta Kappa science book of the year, focuses not on the long-term changes that may have caused the ice ages, but on newly discovered “flickering” climate changes revealed by drilling through Greenland’s ice. The ice core showed sudden, immense climate shifts that have changed the Earth from livable to inhospitably frozen to unbearably hot.
Alley has warned that the U.N.’s “best estimate” of 3 feet of sea-level rise by the end of this century is misleading: “It could be 2, it could be 15 or 20,” he has said.
“People who study the history of climate desperately need a record,” he told Knowable Magazine in 2022. “I really do think that this understanding of the ice ages, the role of carbon dioxide, has been a key step in the full understanding of the role of carbon dioxide in our climate.”
Alley participated in the U.N. Intergovernmental Panel on Climate Change and presented the PBS TV miniseries “Earth: The Operators’ Manual,” based on his book of the same name. In it, he wrote, “Science is not the result of dispassionate machines spitting out Truth; it involves passionate humans pursuing truth and fame and next week’s paycheck, while satisfying curiosity at the same time.”
Esther Duflo
Doctor of Laws
Esther Duflo is the Abdul Latif Jameel Professor of Poverty Alleviation and Development Economics in the Department of Economics at the Massachusetts Institute of Technology, co-founder and co-director of the Abdul Latif Jameel Poverty Action Lab (J-PAL) and Chaire, Pauvreté et politiques publiques at the Collège de France. Her research seeks to understand the economic lives of the poor, with the aim of helping design and evaluate social policies.
Duflo has worked on health, education, financial inclusion, environment and governance, believing that “Evidence-based policies are the key to solving complex social issues.”
Known for the “Randomista Movement,” which uses randomized control trials to study poverty interventions, Duflo says that without these trials poverty reduction efforts do no more than simply hope for the best. From 2000 to 2012 the number of published economic studies relying on randomized controlled studies nearly quadrupled.
Duflo has written, “If you want to understand the root causes of poverty, you have to lookbeyond the symptoms,” which she defines as a lack of cash. “If we want to fight poverty effectively, we must first understand the lives of the poor.”
Duflo’s first degrees were in history and economics from Ecole Normale Superieure, Paris. She earned a Ph.D. in economics from MIT in 1999.
Duflo has received numerous academic honors and prizes, including 2019 Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel (with co-laureates Abhijit Banerjee and Michael Kremer), the Princess of Asturias Award for Social Sciences in 2015, the A.SK Social Science Award (2015), Infosys Prize in 2014, the David N. Kershaw Award in 2011, a John Bates Clark Medal in 2010, and a MacArthur “Genius Grant” Fellowship in 2009.
With Banerjee, she wrote “Poor Economics: A Radical Rethinking of the Way to Fight Global Poverty,” which won the Financial Times and Goldman Sachs Business Book of the Year Award in 2011 and has been translated into more than 17 languages. She also wrote “Good Economics for Hard Times.”
Duflo is a member of the National Academy of Sciences and a Corresponding Fellow of the British Academy.
Elaine Kim
Doctor of Laws
Elaine H. Kim is professor emerita of Asian American and Asian Diaspora Studies in the Department of Ethnic Studies at the University of California, Berkeley, where she was also chair of the Ethnic Studies Department, associate dean of the Graduate Division, faculty assistant for the Status of Women, and assistant dean in the College of Letters and Science.
Questions of who is represented and how are central to Kim’s work. At UC Berkeley, believing that, “If something you want does not exist, you can try to create it,” she helped establish the Ethnic Studies Department.
Kim has written, edited, and co-edited 10 books and directed or produced and co-produced three video documentaries, including “Labor Women” in 2002 and “Slaying the Dragon: Reloaded” in 2011. She received the Asian Pacific American Heritage Lifetime Achievement Award, the Association for Asian American Studies Lifetime Achievement Award, the State of California Award for Excellence in Education, and the Association for Asian American Studies Cultural Studies Book Award.
Drawn to questions of representation by Hollywood stereotyping (“Very early on, everybody was interested in representation and felt the importance of films and television in our fate. And so all the students could relate to the fact that, for men, there was only Charlie Chan. Bruce Lee wasn’t even a possibility because they wouldn’t let him play in the roles. And then for women, it was just as bad — Madame Butterfly and Dragon Lady,” she told the Cal Alumni Association in 2021), she has worked hard to correct misimpressions of the Korean community in the U.S. and Asians more broadly, though she pointedly dislikes hearing one person speak for an entire group. She has served as president of the Association for Asian American Studies and on the National Council of the American Studies Association. She also co-founded Asian Women United of California, the Korean Community Center of the East Bay in Oakland, and Asian Immigrant Women Advocates.
Kim earlier received an honorary doctorate of laws from Notre Dame University, honorary doctorates in human letters from the University of Massachusetts Boston, Amherst College, the Global Korea Award, and a Fulbright Fellowship.
Rita Moreno
Doctor of Arts
Rita Moreno is a triple-threat performer whose legendary performances include roles as Anita in “West Side Story,” for which she won the Academy Award for Best Actress in a Supporting Role; Louise in “Carnal Knowledge”; Miller in “The Electric Company” (a role in which she popularized the shout “Hey, you guys!”); Sister Peter Marie Reimondo in “Oz”; and recently, Abuelita Toretto in “Fast X.” She is one of only six women to have won an Emmy, Grammy, Oscar, and Tony.
She began her career at 9 years old, dancing in New York City nightclubs, and broke into movies two years later by dubbing Spanish-language films. Her first appearance on stage, opposite Eli Wallach, came in 1945, when she was still 13. She broke into movies in 1950 with “So Young, So Bad” and worked steadily in movies and television throughout that era. Her 43 wins and 51 nominations include honors from the American Latino Media Arts, Critics Choice, Golden Globes, BAFTA, Daytime and Primetime Emmys, Grammy, and NAACP Image awards.
Moreno broke barriers for Latines and others. A social activist, she worked with the Civil Rights Movement and was part of the March on Washington in 1963. She has championed racial, gender, immigration, education (she herself attended Public School 132 in Brooklyn but dropped out of high school at age16), and LGBTQ+ rights, and advocated for relief for Puerto Rico, her homeland.
Acknowledging that she was typecast early in her career, even having her skin darkened for her role in “West Side Story,” she believes she owes her professional longevity to her ability “to get up and dust myself off and keep moving forward.” Moreno has said, “No one’s going to tell me how to make my own choices. For too many years, everybody told me what to say and what to do and how to be.”
She has been awarded the Presidential Medal of Freedom, the Kennedy Center Honor, the Peabody Award, and the Medal for the National Endowment for the Arts. The 2021 Netflix documentary “Rita Moreno: Just a Girl Who Decided to Go for It” tells the story of her amazing 85-year Hollywood career.
Abraham Verghese
Principal Speaker Doctor of Humane Letters
Abraham Verghese is the Linda R. Meier and Joan F. Lane Provostial Professor in the Department of Medicine, Stanford University. He also leads PRESENCE, a multidisciplinary center that studies the human experience of patients, physicians, and caregivers.
He began his medical training in Ethiopia in 1974, but when a military government deposed Emperor Haile Selassie he immigrated to America and worked as a hospital orderly for a year. He has written that that experience made him determined to finish his medical training. He earned his bachelor’s in medicine in India, completed a residency in Johnson City, Tennessee, and a fellowship at Boston University School of Medicine.
Verghese returned to Johnson City in 1985 and was quickly overwhelmed by the rural AIDS epidemic. To tell that story, he attended the Iowa Writers’ Workshop, writing in 2009, “I found my purpose and it was to become a physician. My intent wasn’t to save the world as much as to heal myself. Few doctors will admit this, certainly not young ones, but subconsciously, in entering the profession, we must believe that ministering to others will heal our woundedness. And it can. but it can also deepen the wound.”
Since 1991 Verghese has published in The New Yorker, Granta, The Atlantic, The New York Times, and elsewhere. His first book, “My Own Country,” was made into a movie directed by Mira Nair; and his novel, “Cutting for Stone,” spent 107 weeks on The New York Times bestseller list. “The Covenant of Water,” his latest, was a New York Times bestseller, an Oprah pick, and is currently being made into a series by Netflix and Harpo Productions.
Verghese is a member of the Institute of Medicine of the National Academies and the American Academy of Arts and Sciences. In 2015 President Obama awarded him the National Humanities Medal, “For reminding us that the patient is the center of the medical enterprise. His range of proficiency embodies the diversity of the humanities; from his efforts to emphasize empathy in medicine, to his imaginative renderings of the human drama.” In 2023, he was awarded a Guggenheim Fellowship. This is his seventh honorary doctorate.
Campus & Community
A celebration for parents, too
Harvard grad Ayleen Villarreal (second from left), with her family. Photos by Niles Singer/Harvard Staff Photographer
Sy Boles
Harvard Staff Writer
May 28, 2025
5 min read
Moms and dads reflect on campus journey they shared with children
Part of the
Commencement 2025
series
A collection o
A collection of features and profiles covering Harvard University’s 374th Commencement.
Commencement season is a time to celebrate the achievements of graduates, but behind every individual success is a network of parents, family members, and friends whose unwavering support made each diploma possible — or at least easier. Four families shared their stories — and their pride — on the eve of graduation.
Full circle for family
Gunjan and Gurmeet Batra journeyed from Denver to celebrate their son, Arjun, who is graduating with a concentration in electrical engineering.
“It’s a very proud moment for our entire family,” said mom Gunjan in a bustling Harvard Yard on Wednesday. “It’s been lovely having him go through the process and through such a prestigious institution. It’s been wonderful. We’re very proud of him.”
Arjun picked electrical engineering because a professor inspired him, but the decision has a special meaning for his family: His grandfather was also an electrical engineer.
Arjun said his parents supported him every step of the way. “I’d call them every night and complain about a p-set or complain about a class, and they’d help me get through it. I would call them multiple times a day. Having their support in the background, being there always, has been incredible.”
Arjun Batra ’25 (center) flanked by family and friends in the Yard.
Gurmeet said it was a bittersweet moment for his son.
“On one hand, he’s graduating and moving on, exploring new ventures,” he said. “On the other hand, he’s going to miss this. College is the place you build memories. He’s going to miss all this.”
More than a game
Owen Fanning always knew what he wanted: to play volleyball at a top college.
For mom Carolyn, that meant years of driving him to practice and matches during his high school years in Needham, Massachusetts.
“Without great support, people don’t typically get here,” said Owen, a physics concentrator and outside hitter for the men’s volleyball team, as he thanked his mom for schlepping him to “all those tournaments.”
But Carolyn deflected the praise. “He got himself here for sure. We were just there to be the car driver.”
The Fannings enjoyed coming into Cambridge to watch Owen’s matches. Carolyn said the family will miss those outings but are gratified to see how far Owen has come.
“This was the dream,” she said. “For us, it was worth every effort we put into it.”
Alongside the Fannings at Class Day, the Diaks were celebrating their own volleyball success story.
Parents Nikki and Bradley were volleyball players themselves, and soon-to-be-graduate Callum grew up playing the game with them on Lake Ontario near their hometown of Kingston, Ontario, Canada.
“Without them, I definitely wouldn’t be as passionate as I am about this sport,” Callum said.
Owen Fanning (second from left) and Callum Diak (third from left), both ’25, with family members.
Nikki said she was proud of her son for taking the initiative to apply to Harvard as a foreign student, and that playing on a college team taught him about determination and resilience.
“He’s grown so much personally and education-wise,” she said. “We’re so proud of all he’s learned.”
‘She could have gone to any university, and she decided to come here’
Sandra Villarreal posed for a photo with daughter Ayleen in front of one of the most recognizable landmarks on campus: the statue of John Harvard.
For Villarreal and husband Sergio, who immigrated from Mexico before Ayleen was born, watching their daughter earn a Harvard degree was a milestone decades in the making. The couple and 15-year-old son Dylan made the trip from El Paso, Texas, to attend Commencement.
“I feel fortunate to have been able to bring my family here and to have been able to give her the opportunity to go to whatever university she wanted and follow her dreams,” Sandra said in Spanish.
Ayleen spent four and a half years in the U.S. Air Force before coming to Harvard and is graduating with a concentration in government and a secondary in global health and health policy. She plans on working in politics for a few years before going to law school.
“At Harvard, I found my love for the law,” she said. “I believe that laws, regulations, and policies affect a human being’s everyday life all the way to their biological cells. … I’m very, very thankful for Harvard academics, because I’ve learned a lot in the government department, and I’m very grateful to the professors. I will take everything they gave me and go and keep serving the United States.”
Ayleen said her path was different than most of her classmates, as a Mexican American, a first-generation student, and a female veteran at the College — at one point, there were only five others. But she hopes her experience will show others that difference is not an insurmountable barrier.
“I want females in my hometown, in El Paso, Texas, or in Texas in general, to know that it is possible to achieve your dreams despite being a minority in the United States,” she said.
“I feel very, very proud of her for everything she’s done. It’s a very great pride,” her father Sergio said in Spanish. “She took every opportunity. She had a lot of options for university; it wasn’t just one or two. She could have gone to any university, and she decided to come here. We’re very happy with her choice.”
Kareem Abdul-Jabbar arrives onstage to address the Class of 2025.Photos by Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Take a stand, Abdul-Jabbar tells graduating seniors
Alvin Powell
Harvard Staff Writer
May 28, 2025
5 min read
Writer and basketball legend speaks to the moment in Class Day address
Part of the
Commencement 2025
ser
A collection of features and profiles covering Harvard University’s 374th Commencement.
In early 1956, the Rev. Martin Luther King Jr. stood next to his bombed-out house in Montgomery, Alabama, and urged angry supporters to recommit to nonviolence, reassuring them that “if anything happens to me, there will be others to take my place.”
On Wednesday, basketball hall of famer, writer, and social justice champion Kareem Abdul-Jabbar said that he counts Harvard University and President Alan Garber among “the others willing to take Dr. King’s place.” Then he asked the Class of 2025 whether he can count on them.
“When a tyrannical administration tried to bully and threaten Harvard to give up their academic freedom and destroy free speech, Dr. Alan Garber rejected the illegal and immoral pressures the way Rosa Parks defied the entire weight of systemic racism in 1955,” said Abdul-Jabbar, addressing grads during Class Day ceremonies at Tercentenary Theatre. “As I look out over the crowd of eager faces today who are ready to launch their lives of successful careers, I wonder how many of you will also be among the others willing to take Dr. King’s place.”
Abdul-Jabbar’s 20-minute speech was the centerpiece of the two-hour Class Day ceremony, which is hosted by graduating seniors. The event also featured a farewell address from Danoff Dean of Harvard College Rakesh Khurana, who is departing his post after 11 years of service.
Reflecting on his own journey as an undergrad, which took him first to the State University of New York at Binghamton and then to Cornell University, Khurana recalled his time at Cornell as a major turning point — the moment when he stopped trying to be the person others wanted him to be and instead explored who he was, reading deeply and beginning to understand his own values. It was then, he said, that he realized education was more than just memorizing facts and getting good grades, but an experience that helps you appreciate life’s long journey.
In the next chapter of your life, he told students, you will be faced with choices about new jobs and challenges, choices between opportunities that are transformational and those that are merely transactional.
“Wherever you go next, the important question isn’t where you go now, but who you’re going to be,” he said. “May your road be a long one, full of adventure, full of discovery.”
Abdul-Jabbar, who followed up his record-breaking 20-year NBA career by becoming a successful writer, received standing ovations at the beginning and end of his speech. He said that his passion for social justice and civil rights stems from the Cleveland Summit, a meeting organized by a group of Black athletes and activists to interview boxer Muhammad Ali after Ali refused to participate in the Vietnam War draft. The group’s aim was to determine whether Ali’s claim to be a conscientious objector was sincere.
Ali convinced them that he was, but not everyone agreed: He was soon convicted of evading the draft and sentenced to five years in prison, a fine, and a three-year boxing ban. (The Supreme Court would overturn the conviction in 1971.) The episode, combined with King’s assassination, left Abdul-Jabbar shaken, prompting him to turn down an invitation to the 1968 Olympics. Civil rights, he said, felt like “a fading dream.”
“I couldn’t bring myself to become a smiling symbol of the promise of the United States to be a multiracial democracy when it was doing everything it could to not fulfill that promise,” Abdul-Jabbar said.
Choosing justice, Abdul-Jabbar said, usually comes with risk. Sometimes the risk is financial, he said; sometimes it’s physical. In any case, the stakes are always high.
“You have to decide whether you’re part of the old-timey fire brigades passing buckets of water down a long line of people trying to put out a fire or if you’re content to stand by and let it burn,” Abdul-Jabbar said.
And one victory is not enough, he said, urging grads to commit themselves to a lifelong fight.
“It is a never-ending battle that must be fought over and over,” Abdul Jabbar said. “After seeing so many cowering billionaires, media moguls, law firms, politicians, and other universities bend their knees to an administration that is systematically strip-mining the U.S. Constitution, it is inspiring to me to see Harvard University take a stand for freedom.”
In addition to remarks by Abdul-Jabbar, Khurana, and incoming HAA president Will Makris, Class Day included a moment of silence to remember two classmates: Luke Balstad, who died in November 2022, and Ryan Murdock, who died after a brief illness in October. Byron Gonzalez and Talia Levitt received the Richard Glover Ames and Henry Russell Ames Awards, which recognize graduating seniors for unsung service to the community.
Campus & Community
‘Stand up for the truth’
ROTC members representing the Air Force, Navy, and Army swore an oath to support and defend the Constitution during the commissioning ceremony in Sanders Theatre. Photos by Veasey Conway/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
May 28, 2025
4 min read
In ROTC address, Garber offers Churchill as model of courage in ‘face of
ROTC members representing the Air Force, Navy, and Army swore an oath to support and defend the Constitution during the commissioning ceremony in Sanders Theatre.
Photos by Veasey Conway/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
4 min read
In ROTC address, Garber offers Churchill as model of courage in ‘face of near constant opposition’
A collection of features and profiles covering Harvard University’s 374th Commencement.
Even in the face of near-constant opposition, have the confidence of your convictions and stand up for the truth, Harvard President Alan Garber urged 19 soon-to-be graduates on Wednesday during the annual joint Reserve Officers’ Training Corps (ROTC) commissioning ceremony.
Gathered with loved ones watching in Sanders Theatre, the Army, Air Force, and Navy cadets swore an oath to support and defend the Constitution and were pinned with two gold bars marking their elevation to military officer ranks. Each received their first salute as a newly minted officer from a family member, friend, or mentor chosen for the honor.
President Alan Garber shakes hands with Army grad Andrew Lim.
In his remarks, Garber recounted British Prime Minister Winston Churchill’s historic visit to Harvard on Sept. 6, 1943, to accept an honorary degree at a critical juncture of World War II. Churchill had long warned about the danger Adolf Hitler and Germany posed to the world but was met with skepticism and even ridicule “by those who chose to blind themselves to the truth that was unfolding before their eyes,” Garber said.
“Despite being dismissed as paranoid and pushed to the margins, Churchill had the courage to persist, to keep his eyes open and unblinking. His confidence even in the face of near-constant opposition offers a powerful and enduring lesson for anyone who seeks to stand up for the truth,” he said. “I hope that you will carry this lesson with you as you support and defend the Constitution.”
Garber presented a biography of Churchill by William Manchester (“The Last Lion: Winston Spencer Churchill: Alone, 1932-1940”) to each student and a coin featuring Memorial Hall on one side and on the other, a Veritas shield and 1916 — the year Harvard first welcomed ROTC to campus.
“You will all be amazed by what you can accomplish in the years ahead,” said keynote speaker U.S. Army Lt. Gen. Joseph McGee.
The students will embark on a wide range of duties next. Some will undergo basic officer leader courses at military bases around the country, while others will begin training to become intelligence officers, members of the Judge Advocate General’s Corps, pilots, and a missile and nuclear operations officer.
Lt. Gen. Joseph P. McGee of the Army, the keynote speaker and an adviser to the chairman of the Joint Chiefs of Staff, said the world is undergoing “significant geopolitical shifts” in Europe, across the Middle East, and the Indo-Pacific, and that the U.S. military is rapidly evolving to meet the changing landscape.
Many of the graduating students have a STEM education, McGee noted, a critical tool that will become even more essential as AI, drone warfare, nanotechnology, robotics, and cyber are “redefining the future of warfare and what it looks like.”
What hasn’t changed, McGee said, is the diversity of people who make up the military.
“You’re going to join a military community that represents every single element of American society,” he said. “It is still the true melting pot of the United States. Your success is going to depend on hard work, leadership, peer leadership, and your ability to relate to your fellow Americans and have them prevail in the face of daunting challenges.”
As future military leaders, McGee said, “It’ll be your job to bring this unique group of individuals to realize their potential, build cohesive, high-functioning, and lethal teams, and lead them into the future.” United by a sense of common purpose and love of country, “You will all be amazed by what you can accomplish in the years ahead.”
Army grads were Matthew Fitch, Eytan Goldstein, Chloe Hansen, Conner Huey, Morgan Kim, Carly Lehman, Andrew Lim, Matthew Sau, Jack Schwab, and Isaac Tang. Sworn in for the Navy was Jasmine Zhang. Air Force graduates were Sarah (Sally) Barksdale, Caitlin Beirne, Blake Chen, Emily McCallum, Jenny Peters, Elizabeth Sasse, Faith Schmidt, and Charles Whitehead.
Photo illustration by Judy Blomquist/Harvard Staff
Campus & Community
Hey you, hold onto your humanity. You’ll thank me later.
Alexandra Petri
Harvard Correspondent
May 28, 2025
5 min read
A little advice for the graduates — or, at least, one of them (you know who you are)
Part of the
Commencement 2025
series
A collection of features and
A collection of features and profiles covering Harvard University’s 374th Commencement.
Alexandra Petri ’10, formerly a Washington Post columnist, is currently a staff writer for The Atlantic. She won the 2025 Thurber Prize for American Humor for her book “Alexandra Petri’s U.S. History: Important American Documents I Made Up.”
OK, Harvard graduates. Listen. Many of you want to be doctors and lawyers and researchers and benefit the world in some large way. I’m not talking to you. But the odds are non-zero that somebody currently graduating will be the one guy who makes a ludicrous, cartoonish amount of money and the world worse (that’s zeugma! I was an English concentrator). This is addressed to him, just on the off chance that he is reading the Harvard Gazette. I want to answer the question I am sure is already plaguing him: After the cataclysmic Event happens that unravels society and sends me scurrying to my luxury bunker, how do I keep my guards loyal?
Great question! Let’s dive in.
Okay, you have your luxury bunker with its hydroponic garden, its decontamination chamber, and its secure boundary patrolled by guards. How, once money ceases to be a concept with any relevance to human interactions, do you keep those guards in their place? Remember, before, they were your employees. But now you are alone in your bunker, after the Event! Money no longer matters to them, and they are much stronger than you! Much stronger than anyone! That is why you hired them as guards.
What is it that people do for other people? Make them laugh? Bake them pies? Remember what interests them and ask them about it? Tell stories? Give good foot rubs? Yes! Better!
Oh, you weren’t thinking about that, were you? The special technology you invented to give billionaires a second, bonus set of teeth that descends in front of their original teeth, like a curtain, at the press of a button (I don’t know what billionaires want) may have lined your pockets back in the day, but now you’re alone in that bunker, and you have to justify why you should still be in charge. No algorithms here! No stock exchanges! It’s just you and that strong man you hired, that man whose name is almost certainly Greg (but what if you’re wrong? Can you afford to be wrong? Remember, your money is no good any longer!).
Now it is just you and Greg. You and Greg, and, I hope, his family. You did remember to pick up his family, didn’t you? When you all piled into the helicopter and came rushing here? That’s the first thing I would have recommended.
Society is over. Bang! You created a lot of value for your shareholders, enough value that you were able to commission a yacht too big for even God to lift, have yourself surgically enhanced to look more like the vampire Lestat, and purchase this glorious bunker on a small island. Now large swaths of the planet aren’t livable, for reasons that people would probably say are your fault, if they had survived the Event. You are going to be stuck in this bunker for a while. And unfortunately, your money is no good any longer. Which is a shame because you had such a lot of it! Some of it was even bitcoin. Not that that matters. You can try telling Greg (Is it Greg? Maybe it’s Jeff!) that you have some bitcoin for him and see what he does. Maybe it will make him laugh. Maybe that can be the start of something.
Think hard about your guards! What do they love more than anything in the world? Maybe you can stash some of it in the bunker! But what if it runs out? There’s no way to get more, because society (as previously stated) is over. After you have disposed of the last box of Jeff (Greg?)’s favorite cereal, what will you do? The factory where it used to be made is under the ocean, or possibly being overrun by some sort of Mad Max situation. What it is not doing is making cereal.
Think! Think! What do people love? The warmth of sunshine on their skin? Fresh fruit? The smell of the top of a baby’s head? Doritos? Laughter? Joy? The feeling of being seen? No, no! These answers are all wrong. It needs to be something that you can access after the Event! Something that you can stockpile in advance and store in a vault, to be released at intervals to your guards only if you enter a code that indicates you are still unharmed.
Or, wait. What is it that people do for other people? Make them laugh? Bake them pies? Remember what interests them and ask them about it? Tell stories? Give good foot rubs? Yes! Better! Maybe you can invent a machine that does that and sell access to it in the bunker, using a special coin of your own devising?
No, never mind, we are back to money again. Remember, money doesn’t exist anymore!
What is the thing that you have to offer others? What about you is worth preserving? Don’t tell me it’s absurd that you should have to justify your worth in this transactional way. Don’t tell me you are valuable simply because you are a human being who exists. I know that. But does Greg (Jeff?)?
Maybe you should have thought about that before you made all that value for shareholders and triggered the Event. You should have thought about that before you let the cereal factory sink under the sea. I am begging you to think about it.
Grant Jones. Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Healing through music
Grant Jones incorporated love of meditation and listening to R&B, hip-hop into dissertation on mindfulness interventions
Liz Mineo
Harvard Staff Writer
May 28, 2025
4 min read
Part of the
Commencement 2025
series
A collection of features
A collection of features and profiles covering Harvard University’s 374th Commencement.
Grant M. Jones was around 10 years old when he first contemplated becoming a psychologist. A curious child who loved to read and was being raised by his mother, aunt, and grandmother in the Mattapan neighborhood of Boston, he noted it in his journal.
Later he concentrated in psychology and began practicing meditation to cope with stress as a Harvard undergraduate. Now a doctoral candidate in psychology at Harvard, Jones reflects on how this personal practice became the focus of his professional life.
“Slowly over time, the impact the meditation practice had in my life really made it clear to me that I wanted to center meditation as a core part of not only my personal life, but also my professional life,” said Jones. “Clinical psychology became a practical way to center the study of contemplative practices in my career and to be able to bring those tools to others.”
“Clinical psychology became a practical way to center the study of contemplative practices in my career and to be able to bring those tools to others.”
Grant Jones
As part of the research for his dissertation, Jones developed music-based mindfulness interventions that aim to decrease stress and anxiety among underserved populations. Jones, who grew up listening to artists such as Aaliyah, Destiny’s Child, Usher, and Tupac, calls music “one of my first spiritual practices.”
“Like mindfulness, music is a clear conduit toward being present, being centered, being grounded. A lot of people within the Black community, and a lot of people in general, don’t really find mindfulness very compelling or inviting for a lot of reasons. Music is so intuitive. It is a potential vehicle that folks could use to access the practice of mindfulness to heal.”
Inspiration for Jones’ research was nurtured in classes on songwriting and performance that he took with Grammy-award winning jazz musician esperanza spalding, who doesn’t capitalize her name. Spalding, who was professor of the practice in the Music Department from 2018 to 2023, taught courses that helped Jones enhance his singing and songwriting skills. As a result, Jones was invited to be part of spalding’s album “Songwrights Apothecary Lab,” a collaboration between neuroscientists, psychologists, spiritual leaders, and music therapists that was “part songwriting, part guided research,” in spalding’s words, and a testament to her aspiration to heal through music.
In some ways, those courses inspired Jones to produce, as part of his dissertation, music-based mindfulness interventions as method of decreasing stress and anxiety in the Black and other disadvantaged communities. Spalding, Matthew Nock, Edgar Pierce Professor of Psychology, and leading Black Buddhist contemplative Lama Rod Owens, M.Div. ’17, offered mentorship and support throughout his project, but spalding’s influence was crucial, said Jones.
“Esperanza was truly one of the best forces to ever enter into my life. It was like a fairy tale moment where a hero of mine invited me to be a part of a work that was devoted to using research to support the composition of songs with healing practices and intentions. In terms of our personal journeys, there was a lot of overlap.”
“I deeply appreciate and recognize what a rare combination of qualities it is to have someone who can be very rigorous in the scientific research angle.”
esperanza spalding
In a voice message, spalding credited Jones’ research for “bridging music and mental wellness as therapeutic support tools for people struggling with anxiety, depression and other mental health challenges.”
“I deeply appreciate and recognize what a rare combination of qualities it is to have someone who can be very rigorous in the scientific research angle,” said spalding, “and Grant can also bring his poetic and musical sensibility to bridge the gap between those epistemologies, those ways of understanding how our bodies and beings are supported by music.”
Spalding became a musical collaborator in Jones’ dissertation project, which will include an album with music-based mindfulness interventions by Jones and guided meditations from Owens. A release date is in the works.
After graduation, Jones plans to work as a researcher at Massachusetts General Hospital, but eventually he would like to start his own lab focused on meditation, music, and other contemplative tools, including psychedelics, to help improve mental health and wellness among disadvantaged populations. He sees his work as part of a longstanding belief among African Americans in the healing power of music, a tradition that includes gospel music, freedom songs, the blues, jazz, and rock.
“For Black folks, so many musicians and artists have been influential in holding community and providing a guiding light in dark times for our community,” said Jones. “My work strives to be of service to Blacks but also to any communities that can benefit from it. It is open to anyone who feels supported by music.”
Melissa Shang. Photo by Grace DuVal
Campus & Community
Identifying barriers faced by people with disabilities
Nikki Rojas
Harvard Staff Writer
May 28, 2025
4 min read
Melissa Shang conducts ambitious survey for senior thesis, filling ‘major gap’ in scholarship
Part of the
Commencement 2025
series
A collection of features and profiles cove
A collection of features and profiles covering Harvard University’s 374th Commencement.
Melissa Shang had planned to become a disability rights attorney and had set her sights on studying sociology on a prelaw track. Once at Harvard, she quickly found a new possibility.
“My whole reason for wanting to go into disability rights law was to be able to support people with disabilities,” said Shang, who has a degenerative nerve disorder called Charcot-Marie-Tooth disease. “I realized I could do that within the field of psychology.”
Switching her concentration allowed the Waltham, Massachusetts, native to take a deep look at the barriers faced by more than 70 million Americans who report one or more disability. Her senior thesis, which draws upon a deep well of original survey data, tested the hypothesis that experiencing what social scientists call “minority stressors” is associated with increased risk of suicidal thoughts and attempts for people with disabilities.
Shang argued that the link between minority stressors and suicidal behavior was brought on by “greater perceived burdensomeness and thwarted belongingness.” She also set out to prove that greater “positive disability identity and community engagement” had the power to weaken the effect.
According to thesis adviser Mina Cikara, the Fredric Wertham Professor of Law and Psychiatry in Society, Shang identified a “major gap” in the field’s research and literature. “It’s incredibly important work,” Cikara said.
Upon landing at Harvard, Shang immediately set about forging her own campus community. First up was co-launching the Harvard University Disability Justice Club. The officially recognized student group, initiated during Shang’s first semester, has since grown to 140 active members.
“I always thought advocacy work to be a bit of a lonely experience, but being able to have this community has been really powerful,” said Shang.
“I always thought advocacy work to be a bit of a lonely experience, but being able to have this community has been really powerful.”
Melissa Shang
The Leverett House resident subsequently fell in love with the Harvard Noteables, a student-run, non-audition Broadway show choir, after attending a single rehearsal her first year.
“Then I went to more rehearsals, and I realized that it was an accepting space and so different from the environment that I was exposed to back at my high school,” Shang said. “The sense of inclusion, accessibility, and community that this club brought — that allowed me to rekindle my passion for singing — has been really incredible.”
In the classroom, Shang’s early years were spent seeking answers to important questions within the field of disability studies. “I started learning more about what the mental health system was for people with disabilities and how inaccessible it could be,” Shang explained. “It can be extraordinarily difficult to find providers who are disability-informed, and many people are denied mental health services because of their disability needs.”
She also learned how little attention the problem has received from academics. “When I looked into the research that’s been done about systemic barriers for people with disabilities, I found very little to no research about it,” she recalled.
As a sophomore, Shang enrolled in Cikara’s research methods course. It proved to be a pivotal decision. The course introduced Shang to Cikara’s work, which later helped Shang identify a set of minority stressors to investigate in her thesis, including discrimination, internalized stigma, and identity concealment.
Cikara initially counseled Shang against her “incredibly grand plan” of reaching out to various disability organizations for help distributing surveys to those they serve. But Shang could not be dissuaded. In the end, the strategy enabled her to survey hundreds of Americans with disabilities about their mental health experiences.
“This is a testament to her character,” Cikara observed. “She just did it. She pounded the pavement over and over again. She collected over 200 responses from people all over the country, many of whom have a wide variety of disabilities. That was no small feat.”
Ultimately, Shang’s findings only somewhat supported her theory that stigma experienced by people with disabilities relates to suicidal behavior. Shang noted that “internalized stigma” was one factor that was found to be associated with suicidal behavior. But the project still marks an essential contribution, Cikara said.
“What she’s done is seed the field with this incredible pilot dataset which she could spend years building,” she said.
Shang’s next chapter brings her to a clinical psychology doctorate program at Oregon State University. She plans to continue researching people with disabilities, their encounters within the mental health system, and the many barriers they face.
“Because people with disabilities are so valuable in society,” Shang said, “it’s important to keep conducting research that gauges their experiences and mental health — and to make an active effort to better support them and improve the way they’re treated.”
Lilian Smith.Niles Singer/Harvard Staff Photographer
Campus & Community
She left small town for Harvard but found herself looking back
Eileen O’Grady
Harvard Staff Writer
May 28, 2025
5 min read
Lilian Smith’s thesis honors history of quiet resistance in Coeur d’Alene, Idaho
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A collection of features and profiles covering Harvard University’s 374th Commencement.
When Lilian Smith left Coeur d’Alene, Idaho, to attend Harvard, she was eager for new experiences and a fresh start in a bigger city. She didn’t expect to ever look back. But during her junior year, a religion course on nationalism prompted her to re-examine her hometown from a new perspective.
“I didn’t learn much about it growing up,” Smith said, “but I feel it’s a history that could really benefit people in the town — so as to not repeat history. It’s important to talk about things that make people uncomfortable sometimes.”
Smith, a history concentrator with a secondary in chemistry, wrote her senior thesis on the establishment of the Kootenai County Task Force on Human Relations, a grassroots organization that has been instrumental in the fight against white supremacy in Idaho. It started as a group of concerned citizens who came together in opposition to the Aryan Nations, a neo-Nazi, white supremacist hate group that was headquartered just outside her hometown from 1978 to 2000.
Smith’s interest in the topic began in “Religion and Nationalism in the United States,” a course with Catherine Brekus, Charles Warren Professor of the History of Religion in America.
“From the very beginning, when Lilian first considered doing a project about Coeur d’Alene, she has been absolutely fearless,” said Carleigh Beriont, assistant director of undergraduate studies for the Committee on the Study of Religion, who advised Smith’s thesis. “Willing to dig into the darker recesses of the past to better understand why and how ideologies like that promoted by the Aryan Nations continue to resonate in her home community, happy to sit down with anybody and everybody who might have a story to tell, regardless of their political ideology or party affiliation. She has been resolute in her desire to portray Coeur d’Alene and its residents with nuance and care, challenging national media portrayals of her community and underscoring how shallow portrayals of the region have served as a draw for white supremacists.”
“From the very beginning, when Lilian first considered doing a project about Coeur d’Alene, she has been absolutely fearless.”
Carleigh Beriont
Smith did research in the archives of North Idaho College and Gonzaga University, and conducted formal interviews with locals, including the town’s former mayor, former and current members of the Task Force on Human Relations, leaders at the Human Rights Education Institute, a former member of the Aryan Nations, a police officer, an FBI agent, and a Republican Party leader in Kootenai County.
Her thesis describes how the Kootenai County Task Force on Human Relations grew from a few concerned citizens into a unified front of businesses, schools, churches, law enforcement, and politicians, working together to stop the spread of hate in the community. They offered victim support to residents who experienced religious or race-based harassment or violence from the Aryan Nations, advocated for state laws against malicious harassment, and raised $35,000 for human rights organizations during an Aryan Nations parade.
“Silence gives consent” became one of their biggest slogans, Smith said.
“These people really care about this work,” Smith said. “Many of these leaders saw the best in people in a way that I might not have, and that really shifted my perspective on my town.”
Even after Aryan Nations was bankrupted by a lawsuit in 2000 and vacated their property near Coeur d’Alene, the Task Force and its sister organization, the Human Rights Education Institute, continued to promote human rights more broadly, through education and diversity programming, awareness events, an annual human rights banquet, and Martin Luther King Jr. Day celebrations.
Even so, Smith’s research showed how national media narratives have continued to portray her hometown as a haven for intolerance. She believes this had a self-fulfilling prophecy effect, attracting an influx of residents who are now pushing back against the work of the Task Force.
“One of the themes of my thesis is the powerful role media narratives play in shaping the evolution of towns,” Smith said. “The town that exists today is not the town that existed in the ’70s, and it’s made the work of the Task Force and the Human Rights Education Institute increasingly difficult.”
After commencement, Smith will move to Washington, D.C., to pursue her longtime dream of becoming a teacher with the Teach for America corps.
Her feelings about not returning to Coeur d’Alene after commencement are complicated. Through her thesis research, Smith grew increasingly concerned about America’s deepening political polarization — fueled, she believes, by a trend of people moving to areas that better align with their political values, reinforcing ideological echo chambers.
“This is a national trend that young people are leaving their hometowns when they feel their values don’t align,” Smith said. “Many don’t return to reinvest in their communities. It’s really concerning.”
Nearly every Coeur d’Alene resident Smith interviewed for her thesis asked if she planned to return home after graduation. While she is excited for her next chapter in Washington, D.C., Smith said she couldn’t help but feel a pang of guilt each time she told them no. “That pushed me to think more critically about the fact that I was leaving and consider the possibility of returning someday,” Smith said. “It’s disheartening that so many people tend to leave rather than stay and work to address the issues impacting their community. Realizing the strength of those who’ve remained in the community for so long gave me a deep respect for them.”
Campus & Community
Ringing in tradition
Lowell House bell tower.Harvard file photo
Cynthia W. Rossano
Harvard Correspondent
May 28, 2025
4 min read
Dozens of bells will mark Harvard’s Commencement
Part of the
Commencement 2025
series
A collection of features and profiles covering Harvard University’s 374th Commencement.
In ce
A collection of features and profiles covering Harvard University’s 374th Commencement.
In celebration of the city of Cambridge and of the country’s oldest university, neighboring churches and institutions will ring their bells in recognition of Harvard’s 374th Commencement.
For the 38th year the bells will begin to ring at 12:15 p.m. Thursday, just after the sheriff of Middlesex County declares the Commencement Exercises adjourned. They will ring for approximately 15 minutes.
Bells of varying tones hold a place in history, as they summoned students from sleep to prayer, work, or study. The deep-toned bell in the Memorial Church tower, for years the only bell to acknowledge the festival rites of Commencement, will be joined by the set of bells cast to replace the original 17-bell Russian zvon of Lowell House that was returned in 2008 to the Danilov Monastery near Moscow. The Harvard Business School bell will be heard across the river. The historic 13-bell “Harvard Chime” of Christ Church Cambridge, the Harvard Divinity School bell in Swartz Hall, and the bells of the Church of the New Jerusalem, First Church Congregational, First Parish Unitarian Universalist, First Baptist Church, St. Paul Roman Catholic Church, St. Peter’s Roman Catholic Church, University Lutheran Church, Holy Trinity Armenian Apostolic Church, and St. Anthony’s Church will ring for the graduates.
Bells were already in use at Harvard in 1643 when “New England’s First Fruits,” published in London that year, set forth some College rules: “Every Schollar shall be present in his tutor’s chambers at the 7th houre in the morning, immediately after the sound of the bell … opening the Scripture and prayer.”
Three of the 15 bells known to have been in use in Massachusetts before 1680 were hung within the precincts of the present College Yard, including the original College bell and the bell of the First Parish Church.
Of the churches participating in the joyful ringing on Commencement Day one, the First Parish, has links with Harvard that date from its founding. The College had use of the church’s bell, Harvard’s first Commencement was held in the church’s meetinghouse, and one of the chief reasons for selecting Cambridge as the site of the College was the proximity of this church and its minister, the Rev. Thomas Shepard, a clergyman of “marked ability and piety,” according to the late Harvard historian Samuel Eliot Morison.
Another church ringing its bells in celebration is Christ Church Cambridge. The oldest church in the area, it houses the “Harvard Chime,” the name given to the bells cast for the church in anticipation of its 1861 centennial. Two fellow alumni and Richard Henry Dana Jr., author of “Two Years Before the Mast,” arranged for the chime’s creation. The 13 bells were first rung on Easter Sunday, 1860: each bell of the Harvard Chime bears in Latin a portion of the “Gloria in Excelsis.”
Referring in 1893 to the Harvard Chime, Samuel Batchelder wrote, “From the outset the bells were considered as a common object of interest and enjoyment for the whole city, and their intimate connection with the University made it an expressed part of their purpose that they should be rung, not alone on church days but also on all festivals and special occasions of the College, a custom which has continued to the present time.”
The old Russian bells of Lowell House, in place for 76 years, rang on an Eastern scale; the more newly cast bells give out a charming sound, as do the bells of the Cambridge churches joining in concert. A thoughtful student of bells wrote in 1939, “… church bells, whether they sound in a tinkling fashion the end of the first watch in the dead of night, announce the matins a few hours later, or intone the vespers or angelus, have a peculiar fascination. Chimes affect the heartstrings …”
Niles Singer/Harvard Staff Photographer
Campus & Community
Deep in the Amazon, local politicians resist gold miners — and inspire thesis
Christy DeSmith
Harvard Staff Writer
May 27, 2025
6 min read
Encounter during rainforest trip leads Eduardo Vasconcelos to research focus
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A collection of features and profiles covering Harvard University’s 374th Commencement.
Reaching the tiny settlement, located deep within the Amazon rainforest, required several hours of travel by river boat.
“When we finally got there, we were immediately greeted by the mayor,” recalled Eduardo Vasconcelos ’25, who reached the far-flung municipality as a volunteer delivering medical supplies during the pandemic. “He took us to see the public school and the public health facility, all of which was managed locally. I was just mesmerized. I thought, ‘Wow! This is the most fascinating experiment in self-governance I’ve ever seen.’”
The encounter stuck with the double concentrator in economics and government, stirring old passions and eventually shaping his senior thesis. Vasconcelos set out to investigate what prevents elected officials like the one he met from falling in with illegal gold miners. Brazil’s federal government has banned these black-market operators, who rely on a process that pumps the environment with toxins. But the miners have proven effective at enlisting cooperation from some of the rainforest’s secluded local powers.
“People tend to look at policy in the Amazon as something that is determined by national administrations,” said Frances Hagopian, the Jorge Paulo Lemann Senior Lecturer on Government and one of three faculty advising the thesis. “There are those who are more protective of the environment and there are those who lean more toward developing the Amazon’s resources. What Eduardo did that was different was look below the level of national government.”
Vasconcelos, who grew up amid a family of civil servants in Brazil’s federal capital of Brasília, was interested in government from a young age. He was just 14 years old when he started working with teen trauma survivors. A wave of violent threats against the country’s public schools later inspired him to co-found Jovens Líderes pela Paz (Young Peacebuilders), a nonprofit that trains Brazilian students in de-escalation and advancing mental health supports.
Vasconcelos also worked on education issues as a government volunteer while still in high school. During his senior year, a federal scholarship enabled his first visit to Cambridge for the Harvard Model United Nations program. “I immediately fell in love with the institution,” he recalled.
At the time, then-Brazilian President Jair Bolsonaro was actively freezing public funding for universities while taking shots at certain humanities and social science disciplines. “That really motivated me to try to come,” said Vasconcelos, whose application was supported by the Jorge Paulo Lemann Fund. “It would allow me to study what I love.”
“When we talk about protecting the rainforest, we don’t always think about how we can better support local governments.”
Eduardo Vasconcelos
As a College first-year, he made his first trip to the rainforest with the nonprofit G10 Favelas, which transported medical supplies to Brazil’s small communities during the pandemic. Inspired by the responsive democracy he saw practiced in a remote Amazon outpost, Vasconcelos subsequently landed spots on two immersions in the region organized by the David Rockefeller Center for Latin American Studies (DRCLAS).
“I feel like the Amazon is what bonds every Brazilian together,” Vasconcelos said, noting that Brazilian Chief Supreme Court Justice Luís Roberto Barroso, a senior fellow at the Kennedy School’s Carr Center for Human Rights Policy, helped him home in on the rainforest as a research focus. “I see an opportunity to rediscover our sense of identity in the Amazon’s conservation and its future.”
Vasconcelos learned that illegal gold mining, on the rise since the early 2000s, contributes not only to deforestation and CO₂ rise. The extractors’ reliance on mercury and cyanide, used to isolate gold from river sentiment, contaminates water and air alike. Widespread mercury poisoning, with its devastating harms to the human nervous system, has been found in corners of the rainforest where unlawful mining is prevalent.
“He became very interested in why some local governments seem to allow this and others don’t,” said Hagopian. “And it turned out that the answer was not as simple as, some municipalities have the gold and others don’t.”
Vasconcelos kicked off his research project by indexing the influence of criminal mining interests over local governments. He focused on 50 municipalities in the Brazilian state of Pará, home to more than half of all illegal gold mining in the Amazon, finding some level of capture in 13. Advising the thesis with Hagopian were Government Professor Steven Levitsky, a Latin America expert, and Rio de Janeiro native Marcia Castro, a demography professor at the T.H. Chan School of Public Health.
In search of deeper understanding, Vasconcelos next turned to assessing a host of political variables in each municipality. “Most political scientists and economists who study illicit economic activity assume that it flourishes where states are weak,” Hagopian explained. “What’s interesting about what Eduardo found is that it’s not the weakest local governments that play host to a lot of this activity. It’s actually local governments with some capacity.
“They have enough trained bureaucrats to give legal license to mine on land reserved for environmental protection or Indigenous nations,” she continued. “They have enough resources to build new infrastructure.”
Instead, one-party rule emerged as the most predictive factor. “The specific result shows us that when there is more diversity of parties, we see a lower likelihood of gold miners running for election or funding campaigns,” Vasconcelos explained, pointing to Brazil’s diverse political landscape with more than 30 parties.
In a separate chapter, the Kirkland House resident and former World Bank intern went deep on the social impacts of this brand of corruption. He found that rates of deforestation doubled in the Amazon’s captured municipalities, while these communities saw decreased investment in education and public health.
“We also see war-level homicide rates — the highest in the country,” Vasconcelos added. “Our data show that this is not a sustainable economic activity. It doesn’t bring better quality of life for the local population.”
The bottom line, he concluded, is that local government is the first line of defense against a profoundly damaging industry. DRCLAS awarded Vasconcelos its 2025 Kenneth Maxwell Thesis Prize on Brazilian Studies this week.
“When we talk about protecting the rainforest, we don’t always think about how we can better support local governments,” said Vasconcelos, a Schwartzman Scholar who will move to Beijing this summer for a one-year, fully funded master’s program in global affairs at Tsinghua University. “I’d like to see more research looking at this intersection.”
Campus & Community
Entering ‘our problem world’
Danoff Dean of Harvard College Rakesh Khurana (right) with the Rev. Matthew Ichihashi Potts (from left), President Alan Garber, and Karen Thornber, president of the University’s PBK chapter.Photos by Stephanie Mitchell/Harvard Staff Photographer
Max Larkin
Harvard Staff Writer
May 27, 2025
5 min read
University honors — and challenges — newly ele
Danoff Dean of Harvard College Rakesh Khurana (right) with the Rev. Matthew Ichihashi Potts (from left), President Alan Garber, and Karen Thornber, president of the University’s PBK chapter.
Photos by Stephanie Mitchell/Harvard Staff Photographer
Max Larkin
Harvard Staff Writer
5 min read
University honors — and challenges — newly elected members of Phi Beta Kappa at ceremony
A collection of features and profiles covering Harvard University’s 374th Commencement.
Dozens of graduating scholars elected to the Phi Beta Kappa Society gathered in Sanders Theatre Tuesday morning.
They were called to order by Karen Thornber, president of the University’s chapter of the venerated honor society, the Harry Tuchman Levin Professor in Literature, and professor of East Asian languages and civilizations.
Thornber noted that students are elected, not merely for their near-spotless GPAs, but for their “depth and breadth” as scholars.
And she set a tone for the two-hour ceremony: commending the more than 200 elected students for this “tremendous honor,” then charging them with a responsibility to “continue your love of learning [and] inspire others to do the same.”
In prayer and oration, poetry and song, the event also acknowledged the troubled moment — notably, the University’s ongoing conflict with the Trump administration.
As he blessed the event, the Rev. Matthew Ichihashi Potts, Pusey Minister in the Memorial Church, invoked “a spirit of bravery.” And in a hymn with lyrics drawn from Langston Hughes, the Harvard University Choir enjoined graduates “to sit and learn about the world / Outside our world of here and now / Our problem world.”
Seated on the theater’s floor, the graduating members formed a cosmopolitan group: Over their gowns, many sported saris and hijabs, regalia from racial and ethnic affinity groups, and sashes marking home countries from Thailand to Brazil.
On stage were the officers of Harvard’s chapter and the three members of faculty who’d been awarded the chapter’s annual teaching prizes: Remo Airaldi in Theater, Dance & Media, Samantha Matherne in philosophy, and Steven Levitsky in government.
In keeping with traditions that stretch back to John Quincy Adams and Alfred Kazin, Henry Wadsworth Longfellow and Elizabeth Bishop, this year’s newly elected members heard from both a poet and an orator.
The poet was Arthur Sze — the son of Chinese immigrants who first dropped calculus for verse in a lecture hall at MIT over 50 years ago. Against his parents’ better judgment, Sze went on to Berkeley, a National Book Award for Poetry in 2019, and being honored as the first poet laureate of his adoptive hometown of Santa Fe, New Mexico.
Poet Arthur Sze reads original works.
In brief remarks, Sze called on the graduates to take risks and to attend to the interconnectedness — to neighbors and nature — at the heart of his own poetry. Of juxtaposition, Sze said, it “is more than mere artistic technique,” but “a vision of how to share our world.”
Reading his 2021 poem “Farolitos,” Sze sought to prepare his audience for the setbacks and wrong turns that are sure to mark their lives off-campus:
in this life, you may try, try to light a match, fail,
fail again and again; yet, letting go, you strike a tip one more time
when it bursts into flame —
Meanwhile, this year’s oration was delivered by Rakesh Khurana in one of his last acts as the longest-serving dean of Harvard College.
After 11 years leading the college, Khurana — who has dual appointments in sociology and at the Business School — warned that Harvard and other elite universities have a role to play in overcoming a “legitimacy crisis” now facing them.
“[Even] if we teach values of equity, selective institutions are seen as gatekeepers of privilege — hoarding opportunities rather than extending them,” Khurana said. And too often, he added, graduates of exclusive schools fail to use their capacities “in the best interests of the broader society.”
As he wrapped up an address once delivered by Ralph Waldo Emerson, Khurana contemplated the weightier meanings of the University’s motto: veritas.
In a time of deep division, where “confidence substitutes for understanding [and] complexity is flattened by outrage,” Khurana said that “truth — veritas — emerges slowly. It demands humility, skepticism, and the willingness to revise one’s views.”
Khurana cited his own work on efforts to foster “intellectual vitality” at the College as an effort to show veritas in action, as well as President Alan Garber’s resistance to federal demands. (Garber, who was seated onstage, drew a standing ovation at Khurana’s mention.)
As the event wound down, students and their families spilled into the transept of Memorial Hall to take photos and exchange greetings with classmates.
Nicolás Domínguez Carrero, one of the chapter’s four undergraduate marshals, found Khurana’s speech — and the ovation for Garber — “very moving.”
“I feel very proud to be a PBK scholar, and a Harvard student, at this moment,” he said, flanked by family from both Texas and Colombia. “I think Harvard’s doing an amazing job standing up for academic freedom and democracy, writ large. It is a time of crisis, but if there’s an institution that can weather this storm, it’s Harvard.”
Meanwhile, Levitsky, author of the bestsellers “How Democracies Die” and “Tyranny of the Minority,” was humbled by his teaching award.
But, he added, “The most wonderful thing about the ceremony was sitting on stage, watching the faces of the students. In this age of cynicism, I was blown away by how absorbed, how sincere they were… It really renewed my faith.”
Campus & Community
Fight for education, Garber urges grads
President Alan Garber addressing the Class of 2025.Niles Singer/Harvard Staff Photographer
Anna Lamb
Harvard Staff Writer
May 27, 2025
4 min read
‘Everything we might achieve is grounded in knowledge,’ says president in Baccalaureate address
Part of the
Commencement 2025
series
A
A collection of features and profiles covering Harvard University’s 374th Commencement.
In his second Baccalaureate address, Harvard President Alan Garber stressed to the Class of 2025 the importance of education, and those who impart it, for advancing knowledge.
“The best way to acknowledge Harvard — and what this time has meant to you — is to advocate for education,” Garber told students gathered at Tercentenary Theatre on Tuesday afternoon. “Everything we might achieve — morally, scientifically, technologically, and even economically — is grounded in knowledge. Where else are you more likely to find a path to knowledge and all that it unlocks for humanity than in education?”
Garber’s address capped this year’s interfaith ceremony celebrating undergraduates, a tradition dating back to Harvard’s first Commencement in 1642. The president’s plea to stand up for education comes amid funding cuts to the University by the federal government that will affect research across disciplines, including medicine and Garber’s area of expertise — economics.
Graduating seniors at the conclusion of the Baccalaureate service.
In his speech, Garber — who graduated summa cum laude from Harvard College in 1976 — took a moment to thank the educators in his life who led him to his career path, and he urged the soon-to-be graduates to do the same. In particular, he made note of his resident tutor in Dunster House, Jerome Culp, who told him to switch his concentration from biochemistry to economics.
“That conversation with him changed my life. I still think about it all these years later. Who inspired you? Who gave you the attention and gentle nudging you needed exactly when you needed it? Who kindled your true ambition? Send that note that you have been meaning to send to a mentor who meant more to you than they might realize.”
Throughout the ceremony, faith leaders from across the University congratulated the Class of 2025, and blessed their future endeavors. And, like Garber, a few of the speakers chose to honor the past.
“If you are here today, it’s because you are descended from people from around this globe who have survived deprivations and immigrations and persecutions and liberations, just so you could sit here on this Yard today,” said the Rev. Matthew Ichihashi Potts, the Plummer Professor of Christian Morals and Pusey Minister in the Memorial Church.
He continued, “You are the answer to your ancestors’ hopes and prayers. You are their dreams come true. It’s not just the past that lives in you — the future does too, because you have your own hopes and dreams and wishes and visions of all that you might be and all that you will become from this point forward.”
Gloria White-Hammond reflected on the influence of generations previous, noting marked differences from her own graduation from Harvard in 1972.
The Rev. Gloria White-Hammond, a retired physician and the current Swartz Resident Practitioner in Ministry Studies at Harvard Divinity School, also reflected on the influence of generations previous, noting marked differences from her own graduation from Harvard College in 1972.
“The relative diversity of your class compared to ours is a compelling indicator that we have been faithful to our callings,” she said. “And because the struggle continues, I want you to know that we are not here to pass our torches to you. Yes, we are old, but no, we are not dead. We are here to stoke the fire of your torch.”
Garber closed out by wishing one final good luck to students before Commencement on Thursday.
“May these final 44 hours, give or take some minutes, be filled with opportunities to celebrate how far you have traveled since your arrival. You have done so much. Rest on your laurels, but not for too long. The world, with its countless magnificent destinations, awaits you.”
Campus & Community
Finding common humanity, modern lessons in antiquity, a path forward
Graduates Thor Reimann (from left), Yurong “Luanna” Jiang, and Aidan Scully will deliver speeches Thursday at Commencement.Photos by Veasey Conway and Stephanie Mitchell/Harvard Staff Photographers and Grace DuVal
Jacob Sweet
Harvard Staff Writer
May 27, 2025
long read
Yurong ‘Luanna’ Jiang, Aidan Scully, T
A collection of features and profiles covering Harvard University’s 374th Commencement.
On Thursday, three graduating students selected in a University-wide competition will deliver speeches at Tercentenary Theatre — one of the oldest of Harvard’s Commencement traditions.
The student orators are Yurong “Luanna” Jiang, a graduating master’s student at the Harvard Kennedy School who will deliver the Graduate English Address; Aidan Scully, a graduating senior who will deliver the Latin Salutatory; and Thor Reimann, also a senior, who will deliver the Senior English.
Stephanie Mitchell/Harvard Staff Photographer
‘Guard Our Humanity’
Yurong “Luanna” Jiang
Growing up in Qingdao, China, Jiang realized that education was a way to change the trajectory of her life. And it did.
High test scores earned her a full scholarship to a high school in Cardiff, Wales. She attended Duke University for her undergraduate education and will represent Harvard Kennedy School as the University’s Graduate Orator.
One of her friends had the same early understanding about education. But while Jiang had plenty of time to study, her friend — the daughter of fishmongers — had to help before and after school at her parents’ shop.
“It’s almost like you’re standing at a railway,” Jiang said, “and you know you have to hop off. Otherwise, your life will always be the same.” Jiang’s path shifted, and her friend’s didn’t.
The disparity got Jiang thinking about a question that would guide her educational journey: “What does it mean to have equality, fairness, and social justice?”
In Cardiff, where Jiang arrived not knowing English, she became interested in economics. “I trace it back to middle school,” she said. “When you see those hardships, why do they happen? What would the solution be?”
She continued studying economics at Duke and became increasingly interested in philosophy and politics, reading the work of thinkers such as John Stuart Mill, Karl Marx, and William L. Rowe. To Jiang, economics felt like learning to drive a car, and philosophy felt like learning where to take it.
She also hosted a boxing club, having learned the sport growing up. Despite standing at around 5 feet, 3 inches tall, Jiang often prepared for competitions by sparring with men.
“It strengthens your character,” she said. “You have to look at them eye-to-eye and not be scared — because if you close your eyes, you cannot block the punch you can’t see, and you cannot hit a target you cannot see.”
Jiang worked in private-sector finance after Duke, thinking she might become an economist, but she felt the work was too far removed from the people she wanted to serve. The instinct brought her to the Kennedy School’s two-year M.P.A./I.D. program in international development.
She joined a class of 77 students from 34 countries. As she arrived, she writes in her address, “the countries I knew only as colorful shapes on a map turned into real people — with laughter, dreams, and the perseverance of surviving the long winter in Cambridge.”
She found her fellow students as idealistic as she was about supporting communities across the world — and one another on campus. When classmates lost loved ones or went through other tough experiences, friends from the program came to their aid, making sure they were eating and were not lonely.
“It makes us realize that this kind of empathy or human connection is beyond the countries,” she said.
She also continued studying philosophy, taking a class, and later a tutorial, with Arthur Isak Applbaum, Adams Professor of Political Leadership and Democratic Values. Reading philosopher Michel de Montaigne’s thoughts on recognizing the humanity of those very different from himself helped inspire her, more than 400 years later, to write her own reflection on the topic.
In her speech, Jiang encourages people to listen to one another without judgment, looking for shared beliefs rather than conflict.
“If we still believe in a shared future,” she writes, “let’s not forget: Those we label as enemies, they, too, are human. In seeing their humanity, we find our own.”
Photo by Grace DuVal
‘De Haereditatibus Peregrinis (On Foreign Inheritances)’
Aidan Scully
When your father is a high-school Latin teacher, “The Aeneid for Boys and Girls” is bedtime story material. At least, that was the case for Scully.
“The story was not in Latin,” he clarified, “but I had ancient history stories floating around from pretty early on.”
When it came time to choose a language at nearby Taunton High School, he remembers his father joking that he was allowed to study whichever one he wanted — as long as it was Latin.
Fortunately, Scully loved it.
“From day one,” he said, “I was hooked.” He took every Latin class the school offered, and when he was done, he continued independent study courses with his Latin teacher, Jessica Ouellette.
With her support, he worked toward publishing a translation of the first poem in Ovid’s “Amores,” from 16 B.C. Though others had translated the text before, he wanted to preserve its original metric playfulness.
“You can read Latin, and it can be an intellectual thing,” he said. “But I think trying to make poetry accessible to people in the way that it would have been 2,000 years ago bridges history in a way that is really exciting.”
Scully, a resident of Adams House, planned to concentrate in classics and government but realized his interests better aligned with a joint concentration in classics and religion. From sophomore year on, he split the bulk of his academic work studying the relationship between politics and religion in the ancient world and how they shape the modern U.S.
His former area of interest led to his thesis about how Romans in Late Antiquity balanced their Roman and Christian identities. While most people accept today that one can embrace both a religious and national identity, many Romans found this inconceivable.
“People at this time are trying to make sense of the fact of, ‘Well, if I am Roman and I am Christian, what does that mean? How are the two different? How do I make sense of the parts where it doesn’t seem like I can be both?’”
He found those fundamental questions relevant to the modern relationship between religion and government in the U.S. While mainstream U.S. history highlights religion’s impact on certain eras — The Great Awakening, the Civil Rights Movement — Scully studied its persistent presence over time.
Learning about evangelicalism and the landscape of Protestantism in the U.S. while studying ancient analogues fascinated Scully.
“This is the intersection I want to work at,” he said, “seeing what comparisons I can draw that maybe people haven’t thought to put in the conversation.”
His studies also affected how Scully approached his own faith and community service.
“Every work of religious scholarship begins with something like, ‘We don’t really know what religion is,’” Scully said, smiling. “It’s not easy to provide a definition that isn’t just a list of examples.” He finds that lack of certainty — and expansive approach — helpful in his volunteer work with queer interfaith communities.
“The lines we’re drawing are almost always arbitrary and usually based on at least one misconception,” he said. “Thinking critically about that leads to more inclusive activism.”
Besides introducing Scully to age-appropriate epics in childhood, Scully’s father, Christopher, also provided an example to Scully in a different way: He was Harvard’s Latin Orator in 1994. Family legend has it that his grandmother showed up not knowing that his father was about to deliver a Commencement address.
This time, though, Scully’s parents will know. He credits his mother, who graduated from Harvard as Elisa Leone in 1996 with a degree in social anthropology, for holding him accountable to reach the goals he set for education, and his life.
“I’ve been truly extremely fortunate to have a family that’s been so supportive of me doing a thing that’s kind of obscure and not, you know, employable,” he said. “The fact that things seem to be working out so far is a testament to them.”
Veasey Conway/Harvard Staff Photographer
‘This World is Not Conclusion’
Thor Reimann
Reimann was born and raised in Apple Valley, Minnesota, with parents who encouraged him and his two older siblings to pursue their own interests. It took each on a different path: His sister is a nurse; his brother is a nuclear submarine officer with the U.S. Navy; and Reimann hopes to attend law school and practice environmental law.
As a first-year, though, Reimann’s vision wasn’t quite so clear. In high school, he said, “I loved every subject.” He trusted that he’d find his way to a fulfilling academic experience and, as one of the only openly queer students from his high school, “the personal space to fully explore who I was,” he writes in his English Oration.
At first, Reimann, a resident of Mather House, thought he might concentrate in history and literature or social studies, which would allow him to take a broad range of classes. A general education course he took freshman year shifted his trajectory: “Life and Death in the Anthropocene.”
The course, taught by Naomi Oreskes, Henry Charles Lea Professor of the History of Science, encouraged Reimann to think about climate change and environmental problems from a range of academic and personal perspectives.
“They really touch every aspect of human life that’s out there,” he said. “I found myself constantly thinking about it when I would leave class.”
A lover of nature who would go on to join the steering committee for the First-Year Outdoors Program, Reimann decided to pursue a joint concentration in environmental science and public policy and comparative religion. Though he appreciated the technocratic element of environmental studies, the added focus on religion helped him balance policy with a big-picture idea of what he was trying to protect in the first place.
With guidance from Terry Tempest Williams, the Harvard Divinity School writer-in-residence, Reimann developed a deep interest in conservation. His joint major, and his conservation interest, sparked his senior thesis on Bears Ears National Monument, a federally protected area in southeastern Utah.
One of the most culturally dense landscapes in the U.S., the federal monument contains artifacts from different Native American tribes dating back thousands of years. Reimann was interested in how political organizing across different tribes that described the area as “sacred” helped earn it federal protection in 2016 — and how the same idea of “sacredness” was used by different groups to reduce its size the following year.
“The government just doesn’t have the right policy tools to be able to create space to talk about these claims,” he said.
Just as his thesis can be traced to first-year discoveries, so too can his speech. The title, “This World is Not Conclusion,” is borrowed from an Emily Dickinson poem that he read during a first-year seminar.
“I was having this big moment of, ‘Oh gosh, what am I going to do? How do I think about this opportunity?’” said Reimann. “And I think a lot of the poem is about how the circumstances of the day that you’re in right now are going to change. There’s going to be something that comes next.”
He felt especially struck by the final two lines of the poem: “Narcotics cannot still the Tooth / That nibbles at the soul —”
“You can have a lot of money or you can have a lot of power,” Reimann said, “but still, the tooth is going to nibble — so you better listen.”
The poem helped him be comfortable letting his curiosities guide him as he started his undergraduate experience. It also helped him process its conclusion.
“In this time when there’s a lot of uncertainty and fear, I think it can be reassuring that there is something coming next, and we have the agency to go and be a part of creating that,” he said. “It’s not just an end. New things are beginning.”
Campus & Community
Federal funding freeze leaves grad students, postdocs scrambling for labs, support
“Recently one of the best funders of spinal cord injury research … had its funding cut. It was about $40 million, a third of all spinal cord injury funding,” said Jason Biundo, a first-year doctoral student.Photos by Niles Singer/Harvard Staff Photographer
Sy Boles
Harvard Staff Writer
May 27, 2025
5 min re
Federal funding freeze leaves grad students, postdocs scrambling for labs, support
“Recently one of the best funders of spinal cord injury research … had its funding cut. It was about $40 million, a third of all spinal cord injury funding,” said Jason Biundo, a first-year doctoral student.
Photos by Niles Singer/Harvard Staff Photographer
Sy Boles
Harvard Staff Writer
5 min read
Pipeline of up-and-coming researchers an integral part of nation’s innovation ecosystem
First-year Ph.D. students at the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences studying in Harvard Medical School’s Biological and Biomedical Sciences Program are facing an unprecedented challenge as they begin a process that will soon lead to one of the most consequential decisions in their careers: finding the right lab and mentor for their research.
“I’m supposed to be choosing labs, but all of the labs I’m talking to and rotating in, they have no idea what the funding situation is, if they can take students, if they have money for our salaries or the projects we want to do,” said Jason Biundo, a first-year doctoral student. “It feels disappointing.”
The University has been buffeted in recent weeks by a series of Trump administration moves to halt or cut federal research funds, beginning on April 15 when the administration announced it would freeze $2.2 billion in grants. In response, Harvard has filed suit, arguing the government’s actions and demands violate federal law and the University’s First Amendment rights.
Harvard is not the only institution of higher education in the nation losing federal research funds. The administration has targeted at least two dozen others and made at least $11 billion in cuts. Scientists say the losses threaten to upend the government-higher education partnership that has led to medical breakthroughs that saved millions of lives and launched numerous companies in the post-war period.
An integral part of that innovation ecosystem involves ensuring a steady pipeline of up-and-coming researchers.
Graduate students are “the engines in our labs that are generating all these new ideas and all this data,” said Beth Stevens, associate professor of neurology at Harvard Medical School. “Their salaries are covered by federal funds. It’s so fundamentally important: the ability to recruit amazing talent, keep amazing talent, and then support them in the next phases of their careers where they’re going to apply for grants. It’s the way we do it.”
Ph.D. students doing work in the Biological and Biomedical Sciences (BBS) program typically spend their first year rotating between labs, both “auditioning” for long-term research positions and doing their own assessments: Is it a good cultural fit? Would the principal investigator be a good mentor for their personality and career goals? Would they be able to do the kind of research they’re passionate about? By the third year of the program, students’ salaries should be covered by a combination of their own federal grants and work they do to assist their PIs on the PIs’ grants.
Biundo plans to study spinal cord injuries, a topic that’s deeply personal to him: When he was an undergraduate at the University of Massachusetts Amherst, he suffered a serious spinal cord injury that left him partially paralyzed.
“Recently one of the best funders of spinal cord injury research, the Department of Defense’s [Congressionally Directed Medical Research Programs], had its funding cut. It was about $40 million, a third of all spinal cord injury funding,” Biundo said. “I think it was already an underfunded condition to begin with, with such a large patient population, and to see that is really disheartening for the future of spinal cord research.”
Postdoc Cherish Taylor fears her funding will be terminated at the end of the current funding cycle because the program falls under the umbrella of diversity, equity, and inclusion programming.
Cherish Taylor.
The funding uncertainty isn’t just impacting doctoral candidates. Cherish Taylor, a postdoctoral researcher studying environmental risk factors for the onset, progression, and severity of psychiatric disorders, has been funded by the NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience Award (D-SPAN). The program supported graduate students and postdoctoral scholars from diverse backgrounds, including groups that have been under-represented in neuroscience.
“People of color, even to some extent women, but less so nowadays, and certainly people in the LGBTQ community, we are minorities within the STEM field. You may be the only person that looks like you in your program, in your department. Having this type of grant program is nice for remembering that you aren’t actually the only person who looks like you in the field.”
Taylor fears her funding will be terminated at the end of the current funding cycle because the program falls under the umbrella of diversity, equity, and inclusion programming, which has been a target of the current administration.
“My PI has repeatedly assured me that she will do whatever she can to provide funding for me,” Taylor said. “But it still doesn’t remove that emotional burden of knowing your peers are not in the same place, people you know and care about and want the best for.”
Harvard President Alan Garber announced on May 14 that the University is dedicating $250 million of central funding to support research affected by suspensions and cancellations.
“We stand behind our thousands of outstanding faculty, postdoctoral, staff, and student researchers,” Garber said. “Together they continue to make revolutionary discoveries, cure illness, deepen our understanding of the world, and translate that understanding into impact and invaluable teaching and mentorship that will produce the next generation of leading scientists and innovators. It is crucial for this country, the economy, and humankind that this work continues.”
Some labs may be able to support junior researchers through philanthropic funding, industry partnerships, or operational adjustments. But uncertainty remains.
“At the beginning of the year, things felt like, you’re starting a new Ph.D. program, and you have a very bright future ahead,” said Biundo. “And then you’re hit with the uncertainty of this career path as a whole.”
Rupen Dajee. Veasey Conway/Harvard Staff Photographer
Campus & Community
Frustrated fighting wildfires in L.A., he resolved to build better tools
Christina Pazzanese
Harvard Staff Writer
May 27, 2025
4 min read
Rupen Dajee launches tech startup to aid emergency responders, leveraging lessons learned firsthand as EMT, firefighter
Part of the
Commencement 2025
A collection of features and profiles covering Harvard University’s 374th Commencement.
Had it not been for wildfires, Rupen Dajee may never have gone to graduate school.
They’re a seasonal occurrence in his home state of California, where he was a firefighter-paramedic before coming to Harvard Kennedy School and MIT’s Sloan School of Management to complete a dual M.P.A./M.B.A. degree program. He’ll graduate from the Kennedy School this week.
After college, Dajee became a licensed emergency medical technician working on an ambulance in Los Angeles in the area once known as South Central. What started out as a rewarding side job became a passion. So he went to paramedic school and trained as a firefighter, joining a small rural fire department in the mountains outside of the city.
There, Dajee experienced the technology inequities that rural emergency responders like firefighters have to overcome just to do what is already a difficult job.
“I would get sent out to wildfires during the summers and experience communications issues,” he said. “It’s a really tough technological environment to operate within and so, I thought, ‘What can I do to help with that?’”
“I would get sent out to wildfires during the summers and experience communications issues. It’s a really tough technological environment to operate within and so, I thought, ‘What can I do to help with that?'”
Dajee started a technology venture called Twisted Kelp that develops tools to help solve some of the field challenges facing wildland firefighting, emergency services, and disaster management.
The infrastructure that enables emergency communications to work can fail under harsh conditions or may be insufficient for the vast expanses and difficult rural terrain, forcing firefighters to make some tough calls.
“You need to start thinking, ‘Do we send people down there, do we not because we’re not able to support adequate communications? Is that a vital area we still have to send people into even if we can’t cover it?’ There can be gaps in areas of opportunity where technology can help to solve those problems, to enable greater capabilities.”
The company produces satellite tracking and communications solutions with an online interface that overlays fire maps and infrared data so firefighters can see where personnel and equipment are positioned or needed. Another product enables emergency radio service using Internet Protocol packets. The company also developed a digitized version of a pocket-size booklet called the Incident Response Pocket Guide that firefighters often carry on them to reference instructions on the fly for an array of scenarios.
Because technology advances for the public sector are often longer-cycle and can affect a much broader scale than the private sector, Dajee said he realized it would take more than an M.B.A. to make his company truly effective. The focus on leadership and problem-solving on a grand scale at the Kennedy School and Sloan’s emphasis on principled business innovation were motivating, he said.
“Leadership and management shouldn’t just be about gross revenue maximization,” Dajee said. “It’s about the people, their context, and the environment,” as well as “trying to push the boundaries of what’s possible and what good that you can bring into the world with business.”
“It’s about the people, their context, and the environment.”
After Commencement, Dajee will return to L.A., where he spent three weeks in January fighting the devastating wildfire in the Pacific Palisades, an area he had lived near for many years.
“I knew almost every street where the fires were burning and had driven up and down those streets for a better part of 10 years,” said Dajee. “It was very surreal seeing these places that I knew, these homes that I had passed by many times and recognized, burned to the ground.”
Dajee said he’s immensely grateful to have had an opportunity to study at Harvard and MIT when so few of his colleagues in emergency services have chosen to attend graduate school. Most have a “deep passion” for what they do but struggle with systemic issues facing emergency healthcare and rural emergency services in the U.S., he said.
“It’s important that the work they do is recognized because they put their lives on the line on a daily basis in the harshest conditions to keep others safe, with long-term consequences that are often unsupported,” he said. “And while it is great that everyone thanks their first responders when they have a need for them, it is also important to remember that the work continues in the background even when they don’t.”
Harvard Yard. Photo by Dylan Goodman
Campus & Community
12 alumni elected to Harvard leadership boards
New Overseers and HAA directors to begin terms in May, July
May 27, 2025
4 min read
Six alumni have been newly elected as members of Harvard University’s Board of Overseers, with another six joining the board of directors of the Harvard Alumni Association (HAA). The new Overseers will assume their r
New Overseers and HAA directors to begin terms in May, July
4 min read
Six alumni have been newly elected as members of Harvard University’s Board of Overseers, with another six joining the board of directors of the Harvard Alumni Association (HAA). The new Overseers will assume their roles on May 30, while the HAA directors will begin their terms on July 1. Five of the new Overseers were elected for six-year terms. The sixth, Anjali Sud, will serve the remaining two years of the unexpired term of Mark Carney.
New members of the Board of Overseers
Mark A. Edwards’82, cum laude Co-founder and CEO, Upstream USA; founder and former executive director, Opportunity Nation Brookline, Massachusetts
Mary Louise Kelly ’93, magna cum laude M.Phil. ’95, University of Cambridge, with distinction Journalist and broadcaster, co-host of “All Things Considered,” NPR Washington, D.C.
Nathaniel Owen Keohane, Ph.D. ’01 B.A. ’93, Yale University, magna cum laude President, Center for Climate and Energy Solutions New York
Michael Rosenblatt, M.D. ’73, magna cum laude B.A. ’69, summa cum laude, Columbia University Advisory partner, Ascenta Capital; senior adviser, Bain Capital Life Sciences and Flagship Pioneering; former executive vice president and chief medical officer, Merck & Co.; former dean, Tufts University School of Medicine Newton, Massachusetts
Anjali Sud, M.B.A. ’11 (filling Carney’s unexpired term) B.S. ’05, University of Pennsylvania CEO, Tubi; former CEO, Vimeo New York
Courtney B. Vance ’82 M.F.A. ’86, Yale University Actor, producer, writer; president and chair, SAG-AFTRA Foundation La Cañada Flintridge, California
A group of seven candidates for the Board of Overseers were nominated by an alumni nominating committee whose 13 voting members are appointed by the Harvard Alumni Association executive committee. An eighth candidate withdrew from consideration. Harvard degree holders cast a total of 39,725 ballots in the election.
The Board of Overseers is one of Harvard’s two governing boards, along with the President and Fellows, also known as the Corporation. Formally established in 1642, the board plays an integral role in the governance of the University, complementing the Corporation’s work as Harvard’s principal fiduciary board. As a central part of its work, the board directs the visitation process, the primary means for periodic external assessment of Harvard’s Schools and departments. Through its array of standing committees, and the roughly 50 visiting committees that report to them, the board probes the quality of Harvard’s programs and assures that the University remains true to its charter as a place of learning. More generally, drawing on its members’ diverse experience and expertise, the board provides counsel to the University’s leadership on priorities, plans, and strategic initiatives. The board also has the power of consent to certain actions, such as the election of Corporation members. Additional information about the board, its members, and its work can be found on its webpage.
Newly elected HAA directors
Theresa J. Chung ’98, magna cum laude, J.D. ’02 Administrative judge, U.S. Merit Systems Protection Board Dallas, Texas
Colin J. Kegler ’97 Senior software engineer, HealthEdge Inc. Provincetown, Massachusetts
Victoria “Vicky” Wai Ka Leung ’91, cum laude M.B.A. ’98, New York University Managing director and consultant, EC M&A London
Nicholas J. Melvoin ’08 M.A. ’10, Loyola Marymount University; J.D. ’14, New York University Elected board member, Los Angeles Unified School District Los Angeles
Angela M. Ruggiero ’02, cum laude, M.B.A. ’14 M.Ed. ’10, University of Minnesota Co-founder and chair, Sports Innovation Lab Weston, Massachusetts
Sanjay Seth, M.P.A. ’19, M.U.P. ’19 B.A. ’12, Goldsmiths, University of London Former chief of staff and senior adviser for climate and equity, U.S. EPA New England East Boston, Massachusetts
The new directors were elected for three-year terms. They were chosen from among nine candidates, nominated by the same HAA committee that puts forward candidates for Overseers. Harvard degree holders cast 41,069 ballots in the directors election.
The HAA board, including its elected directors, is an advisory board that aims to foster a sense of community, engagement, and University citizenship among Harvard alumni around the world. The work focuses on developing volunteer leadership and increasing and deepening alumni engagement through an array of programs that support alumni communities worldwide. In recent years, the board’s priorities have included strengthening outreach to recent graduates and graduate school alumni and continuing to build and promote inclusive communities.
Campus & Community
Upholding the mission in a year of turmoil
Harvard President Alan Garber. Stephanie Mitchell/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
May 27, 2025
long read
Garber greets Commencement with high hopes for students and a strong affirmation of University’s contributions to U.S. growth, health
As grades were being calculated and the Yard was being t
Garber greets Commencement with high hopes for students and a strong affirmation of University’s contributions to U.S. growth, health
As grades were being calculated and the Yard was being transformed into a stage for Commencement, President Alan Garber sat down with the Gazette to reflect on the challenges of a turbulent year and the promise of graduation day.
This interview has been edited for clarity and length.
Students are preparing to graduate in what is always one of the most celebratory and hopeful weeks of the year. You received an economics degree from Harvard College in 1976. Do you remember your state of mind that day — whether you felt a sense of purpose?
At the time, I probably would have told you that I did. I had already decided to pursue both a Ph.D. in economics and an M.D. I was certainly excited about learning economics at a deeper level and becoming a physician. But I had only a vague idea of what would come after I completed my formal studies.
What I did have was a sense that I would be well-equipped to grapple with important health policy issues, with a program of study that was unusual at the time. Above all else, I felt grateful to my fellow students from whom I learned so much, toward the faculty who worked with me, advised me, and inspired me, and toward the institution as a whole for giving me a chance to become part of a great community.
Combining economics and medicine would likely never have occurred to me had I gone to college elsewhere. My path was probably set when I took Ec10, which was nearly a universal course at the time — about three-quarters of Harvard undergrads took it. If not for that, I might have become a doctor of a different kind.
Harvard and higher education have been caught up in a deeply politicized environment, and we’ve seen the federal government cut research funding and launch investigations into institutions. What do you say to members of the community concerned about the University’s future?
We should all be concerned that colleges and universities have increasingly come under attack. But we should not dismiss the criticisms even when they are based on distortions or inaccuracies — we need to look for the underlying concerns that can be embedded in them. For example, many members of our community have been alarmed that students have become increasingly reluctant to speak openly about controversial or uncomfortable topics, especially if they believe their personal views are unpopular. That’s a problem we need to solve, and over the past year and a half we’ve done a great deal to address it. Many of those efforts are described in the report of the working group on open inquiry and constructive dialogue.
Still, we believe that the government overreach and devastating attacks on scientific and medical research are unwarranted and unlawful, and so we have taken legal action to defend the institution.
There are also concerns about the cost of higher education and the value it offers students. In fact, the actual cost of attending Harvard College is much lower than people may think. We offer generous financial aid, so, for most Americans, it would cost less to attend Harvard than a state university. The actual cost of attendance for the average student receiving financial aid — more than half of all undergraduates — is roughly $13,000. And starting with this year’s entering class, Harvard will be tuition-free for children from families earning less than $200,000 per year.
We need to ensure that the public has a better understanding not only of the affordability of the education we offer, but also of the benefits we provide to our students and the public at large. We’re a research university, always striving to expand the boundaries of knowledge. That has large and very tangible benefits for our country, often manifested in contributions to economic growth and to better health. When we look ahead, I am confident that the value of research universities will continue to be widely recognized and that we will be successful for the long term, despite the challenges we’re facing today.
Last week, the University secured a temporary restraining order blocking the federal government from removing F and J visas from Harvard students starting next academic year. Can you talk about the University’s quick response and what’s next?
We needed to move quickly because the consequences of revocation of visas for our international students were dire. These are students who are following their dreams at Harvard. Their contributions to our community are deep and extensive; they bring with them their expertise and insight as well as unique perspectives and experiences, which they share in the classroom, in residences, and everywhere that students can be found. We are doing all we can to ensure that these and future students can successfully pursue their studies at Harvard.
There will be a hearing in court later this week where we will argue that the restraining order should be extended. And even though we were successful last week, we recognize that there will continue to be many questions and concerns. The Harvard International Office is working closely with our international students to help.
How might the unsettled environment for students affect learning? Are there important lessons even in times of conflict?
Learning often advances most rapidly during times of conflict. We gain a new understanding of our strengths and weaknesses. We often learn that we can do what we didn’t think was possible.
As we think about impediments to open dialogue and how we’ve addressed them, I believe that students who are graduating now have gained a deeper understanding of what it means to truly listen to, and speak with, another person. I hope that our students — indeed every member of our community — will have learned that forming close relationships, especially with people who are different from us, is intensely rewarding. Along the way, we will develop greater empathy and learn valuable lessons.
What challenges and opportunities do you see for graduates? It seems safe to say that artificial intelligence counts as both, in significant ways.
It’s too soon to predict how AI will change the lives and careers of graduating students, but knowing how to work with AI is already advantageous in some areas of work and essentially a requirement in others. With the rapid progress in generative AI, we’re seeing that specific skills in its use — say, prompt engineering — can become less important as the technology evolves.
I expect that, overall, the people who will thrive in the economy of the future are those who are adept at using technological tools well. But who will those people be? We have people working on scientific problems whose expertise is in AI, and others whose expertise is in a specific area of science, and many whose expertise is a blend of each. What will be the best mix? We’ll be learning this in many domains of application in the coming years.
I count myself among those who think that basic human skills — empathy, compassion, and interest in other people — will be more important than ever as the reach of AI expands.
How do you balance the demands of hard, time-consuming problems versus those that require a quick decision?
You don’t usually have a choice — you need to deal with both. But even when there are quick decisions to be made, we should always think about long-term consequences. As we approach our 400th anniversary as an institution, we continue to benefit from far-sighted decisions of our predecessors. A long-term perspective enables us to make investments today whose payoffs will be long-delayed but consequential — even transformative. That is the fundamental premise of basic science research, for example, but it applies far more broadly.
You recently announced that the University will dedicate $250 million to support research at the Schools. What can that money do and what can it not do?
The support that we’re providing is intended to facilitate the continuity of our research efforts. It is meant to ensure that we can maintain a strong base of research and minimize the disruption of the research enterprise that comes from the federal denial of research funding. It cannot sustain our research operations for the long term, so we are taking a close look at ways to further lower the costs of conducting research and to diversify the sources of funding. However, the research advances at Harvard and other universities that have led to the scientific pre-eminence of the United States would not have been possible without federal research support. The partnership between universities and the federal government is important for this country’s future scientific accomplishments, not only at Harvard but also at other universities throughout the nation.
When we talk about lowering the cost of research, is that seen as a way to get through a difficult time or might there be changes that spark innovation and lower costs over the long term?
The latter. Our efforts to improve the efficiency of the scientific enterprise may be more intense at a time of financial stress, but we should always look for ways to do more with less money. This won’t be easy. Some of the most important scientific advances are inherently expensive. For example, we’ve made investments in cryo-electron microscopy, a recently developed technology that requires large capital investments but has led to extraordinary scientific advances. Expensive tools, used appropriately, can find answers more quickly and less expensively than the approaches they replace. To keep costs down often means that we need to invest wisely, which sometimes means making a smaller number of large but strategic investments. Our researchers are creative and ingenious. I am confident that they will find new ways to do truly cutting-edge research more efficiently.
Is the endowment being considered as an additional funding source?
The endowment already supports the operating budgets of our Schools, much of it directed toward research activities. About 80 percent of the endowment is subject to restrictions: We can’t use money intended to support a professor of economics, for example, to fund scientists in a molecular biology lab. So, although it’s a critical asset, the endowment — and ours consists of roughly 14,000 endowment funds — can’t be used as a general-purpose fund or, as some people say, as a rainy-day account. In addition, an endowment is intended to be available in perpetuity. Recognizing those constraints, the endowment certainly can be helpful.
If there were to be declines in the value of the endowment — if, for example, the large endowment tax in the House budget bill were passed into law — it would affect all of these activities. The impact would be particularly severe for financial aid, which is heavily supported by endowment funds.
With regard to antisemitism and other forms of bias, how sure are you that the steps Harvard is taking will alter the campus environment?
We’re building on work that we have undertaken over the course of the last year and a half, along with the recently released final recommendations of the two task forces. The Schools and the University are working on implementation of those recommendations. It’s worth reviewing the recommendations to appreciate their scope — they apply to many different aspects of University life.
Some of the interventions we’ve undertaken or planned are quite specifically targeted to improve the lives of Jewish students. Others are intended to educate the University community. The latter areas include orientation programs, training of faculty, and the addition of new courses that relate to the topics of antisemitism and the history of the Middle East. But much of what we are doing involves changing attitudes toward one another, facilitating constructive speech and constructive disagreement, and building bridges across different identities and student groups. It’s a multifaceted strategy intended to change culture on campus.
If that strategy is fully successful, we will have made vital progress in tackling hate and bias, and it will prevent the shunning and other forms of social exclusion reported by Jewish and Israeli students; by Muslim, Arab and Palestinian students; and by other members of our community. There can be no place for hate at Harvard.
As to the effectiveness of the actions we’re undertaking, it may be too early to tell. But reports of a more open and less tense campus atmosphere throughout the academic year that is now ending give me hope that even our early efforts are bearing fruit.
Although we know that Harvard alone will not end antisemitism — it has been a stain on humanity for more than 2,000 years and is pervasive in the world — we need to do all we can to address it with resolve and with humility, knowing that it will require sustained effort.
Similarly, we need to pursue educational approaches, make accommodations for the practice of religion, and build empathy. We have heard a similar set of stories about how Muslim or Palestinian students often feel unwelcome and isolated. Our programs regarding speech and building bridges across differences are designed to help with all forms of hate and discrimination.
That would align with steps the University is taking to encourage viewpoint diversity and constructive disagreement?
Yes, these are mutually reinforcing efforts. We want to ensure that our students are exposed to diverse perspectives on the issues that we study, discuss, and research. We often hear complaints that universities like ours have a political monoculture, because politically our faculty and students skew to the left when compared to Americans overall. This means that there is at least a risk — particularly in the social sciences and humanities — that our community will not be exposed to the full range of ideas that should be discussed and debated. Furthermore, people who hold minority views on campus may feel uncomfortable expressing them. Surveys generally confirm these impressions.
Part of the challenge is to ensure that people who bring more diverse views will feel welcome on our campus and free to express their views. We are developing plans to bring respected, rigorous, and compelling voices to campus, including tenured faculty, who will expand our intellectual horizons and bring new insights into many fields, such as those related to policy, government, and law.
An immediate challenge is to nurture an environment of openness and mutual respect that will encourage people who fear that their views are unpopular to feel comfortable expressing them. So, what must we do as an institution to ensure those views can be heard?
This is where our efforts to promote open discourse and constructive dialogue should make a difference. It’s important for faculty to model this behavior in the classroom and create an atmosphere where students feel comfortable expressing views that others may not agree with. We’ve begun that work and will continue to build on it.
It is obviously not a secular university’s role to dictate a set of values, but do you think Harvard students leave campus with a stronger foundation for developing their own?
Encouraging thinking about values is pervasive in the University. It’s in the obvious places, like philosophy and the Divinity School, but it’s also a prominent topic in the Business School. It’s in the humanities in general. Almost all great literature presents situations that provoke thinking about what constitutes ethical behavior, why people knowingly commit wrongs, and the consequences of failing to act according to one’s values.
I doubt that any Harvard College student can graduate without having to grapple with questions about values. Judging from the enrollments in Michael Sandel’s “Justice” course, they don’t want to miss the opportunity. As in so much else, we want to help our students learn how to think about values and how to act on them, but that doesn’t mean that we should tell them which values they should adopt. Except “veritas.” I hope that every graduate embraces the importance of truth and chooses to live by it.
Nation & World
Let’s not send low-income students back to the ’80s
Niles Singer/Harvard Staff Photographer
Max Larkin
Harvard Staff Writer
May 23, 2025
5 min read
Financial aid red tape nearly derailed Susan Dynarski’s undergrad dreams. Now she sees decades of progress under threat.
Part of the
Profiles of Progress
series
Back in the early
Back in the early 1980s, a few pages of incomplete paperwork were casting a shadow over Susan Dynarski’s future as a Harvard undergraduate.
“My parents got divorced,” Dynarski recalled. “And when I turned 18, my dad refused to fill out the financial aid forms any longer — he said he wasn’t responsible for me since I had come of age.”
That left Dynarski to pay tuition without grants that reflected her true financial need. Her single mother took a few risks — opening new loans, taking a mortgage on their Somerville home — and Dynarski earned her A.B. in social studies in 1987.
Forty years on, Dynarski is now at the Harvard Graduate School of Education, at the front of a wave of scholars working at the intersection of economics and education.
It’s a very different moment. There are well-maintained federal databases tracking how and why students from all backgrounds enroll in college and how they fare once there. And while tuition is markedly more expensive, financial aid is more generous, and administrators are more attuned to the special challenges confronting first-generation college students.
Even still, low-income students — even with sterling academic qualifications — tend to enroll at the nation’s top schools at far lower rates than peers who are similarly qualified.
Dynarski remembers being cash-strapped on campus. But her recent work has focused less on the amount of money available than the process for securing it.
“It’s not that people can’t fill out forms,” Dynarski said. “You could figure it out, but it’s a time cost. And then the whole structure of the financial aid process delays knowing about your eligibility until after you’ve applied, been accepted, and gotten an offer from an institution — it backloads all of that information.”
Starting in 2015, Dynarski proposed an alternative. Along with several colleagues at the University of Michigan at Ann Arbor, that state’s most selective university, she launched what came to be called the HAIL scholarship program.
Dynarski’s team identified young people who had both the academic credentials to have a chance of admission to the Michigan flagship, and the economic circumstances to attend for free if they enrolled.
The HAIL trial aimed, simply, to let those students know that fact.
In the fall of their senior year, eligible students in the “treatment group” were sent colorful, celebratory packages, including what Dynarski and co-authors call “an early, unconditional guarantee of tuition” for four years. (Their parents and school principals received similar messages.)
The effects were remarkable. Nearly 70 percent of eligible students who received HAIL notices applied to Michigan, compared to 26 percent of those who didn’t. Almost half of those who applied were accepted — much higher than the university’s acceptance rate for all applicants. And 27 percent went on to enroll.
The effects extended to selective schools elsewhere, too. And, perhaps most impressive, those effects were achieved without offering new aid.
“The intervention did not change costs for these students: Rather, it offered an early guarantee of grants for which, in expectation, they were already eligible,” Dynarski and her coauthors noted in a 2018 paper.
It’s a kind of “nudge,” a simple intervention that improves a complex system: simplifying bureaucracy, growing lifetime earnings, and expanding the well-trained workforce.
With that and other findings, Dynarski has marshaled high-level economics to work in the public interest.
“I was always in this, not because I’m into testing economic theories, but because I wanted to make the world better — to advance economic mobility,” she said, pointing out that she was a union organizer for six years before her academic career fully took shape.
And her career, in turn, is almost unthinkable without public support.
In study after study, Dynarski has relied on large, longitudinal datasets that only the federal government could maintain. And she has received millions in research support from the Institute for Education Sciences (IES), the research arm of the U.S. Department of Education. The HAIL program, for instance, would have been much more difficult without federal grants that allowed her to set up a longitudinal data system still running in Michigan.
Just a few years after coming to Harvard, an ongoing symbiosis is now in considerable doubt.
Dynarski has a grant request outstanding with the IES, and — amid the escalating funding fight between Harvard and the Trump administration — assumes it’s dead.
Meanwhile, cuts proposed by the Department of Government Efficiency, or DOGE, aim to shrink the IES from 100 employees to just three, meaning a near-total elimination of the datasets on which she her built her career.
Dynarski said such a cut could imperil the booming subfield of education economics — closing a window on the progress of American lives and catapulting the country back to where it was when she was a teenager, and families like hers were struggling in obscurity.
“I feel like this administration has attacked just about everything I’ve been working for,” Dynarski said. In the worst-case scenario, she adds, “It’s not just that low-income people won’t be able to get jobs as scientists — there won’t be American science.”
But she’s not yet discouraged. “You just pick where you can make a difference. I advise students. We still have state governments, local governments — I put my hope into them.”
And, just last month, she joined a lawsuit filed by the National Academy of Education against the Department of Education, aiming to block the planned cuts.
Lindsey Chrismon. Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
After flying Apaches, she needed a new challenge
Lindsey Chrismon sets sights high from West Point to Harvard Business School
Anna Lamb
Harvard Staff Writer
May 23, 2025
5 min read
Part of the
Commencement 2025
series
A collection of features and profiles
A collection of features and profiles covering Harvard University’s 374th Commencement.
Lindsey Chrismon wasn’t satisfied just getting into West Point, the country’s top military college, for her undergraduate degree. She would go on to be selected as the First Captain, the top cadet, in her graduating class of 2014, only the fourth woman to hold the position in the academy’s more than 200-year history.
After graduation, she wasn’t going to hold just any military position — she would fly the top attack helicopter, the Apache, as part of the most elite force in the sky. And when it came time to move on from her military career, she wouldn’t go to just any business school for her MBA. She would go to Harvard.
“I actually wrote in my West Point yearbook that I wanted to go to Harvard Business School 10 years ago,” Chrismon said.
Chrismon is the type to set a goal and make it come true. Becoming a helicopter pilot, for example, was a goal she set in her first year at the academy.
“I remember sitting in my room and an Apache helicopter came down and landed on the parade field, right outside,” she said. “I was like, I want to fly that … it was just a dream from the first moment I saw it.”
Photo courtesy of Lindsey Chrismon
She got the grades, scored well on the necessary tests, and after graduation became the first woman in Army history to fly the AH-6 Little Bird helicopter for the 160th Special Operations Aviation Regiment.
“It’s the same unit that flew the SEALs into the Osama bin Laden raid,” Chrismon said. “It’s the most elite helicopter force on the planet, honestly.”
After flying Little Birds, and then her dream Apaches for almost 10 years, Chrismon started to get, for lack of a better word, bored. It was time for a new venture.
“Every single day was actually pretty great. It didn’t feel like work in that regard, but I did feel at a certain point intellectually capped,” she said. “I also saw where I would be in, say, three years, and I didn’t really want to have my future completely laid out for me. I wanted to experiment and get out in the world and do other things and face different challenges.”
Her husband, Gabe Chrismon, said his wife, who was his West Point classmate, “has never chosen the easy route.”
“HBS was where she was going to go no matter what.”
He added, “If Linds has an idea of what she wants to do, she’s pretty much going to find a way to make sure that happens. And then she’s going to find a way to succeed and be one of the better ones at it — from West Point being the First Captain, to flying Apaches, to flying Little Birds, to going to HBS, to being a female founder and raising money.”
The Chrismons are not just life partners, they’re business partners. They co-founded Oply — an AI-powered tool to help homeowners manage their home systems and maintenance.
Chrismon has spent much of the last year at Harvard raising capital for the company, and many of the last year’s weekends flying to her home city of Nashville to get the business up and running.
“Sometimes she’d get beaten up, and she would just continue fighting back. This is a real mark of a founder, which is, yes, you take the advice, but you’ve thought about this problem a lot more than the person you’re talking to and so you don’t wither, you fight back.”
Reza Satchu
“I’ve cold-called her to present her business to very-high-profile investors in my classroom without her knowing it was coming,” said Reza Satchu, senior lecturer in the Entrepreneurship Management Unit at the Business School. “Everyone from senior decision-makers at venture capital firms, to the CEO of Delta, to Kevin O’Leary, to all sorts of people.”
Classes that Chrismon took with Satchu, “Founder Mindset” and “Founder Launch,” both specialize in getting student enterprises up and running.
“She has an ability to just stand up and deliver a compelling value proposition with real conviction around her business,” Satchu added. “Sometimes she’d get beaten up, and she would just continue fighting back. This is a real mark of a founder, which is, yes, you take the advice, but you’ve thought about this problem a lot more than the person you’re talking to and so you don’t wither, you fight back.”
While Chrismon is excited to get back to her life in Nashville, she’s sorry to be leaving the Business School.
“It went really, really fast,” she said. “It’s bittersweet that it’s over. It’s wonderful because then I can focus solely on our venture, but not waking up every day and going to class with my friends — that’s going to be sad to leave behind.”
Harvard file photo
Campus & Community
Marine vet’s future was a puzzle. Then he found archaeology.
Christy DeSmith
Harvard Staff Writer
May 23, 2025
6 min read
Shane Rice credits Gen Ed class — and professor’s wall of declassified intelligence photos — with illuminating career path
Part of the
Commencement 2025
series
A collection of feat
A collection of features and profiles covering Harvard University’s 374th Commencement.
The professor’s office was wallpapered with declassified U.S. intelligence photos.
“I walked in and the first thing I saw were these floor-to-ceiling printouts of U2 and CORONA aerial imagery,” recalled Shane Rice ’25. “I took one look and thought — maybe there’s something here.”
Rice, 26, a U.S. Marine Corps veteran, needed a new scholarly focus. When he first arrived at Harvard from Warrenton, Virginia, he had his sights set on environmental engineering. But the field proved a poor fit for his interests and talents. “So I went on this search,” he recalled. “I got lunch with all these different department heads including integrative bio and environmental science public policy.”
The quest ended in the office of Jason Ur, Stephen Phillips Professor of Archaeology and Ethnology, with its collection of aerial landscapes. The display resonated with Rice, in part due to his military training. As a mortarman, he frequently worked with maps and satellite imagery over three deployments.
Rice was drawn to Ur’s introductory “Can We Know Our Past?” course. The Cabot House resident, who settled into College life with the help of the Warrior-Scholar Project and other veteran supports, later won a prize for his essay on the clarity he gained during the Gen Ed offering.
The curriculum, he wrote, helped him reconcile a calling to public service with interests in antiquities, procedure, organizing data, and working in places far from home. “Shane wrote very eloquently about how studying archaeology helped him figure out the transition to academia from the military,” Ur said.
“Shane wrote very eloquently about how studying archaeology helped him figure out the transition to academia from the military.”
Jason Ur
Those Cold War-era stills that captivated Rice allow Ur to survey sites in Syria, Turkey, and Iran. Since 2012, the technique has helped Ur scour the Kurdistan region of Northern Iraq for traces of ancient atrocities. Rice became the rare undergraduate to join Ur’s fieldwork in the semi-autonomous region. He even applied Ur’s methods to an investigation of scars left far more recently in the area. Rice used declassified satellite reconnaissance to uncover hundreds of lost settlements, all destroyed during Iraq’s suppression of ethnic Kurds.
“In 1987, the Iraqi Army, under the regime of Saddam Hussein, cleared the entire plain where we’re working of its rural Kurdish villages,” Ur said. “The intensive mapping Shane did offers us a great analogy for understanding the distribution and density of rural settlements in the deeper past. But it also stands as a testament to genocidal state actions.”
Visiting Ur during weekly office hours became a new habit for Rice. That’s how he learned of the professor’s fieldwork around the city of Erbil, capital of the Kurdistan Region. Ur collaborates with researchers there to sift the area for features dating to the Neo-Assyrian Empire (ca. 900-600 B.C.)
“We’re there to test the hypothesis that the Assyrian kings engaged in large-scale deportation,” explained Ur, noting that the rulers’ accounts are corroborated by their victims in the Hebrew Bible.
Also pocking the region’s landscapes is evidence of recent demographic assaults. Hussein was eventually charged with killing tens of thousands of Kurds during the 1988 Anfal campaign. U.S. news coverage has often focused on the government’s use of chemical weapons against Kurdish civilians but less so on the destruction, a year earlier, of rural farming villages.
“We don’t think of the 1980s as being terribly archaeological,” said Ur, who helped Rice settle on these villages for his thesis topic. “But this was the same tragic story told 3,000 years after the Assyrians. And it really needed some dedicated work.”
Rice was invited to join Ur on the Erbil plain just before his junior year. “I choose my team very carefully, because we’re basically as an extension of American diplomacy when we’re there,” Ur said. “Shane impressed me early on with his extraordinary responsibility and discipline, which I’m sure comes from his military background.”
The archaeology concentrator had been toying with specializing in nomad pastoralists. Rice, who also completed a language citation in Russian, arrived in Erbil after spending weeks with reindeer herders in northern Mongolia. But Ur’s work in the Kurdistan Region felt far more urgent. “They’re racing against the clock with this project,” Rice said. “They’re racing against urban development and sprawl to try to document these sites.”
Upon returning to Cambridge, Rice immediately set about structuring his own research project. Foundational to his approach was Ur’s graduate-level course on archaeological applications of Geographical Information Systems. Rice started searching government databases that semester for declassified intelligence photos that fit his needs in terms of resolution, timescale, and coverage of the 3,000-square-kilometer survey area.
That’s how he discovered a cache of high-resolution landscape images, declassified in 2013, that were collected in June 1980 by the KH-9 Hexagon U.S. photo-reconnaissance satellite. “In a perfect world, you would compare photos taken right before and right after the point of impact,” Rice said. “But 1980 was pretty close to the time we were looking at.”
Matching these satellite captures to contemporary commercial imagery enabled Rice to document hundreds of destroyed settlements. The village of Shakhulan, he found, had been plowed over, appearing in modern images as little more than cultivated fields. Standing in place of other locales were new construction or ruins.
Rice compared images from 1980 and 2013 to document destroyed settlements in the Kurdish Region of Iraq.
Images courtesy of Shane Rice
“Sometimes there is literally the footprint of the four walls that once made a building,” Rice said.
The 1980 set also revealed a tightly gridded refugee complex, or mujamma’a, that matched one described in a 1993 Human Rights Watch report. By then, the undergraduate knew the history’s rough contours from his Kurdish collaborators and friends. The Anfal campaign followed years of the Iraqi military forcibly removing Kurds to tent camps like the one he identified 25 kilometers south of Erbil.
“These sites have existed purely in oral tradition and memory,” said Rice, who will begin at Cornell Law School in the fall. “And here we have primary-source evidence of one of these sites that thousands of individuals and families were moved through. To me, that speaks to the real value of doing this project.”
Campus & Community
University sues Trump administration over move to bar international students, scholars
Harvard Yard.Photo by Grace DuVal
Alvin Powell
Harvard Staff Writer
May 23, 2025
5 min read
Judge grants University’s motion for temporary restraining order, blocking government’s action
A federal judge on Friday issued a temporary restraining order blocking the Trump administra
A federal judge on Friday issued a temporary restraining order blocking the Trump administration from revoking Harvard’s ability to enroll international students and to sponsor international scholars.
The ruling by U.S. District Judge Allison D. Burroughs prevents the government from “implementing, instituting, maintaining, or giving effect” to the revocation. In a message to the community Friday afternoon, President Alan Garber said that a hearing has been set for Thursday to determine whether the restraining order will be extended.
Harvard’s initial complaint on the matter, filed early Friday, called the Trump order “a blatant violation of the First Amendment, the Due Process Clause, and the Administrative Procedure Act.”
Harvard’s actions were prompted by the Trump administration’s latest escalation in its dispute with the University. In a letter sent Thursday, Homeland Security Secretary Kristi Noem wrote that the University’s Student and Exchange Visitor Program certification had been revoked, effective immediately, claiming the action was a result of Harvard’s failure to adequately comply with an April 16 government request seeking records related to international students. The letter and the secretary’s accompanying press release also cited grievances against the University that were unrelated to Harvard SEVP participation, applicable regulations, or Harvard international students.
The motion for a temporary restraining order, filed shortly after the main complaint, sought an immediately halt to the government’s action, arguing that the revocation would inflict irreparable harm on the University and its students. It cites the human costs of no longer being able to sponsor or host thousands of students and scholars, whose lives and work face major disruptions. The action by the Trump administration is “undisguised retaliation,” and “quintessential arbitrary, irrational, and unilateral executive action,” the motion says. “The effects on Harvard’s students — all of its students — will be devastating. Without its international students, Harvard is not Harvard.”
In a message sent to the community Friday morning, Garber said that the University has complied with the government’s records request to the extent required by law.He condemned the Noem order and vowed to fight it.
“The revocation continues a series of government actions to retaliate against Harvard for our refusal to surrender our academic independence and to submit to the federal government’s illegal assertion of control over our curriculum, our faculty, and our student body,” he said.
“We condemn this unlawful and unwarranted action. It imperils the futures of thousands of students and scholars across Harvard and serves as a warning to countless others at colleges and universities throughout the country who have come to America to pursue their education and fulfill their dreams.”
International students at Harvard hail from more than 140 countries and make up about a quarter of its student body. In her letter, Noem said the certificate revocation means Harvard cannot host nonimmigrant international students or scholars on F- or J-visas for the 2025-26 academic year. That means current students in those visa categories have to transfer to other institutions in order to maintain their visa status, she wrote.
The order left researchers, fellows, and students shaken and angry — and worried about the implications for the country and the University. Among them was Eduardo Vasconcelos, a senior from Brazil whose family arrived in Boston for Commencement week hours before the Trump administration issued its order.
“It was hard to hold back my tears” when he heard of the Noem letter, Vasconcelos said. “The order from the administration felt like a rejection of the four years that I have spent at Harvard and an attack on the immense work that international students and scholars dedicate to the production of knowledge relevant to the United States and to the world.”
If the action were to take effect, said Vasconcelos, an honors concentrator in government and economics, the country would suffer an “immeasurable” loss of “vitality, of intellectual diversity, and of an opportunity to do good for the world.”
He added: “The federal administration is harming the capacity of America’s oldest educational institution to serve as a staircase open to all. This horrific decision limits the ability of our institution to help address the world’s most pressing challenges, which invariably requires identifying talents and voices from all over the world and bringing them to Harvard.”
Scott Delaney, an epidemiologist at the Harvard Chan School whose research has yielded insights on the health effects of air pollution and other environmental hazards, said that the action by the Trump administration threatens what should be a source of pride for the nation.
“The United States is the global leader in health science research because the best researchers from all over the world come here as students, and then they stay and build their careers,” he said.
“I personally work with students and postdocs from at least five different countries on research to improve the lives of Americans living with Alzheimer’s disease. If we kick them out just because they were born somewhere else — as the Trump administration is trying to do — then my team simply won’t produce as much high-impact research, and the United States will lose out on their insights and contributions. All of these world-class researchers will just take their talents elsewhere.”
Garber closed his message to the community by directly addressing international students and scholars: “You are our classmates and friends, our colleagues and mentors, our partners in the work of this great institution. Thanks to you, we know more and understand more, and our country and our world are more enlightened and more resilient. We will support you as we do our utmost to ensure that Harvard remains open to the world.”
Robert Huckman and Isaac Kohlberg.Harvard file photos
Health
Miracle drugs don’t come out of nowhere
Healthcare, innovation experts say funding cuts to university labs will slow or stop the basic research on which breakthroughs are built
Jacob Sweet
Harvard Staff Writer
May 22, 2025
5 min read
The world’s most significant medical therapies often spring from surprising sources.
It would
“If one thinks pharmaceutical prices are high today, it is safe to assume they will become even more so in the face of these funding reductions.”
Robert Huckman
But while the story of any individual breakthrough might seem improbable, the pattern repeats. Basic, fundamental research — often paid for by the government and conducted by university faculty and students — leads to transformative drugs and technology.
With recent cancellations of research grants, experts in medical science worry that the U.S. may lose its long-held advantages in research and development for decades to come.
“If these grants are not restored, it would not be surprising to me if 10 years from now, we see a markedly lower number of therapies coming to market,” said Robert Huckman, the Albert J. Weatherhead III Professor of Business Administration at Harvard Business School and the Howard Cox Faculty Chair of the HBS Healthcare Initiative. “That’s a real risk.”
Isaac Kohlberg, senior associate provost and the University’s chief technology development officer, agreed.
“If you attack the foundation of the building, the building will collapse,” he said. “Academic innovations are the foundation of many products and services that reach consumers. If we fail to invest in the necessary resources to advance fundamental discoveries, universities’ labs may shrink, and the U.S. innovation ecosystem will decline.”
These problems start from the outset of the innovation pipeline.
“To treat disease, we need to understand how it works,” Huckman said. “And understanding how disease works is a complicated problem.”
By the time a company decides to invest in a clinical trial for a new treatment or intervention, years — or decades — of government-funded research have generally taken place.
“You have to think about it as a building block,” said Kohlberg. “Without basic research, there is no translational research.”
“It’s not the role of companies to invest in basic research,” Kohlberg pointed out. “Companies are set up to make money, to develop products. It’s more immediate outcomes.”
They do, however, closely monitor government-funded research, the results of which must be released to the public.
A multitude of companies, for example, build off the revolutionary gene-editing technology CRISPR or develop GLP-1 drugs — even though portions of early research behind the technologies took place at Harvard.
“You have to have a model there to take big swings at problems,” Huckman said. “And I think that the relationship between government and academic institutions has historically been one that has allowed those big swings to be taken.”
When money going to early research dries up, so does the opportunity to commercialize promising developments.
“You could begin to see a narrowing of research portfolios that could apply both to the research labs themselves as well as those organizations that hope to commercialize the technologies those labs would have discovered,” said Huckman.
Biotech companies hoping to pursue technologies that could help treat many different diseases might see cuts to basic research and decide to pursue less ambitious goals.
“There’s a chain of activities to get from an understanding of basic science to an approved treatment,” explained Huckman. “If we break or weaken one link in that chain, we compromise the whole process.”
Kohlberg sees a similar potential spiral: With less research funding, fewer ideas will come out of universities; startups won’t be able to develop those ideas; and larger companies that have traditionally identified, acquired, and funded promising startups will see fewer opportunities to do so.
“It’s like a funnel,” he said. “Eventually the patient’s going to have fewer options.”
And more expensive ones.
Huckman pointed out that if pharmaceutical companies need to take on riskier, early stage research, they’ll have to recoup it when pricing whatever drugs they are able to bring to market.
“If one thinks pharmaceutical prices are high today, it is safe to assume they will become even more so in the face of these funding reductions,” he said.
For both Kohlberg and Huckman, cutting off the university-government partnerships puts the entire system of American innovation into disarray.
“These cuts mean there is no oxygen going to the research enterprise,” Kohlberg said. “This will completely undercut the future of innovation.”
Health
Vitamin D supplements may slow biological aging
Telomeres are the protective caps found at the ends of chromosomes.Illustration/Getty Images
Mass General Brigham Communications
May 22, 2025
3 min read
Trial shows protection against telomere shortening, which heightens disease risk
Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, pro
Telomeres are the protective caps found at the ends of chromosomes.
Illustration/Getty Images
Mass General Brigham Communications
3 min read
Trial shows protection against telomere shortening, which heightens disease risk
Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.
The new report, which is published in The American Journal of Clinical Nutrition, is based on data from a VITAL (VITamin D and OmegA-3 TriaL) sub-study co-led by researchers at the Harvard-affiliated Mass General Brigham and the Medical College of Georgia, and supports a promising role in slowing a pathway for biological aging.
“VITAL is the first large-scale and long-term randomized trial to show that vitamin D supplements protect telomeres and preserve telomere length,” said co-author JoAnn Manson, the principal investigator of VITAL and chief of the Division of Preventive Medicine at Harvard-affiliated Brigham and Women’s Hospital and the Michael and Lee Bell Professor of Women’s Health at Harvard Medical School.
“This is of particular interest because VITAL had also shown benefits of vitamin D in reducing inflammation and lowering risks of selected chronic diseases of aging, such as advanced cancer and autoimmune disease,” said Manson.
JoAnn Manson (center) meeting with members of the VITAL research team.
Credit: BWH
Telomeres are made of repeating sequences of DNA, or base pairs, that prevent chromosome ends from degrading or fusing with other chromosomes. Telomere shortening is a natural part of aging and is associated with an increased risk of various age-related diseases.
A few short-term, small-scale studies have suggested that vitamin D or omega-3 fatty acid supplementation may help support telomeres, but results have been inconsistent. VITAL is a randomized, double-blind, placebo-controlled trial of vitamin D3 (2,000 IU/day) and omega-3 fatty acid (1 g/day) supplementation that tracked U.S. females aged 55 years and older and males aged 50 years and older for five years. The VITAL Telomere sub-study included 1,054 of these participants, whose telomere length in white blood cells was assessed at baseline and at Year 2 and Year 4.
Compared with taking placebo, taking vitamin D3 supplements significantly reduced telomere shortening over four years, preventing the equivalent of nearly three years of aging. Omega-3 fatty acid supplementation had no significant effect on telomere length throughout follow-up.
“Our findings suggest that targeted vitamin D supplementation may be a promising strategy to counter a biological aging process, although further research is warranted,” said Haidong Zhu, first author of the report and a molecular geneticist at the Medical College of Georgia, Augusta University.
Mass General Brigham-affiliated authors include Nancy R. Cook, William Christen, and I-Min Lee. Additional authors include Haidong Zhu, Bayu B. Bekele, Li Chen, Kevin J. Kane, Ying Huang, Wenju Li, and Yanbin Dong.
This work was supported by the National Heart, Lung and Blood Institute.
Campus & Community
Less a problem than an adventure
Jacob Sweet
Harvard Staff Writer
May 22, 2025
5 min read
For Eliot Hodges, math is a creative process
Part of the
Commencement 2025
series
A collection of features and profiles covering Harvard University’s 374th Commencement.
For the typical high-schooler, math is a plug
A collection of features and profiles covering Harvard University’s 374th Commencement.
For the typical high-schooler, math is a plug-and-play activity. You study a problem, figure out how to find the answer, and then apply what you’ve learned to a test. Creativity isn’t part of the process.
That was how Eliot Hodges, a graduating mathematics concentrator in Dunster House, experienced the subject before College. He enjoyed math — and did well on exams — but unlike some of his future classmates, left it behind when he left the classroom.
It was music that held his attention.
The third of four musically inclined siblings, Hodges studied cello — taking lessons, attending summer music programs, participating in youth orchestras, and competing in solo competitions. With his siblings, he founded InTune String Ensemble, a nonprofit that raises funds for different children’s organizations. After collecting door-to-door donations, the group realized they could raise more money playing gigs and busking around Denver. “When we started we were quite young,” Hodges said. “I think that factor helped a lot.”
During his senior year, just as he was deciding that he didn’t want to pursue music professionally, Hodges enrolled in a remote linear algebra class. He didn’t realize it at first, but the course was proof-based — focusing less on pure application and more on theorems and other mathematical statements. “I remember pulling up some practice exercises for the midterm and not knowing how to do a single one,” he said. To study, he ended up copying down the solutions to try to teach himself to write proofs. He liked that sense of exploration.
“You’re not really being taught how to do the problems,” Hodges said. “You really have the opportunity to be creative in how you think about problems, and I really fell in love with that approach.”
During a gap year, he studied as much math as he could and took a few classes through the University of Colorado at Boulder, becoming especially interested in number theory, which is a branch of pure mathematics devoted to the study of whole numbers — and especially prime numbers — and how other numbers can be built by multiplying primes, along with the patterns that emerge from that process.
“In a way, prime numbers are the mathematical atom, which is why they are so ubiquitous,” he explained, “and despite being so fundamental to math, some aspects of the primes are still very mysterious.” He liked how simple questions about the primes opened into complex problems.
“Sometimes you are banging your head against the wall, and then you realize that if you step back and move two feet over you can find an open door.”
Hodges didn’t sleep much during his first year at Harvard, but he did learn a lot of math — including through a number theory class with Gerhard Gade University Professor Barry Mazur. He was struck by the elegance of concepts like Fermat’s last theorem, which an elementary school student could comprehend but required 300 years of mathematical development to prove. “Often, solving problems in number theory requires applying ideas from different mathematical fields,” he said, “And you have to be very creative with how you bring everything together.”
After a grueling first year, he vowed to tone down his quantitative courseload to two math classes, plus research. One of the math classes had to be what Hodges called a “vegetable.”
“A vegetable class is one that is good for me,” he explained. “It would expand my horizons and be very useful later on.” The other kind of class was a “chicken nugget,” where he came in liking the material.
The combination of depth and breadth helped his research. Often, he explained, it’s harder to identify a novel problem than it is to actually solve it. “Once you have a greater understanding of what you want to say about the mathematical objects you’re studying, the work is, one hopes, more straightforward,” he said. “A lot of the hard work is in conceiving your ‘mathematical thesis statement.’”
For one project, his goal was to calculate the distribution of a certain kind of random group with an additional piece of algebraic data called a pairing. “The naïve generalization of known methods for approaching the problem didn’t work,” he said, but once he stopped thinking about the pairing as a function and thought about it as an identification of the group with its dual — a mirror image of the group — he was able to apply known techniques to solve the problem. “Sometimes you are banging your head against the wall, and then you realize that if you step back and move two feet over you can find an open door.”
It helped to have support and guidance from William Caspar Graustein Professor of Mathematics Melanie Matchett Wood, who mentored Hodges for three years and advised his thesis along with Benjamin Peirce Fellow and NSF Postdoctoral Fellow Ashvin Swaminathan.
Hodges also kept the door open to cello, taking lessons with Professor Kee-Hyun Kim of the Parker Quartet and enrolling in “MUS189R: Chamber Music Performance” each semester. Some of his favorite campus memories include playing with his sister Eloise Hodges ’22 and performing end-of-semester recitals with Christian Chiu ’25, his roommate and an accomplished pianist. The two share a background in intense musical study and a desire to focus on having fun playing together. “The recitals feel very triumphant,” he said, smiling, “even if they go badly.”
After graduating, Hodges will pursue a one-year M.A.St. in pure mathematics at the University of Cambridge as a Churchill Scholar before enrolling in a mathematics Ph.D. at Princeton.
He hopes that his time at Cambridge will help him master techniques from other mathematical fields that he can apply to number theory. The more math he can learn, the more creative he can be. “The most exciting part,” he said, “is that you might discover a connection that other people haven’t thought about before and contribute something meaningful to the field.”
Science & Tech
Chance to branch off in new directions
Kermit Pattison
Harvard Staff Writer
May 21, 2025
8 min read
Seven novel research projects awarded grants by Star-Friedman Challenge
The quest for scientific truth leads Harvard researchers to a wide array of pursuits: sea slugs that steal body parts from other animals, microwave resonator telescopes powerful enough to detect tra
Seven novel research projects awarded grants by Star-Friedman Challenge
The quest for scientific truth leads Harvard researchers to a wide array of pursuits: sea slugs that steal body parts from other animals, microwave resonator telescopes powerful enough to detect traces of the Big Bang, and lab-grown human kidneys.
The program provides seed funding for Harvard faculty to conduct research in the life, physical, and social sciences. Star-Friedman supports promising research that might not be funded by traditional sources and encourages investigators to explore new directions branching off their previous work.
The program was established in 2013 by a gift from James A. Star ’83 and expanded five years later by support from Josh Friedman ’76, M.B.A. ’80, J.D. ’82, and Beth Friedman. The 2025 winners were recognized in a ceremony at University Hall on Wednesday.
Cellular basis of organelle theft
Photo by Dylan Goodman
Corey Allard, Assistant Professor of Cell Biology, Harvard Medical School
Project: How do some species make use of body parts purloined from other animals? New insights may come from sea slugs that have evolved the ability to steal organelles (specialized structures within cells) from other species.
For example, so-called “solar powered” sea slugs from the genus Elysia pilfer the chloroplasts of algae cells and then use them for photosynthesis for up to one year. Other sea slugs from the genus Berghia pilfer the stinging organelles of sea anemones and place them on their own backs to deter predators.
Allard and colleagues will investigate the biological mechanisms that allow these slugs to maintain the stolen organelles.
Goal: The long-term aim of this “slug-inspired” research is to engineer cells capable of maintaining foreign organelles. The work also may offer insights into preventing diseases caused by intracellular parasites such as tuberculosis and malaria.
Sensing water and the evolution of terrestrialisation in invertebrates
Josefina del Mármol, Assistant Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Project: One of the great events in the history of life occurred when aquatic animals colonized land. The del Mármol team will investigate one facet of this mystery: How did ancient invertebrates adapt the sensory organs required for living on terrestrial environments?
Insects — the largest group of species on Earth — are believed to have evolved humidity receptors from organs called ionotropic variant receptors. These organs still exist in aquatic arthropods that have no history of living on land and thus never had the need to monitor air humidity.
This study will examine how these organs function in species still living in water, specifically American lobsters.
Goal: The team seeks to reveal how invertebrates evolved the ability to monitor the humidity of air. The del Mármol lab specializes in studying olfaction in invertebrates, and this new area of research — the neurobiology and evolution of sensory organs in early terrestrial animals — represents a new direction.
Shedding light on the Big Bang with a novel microwave resonator
John M. Kovac, Professor of Astronomy and Physics
Project: The Big Bang is still making waves — and a Harvard research team hopes to detect more of them.
The Kovac group has built telescopes at Amundsen-Scott South Pole Station that are capable detecting faint radiation from the Big Bang 14 billion years ago.
Cosmic Microwave Background (CMB) is the oldest light in the universe and contains clues about its history. One theory predicts that primordial gravitational waves have left faint patterns of polarization.
The development of telescopes capable of observing these patterns is a top priority for the scientific fields of high-energy physics and cosmology.
To map the microwave sky, these telescopes must detect slight variations in thermal brightness in an environment billions of times brighter. This requires precise microwave optics cooled to cryogenic temperatures — a steep technical challenge.
Goal: The team proposes a novel use of optical resonant cavities (an arrangement of componentsthat repeatedly reflects the targeted spectrum) to study microwave photons.
Similar technologies already have been used in other fields: Laser cavities have helped detect gravitational waves and microwave cavities have helped search for dark matter particles.
The group already has built a promising prototype and hopes to extend this work to a broader range of frequencies and temperatures and to identify the most promising materials.
Validating child-friendly measures of global brain energetics to address new questions in the study of obesity, diabetes, and the role of nutrition in healthy brain/cognitive development
Christopher Kuzawa, Professor of Human Evolutionary Biology
Project: The human brain is a greedy organ. In adults, it accounts for only 2 percent of our bodyweight but consumes about one-fifth of our energy. In children, the brain is even more demanding: It consumes about two-thirds of resting energy around age 5.
After the brain has nearly reached full size, the peak energy demand occurs during an intensive phase of creating new synapses and pruning them between ages 4 and 6. During this time, body growth slows and body fat drops to its lowest stage in the human lifespan.
When brain energy demand subsides, children start to regain body fat — a phenomenon known as the “adiposity rebound.” These processes have implications for public health: Kids who experience the rebound earlier tend to become heavier adults.
Better understanding of these dynamics also may shed light on chronic disease such as adult diabetes and long-term outcomes such as schooling and income.
Goal: Investigating these questions requires more “kid-friendly” techniques for measuring brain energy consumption. The preferred technique — PET scans with radioactive tracer dyes — is not practical for children.
Instead, Kuzawa and colleagues propose using Magnetic Resonance Imaging (MRI) to measure cerebral blood flow as a proxy for brain energy consumption.
But the accuracy of this technique must be validated by comparison to other methods and the investigators propose to do so in a study with 25 adults. If successful, these kid-friendly MRI methods could be used to investigate childhood brain energetics and the implications for public health.
Biofabrication of human kidney tissues for therapeutic use
Photo by Rick Groleau
Courtesy photo
Jennifer A. Lewis, Hansjorg Wyss Professor of Biologically Inspired Engineering, and Jianming Yu Professor of Arts and Sciences, Harvard John A. Paulson School of Engineering and Applied Science
Leonardo Riella, Harold and Ellen Danser Associate Professor of Surgery, Harvard Medical School, Medical Director of Kidney Transplantation, Massachusetts General Hospital
Project: Chronic kidney disease affects more than one in seven U.S. adults, or more than 35 million people. More than 800,000 Americans suffer from end-stage renal disease and require dialysis or kidney transplant. But demand for transplants is about four times higher than the number of kidneys donated per year.
Goal: Lewis and Riella hope to develop a revolutionary new treatment for patients with end-stage renal disease, seeking to engineer lab-grown kidneys from human stem cells.
They will employ induced pluripotent stem cells to fabricate human kidney organoids in the lab then transplant small versions of these human kidneys into mice to study their function.
If successful, these techniques would represent a step towards fabricating kidneys for human patients.
How to regenerate a limb? Integrating analyses of metabolism and developmental biology
Harvard file photo
Photo by Tony Rinaldo
Jessica Whited, Assistant Professor of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute
George V. Lauder, Professor of Organismic and Evolutionary Biology, Henry Bryant Bigelow Professor, Museum of Comparative Zoology
Project: Salamanders have an enviable ability: They can regrow severed limbs. This remarkable trait is a classic example of regeneration often described in biology textbooks, yet little is known about the energetic costs.
Whited and Lauder seek to understand the molecular and metabolic changes that occur during limb regeneration. Focusing on a species of salamander called axolotls, they aim to answer a fundamental question: How much does it cost to regrow a limb?
The investigators posit that salamanders fuel the generation process by boosting their metabolic rate by autophagy, a process in which cells break down their own components and use the molecules as fuel.
Goal: The work will illuminate the biological regulators of limb regeneration and why they work in some species but not others. The researchers hope the work will generate insights that might be applied to human patients who have lost limbs.
Turn the best photovoltaics into new high Tc superconductors; realize unconventional superconductivity in twisted perovskites
Niles Singer/Harvard Staff Photographer
Harvard file photo
Suyang Xu, Assistant Professor of Chemistry
Ashvin Vishwanath, George Vasmer Leverett Professor of Physics
Project: Can the most promising photovoltaic materials be turned into high-temperature superconductors? This question drives a new collaboration between a theorist and experimentalist of quantum materials.
Goal: Metal halide perovskites have been demonstrated to be an extremely efficient material for solar cells. Now the two investigators propose using these materials for high-temperature superconductors.
They propose that the twisted bilayer of metal halide perovskite may serve as a platform for high-temperature superconductivity. In their proposal they assert, “This seemingly crazy idea is not only possible … but promising.”
In the partnership, Vishwanath will perform theoretical calculations while Xu will lead the experiments. If successful, this application would be a groundbreaking discovery. The researchers also will test theoretical questions and potentially bridge two emerging fields.
Kelsey Hanson Woodruff.Photo by Grace DuVal
Campus & Community
Searching for answers to life’s big questions
Kelsey Hanson Woodruff served as a Presbyterian minister before love of religious studies led her to Harvard
Liz Mineo
Harvard Staff Writer
May 21, 2025
5 min read
Part of the
Commencement 2025
series
A collection of features and pr
A collection of features and profiles covering Harvard University’s 374th Commencement.
Growing up in a Catholic family in California’s Bay Area, Kelsey Hanson Woodruff’s path from altar girl to Presbyterian minister to scholar of American religion seemed somehow preordained.
“I have always been interested in religion, because to me, the question of why humans are here and how they make meaning is important,” said Hanson Woodruff. “I have always been interested in how religion affects society, and how people’s religious faiths inform how they want society to run, and what kind of a community they imagine.”
“They set an example for me, that your ministry can be lived out in your personal life as well as in the classroom.”
Kelsey Hanson Woodruff
Hanson Woodruff’s Catholic upbringing, and the presence of many educators in her tight-knit family helped her foresee a path in which education and religion could be intertwined. The example of her godparents, who are also her uncle and aunt, Eric Hanson, a former Jesuit priest, and Kathleen Hanson, a former Maryknoll nun, looms large in her life, she said. They met after both had left the church and become college professors. “They set an example for me, that your ministry can be lived out in your personal life as well as in the classroom,” she said.
Still, it was only after taking a class in Buddhism at Stanford that Hanson Woodruff fell in love with religious studies. Drawn by Protestant churches’ policy of ordaining women, she became a Presbyterian minister and served congregations in California, Arizona, and Massachusetts in the years before she came to Harvard.
A Ph.D. candidate in religion with a secondary in anthropology in the Kenneth C. Griffin Graduate School of Arts and Sciences, Hanson Woodruff studies transformations in American Christianity. Her dissertation, a historical and ethnographic study of post-evangelical feminists, explores the impact of digital technologies and societal changes on faith, and underlines her interest in studying progressive religious people.
“In the United States, we often hear only about conservative Catholics, conservative evangelicals, and conservative Christians,” Hanson Woodruff said. “But there are religious people on the left, and there are progressive people within all religious communities. There’s certainly some scholarship on it, but there should be more; there needs to be more public knowledge about that.”
In her fieldwork, much of which took place during the pandemic, Hanson Woodruff researched a number of digital religious communities led by women who were pushing back against conservative streams within evangelical Protestantism. As a millennial, she was interested in how these women leaders were using digital media, including blogs, social media, and digital forums, to explore their Christian faith.
Among the figures Hanson Woodruff studied were Rachel Held Evans, author of the New York Times best-seller “A Year of Biblical Womanhood” (2012); Sarah Bessey, who published “Jesus Feminist” (2013); and Austin Channing Brown, who wrote the best-selling “I’m Still Here: Black Dignity in a World Made for Whiteness” (2018).
As progressive Christian authors, Evans, Bessey, and Channing Brown challenged traditional views within the evangelical church on politics, feminism, anti-racism, and LGBTQ issues, said Hanson Woodruff. Held Evans, who died at 37 in 2019, wrote about how she grappled with her conservative upbringing while questioning long-established evangelical views on the role of women. Bessey asked readers to reconsider whether feminism was antithetical to Christianity. Channing Brown wrote about her experience as a Black Christian woman in white conservative evangelical spaces.
“Many of these women authors are advocating for alternative theologies within conservative evangelicalism.”
Kelsey Hanson Woodruff
“Many of these women authors are advocating for alternative theologies within conservative evangelicalism,” said Hanson Woodruff. “Many of them were raised in churches where women would not be allowed to be pastors or elders or other kinds of leaders. And they’re talking to each other, and saying that that’s not in the Bible, and that’s not what it says. And their readers are reconsidering these things as well.”
Hanson Woodruff’s work will have a significant academic impact, said David Holland, Bartlett Professor of New England Church History at Harvard Divinity School.
“Kelsey’s ability to identify the way technology and culture have converged to create these spaces and opportunities for women’s religious leadership in spaces that have traditionally been reserved for male leadership has been a really important breakthrough in our understanding of the religious landscape of our present moment,” said Holland.
After graduation, Hanson Woodruff plans to pursue postdoctoral studies and publish a biography of Held Evans, which she has been working on for the past few years. In the meantime, she has a few words of advice for those students interested in religious studies. “Young adulthood is a wonderful time to consider the most significant questions of meaning: What makes us human? What is our purpose? And how have other people, in other times and other places, understood the answers to these questions?” said Hanson Woodruff. “Religious studies, and indeed all the humanities, can lead us to consider these things.”
Science & Tech
‘We have a way of steering a fly like you would a car’
Kenichi Iwasaki working with fruit flies.Photos by Niles Singer/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
May 21, 2025
4 min read
Geneticists find method to turn tiny bugs into living robots
Fruit flies, one of the most studied organisms in science, are efficient little creatures, able to navigate
‘We have a way of steering a fly like you would a car’
Kenichi Iwasaki working with fruit flies.
Photos by Niles Singer/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
4 min read
Geneticists find method to turn tiny bugs into living robots
Fruit flies, one of the most studied organisms in science, are efficient little creatures, able to navigate their environment with agility. They were also one of the first animals to be manipulated by geneticists.
A new study, published last month by PNAS, exploited these qualities by turning fruit flies into what the co-authors call “living micro-robots,” whose movements can be controlled by sensory clues. The paper was completed at Harvard’s Rowland Institute, dedicated to experimental research across engineering and science disciplines.
“Typically, people think about robots as devices that you build with plastic and metal and the wires and software,” said co-author Aleksandr “Sasha” Rayshubskiy, a fellow at the Rowland Institute. But because fruit flies — aka Drosophilae melanogaster — are so well understood, they can be treated as living robots.
“You can get them to do things that you want them to do,” Rayshubskiy said.
The research team includes: Kenichi Iwasaki (from left), Sasha Rayshubskiy, Chris Stokes, and Charles Neuhauser (not pictured).
The research team used two methods to manipulate the flies’ movements, the first involving light and a wheel. “We can rotate the light and wheel either clockwise or counterclockwise, and that makes the flies turn,” explained Charles Neuhauser, a postbaccalaureate fellow on the study.
The second method involved scent, again used to get the flies to one side. “We get them to think that they are smelling something either to the left of their body or to the right of their body,” Neuhauser said.
The paper describes how these controls were used to lead flies through a maze and block out phrases like “Hello, world,” a familiar greeting to computer programmers. “We can hack their genes to turn on actions,” said co-author Kenichi Iwasaki, a research associate at the Rowland Institute. “We can hack them the same way that you would hack a conventional robotic system. We have a way of steering a fly like you would a car.”
But do these flies really constitute robots? “Our work pushes that conceptual boundary,” Rayshubskiy said. “I think a robot is a machine that you can get to do useful work for you.”
The project is the result of “two fields that normally don’t interact,” he added. “You have the field of engineering where people build robots. They don’t really see the fly as a player yet in that world. And then you have a field of people who care deeply, very deeply about fruit flies, but they don’t really venture into the robotic field.
“I’ve engineered myself into this bridge between these two fields,” Rayshubskiy said.
Although the fruit fly’s 1 mg, 2.5 mm body is tiny, Rayshubskiy sees multiple possibilities for future applications. “They can carry about their own weight,” he pointed out. “We could not only guide them places, but we can also activate behaviors inside of them where they could do something else.”
He gave a practical example. “It’s actually really hard to clean buildings,” Rayshubskiy said. “They’re covered in junk constantly and it builds up over time. Imagine having a swarm of fruit flies, thousands and thousands of flies, that you could direct onto the face of a building, and they would clean all the dirt that builds up. You could use swarms of flies as cleaning devices.”
A second paper, currently being finalized by the same set of researchers, addresses how fruit flies can be made to interact with foreign objects, essentially exploring their potential as tiny beasts of burden.
“Our work provides a foundation for deploying swarms of natural ‘robots’ that, with further innovations, could transform applications like environmental monitoring and disaster response,” said Rosy Hosking, director of research affairs at the Rowland Institute.
The forthcoming research also gives insight into the workings of the fruit fly brain. “There’s tension between our guidance, which doesn’t know or care about how the fruit fly feels, and the fly’s own feelings about what feels safe to do,” Rayshubskiy said. By studying that tension, and the fruit fly’s responses, he said, “We could tease out the hidden variables about what the fly cares about by forcing it to do certain things.”
Health
We know exercise is good for you. Why? He‘s working on it.
Building on decades of research, Robert Gerszten seeks to pinpoint movement’s molecular benefits
Anna Lamb
Harvard Staff Writer
May 21, 2025
4 min read
Robert Gerszten in his lab.Veasey Conway/Harvard Staff Photographer
Part of the
Profiles of Progress
series
We know exercise is
We know exercise is good for us — but not exactly why. At Harvard, researchers are trying to pinpoint how exercise impacts our bodies down to the cellular level.
“It’s been known since Hippocrates that exercise is associated with health,” said Robert Gerszten, a professor at Harvard Medical School and chief of cardiovascular medicine at Beth Israel Deaconess Medical Center. “But how exercise is beneficial at a molecular level is not well described.”
For decades, Gerszten’s lab has been tackling this question. Notably, he’s been involved in a landmark National Institutes of Health project launched in 1992 known as the HERITAGE Family Study. Drawing on data from more than 650 men and women of varying fitness levels undertaking a 20-week exercise program, the study continues to publish findings.
In 2021, Gerszten helped author a paper using HERITAGE data in which researchers were able to predict with reasonable accuracy whether individuals could improve their cardiovascular fitness, and by how much. The team used pioneering molecular tools to identify blood-based biomarkers linked to fitness and training response. Out of the more than 5,000 proteins his lab studied, Gerszten and his team were able to identify 147 that had strong predictive relationships.
“We began to identify some new biochemicals that hadn’t been described previously in the context of exercise physiology,” Gerszten said.
Building on that work, Gerszten is a part of another NIH-funded project — the Molecular Transducers of Physical Activity Consortium. His lab is one of the core chemical analysis sites analyzing clinical metrics like blood pressure, VO₂ max (a measure of cardiorespiratory fitness), and muscle strength in more than 2,000 participants. Additionally, the team is taking blood samples and tissue biopsies before and after 12 weeks of exercise to analyze molecular changes compared to baseline samples.
“The HERITAGE study was a prelude for this study,” Gerszten said. “It was the largest exercise study ever done, and it was about 650 people, so about a third of the size of this.”
“The notion is, if you identify some pathway that’s conferring a lot of the benefit of exercise, do you really need the exercise?”
Gerszten noted that this study isn’t comprehensive just because of its size, but also its breadth of patients. There are participants under 18 and over 60. And from each person, about seven blood samples are taken, along with tissue samples, during acute exercise. “Each time,” he said, “before and after training, you get muscle and fat biopsies.”
The researchers are seeking to better understand why some people respond better to different types of workouts, such as running versus weightlifting. They also hope their findings will lead to clinical applications.
“The notion is, if you identify some pathway that’s conferring a lot of the benefit of exercise, do you really need the exercise?” Gerszten said. “You can imagine that for certain individuals, wheelchair-bound, super frail, etc., these types of putative interventions might be particularly helpful.”
Early findings from pre-COVID trials of patients are starting to be released. Though Gerszten said it may be years before all the data is collected and analyzed, an unusual feature of the study is that data is being released publicly on a rolling basis to allow doctors and scientists to use it for their own research.
“This is one of the largest genomic databases,” Gerszten said. “So there’s going to be so many eyes on the data. I would underscore that the real goal is to get this out ASAP for everybody to look at.”
This research is supported by the NIH Common Fund and is managed by a program team led by the NIH Office of Strategic Coordination, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, and the National Institute on Aging, and by a trans-agency working group representing multiple NIH institutes and centers.
Robert Waldinger.Harvard file photo
Nation & World
Things money can’t buy — like happiness and better health
That’s according to the Harvard Study of Adult Development, which over its 87-year run has generated data that benefits work on other issues
Liz Mineo
Harvard Staff Writer
May 20, 2025
4 min read
Part of the
Profiles of Progress
series
In its 87th year, the longitudinal study represents the world’s longest-running scientific examination of human health and happiness. It began in 1938 with 724 participants and has grown to 2,500, including the wives and descendants of the original participants.
“The lessons aren’t about wealth, or fame, or working harder and harder,” said Waldinger in a 2015 TED Talk that has been viewed nearly 50 million times.
”The clearest message is this: Good relationships keep us happier and healthier.”
“The clearest message is this: Good relationships keep us happier and healthier. Period … It turns out that people who are more socially connected to family, to friends, to community, are happier; they are physically healthier and live longer than people who are less well connected.”
The data collected by the study over decades, consisting of medical records, brain scans, in-person interviews and questionnaires, is a treasure trove of information that can be used for research beyond that of Waldinger’s group.
As of now, the Harvard Study is collaborating with researchers from the Boston Veterans Administration, Northwestern University, University of Malmo in Sweden, and Bryn Mawr College.
One of those collaborations looks at lead exposure in childhood, through air and water, and its potential impact on physical and mental health by using the study’s data on participants and the neighborhoods where they grew up, including lead exposure, and their physical and mental well-being throughout their lives.
This collaborative study also aims to examine whether long-term effects of exposure to lead affect levels of juvenile delinquency, dropping out of school, or developing dementia later in life.
Over the years, the study has been funded primarily by grants from the National Institutes of Health, and since 2003 by grants from the National Institute on Aging.
The Harvard Study has not been affected by the Trump administration’s recent funding cuts, but the cuts pose a threat to long-term research, which can only be supported by government funding, said Waldinger.
“So many foundations will do a pilot grant,” said Waldinger. “But then they don’t want to keep funding something for eight decades, understandably, but the government can take on these longer, big projects. The government is the only funding source likely to do that.”
In the Harvard Study’s case, federal funding has covered participant testing and compensation and salaries of research assistants, who do in-person visits or phone calls, and collect and store data.
But another key benefit of federal-funding projects is that they help train young scientists who will go on to lead research discoveries, said Waldinger.
“Many of our most important discoveries are discoveries that happen because people were investigating an area that didn’t necessarily have a direct practical application when they started studying it, and then they discovered things that turn out to be hugely important things.”
Longitudinal research, or studying people over time, is a specialized kind of study that requires special statistical techniques. Over the years, dozens of undergraduate students, Ph.D. candidates, postdoctoral fellows, and junior faculty have been trained by the Harvard Study, he said.
Critics are concerned the recent funding cuts might discourage young scientists from going into research. Even if the funds are restored in the next administration, the pipeline of researchers will have been disrupted, said Waldinger. Some of his students no longer see research as a reliable career, and many are going into clinical work or business, he added, but the effects on the country’s position as a global leader in scientific research and discoveries are worrisome as well.
“My biggest worry is that we will stop being the premier place for research,” said Waldinger.
“Many of our most important discoveries are discoveries that happen because people were investigating an area that didn’t necessarily have a direct practical application when they started studying it, and then they discovered things that turn out to be hugely important things.”
In addition, much of the research has fueled economic innovation over the decades, and funding cuts also put those advances in jeopardy. “So even if you were just interested in money and not in knowledge and science, you would say, this is a really important thing to continue, and we should never lose this, or we will lose our advantage economically,” he said.
Cristina Morilla, associate paintings conservator, working in 2020 on a portrait of King Philip of Spain at Harvard Art Museums. In some cases, conservators are practitioners themselves, explains Brenda Bernier, the director of Preservation Services for Harvard Library. To understand how and why an object is falling apart, one has to know how it’s put together. “Each one is like a little puzzle.”Harvard file photo
Campus & Community
‘There are secrets to unlock’
Cristina Morilla, associate paintings conservator, working in 2020 on a portrait of King Philip of Spain at Harvard Art Museums. In some cases, conservators are practitioners themselves, explains Brenda Bernier, the director of Preservation Services for Harvard Library. To understand how and why an object is falling apart, one has to know how it’s put together. “Each one is like a little puzzle.”
Harvard’s practice of preservation plays key role in future research
Across the University and the world, Harvard students, staff, and researchers dedicate themselves to documenting, organizing, and restoring items big and small. The tools of the trade could be trowels, tweezers, erasers, microscopes, or 3D scanners, but their goal is the same: to preserve works of literature, art, science, and civilization, and keep them accessible for future generations of researchers, students, and the wider public.
“There are secrets to unlock,” says Brenda Bernier, the Malloy-Rabinowitz Preservation Librarian and director of Preservation Services for Harvard Library. “I find that the most exciting and exhilarating part of it, and also the most daunting.”
Bernier’s office is near the Weissman Preservation Center on Mount Auburn Street in Harvard Square. “Anytime you walk through that lab, there’s something that’s gonna knock your socks off,” Bernier said.
The Weissman specializes in handling and treating rare book, paper, and photographic collections. Other departments and museums around campus have their own conservation and archival specialties.
Harvard’s history in preservation and conservation runs deep. In 1928, it established the first art conservation laboratory in the U.S., called the Department of Technical Research, in the Fogg Museum. It’s now called the Straus Center for Conservation and Technical Studies.
Bernier compares the scale of Harvard’s preservation efforts to the Library of Congress. “Harvard has been collecting library materials since the 1600s,” she said. “It’s our responsibility to maintain it into the future.”
What makes Harvard’s collections of books, photographs, recordings, digital media, and ephemera so important? These original items are primary resources, and they can jumpstart new research inquiries. “They hold the witness of the time,” Bernier said. “It could be scientific data. It could be cultural and historical events. Preserving that, that powers research right there. Because it is close to the truth; it’s what actually happened.”
Scott Edwards, Alexander Agassiz Professor of Zoology in the Museum of Comparative Zoology and curator of ornithology, researches albatross specimens, looking at mercury poisoning over time in the species. Pictured in 2011, the MCZ has one of the oldest collections of black-footed albatross. The Department is a rich source of data on the environment and on the bird.
Harvard file photo
In 2020, Dennis Piechota (from left), Adam Middleton, and Joe Green work on the coffin of Ankh-Khonsu with a team at the Semitic Museum that opens ancient Egyptian coffins to analyze and photograph the coffins from all angles using scanning technology and 3D photography.
Harvard file photo
Edith Young, camera operator at Imaging Services, scans a rare Chinese book in 2010 in the digital lab in Widener Library. “The library is committed to making our collections as open as possible,” Bernier said. “And the digitization step is needed for that. There’s also materials coming in that are ‘born digital.’ So where we used to get, for example, a bunch of manuscripts from a famous author, we’re now getting laptops, we’re now getting hard drives.”
Harvard file photo
A storage space at the Museum of Comparative Zoology is pictured in 2017.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Cambridge Rindge & Latin High School students participate in hands-on activities in 2022, examining endless rows of specimens as part of Marine Science Day at the Museum of Comparative Zoology.
Harvard file photo
As the renovation of Harvard Art Museums nears completion in 2014, a woman walks past the Forbes Pigment Collection.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Jackson Kehoe, research assistant at Harvard Herbarium, displays collections in 2023 at the Harvard University Herbaria.
Harvard file photo
Stuart Heebner, collections assistant (left), and Scott Fulton, conservator, move casts to be cleaned as part of a major project in 2007 to stabilize the plaster cast collection in the Peabody Museum. Preservation can take many forms, depending on an institution’s priorities or an object’s needs. Large collections require care and efficiency. “It’s almost like you’re in a field hospital, you know, and each one has to come through your care, as gently but quickly as possible,” Bernier said. “It could be just a couple of minutes, or it could be hundreds of hours. It really depends on what it needs or why it needs it.”
Harvard file photo
Inside the Hiphop Archive and Research Institute, Makeda Daniel, media and publications coordinator, spins a record on a turntable in 2019.
Harvard file photo
Charles Orta ’16 (from left), Blake Lee ’16, Miye D’Oench ’16, and Sarah Fellay ’16 look at research materials in 2012 inside the Harvard-Yenching Library. “There’s a definite increase in interest from the faculty in object-based learning, and having students actually work with the original thing,” Bernier said. “It’s a very powerful and impactful experience to pick up a journal from 150 years ago and see what someone their age would have been saying about their experiences at Harvard or anywhere else.”
Harvard file photo
Melissa Dole (right) reletters the seat numbers in Harvard Stadium using stencils. Steve Zarba (left), who heads the two-month-long project in 2018 said, “In 1903, they did this by hand, we are trying to preserve the old look.”
Harvard file photo
Writings by Keats are pictured in 2011 in the Keats Room in Houghton Library that demonstrates cross-writing, an economical use of paper during a time when paper was valuable.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Richard Ketchen, who tends to and maintains Harvard’s clocks, is pictured in 2020 working on a clock at the Graduate School of Arts and Sciences.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Conservator of the Ware Collection of Blaschka Glass Models of Plants Scott Fulton works in 2019 to clean and restore objects from the glass flowers collection.
File photo by Stephanie Mitchell/Harvard Staff Photographer
In 2017, Dale Stinchcomb, curatorial assistant in Harvard Theatre Collection, examines a figurine by Jean-Auguste Barre of the young French ballerina Emma Livry (1842-1863) in “Le Papillon.”
Harvard file photo
The Collection of Historical Scientific Instruments disassembles the legendary Mark 1 computer in 2021 at the Science Center and transports it to the SEC, where it will be reassembled.
Harvard file photo
Sara Frankel, the collections manager for the Collection of Historical Scientific Instruments, removes years of dust from the computers’ interior mechanisms during the 2021 move.
Harvard file photo
Book conservator Katherine Beaty works in 2016 on a bound volume of business records, including partnership agreements and other related documents from the Baker Library at Harvard Business School. “It’s a complete rush,” said Bernier. “It is I think why a lot of conservators got into the field. It is an intimate process to have this item come to us from generations before, on our desk in front of us. And it’s in our hands and we have to steward it and care for it. It’s humbling as well. And exhilarating.”
Harvard file photo
Book Conservator Catherine Badot-Costello uses a microscope in 2016 to work on an illuminated, bound parchment manuscript from Houghton Library, dated 1464. Conservators preserve, repair, and save rare books and unique library materials at the Weissman Preservation Center. Repairs to objects should be unobtrusive and focus on stabilizing the object, explained Bernier. “We try to be conservative in our approach.”
Harvard file photo
In 2016, Anne Corrsin, conservation technician for Special Collections, cleans off an account book for medical services rendered by John Perkins (1698-1781) dating 1744 to 1780. Objects and collections are regularly reinterpreted and probed by new generations of scholars. A non-destructive analysis of the types of leather used to bind books, for example, could reveal new discoveries about trade routes, business, and the history of civilizations.
Harvard file photo
Nancy Lloyd, objects conservator for the Straus Center for Conservation, restores the fallen soldier statue in 2005 in the Memorial Room at Memorial Church.
Harvard file photo
Jun Imabayashi prunes a lilac plant in 2019 in the bonsai collection at the Arnold Arboretum. The meticulous pruning and care nurtures the existing plant.
Harvard file photo
The Harvard Yard Archaeology Project continues in 2021 as students participate in an excavation of the grounds in front of Matthews Hall. Patricia Capone (left) speaks with Sarah Faber ’24 as she sifts through her findings.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Robert Shure (left) and Noe Magana restore the John Harvard Statue in 2021 in Harvard Yard.
File photo by Stephanie Mitchell/Harvard Staff Photographer
How do extremists get that way? Probably quite naturally.
In new book, neuroscientist Leor Zmigrod traces connections between brain biology, political beliefs
long read
Excerpted from “The Ideological Brain: The Radical Science of Flexible Thinking” by Leor Zmigrod, Visiting Research Fellow ’19
From fascism and communism to eco-activism and spiritual evangelism, ideological groups offer absolute and utopian answers to societal troubles, strict rules for behavior, and an ingroup mentality through dedicated practices and symbols. These features exist across the spectrum of ideological persuasions. Such characteristics can emerge even when the ideology is guided by the sincerest intentions and noblest ideals — even if it claims to protect human dignity or flourishing.
Typically, ideologies are imagined as big visions. Grand and atmospheric. Intangible and out of our personal control. Few of us can outline the precise tenets of pompously uppercased Conservatism, Liberalism, Fascism, Communism, Capitalism, Racism, Sexism, Theism, or Populism, with all their myriad meanings and interpretations. As though from the heavens, these -isms describe the contours of life and prescribe human action, instructing us about the cosmos and how we ought to relate to others within it. For believers, the utopian destiny of an ideology seems carved from the clouds of eternity. A looming force soaring above our heads, meant to be venerated and revered.
The image of ideologies as celestial and static has always troubled me. Ideologies coexist among us, within us, on earth. Not in the skies of history or the towers of political elites. There is no transcendent plane on which they live; no altitudes from which attitudes descend fully formed and holy. Ideologies inhabit individuals. Individual minds convert social doctrines into ideological thinking, a style of thinking that is governed by strict mental rules and carefully regimented mental leaps.
While most definitions perceive ideologies as historical currents and sociological movements, I am interested in examining ideologies as psychological phenomena instead. This psychological lens allows us to ask what an ideology does to its believers and whom it most easily attracts. By spotlighting the processes happening within individual brains, we can probe when an ideology constrains its followers’ mental lives and whether it can ever liberate them.
I invite you to sit down on that gray chair — yes, the one at the desk — and make yourself comfortable. I point to the monitor in front of you and say this is where the experiment will happen. Soon, when I leave the room, you will see instructions pop up on the screen.
Please press ENTER when you are ready.
You press ENTER.
Hello! Welcome to the experiment. Today you will play a series of brain games and problem-solving challenges. For the first game, you will be presented with a deck of cards. Each card will be painted with a number of geometric objects of a specific color and shape. For instance, you may encounter a card with three red circles or a card decorated with a single blue triangle.
The game is a “card-sorting task.” A card will appear at the bottom of your screen. Imagine it is painted with four orange squares. You need to decide how to match it to one of four cards already at the top of the screen.
You will hear a happy jingle when you choose the CORRECT match.
You will hear an angry beep when you choose the INCORRECT match.
Please press ENTER if you understand the instructions.
You press ENTER.
Your first card has three green stars.
You try to match it with the card at the top of the screen decorated with the two blue stars. Maybe stars should go together with other stars.
BEEP!
You sigh. You try again. Maybe your three green stars should be paired with the card containing four green circles? Green-on-green?
Drag, press, release, and … happy jingles! You are right!
You shrug proudly to yourself.
Green-on-green. Easy.
Next card in your deck: one red triangle.
You follow the rule: pair color with color. You place red on red and … jackpot! Jingles again.
You like this rule. You apply it on the next round and the next. Green-on-green, red-on-red, orange-on-orange, blue-on-blue.
The habit is oddly fulfilling. Sliding cards to their rightful grouping, you barely need to think.
After five, or ten, or fifteen rounds — repetition blurs the boundaries of time — the next card in your deck has two blue squares. You go for the blue card at the top of the screen.
BEEP!
An angry, unexpected noise is emitted from the speakers.
You feel betrayed. You forgot the game world was capable of such an offensive sound. It’s insulting.
Maybe it’s just a glitch.
You select the blue card again. It’s second nature to you now, blue on blue.
BEEP!
How can this be? The game world’s inconsistency is like an astonishing infidelity. It makes you want to get up and leave the experiment room.
But you are an addict now. The jingle gave you the feeling (the illusion?) of control, of self-possession. It signaled your cleverness.
In a mad rush you drag the two-blue-squared card toward the three-orange-circled card — there is nothing unifying these cards, not number or color or shape, but you don’t care, you are annoyed. BEEP! The noise barely dissipates before you are lugging the card again, this time toward the four-green-starred card. BEEP! Outraged at this rebellion, you move the mouse in fast, frenzied motions. The rules are not supposed to change halfway through the game. You haul the card to the last unexplored option, swearing to yourself that if this isn’t a match, if the jingle doesn’t return, you will storm out of here in protest, you will wave your arm in the air to call the experimenter back in the room and demand answers, you will — jingle! It worked! You strain your eyes to see what the matching card was. It was two red triangles. Two. Two! Hah! The number of shapes on the card was the same as on the card you held. Hallelujah! Maybe order will return once more. Or maybe this iteration of the task was just a bug. A mere hiccup.
Next time a card pops up on the screen, should you obey the old tradition, follow the color code, or try this new pattern, count the numbers and sort anew? Should you stick to your guns — ignore the anomaly — or should you change, explore, adjust, adapt, revise, and realize that …
This is where I step out of the experiment and tell you that your natural reaction to the change can tell me almost everything about you. Your spontaneous response to the fact that the old rule stopped working and you needed to discover a new one to survive is a kind of inadvertent confession. In this simple game of stars and circles, you have accidentally and inevitably exposed your innermost beliefs.
Why? Because there are two of you. There is the participant who notices the change in the rule governing the game and responds by changing in line with the new demands of the task. This version of you is the adaptable, cognitively flexible individual. When the world changes, you may feel surprise, but you have no fear. You change with the times, with the demands of the environment. You are not strongly rule-bound. You are happy to slip between habits. In fact, you don’t mind having no habit at all. You easily switch between modes of thinking; you are fluid; elastic; you adapt.
However, there is another you. In this version of you, you hate the change. You notice the fact that the old rule no longer works, and you refuse to believe it. You will try again and again to repeat the first rule, but it will be in vain. In fact, you will be punished every time you repeat the original habit. The unnerving BEEP will hit you like a slap in the face. But you won’t move, won’t dodge the blow. You will remain immobile, hanging on tightly to the false belief that somehow the wrathful beep will dissipate and be replaced by a jolly melody. The false and nostalgic belief that the environment around you will magically return and so you don’t need to change. You persevere even when it would be faster to sever ties with the past and move on. This is the cognitively rigid version of you.
Which of these copies of you is you? The flexible or the rigid? The adaptable or the stubbornly unmoving?
Maybe you are neither the first nor the second. You could be somewhere in between: sometimes adaptable, sometimes rigid. Maybe your flexibility depends on circumstance. At ease, you are fluid, adjusting calmly to novelty or surprise. Yet in moments of stress, your movements narrow, your thoughts harden. Anxiety solidifies you, rendering you stiff.
What I, the experimenter, the scientist, have discovered is that how you perform in this game can give me clues about your whole approach to life. Your level of rigidity in this neuropsychological test foreshadows the rigidity with which you believe in ideologies in the social and political world. Your perceptual reflexes are linked to your ideological reflexes.
In fact, your brain comes to mirror your politics and prejudices in strange, profound, and astonishing ways — ways that challenge how we understand the tensions between nature and nurture, risk and resilience, freedom and fate. If our ideological beliefs are related to our cognitive and neural patterns of responding, then we must face new questions about how our bodies become politicized and in what ways we are capable of resisting, changing, and exercising personal agency.
When my colleagues and I invited thousands of people to complete cognitive tests of mental flexibility such as this game, called the Wisconsin Card Sorting Test, we found that the people who are the most behaviorally adaptable on neuropsychological tasks are the same people who — in the realm of ideologies — are most open-minded, most accepting of plurality and difference. The people with the most flexible minds are the people who acknowledge that the intellectual realm can be separated from the personal realm. They do not viscerally hate their interlocuters — they may hate their opinions but they do not project that hatred onto the persons voicing them. In contrast, the most cognitively rigid individuals, those who struggle to change when rules change, tend to hold the most dogmatic attitudes. They hate disagreement and are unwilling to shift their beliefs when credible counterevidence is presented.
Cognitive rigidity translates into ideological rigidity.
This may seem obvious to some: a rigid person is a rigid person. But in fact these patterns are not obvious. When neuroscientists talk about cognition and perception, we are talking about information processing that deals with simple stimuli, with basic sensory information in neutral contexts. Cognitive tasks are composed of uncomplicated elements — colored shapes and moving black dots — displayed on spare, undecorated screens. Through these tasks, we are not assessing how you deal with emotionally evocative or triggering information — information that genuinely scares you or makes you feel a sour pinch of disgust. We are not studying tasks that are too cognitively demanding or complex — ones that would exasperate you needlessly. When neuroscientists measure cognition and perception, we glean individual differences in how a brain forms decisions, learns from the environment, and responds to challenges or contradictions at the most foundational level.
These individual differences are implicit; we have little conscious access to them or control over their expression. A cognitively rigid person may insist that they are spectacularly flexible, and an adaptable thinker may believe that they lack mental malleability. It is astonishing how rarely we know ourselves.
As a result, the link between mental inflexibility and ideological rigidity reveals a critical insight about how our brains work and how ideologies penetrate human brains. It suggests that our characteristic rigidity, rigidity that is evident when we deal with any information — even orange stars and blue circles — can propagate up to higher-level rigidities that emerge in our ideological choices and actions.
Even when we are not thinking explicitly about politics, the reverberations of our ideological convictions can be felt and measured. Ideological imprints on the brain can be observed when our minds are left to roam and drift, when we imagine and invent, when we observe and interpret even the most neutral of situations. The ideological brain’s rigidities and idiosyncrasies manifest where we least expect them, in our most private sensations and physiological responses, beneath the surface of our public convictions and conscious feelings. The dangers of dogmatic ideologies are therefore not just political — the consequences are neural, individual, and existential.
Science & Tech
Experts see a ‘low information’ reversal of U.S. climate leadership
The Conemaugh Generating Station in New Florence, Pennsylvania, was slated to close in 2028. In April, President Trump signed executive orders aimed at bolstering coal mining and coal-fired power plants.Gene J. Puskar/AP Photo
Alvin Powell
Harvard Staff Writer
May 19, 2025
4 min read
Salata panelists warn of las
Experts see a ‘low information’ reversal of U.S. climate leadership
The Conemaugh Generating Station in New Florence, Pennsylvania, was slated to close in 2028. In April, President Trump signed executive orders aimed at bolstering coal mining and coal-fired power plants.
Gene J. Puskar/AP Photo
Alvin Powell
Harvard Staff Writer
4 min read
Salata panelists warn of lasting damage from executive orders and cuts to research funding
The Trump administration is attacking climate science on multiple fronts with little regard for federal law, say Harvard experts who worry that the damage will be hard to reverse even if the government eventually loses in court.
“This isn’t normal,” said Jody Freeman, the Archibald Cox Professor of Law and faculty director of Harvard Law School’s Environmental and Energy Law Program. “No president that I know of in contemporary history has ever issued executive orders that are so reckless in disregard of legal limits. They’re willing to roll the dice or intentionally violate legal requirements and then say, ‘Chase us around and sue us to stop us.’”
In April, the president signed at least two executive orders that threaten climate progress, Freeman said. One instructs the Department of Justice to investigate state climate policies that conflict with the federal government; the other calls for federal agencies to prop up the nation’s fading coal industry.
Freeman spoke at an online briefing sponsored by the Salata Institute for Climate and Sustainability. Other speakers were former Obama science adviser and Teresa and John Heinz Research Professor of Environmental Policy John Holdren; Teresa and John Heinz Professor of the Practice of Environmental Policy Joseph Aldy; and Mary Rice, the Mark and Catherine Winkler Associate Professor of Environmental Respiratory Health.
“All of this runs the risk of climate change growing faster than it otherwise would have, possibly passing catastrophic tipping points.”
John Holdren
Panelists Jody Freeman (clockwise from upper left), Mary Rice, and John Holdren with moderator Joseph Aldy.
Photo by Grace DuVal
By turning its back on climate change, the U.S. loses more than the trust of its global partners, said Holdren. It loses time in a race with very little margin for error.
“Time lost from advancing solutions is gone forever,” he said. “And all of this runs the risk of climate change growing faster than it otherwise would have, possibly passing catastrophic tipping points.”
Many of the administration’s actions seem designed to undercut our ability to understand, never mind fight, the climate crisis, Holdren said. He cited changes that have weakened the National Oceanic and Atmospheric Administration, NASA, and the National Science Foundation, along with cuts to work being carried out by nongovernmental organizations and universities. The U.S. and China have been the global leaders of efforts to better address climate change, he said. By slashing climate science, the administration is ceding leadership on an issue of global importance matched only by nuclear arms and pandemic threats, he argued.
Aldy charged that the new administration is seeking a “low information” government, with multiple actions aimed at shrinking government datasets, on climate and other issues. He is bracing for widespread negative effects touching everything from student science projects, to projections for hurricanes, extreme heat, and wildfires, to the ability of insurance companies to understand and incorporate extreme weather risks in setting rates.
“This government is actually making concerted efforts to reduce the amount of data available and reduce the generation of new data and evidence by both government scientists as well as scientists who are supported through government funding,” he said.
Aldy also lamented workforce reductions at federal agencies, including civil servants with scientific and policy expertise who will be hard to replace.
“Implementing policy is hard work,” Aldy said. “It’s critical to have a dedicated team of public servants who have the expertise and are trained in the sciences and law and public policy and public health and engineering and more. You need them to be able to understand what Congress passes, to understand what the White House may say we want to do, and then to be able to work effectively on implementation so that you can actually advance your goals.”
Rice is particularly concerned about cuts at the Environmental Protection Agency, whose research office has been slated for major changes and whose research funding to university scientists has been slashed. Philanthropy can fill some of the holes, she said, but not at the same scale or with the same consistency. Much of the affected work has direct links to human health, she noted.
“In just the past few days, the EPA has canceled hundreds of research grants to universities, to scientists,” she said, adding: “When science is silenced, lives are lost.”
William Makris, Ed.M. ’00.Photos by Veasey Conway/Harvard Staff Photographer
Campus & Community
Ready to listen
Incoming board president William Makris hopes alumni will share experiences and learn from one another
May 19, 2025
6 min read
In his role as a business school admissions officer, William Makris, Ed.M. ’00, was guided by a simple principle when interviewing candidates: listen for opportuni
Incoming board president William Makris hopes alumni will share experiences and learn from one another
6 min read
In his role as a business school admissions officer, William Makris, Ed.M. ’00, was guided by a simple principle when interviewing candidates: listen for opportunity.
“What qualities does each person bring with them?” Makris said. “How can we continue to nurture a person’s unique strengths while supporting them as they learn and grow?”
And as he prepares to step into the role of Harvard alumni board president on July 1 — a position that leads the Harvard Alumni Association board of directors and represents alumni worldwide — he is eager to listen and learn how to support and strengthen the growth of Harvard’s global alumni community.
Throughout his career, he has helped coach and advise mid-career professionals pursuing advanced degrees by being present, open to innovative ideas, and unafraid to ask questions — qualities he honed at the Harvard Graduate School of Education.
Makris has worked in various leadership roles at business schools throughout New England. He served on the admissions committee and as an adviser for the MIT executive M.B.A. program at the MIT Sloan School of Management, as associate dean of M.B.A. admissions at Babson College, and as manager of part-time and executive M.B.A. programs at Northeastern University.
“When someone shares their story, I’m going to take the time to learn deeply about this person,” Makris said. “Being curious and understanding someone’s experience is very important to me and my work with alumni.”
The promise of higher education
Higher education is deeply intertwined with Makris’ family history. The grandson of Greek immigrants who moved to Cambridge with no formal education and a hope for a better life, Makris has always had a deep connection to Harvard.
His grandfather George Culolias founded The Tasty Sandwich Shop — affectionately known as “The Tasty” — a legendary one-room lunch restaurant in Harvard Square that served generations of hungry customers from 1916 until 1997. His grandmother Penio Culolias, who lived to 102, was a driving force for her children and grandchildren to pursue higher education.
Outgoing HAA President Moitri Chowdhury Savard and Makris have worked closely during the transition.
As she brought her children to work, Makris’ grandmother walked with them through Harvard Yard. They would stop at the John Harvard Statue, where she would encourage them to study hard in the hopes that one day they could walk through the Yard as students.
Makris’ mother, Helen C. (Eleni) Makris ’50, graduated from Radcliffe College and became a teacher, and her brothers, Nicholas Culolias ’53 and Charles Bradford Ellis ’39, graduated from Harvard College. In a moment of serendipitous timing, Makris’ own graduation from HGSE coincided with his mother’s 50th reunion. His father, George “Moose” Makris, attended Northeastern University on a full football scholarship, where he also played baseball and hockey, returning to his alma mater after his official retirement to work in fundraising for athletic programs.
In today’s tumultuous time for higher education, Makris recognizes its value more than ever. “The opportunity for me to continue the journey that my grandmother envisioned is phenomenal,” he said. “I believe in the promise of higher education. I believe in what it’s done for me, and for generations of people here in the United States and in countries around the world.”
A home at Harvard
Makris, who arrived at Harvard later in life, thinks often of a quote from past HAA President Allyson Mendenhall ’90, M.L.A. ’99, who said: “Harvard comes to you when you’re ready, and you come to it when you’re ready.”
Makris earned his bachelor’s degree in public health from the University of Massachusetts, Amherst, followed by an M.B.A. from Northeastern University. Working in finance at a tech company, he pivoted to a career in higher education — finding an atmosphere that provided opportunities to give new ideas a chance, even for someone just starting out — and enrolled in the master’s degree program at HGSE.
He found “an incredible home” at HGSE. “Harvard gave me a new lens to see the world,” he said. “It adjusted my orbit. I learned how to dive deep into a topic, to be thoughtful, and to make decisions informed by data — skills I carry with me today.”
Shortly after his graduation, he was inspired to volunteer after attending an event at the Harvard Club of Boston, where he found a “commonality of intellectual curiosity, sharing, and community” among his fellow alumni across the University.
Makris served for three years as co-chair of the HGSE Recent Alumni Council before joining the Graduate School Alumni Council as co-chair. He was also the appointed director from HGSE to the HAA board for two terms, where he co-led a graduate school alumni engagement initiative and helped develop a training program for new board members. Additionally, he spent three years as vice president of University-wide alumni affairs, representing the graduate and professional Schools, followed by his current term as first vice president of the HAA.
‘Your voice will be heard’
As he approaches his term, Makris feels humbled by the privilege of representing alumni.
He has been working closely with current alumni president, Moitri Chowdhury Savard ’93, whose “warmth, genuine leadership style, and collaborative energy is a gift,” he said.
Makris is building on Savard’s concept of veritates, or many truths — embracing multiple truths in order to connect in dialogue across differences — a turn of phrase Tracy Moore II ’06 helped coin, with a new theme that emphasizes speaking from experience and listening with empathy.
“I want people to activate their Harvard voices,” he said. “If you share your knowledge and experience, it invites others to share their stories. Listening is fostered. Commonalities arise. Identification is discovered. You begin to hear others’ stories with greater empathy. You are motivated to engage in debate and dialogue.”
He wants to ensure that all alumni feel welcome to be part of the community. “Harvard is going to be there for you when you need it, no matter what age you are,” he said. “Whether you’re attending your first event ever or your first event in 20 years, you’ll find your community waiting for you, and your voice will be heard.”
As Savard has reflected on her tenure during a challenging time for higher education, she has appreciated hearing the views of alumni around the country and the world. “Alumni hold multiple truths, but agree on many shared values, including the importance of education and open inquiry,” Savard said.
She is excited to support Makris in his new role. “He understands the significance of alumni voice and brings various viewpoints to the table. His expertise in bringing people together and his positive outlook will be invaluable to the alumni community — we are lucky to have him at the helm.”
Science & Tech
‘I can just copy-paste things, so do I really need to learn?’
An AI version of Karim R. Lakhani, the Dorothy and Michael Hintze Professor of Business Administration at the Harvard Business School, delivers opening remarks at the Generative AI Symposium in a packed Klarman Hall. Photos by Grace DuVal
Sy Boles
Harvard Staff Writer
May 16, 2025
5 min read
Panelists in University-wi
‘I can just copy-paste things, so do I really need to learn?’
An AI version of Karim R. Lakhani, the Dorothy and Michael Hintze Professor of Business Administration at the Harvard Business School, delivers opening remarks at the Generative AI Symposium in a packed Klarman Hall.
Photos by Grace DuVal
Sy Boles
Harvard Staff Writer
5 min read
Panelists in University-wide symposium explore promise, peril of AI in academia
How is generative AI shaping academia? Faculty, students, and staff from across Harvard gathered recently to tackle that urgent question.
“This is an incredible opportunity for all of us, wherever we are at Harvard, to imagine how the ways in which we work, the ways in which we teach, the ways in which we learn, and the ways in which we do our research can be fundamentally transformed,” said Karim Lakhani, Dorothy and Michael Hintze Professor of Business Administration and founding chair of the Digital Data Design Institute. “Our mission of veritas can actually be enhanced by using these tools.”
“We need to be clear that access to information is not the same as learning, and it’s certainly not the same as active learning and sustained learning.”
Nonie K. Lesaux, dean of the faculty
Moderator Rebecca Nesson (left) with panelists Christopher W. Stubbs, Nonie K. Lesaux, and Iav Bojinov.
Harvard University Provost and Dane Professor of Law John Manning framed the event at Klarman Hall as a “One Harvard” moment.
The symposium surfaced disagreements about the proper use of AI in academia. Rebecca Nesson, panel moderator and dean for academic programs at the John A. Paulson School of Engineering and Applied Sciences, polled the audience: Is it OK for students to use AI to summarize the readings for a class, instead of doing the reading themselves? Is it appropriate for a professor to use AI to write a letter of recommendation? What about a first-pass assessment of student work? The audience was split.
In a panel on generative AI and the future of learning, the speakers grappled with what it means to genuinely learn something in a world shaped by AI.
“We need to be clear that access to information is not the same as learning, and it’s certainly not the same as active learning and sustained learning,” said Nonie K. Lesaux, dean of the faculty and Roy E. Larsen Professor of Education and Human Development at Harvard Graduate School of Education.
Christopher W. Stubbs, Samuel C. Moncher Professor of Physics and of Astronomy at FAS and senior adviser on generative AI, said FAS faculty vary in their adoption of AI and AI policies in the classroom: Some organize their teaching around it, while others ban it outright. “We have a long way to go in having our colleagues appreciate what this means, to rip down to the studs what it is we want to accomplish in the education we give our students, and then build it back up again,” he said.
Iavor Bojinov, assistant professor and Richard Hodgson Fellow at Harvard Business School, teaches the first AI-native course at that School, “Data Science and AI for Leaders.” Students use AI to prepare for class, answer questions, and build their own companies. “People are very positive about these tools, but it made it so easy for them to cheat. A lot of students came to me and said, ‘I can just copy-paste things, so do I really need to learn these things?’ This is something we’re thinking really hard about.”
Despite these open questions, researchers across Harvard are leveraging generative AI to achieve remarkable advancements. Alberto Cavallo, Thomas S. Murphy Professor of Business Administration and co-director of the Pricing Lab at the Digital Data Design Institute, used it to identify the countries of origin for thousands of products to estimate the impact of tariffs. Rachel Carmody, Thomas D. Cabot Associate Professor of Human Evolutionary Biology at FAS, shared AI research that combed through 40 terabytes of metagenomic data to analyze the possible extinction of certain gut bacteria in developed countries. “It’s a trillion-piece jigsaw puzzle,” she said. “With generative AI, we can get results back in a week, whereas a year ago it would have taken us a year.”
The symposium is the latest in Harvard’s efforts to elevate teaching, learning, and research through the innovative use of AI. Harvard Business School launched the Digital Data Design Institute in 2022 to be a global research center, providing data-driven insights on the ways AI is transforming work and the economy. In 2023, HUIT, in partnership with the Vice Provost for Advances in Learning, the Faculty of Arts and Sciences, and faculty and staff from across the University, launched an AI “sandbox” where users can safely play with various large language models.
The symposium finished with student presentations and a reception featuring hands-on demonstrations of AI applications. FAS, the SEAS, and the Harvard Library also co-sponsored the event.
Krista River and the Arneis Quartet.Photos by Dylan Goodman
Arts & Culture
Talking about music doesn’t have to be difficult
Clea Simon
Harvard Correspondent
May 16, 2025
4 min read
Yeats poem inspires 3 songs and deep listening, discussion at Mahindra event
Music can be difficult to talk about. But WordSong, which styles itself “Boston’s premier interactive concert organization,” con
Yeats poem inspires 3 songs and deep listening, discussion at Mahindra event
Music can be difficult to talk about. But WordSong, which styles itself “Boston’s premier interactive concert organization,” confronts the fraught relationship between music and words directly.
Earlier this month the Mahindra Humanities Center hosted a WordSong performance and discussion centered on William Butler Yeats’ “The Second Coming.” By commissioning multiple composers to set a single text to music and then inviting discussion about the poem and its varied musical settings, the series invites deeper listening of both poetry and contemporary composition.
The occasion, co-sponsored by Arts and Humanities Dean Sean Kelly, marked the premiere of short pieces by Boston-area composers Elena Ruehr, Howard Frazin, and Tom Schnauber. All three works were performed in Holden Chapel by the local Grammy Award-winning mezzo-soprano Krista River and New England-based Arneis Quartet.
“It’s difficult to talk about music, but we believe that everybody can,” said Schnauber, who founded WordSong with Frazin in 2008.
However, the German American composer added: “It is easier to talk about words than about music.”
With that in mind, the program began with a reading of Yeats’ poem. Its imagery of disconnection and a strange Sphynx-like creature waking as a moment of doom approaches, was written in 1919. That tumultuous time, following the horrific destruction of the first World War as well as Ireland’s struggles for independence, echoes into our own era, as audience members quickly noted.
As attendees chimed in about what the poem evoked for them, Schnauber jotted down themes on a white board. They included politics, disenchantment, and blame as well as religion and Einstein, whose theory of relativity was relatively new when the poem was written. Also brought up was Yeats’ animal imagery (“the falcon cannot hear the falconer”) and the poem’s structure, including its use of repetition.
A white board displays themes that the audience members said William Butler Yeats’ poem “The Second Coming” evokes for them.
Arts and Humanities Dean Sean Kelly reads the event program.
The three compositions took different approaches to the text.
Schnauber’s setting was performed first. A cappella sections, which left River’s voice exposed, were used to accentuate phrases, as when the soprano mused over the title line. Pizzicato passages played up the disconnection that is a theme of the poem.
Ruehr’s composition took a more lyrical approach. Perhaps in response to the circling falcon of the first stanza, repeated (or circling) motifs gave way to the disruption of harsh staccato passages. The music of the string quartet then turned almost dreamy for the poem’s contemplative second stanza.
Frazin’s piece started with River singing a cappella before a dramatic entrance by the strings, the instrumentals accenting the long, held vocal phrasings. This piece also made use of a few repeated motifs passed between the viola and the cello, the instrument most associated with the human voice.
After the three pieces were performed, the composers invited audience comments. Attendees remarked how different musical settings played up various emotional responses.
At times, the conversation focused on what imagery each musical piece highlighted. When Ruehr noted that the natural imagery was important to her, a listener said that had been clear in the music: “I heard the falcon swooping in yours.”
During the conversation, each piece was performed for a second time, provoking more conversation about what each composer sought to emphasize, and which were the most successful. Comments ranged from technical critiques, with some listeners saying they heard echoes of early religious or Irish folk music in the compositions, to emotional reactions.
When Schnauber and Frazin got to the monstrous “rough beast” of the second stanza, one listener noted, the effect was “cataclysmic.” In Frazin’s piece, that listener said, the effect was more “resigned.”
As the conversation turned once again to the events of Yeats’ time, Frazin emphasized how relevant the poem, and the pieces it inspired, are today.
“We’re living through a time not so unlike his time, and there are very complicated emotional conflicts,” said the composer, who also serves as WordSong’s artistic director. This raises its own questions. “Even if you don’t like something, what you are going to do about it is complicated. We are having to step back and say, how did we get here?”
As the conversation continued well past the event’s scheduled end time, it was clear that neither the text nor the music had left the audience at a loss for words.
“Listeners know a lot more than they think they do,” said Frazin. He credited people’s “intuitive artistic understanding,” an understanding that is aided by the sharing of ideas.
Photo by Dylan Goodman
Campus & Community
Bringing startup energy to whatever he does
Christina Pazzanese
Harvard Staff Writer
May 16, 2025
4 min read
Michael Oved builds community around passions for entrepreneurship, Republican politics
Part of the
Commencement 2025
series
A collection of features and profiles covering Harvard Universit
A collection of features and profiles covering Harvard University’s 374th Commencement.
Do well by doing: That’s the attitude Michael Oved, a graduating senior, says he brought to his time at Harvard College.
An economics and history concentrator with a passion for entrepreneurship and Republican politics, Oved says he takes an economics approach to projects, whether academic or extracurricular. At College, that meant identifying an unmet need and then building something new to serve that need and connect people.
“Everything I’ve done at Harvard has been about doing,” said Oved, who grew up in New York City and attended a Jewish high school in the Flatbush section of Brooklyn.
After a summer job at a startup in Barcelona, Oved wanted to bring some of that same startup buzz to Harvard and to other college students in Boston. A member of the Harvard Venture Capital Club, he envisioned an entrepreneurship summit where young aspiring VCs could meet and hear from real-world experts. Since nothing like that existed, Oved decided he’d just have to start one. Naysayers thought it was too ambitious and costly to pull off, he said, but the conference sold out and has continued for the last three years.
“I’m interested in building, I’m interested in doing, and that’s what the venture capital group was about,” he said. “It was about me using my platform as a sophomore at Harvard, an 18-year-old kid who felt like the world was at his fingertips. How can I do something with that feeling?”
Oved brought that same zeal and drive to the Harvard Republican Club, another group he joined as a first-year student looking to explore as much as the College had to offer.
“I want everyone to experience what I’ve experienced here.”
For a while, Oved kept his political views to himself. But in “Ec10,” a 500-plus student survey course taught by Harvard economists Jason Furman and David Laibson, he started speaking up in class. People took notice.
“I think people had a sense that I was asking questions from a very Republican-leaning perspective. I got dozens of people coming up to me on the street, literally, coming up to me on the street saying, ‘Michael, thank you for asking that question. I had the same question,’” he said.
Furman, Oved’s senior thesis adviser, called him “as brilliant as he is charismatic,” and said he stood out in class for his “openness to debating alternative perspectives.”
Though the cohort of Republican-leaning students on campus was thought to be small, Oved sensed there was a “hunger” for community, but no outlet where they could get together and share viewpoints. “And so, I said, how can we build something to meet that need?”
In late 2023, as president of the Harvard Republican Club, Oved grew the mailing list to 850 members and brought in high-profile speakers like tech investor Peter Thiel and Robert F. Kennedy Jr. ’76, now the U.S. Secretary of Health and Human Services.
His goal was to move the club from the campus social fringe to the center. He did just that when the club offered its full-throated endorsement of the Republican Party candidate, Donald Trump, in August 2024.
The move turned a bright, national spotlight on the club. Not long after Trump’s victory, Oved penned an essay in The Harvard Crimson, “Being Republican at Harvard Has Never Been Better,” about the need for students from across the ideological spectrum to engage in real life, not argue on the internet. But not all of the attention was welcome.
“It was a very, very difficult time for me when we endorsed,” Oved says now. Though he expected to receive some criticism for the decision, the vitriol from strangers, particularly online, was “difficult to endure.”
Still, that experience hasn’t dampened his enthusiasm for being bold and building new things. Drawing on his religious education and family values about the importance of giving back, last year Oved launched the podcast “30 Years in 30 Minutes,” where guests share life lessons from pivotal points in their lives.
“How can I bring world-class speakers that only someone from Harvard would have access to, how can I bring them to the average person?” he said of the podcast’s origin. “I want everyone to experience what I’ve experienced here.”
El Salvador President Nayib Bukele during a White House visit last month.Win McNamee/Getty Images
Nation & World
Closer look at ‘coolest dictator in the world’
Sociologist traces rise, career of Salvadoran leader some view as savior, others as authoritarian
Liz Mineo
Harvard Staff Writer
May 15, 2025
7 min read
President Nayib Bukele is both widely popular and highly controversial in
Sociologist traces rise, career of Salvadoran leader some view as savior, others as authoritarian
Liz Mineo
Harvard Staff Writer
7 min read
President Nayib Bukele is both widely popular and highly controversial in El Salvador.
But he was less well-known in the U.S. until his visit to the White House in April to underscore his cooperation with the U.S. government’s plan to send some migrants to El Salvador for imprisonment.
Born to a wealthy family of Palestinian ancestry, Bukele has won supporters in El Salvador due to his widespread crackdown on the nation’s powerful criminal gangs with an “iron fist” policy. Critics say he has also trampled constitutional rights and civil liberties and seeks to curtail press freedoms.
In this edited interview, Professor of Sociology Jocelyn Viterna, who has researched El Salvador for over 30 years, spoke about Bukele’s rise to power and her concerns over his methods.
Before Bukele ran for president in 2019, he had been mayor of a small suburb near San Salvador and then mayor of San Salvador. He identified himself as a left-wing politician who ran on an FMLN (a former rebel group) ticket, but he grew frustrated with the FMLN just like many people in the country.
By the end of his term as mayor of San Salvador, he had become an independent politician. He formed his own party, Nuevas Ideas, and began adopting a populist image — that he was neither right nor left, but something new. Originally, he framed himself as being heavily invested in the development of El Salvador through people, the economy, and especially through tourism. But since 2022, with a crackdown on gang violence in El Salvador, he’s adopted a much more authoritarian identity.
Can you talk a bit more about what that looks like on the ground?
Between Bukele’s controversial second term in 2024, which he accomplished after packing the Supreme Court with loyalists who ruled that he could run despite constitutional limits, and the continuing state of exception, we have seen a complete override of democratic checks and balances. That includes attacks on the media, and his willingness to jail people who oppose his policies or whom he sees as not sufficiently loyal.
People now feel a sense of security; they can go out at night, because Bukele has reduced gang violence in El Salvador. But they are also scared to talk freely. I used to do interviews in El Salvador in the late 1990s and early 2000s, shortly after the civil war, and I never found anyone who wouldn’t talk to me frankly about their political beliefs or what they thought about the government. Now, everyone, from doctors to lawyers to politicians, is afraid of saying anything critical of the government.
What also worries me is that the state of exception, which suspended civil liberties and due process, is leading to a lot of other crimes not being reported. For example, reports suggest that police are increasingly using extra-legal violence, yet nobody reports it because nobody wants to be thrown in jail.
“It’s hard to overstate how frustrated the country was with the two main political parties, with the corruption that both of them engaged in, and especially with the very high rates of violence.”
Bukele has an over 80 percent approval rating in El Salvador. Why is he seemingly so popular?
There’s a number of reasons. First, when Bukele ran for president, many people on the left and the right saw him as someone who represented a way forward, different from a traditional politician. It’s hard to overstate how frustrated the country was with the two main political parties, with the corruption that both of them engaged in, and especially with the very high rates of violence.
The second reason why people love Bukele is that he has reduced both gang violence and murder rates in El Salvador. Gangs used to control large swaths of the country and were very brutal; many people lost their lives, their children, and their properties. Now people have safety, security and freedom from the gang violence that they have not had in over two decades.
And the third reason is that Bukele is a master of publicity. He is very adept at using social media, and he’s passed laws that have reduced the ability of media outlets to speak out against him. When you have that kind of complete control of the narrative, you often paint a picture that helps maintain your popularity.
El Salvador had one of the highest murder rates in the continent due to the violent criminal gangs. How did Bukele manage to control them?
There are a lot of unanswered questions, but what our own U.S. Department of Justice has reported is that early in his first presidency, Bukele engaged in illegal negotiations with the gangs to keep the violence down.
Bukele has denied this, but there is some evidence of his dealings with the gangs. One example is that in March of 2022, the gangs allegedly felt that Bukele was not holding up his end of the negotiations and went on a massive killing spree. They killed 87 people in one weekend — the highest number of people killed in El Salvador since the civil war in a single day.
Some media outlets report that this gave Bukele the impetus to crack down on the gangs; he passed a state of exception that was supposed to last 90 days, and it is now in its third year.
In the sweeps that followed, somewhere between 80,000 and 90,000 additional people were put into prison in El Salvador and Bukele’ s own government said that at least 8,000 innocent people were caught up in those sweeps. Because of the state of exception and lack of due process, it’s unclear whether and how these individuals will get out of jail.
Why is Bukele cooperating with the Trump administration on immigration?
Bukele has thrived on using a policy of “mano dura,” presenting himself as a strong-handed leader who is going to fix problems quickly and effectively and won’t take no for an answer. I think that to have the opportunity to highlight what he’s done in El Salvador from the White House was something that was difficult to resist for him.
What do Salvadorans think about Bukele’s imprisoning deported migrants from the U.S.?
I’ve been surprised at how positive they have been about it, at least in social media. I find this surprising because the Salvadoran diaspora, mostly those living in the United States, is responsible for holding up the economy that Bukele is running.
I’m very bothered by the fact that Bukele, the first Salvadoran president who’s ever gotten invited to the White House, did not take advantage of the opportunity to ask for an extension of TPS [Temporary Protected Status, which allows immigrants from troubled nations to live and work in the U.S.] or a sort of work-exchange program, or even to advocate for the migrants in the U.S., but instead laughed and made jokes about Kilmar Abrego Garcia, who was picked up by mistake by ICE and was sent back to El Salvador.
Health
Do ultra-processed foods increase Parkinson’s risk?
Alberto Ascherio, professor of epidemiology and nutrition at the Chan School of Public Health.Stephanie Mitchell/Harvard Staff Photographer
Anna Gibbs
Harvard Correspondent
May 15, 2025
7 min read
New study finds people who consume higher servings are more likely to show early signs of the disease
More than half of the average Am
Do ultra-processed foods increase Parkinson’s risk?
Alberto Ascherio, professor of epidemiology and nutrition at the Chan School of Public Health.
Stephanie Mitchell/Harvard Staff Photographer
Anna Gibbs
Harvard Correspondent
7 min read
New study finds people who consume higher servings are more likely to show early signs of the disease
More than half of the average American adult’s calories come from ultra-processed foods, which have minimal nutritional value and often contain artificial additives. A growing body of research suggests that eating large amounts of such foods may raise the risk of various chronic diseases. New evidence links high consumption with greater likelihood of developing features that precede Parkinson’s disease.
Researchers at Fudan University in Shanghai, China, in collaboration with Alberto Ascherio at the Harvard T.H. Chan School of Public Health, worked with the self-reported diet data from more than 40,000 health professionals, tracked since the mid-1980s. In the 2010s, the participants also answered questions about early nonmotor features associated with Parkinson’s.
Comparing these data points, the team found that people who consumed about 11 servings of ultra-processed foods per day were 2.5 times likelier to develop early nonmotor features than people who consumed about two to three servings.
In this edited conversation, Ascherio explains the significance of the finding and what’s still unknown.
Going into this study, what’s the understanding about how diet can affect brain health, particularly neurodegenerative diseases like Parkinson’s?
There’s no question that diet is important. In fact, there’s a consensus that we could delay the onset of many neurodegenerative diseases by being physically active and having a healthy diet. But there is still a lot that we need to understand, particularly when it comes to Parkinson’s, which is a bit of an exception among chronic diseases. For instance, cigarette smoking is associated with a lower risk of Parkinson’s — it’s one of the very, very few diseases in which cigarette smoking doesn’t raise the risk of the disease. With diet, it’d be nice if the diet that delays cardiovascular disease or cancer also contributes to prevent Parkinson’s. But we don’t know yet.
We do know a few things. We’ve previously found that caffeine intake is associated with a lower risk of Parkinson’s disease. There’s evidence that the Mediterranean diet, which is associated with lower risk of many chronic diseases, might do the same for Parkinson’s, but it’s not as clear as with cardiovascular disease or diabetes. And we’ve seen that intake of flavonoid, which is a component of fruits and vegetables, also tends to be modestly associated with lower risk of Parkinson’s. I think we’re still missing something. In this study with ultra-processed food, though, we found much stronger signals than we’ve seen before.
Why did you focus on early symptoms, as opposed to people who developed Parkinson’s? And why ultra-processed food?
Parkinson’s disease really starts at least 10 to 15 years before the diagnosis. If you study individuals with diagnosed Parkinson’s disease, you’re really 15 years late. So we wanted to find out which factors may influence the development of Parkinson’s disease. For this purpose, we created this large cohort in which we assess the presence of what we call prodromal features of Parkinson’s disease, which occur many years before the typical signs and symptoms of the disease.
In terms of the dietary aspect, we’ve been studying nutrient and dietary patterns for many years, but more recently, it became of interest to look at food in terms of the amount of processing and artificial ingredients. Food processing has always been a necessity for preservation and shelf life, but we’re talking about something different with ultra-processed food. This is really an industrial process to make the food more attractive. It goes well beyond what is needed to preserve the food and is more related to the marketing and commercial aspects of the food industry.
Which prodromal features, or early signs, did you focus on?
We had a huge cohort, so we selected from the clinical literature those common prodromal features that are relatively easy to assess with just simple questions or inexpensive tests. One feature was acting out dreams, which we only asked of people who had a sleeping partner who could verify it. Another was hyposmia, or reduced sense of smell. For that, there was a scratch-and-sniff test that we mailed out for people to smell. And also intestinal constipation, a non-specific feature that can be significant when combined with other signs.
Obviously when you look at these features one by one, they are very common, but the combination of three or more is present in only about 2 percent of older adults. We’ve found in past research that people with all three of these features are 23 times more likely to develop Parkinson’s disease.
“Will eating less of these foods be sufficient to prevent Parkinson’s? Almost certainly not, but it could be beneficial. So far, the strongest evidence for reducing Parkinson’s risk is for physical activity.”
You found an association, but not necessarily a cause. How likely is it that the ultra-processed food is causing the development of the prodromal features?
It is very challenging. There’s always the risk of reverse causality, where the prodromal features influence the diet, rather than diet influencing the prodromal features. For instance, if you’re constipated, you might eat more fruits and vegetables to offset the constipation. But we tried to address this by looking at diet very early on. We started assessing the prodromal features in 2012, and we found that there’s already an association between those features in 2012 and the diet back in 1986. In other words, if you have high consumption of ultra-processed food in 1986, you’re more likely to have these prodromal features in 2012. If it was reverse causation, you wouldn’t expect an association to be present that early.
The other limitation is what we call confounding: Could the consumption of ultra-processed food be a marker or something else? We try to adjust for other factors, but the adjustment is never perfect or complete. We do not know yet whether there’s something toxic in the ultra-processed food, or maybe, given that they contribute to 50 percent or more of your calories, you’re just missing other components of the diet that are protective.
If ultra-processed food is the cause, what might the mechanism be?
We don’t really know. But there is evidence that some chemicals can cause Parkinson’s disease. The evidence is particularly strong for pesticides and herbicides. It’s clear that they can increase risk; we just don’t know which pesticides do that. This is because we are exposed to combinations of pesticides and herbicides, not to individual compounds.
Here, we are in a similar situation. We can see that this ultra-processed food is associated with a higher frequency of these prodromal features, but we really don’t know which component. And, as I mentioned, it could even be a displacement of nutrients rather than a specific toxic effect.
What should people do with this information?
Well, given the accumulated evidence related to risk of cardiovascular disease, diabetes, chronic decline, and dementia, there’s no question that we should limit consumption of ultra-processed foods as much as possible. And it seems that Parkinson’s is in the same direction. Will eating less of these foods be sufficient to prevent Parkinson’s? Almost certainly not, but it could be beneficial. So far, the strongest evidence for reducing Parkinson’s risk is for physical activity. I know it’s a bit disappointing to not have a clear answer. It’s a very difficult question to address, but it’s one that we’ll continue to study.
This research was funded in part by the NIH National Institute of Neurological Disorders and Stroke and the Department of Defense.
Health
‘Smoldering’ cardiovascular crisis
Photo illustration by Liz Zonarich/Harvard Staff
Jacob Sweet
Harvard Staff Writer
May 15, 2025
9 min read
Downward trend in deaths appears stalled due to lack of urgency among doctors, patients, along with healthcare barriers
Starting in the late 1960s, cardiovascular disease deaths fell and fell. Mortality decreased by 70 percent — from 206 deat
Downward trend in deaths appears stalled due to lack of urgency among doctors, patients, along with healthcare barriers
Starting in the late 1960s, cardiovascular disease deaths fell and fell. Mortality decreased by 70 percent — from 206 deaths per 100,000 in 1968 to 62 deaths in 2017. The share of all premature deaths attributable to heart disease fell, too.
The trends no longer look so promising. Around 2010, the long decline in cardiovascular deaths began to level off and appear stalled. Somestudiesfind that they’re increasing year over year for the first time since the 1950s.
Scientific innovation hasn’t stopped. Fundamental research has led to new drugs, treatments, and interventions. Public health campaigns warn against smoking, and some of the most powerful drugs to treat high blood pressure and high cholesterol — two major, common risk factors —are widely available and cheaper than ever. Those who actually suffer a heart attack survive more than 90 percent of the time.
But, health professionals say, greater awareness of the urgency of the problem is needed. Too many ignore lifestyle practices like healthy diets and regular exercise, and medical professionals need to be more aggressive about preventive care. In addition, there are deficiencies in the healthcare system itself. Working on all of this, along with continued innovation, is viewed as key to getting the nation back on track.
Heart disease is a lifelong struggle. For Rishi Wadhera, a cardiologist at the Beth Israel Deaconess Medical Center and associate professor of medicine at Harvard Medical School (HMS), the problems start with young people. “I call it a smoldering crisis,” he says.
Wadhera researches heart health in younger adult populations and finds that they’re putting more stress on their hearts. In a paper published in the journal JAMA, Wadhera and his colleagues found that between 2009 and 2020, people between 20 and 44 saw increases in diabetes (3 percent to 4.1 percent), obesity (32.7 percent to 40.9 percent), and hypertension (9.3 to 11.5 percent).
These risk factors lead to earlier heart attacks. In the European Heart Journal, Wadhera and colleagues reported that heart attacks for people between 25 and 64 rose from 155 per 100,000 people to 161. This cohort of adults also suffered more instances of heart failure (from 165.3 to 225.3 per 100,000) and ischemic strokes (76.3 to 108.1 per 100,000).
Wadhera called the report “alarming.” In lower-income communities, cardiovascular hospitalization rates among younger adults were two to three times larger than in their high-income counterparts. Black Americans fared particularly poorly; about 40 percent of hospitalized younger adults from low-income communities were Black. These disparities did not narrow over time.
Plenty of progress has been made over the last few decades. Of the total number of premature deaths in the U.S., nearly 39 percent of them were heart-disease related in 1980. Today, that number is 20 percent. Overall rates of premature deaths related to cardiovascular disease is down about 70 percent since its 1968 peak.
Still, heart disease remains the leading cause of death for Americans.
Cardiologists believe public-health campaigns will be critical to lowering heart disease — from increasing awareness of new treatments, to focusing on prevention, to simply raising awareness of the risk of heart disease in the U.S.
The last factor, says Michelle O’Donoghue, McGillycuddy-Logue Endowed Chair in Cardiology at Brigham and Women’s Hospital, is still not common knowledge. “There’s this misconception that cancer — in particular, breast cancer — is what women need to hear about the most when it comes to conditions that may affect them in their lifetime,” she said. “But in fact, cardiovascular disease remains, unfortunately, the No. 1 killer of both women and men.”
This lack of awareness has downstream effects. O’Donoghue, who is also associate professor of medicine at HMS, has found that women are likely to be undertreated when it comes to heart disease compared to men. They’re also less likely than men to correctly identify symptoms of a heart attack, which can sometimes vary by sex.
Michelle O’Donoghue and Rishi Wadhera are among the many Harvard-affiliated specialists working to raise awareness about the persistent threat posed by heart disease.
Niles Singer/Harvard Staff Photographer
Stephanie Mitchell/Harvard Staff Photographer
The most common symptom in both men and women is chest tightness or heaviness, with women more likely to experience accompanying dizziness, nausea, and fatigue. But even presenting the same symptoms, O’Donoghue says, women are likelier to be ignored.
This lack of attention paid to heart disease in both men and women, O’Donoghue argues, makes it easier for patients — and doctors — to perpetually delay treatment. “Your primary care doctor may say, ‘Your blood pressure is a little high. Let’s check it again next time,’” said O’Donoghue. “And, you know, that inevitably keeps happening.”
That’s if people have access to a doctor at all. Wadhera says there are still significant barriers for preventative screenings. “If you look at Boston right now, it’s very hard to get an appointment to see a primary care doctor,” Wadhera said. “And if you don’t have access to a primary care provider, how are you supposed to receive important preventive screenings and care?”
The barriers continue from there. “Even if you have coverage, copay or deductibles may be high, creating barriers to obtaining testing and treatments that mitigate the risk of developing heart disease, heart attacks, or stroke.” For those who need more powerful drugs than statins, the cost can be insurmountable.
Due to the slow-burn nature of heart disease, the barriers to screenings, and the limited attention paid to preventative care, patients don’t always follow medical advice or use their prescriptions. According to a 2023 paper in the Annals of Internal Medicine, the use of statins jumped from 11.6 percent in 1999-2000 to 33.6 percent in 2013-2014 by guideline-eligible patients, and have since stagnated.
Today, only about one-third of patients eligible to take statins actually do so. “If we could get that number up closer to 100 percent,” said Wadhera, “we could probably make a huge dent in reducing cardiovascular risk and improving cardiovascular outcomes at the population level.”
“Cardiovascular disease remains, unfortunately, the No. 1 killer of both women and men.”
Michelle O’Donoghue
Most doctors argue that even with new treatments, implementation remains an issue.
“In a large healthcare system, there is just inertia,” says Marc Sabatine, the Lewis Dexter M.D. Endowed Chair in Cardiovascular Medicine at Brigham and Women’s Hospital.
For Type 2 diabetes, for example, Sabatine notes that many patients remain on older drugs that may control blood-glucose levels but would be better off taking drugs that also have been proven to reduce the risk of adverse heart outcomes.
It can be difficult for a doctor to say, “Even though you feel OK, we have data to suggest that we should change your medical regimen,” says Sabatine — especially because the first time a patient may feel the effects of dealing with risk factors could be sudden cardiac death.
But these sorts of proactive shifts could be crucial to improving heart health. Sabatine points to LDL cholesterol — also known as “bad” cholesterol — as a risk factor that doctors could target more aggressively. While doctors generally consider 100 mg/dL a healthy level of LDL cholesterol in the blood, Sabatine argues the standard should be lowered to about 70 mg/dL, the point at which arterial plaque begins to actually decline.
In all, Sabatine thinks the way the U.S. deals with heart disease is inadequate.
“Periodic visits with a primary care physician is a relatively inefficient way to do it,” he said. Instead of cramming preventative care into a few minutes a year with a physician, argues Sabatine, it has been shown that medical systems can train nurse practitioners and pharmacists to measure patients’ risk factors more frequently and adjust medications as needed under the supervision of physicians.
But while doctors see plenty of room to improve with the current, accessible medications, they see promise in the state of drug development.
“It used to be that we had a very small arsenal of drugs available to us,” O’Donoghue said. But the possibilities are growing. GLP-1 receptor agonists — originally developed to treat diabetes — can help people lose weight and improve heart health.
Verve Therapeutics, founded by former HMS professor Sekar Kathiresan, is running Phase 1b trials on gene-editing therapies that could lower cholesterol by rewriting DNA instructions in liver cells that control cholesterol production. New scientific developments carry not only the potential to treat symptoms, but also to address some of the logistical limitations of existing heart-disease treatment.
New scientific developments carry not only the potential to treat symptoms, but also to address some of the logistical limitations of existing heart-disease treatment.
O’Donoghue herself is working on a drug with the pharmaceutical company Amgen that significantly lowers lipoprotein(a) concentration in the blood. Though this form of cholesterol is about 90 percent genetically predetermined — especially high for people of African and South Asian descent, as well as for women after menopause — there is no current treatment.
As a graduate student in Andrew Kruse’s lab, Sarah Erlandson figured out the structure and function of RXFP-1 receptor, which interacts with the hormone relaxin to dilate blood vessels, boost blood flow, break down collagen in the heart, and reduce inflammation — effects that could make it a powerful target for treating heart failure.
After mapping how the receptor functioned, Erlandson teamed up with Kruse, the Springer Professor of Biological Chemistry and Molecular Pharmacology, to design a new therapeutic that mimics the hormone’s beneficial effects but lasts much longer in the body. Harvard’s Blavatnik Biomedical Accelerator provided funding and business development support to advance the technology toward commercialization.
With help from Harvard’s Office of Technology Development (OTD), the University patented the new molecule and licensed it to Tectonic Pharmaceuticals, a company Kruse founded. Fewer than five years after the original prototype, Tectonic is now testing an updated version of Erlandson’s molecule in Phase 2 clinical trials.
Other technologies aim to treat other advanced stages of heart disease. With funding support from Harvard’s Blavatnik Biomedical Accelerator, stem cell and regenerative biology professor Richard T. Lee and engineering professor Jia Liu are co-developing a flexible, tissue-like device designed to both detect and stop atrial fibrillation — an irregular heart rhythm that can lead to stroke and heart failure. “If you could stop it before it gets going, then you really have something,” Lee said.
“We’ve made good progress,” Sabatine said, “and we should celebrate the progress we’ve made.” But with rates remaining as stubborn as they have been in half a century, Sabatine and his colleagues are committed to searching for novel ways to get better treatment for more people. “We need to continue to drive rates ever downward,” he said.
Illustrations by Liz Zonarich/Harvard Staff
Science & Tech
Strange galactic facts
Sy Boles
Harvard Staff Writer
May 15, 2025
1 min read
Test the limits of your cosmic IQ by taking our quiz based on Harvard astronomy research
There’s nothing quite like looking up at the sky on a dark night and catching a glimpse of the path of light we know as the Milky Way. More than 400 years a
Test the limits of your cosmic IQ by taking our quiz based on Harvard astronomy research
There’s nothing quite like looking up at the sky on a dark night and catching a glimpse of the path of light we know as the Milky Way. More than 400 years ago, Galileo viewed the Milky Way through a rudimentary telescope and determined that it was made up of innumerable individual stars. Today we know much more about our own galaxy and countless others, but major questions remain unanswered.
Scientists at the Center for Astrophysics | Harvard & Smithsonian are researching some of our biggest questions about galaxies. We asked CfA researcher and Harvard Ph.D. student Vedant Chandra to help develop this quiz about what we know so far, and what remains to be discovered.
Research from the CfA is supported by the Smithsonian, a federally funded trust.
Raymond Mak (left) and Hugo Aerts.Stephanie Mitchell/Harvard Staff Photographer
Health
New AI tool predicts biological age by looking at a face
Deep-learning algorithm FaceAge uses snapshots, can help oncologists tailor treatments
Alvin Powell
Harvard Staff Writer
May 15, 2025
5 min read
A new artificial intelligence tool developed by researchers at Mass General Brigham and Harvard Medica
New AI tool predicts biological age by looking at a face
Deep-learning algorithm FaceAge uses snapshots, can help oncologists tailor treatments
Alvin Powell
Harvard Staff Writer
5 min read
A new artificial intelligence tool developed by researchers at Mass General Brigham and Harvard Medical School uses a snapshot of a patient’s face to predict biological age and cancer survival time, knowledge that physicians can use to tailor treatments.
“We all know that people age in different ways. A person’s chronological age is based on the day they were born, but it’s not the same as biological age, which is actually a predictor of their physiological health and life expectancy,” said Hugo Aerts, the study’s co-senior author, director of MGB’s Artificial Intelligence in Medicine program, and professor of radiation oncology at HMS. “A person’s biological age is dependent on many factors, like lifestyle, genetics, and other health factors. We had this idea that how old a person looks could actually be a reflection of their biological age.”
Led by scientists at MGB’s Artificial Intelligence in Medicine Program, the researchers trained FaceAge, their deep-learning algorithm, on more than 58,000 photos of healthy individuals of known age and on more than 6,000 photos of cancer patients whose age and clinical outcome was known.
The algorithm indicated that cancer patients’ FaceAge averaged five years older than their chronological age. It also found that looking older was associated with worse outcomes for patients suffering from several cancer types.
“We had this idea that how old a person looks could actually be a reflection of their biological age.”
Hugo Aerts
Judging one’s health according to appearance is nothing new, Aerts said. Doctors routinely make a visual assessment — the “eyeball test,” Aerts called it — when they walk in the room. It can encompass things like whether the patient is in a wheelchair, how robust they look, and whether they’re obviously ill.
The research showed, however, that the eyeball test — at least when performed by human physicians — is not a very good predictor of short-term life expectancy.
Published in the journal The Lancet Digital Health in early May, the study, which received funding from the National Institutes of Health, asked 10 clinicians and researchers to predict short-term life expectancy using photos of 100 terminal patients who were receiving palliative radiation therapy.
On average, they performed only slightly better than random chance, even when they knew things like the patient’s chronological age and the status of their cancer. Prediction improved, however, when the physicians were provided with FaceAge information for those patients.
Raymond Mak, a faculty member at the Artificial Intelligence in Medicine Program, HMS associate professor of radiology oncology, and co-senior author of the study, said having a better understanding of a patient’s biological age and how much time they likely have remaining allows oncologists to better tailor treatments.
He described a lung cancer patient who, though chronologically 86, looked considerably younger. That was a factor in Mak suggesting more aggressive treatment. Today, the man continues to do well at age 90. When Mak used FaceAge to analyze a photo of the patient at the time of treatment, the algorithm put his biological age as 10 years younger than his chronological age.
The opposite can also be true, Mak said, and patients who are frailer than their chronological age might suggest may need less-intensive treatment because that’s what their body can tolerate.
“We hypothesize that FaceAge could be used as a biomarker in cancer care to quantify a patient’s biological age and help a doctor make these tough decisions,” Mak said.
FaceAge has proved effective across several different types of cancer, Mak and Aert said, and they’re exploring its potential usefulness to predict outcomes in other diseases.
The algorithm employs deep learning, which means that it learns as researchers train it on thousands of photographs of people whose outcomes are known.
Researchers, however, don’t know which specific cues draw FaceAge’s focus, Aert said. It’s likely the algorithm is picking up on different things than a doctor might, such as wrinkles, gray hair, and baldness. If that’s true, that would make it particularly useful, he said, because it brings a different perspective to the physicians’ analysis of the patient’s condition.
Aerts and Mak said FaceAge would not be used on its own to determine courses of action but rather would be a tool available to physicians. It could not only help to determine initial treatment, but it could also monitor changes over time, alerting a doctor if a patient appears to be going downhill.
Before it is used in the clinic, however, it needs additional testing on diverse patient populations.
“In the clinic, the impact can be very large, because we now have a way to actually very easily monitor a patient’s health status continuously — before, during, and after treatment — and this could help us to better predict the risk of complications after, for example, a major surgery or other treatments,” Aerts said.
Health
Why the Achilles is such a danger zone
Boston Celtics star Jayson Tatum clutches his foot in pain after an injury during Monday’s playoff game vs. the New York Knicks.Getty Images
Christina Pazzanese
Harvard Staff Writer
May 14, 2025
5 min read
With Jayson Tatum facing long road to recovery, surgeon explains force behind injury, how it’s repaired
When Boston Celtics superstar Jays
Boston Celtics star Jayson Tatum clutches his foot in pain after an injury during Monday’s playoff game vs. the New York Knicks.
Getty Images
Christina Pazzanese
Harvard Staff Writer
5 min read
With Jayson Tatum facing long road to recovery, surgeon explains force behind injury, how it’s repaired
When Boston Celtics superstar Jayson Tatum dropped to the ground and grabbed his right foot in agony during Monday’s playoff game against the New York Knicks, fans feared the worst.
They weren’t wrong to panic. On Tuesday, the team announced that Tatum had undergone surgery to repair a ruptured Achilles tendon. He will miss the rest of the playoffs and possibly all of the 2025-2026 season.
In this edited conversation with the Gazette, George Theodore, a Medical School alum and an orthopedic surgeon at Mass General Brigham, explains why the Achilles tear is the injury that athletes dread most. Theodore is a foot and ankle consultant for Harvard’s men’s and women’s athletics and treats patients on local professional teams, including the Boston Red Sox, for whom he is team physician, as well as the New England Patriots and Boston Bruins.
How does an Achilles tendon rupture?
Number one, it’s important to know that it’s the largest tendon in the body, and as a result, it’s very important in sports and in recreation for push-off. When there’s a forceful movement down at the Achilles or the ankle area, such as a dorsiflexion, it can trigger an injury. Also, the area where it ruptures has a low blood supply compared to other areas of the body. So there’s already a low blood supply and then combined with a very forceful flexion of the ankle, these two things injure the Achilles. Often we don’t know why this has happened. Athletes can have risk factors for the injury, but it’s very difficult to prevent.
The achilles tendon is the “largest tendon in the body,” says Mass General Brigham orthopedic surgeon George Theodore, making it key in sports for “push-off” and vulnerable to injury.
Getty Images
Tatum seemed fine up until the moment it happened. Is it possible that a small pre-existing injury can contribute to a rupture?
We know that in older patients who get Achilles tendon ruptures — we see this a lot in pickleball and tennis — often there’s longstanding tendon damage. In younger patients, the rupture is usually from a forceful injury. It’s possible that they’ve had some pre-existing issues in there, but that’s not as common as with the older athlete.
A tear can mean everything from a strain — a little stretch — to a partial tear to a complete tear. A rupture is a complete tear. A strain is usually treated with a period of rest followed by rehabilitation. A partial tear is also something that’s usually not treated surgically, but with rest and rehabilitation, and usually with successful return to sport. The rupture is the most serious. That has the most important decision-making over whether to fix it or not to fix it, and then implications for how the patient will do down the line.
How is the Achilles repaired during surgery?
During the surgery, the two ends are brought together and fixed with suture. And this can be done either through an open incision or a mini percutaneous incision: You can use an open incision to bring the two ends together, or sometimes we pass sutures through the skin and then just tie the two ends together under the surface.
Is surgery the only option to repair a rupture?
In certain groups, we can treat ruptures non-operatively with good results. Those tend to be patients whose demand to return to a high-energy, push-off lifestyle may not be as great. It may also be patients who are not healthy enough to undergo surgery. There may be patients who, for example, are only interested in doing normal walking and low-impact activities. They can be successfully treated non-operatively. That involves a different protocol. Sometimes we put them in a cast or a boot with heel lifts, followed by a physical therapy program.
What’s the typical recovery time and protocol for people like Tatum, who had surgery after a complete Achilles tear?
There will be a time where the patient will be immobilized. That is to say, they’ll have a short time and a cast to allow the incision to heal. After that, they’ll be allowed to bear weight in a walking boot, and then they’ll be allowed to start a comprehensive rehabilitation program. The return to sport for someone at his level is approximately nine to 12 months. Studies have shown that 80 percent of elite athletes eventually get back to their previous level of performance.
How does recovery today compare to five or 10 years ago — have there been any significant advances?
I think the three main advances are: 1. More minimally invasive surgery or smaller incisions; 2. A more aggressive rehabilitation program so that people are bearing weight earlier, starting to move the ankle earlier, and getting into physical therapy earlier; 3. Testing that shows what patients’ limitations are, which gives us the ability to see those limitations — functional, physical, and psychological — and get patients back to where they want to be. That involves a lot of resources and a lot of people. It involves the surgeon, the patient, the physical therapist, and the psychologist.
Health
Tips for staying alive, decades in the making
JoAnn Manson has spent her career researching – and highlighting – how everyday choices influence health
Alvin Powell
Harvard Staff Writer
May 14, 2025
5 min read
JoAnn Manson.Veasey Conway/Harvard Staff Photographer
Part of the
Profiles of Progress
series
When it comes to the idea that preve
When it comes to the idea that prevention is the best medicine, JoAnn Manson doesn’t mess around.
Since the 1980s, Manson has dedicated her career to teasing out complex threads of human health, with an emphasis on factors under our control: physical activity, diet, sleep, smoking, alcohol consumption, medications such as menopausal hormone therapy, low-dose aspirin, statins, and, most recently, vitamins and other dietary supplements.
“Ever since my early years of medical training, I’ve been astounded by the powerful role of modifiable lifestyle factors as bulwarks against chronic disease,” said Manson, who is the Michael and Lee Bell Endowed Professor of Women’s Health at Harvard Medical School, chief of the Division of Preventive Medicine at Brigham and Women’s Hospital, and a professor of epidemiology at the Harvard Chan School. “I became motivated to devote my research career to testing interventions to reduce chronic disease burden, extend years of good health or ‘healthspan,’ and to try to decrease premature mortality.”
“Ever since my early years of medical training, I’ve been astounded by the powerful role of modifiable lifestyle factors as bulwarks against chronic disease.”
A scan of Manson’s publication history — one major database of medical research returns more than 1,800 hits on her name — reads like a list of national health headlines over the past 20 years: menopausal hormone therapy and cardiovascular disease and breast cancer; passive smoking in the workplace; walking versus vigorous exercise in prevention of heart disease; steps per day and cancer risk; pre-pandemic physical activity and COVID severity. A member of the National Academy of Medicine, she is listed by Research.com as the world’s top female scientist based on citation metrics, with more than 369,000 citations and an h-index, which reflects the scope and influence of her work, of 310.
Her tools have been major randomized prevention trials and large longitudinal studies that follow tens of thousands of people over time, gathering health, diet, and behavioral data, often augmented by blood, tissue, and other physical samples that enrich the picture and provide physical evidence of changes reported by participants. Many of these initiatives have received support from the federal government.
Manson’s research began with the landmark Nurses’ Health Study, which launched in 1976, when most study subjects were white males, and sought to fill gaps around women’s health. The decadeslong study, established by Brigham and Harvard investigators to explore links between contraceptive use, smoking, heart disease, and cancer, expanded over time to provide a broad view of lifestyle and health. Manson has been involved with the project since the mid-1980s and has been a principal investigator of the cardiovascular component for 26 years.
In 1993, Manson became one of the initial principal investigators of a National Institutes of Health-backed study called the Women’s Health Initiative, which enrolled 160,000 postmenopausal women in three large, randomized trials, along with an investigation of major causes of chronic disease and mortality in older women, including cardiovascular disease, cancer, and osteoporosis. Manson leads the study’s clinical center in Boston.
More recently, she has focused on what she has described as the “Wild West” of American healthcare — dietary supplements, whose health claims and distribution are unchecked and unregulated. In the nationwide VITAL randomized trial of 25,000 men and women 50 and older, she and colleagues investigated health claims about vitamin D and omega-3 fatty acids, reporting in 2018 that omega-3 fatty acids in fish oil were associated with a 28 percent reduction in heart attack. The effect was even higher among those who reported minimal fish in their diet, cutting risk about 40 percent. For vitamin D, there appeared to be little effect on heart disease, but a significant 17 percent reduction in advanced cancer, and a 22 percent reduction in autoimmune diseases.
A more recent randomized trial, COSMOS, the COcoa Supplement and Multivitamin Outcome Study, investigated links between cocoa flavanols — the major ingredient in dark chocolate — multivitamins, and health impacts, including effects related to cognition. In 2023 and 2024 it linked the humble daily multivitamin to benefits for cognitive aging and a reduction in cognitive decline, with consistent findings in three separate placebo-controlled studies in COSMOS.
Manson, like all health researchers, is keeping a wary eye on cuts to federal research funding. (A halt to support for the Women’s Health Initiative was reversed after an outcry.) Her own funding hasn’t been affected, though proposed cuts to indirect research costs would have a significant impact, as studies like VITAL and COSMOS have major infrastructure and blood repository costs. She’s concerned about cutbacks beyond her own division’s research, because they will have broad impact on science and prevention nationally, as well as on training programs and pipelines for future generations of scientists.
“It’s distressing what’s happening,” Manson said. “We’re very concerned, obviously, about our faculty and staff supported by federal funding, but it really goes far beyond the impact on any individual division or research program. It’s really the nationwide, and even global, impact on the scientific enterprise and population health.”
Campus & Community
Harvard amends lawsuit to push back against new funding cuts
Harvard University. Stephanie Mitchell/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
May 13, 2025
4 min read
Government is seeking to ‘micromanage’ University, complaint says, posing threat to advances in health and science
Harvard amended its lawsuit against the Trump administration on Tue
Harvard amends lawsuit to push back against new funding cuts
Harvard University.
Stephanie Mitchell/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
4 min read
Government is seeking to ‘micromanage’ University, complaint says, posing threat to advances in health and science
Harvard amended its lawsuit against the Trump administration on Tuesday to account for the most recent round of cuts to research funding. The government’s actions violate federal law and the University’s First Amendment rights and have no link to charges of campus antisemitism, the complaint says.
The original complaint was filed on April 21 and asked the court to vacate and set aside the termination of $2.2 billion in grants. Last week, U.S. Education Secretary Linda McMahon informed the University that it should no longer seek federal grants “since none will be provided.” On Tuesday, the federal Joint Task Force to Combat Antisemitism said that Harvard researchers would lose another $450 million in grants from several agencies.
In the weeks since the original suit was filed, Harvard has received grant termination letters from the National Institutes of Health, the U.S. Department of Agriculture, the Department of Energy, the Defense Department, the National Science Foundation, and the Department of Housing and Urban Development. The letters echo one another, saying that awards have been terminated because the projects “no longer effectuate agency priorities,” and that there is, in essence, no way to modify the projects so they would become acceptable.
At risk, the amended complaint contends, is the University’s ability to continue research that has contributed to breakthroughs in health, science, national security, and other fields.
“All told, the tradeoff put to Harvard and other universities is clear. Allow the government to micromanage your academic institution or jeopardize the institution’s ability to pursue medical breakthroughs, scientific discoveries, and innovative solutions,” the complaint says.
Harvard President Alan Garber, in a letter sent to McMahon on Monday, sought to seek common ground with some Trump administration priorities, highlighting University initiatives to fight antisemitism and its efforts to encourage constructive disagreement on campus, among other actions.
“As your letter suggests, we share common ground on a number of critical issues, including the importance of ending antisemitism and other bigotry on campus,” Garber wrote. “Like you, I believe that Harvard must foster an academic environment that encourages freedom of thought and expression, and that we should embrace a multiplicity of viewpoints rather than focusing our attention on narrow orthodoxies.”
But he rejected as unlawful Trump administration demands that include governance and hiring changes and “audits” of student and faculty viewpoints, pushing back against “the federal government’s overreach into the constitutional freedoms of private universities and its continuing disregard of Harvard’s compliance with the law.” The administration, he said, has “ignored the many meaningful steps we have taken and will continue to take to live up to our principles and improve the lives of people across the country and throughout the world.”
The lawsuit argues that the government is seeking to coerce ideological balance and therefore violating the University’s right to free speech. The funding freezes and terminations announced so far also ignore procedures laid out in federal law through which complaints about civil rights violations are investigated and resolved, the University says.
Garber has repeatedly highlighted several University reforms aimed at combating antisemitism. Last month, he accepted the reports of two task forces investigating antisemitism and anti-Muslim and anti-Palestinian bias, describing them before their release as “hard-hitting and painful.”
In his letter to McMahon, Garber said additional steps taken by Harvard in recent months include new investments in the study of Judaism and related fields and new initiatives to make Harvard more pluralistic and welcoming from the standpoint of intellectual diversity. He also disputed claims that Harvard is a partisan institution.
“It is neither Republican nor Democratic,” Garber wrote. “It is not an arm of any other political party or movement. Nor will it ever be.”
Campus & Community
David Deming named Harvard College dean
Stephanie Mitchell/Harvard Staff Photographer
May 13, 2025
5 min read
Economist who serves as Kirkland House faculty leader begins in new role July 1
David Deming — Isabelle and Scott Black Professor of Political Economy at Harvard Kennedy School, professor of education and economics at the Harvard Graduate School of Education, and faculty
Economist who serves as Kirkland House faculty leader begins in new role July 1
David Deming — Isabelle and Scott Black Professor of Political Economy at Harvard Kennedy School, professor of education and economics at the Harvard Graduate School of Education, and faculty dean of Kirkland House — was named Danoff Dean of Harvard College on Tuesday. He begins in his new role July 1.
In announcing the appointment, Edgerley Family Dean of the Faculty of Arts and Sciences Hopi Hoekstra said: “A recognized and respected expert in higher education research and policy, an inspiring academic leader, and a beloved faculty dean with a deep, authentic connection to undergraduate life, David is uniquely well-suited to lead the College at this consequential moment in Harvard’s history.”
“David is a stellar researcher, a great educator, a beloved faculty dean, and a role model to students and faculty alike,” said Harvard President Alan M. Garber. “His work on education and social mobility, and much else, gets to core questions in education, and I have benefited greatly from his expertise and his ability to distill the key implications of his research. I am excited that he has agreed to take on this critical role for the College and the University, as he shapes the experiences of generations of undergraduates.”
Deming is a nationally recognized scholar at the intersection of education, labor markets, and economic inequality. He is a principal investigator with the CLIMB Initiative at Opportunity Insights, which studies how higher education drives social mobility and how policymakers and institutions can amplify that impact. He also co-leads the Project on Workforce, a cross-Harvard initiative that focuses on preparing students for meaningful careers in a rapidly changing labor market. In addition, Deming co-founded the Skills Lab, which creates performance-based measures of “soft” skills, such as teamwork and decision-making. His most recent work explores how the rapid adoption of generative artificial intelligence has affected jobs and the economy.
Deming’s “work explores how education transforms lives, especially for low-income and first-generation students, and how public policy can expand opportunity and upward mobility,” said Hoekstra in a message to the FAS community. “His research blends rigorous economic analysis with a strong sense of purpose: to ensure that education systems work better for more people.”
“David embodies the many virtues and traits needed in a great Harvard College Dean,” said Claudia Goldin, Henry Lee professor of Economics, who co-authored research with Deming when he was a graduate student and is a long-time colleague. “He is a caring and committed colleague; an empathetic friend, teacher, and father; and a gifted communicator.
“David has been a leader in labor market research on the roles of social skills and teamwork. His most recent work reveals how generative AI is impacting education and employment and explores the similarities of this technological disruption to those of the past. David exemplifies veritas as a person and as a researcher.”
Deming began teaching in Harvard College in 2018. He and his wife, Janine Santimauro, became faculty deans of Kirkland House in 2020. During their five years of leadership, Deming and Santimauro have transformed the Kirkland community, fostering connection and camaraderie through intramural sports; “Kirkland Teaches Kirkland,” where students share their senior theses with the House community; and new student-initiated traditions like “The Choosening,” a Sunday night ceremony to announce and celebrate a House-wide theme for the week.
“As a faculty dean, I’ve loved getting to know our students outside the classroom and contributing to their academic and personal development,” said Deming. “While our current moment brings many challenges, I believe deeply in the intellectual rigor and transformative power of a Harvard College education and experience. I am honored to become the next dean and excited to work with Dean Hoekstra and Harvard leadership as we chart a path forward.”
Deming has held multiple leadership roles during his time at Harvard, serving as director of the Malcolm Wiener Center for Social Policy at the Kennedy School and later becoming the School’s academic dean, a position he held until 2024.
Born in Nashville, Deming moved to Shaker Heights, Ohio, when he was 15. He holds degrees in economics and political science from Ohio State University, a master’s degree from the Goldman School of Public Policy at the University of California, Berkeley, and a Ph.D. from the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences in the HKS policy program. After beginning his career at Carnegie Mellon, he joined Harvard as an assistant professor at HGSE in 2011 and was promoted to full professor with tenure in 2016.
In 2022, Deming won the Sherwin Rosen Prize for outstanding contributions to labor economics. In 2018, he was awarded the David N. Kershaw Prize for distinguished contributions to the field of public policy and management under the age of 40. He has written columns for The New York Times and The Atlantic and is a research associate at the National Bureau of Economic Research.
Deming succeeds Rakesh Khurana, Marvin Bower Professor of Leadership Development at Harvard Business School and a professor of sociology in the FAS, who is stepping down as dean at the end of the academic year, following 11 years of service to Harvard College.
Harvard file photo
Campus & Community
Walter Jacob Kaiser, 84
Memorial Minute — Faculty of Arts and Sciences
May 13, 2025
6 min read
At a meeting of the Faculty of Arts and Sciences on May 6, 2025, the following tribute to the life and service of the late Walter Jacob Kaiser was spread upon the permanent records of the Faculty.
Walter Jacob Kaiser, Francis Lee Higginson Professor of English Litera
At a meeting of the Faculty of Arts and Sciences on May 6, 2025, the following tribute to the life and service of the late Walter Jacob Kaiser was spread upon the permanent records of the Faculty.
Walter Jacob Kaiser, Francis Lee Higginson Professor of English Literature and Professor of Comparative Literature, Emeritus, led a life of vibrant culture, knowledge, and accomplishment.
In 1963 Kaiser published “Praisers of Folly: Erasmus, Rabelais, Shakespeare,” a study of Renaissance humanism, philosophy, witty fools, and cosmopolitanism based on his dissertation. The next year saw his edition of the essays of Michel de Montaigne in John Florio’s English. Kaiser soon produced translations, first of three longer poems from the modern Greek by the Nobel laureate George Seferis 1969 and later of three volumes of prose from the French by Marguerite Yourcenar, the first woman elected to the Académie Française: “Alexis” (“Alexis ou le traité du vain combat”) in 1984; “Two Lives and a Dream” (“Comme l’eau qui coule”) in 1987; and, in 1992, “That Mighty Sculptor, Time,” a collection of Yourcenar’s essays on which he collaborated. His skill as a translator drew praise, including from the reviewer Philip Thody in the Times Literary Supplement in 1992. Kaiser’s 1983 essay, “The Achievement of Marguerite Yourcenar,” is an important contribution to English criticism of that writer.
Kaiser devoted much of his career at Harvard to revitalizing Villa I Tatti, the University’s Center for Italian Renaissance Studies in Florence, Italy, housed in Bernard Berenson’s villa and grounds in the valley of the Mensola in the hills northeast of the city. The choice of Kaiser to lead this institution had a certain logic. As an undergraduate in 1953, he had met Berenson — “I was terrified,” he later recounted — but the two became acquainted on walks. Thirty-five years later, Walter became I Tatti’s director. During his tenure, serving from 1988 to 2002, he consolidated its scholarly programs and gave new life and vitality to its garden, properties, people, and programs.
According to one member of the Memorial Minute Committee, a visiting professor at I Tatti in 1991, when Kaiser was director, “he was absolutely perfect for the position. Presiding at daily lunches with grace and humor, he always managed to steer the conversation to the varied and interesting research projects of the Fellows. . . . Walter loved the gardens and saw to it that they were kept in the best possible condition of each season. His Italian and French were perfect. He could talk about anything with anyone. He was loved and admired by staff and fellows. He presided like a happy Renaissance Prince of the Church, lavishing his blessings on his guests. He knew how to raise money and keep order so that a very complicated organization seemed to flow effortlessly. Walter was smart, sharp; he loved to laugh and make people laugh with him!”
The present director, Alina Payne, remarks how much she benefited from Kaiser, “both as a scholar and personally from what he managed to build . . . at I Tatti — the community, the place, the grounds, and its sound financial basis.” He oversaw the expansion of the library and photo collection. His efforts were marked by the establishment of a fund named in his honor to support the Biblioteca Berenson at Villa I Tatti and, in 2018, by the reopening of its newly renovated main space as the Walter J. Kaiser Reading Room.
Kaiser also inaugurated a library of a different sort: the I Tatti Renaissance Library. This highly regarded series of Latin literary, historical, philosophical, and scientific texts with facing English translations, distributed by Harvard University Press, now runs to more than one hundred volumes. He also contributed to the Press’s Villa I Tatti Series, which publishes studies on topics related to Bernard Berenson, his colleagues, interests, and collections, editing, with Michael Mallon, a selection of book reviews by the eminent art historian John Pope-Hennessy.
Above all, Kaiser valued interdisciplinarity. Under his direction, I Tatti focused on the Italian Renaissance, a purview since expanded to encompass the broader Mediterranean. For more than seven decades, I Tatti has supported scholarly work in many fields, including literature, history, art history, philosophy, and musicology. Kaiser called the resulting conversation among the disciplines “the greatness of I Tatti.”
Before his directorship of I Tatti, Kaiser taught courses featuring Shakespeare, Spenser, Ariosto, and Montaigne. He enlivened his lectures on Shakespeare with analysis, criticism, and a marvelous ability to play characters in different voices. Memory of his renderings of Falstaff, Justice Shallow, and Justice Silent in “Henry IV, Part 2,” never fades. When one student asked what, aside from verbal ability, permitted Shakespeare to become a great poet, Kaiser replied, “He was open to every kind of experience.”
From 2009 through 2015, Kaiser wrote essays and reviews for The New York Review of Books. His subjects reflected his wide interests: Renaissance and American art, connoisseurship, the task of translation, Paul and Julia Child in the Office of Strategic Services, Arezzo, Florence, Shakespeare, modern European painting, Caravaggio, Piero della Francesca, Janet Ross, and Bernard Berenson. In these essays, as in all his undertakings, he connected learning to living as much as to the academy.
Born May 31, 1931, in Bellevue, Ohio, the son of a grocer, Kaiser earned the position of page in the U.S. Senate in 1944, followed by scholarships to Phillips Academy and Harvard, which conferred his A.B. magna cum laude with highest honors in 1954 and his Ph.D. in 1960. He published poems in The Harvard Advocate and The New Yorker. Appointed assistant professor of English and comparative literature in 1962, promoted to associate professor in 1965, and tenured in 1969, he was, in 1999, granted a named professorship. From the late 1960s through the mid-1980s, he chaired the Department of Comparative Literature three times, totaling eight years.
Before divorcing in 1981, Kaiser and Neva Goodwin Rockefeller had two children. Kaiser is survived by his daughter, Miranda Kaiser; her two daughters; and two daughters by his son, David Kaiser, a courageous climate advocate who died in 2020. Walter Kaiser died peacefully in New York City on Jan. 5, 2016.
Respectfully submitted, Robert Kiely Katharine Park Jan Ziolkowski James Engell, Chair
Gloria Ferrari Pinney.Photo by Laura Slatkin
Campus & Community
Gloria Ferrari Pinney, 82
Memorial Minute — Faculty of Arts and Sciences
May 13, 2025
6 min read
At a meeting of the Faculty of Arts and Sciences on May 6, 2025, the following tribute to the life and service of the late Gloria Ferrari Pinney was spread upon the permanent records of the Faculty.
Some friends had occasion a few years a
At a meeting of the Faculty of Arts and Sciences on May 6, 2025, the following tribute to the life and service of the late Gloria Ferrari Pinney was spread upon the permanent records of the Faculty.
Some friends had occasion a few years ago to ask a distinguished classical archaeologist her opinion of the scholarship of an art historian in her own field of Greek vase painting — her view was highly positive, so one friend said, musingly, “I wonder if that person’s work is as original as Gloria Ferrari Pinney’s?” The archaeologist’s immediate response was, “That would be impossible!”
Gloria Ferrari Pinney’s internationally renowned scholarship, which transformed the study of her field, was brilliantly original — and she was an original: resolutely independent-minded and, at the same time, a tireless collaborator; endlessly generous — intellectually, and in every way — to colleagues and friends old and new; inspiring to her many students and mentees across the globe, and inspiringly loyal to them; and, as seriously as she took everyone she dealt with, she never took herself too seriously. She had a hilarious sense of humor and a profound modesty that one could describe as hard-wired. On the matter of originality, Pinney may be the only Classicist one knows who took flying lessons as a teenager and became proficient at it.
Pinney was born in Bologna, Italy, in 1941 and died in Sept. 2023 in New Jersey, where she had moved to be near her daughter, Dr. Antonia Pinney, and Antonia’s family. Her father, Antonio Ferrari, was an Italian air force pilot and died in the war before she was born, and her mother, Laura, subsequently moved to Rome, where Pinney grew up and then did her undergraduate studies at the Università degli Studi di Roma, receiving a Laurea in Lettere Classiche in 1964. She stayed in Rome for two more years, studying at the Scuola Nazionale de Archeologia and the American Academy in Rome, where she was a Fulbright Scholar in 1965–66 and took part in excavations in Cosa, under the auspices of the American Academy, and at Punta della Vipera. In 1966 Pinney married a young American architect, Paul Pinney, and moved with him to his home in Kentucky, where her daughter was born several years later. She pursued doctoral work at the University of Cincinnati, where she wrote a dissertation on early red-figure vase painting and earned a Ph.D. in 1976. After beginning her teaching career that same year at Wilson College in Pennsylvania, in 1977 she moved to Bryn Mawr College, where she taught in the Department of Classical and Near Eastern Archaeology, holding the Doreen Canaday Spitzer Professorship in Classical Studies until 1993, when she joined the University of Chicago’s Departments of Art History and of Classical Languages and Literatures. She came to Harvard in 1998 as a member of the Department of the Classics and retired in 2003.
Over the years, Pinney’s illuminating, innovative scholarship was recognized by notable fellowships and distinctions, including those from the Guggenheim Foundation, the National Humanities Center, the National Endowment for the Humanities, the Stanford University Center for Advanced Study in the Behavioral Sciences, and the National Gallery of Art’s Center for Advanced Study in the Visual Arts.
The American Philosophical Society described her pathbreaking scholarship when she was elected a member in 2003: “Gloria Ferrari Pinney combines a deep knowledge of classical philology and keen artistic sensitivity with a penetrating critical acumen that allows her to reach unprecedented and often revolutionary conclusions about even well-known ancient monuments. Her pioneering study on the origin of Asiatic sarcophagi was in fact disregarded by scholars for almost 20 years until excavational finds confirmed her hypothesis. Within her great range, she is an expert in Greek vase painting, with emphasis on iconography, yet two of her recent publications — on the North metopes of the Parthenon (2000) and the architecture of the Archaic Akropolis (2002) — are among her most startling contributions. Although well versed in current art-historical and linguistic theory, she produces terse and concise analyses that carry conviction with their strict logic.”
In 2004, Pinney received the Archaeological Institute of America’s James R. Wiseman Book Award for “Figures of Speech: Men and Maidens in Ancient Greece” (2002). Its citation reads, in part, “This fruitful interaction between the visual and textual evidence makes Gloria Ferrari Pinney’s study truly interdisciplinary, and of importance to philologists as well as to archaeologists. “Figures of Speech” is provocative and thoughtful — its sophisticated approach to Greek culture and images should guide discussion in the future.”
Continuing to extend her already formidable range of research interests, after retiring Pinney published such innovative works as “Alcman and the Cosmos of Sparta” (2008), which was praised in reviews as “entirely original” and “an important contribution to the study of ancient Greek choral poetry, archaeology, and art history,” as well as major articles and book chapters on such subjects as the Nile mosaic at Praeneste; the metaphor of architectural space in the Greek sanctuary; anthropological approaches to the study of ancient Greek and Roman art; and metaphors of eros in Thucydides’ “History of the Peloponnesian War.” She was named a Phi Beta Kappa Visiting Scholar in 2011–12 and lectured at universities across the country.
Pinney’s students from around the globe — many now eminent scholars themselves — became her lifelong friends. In gratitude for her invaluable, dedicated mentorship, and to celebrate her 80th birthday, they organized a series of monthly online workshops, in which they met to present work directly inspired by Pinney’s contributions to their fields. These workshops continued for two full years — and, in true Pinney fashion, she herself attended each of them and offered incisive feedback, even as her health declined.
Any tribute to Pinney must underscore above all her unshakeable democratic, inclusive ethos; her native intellectual openness; her commitment to feminist ideals; her open-handed hospitality, her devotion as daughter, mother, and grandmother; and her steadfast attachment to Italy and beloved friends there. Gloria was always the first, as all who knew her can attest, to stand up for Harvard’s ideals in protecting freedom of thought and inquiry.
Respectfully submitted,
Emma Dench Laura Slatkin (New York University) Gregory Nagy, Chair
Emerson Hall at Harvard University. Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Charles Dacre Parsons, 91
Memorial Minute — Faculty of Arts and Sciences
May 13, 2025
5 min read
At a meeting of the Faculty of Arts and Sciences on May 6, 2025, the following tribute to the life and service of the late Charles Dacre Parsons was spread upon the permanent records of the Faculty.
Cha
At a meeting of the Faculty of Arts and Sciences on May 6, 2025, the following tribute to the life and service of the late Charles Dacre Parsons was spread upon the permanent records of the Faculty.
Charles Parsons was a philosopher of logic and mathematics of great penetration, known for clarifying difficult issues, deeply scrutinizing problems of long standing and their attempted solutions, and articulating both judicious proposals to make progress on them and acute analyses of the difficulties that still stood in the way.
Parsons was raised in Belmont, Massachusetts. His father was Talcott Parsons, the eminent Harvard sociologist, and Parsons grew up in a Harvard atmosphere. He was educated at the University, graduating from the College in 1954 summa cum laude in mathematics and entering the philosophy Ph.D. program after a year in Cambridge, England, on a Henry Fellowship. He joined the Society of Fellows in 1958 and completed his Ph.D. and the Junior Fellowship simultaneously in 1961. After three years as an assistant professor at Harvard, he moved to Columbia University, where he taught for 24 years. He returned to Harvard in 1989, becoming the Edgar Pierce Professor of Philosophy in 1991, and retired in 2005.
Parsons’s dissertation and early research work focused on mathematical logic, in which he obtained some noteworthy results in fine-grained analyses of the deductive strength of various axiom systems for areas of mathematics. Subsequently his interests turned towards less purely technical matters, and his writing concentrated on philosophy of logic and of mathematics. In the 1960s and 1970s he published highly influential papers in this area, collected in his first book, aptly titled “Mathematics in Philosophy” (1983). These papers included his careful examinations of the foundations of set theory and of the Liar Paradox, the seemingly paradoxical consequences of the sentence that says of itself that it is not true. The latter, in particular, spawned a large industry of proposed solutions based on Parsons’s work. But perhaps most striking from this part of his career was his attention to Kant. Before Parsons’s work, Kant — whose concern with mathematics is central to his entire philosophical system — had been dismissed as irrelevant to contemporary philosophy of mathematics due to the subsequent development of modern logic, non-Euclidean geometry, and the theory of relativity. Parsons, almost single-handedly, brought Kant back into dialogue with contemporary philosophy of mathematics by locating what was still of interest in his philosophical structures that might be of help in solving the conundrums that contemporary philosophy of mathematics had encountered. To do this, Parsons also made major contributions to pure Kant scholarship, particularly in his exposition of the role Kant’s notion of intuition plays in a crucial section of the “Critique of Pure Reason.”
Parsons’s resuscitation of Kant had a mode of operation in common with all of his work. He never said outright “That position isn’t going to work.” He always carefully drew out what strands in a position might be able to make contributions to current understanding while gently suggesting which other parts were more troublesome.
Parsons’s work in philosophy of mathematics and logic inspired by historical figures was ongoing. Two more collections of his published essays eventually appeared, titled “From Kant to Husserl” (2012), with essays on Kant, Frege, Brentano, and Husserl, and “Philosophy of Mathematics in the 20th Century” (2014), which continued his conversation linking Kant to contemporary philosophy of mathematics but also considered later figures, particularly the pathbreaking logician Kurt Gödel and the Harvard philosopher W. V. Quine, who was one of Parsons’s teachers.
Parsons’s greatest contribution to modern philosophy of mathematics is his final statement of his mature considered views, “Mathematical Thought and Its Objects” (2008). The first half of this volume took off from his seminal paper “Objects and Logic” (1982), which closely examined what it could amount to be a mathematical object. The ultimate result was a sober defense of a view in philosophy of mathematics known as “structuralism,” which argues that there should be no question of what a mathematical entity is but only of what structure it plays a role in. Other contemporaries have defended a view in this neighborhood, but they usually turn out to be implicitly assuming some notion of mathematical entity. Parsons’s work was exemplary in avoiding any such hidden presuppositions, so that his defense of structuralism was the tightest and most convincing. The second half of the book examined epistemological issues, focusing on the role of reason and the room for some notion of Kantian-style intuition in the concept of evidence for a wide range of mathematical theories. Throughout the book, Parsons drew on all his historical work in formulating and appraising various proposed solutions.
Parsons was a devoted graduate teacher. Despite his initial somewhat austere demeanor, his dissertation students at both Columbia and Harvard quickly came to appreciate his kindness and benevolent scholarly attention and became loyal friends. Many of Parsons’s students became major figures in philosophy of mathematics, Kant scholarship, Husserl scholarship, and philosophy of logic and language. Parsons was also well known for a quirk, in both lecturing and informal personal conversation, of pausing in mid-sentence, clearly reflecting on whether what he was about to say was really accurate and, even after a full minute (or even two) of silence, picking up that sentence at the point he had left it.
Parsons was predeceased in 2017 by his wife of 49 years, Marjorie (née Wood). He is survived by their son, Dr. Jotham Parsons (Harvard College Class of 1990); their daughter, Dr. Sylvia Parsons (Harvard College Class of 1992); and two grandchildren.
Respectfully submitted,
Peter Koellner Christine Korsgaard Thomas M. Scanlon Warren Goldfarb, Chair
Campus & Community
New Learning Experience Platform opens doors to innovation in teaching
The LXP’s rollout celebration was held at Harvard Business School’s Batten Hall with more than 120 in attendance.
Jessica McCann
Harvard Correspondent
May 13, 2025
5 min read
Flexible, modular platform supports unique pedagogical approaches
Harvard marked a milestone in January with the launch o
Harvard marked a milestone in January with the launch of the Learning Experience Platform (LXP) — a University-wide initiative designed to support innovative teaching and enable cutting-edge digital learning experiences.
Hosted at Harvard Business School’s Batten Hall, more than 120 participants, including faculty, deans, and senior administrators, gathered to celebrate the LXP’s rollout. In his opening remarks, Vice Provost for Advances in Learning Bharat Anand underscored the collaborative nature of the effort, developed jointly by the Office of the Vice Provost for Advances in Learning (VPAL), Harvard University Information Technology (HUIT), and Harvard Business School.
“This is about ensuring we retain control over our pedagogical future,” Anand said. “We’ve built a platform that reflects Harvard’s values — one that’s modular, flexible, and rooted in over a decade of innovation in online learning.”
Ten years in the making
Harvard has long been a leader in digital learning. From co-founding edX in 2012 to pioneering asynchronous case-based learning through HBS Online, the University has consistently explored how technology can expand access and enhance learning.
The pandemic accelerated this shift, highlighting both the opportunities and limitations of existing platforms. The 2022 Harvard Future of Teaching and Learning Report identified, among other things, the need for a modern digital learning platform to match the excellence of Harvard’s physical infrastructure.
LXP answers this call. Built to support online and hybrid learning, it offers a flexible, modular platform that supports a wide range of teaching styles and course lengths and leverages innovative “teaching elements” around peer and active learning, including “online cold calls” and tools for surfacing viewpoint diversity. It enables consistent, high-quality learning experiences for everyone from first-years to alumni and global learners.
Solving for fragmentation
One of the motivations for building the LXP was to reduce the complexity and fragmentation of the digital learning ecosystem. “If a learner wanted to find a Harvard course on AI or climate change today, they’d have to visit over a dozen websites,” Dustin Tingley, deputy VPAL, noted.
“There are 40-plus learning platforms that are currently managed by HUIT, creating technology clutter and cost inefficiencies,” said Emily Bottis, HUIT’s managing director for academic technology.
“We needed to solve that fragmentation and inefficiency while preserving the ability to innovate locally,” added Zachary Wang, VPAL’s director of strategic technology.
The LXP consolidates efforts across Schools and allows for consistency in experience while supporting unique pedagogical approaches. Seven Harvard Schools already use the platform in different ways.
Early successes
The first program launched on the platform was a pre-matriculation course for incoming Harvard Law School students — 20 hours of foundational content that other law schools now can customize for their own needs. This kind of modularity, said HLS Online Executive Director Leah Plunkett, is one of LXP’s greatest strengths: “You can create once and customize infinitely.”
Another milestone came last summer, when more than 1,600 incoming Harvard College first-years completed three short orientation modules through the LXP. These included videos featuring faculty, polls, peer-engagement tools, and interactive content.
“I think what really was the innovation last summer [in online orientation] was getting students excited,” said Katherine Veach, assistant dean for first-year academic programs. “We were able to deliver essential information in a way that felt personal and engaging. Students heard directly from faculty they may have already known, read, or were eager to learn from. The platform made that experience memorable and interactive at scale in a way emails never could.”
Designed for what’s next
LXP is already supporting a broad range of learning experiences, from short modules to semester-long programs, with plans underway to expand offerings for Harvard’s alumni and international partners. Its flexibility enables everything from 15-minute tutorials to multiweek blended courses.
“A 12-week semester is natural for residential learning,” said Anand. “But online, that format doesn’t always make sense. What if an executive program met one day a week for five weeks? Or what if a course could adapt its length to fit the learning outcomes, rather than the academic calendar, whether that meant 10 weeks or 10 hours? The LXP allows Harvard to design around the needs of the learner — not the limitations of legacy systems.”
Built on three big ideas
Anand described three principles that guided the LXP’s creation.
First, pedagogical creativity: “Our faculty are full of ideas for innovative teaching. They shouldn’t have to fit those ideas into one-size-fits-all platforms. The LXP gives them the flexibility to design learning experiences that truly reflect their vision.”
Second, a One Harvard vision: “The platform is available to all Harvard’s Schools and ensures a consistently high-quality learning experience across each, while still allowing for local customization to reflect each School’s unique voice, priorities, and pedagogy.”
Third, global reach: “Whether through online courses, livestreams, or blended experiences, the LXP allows one to deliver on the University’s mission to engage learners at scale far beyond campus.”
With the platform now live, faculty are encouraged to explore new ways to elevate their teaching and connect with learners.
“We’ve built the foundation,” Anand said. “It’s now up to our faculty and academic staff to imagine what comes next, and to create learning experiences that are as inspiring and impactful as the ideas we teach.”
Jodie Foster (right) talks with Henry Louis Gates Jr. Photos by Veasey Conway/Harvard Staff Photographer
Campus & Community
When Jodie Foster found out acting wasn’t a dumb job
Christina Pazzanese
Harvard Staff Writer
May 12, 2025
5 min read
Celebrated performer, filmmaker — and now Radcliffe Medalist — discusses sometimes thorny complexities of six-decade career
Jodie Foster always
When Jodie Foster found out acting wasn’t a dumb job
Christina Pazzanese
Harvard Staff Writer
5 min read
Celebrated performer, filmmaker — and now Radcliffe Medalist — discusses sometimes thorny complexities of six-decade career
Jodie Foster always thought she’d become a writer.
“I didn’t really think I wanted to be an actor when I grew up because it seemed like kind of a dumb job,” the Academy Award-winning actor and filmmaker said during a Radcliffe Day event Friday with Henry Louis Gates Jr., Alphonse Fletcher University Professor and director of the Hutchins Center for African and African American Research.
Acting seemed too superficial to be intellectually satisfying as a career, she said. But then, Robert De Niro took her under his wing and worked with her on improvisation skills while the two starred in “Taxi Driver.” DeNiro was the lead in the 1976 Oscar winner, and Foster played a young sex worker, a role for which she received her first Academy Award nomination.
“My 12-year-old mind was blown. I suddenly understood that acting was more than just saying lines and ‘being yourself,’” she told Gates, who was Foster’s thesis adviser at Yale in the early 1980s. “I hadn’t looked at it the way I might look at a book or the way I might look at a painting. I hadn’t really looked at it as an art form, and … It was up to me to challenge myself to go beyond that.”
Foster was on hand at the Harvard Radcliffe Institute to receive the 2025 Radcliffe Medal, presented by Dean Tomiko Brown-Nagin, for her accomplishments over a six-decade career as an actor and filmmaker, and her advocacy for suicide prevention among LGBT youth.
Jodie Foster (right) stands with Tomiko Brown-Nagin.
As part of the annual Radcliffe Day celebration, Foster spoke about her evolution from 1970s Disney child star to celebrated filmmaker and two-time Academy Award winner for leading roles in “The Accused” (1988) and “Silence of the Lambs” (1991).
Famously private, Foster delved into the trauma she experienced as an 18-year-old Yale freshman after a stalker shot President Ronald Reagan in 1981 in a bid to win her favor. She was forced into hiding, couldn’t live on campus or attend classes anymore, and needed round-the-clock security.
The ordeal was, she said, “a trial by fire. I became adult really quickly” and learned some good life lessons about the value of community and also some bad ones, like “now you can trust no one.”
Foster said she deliberately avoided talking about the experience for decades.
“I wanted to have a long career where I was known for myself and for my work, and I wanted my identity to be about what I produced,” she explained to Gates. “I just didn’t want to be ‘that girl’ who was chosen abstractly by an insane man to be a footnote in history.”
“I wanted to have a long career where I was known for myself and for my work, and I wanted my identity to be about what I produced.”
Foster also talked about being a mother and of the complicated relationship she had with her own. Brandy Foster, a single mother of four, pushed her daughter into acting and modeling at age 3 and managed her career for many years, steering her toward many films that achieved critical and commercial success.
“Because of her generation and her status [as a] pre-feminist woman, she wanted me to be respected above anything else, and so she engineered, in some ways propelled me in, a career where she could feel respected because her daughter was respected,” she said. “That was a big burden and a big responsibility.”
Diana Nyad, the record-breaking endurance swimmer who inspired “Nyad,” the 2023 biopic for which Foster earned her fifth Oscar nomination, spoke about Foster’s meticulousness as an actor and her status as a somewhat reluctant lesbian icon.
Academy Award–nominated director Mira Nair ’79 (second from left) speaks during a panel discussion.
Diana Nyad.
Foster said she feels proud that people say she helped facilitate greater acceptance of LGBTQ people in the film industry, but she wishes she “could have done more” to be an outspoken leader.
“My No. 1 concern … was surviving intact, emotionally and intellectually,” she said. “What I didn’t want to do was end up dead in a hotel room with a needle in my arm.” Accomplishing that required “a kind of emotional safety and privacy that was unusual for the film business” then and perhaps more so now.
“I don’t think I would have survived it intact” if she’d been a young actor now, Foster said. “But in those days, the way to survive that was to say, ‘I am off limits. You can’t have me. You can have all this part that I give you. You can have my art… You can count on me, but you can’t have all of me.”
Earlier in the day, actor Amy Brenneman ’86, acclaimed filmmaker Mira Nair ’79, Naomi McDougall Jones, an advocate for gender parity in film industry, and television showrunner Saladin K. Patterson spoke with Stacy L. Smith, a professor of communication at the University of Southern California’s Annenberg School of Communication and Journalism, about how underrepresented women remain in the film and television industry the obstacles that still need to be overcome both in front of and behind the camera, despite societal gains.
Since 1987, the Harvard Radcliffe Institute each year has recognized outstanding women who have made a lasting impact on the world. Past recipients include Supreme Court Justices Sonia Sotomayor and Ruth Bader Ginsburg, labor activist Dolores Huerta, former Secretary of State and New York Senator Hillary Clinton, and Nobel Prize winning author Toni Morrison.
Campus & Community
Finishing what he started
Veasey Conway/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
May 12, 2025
7 min read
Ben Abercrombie battles back to graduate 8 years after spinal-cord injury on football field left him paralyzed
Part of the
Commencement 2025
series
A collection of features and profiles covering H
A collection of features and profiles covering Harvard University’s 374th Commencement.
Outwardly, everything has changed since he broke his neck in his first Harvard football game in 2017. But Ben Abercrombie says he’s not all that different on the inside.
He still loves football. He still considers himself determined and hard-working — a point with which those around him emphatically agree. He still plans to go into personal finance when he graduates from Harvard College this spring, a career that, if all goes well, will have him guiding professional athletes’ personal wealth, blending his interests in economics and sports.
He admits, though, that it’s hard having to ask for help all the time.
“That’s one thing. I used to try to do everything myself,” Abercrombie said. “I like to think I haven’t changed too much, but it does open your eyes not to take things for granted, to be thankful for what you have, for your family, and for the grace that people show you.”
That grace helped Abercrombie navigate a tough eight years. That determination got him back to Harvard after two years of rehabilitation, of learning how to live paralyzed below the neck, and how to get around in a wheelchair and guide a laptop computer with his eyes. That hard work has him graduating with a degree in economics after years of coursework that competed with his new reality, where even getting out of bed takes longer. And all of that has made him an inspiration to those around him, even those whose role once was to inspire him.
“As a coach, part of my job is to motivate, but every time I would see Ben after his accident — with very few exceptions — he was in such high spirits, laughing, talking football, that he motivated me,” said former Crimson football coach Tim Murphy, who recruited Abercrombie to Harvard and was standing just feet away from the seemingly routine tackle that changed Abercrombie’s life. “He makes my day. They are a remarkable family on many levels.”
Abercrombie works on a laptop computer in his dorm room with the aid of assistive technology.
Even before the injury, Abercrombie was a standout, said Murphy, who retired as the Ivy League’s winningest coach in 2024. Abercrombie was recruited from Hoover, a suburb of Birmingham in football-mad Alabama, to play safety for Harvard. He was the only freshman defensive player to suit up with the team in fall 2017 for the season opener at the University of Rhode Island. And, when a starter injured a hamstring during the opening kickoff, Abercrombie got the nod, covering the deep right side of the field.
Just before halftime, Abercrombie recognized the receiver’s route and broke toward him as the ball was thrown. Murphy, standing nearby, saw the tackle and later said Abercrombie used good technique. Still, Murphy knew something was amiss by the way Abercrombie fell to the turf.
The impact damaged two vertebrae in Abercrombie’s neck along with the nerve to the diaphragm, which controls breathing. Abercrombie was conscious long enough to realize something was wrong before passing out.
“I didn’t go home with the team, I jumped in the car with my wife, Martha, and we drove directly to the hospital,” Murphy said. “We were there for the next seven or eight hours, until about midnight. I had the opportunity to squeeze Ben’s hand just before he went into surgery. I had the opportunity to see him as he came out of surgery. I remember it like it was yesterday.”
Weeks in Providence Hospital were followed by months at the Shepherd Center in Atlanta, which specializes in brain and spinal-cord injury. There, he and his parents, Sherri and Marty Abercrombie, came to grips with how much had changed.
They returned home to Hoover in January — right before the 2018 college football title game, Abercrombie recalled. Over the next 18 months, he and his parents relearned how to live, creating new daily routines and working with the state Department of Rehabilitation Services so Abercrombie could learn to control a computer with his eyes. Sherri Abercrombie, a registered nurse, left her job to become her son’s full-time caregiver. Marty Abercrombie, a restaurant owner and manager, retired and sold the business.
Abercrombie attends an economics lecture.
A motorized wheelchair helps him navigate campus.
In 2019, Abercrombie enrolled in a summer school course through the Harvard Extension School. That fall, he returned to campus, settling into a modified suite in Winthrop House with his parents, who have been at his side since. They’ve helped with daily activities, gotten Abercrombie to and from class, and worked closely with health aides who’ve assisted with care.
“They’ve done a very nice job helping us do what we need to do,” Sherri Abercrombie said. “I’m glad he was able to come up here and is able to finish, though I do miss the weather at home, except in the summer.”
Abercrombie said he’s has been struck by the generosity of the Harvard community. The University supported his desire to return to campus, resume his studies, and graduate. El Jefe’s Taqueria in Harvard Square has held annual fundraisers, donating the proceeds to a fund created by the Harvard Varsity Club to defray the costs of his care. Former Crimson teammates also hold an annual bowling fundraiser for the fund.
Abercrombie said classes have been challenging, but he has become more adept at completing coursework. He continued to take summer classes and, a couple of years ago, was able to increase his workload from two classes per semester to three. He has kept in touch with friends and teammates via social media and has also stayed in touch with Crimson football coaches. He stops by their offices to talk football weekly while visiting the athletic complex for physical therapy. The Abercrombie family and Murphy, who retired in 2024, became close, regularly celebrating Thanksgiving at Murphy’s home on Cape Cod.
“It’s been an extraordinarily challenging path that he has undertaken since that injury and it’s taken him a long time to get his degree, but at no time was there any indication from his mom or dad or Ben that they were not going to complete their Harvard experience,” Murphy said. “I’m really excited to see him graduate in Harvard Yard. I will be there with him and his family and we’re going to have a great day.”
“As a coach, part of my job is to motivate, but every time I would see Ben after his accident — with very few exceptions — he was in such high spirits, laughing, talking football, that he motivated me.”
Tim Murphy
Abercrombie keeps an eye on advances in medical science in hopes that he’ll one day be able to breathe and move on his own. His physical therapy utilizes cutting-edge equipment such as a Locomat, a robot-assisted device that supports him and helps him move, and electric stimulation to move his arms and legs, maintaining flexibility and preventing atrophy. Using the Locomat, he’s able to walk on the treadmill for 45 minutes during his weekly two-hour session.
Progress has been slow, but Abercrombie can move his fingers slightly and feel pressure on his skin. When he sits in one position too long, his body feels uncomfortable. He recognizes the improvements are small, but they give him something to build upon. He also uses electric stimulation in an effort to build up breathing muscles in anticipation of achieving a key goal: getting off the ventilator.
Abercrombie isn’t quite sure what to expect on Commencement Day but he enjoys history, so he’s looking forward to taking part in Harvard’s centuries-old traditions. He admits that after so many years as a student he’s ready to move onto the next phase of life. This summer, he will work on passing state licensing tests and in September, plans to start work at a Birmingham-area personal finance firm.
“I’ve been in school for a decade, so I’m excited to finally be done. It’s surreal that it’s coming to a close,” Abercrombie said. “It’s been a long road for sure.”
The Arts Fest tent took center stage in Science Center Plaza.Photo by Dylan Goodman
Arts & Culture
Science Center Plaza is alive with the sound of music
Eileen O’Grady
Harvard Staff Writer
May 12, 2025
6 min read
Harvard Arts Fest brings artmaking and creativity to campus
The steady pulse of music filled the Science Center Plaza on May 3 as a crowd of students from visiting artist St
Science Center Plaza is alive with the sound of music
Eileen O’Grady
Harvard Staff Writer
6 min read
Harvard Arts Fest brings artmaking and creativity to campus
The steady pulse of music filled the Science Center Plaza on May 3 as a crowd of students from visiting artist Steven “Rhythm” Garcia’s Office for the Arts Dance Programcourse “House” moved freely to the beat, spun by DJ Luna del Flor. Suddenly, the music cut — and members of The Kuumba Singers and the Harvard Choruses began to sing “This Little Light of Mine.” A deep, resonant bass-baritone voice broke through the harmony, as opera singer Davóne Tines ’09, the recipient of the 2025 Harvard Arts Medal, rose to sing a stirring solo.
As Tines’ final note faded, Abe Joyner-Meyers ’22, American Repertory Theater sound engineer, picked up the melody on banjo. He was quickly joined by the Arts Fest Jazz Band, which launched into “When the Saints Go Marching In,” leading a parade of onlookers into the nearby tent and officially kicking off the Harvard Arts Festival’s Performance Fair.
The annual spring celebration of the arts took over stages, museums, and other venues across Harvard’s campus. The annual festival, produced by the Office for the Arts at Harvard, had nearly 2,000 participants, including students, faculty, staff, and alumni, in 150 events ranging from public concerts to theatrical performances, and hands-on art-making activities.
“This is really the culmination of art-making that’s been happening across our campus over the past year,” Fiona Coffey, director of the OFA, told the audience in the plaza tent. “This is a time when we need joy, resilience, community, collectivity more than ever. … I think that the arts are a really great example of how we can lift each other up and how we can lift up humanity during challenging times.”
Adam Bartholomew ’26, a molecular and cellular biology concentrator, and Elizabeth Bennett ’26, a music concentrator with a secondary in government, led the Harvard College Steelpan Ensemble through a resonant rendition of “Can’t Take My Eyes Off You,” made famous by Frankie Valli and the Four Seasons, to enthusiastic applause from the audience.
Operatic bass-baritone Davóne Tines ’09 (right) performs in Lowell Lecture Hall after receiving the 2025 Harvard Arts Medal, which was presented by Harvard President Alan Garber.
Photo by Grace DuVal
Bartholomew, a member of the Harvard-Berklee Joint Studies program who grew up playing steelpan in Trinidad and Tobago, said bringing the instrument to a Harvard stage has long been a dream.
“As we planned to create this ensemble over the past two years, we’ve always envisioned playing at Arts Fest once we got it started,” Bartholomew said. “The fact that it’s finally coming to fruition is a really good feeling.”
In Holden Chapel, Ethan Chaves ’26, a music and philosophy joint concentrator, performed original compositions for solo viola that were inspired by the idea of the Jungian shadow. It was a busy day for Chaves, who also performed with the Brattle Street Chamber Players in Adolphus Busch Hall earlier in the day, and had an original choral composition, “Exultation is the going,” premiered by the Harvard-Radcliffe Collegium Musicum at Memorial Church later that afternoon. Chaves, who is enrolled in the Harvard-New England Conservatory Dual Degree program, said the festival allows students to experiment with new projects.
“It’s fun because it’s so hectic, there are always about 80 things going on all at the same time,” Chaves said, “It’s nice to be able to see your friends perform different things than they usually would and try out different works in progress you don’t normally get to see.”
President Alan Garber awarded Tines the Harvard Arts Medal in a ceremony May 4 in Lowell Lecture Hall. In his remarks, Garber recalled standing beside the award-winning opera singer as he transfixed the crowd in Tercentenary Theatre with his rendition of “Lift Ev’ry Voice” at Harvard’s 2019 Commencement ceremony.
“Art conveys truth in ways that are layered and unique,” Garber said. “It enlarges our hearts as well as our minds. It compels us to deepen our understanding and to expand our perspective at its best. It challenges us to appreciate the world and one another in new ways, creating the possibility for sympathy and empathy, for real and lasting connection.”
Tines (right) smiles during a conversation with Diane Paulus, the Terrie and Bradley Bloom Artistic Director at American Repertory Theater.
Photo by Grace DuVal
The Harvard College Opera performs during the ceremony honoring Tines.
Photo by Grace DuVal
At the medal ceremony, Tines and his band The Truth performed “Let It Shine,” a stunning “This Little Light of Mine” reprise that brought the audience to its feet. He also spoke with Diane Paulus, the Terrie and Bradley Bloom Artistic Director of the A.R.T., about his time at Harvard, where he concentrated in sociology, was a member of the Harvard-Radcliffe Orchestra and sang his first opera, Stravinsky’s “Rake’s Progress,” with the Dunster House Opera Society.
Tines said his years spent working in arts administration (including as an A.R.T. intern) before becoming a performing artist helped him gain a better understanding of all the work that goes into every artistic production. He said being an artist now not only means “holding a mirror up to the world,” but also serving as a model to inspire creativity and bravery in others.
“In my ongoing quest to understand all the parts of myself and put them together in a cohesive way, I’m trying to model that that’s possible for everyone else, artists, people at large,” Tines said. “We’re made of so many things, we come from so many things, and it’s important that we honor all those things and empower ourselves to become them, even when they contradict.”
Anugraha Raman ’12 (left) and Kohal Das warm up for their performance on Science Center Plaza.
Photo by Dylan Goodman
Members of the Boston Cendrawasih prep before their performance.
Photo by Dylan Goodman
Emil Massad ’25 conducts the Charles Revival and Friends performance. Massad organized the group and arranged the music for the performance.
Photo by Dylan Goodman
Anoushka Chander ’25 sings during the Charles Revival and Friends performance. The ensemble is composed exclusively of musicians from the Class of 2025.
Photo by Dylan Goodman
Onovughakpor Otitigbe-Dangerfield ’25 performs with the Charles Revival and Friends performance.
Photo by Dylan Goodman
Matthew Andrews ’25 plays the bagpipes during the Charles Revival and Friends performance.
Photo by Dylan Goodman
Paton Roberts ’25 applauds performers under the big tent.
Photo by Dylan Goodman
Roseanne Strategos ’25 (right) goes knees to stage alongside the Three Letter Acronym (TLA) improv group in Harvard Yard.
Photo by Dylan Goodman
Nathalie Beerelq (left) laughs during the TLA performance.
Photo by Dylan Goodman
Emily Huttin (right) makes a cyanotype in Science Center Plaza.
Photo by Dylan Goodman
Zack Li and his mother Linghui Li mold clay at an arts table in Science Center Plaza.
Photo by Dylan Goodman
Joshua Halberstadt ’25 (left) and Ava Maha ’28 perform the Act 1 Finale from Mozart’s “Don Giovanni” during the Harvard College Opera’s performance at Sanders Theatre.
Photo by Dylan Goodman
Dexter Suhn ’27 (right) performs with bassist Rocco Rizzi in Holden Chapel.
Photo by Dylan Goodman
Shriya Srinivasan (left), SEAS Faculty, and Shriya Srinivas from the Anubhava Dance Company perform.
Visiting Professor of History of Art and Architecture coleman a. jordan. Photo by Dylan Goodman
Arts & Culture
When talking drum becomes part of the dialogue
Visiting professor’s Venice Architecture Biennial project examines how to build renewable bridges between African, African diaspora communities
Nikki Rojas
Harvard Staff Writer
May 12, 2025
3 min read
Four years after curating st
Visiting professor’s Venice Architecture Biennial project examines how to build renewable bridges between African, African diaspora communities
Nikki Rojas
Harvard Staff Writer
3 min read
Four years after curating student work for an exhibition for the 2021 Venice Architecture Biennial, coleman jordan is back in Italy to construct his own project called “Recall and Response” at this year’s exposition.
The visiting architecture and art history professor’s pavilion structure — designed to be taken apart and reused — is meant to act as a talking drum that sparks dialogue among attendees of the showcase, which began Saturday and runs through Nov. 23.
“The pavilion is an instrument you can play. It’s a participatory experience,” jordan said, noting that “Recall and Response” examines the solidarity and commonality between African and African diaspora communities. “It’s a space for gathering, a space for people to collect themselves [and] have dialogues.”
The Morgan State University (MSU) professor is one of four visiting faculty at Harvard from Historically Black Colleges and Universities (HBCUs) supported by the Faculty of Arts and Sciences and the Harvard & the Legacy of Slavery Initiative.
“The pavilion is an instrument you can play. It’s a participatory experience.”
The pavilion structure is designed to be taken apart and reused.
Courtesy of coleman jordan
jordan, whose work focuses on spaces of the Black Atlantic and decolonizing the Black aesthetic, taught a course called “I Can’t Breathe” in the fall before refocusing on his scholarship.
In regard to “Recall and Response,” the scholar believes the two communities share common ground but that there is also disjuncture in communication.
“Because we’re from different places, [and have] different stories, different context, oftentimes our dialogue is not cohesive,” he said. “We’re not really understanding one another.”
Helping jordan with construction in Venice are students from MSU, and Tuskegee University, as well as his former Clemson University classmate Dan Harding, now director of the Community Research and Design Center and a professor at Clemson.
MSU’s drumline, affectionately known as “The Magnificent Marching Machine,” will march through Venice around jordan’s creation on June 20. The drum culture at HBCUs is significant, jordan noted, and can often play a role in the “identification of a school.”
“The idea is to use the drum as a metaphor for bringing people together,” he said.
Beyond the exhibition at the Biennale, “Recall and Response” will be a physical and symbolic representation of the work being conducted at the Pan African Heritage Museum, which is being built in Ghana. The museum currently exists as an interactive digital space that hopes to eventually house artifacts stolen from Africa during the colonial period.
In keeping with the Venice Architecture Biennial’s theme of “Repair, Regenerate, and Reuse,” jordan said he sees his creation as a way to repair dialogue between communities and regenerate those connections.
The pavilion has taken the reuse aspect of the theme literally, and will be given to a community space to repurpose.
jordan praised the support he received during his year at Harvard and highlighted the importance of sustaining partnerships between the University and HBCUs.
“I think that we can learn from each other’s history, no matter what it is,” he said. “Bridging matters, because we’re in this world together. That collaboration really helps to create that bridge, where our histories start to meld together, and we grow faster.”
Campus & Community
Using the best GenAI has to offer
Jessica McCann
Harvard Correspondent
May 12, 2025
5 min read
HUIT creates safe space to experiment, faculty share how they integrated it into their teaching
Generative AI took center stage when more than 300 educators and administrators gathered to explore, learn, and share best practices in teaching and learning at Harvard’s annu
HUIT creates safe space to experiment, faculty share how they integrated it into their teaching
Generative AI took center stage when more than 300 educators and administrators gathered to explore, learn, and share best practices in teaching and learning at Harvard’s annual Professional and Lifelong Learning Summit, held in early March.
Vice Provost for Advances in Learning Bharat Anand, the keynote speaker, centered his conversation on a topic that has surfaced repeatedly over the past year: generative AI and how it is being used across the University to support teaching and learning.
“We’re not seeing faculty use GenAI to replace their expertise. They’re using it most often to streamline routine tasks that often take up valuable time.”
Bharat Anand
“This isn’t just about AI getting smarter,” Anand said. “What changed with ChatGPT is that it became universally accessible. With a simple text box, anyone — not just coders — can now harness the power of these tools.”
That accessibility is prompting experimentation and reflection across Harvard’s classrooms. “We don’t need to wait for institutional directives or for things to be perfect,” Anand said. “Every person can use these tools since the distance between human and computer is shrinking. That’s why we’re seeing so many people start to test, explore, and adapt.”
When tools like ChatGPT first entered the public domain, faculty responses varied.
“In fall 2023, we saw both excitement and real apprehension amongst our community,” Anand noted.
To support exploration, Harvard University Information Technology, with input from the University-wide Generative AI Teaching and Learning working group, launched a secure GenAI sandbox for Harvard. The aim was simple: give faculty, staff, and students a space to play, prototype, and learn together.
The result? A growing set of grassroots innovations — and a new way to share them.
Learning from one another
Observing this interest in experimentation among faculty motivated Anand and his team to connect with faculty across Harvard’s Schools later in the academic year to understand the ways they’d used GenAI in their classrooms. One of the most visible efforts to emerge from this experimentation is the GenAI Faculty Voices Video Library. The project collects short interviews with faculty across the University who have integrated GenAI into their teaching.
“We wanted something useful and practical,” said Melissa Tarr, assistant director of programs at VPAL’s Harvard Institute for Learning and Teaching. “These videos offer concrete examples — quick hits that educators can learn from right away.”
The team asked each participating faculty member to identify a challenge they’d faced, a way GenAI was used to address this, and what they’d learned. Course planning, revising assessments, class discussions, grant editing, and student projects all surfaced as areas of early innovation.
“The faculty we interviewed were open-minded and thoughtful,” said Mary Godfrey, director of multimedia at VPAL. “They used GenAI to stretch their assignments and to test its boundaries. A number also deliberately showed students where the tools failed, as a way to sharpen critical thinking.”
It’s about augmentation, not substitution
Use cases include generating practice questions, building tutor bots, providing timely student feedback, or helping students learn prompt engineering.
Anand highlighted an important takeaway: “We’re not seeing faculty use GenAI to replace their expertise. They’re using it most often to streamline routine tasks that often take up valuable time. Whether it’s summarizing student responses, answering questions after hours, or drafting new practice problems, the goal is to free up energy for higher-impact teaching. This mirrors what we’re seeing in other sectors. The real value lies not in outperforming humans, but in ‘automating the mundane’: in saving time on things we already do — or don’t do — because they take too long.”
A community of learning
This ethos — of curiosity, reflection, and shared discovery — has come to define Harvard’s approach. Working groups have been in operation across the University, exploring the role of GenAI in research, administration, and pedagogy. The Teaching and Learning working group, chaired by Anand, continues to develop resources and track developments both inside Harvard and beyond.
“The video library is just one piece, and we’ll continue to add to it,” Anand said. “We’re trying to support thoughtful experimentation. At the same time, there is a strong need for GenAI literacy across the University, continued discussion on the ethics of its uses, and engaging in a more strategic conversation about what this all means for the role of educators.”
“The Faculty Voices Video Library illustrates the depth and breadth of creativity unfolding across Harvard’s campus,” said Provost John Manning. “I’m excited to see what further innovation lies ahead.”
Looking ahead: A campus-wide conversation
On May 13, Harvard will host its first University-wide symposium on the future of generative AI and its implications for the various activities of the University: research, teaching and learning, operations, and administration. Held at Harvard Business School’s Klarman Hall and sponsored by a coalition of University offices — including VPAL, the Office of the Vice Provost for Research, the School of Engineering and Applied Sciences, HUIT, the Harvard Library, and FAS — the half-day event will surface ideas and questions from across disciplines and schools.
“We’ve seen real momentum,” said Anand. “Now is a good time to take stock — to learn from each other, to ask hard questions, and to shape a path forward.”
Nghia Nguyen.Photo courtesy of Nghia Nguyen
Campus & Community
‘The goal is to understand who you are.’
Studying neurobiology gives Nghia Nguyen insights into ‘technical, tangible’ reasons for the things he does every day
Jacob Sweet
Harvard Staff Writer
May 9, 2025
7 min read
Part of the
Commencement 2025
series
A collection of features a
A collection of features and profiles covering Harvard University’s 374th Commencement.
For someone who studies the brain’s ability to predict future experiences, there is little about Nghia Nguyen’s life that could be described as predictable.
Nguyen, who graduated from the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences in November with a Ph.D. in neurobiology, was born in the very south of Vietnam, where his mother chopped banana leaves for work and his backyard was a rice paddy. “We grew up very poor,” he said. “Every day was a struggle to survive.” Their lives changed due to the American Homecoming Act, which allowed relatives of former American soldiers to immigrate to the U.S. with green cards. Nguyen’s grandfather, whom he’d never met, was an African American soldier in the Vietnam War. The law allowed applicants to prove their racial identity without a birth certificate. “When they saw my dad with an afro,” he said, “they were like, ‘This guy is clearly not full Vietnamese.’”
Nguyen and his family ended up in Burlington, Vermont. His mother packaged candy and his father took on a variety of jobs, like pumping gas and painting houses. They lived on North Street, along with seemingly all the other low-income and immigrant families in the area, about a mile north of downtown.
Though he and his sister attended schools that weren’t especially well-resourced, he said the teachers were kind and helped them learn English. His parents never made him work, and Nguyen and his sister focused their energy on getting perfect grades. “It wasn’t really even my parents’ expectations of me,” he said. “It’s just me observing the world around me and thinking, ‘How can I change that?’”
Nguyen secured full financial aid at Stanford, where he immediately felt himself playing catch-up. “Kids came in saying, ‘I’m going to skip three courses because I already know how to code,’” Nguyen recalled. “I was like, ‘What is coding?’” He picked his major, biomechanical engineering, because it seemed like the most practical and hardest option.
A year or two in, he felt like he’d caught up with his peers, which made him realize that his deficit had been because of an opportunity disparity rather than an innate skill difference. He also got encouragement from his sister to start doing research. “I know you don’t like to do stuff,” she said, “but just try it.”
He applied to several summer research positions for on-campus labs and received one offer. When he arrived, he remembers the professor telling him that he had not been the lab’s first choice. Nguyen didn’t care: “I was just glad they took me.”
“Neuroscience is a very self-fulfilling endeavor because the goal is to understand who you are.”
The job was to train mice on olfactory tasks. He would present an odor to a mouse, which he would direct toward a certain place to earn a reward. He learned to use a miniscope to get live images of mice brains as they performed different activities.
Conducting research felt like the first time his schoolwork actually applied to real life, and he loved it. “Neuroscience is a very self-fulfilling endeavor because the goal is to understand who you are,” he said. “And so doing these experiments gave me a very technical, tangible reason for the things I do every day. Why do I go seek food when I’m hungry? Why do I feel stressed in these moments? It gave me a very mechanistic reason for exactly why these things are happening.”
After graduating from college, Nguyen wondered if he should just try to make as much money as possible to help his mother retire. “But I really love neuroscience,” he said. “It was the only thing I ever really was passionate about.” Once he realized that he was paid for doing Ph.D. research and that he wouldn’t be burdening his family, the decision was easier.
At Harvard, Nguyen joined the lab of Mark Andermann, professor of medicine at Harvard Medical School, who studies how the body determines which sensory cues are attended to, learned, and remembered. For his dissertation, Nguyen studied what the brain is doing when daydreaming or not doing anything in particular. “We know which neurons are responsible for vision, for hunger, for thirst, for learning,” he said, “but we don’t really know what the neurons are doing when we’re really doing nothing — like sleeping and zoning out.”
Even when they’re not seemingly completing a discrete task, neurons still fire. The field has historically called this behavior “spontaneous activity,” but Nguyen doesn’t think the term is accurate. “It seems pretty taxing to fire all the time and just have it be random,” he said. “This activity is not spontaneous.”
To answer what the brain was doing during wakeful rest, Nguyen showed mice one of two videos of black and white blobs moving across a screen, recording the activity of 7,000 neurons in the process. Between the movies, Nugyen peered into their neuronal activity as they sat in a dark room.
Nguyen expected that the mice, after watching the videos, would play back the movies in their head during breaks as they experienced it the previous time. The hypothesis was consistent with the field’s traditional concept of replay or reactivation — that after experiencing something, you replay that experience in your head. Over time, through repeated exposures, it becomes easier to distinguish between different stimuli. Your experience looking at a painting for the 60th time is different than your first experience looking at it.
But Nguyen found that the mice’s brains didn’t repeat the experience of watching the movies; their brains actually predicted how they would experience the movies in the future. “It was the opposite of what we expected,” Nguyen said. “We never expected to have in our mind the representation of an experience that we have not experienced yet.”
The results shocked Nguyen and were novel enough to land in the scientific journal Nature. “Contrary to prevailing theories,” the paper states, “reactivations systemically differed from previous patterns evoked by the stimulus. Instead, they were more similar to future patterns evoked by the stimulus, thereby predicting representational drift.”
“Everything you will ever see ever, has already been played in your mind. It’s like before you saw me, I’ve already existed.”
Nguyen recognizes that there is more to be done to confirm his findings, and he hopes to continue working on similar problems in future research. He also wants to explore other observations from his project — like how the same neurons that processed the movie fired together even before mice watched it for the very first time.
The potential implications of that line of thinking are astounding. “Everything you will ever see ever, has already been played in your mind,” Nguyen said, smiling. “It’s like before you saw me, I’ve already existed.”
After an unpredictable upbringing, Nguyen is grateful to have wound up at Harvard. “Some people have bad experiences with their Ph.D., but every day, I thought, ‘I’m so privileged to do this stuff,’” he said. “There’s no way my parents would ever get this opportunity. I’m living such a surreal life.”
Work & Economy
Era of U.S. dollar may be winding down
Christy DeSmith
Harvard Staff Writer
May 9, 2025
8 min read
Economist Kenneth Rogoff’s new book entwines currency’s ascension, his own experiences, and looks at what looms ahead
It looks like the end of an era for the U.S. dollar.
In his new book “Our Dollar, Your Problem: An Insider’s View of Seven Turbulent Decades of Global
Economist Kenneth Rogoff’s new book entwines currency’s ascension, his own experiences, and looks at what looms ahead
It looks like the end of an era for the U.S. dollar.
In his new book “Our Dollar, Your Problem: An Insider’s View of Seven Turbulent Decades of Global Finance, and the Road Ahead,” Kenneth Rogoff looks back on the currency’s dominant run in global trade and central bank reserves for a host of other countries. Today, he argues, that lofty status is on the wane.
“My thesis is that the U.S. dollar is about to get knocked down a couple pegs,” said Rogoff, a professor of economics and the Maurits C. Boas Chair of International Economics. “It will still be first in global finance, because nothing is poised to fully replace it. The dollar just won’t be as unique as it once was.”
Written entirely before the 2024 election, the book weaves first-person reflections with a history of the U.S. economy and its currency topping a succession of challengers. As a teen chess pro in the late 1960s and early ’70s, Rogoff traveled to tournaments in the Eastern Bloc provided him with rare insight on America’s Communist rivals. As a visiting scholar at the Bank of Japan in 1991, he glimpsed a booming economy on the precipice of disaster. He went on to serve as chief economist at the International Monetary Fund in the early ’00s, the nascent days of Europe’s common currency.
“The book is not a memoir,” Rogoff said. “But I do link in anecdotes from my experiences with world leaders, policymakers, former students, and chess players.”
The Gazette met up with Rogoff in his office for a preview of the book’s personal tales and macroeconomic prophesy. The interview was edited for length and clarity.
Professor of Economics Kenneth Rogoff.
Photo by Martha Stewart
This release feels extraordinarily well-timed, given the recent sell-off of U.S. Treasuries and the dollar’s decline following President Trump’s April 2 tariff announcement. What events compelled you to revisit the dollar’s incredible rise and offer predictions for its future?
It wasn’t a single event. Based on my research, I thought the dollar peaked in its global footprint in 2015 and was in gentle decline. But I also thought this trend might accelerate. I was particularly concerned with our fiscal deficit and rising interest rates. I recently published a paper showing that if you look at the long history of interest rates, they tend to revert to trend.
I was also very concerned about the Federal Reserve losing independence. I actually wrote the first paper on the importance of central bank independence almost 45 years ago; it’s maybe my most famous paper. But in recent years, I started noticing rhetoric on both the left and the right about reining that in. Federal Reserve Chairman Jerome Powell wouldn’t get pushed aside out of the blue. It would take another crisis. During wartime, for example, central banks are commonly made subservient to the government.
That covers some of the internal pressures on dollar dominance. What about external factors?
We’ve been able to use economic sanctions in place of military intervention. It saves us lives; it saves us money. But dollar dominance also gives us access to financial data that no other country has. If you were to go to the CIA today, you would see somebody on a laptop instead of somebody like James Bond.
So there’s quite an appetite, particularly in Asia, to reduce the dollar’s grip. China couldn’t help but notice when the U.S. placed economic sanctions on Russia following its full-scale invasion of Ukraine. China, of course, has designs on Taiwan.
For most of us in the U.S., our currency’s almighty position isn’t exactly top of mind. Can you illustrate how dollar dominance impacts daily life for everyday Americans?
For one thing, we’re all paying lower interest rates. It’s not a huge amount. You don’t like paying 6 percent on your mortgage, but you’d dislike it even more if you were paying 7 percent. And for the national government, which owes $36 trillion, every additional 1 percent is $360 billion.
Another thing is that, in times of crisis like the pandemic or the global financial crisis of 2008, the U.S. has been able to borrow promiscuously. Interest rates do rise as our debt rises, but the effect is very gentle compared with the U.K. or France. If this privilege is lost, we will notice it.
Tell me about the book’s title.
The U.S. dollar used to be as good as gold. If you were a foreign country holding the equivalent to what is today hundreds of billions of dollars, as many Asian central banks do now, you could just take them to the U.S., and we would give you gold. But then President Richard Nixon decided, in 1971, that we weren’t going to do that anymore.
Leaders from around the world were in a state of shock. As a global financial incident, it was just as dramatic as the introduction of President Trump’s tariffs earlier this year. Nixon sent Treasury Secretary John Connally to meet with these leaders in Rome. They asked, “What do we do? Now that you’re not on gold, you can just inflate this stuff, and we’re stuck with it.” And Connally replied, “Well, it’s our dollar, but it’s your problem.”
What do Connally’s words call to mind for you today?
Connally’s remark captures the arrogance of American leaders that foreign leaders so often feel. I feel our role in the world comes with responsibility, and we should recognize that.
The book’s title is also ironic. After we went off gold, we lost a kind of price anchor. Nixon started beating up on Federal Reserve Chairman Arthur Burns as brutally as Trump beats up on Powell today. It just wasn’t in public; he was doing it in the Oval Office. We only know about it now because of the Watergate tapes. Burns got pressured into printing a lot of money. The result was the worst inflation the U.S. had seen since in a long while. So although Connally was saying “It’s your problem,” the resulting inflation proved a disaster for the U.S., too.
Other economies have emerged as challengers to U.S. power over the years. But you open the book with a surprising example, at least for those who came of age after the Cold War. You start with the post-World War II rise of the Soviet Union. Can you talk about that choice?
By the ’80s, it was becoming clear that the Russian ruble would not outpace the dollar. But in the ’60s and ’70s, we had no idea. I write about the different professors I met as an undergraduate at Yale, as well as textbooks by leading economists such as Paul Samuelson. Samuelson was convinced the Soviet economy would catch up to the U.S. The greatest economic historian of that era was Angus Maddison. He didn’t think the Soviet Union would catch up, but he thought it would do pretty well. These economists were not Marxists!
Later on, we didn’t know Japan would falter. We didn’t know Europe would fizzle. We never imagined the heights the U.S. dollar ultimately reached. My book hits these themes again and again.
How did your experiences as a globe-hopping teen chess master shape your views on the subject?
My professors at Yale talked about how great the Soviet Union was doing. But I had lived on my own abroad, primarily in the former Yugoslavia. I had visited some of my chess-player friends in their homes. Chess was a very big deal in the Communist bloc, so these players had privileged lives and nicer dwellings than the typical resident. But these nice dwellings consisted of little cement blocks in these humorless buildings. They barely had modern plumbing by U.S. standards. It made me very skeptical about Samuelson’s claim.
You write in this book that era of dollar dominance is in “late middle-age, but still in good health.” Is that still true in light of Trump’s second-term trade war?
Well, the dollar is starting to experience more serious health issues under Trump. When you’re an academic, the goal is never to write a book that’s true tomorrow. After coming to Harvard in 1999, I went for a walk across campus with former Faculty of Arts and Sciences Dean Jeremy Knowles. I’ll never forget what he told me. He said, “The perfect paper is one that everybody thinks is wrong, but in five or 10 years it’s proven right.”
You’ve achieved that in the past.
Carmen Reinhart and I were ridiculed in early 2009 when we presented a paper showing that recoveries from financial crises tend to be much slower and weaker than conventional recoveries. Of course that is exactly what happened. I had a similar experience in 2020 when my work suggested a deep problem in Chinese real estate.
My new book also contains some out-of-consensus forecasts that I believe will ultimately prove correct — on interest rates, inflation, and the role of the dollar. I don’t argue that dollar dominance will fall sharply tomorrow. But Trump has been an accelerant. He has been a catalyst. Parts of the world were already moving away from the dollar. Now they’re moving much faster.
Health
How young is too young? No such thing, apparently.
Specialist outlines impact of screen time on developing brains, from toddlerhood to teen years
Sy Boles
Harvard Staff Writer
May 9, 2025
6 min read
U.S. children aged 8 and younger spend 2½ hours a day on screens, with kids under 2 exceeding an hour each day, according to a recent report from Common Sense Media.
It’s data that
How young is too young? No such thing, apparently.
Specialist outlines impact of screen time on developing brains, from toddlerhood to teen years
Sy Boles
Harvard Staff Writer
6 min read
U.S. children aged 8 and younger spend 2½ hours a day on screens, with kids under 2 exceeding an hour each day, according to a recent report from Common Sense Media.
It’s data that Michael Rich, an associate professor of pediatrics at Harvard Medical School, finds deeply troubling.
Rich is the co-founder and director of the Clinic for Interactive Media and Internet Disorders at Harvard-affiliated Boston Children’s Hospital, where he works with young people whose online activities are interfering with their well-being. He sees digital media as an environmental health issue like clean air.
“We should definitely be asking the owners of these platforms to clean up their products, but we also have to help kids breathe right now,” he said. “We have to help them learn how to thrive in the environment we’ve got.”
Here’s how Rich describes the effect of screens at different stages of development:
Ages 0 ‒ 4
Screens don’t just attract our attention — they shape the structure of our brains.
“We are constantly making synaptic connections between our neurons,” Rich says. “When we use those connections, they get reinforced, but other connections are made and then get pruned away because we don’t use them so much.”
23%of children age 0 to 8 sometimes or often use a mobile device while eating at home.
The Common Sense report found that by age 4, more than half of children have their own tablet, and that 36 percent of 2- to 4-year-olds watch online videos every day. Rich has sympathy for their parents, many of whom are juggling multiple tasks. But, he said, the most important thing is to aim for the “richest way possible to build a brain.”
While synaptic connections are formed and pruned all through our lives, the brains of infants develop new connections faster. According to Harvard’s Center on the Developing Child, more than a million new neural connections are formed every second in the first few years of life — and these neural pathways lay the foundation for future development.
When babies and toddlers spend time on screens, their brains develop based on input that is at once highly engaging and absent of richer, more meaningful stimulus, Rich said, like the smell of their caregivers’ bodies or the touch of their skin.
“The real issue with screen time is often not what’s coming from the screen being toxic, but what they’re missing out on because they’re on a screen.”
Ages 5 ‒ 12
Over time, screens can “desensitize” children to the simpler sensations of the real world. “When they sit down at the dinner table and their parents are saying ‘How was your day?’ it just isn’t enough,” Rich said.
Rich also worries that much of what children consume on screens requires little to no engagement, a curated list of endlessly entertaining content activated by touch.
“It doesn’t demand that they contribute anything,” he said. “So the other piece is ‘I’m going to be fed stimulus’ as opposed to ‘I have to go out and find my stimulus.’ It doesn’t dull creativity; it just doesn’t give creativity space to happen.”
By age 8, nearly 1 in 4 children have their own phones, according to Common Sense Media, a statistic that Rich said poses new and different challenges.
“The lunchroom, the playground, the hallway between classes — these are the places where kids are individuals in a society of their own making, where they figure out who they like and don’t like, how to pick themselves up after challenges,” he said. “If that kid has in their pocket a phone in which mom can say, ‘How did you do on the math test? Do I need to talk to your teacher? What’s going on in the playground?’ they never get the opportunity to figure these things out for themselves.”
Even so, as state and local leaders move to ban or restrict phones in schools, Rich argues for a more nuanced approach.
“I think that we actually should be teaching kids to use these tools, just like we teach them to use the computer or pencil and paper,” he said. “If we ban phones from schools, we will not have any time or space in which kids are taught how to use these powerful tools effectively. An important part of using them effectively is knowing when they are not the best tool for the job and turning them off.”
Ages 13 and above
By the time kids reach high school, some have the social and emotional skills to regulate their own use of technology. For those who don’t, like the patients at Rich’s clinic, problematic internet use is almost universally a symptom of an underlying mental health condition or neurodivergence, typically depression, social anxiety, autism, or ADHD, he said. Helping teens moderate their internet use is really more about giving them tools to cope with those underlying challenges.
54%of teens ages 13-17 say they visit YouTube “almost constantly” or “several times a day”
Rich cautioned against thinking about problematic internet use as an addiction, though. “The therapeutic goal with addiction is abstinence,” he said. “The internet is a necessary resource. We need it to learn, to teach, to communicate, to connect.” Misuse “is driven by psychological, not physiological, drivers,” he said.
“We see the better analogy as binge-eating disorder, which is the most prevalent eating disorder. That’s the use of a necessary resource — food — but for psychological reasons, trying to fill that empty hole within. Our goal with binge-eating disorder and with problematic interactive media use is self-regulation, being able to use this tool in ways that are effective and productive.”
Rich is optimistic about a path forward for kids. His prescription: getting comfortable with boredom. That goes for adults, too.
“We’re so averse to boredom that we can’t get on an elevator without pulling our phones out,” he said.
He recommends that at any age, parents model healthy media habits, encourage non-screen activities, and have ongoing conversations about how to critique what kids see on their screens.
“Ultimately, whether we’re talking about television or smartphones or Gen AI, our goal is to help kids be critical thinkers, to be digitally literate in what they receive and also what they create and put out there.”
Harvard University, Collection Development Department. Widener Library; Illustration by Liz Zonarich/Harvard Staff
Health
When graphic design saves lives
Sy Boles
Harvard Staff Writer
May 9, 2025
4 min read
AIDS public health poster collection illustrates communication in a crisis
Today, much of the visual communication around public health is digital — in Instagram infographics, TikTok
AIDS public health poster collection illustrates communication in a crisis
Today, much of the visual communication around public health is digital — in Instagram infographics, TikToks, or YouTube videos. But in decades past, posters, printed out and pasted up in public, were a key way to spread messaging.
“People remember information better if it’s presented both visually and with printed messages,” said Amanda Yarnell, chair of the Chan Center for Health Communication, which helps online creators spread evidence-based health messages in ways that resonate. “Seeing something and reading something at the same time improves understanding.”
Harvard Library has digitized more than 3,000 posters related to a single major public health crisis: the HIV/AIDS epidemic. The posters come from numerous countries around the world and span roughly 1990 to 2004. The collection tells a story, said Yarnell, of what the public health establishment has learned about what messages work, and why.
Message, feeling, action
In the small area of a poster — and the limited time in which you might hope to catch someone’s attention — designers need to craft a single simple message. Too many words and you lose people.
“A good poster is one point and a feeling: something that the messenger wants you to remember, and then the feeling helps you remember it,” said Yarnell, who is also a lecturer on social and behavioral sciences at Harvard T.H. Chan School of Public Health. “And best-case scenario, there’s a route to more. It used to be a phone number, and then it became a website, and now it’s probably a QR code.”
China.
Harvard University, Collection Development Department. Widener Library. HCL, W542995_1
Italy.
Harvard University, Collection Development Department. Widener Library. HCL, W539985_1
South Africa.
Harvard University, Collection Development Department. Widener Library. HCL, W548279_1
Canada.
Harvard University, Collection Development Department. Widener Library. HCL, W463584_1
New Zealand.
Harvard University, Collection Development Department. Widener Library. HCL, W547869_1
Go big
Effective messages can be bold, eye-catching, or even provocative.
“Something that draws you in, something that makes you feel seen or resonates with you, gives you some kind of connection with the subject matter.”
Luxembourg.
Harvard University, Collection Development Department. Widener Library. HCL, W555087_1
Audience matters
“Often in the early days, there was a single campaign with a single message that was used in every situation,” Yarnell said. “Over time, we realized that you need multiple different campaigns for multiple different needs.”
Luxembourg.
Harvard University, Collection Development Department. Widener Library. HCL, W540084_1
Uganda.
Harvard University, Collection Development Department. Widener Library. HCL, W548336_1
India.
Harvard University, Collection Development Department. Widener Library. HCL, W543116_1
France.
Harvard University, Collection Development Department. Widener Library. HCL, W544068_1
Co-create the message
“For a long time, public health was really focused on, ‘We’ve gathered some expertise and we’re going to share it with you,’ as opposed to ‘We’re going to co-create expertise to help you make better decisions in your life,’” Yarnell said. The best way to make sure the message fits the audience, after all, is to make the audience a part of designing the message.
New Zealand.
Harvard University, Collection Development Department. Widener Library. HCL, W547888_1
South Africa.
Harvard University, Collection Development Department. Widener Library. HCL, W548280_1
United States.
Harvard University, Collection Development Department. Widener Library. HCL, W463631_1
Times have changed
Over time, researchers learned that positive, affirming messages are better for changing behavior than messages based in shame, stigma, or admonition, Yarnell said.
Australia.
Harvard University, Collection Development Department. Widener Library. HCL, W547913_1
Looking back at the posters in the collection is an exercise in remembering the past and preparing for the future, said Neal Baer, lecturer on global health and social medicine at Harvard Medical School.
“Condoms were the only things we had to prevent HIV back then. Now, it’s very different. We have PrEP [Pre-Exposure Prophylaxis]; we have antivirals that keep people alive. … These posters are outdated in the sense of the information they’re giving out.”
It is estimated that about 42 million people worldwide have died from HIV/AIDS since the virus first emerged in the 1980s. With modern preventions and treatments, it is possible to end transmission and prevent deaths, Baer said.
“We haven’t done a good job of preventing HIV transmission in the United States, especially since we have the ability to prevent it completely through ‘U=U,’” Baer said, referencing the “undetectable equals untransmittable” messaging strategy begun in 2016 aimed at changing the conversation around HIV/AIDS. “There should be no one getting HIV.
“This poster collection reaffirms that we need to not forget. … These posters are like gravestones of all the people who have died, and I don’t want them to have died in vain.”
Science & Tech
Know how those tech moguls want us to go to Mars? Ignore them.
Astrophysicist says they may have more money than you, but they don’t know anything more about future than anyone else
Nikki Rojas
Harvard Staff Writer
May 8, 2025
4 min read
Adam Becker.Photos by Niles Singer/Harvard Staff Photographer
Tech billionaires promoting space exploration and colonization as the so
Know how those tech moguls want us to go to Mars? Ignore them.
Astrophysicist says they may have more money than you, but they don’t know anything more about future than anyone else
Nikki Rojas
Harvard Staff Writer
4 min read
Adam Becker.
Photos by Niles Singer/Harvard Staff Photographer
Tech billionaires promoting space exploration and colonization as the solution to humanity’s problems should be ignored, says Adam Becker.
These CEOs have little to no expertise in engineering or astrophysics and have little to support their arguments beyond money, according to Becker, an astrophysicist, journalist, and author of the new book “More Everything Forever: AI Overlords, Space Empires, and Silicon Valley’s Crusade to Control the Fate of Humanity.”
“They think that money is some sort of metric that tells you how worthwhile somebody is and how smart they are, and that if somebody else has less money, that means that you don’t have to listen to them,” said Becker, who was joined at a recent Harvard Science Book Talk by Moira Weigel, assistant professor of comparative literature and faculty associate at the Berkman Klein Center for Internet and Society, and Max Gladstone, an award-winning science fiction and fantasy writer.
Becker earned a Ph.D. in computational cosmology from the University of Michigan in 2012. He said that as a child he also thought the future was among the stars.
“I didn’t question that assumption for a long time,” he told the audience. “As I got older, I learned more and realized, ‘Oh, that’s not happening. We’re not going to go to space and certainly going to space is not going to make things better.’”
In his book, Becker dissects the “baseless fantasies” promulgated by tech CEO billionaires, futurists, and philosophers. Each chapter features key figures — including philosopher Peter Singer, effective altruist William MacAskill, and futurist and former tech entrepreneur Ray Kurzweil — who believe they can optimize what comes next for humanity. Some, like Space X CEO Elon Musk, have the funds to pursue those beliefs.
“People were taking them seriously. That scares me and also I was deeply annoyed because if you know more about these areas, it becomes clear that they have no idea what they’re talking about.”
Originally, Becker believed the subcultures he focuses on in his book — rationalists, effective altruists, and those who believe in the singularity (the point at which tech essentially blends human and machine) — were “mostly harmless.” That belief changed over time.
“People were taking them seriously. That scares me and also I was deeply annoyed because if you know more about these areas, it becomes clear that they have no idea what they’re talking about,” he said.
Becker alluded to individuals, such as Silicon Valley tech billionaires like Musk and Jeff Bezos, who try futilely to “use their money to run as far as they like from their fears.” They have accumulated wealth because they need control in order to feel safe, he argued.
“You end up accumulating more and more money than you could ever possibly spend in one lifetime and more power than any one person should have,” he said. “That’s not enough and you need more.”
Becker also argued that there is “something very dualist and haunted” about the way the subjects of his book view the mind. Following the death of his father, Kurzweil began to explore the possibility that AI will one day be capable of collecting memories and replicating the human mind.
These people believe that “the body is this thing that the mind is unfortunately dependent upon rather than us being our bodies,” Becker said.
Max Gladstone (from left), Adam Becker, and Moira Weigel in conversation.
“Our bodies are not like space suits for our nervous systems or for our minds,” he said. “They are what we are and instead, there is this horror with the flesh that is just exuded by all of this rhetoric.”
While answering questions from the audience, Becker reiterated pointed criticisms of tech CEO billionaires who claim to have productive visions of the future.
“I think that they have something that sounds cool, that they believe in, that they think is a vision of the future, because they’re not used to thinking anymore. They’re used to vibing, and this might be why they’re so easily fooled into thinking that ChatGPT and other LLMs are actually thinking as opposed to producing extruded, homogenized-thought like products,” he said.
Campus & Community
New vice president, secretary of the University named to lead Office of the Governing Boards
Suzanne Glassburn. Photo by Grace DuVal
May 8, 2025
4 min read
Suzanne Glassburn will serve as chief administrative officer for Corporation, Board of Overseers
Suzanne Glassburn has been appointed vice president and secretary of the University, President Alan Garber announced Thursday.
New vice president, secretary of the University named to lead Office of the Governing Boards
Suzanne Glassburn.
Photo by Grace DuVal
4 min read
Suzanne Glassburn will serve as chief administrative officer for Corporation, Board of Overseers
Suzanne Glassburn has been appointed vice president and secretary of the University, President Alan Garber announced Thursday.
“A deeply experienced and widely respected senior university administrator, Suzanne is an individual of exceptional demeanor, diplomacy, and intellect,” Garber said. “Her leadership of the Office of the Governing Boards will advance and strengthen the critical work of both the Corporation and the Board of Overseers at a moment of great consequence for Harvard and for higher education.”
Prior to her appointment at Harvard, Glassburn spent 15 years at MIT, most recently as vice president and secretary of the Corporation, and previously as counsel in MIT’s Office of the General Counsel. Before her move to higher education, Glassburn was a partner at the Boston law firm Nutter, McClennen & Fish, LLP.
“I am deeply grateful to President Garber for the opportunity to serve an institution with such an incredible history of strong governance and respected leadership,” said Glassburn. “I look forward to joining a team committed to maintaining, upholding, and strengthening this essential partnership between administration and governance.”
As vice president and secretary of the University, Glassburn will serve as chief administrative officer of the governing boards, which are comprised of the Corporation and the Board of Overseers. As leader of the Office of the Governing Boards, she will set the priorities and vision for the office, which is responsible for supporting and offering guidance to the boards.
“It is a privilege to work with the dedicated individuals who serve on the Corporation and the Board of Overseers,” said Glassburn. “I look forward to providing guidance and counsel in support of their efforts to steer this venerable institution toward a future in which it continues to make profound and meaningful contributions to society.”
As secretary of the Corporation at MIT, Glassburn coordinated the activities and operations of a large governance body, as well as its standing and visiting committees. Her work included advising on governance issues, serving as liaison between MIT’s senior administration and governing board members, and overseeing the Office of the Corporation.
As vice president, Glassburn was a senior adviser and chief of staff to MIT’s president and a member of the senior team, which included the president’s direct reports. She also oversaw the Office of the President, federal relations, institute events, and the ombuds office.
Her work in the MIT Office of the General Counsel focused on academic and research collaborations, other contracts, governance, and policy. Notably, Glassburn collaborated with colleagues in Harvard’s Office of the General Counsel to structure and establish edX, Inc., a nonprofit online learning and Massive Open Online Courses (MOOC) provider.
At Nutter, McClennen & Fish, Glassburn represented public bodies and private businesses in a variety of industries, as well as nonprofits, and served in a number of leadership and administrative roles within the firm. Her practice areas included mergers and acquisitions, trademarks, intellectual-property licensing, and securities.
Glassburn will succeed Marc Goodheart, who announced plans in September to conclude his service as vice president and secretary of the University. Goodheart, who held the position for nearly three decades, will become senior adviser to the president and other University leaders while working to ensure a seamless transition in the Office of the Governing Boards.
“We are fortunate that Marc will continue to serve the University with his customary insight and wisdom as Suzanne steps into her new role.” said Garber.
Glassburn is a graduate of University of Pennsylvania Law School and received her undergraduate degree in English from Vanderbilt University.
Campus & Community
Redefining what’s possible
President Alan Garber (from left) with Tess Kim, founder of PeriPeach, which received a $75,000 award, and Harvard i-lab Managing Director Becca Xiong, and Senior Director Meagan Hall.Photos by Evgenia Eliseeva
Alex Parks
Harvard Correspondent
May 8, 2025
4 min read
President’s Innovation Challenge provides winners with support at the earliest stag
President Alan Garber (from left) with Tess Kim, founder of PeriPeach, which received a $75,000 award, and Harvard i-lab Managing Director Becca Xiong, and Senior Director Meagan Hall.
Photos by Evgenia Eliseeva
Alex Parks
Harvard Correspondent
4 min read
President’s Innovation Challenge provides winners with support at the earliest stages of their ventures
Helping mothers protect their bodies during childbirth, reimagining how hydrogen can be transported safely and affordably, and leveraging AI and robotics to transform the thousands-year-old process of hair braiding are a few of the 2025 Harvard President’s Innovation Challenge’s extraordinary winning ventures.
“At a time when so much is uncertain, the possibility of redefining what’s possible is not only a springboard to your own achievements, but also a gift to our community, our nation and our world,” said President Alan Garber. “Your willingness to pursue ideas, to take risks and to carve new paths to excellence reminds us all of the power of knowledge, and the importance and necessity of places like Harvard.”
The President’s Innovation Challenge is an annual competition for Harvard students and select alumni and affiliates pursuing ventures that are redefining what’s possible in their fields. During the Wednesday awards ceremony at Klarman Hall, President’s Innovation Challenge finalists pitched their ventures to a global audience of more than 2,000 in-person and virtual attendees. Winners received a share of $517,000 in non-dilutive funding, made possible by a gift from the Bertarelli Foundation, co-founded by Ernesto Bertarelli, M.B.A. ’93.
“Each year, the Harvard President’s Innovation Challenge showcases the incredible creativity and impressive drive of students from across the University,” said Bertarelli. “It’s been an immense honor to support these founders at the earliest stages of their ventures and see how they go on to make a positive impact to society.”
“Your willingness to pursue ideas, to take risks and to carve new paths to excellence reminds us all of the power of knowledge, and the importance and necessity of places like Harvard.”
President Alan Garber
President Alan Garber.
$75,000 award recipients
Gurus Inc. (Harvard T.H. Chan School of Public Health): Providing vulnerable populations with housing, education, mentorship, and support services.
Halo Braid (Harvard Business School, Harvard College, Harvard John A. Paulson School of Engineering and Applied Sciences): Building an AI-powered robotic hair braider that reduces braiding time from hours to minutes, empowering hair stylists to double their business.
PeriPeach (Harvard Medical School): Designing a medical device to prevent severe tears from childbirth.
Regatta Bio (Harvard Medical School): Developing cellular therapies to restore immune tolerance and prevent immune system-related diseases.
The Paal (Harvard Kennedy School): Improving financial outcomes for smallholder livestock farmers in India.
“Advocacy and awareness has always been a central part of PeriPeach, and I want to thank everybody here today,” said Tess Kim, founder of PeriPeach, after receiving the $75,000 prize. “This is for all the women who had to suffer with severe tears and for all the women who won’t have to.”
$25,000 award recipients
Adaptive Reader (Harvard College): Reimagining books so that every learner is able to engage with rigorous content, using AI to personalize languages and reading levels.
Brain Exercise Initiative (Harvard Law School): Preventing memory loss with cognitively stimulating exercises.
HydroHaul (Harvard Business School): Building a safer, more reliable, and cheaper solution for transporting hydrogen using a proxy carrier molecule.
Modulate Bio (Harvard Business School): Developing therapies to treat neurological disorders, including Essential Tremor, epilepsy, and anxiety.
Radiate Biosciences (Harvard Medical School): Creating a new colorectal cancer screening method with a blood test that delivers colonoscopy-level performance.
Ingenuity award winners
AIRQUA (Harvard Graduate School of Design, Harvard John A. Paulson School of Engineering and Applied Sciences): Transforming flood relief with air-generated water technology, delivering clean, safe water to families in urgent need during crises.
Pythia Diagnostics (Harvard College, Harvard John A. Paulson School of Engineering and Applied Sciences): Making a wearable device that predicts epileptic seizures by analyzing skin-released chemicals.
SAMI+ (Harvard T.H. Chan School of Public Health): Equipping health workers in the Democratic Republic of the Congo with AI-powered handheld ultrasounds, enhancing prenatal care.
SpiroSniff (Harvard College, Harvard John A. Paulson School of Engineering and Applied Sciences): Creating an affordable breathalyzer to detect lung cancer early, using sensors and AI for rapid, non-invasive, accessible screening.
Wyndergy (Harvard Extension School): Harnessing wind power to increase range for electric vehicles and eliminate range anxiety.
“Today is one of our favorite days of the year,” said Becca Xiong, managing director of programs and engagement at the Harvard Innovation Labs. “We get to celebrate bold ideas, real-world impact, and the remarkable people behind both. It takes vision, courage, and a lot of hard work to reach this stage — and even more to bring that vision to life.”
To learn more about the President’s Innovation Challenge finalists and winners, and watch a recording of the May 7 awards ceremony, visit the Harvard Innovation Labs website.
Sahil Chinoy.Photo by Dylan Goodman
Campus & Community
Interviewing experts wasn’t enough
Max Larkin
Harvard Staff Writer
May 8, 2025
5 min read
Stint as data journalist at NYT sends Sahil Chinoy on quest for even deeper dives into labor, politics, human behavior
Part of the
Commencement 2025
series
A collection of features and profiles
A collection of features and profiles covering Harvard University’s 374th Commencement.
Six years ago, Sahil Chinoy was a new hire at The New York Times, working at the intersection of journalism and data analysis. At 23, he was a graphics editor at the paper of record.
And it wasn’t enough. “I’d want to read the underlying paper,” Chinoy said. “You’re reading this research on the way home, on the subway, and feeling like, ‘I just don’t have the energy to really understand this — I’d have to do this full time.’”
In retrospect it’s clear to Chinoy how he was borne along — and repeatedly redirected — by his particular curiosity: about systems, abstractions, how things work.
He came to UC Berkeley in 2013 as an aspiring aeronautical engineer, but the shine quickly wore off. “When I went to my first class, all the other kids were super excited to get into the machine shop,” he laughed. “And I was like, ‘Oh, no: The part of this that I like is thinking about building things.’”
So engineering gave way to physics, and physics was in turn displaced by economics. After his year at the Times, he joined Harvard’s Economics Department as a doctoral candidate. He’s set to graduate from the Harvard Griffin Graduate School of Arts and Sciences later this month.
In papers for the National Bureau of Economic Research, he and his co-authors have studied big datasets in search of the sociopolitical patterns that structure American life, such as the influence of “zero-sum” thinking on American policy preferences and how military service in World War I drove Black veterans into the NAACP.
Along the way Chinoy may have benefited from the winding route he took to Harvard, drawing on advanced math, an interest in American politics, and the journalistic instinct for the timely investigation.
Chinoy’s distinctive approach has won him admirers among faculty collaborators and mentors.
Stefanie Stantcheva, his main adviser, is herself a rising star; she was awarded the John Bates Clark Medal for the top American economists under 40 just last month.
In written remarks, Stantcheva said it’s been “such a joy working with Sahil. He is super curious about new issues, but then also engages with them on a deep level.”
Vincent Pons of the Business School praised the “curiosity and ambition” Chinoy brought to their paper on neighborhood roots and political affiliation.
“Sometimes there are very big questions that you’re interested in, but it’s very unclear how you might study those questions,” Pons said. “Sahil is someone who — once he has a big question he’s after — he’ll find the data, and find the strategy, that is required to provide a convincing answer.”
“Sahil is someone who — once he has a big question he’s after — he’ll find the data, and find the strategy, that is required to provide a convincing answer.”
Vincent Pons
For Chinoy’s latest job-market paper, which found “substantial segregation” on the basis of ideology in American workplaces, that meant yoking together two enormous digital databases — voter rolls and the networking site LinkedIn. The work created a political-economic window on more than 34 million Americans, likely the largest such dataset ever compiled.
He and co-author Martin Koenen found that not only are there conservative- and liberal-aligned firms, but voters will measurably forgo some pay to work at a firm that reflects their values — or to avoid joining one that doesn’t.
Chinoy acknowledges that the interdependence of work and politics prompted decades of economic scrutiny before he ever came to Harvard. “A lot of what I am doing is I think addressing some of these long-standing questions with really modern econometric tools and with big data.”
“A lot of what I am doing is I think addressing some of these long-standing questions with really modern econometric tools and with big data.”
Sahil Chinoy
Three papers later, the work has helped him to a nuanced view of personal politics at work.
“In this research, I kind of seesaw between thinking that politics is now this defining form of identity, that for a lot of people shapes all kinds of decisions,” Chinoy said. “On the other hand, the labor market is also about people who want a paycheck, who want to put food on the table. And when a job pays less than another job — even if it’s more politically aligned with your views — that matters, too.”
For now, that’s the big question preoccupying Chinoy: what he calls “the interplay between political identity and political behavior and some of these economic forces,” like the labor market, immigration patterns, and racial coalitions.
And that interest has prompted one more evolution in Chinoy’s professional career. Trained as an economist, he’ll join the political science department at Stanford in 2026.
In the meantime, he has a postdoctoral appointment at Yale’s Program on Ethics, Politics and Economics, which will keep him in Cambridge for one more year with his partner, a public defender.
But first comes Commencement, which the Chinoys — his parents, his brother, and a couple of cousins — will attend ahead of a celebratory weekend trip to the Berkshires.
Asked if he can share any lessons for our polarized political moment, Chinoy remains — characteristically — in the interrogative mood.
“We started getting really good public opinion data in the mid-20th century, around the 1950s. And so we chart the rise of polarization from what might have been a particularly peaceful time in American politics, or at least, where there was less open conflict between different factions. Perhaps that was the anomaly.”
Professor of Medicine Joel Habener.Veasey Conway/Harvard Staff Photographer
Health
How just a fishing expedition helped lead to GLP-1
Story of game-changing therapy illustrates crucial role of fundamental research breakthroughs
Jacob Sweet
Harvard Staff Writer
May 8, 2025
4 min read
Part of the
Profiles of Progress
series
Sometimes an important
Sometimes an important discovery springs from a fishing expedition. In Joel Habener’s case, it was an actual one.
More than three decades after the discovery of GLP-1, the hormone has transformed the treatment of obesity, diabetes, and cardiometabolic disorders that affect more than a billion people worldwide. Habener, Svetlana Mojsov, Daniel Drucker, and Jens Juul Holst — scientists who played a crucial role in the hormone’s discovery and characterization — have received some of the biggest awards in science.
But more than three decades ago, when Habener, Massachusetts General Hospital and Harvard Medical School investigator emeritus, set up an experiment that helped lead to the discovery, this outcome was far from clear.
“It’s just been one surprise after the next,” Habener said. “It’s amazing to me.”
The unique pancreas of an ugly fish helped accelerate a revolution in modern medicine.
Back in the late 1970s, Habener’s goal was to identify possible prohormones — precursors of hormones — for the pancreatic hormones glucagon, which raises blood sugar, and somatostatin, which inhibits both insulin and glucagon.
He and MGH investigators P. Kay Lund and Richard H. Goodman decided to use recombinant DNA gene cloning to isolate these prohormones from the pancreases of rats, but they ran into a problem. The National Institutes of Health, which helped fund this fundamental research, had declared a moratorium on recombinant DNA research in warm-blooded animals as scientists evaluated ethical and safety concerns of the new technology.
“The solution to the problem,” Habener said, “required a fishing expedition.”
A member of his lab knew a commercial fisherman who had provided research specimens for other scientists. The anglerfish was raised as a possibility “because the anglerfish is a trash fish,” Habener said. “We throw them back. And they’re big, and they’re ugly.”
It was also cold-blooded and therefore exempt from the NIH moratorium.
The anglerfish turned out to be a boon for Habener’s research. While endocrine and exocrine tissues exist together in a rat’s pancreas, the two types of tissue are separated in anglerfish — with endocrine cells in a marble-sized organ called the Brockmann body. The separation made isolating the mRNA, and the peptide hormones and their precursors, easier.
After extracting mRNA from the Brockmann bodies, Habener and his team were surprised to find that glucagon and somatostatin were embedded in larger proteins that later cleaved into their active forms.
“The eureka moment,” as Habener puts it, was when they discovered that in the larger precursor protein proglucagon, there was a signal peptide, an intervening peptide, a peptide that was homologous to mammalian glucagon, and then a second GLP-related peptide later revealed to be GLP-1.
It took many more fundamental breakthroughs before this discovery could translate into therapeutic use. Mojsov, now a research associate professor at Rockefeller University and then a member of MGH’s endocrine unit, identified the biologically active form of GLP-1, known as GLP-1(7-37).
Holst, a University of Copenhagen professor, discovered that GLP-1 acts as an incretin hormone, stimulating insulin secretion in response to food.
Drucker, a clinician scientist at Sinai Health’s Lunenfeld-Tanenbaum Research Institute — and a former member of Habener’s MGH research group — uncovered more of GLP-1’s physiological actions and helped translate GLP-1’s therapeutic benefits to drugs.
The impact of GLP-1 drugs might seem like a given today, but Habener knows that some of the federally funded developments that led there were far from preordained.
“I think the word is serendipity,” he said. The unique pancreas of an ugly fish helped accelerate a revolution in modern medicine.
Nation & World
Pompeo warns against U.S. pulling back from global leadership role
Mike Pompeo (far right) with Meghan O’Sullivan and Nicholas Burns.Stephanie Mitchell/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
May 7, 2025
6 min read
Former secretary of state offers insider accounts of efforts on Middle East, Iran, China, view of Ukraine war
Former Secretary o
Pompeo warns against U.S. pulling back from global leadership role
Mike Pompeo (far right) with Meghan O’Sullivan and Nicholas Burns.
Stephanie Mitchell/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
6 min read
Former secretary of state offers insider accounts of efforts on Middle East, Iran, China, view of Ukraine war
Former Secretary of State Mike Pompeo says the U.S. appears to be pulling back from its leadership role on the world stage and warns there is no other nation that can step in as the champion of global democracy if America walks away.
Pompeo, J.D. ’94, sat down on Monday for a closed-door talk at Harvard Kennedy School about his time as the nation’s top diplomat and spoke candidly about his efforts with Israel and the Middle East, Iran, China, and his views on Russia’s war with Ukraine.
The event was part of the American Secretaries of State Project, a collaboration between the Program on Negotiation at Harvard Law School and the Belfer Center’s Future of Diplomacy Project at HKS. Over the years, past secretaries including James A. Baker III, Henry Kissinger, Madeline Albright, Condoleezza Rice, and Hillary Clinton have come to these sessions to share insights into some of their greatest diplomatic challenges.
In the wide-ranging discussion, Pompeo detailed the negotiations behind the 2020 Abraham Accords, a series of agreements normalizing relations between Israel and the United Arab Emirates, Bahrain, Morocco, and Sudan.
He said there were three essential components to getting these deals done: first, demonstrate the U.S.’ unwavering support for Israel; second, make clear Iran is a bad actor in global politics and the central impediment to improved Mideast relations; and lastly, convince the Arab Gulf nations that the U.S. would not throw them under the bus if things fell apart.
Pompeo also defended his close relationship with Saudi Crown Prince Mohammed bin Salman even after a CIA assessment found he was behind the 2018 murder of Washington Post journalist Jamal Khashoggi. Pompeo, who Monday called the killing “horrific,” said he felt it was important to U.S. long-term strategic interests to remain close with Saudi Arabia.
Asked about the Israel-Palestinian conflict, Pompeo, now at the Hudson Institute, a Washington, D.C., think tank, said it’s “very unlikely” there will be a two-state solution in the near or medium term.
“If America doesn’t lead, the world is forlorn. There’s nobody. … For good or for bad, it sits on our shoulders, and we should own that, and we should be happy to go lead in that way.”
Mike Pompeo
While in Congress, Pompeo had been a vocal critic of the 2015 Iran nuclear deal negotiated by Secretary of State John Kerry, believing it gave Iran too much leeway to enrich uranium, a necessary step in the production of a nuclear weapon. Less than two weeks after he became secretary of state, the U.S. withdrew from the deal.
Even now, with Iran’s power diminished from a decade ago, it’s “an absolute imperative” that the U.S. stand firm on its policy of “no enrichment” because there’s no way to ever be absolutely certain Iran wasn’t doing so secretly. “If they can cheat, they will,” said Pompeo.
“As good as our intelligence agencies are, as wonderful as our collection is, [Iran is] a big country, and they have demonstrated their ability to foil our efforts to actually know what’s going on,” he said, adding, “If the Iranians get any closer than they are, you’ll have proliferation in the region.”
Pompeo was joined in the discussion by Ambassador Nicholas Burns, Roy and Barbara Goodman Family Professor of the Practice of Diplomacy and International Relations at HKS; Robert Mnookin, Williston Professor of Law, Emeritus, at HLS; Meghan L. O’Sullivan, director of the Belfer Center and Jeane Kirkpatrick Professor of the Practice of International Affairs at HKS; and James Sebenius, Gordon Donaldson Professor of Business Administration at Harvard Business School.
Before becoming secretary of state, Pompeo served as CIA director from 2017‒2018. While a supporter of the agency, he believes it remains too focused on Middle Eastern counterterrorism after the Sept. 11, 2001, attacks.
One of the CIA’s lingering “shortcomings,” he said, is that it does not spend enough time on economic intelligence, which puts the U.S. at a great competitive disadvantage with China given that President Xi Jinping “has been at war with the United States for 40 years — economically.”
He called standing by as China moved to weaken democracy in Hong Kong following the 2019‒2020 protests “one of my great failures” as secretary.
In regard to Russia, Pompeo said he has not been surprised by the actions of Vladimir Putin. It makes sense that the Russian president remains fixated on Ukraine and righting what he perceives as a historic wrong done to Russia as he continues to “chip away” at Europe’s borders.
“It’s intrinsic to who he is,” Pompeo said, which is why “we should never give an inch of Europe to him, and I regret that it appears that we’re headed that way.”
Pompeo rejected the notion that the U.S. can’t afford to help countries like Ukraine and should cut back its defense of democratic values around the world.
“That’s what saddens me in my own political party, is that too many people who know better, who know how important this is,” have been unwilling to do the hard work and explain to the country “why it’s in America’s best interest to be the world’s leader, that the benefits far exceed the costs,” said Pompeo, who served in the U.S. Army before attending the Law School.
A more isolationist approach to foreign policy is the easier political argument to make to voters, but the U.S. will regret it in the coming decade if we fail in this moment to lead on the global stage, he said.
“If America doesn’t lead, the world is forlorn. There’s nobody. The Japanese can’t do it. The Australians can’t do it. The Indians won’t do it,” said Pompeo. “For good or for bad, it sits on our shoulders, and we should own that, and we should be happy to go lead in that way.”
Campus & Community
5 faculty members named Harvard College Professors
Photos by Veasey Conway/Harvard Staff Photographer, Grace DuVal, and Stephanie Mitchell/Harvard Staff Photographer; photo illustration by Liz Zonarich/Harvard Staff
Eileen O’Grady and Kermit Pattison
Harvard Staff Writers
May 7, 2025
9 min read
Recognized for excellence in teaching in fields ranging from geometry to politics
5 faculty members named Harvard College Professors
Photos by Veasey Conway/Harvard Staff Photographer, Grace DuVal, and Stephanie Mitchell/Harvard Staff Photographer; photo illustration by Liz Zonarich/Harvard Staff
Eileen O’Grady and Kermit Pattison
Harvard Staff Writers
9 min read
Recognized for excellence in teaching in fields ranging from geometry to politics
Five faculty members have been awarded a Harvard College Professorship for excellence in undergraduate teaching, in fields ranging from high-dimensional geometry to comparative politics. Hopi Hoekstra, Edgerley Family Dean of the Faculty of Arts and Sciences, announced the recipients on May 6. They are:
Denis Auroux, Herchel Smith Professor of Mathematics
Michael Smith, John H. Finley Jr. Professor of Engineering and Applied Sciences
Karen Thornber, Harry Tuchman Levin Professor in Literature and Professor of East Asian Languages and Civilizations
Yuhua Wang, Ford Foundation Professor of Modern China Studies
“I am delighted to recognize these five outstanding colleagues for their contributions to teaching, mentorship, and research,” Hoekstra said. “Their passion, rigor, and creativity inspire our students every day, giving them the opportunity to ask big questions, explore new ideas, and grow as thinkers and scholars. I am grateful for their extraordinary commitment to our students and our educational mission.”
The Harvard College Professorship was launched in 1997 with a gift from John and Frances Loeb. Professors hold the title for five years and receive support for a research fund, summer salary, or semester of paid leave.
Denis Auroux.
Veasey Conway/Harvard Staff Photographer
Illuminating ‘deep connections’ across math
Auroux is a pure mathematician who has spent his career studying ethereal domains such as high-dimensional geometry, in which some shapes are too abstract to be drawn on a blackboard. He finds much more tangible rewards when it comes to teaching.
“I am really happy when I feel that I’ve explained something to a student in a way that suddenly they get it,” Auroux said. “The process of seeing knowledge being acquired, I just love that.”
Auroux has taught at Harvard since 2018. Educated in France, he previously held positions at the Ecole Polytechnique, MIT, and Berkeley. Among his classes is the legendary “Math 55,” a fast-paced course for advanced first-year students.
He described his teaching style as classical — lectures, a “massive amount” of homework, and office hours — and he still prefers an old-fashioned chalkboard. He seeks to guide students toward a deeper understanding of mathematics from multiple perspectives, including algebra, geometry, and analysis. Over the course of the year, the class revisits the same facts from different branches of the discipline.
“There are deep connections that run across different areas of math,” he said. “It’s very beautiful when you get to illuminate that in a class.”
Auroux himself still seeks those deep connections. He studies the geometry of abstract spaces that are not encountered in everyday life, but are subjects of keen interest for mathematicians and theoretical physicists. His research interests include symplectic geometry, low-dimensional topology, and mirror symmetry.
“I’m still trying to understand the same questions I was trying to understand 10 years ago,” said Auroux. “I’m just changing what it means to understand. I have understood certain things, and now I realize there’s more I don’t understand. Maybe mathematicians are a bit obsessive about that.”
Christina Maranci.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Putting images first to promote curiosity
Maranci, an art historian with a focus in pre-modern Armenia, likes to begin her classes with images — perhaps a 7th-century Armenian manuscript depicting the Annunciation, or photographs from fieldwork in Eastern Turkey — and let her students first experience the image, then learn to understand it.
“One of the wonderful things about working with art and visual culture is that you can really confront them with things before they know what they are, and they just look,” Maranci said. “Then you teach them to ask questions about what they’re looking at. For me, it’s a really helpful way of teaching and it also promotes curiosity.”
Maranci’s area of expertise falls at the intersection of art, architecture, and material culture of medieval Armenia. She teaches courses on all aspects of Armenian culture and history, from liturgical textiles to art and literature.
For Maranci, teaching is a “whole-body” experience. She doesn’t read from notes, choosing instead to walk around the room as she lectures, welcoming questions and drawing individual students into lively, public dialogue.
She vividly recalled her own undergraduate struggles — grappling with material that seemed easily understandable to her peers. That experience, she said, informs the way she teaches today.
“I really like to talk them through things,” Maranci said. “I’m putting myself in their shoes and I want to break things down in a way that makes everybody feel that they can learn this stuff. Even when it’s obscure 7th-century Armenian Church architecture, at bottom it’s all knowable, and that’s something I try to get across.”
Michael Smith.
Harvard file photo by Grace DuVal
Engaging, hands-on, with problems
For Smith, the surest route to learning is doing — engaging with real problems, solving technical challenges, and wrestling with ethical dilemmas.
“It’s one of my passions,” he said of teaching. “I especially enjoy working with our undergraduates. I try to make it as hands-on and engaging as possible and connect it to the issues that the students are thinking about at the current time.”
Smith has spent decades thinking about education. He began teaching at Harvard in 1992 and spent 11 years as dean of the FAS. He is writing a book about teaching.
A prime example of his hands-on approach is “CS 32: Computational Thinking and Problem Solving,” an introductory course that enrolls some 300 students. On the first day, students install the Integrated Development Environment (a software interface with tools for computer programmers)on their laptops so they can work on problems simultaneously with the professor. In the final weeks, each student presents an independent project. Some students designed a program to turn the popular online game Wordle into a two-player version; another wrote a program to scrape recipes from the Internet and then suggest what to cook for dinner that night based on the ingredients on hand in the kitchen.
“I want them to have a foundation on which they can start to learn for themselves and become self-sufficient,” said Smith.
He applies a similar philosophy to his upper-level class, “Critical Thinking in Data Science,” in which students grapple with the ethical implications of ever-more-powerful information technologies. The class features two-week “sprints,” exercises in which students build deepfakes and facial recognition programs — and contended with the social consequences of their creations. Smith summed up the dilemma: “Yeah, I can build it, but should I build it?”
Karen Thornber.
Harvard file photo by Grace DuVal
Creating a space where all perspectives are welcome
Thornber, a cultural historian of East Asia, strives to make her classroom a space where all perspectives are welcome, and where students feel comfortable sharing their insights, even when discussing difficult topics such as gender-based violence, mental health stigmas, or end-of-life care.
Thornber said co-chairing the FAS Civil Discourse Advisory Group and becoming the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning last year made her realize the need to foster this environment with greater intention.
“It’s made me realize the importance of being attentive to students’ own inclination to self-censor, or to come to premature consensus,” Thornber said. “There’s a need for being really intentional about this and being really explicit with the students. If we all come in with the same opinion, that’s great, but we’re going to tackle other opinions as well, because it’s really important that they understand the range of opinions on a difficult topic.”
Thornber’s own scholarship spans the medical and health humanities as well as the environmental humanities, gender justice, indigeneity, and transculturation, as related to the literatures and cultures of East Asia. Her research scope also includes South and Southeast Asia, well as Africa, Europe, and North America. She has taught a range of undergraduate courses, from first-year seminars on gender justice and literature of pandemics to general education courses on mental health and the arts. This fall she will teach a new course, “HUMAN 2: Introduction to the Medical and Health Humanities.”
She said creating a “transformative experience” for students gives her work meaning. For her, that means helping students feel connected to each other and breaking down some of the silos that separate students from different backgrounds so they can all engage in lively and productive classroom discussions.
“I believe very strongly that the humanities provide our students with unique and invaluable information, insights, and perspectives into how we can best make sense of and ameliorate some of our most complex global challenges,” Thornber said. “Not only is it exciting to work with students on increasing their knowledge of global challenges, but also to work with them on how they might ultimately render this knowledge into impactful action. Nurturing the hopefulness, excitement, and creativity that students bring to the table — it’s really a privilege and an honor to be able to do that.”
Yuhua Wang.
Stephanie Mitchell/Harvard Staff Photographer
Learning along with his students
Wang likes to build his political science courses around intellectual debates, to show his students that there is always another way to look at the world. Sometimes this means assigning readings and structuring class discussions to reflect contradictory views.
“I ask them, ‘What do you think?’” Wang explained. “We can challenge the reading and challenge each other. I think that debate form is really useful for getting to the bottom of things. At the end of the conversation, we usually gain more understanding of the issue but also change our previous view about the question.”
Wang’s area of expertise is Chinese politics. He has written extensively about state-building in China from the seventh to 20th centuries and is currently doing comparative research to see how China and Europe diverged politically after the year 1000. The undergraduate courses Wang teaches regularly include “Government and Politics of China” and “Comparative Political Development,” and he is part of a rotation of faculty who teach “Foundations of Comparative Politics.”
Wang said his favorite part of teaching Harvard undergraduates is how often they challenge him intellectually — something that he says is “the best thing that can happen to a professor.” He sometimes presents a provocative argument on purpose, inviting students to push back. More than once, their responses have led him to change his own viewpoint.
“One thing I really want to emphasize to them is I’m learning with them — in this class, we are exploring something together,” Wang said. “I think that’s really important, because I don’t want them to stop learning after this class, or after Harvard. I want them to realize even people my age are still learning, and that I can learn from them.”
Arts & Culture
He studies dogs’ faces. She studies their brains.
Harvard canine researcher Erin Hecht (left) and photographer Elias Weiss Friedman (right) of “The Dogist” Instagram account join Faculty Dean David Deming for a talk at Kirkland House.Photos by Dylan Goodman for the Harvard College Dean of Students Office
Eileen O’Grady
Harvard Staff Writer
May 7, 2025
5 min read
‘Dogist‘ Instagr
Harvard canine researcher Erin Hecht (left) and photographer Elias Weiss Friedman (right) of “The Dogist” Instagram account join Faculty Dean David Deming for a talk at Kirkland House.
Photos by Dylan Goodman for the Harvard College Dean of Students Office
Eileen O’Grady
Harvard Staff Writer
5 min read
‘Dogist‘ Instagram photographer, Harvard scientist swap insights on human-canine bond
Inside a sound- and scent-proof room at Harvard’s Canine Brains Lab, photographer Elias Weiss Friedman tapped a hammer on the floor near his hand as Sasha, the Harvard University Police Department’s community engagement dog, watched attentively. When Friedman feigned injury, pretending to hit his thumb and crying out in pain, the black Labrador looked briefly to Officer Steve Fumicello, her handler, before rushing to Friedman and licking his face. The moment was part of an experiment used regularly to assess the empathy of dogs in the lab.
“Some [dogs] react like that, some of them couldn’t care less,” explained Erin Hecht, assistant professor in the Department of Human Evolutionary Biology, who runs the Canine Brains Project. “In the real test, the person does this three times, and we had a couple of dogs actually take the hammer away.”
Friedman, founder of popular social media account “The Dogist,” visited Hecht’s lab last week. Friedman has photographed more than 50,000 dogs while Hecht uses a different kind of imagery — MRIs — to study the science behind the beloved pet.
“I’m OK, I was just joshing,” Friedman reassured Sasha, after the experiment, while petting her ears. “Thank you for being so empathetic and caring, because if that were to happen in real life I would need your love.”
Hecht and Friedman later discussed the way they each approach dogs visually in a fireside chat at Kirkland House moderated by Faculty Dean David Deming, Isabelle and Scott Black Professor of Political Economy at Harvard Kennedy School and Professor of Education and Economics at Harvard Graduate School of Education.
“They make great photographic subjects because they’re 100 percent candid,” said Friedman, whose new book, “This Dog Will Change Your Life,” is forthcoming. “You can look at a dog and see the expression on their face and know that they’re being 100 percent honest, and there’s something very great about that.”
Hecht said MRI scans allow her to explore the question many dog owners have wondered at some point: What is going on inside their head?
“You can see all kinds of things, signatures of fearfulness, or aggression, or trainability, something we might think of as cognitive capacity or ability to learn, and differences between breeds that might relate to their historical functions,” Hecht said. “I still get shivers when we get a dog in the scanner and their brain image comes up for the first time. It’s like, ‘Wow, there’s a brain in there. That is the dog, all of its emotions and thoughts and plans and desires, we’re looking at it right now.’”
“You can look at a dog and see the expression on their face and know that they’re being 100 percent honest, and there’s something very great about that.”
Elias Weiss Friedman
She said that in science, it’s always possible to invest time in a study only to find no significant results. But that hasn’t been the case with her dog research, likely because of the remarkable variability in canine brains and their close ties to behavior. Hecht’s lab is actively recruiting dogs for research studies, particularly seeking dogs with behavioral issues related to early life stress or trauma. They are also looking for children ages 7 to 12 and their dogs to participate in a study exploring the bonds between kids and their pets.
Friedman said dogs are like “furry icebreakers” that have helped him meet tens of thousands of interesting people as part of his work.
“Before you get a dog you know your neighbor, and after you get a dog you know your neighborhood,” Friedman said. “There is this force of community and socialization when your dog needs to go out, you just end up meeting like 10 people. That’s very real.”
Sasha, the Harvard University Police Department’s community engagement dog.
Hecht said dogs have been bred to be good at making friends with people.
“The ability to form a bond with people is the most fundamental thing that they’ve evolved. We are their social partners. Their natural place in the world is within human society. They’re adapted for our world,” Hecht said. “Then humans have developed different lineages of dogs. Some breeds need to be defensive and territorial in order to protect a family or a flock of sheep. Others need to do a job that’s more interactive with the environment. It’s this huge range of cognitive styles.”
During the Q&A, students asked Friedman and Hecht a range of questions: “Do dogs pick favorites within the household?” (Hecht: They have favorites for different activities); “Are dogs judgmental?” (Hecht: They can intuit when people’s intentions are not friendly); and “Do people really look like their dogs?” (Friedman: Yes).
When asked if there were any dogs that stood out from the thousands he has photographed, Friedman recalled Pudding, a pit bull mix bearing the scars of past abuse, whom he photographed back in 2013 when his Instagram account was barely a month old.
“Until then I had been going about it as the joke, like, ‘Wouldn’t it be funny to photograph dogs?’” Friedman recalled. “This was a pivotal dog because it made me realize this project was much more profound. Dogs make us laugh and cry and there’s some beauty and sadness, and it’s important that I share all of it.”
Arts & Culture
Hooking first-years on the arts and humanities
Dean Sean Kelly (second from left) pictured here with professors who will be teaching introductory arts and humanities courses in the fall and spring. They include Lauren Kaminsky (from left), Raquel Vega-Durán, Neel Mukherjee, Spencer Lee-Lenfield, Laura van den Berg, Karen Thornber, and Moira Weigel.Stephanie Mitchell/Harvard Staff Photographer
Eileen O’Grady
Harvard Sta
Dean Sean Kelly (second from left) pictured here with professors who will be teaching introductory arts and humanities courses in the fall and spring. They include Lauren Kaminsky (from left), Raquel Vega-Durán, Neel Mukherjee, Spencer Lee-Lenfield, Laura van den Berg, Karen Thornber, and Moira Weigel.
Stephanie Mitchell/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
6 min read
Professors rethink students’ introduction to humanities with nine new courses
To counter the nationwide problem of declining enrollment in these fields, the initiative aims to engage more first-year students in the studies.
While Kelly attributes declining enrollment in part to a lack of emphasis on the subjects in American high schools, one Harvard statistic gave him pause: While about 12 percent of first-years arrive on campus interested in pursuing arts and humanities, about half end up changing their minds by the time they declare their concentrations.
“That was the thing that really struck me,” Kelly said. “The kinds of introductory courses that we’re teaching don’t grab our students. That was the issue that I wanted us to have conversations about.”
There are exceptions to the enrollment decline — courses in Art, Film & Visual Studies and Theater, Dance & Media, as well as creative writing and music performance, are in high demand among students. But Kelly believes the “Canon Wars” of the ’80s and ’90s — debates over which major texts define disciplines like English or art history — impacted the design, and appeal, of many introductory humanities courses. While these debates broadened our understanding of what counts as a “great work,” Kelly said, they also made it harder to curate a definitive list of must-reads to introduce the subjects.
“The idea that you’re studying something ‘great’ is motivating for a student, and that it was harder for us to say about any text that it is great had an effect on the kinds of courses that we were able to design and teach,” Kelly explained. “That makes it hard for a first-year student, since they can’t gain any sense of what matters in the field.”
“I hope these courses meet the students where they are and really help them understand the intrinsic value of what we do. I hope they are great courses that change their lives.”
Sean Kelly, dean of arts and humanities
Kelly took inspiration from the Department of Philosophy, which has increased its number of concentrators nearly fivefold since 2006 after shifting its goals from preparing students for future Ph.D.s to engaging undergraduates in fundamental questions about human beings and the universe. Questions like these can be beneficial regardless of a student’s future career path.
The department introduced intro courses like Professor Samantha Matherne’s “Phil 129: Kant’s ‘Critique of Pure Reason,’” which garnered an enrollment of 80 students, and Professor Gina Schouten’s “Phil 16: Sex, Love, and Friendship,” which attracted 120 students the first time it was taught.
Building on this model, and after a series of conversations with faculty last fall, Kelly put out a call for introductory humanities course proposals. He received nearly two dozen. Ten were selected, nine of which will launch in the 2025-2026 academic year.
Next spring Moira Weigel, assistant professor of comparative literature, will teach “Humanity, Technology, and Creation”; professor of linguisticsKathryn Davidson will teach “Language”; and incoming assistant professor of comparative literature Spencer Lee-Lenfield will teach “Translation and the Craft of Reading Carefully: A World Literature Introduction.”
John T. Hamilton, William R. Kenan Professor of German and Comparative Literature, will teach “HUM 17: The Human Sciences: Fundamentals and Basic Concepts” next spring. The course offers an overview of the methods, questions, and tools that define the humanities in much the same way gateway courses like LS50 or CS50 do in other disciplines. Students will tackle metaphor and metonymy, epistemology and ontology and the structures of language, and grapple with philosophical ideas such as consciousness, perception, and moral freedom, all ideas that define what it means to study human culture.
“It does give you that ground plan,” said Hamilton. “It says, OK, you’re interested in the humanities? This is what we do, this is how we grapple with all sorts of things. Then you may have a better idea of where you want to delve into for your following time at Harvard.
“In the same way you need to know how momentum works to study physics, and how cells reproduce to study biology, you need to know what a metaphor is, what realism is, and what consciousness is to do the humanities.”
Laura van den Berg, senior lecturer, and Neel Mukherjee, associate senior lecturer in creative writing in the Department of English, will co-teach “HUM 9: Reading for Fiction Writers” in the fall. The course introduces students to a range of texts, including Anton Chekhov, Ursula Le Guin, and Octavia Butler, to help them understand how reading shapes writing, and begin to write their own stories.
“We are trying to bring together the critical side of the English Department, which trains students in how to close-read, understand, and analyze the text, with the creative-writing side, which trains in technique and craft,” Mukherjee said. “We wanted to marry the two to show that good writing is always dependent on being a good reader.”
“Our ability to tell our own story to ourselves and to others, to absorb other people’s stories — that’s so foundational to who we are and our identity,” van den Berg agreed. “A richer, more rigorous, nuanced understanding of how story works, how we work on story, and how story works on us, is incredibly important as a human practice.”
For Kelly, the intro course initiative is not just about increasing enrollment, but about building a more inviting and engaging humanities culture for new students. He hopes to underscore the humanities’ inherent value, not just their instrumental use. As he put it, it’s the difference between reading Shakespeare’s “King Lear” to analyze tyranny, versus reading it to explore what it means to be human.
“I want these introductory courses not just to be about the instrumental value of the disciplines, but about their intrinsic value. I want them to focus on why it matters for all of us engaged in the human project to learn how to read great literature, to think about great philosophy, to encounter great art,” Kelly said.
“I hope these courses meet the students where they are and really help them understand the intrinsic value of what we do. I hope they are great courses that change their lives.”
Campus & Community
How the Cold War continues to shape German identity
Stephanie Mitchell/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
May 7, 2025
6 min read
Addie Esposito’s thesis — based on interviews with lawmakers in the Bundestag — examines ‘persistent divide’ between East and West
Part of the
Commencement 2025
series
A collection of features and profiles covering Harvard University’s 374th Commencement.
Addie Esposito ’25 grew up with stories about life in Germany.
“My mom was there for two years just after the Berlin Wall fell,” Esposito said. “She actually has three tiny pieces of the Wall, one for me and each of my sisters.”
At Harvard, Esposito’s fascination with German culture, and the complicated legacy of its post-World War II split into East and West, deepened. A double concentrator in government and German, she was able to fully immerse herself in these interests while completing an internship in the German parliament last summer. Working at the Bundestag also allowed Esposito to launch an ambitious project studying how the Cold War continues to shape German identity today.
“She completed this rich, rich analysis of the persistent divide between East and West,” said her thesis adviser, Daniel Ziblatt, the Eaton Professor of the Science of Government and director of the Minda de Gunzburg Center for European Studies. “When Germany unified in 1990, the expectation was that this divide would quickly pass. What’s remarkable is that it has endured for more than a generation and become a permanent feature of German political culture. … In some ways, it’s analogous to regional divides in the U.S. after the Civil War.”
Esposito first visited Germany with her mother at age 5. “I was just fascinated by the language,” she recalled. “My mom said I started saying German words in my sleep, just some basics like ‘blau,’ which is blue, and ‘Brot,’ which is bread.”
In middle school, German was the obvious choice for Esposito’s foreign language elective. In high school, the Raleigh, North Carolina, native completed a two-week exchange program in Frankfurt, Germany, and interned at a nonprofit run by her mother’s friend in a small town near the French border.
As a College first-year, Esposito enrolled in Ziblatt’s “Democracy: Breakthroughs and Breakdowns,” drawn to the professor’s expertise in authoritarianism and democracy in the U.S. and in Europe — Germany in particular.
“I thought, ‘This person is at the intersection of all my interests,’” Esposito recalled. “I kind of clung to him like a barnacle ever since.”
“I’d love to be the ambassador to Germany. I would be thrilled to work for the State Department. I would like to use my German no matter what.”
Ziblatt helped Esposito land her position with a member of the center-left Social Democrat Party representing part of Hamburg, Germany. This provided her with access to the full chamber, which totaled more than 700 legislators at the time. “It meant I could go anywhere I wanted in the Bundestag unaccompanied,” said Esposito, whose internship was made possible by the Center for European Studies.
One area, however, was strictly off-limits. Mainline German political parties have constructed what they call “a firewall” against cooperation with the far-right Alternative for Germany (AfD) party, which is most popular in the country’s eastern states.
“For the parliamentarian with whom I was working, that meant zero contact,” Esposito explained. “Therefore, the AfD was initially excluded from my interview pool.”
In the end, the former Harvard International Review co-editor in chief surveyed 183 parliamentarians to learn about their backgrounds as well as the contours of their identities. Esposito also did face-to-face interviews (in German) with 48 members, including 17 members from the former Soviet-controlled German Democratic Republic (GDR). Once her internship was complete, she moved to secure what Ziblatt characterized as “rare” research interviews with two members of the AfD.
“It’s pretty common for students to rely on pre-existing surveys for their theses,” he said. “But in this case, she used her own interviews to dig a lot deeper into how people think about their lives — and how those lives relate to politics and history.”
Esposito’s approach, with its unusual focus on political elites, uncovered regional attachments more pronounced than what pollsters had found with the broader German public. She discovered that more than half the parliamentarians from the former GDR still identify more as East German than anything else.
The identity proved somewhat less central for parliamentarians who grew up after East Germany’s Peaceful Revolution of 1989. “But it was still incredibly high,” Esposito said, with more than 40 percent of Millennial and Gen Z members from the region selecting East German as their primary identity.
A different pattern was observed with parliamentarians hailing from the part of the country once occupied by the U.S., Great Britain, and France. Just 9 percent of those Esposito surveyed identified as primarily West German. More than half identify as broadly German. More than a quarter identify as broadly European.
“West German identification isn’t really a thing,” Esposito said.
Esposito drew on her interviews to advance what she calls an “underdog” theory of East German identity. “It’s strengthened both by adversity and triumph,” she said. “That makes the identity incredibly durable.”
Outsiders can be too quick to connect the phenomenon to the East’s persisting socioeconomic disadvantages, Esposito noted. “There’s also this sense of positive distinctiveness rooted in feeling responsible for reunification. People said things like, ‘We earned this freedom — we’re the reason the wall fell.’”
The thesis also builds on previous findings concerning the East/West divergence in regard to 20th-century history. The East German dictatorship, founded in 1949, positioned itself as an anti-fascist state and distanced itself from Nazi crimes, she said.
In fact, lawmakers with the AfD (both from the former GDR) made statements Esposito interpreted as trivializing the Holocaust — by comparing it to COVID-19 restrictions, for example.
This dynamic helps explain the nuances Esposito recorded in how East and West Germans express national pride. “West Germans’ responses often followed a pattern of ‘I am not proud to be German, but I am proud of Germany’s achievements,’” she writes in her thesis. “East Germans often dropped the hedging language.”
Those from East Germany — comprising 16 to 26 percent of the overall population, depending on how the region is defined — also spoke of experiencing discrimination, a phenomenon Esposito corroborated in interviews with lawmakers from the West.
“She had this incredible access to the highest level of politics in the country,” Ziblatt observed. “And she used it to engage politicians in these long conversations about what it means to be German.”
Next up for Esposito is a master’s in public policy at the Hertie School in Berlin, where she’ll have the opportunity to complete public policy internships while perfecting her German. “By the time I finish at Hertie, I want to be fluent,” Esposito said.
Longer term, she hopes to earn a Ph.D. in political science. “Honestly, my dream position would be to do what Professor Ziblatt does now,” she said. “But I’m also interested in the public policy side of things. I’d love to be the ambassador to Germany. I would be thrilled to work for the State Department. I would like to use my German no matter what.”
Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
The boy had just lost his dad to cancer. Jett Crowdis listened.
Alvin Powell
Harvard Staff Writer
May 6, 2025
4 min read
Medical School graduate found his calling in a connection forged while serving as camp counselor
Part of the
Commencement 2025
series
A collection of fea
A collection of features and profiles covering Harvard University’s 374th Commencement.
An encounter with grief during summer camp set Jett Crowdis on the path to a medical career.
While a Harvard undergraduate, Crowdis — who will graduate from Harvard Medical School this spring — served as a counselor at a camp for children whose parents have cancer. There, he met a 9-year-old boy whose father had died of pancreatic cancer just weeks before.
It was “a sad opportunity to be with someone going through such a challenging time in their life,” Crowdis said. “In later years, I got a chance to talk with him a bit more about his experience and he opened up about it.”
Before that experience, Crowdis knew he liked science, but wasn’t sure the best way to make a career of it. His experience at Camp Kesem, run by a national organization with chapters at several colleges, put a human face on the medical needs he knew were out there.
“My favorite aspect of research is when I get to ask questions that no one else has asked, with data that no one else has.”
“That was the first time that I got to be with someone through a very challenging experience in their life and just listen to what they were experiencing,” Crowdis said. “That was very meaningful to me. I realized that was something that I wanted in a future career, and I think medicine naturally merged that with my interest in science.”
Crowdis, who grew up in Florida, entered Harvard College thinking he would study molecular biology, but during his sophomore summer he worked in the lab of Louise Foote Pfeiffer Professor of Cell Biology Joan Brugge, who encouraged him to learn coding in order to better analyze his research results. Crowdis spent a summer teaching himself the Python coding language and began taking computational biology courses in the fall.
“I just absolutely loved it,” Crowdis said.
Crowdis graduated from the College in 2019 but made the decision to apply to medical school late. He took two gap years in the lab of Associate Professor of Medicine Eliezer Van Allen, also a Camp Kesem alum. Van Allen’s lab at the Dana-Farber Cancer Institute seeks to use computational biology to analyze genomic data from cancer patients, probe cancer’s molecular origins, investigate resistance to cancer therapies, and use genomics to guide clinical decision-making.
Crowdis used his computational skills to advance projects in the Van Allen lab, analyzing data from a prostate cancer genomic study. He was the first author of a Cell Genomics paper that highlighted the benefits of a broad-based experimental framework that engaged study participants as partners who freely share biological samples, clinical information, and details of their cancer experience. The work showed that the model, called the Metastatic Prostate Cancer Project, could break down barriers to treatment and care.
“My favorite aspect of research is when I get to ask questions that no one else has asked, with data that no one else has,” Crowdis said. “That’s the core aspect of research that I love the most, really, the exploration.”
After Crowdis entered HMS in the fall of 2021, he kept in touch with Van Allen, continuing work on some projects. When he expressed an interest in learning immunology, Van Allen connected Crowdis with Arlene Sharpe, Harvard’s Kolokotrones University Professor. In the Sharpe lab, Crowdis investigated how a technique called checkpoint blockade that harnessed the immune system to fight cancer can go wrong, causing potentially dangerous adverse reactions.
“He’s very thoughtful, very interested and engaged, he’s a critical thinker,” Van Allen said. “That’s a pretty unique combination to have. He really wants to be as critical and as keen as he possibly can.”
Though he has amassed considerable research experience, Crowdis is still exploring how large a role that research will play in his career. He matched with Yale New Haven Hospital and will head there after Commencement to begin a residency in internal medicine. The move will also give him a chance to rejoin his wife, Sruthi Muluk, a Harvard College classmate now in an obstetrics and gynecology residency at the University of Connecticut.
“It’s fascinating,” Crowdis said of internal medicine, “and also gives you time to sit and be with patients in the same way that I enjoyed the process at Kesem.”
Adam Cohen.Niles Singer/Harvard Staff Photographer
Health
Tracking precisely how learning, memories are formed
Yahya Chaudhry
Harvard Correspondent
May 6, 2025
5 min read
New technique may offer insights for new therapies to treat disorders like dementia
A team of Harvard researchers have unveiled a way to map the molecular underpinnings of how learning and memories are formed, a groun
Tracking precisely how learning, memories are formed
Yahya Chaudhry
Harvard Correspondent
5 min read
New technique may offer insights for new therapies to treat disorders like dementia
A team of Harvard researchers have unveiled a way to map the molecular underpinnings of how learning and memories are formed, a groundbreaking new technique expected to offer insights that may pave the way for new treatments for neurological disorders such as dementia.
“This technique provides a lens into the synaptic architecture of memory, something previously unattainable in such detail,” said Adam Cohen, professor of chemistry and chemical biology and of physics and senior co-author of the research paper, published in Nature Neuroscience.
Memory resides within a dense network of billions of neurons within the brain. We rely on synaptic plasticity — the strengthening and modulation of connections between these neurons — to facilitate learning and memory.
A combination of fluorescent labeling and cutting-edge microscopy allowed the researchers to illuminate synaptic behavior at unprecedented resolution.
Credit: Pojeong Park
Synapses, or the junctions where neurons communicate, lay the groundwork for every memory we form, from a childhood melody to a loved one’s face to what we ate for breakfast.
In their new paper, the team detailed their new technique, dubbed Extracellular Protein Surface Labeling in Neurons (EPSILON), which focuses on mapping the proteins vital for the transmission of signals across synaptic connections in the brain.
These specific proteins are called AMPARs and are considered key players in synaptic plasticity, the process that allows the brain to adapt and reorganize itself in response to new information.
Utilizing sequential labeling with specialized dyes, EPSILON enabled the researchers to monitor these proteins’ movements at high resolutions. Traditionally, understanding such detailed microscopic phenomena has required more invasive methods. Using EPSILON to observe AMPARs’ behavior in neurons represents a significant scientific advance.
This work was undertaken by several members of Cohen’s lab, including Harvard Griffin GSAS student Doyeon Kim and postdoctoral scholars Pojeong Park, Xiuyuan Li, J. David Wong-Campos, He Tian, and Eric M. Moult, as well as scientists from the Howard Hughes Medical Institute.
A combination of fluorescent labeling and cutting-edge microscopy allowed the researchers to illuminate synaptic behavior at unprecedented resolution. The technique’s precision was akin to shining a spotlight on some of the brain’s most intricate functions, allowing the team to monitor the synaptic interactions critical for learning.
As synaptic changes of specific memories came into view with greater clarity, patterns started to reveal rules governing how the brain decides which synapses to make stronger or weaker when storing a memory.
Prior research into synaptic processes often lacked such granularity, making EPSILON’s insights particularly valuable for future explorations into diseases like Alzheimer’s, marked by synaptic dysfunction that results in memory and learning impairment.
As synaptic changes of specific memories came into view with greater clarity, patterns started to reveal rules governing how the brain decides which synapses to make stronger or weaker when storing a memory.
“Our most important breakthrough is our method that can map the past history of the synthetic plasticity in the living brain,” Kim said. “We can look at the history of the synaptic plasticity, studying where and how much of the synaptic potentiation has happened during a defined time window during the memory formation.
“By mapping the synaptic plasticity over time at multiple time points, we can truly map the dynamics of the synapses,” Kim added. “We’ll also be able to apply this to different kinds of memories that have different patterns of synaptic plasticity.”
The technique’s first application has already yielded intriguing results. By applying EPSILON to study mice undergoing contextual fear conditioning — a process that helps animals associate a neutral context with a fear-inducing stimulus — researchers were able to demonstrate a correlation between AMPARs and the expression of the immediate early gene product cFos, a signal that tells us when brain cells are active.
These findings suggest that AMPAR trafficking is closely linked to enduring memory traces, or engrams, within the brain, where specific neurons become activated following learning experiences.
Cohen credits the significant and sometimes unexpected role basic science can play in fueling progress with enabling their study to succeed.
“The HaloTag technology, which is used to label proteins, was based on a gene discovered in 1997 by a group of scientists in Ireland who were studying a soil bacterium, which had an unusual ability to break down pollutants,” Cohen said. “It’s a generations-long arc from the basic research characterizing the natural world to making discoveries that can make human health better. We really need to support the entire arc to make progress.”
Looking forward, Cohen is eager to see how EPSILON can be further applied to study numerous cognitive phenomena and potentially improve therapeutic strategies targeting memory impairments.
“We’ve already distributed the molecular tool to labs around the world who are now starting to use these tools to explore how synaptic strength is regulated in their favorite question and context,” he said.
This work was partially supported the National Institutes of Health.
Arts & Culture
Schlesinger exhibit turns spotlight on largely invisible past
Denison House Chinese girls basketball team, 1931.O.H. Steir
Sy Boles
Harvard Staff Writer
May 6, 2025
4 min read
Students, archivists collaborate to tell deeper story of Asian American women’s history
Among the artifacts on display in a new exhibition at the Schlesinger Library are photos of Ainu and Visaya
Schlesinger exhibit turns spotlight on largely invisible past
Denison House Chinese girls basketball team, 1931.
O.H. Steir
Sy Boles
Harvard Staff Writer
4 min read
Students, archivists collaborate to tell deeper story of Asian American women’s history
Among the artifacts on display in a new exhibition at the Schlesinger Library are photos of Ainu and Visayan women who were displayed as “living exhibits” at the 1904 St. Louis World’s Fair.
The women’s names are not known. Their images have survived because they were included in the archives of Jessie Tarbox Beals, one of America’s first female photojournalists. But their stories are now being revisited as part of “Illuminate: Contextualizing Asian American Women’s Stories Through the Archives.”
“Asian American history is oftentimes invisible, given the population and the history,” said Victor Betts, the curator for collections on ethnicity and migration at the Schlesinger Library. “It’s pushed to the margins. That’s also reflected in the archives.”
Ainu woman and child at the 1904 World’s Fair.
Jessie Tarbox Beals, Courtesy Schlesinger Library
Visayan girls at the 1904 World’s Fair.
Jessie Tarbox Beals, Courtesy Schlesinger Library
The exhibition, on display through January, presents materials spanning 150 years and asks viewers to examine their own assumptions about Asian and Asian American women’s roles in history.
The show was created in conjunction with a spring undergraduate course called “Asian American Women’s History in the Schlesinger Library,” which Betts co-taught with Erika Lee, Bae Family Professor of History and the Carl and Lily Pforzheimer Foundation Director of the Schlesinger Library.
“It’s a model of co-teaching and co-creation, of research and learning, that we hope will serve as a model for other classes,” Lee said.
Students used the archival material to consider the ways Asian and Asian American women have been forgotten, made hypervisible, or both, as were the women displayed at the World’s Fair.
“We had a whole week on erasure,” Lee said, laughing. “Like, where are they?”
Christian D. Topinio ’27 researched Beals’ photos for his final project.
“[The women] were objects to study, potentially objects of cultural curiosity,” Topinio said. “There’s a really interesting idea in these photos where you’re ascribing colonial hierarchies among these people, buttressing colonial hierarchies abroad.”
Betts said that in more contemporary collections, Asian American women tell their own stories on their own terms, like the donated archives of famous chefs and cookbook authors Grace Zia Chu and Madhur Jaffrey.
“Other women, earlier in history, in the 19th and 20th centuries, didn’t have that luxury,” he said. So he and the students went looking.
Sophia Wang ’25 researched the 1874 court case of Ah Fong, a Chinese woman who was detained at the Port of San Francisco. She and about 20 other detained women and girls, age about 17 to 28, filed writs of habeas corpus on their own behalf.
Their legal action also contributed to the 1875 Supreme Court case Chy Lung v. Freeman, in which the court ruled that only Congress, not states, had the power to regulate immigration.
“As someone who’s Chinese American and whose parents immigrated to the United States, when I read her case, I was in tears,” Wang said. “They were legal pioneers, although their stories still remain untold.”
Although there was little concerted effort to collect and preserve Asian American women’s stories at the time, archivists found Asian American women’s stories throughout local history and Harvard’s history.
Siok-An Chiu Wu, Wai Tsu New Kuo, and Manik Kosambi appear in Radcliffe College yearbooks in 1919 and 1922.
The exhibit places Asian American women’s photos, political posters, comic books, and zines in the context of the Chinese Exclusion Act, Japanese American internment, the Civil Rights era, and anti-Asian violence in the years of the COVID-19 pandemic.
Betts wanted to play with the exhibit’s title, “Illuminate,” as part of the display. He commissioned artwork by Greater Boston Taiwanese-American artist Shaina Lu to accompany the archival material. Her translucent illustrations, placed over the windows, allow sunlight to filter into the gallery.
“In so much of Boston Chinatown’s organizing history, Asian American women lead the charge for justice,” said local artist Shaina Lu.
Betts is working to expand Schlesinger’s collections of Asian and Asian American women’s materials. But for now, he said, what’s missing is part of the point. It’s an opportunity to ask why Asian American women’s stories have been marginalized in the first place, and how our understanding of American history would change if they weren’t.
“Asian American history is American history,” Betts said, “and so it should have the same level of seriousness and value that we understand U.S. history, collectively, to have.”
“Illuminate: Contextualizing Asian American Women’s Stories through the Archives” is on display through Jan. 23 in the Lia and William Poorvu Gallery of Schlesinger Library.
Professor Arthur Kleinman gave his final “Future of Medical Anthropology” seminar on April 29. Photos by Grace DuVal
Campus & Community
Long career in search of ‘how to improve the human condition’
Christy DeSmith
Harvard Staff Writer
May 5, 2025
4 min read
Medical anthropology pioneer Arthur Kleinman takes a bow
A long career bridging medicine, social science, and the humanities has
Long career in search of ‘how to improve the human condition’
Christy DeSmith
Harvard Staff Writer
4 min read
Medical anthropology pioneer Arthur Kleinman takes a bow
A long career bridging medicine, social science, and the humanities has left Arthur Kleinman with one critical insight.
“Care, critically understood and practiced, matters most,” he told a packed lecture hall last week. “This is at the center of whatever claim I can make to wisdom and truth.”
Kleinman, M.A. ’74, a psychiatrist whose many titles include Esther and Sidney Rabb Professor of Anthropology, plans to officially retire next year after a total of nearly 50 years at Harvard. But his work in the classroom ended Tuesday with the final meeting of his “Future of Medical Anthropology” seminar.
The occasion drew nearly 200 current and former students to Sever Hall, with dozens more joining via Zoom. Five former students also testified to Kleinman’s impact as a teacher, author, mentor, and moral anchor committed to building cross-cultural understanding and advancing well-being.
“The gift that he leaves us with is the idea that knowledge is not only linked to patents and businesses,” offered Adams House Faculty Dean Salmaan A. Keshavjee, Ph.D. ’98, who also serves as director of the Center for Global Health Delivery at Harvard Medical School (HMS) and professor of Global Health and Social Medicine in the Department of Global Health and Social Medicine (GHSM). “It’s linked to a better understanding of how to improve the human condition.”
The final seminar drew nearly 200 current and former students to Sever Hall. He was joined by Jim Yong Kim, Salmaan Keshavjee, Anne Becker, and Davíd Carrasco.
Kleinman, who is also a professor of medical anthropology in GHSM and professor of psychiatry at HMS, first landed at Harvard with his wife, Joan, in the fall of 1970. With support from the National Science Foundation, the Stanford-trained M.D. came to do a comparative study of medical systems across cultures.
“I quickly figured out that for me, anthropology was a suitable way forward,” Kleinman explained.
He taught Harvard’s very first course in medical anthropology in 1973. He left in 1976 for an associate professorship at the University of Washington, but the expert on health care in Chinese culture was back in Cambridge by 1982, now in a senior position split between the Faculty of Arts and Sciences and HMS.
“And that is the position I will be retiring from in July 2026 when I formally retire, and from which today — 43 years later — I deliver this, my final lecture,” Kleinman said.
He honored the contributions of the late Harvard social medicine/psychiatry professor Leon Eisenberg and former students including the late Paul Farmer, M.D/Ph.D. ’90, the celebrated co-founder of Partners In Health. Kleinman also name-checked a long line of staffers and faculty assistants who over the decades helped build the medical anthropology program.
“We’ve had about 100 doctoral students, 25 of whom are M.D./Ph.D.’s; more than 250 postdoctoral fellows, including researchers from much of the world; over 50 M.A. students; dozens of students from the Chan School of Public Health and other Harvard Schools; hundreds of medical students; and thousands of undergraduates,” he said.
Veterans of the program praised more than Kleinman’s intellectual rigor and moral mentorship. His influential body of work also figured prominently. In the final class, former World Bank President Jim Yong Kim, M.D. ’91, Ph.D. ’93, who co-founded Partners In Health with Farmer, testified to the career-altering discovery of Kleinman’s “Patients and Healers in the Context of Culture” (1980).
Anne E. Becker ’83, M.D./Ph.D. ’90, the Medical School’s dean for Clinical and Academic Affairs and its Maude and Lillian Presley Professor of Global Health and Social Medicine, spoke to the inspiration provided by “The Soul of Care” (2019), Kleinman’s account of navigating the healthcare system as a family caregiver from Joan’s Alzheimer’s diagnosis until her death in 2011.
“This book has become my touchstone as a clinician — and quite frankly, in my responsibilities as an educator, mentor, and colleague,” Becker said.
Nation & World
When foreign governments took aim at universities
Scholars look to historical examples for insights amid current U.S. tensions
Christy DeSmith
Harvard Staff Writer
May 5, 2025
6 min read
“Little did we know then how important this issue would become to the very institution in which we are meeting today,” said Sven Beckert.Photos by Stephanie Mitchell/Harvard Staff Photographer
Scholars look to historical examples for insights amid current U.S. tensions
Christy DeSmith
Harvard Staff Writer
6 min read
“Little did we know then how important this issue would become to the very institution in which we are meeting today,” said Sven Beckert.
Photos by Stephanie Mitchell/Harvard Staff Photographer
Recent government demands on U.S. universities have some scholars searching for the right historical analogue for insights.
“I’ve been thinking about this budding conflict between the state and universities as possibly a replay of the 1950s” and the McCarthy era, said William C. Kirby, T.M. Chang Professor of China Studies in the Faculty of Arts and Sciences and Spangler Family Professor of Business Administration at Harvard Business School. But, he suggested, events that occurred outside the U.S. provide more useful parallels.
Kirby and other Harvard faculty with expertise on higher ed crackdowns in various national contexts came together on a recent panel hosted at the Minda de Gunzburg Center for European Studies (CES). Stories emerged of governments in other countries muzzling student speech, placing universities under receivership, or hobbling institutions with bureaucratic red tape.
The event, offered as part of the center’s Democracy and Its Critics Initiative, had been in the works since December. “Little did we know then how important this issue would become to the very institution in which we are meeting today,” said moderator Sven Beckert, Laird Bell Professor of History.
The history starts in the heart of Berlin, began Kirby, author of “Empire of Ideas: Creating the Modern University from Germany to America to China” (2022). The University of Berlin, founded in 1810, was the world’s premier research university. It was the first dedicated to the creation as well as the transmission of knowledge. It pioneered the concept of academic freedom for students and faculty. It also placed liberal arts, rather than professional training, at its core.
“It became the model for all great research universities,” said Kirby, who served as FAS dean from 2002 to 2006.
Sugata Bose (from left), Sven Beckert, William C. Kirby, Laura Jakli, and Daniel Ziblatt.
As late as 1930, he noted, the University of Berlin — known today as Humboldt University — was the world’s most respected institution of higher learning. But its reputation collapsed with the rise of the Nazi movement, with its book burnings, mass firings of Jewish professors, and curbing of curriculum deemed insufficiently German.
Some of South Asia’s great universities were patterned after the University of Berlin, said panelist Sugata Bose, Gardiner Professor of Oceanic History and Affairs. He spoke of “the Humboldtian project” being implemented at his own alma mater — Kolkata’s Presidency College, founded in 1817 — “with later echoes in Dhaka, Lahore, Aligarh, Allahabad, and Bangalore.”
The decline of those situated in India started in 2016, Bose said, when supporters of Prime Minister Narendra Modi launched what he characterized as “an unbridled attack on India’s best universities.”
A former member of India’s parliament, Bose shared a clip from a speech he delivered to the chamber that year. At the time, students nationwide were demonstrating against caste discrimination. They adopted slogans broadly viewed as in opposition to the government.
“That was the first term of the Modi government,” he recalled. “It was still possible, standing in the Indian parliament, to offer principled opposition.”
For nearly a century, the strongest of India’s universities were funded directly by the central government, Bose explained. “Now it’s the central universities, such as Jawaharlal Nehru University or Hyderabad Central University, which are directly under the thumb of the central government.”
Also impacted are otherstate universities, now controlled by chancellors aligned with Modi’s Hindu nationalist Bharatiya Janata Party (BJP).
“The private universities and other autonomous institutes in the south of India are doing much better,” said Bose, noting a string of states in the region not controlled by the BJP. “These are the spaces for resistance and for standing up for the academic values, which sustain universities.”
Laura V. Jakli, an assistant professor of business administration at the Business School, outlined the recent assault on Hungarian universities. She recalled giving a lecture at Budapest’s Central European University (CEU) in 2017.
“At some point near the end, someone came up to me and whispered that parliament just passed something that might mean this university is no longer operational,” Jakli said. The student body wasted no time in taking to the streets to protest Lex CEU, an educational rule that effectively forced the U.S.–accredited CEU out of Hungary.
Subsequent measures by Prime Minister Viktor Orbán brought schools including the Hungarian Academy of Sciences and the University of Theatre and Film Arts, both in Budapest, under the control of foundations closely aligned with the Orban government.
The “note of hope,” said Jakli, is Hungary’s membership in the European Union. EU leadership has acted to curb these moves, by limiting funds to schools run by quasi-public foundations, for example. It also litigated Lex CEU before the EU’s Court of Justice, which struck down the rule in 2020.
But by then, Jakli submitted, “It was too little too late.” CEU had already relocated its core academic programs to Austria.
Kirby, a historian of modern China, took the conversation back to Asia for a final case study. During its late-Qing and Republican periods, China was home to an “extraordinary group of small universities,” he said. But these institutions were seized or shuttered after Chairman Mao Zedong and his Chinese Communist Party rose to power in 1949.
Kirby rattled off nearly a dozen examples — from Peking Union Medical College, usurped by the Communist Party in 1951, to Tsinghua University, its iconic gate toppled by the Red Army during the Cultural Revolution. The entire system was “Sovietized,” as Kirby put it, or retooled to train workers according to state priorities.
As the event wound down, one attendee raised the lack of hopeful examples. “We haven’t had a story of a successful rebuttal,” agreed Daniel Ziblatt, Eaton Professor of the Science of Government and director of the CES.
In response, Kirby steered the conversation in a surprising direction.
Today, he suggested, China’s research universities are skirting government control to reclaim some of the academic excellence of an earlier era. And institutions like Tsinghua University, in Beijing, have surpassed Princeton and Yale in at least one global ranking.
Tsinghua leaders officially tout “an education with ‘Chinese characteristics’ — whatever the hell that is,’” Kirby noted to laughs. “No one knows what it is. In fact, it’s just to appease the leadership.”
Health
Earlier warning on pediatric cancer recurrence
Mass General Brigham Communications
May 2, 2025
4 min read
AI tool does a better job predicting relapse risk than traditional methods in Harvard study
An AI tool trained to analyze multiple brain scans over time predicted risk of relapse in pediatric cancer patients with far greater accuracy than traditional approaches, according to a new stud
AI tool does a better job predicting relapse risk than traditional methods in Harvard study
An AI tool trained to analyze multiple brain scans over time predicted risk of relapse in pediatric cancer patients with far greater accuracy than traditional approaches, according to a new study. Researchers hope the results lead to improved care for children with brain tumors called gliomas, which are typically treatable but vary in risk of recurrence.
“Many pediatric gliomas are curable with surgery alone, but when relapses occur, they can be devastating,” said corresponding author Benjamin Kann of the Artificial Intelligence in Medicine Program at Mass General Brigham and the Department of Radiation Oncology at Brigham and Women’s Hospital. “It is very difficult to predict who may be at risk of recurrence, so patients undergo frequent follow-up with magnetic resonance imaging for many years, a process that can be stressful and burdensome for children and families. We need better tools to identify early which patients are at the highest risk of recurrence.” Kann is also Assistant Professor of Radiation Oncology at Harvard Medical School.
The results of the study by investigators from Mass General Brigham and collaborators at Boston Children’s Hospital and Dana-Farber/Boston Children’s Cancer and Blood Disorders Center were published in The New England Journal of Medicine AI.
The research, which was funded in part by the National Institutes of Health, leveraged institutional partnerships across the country to collect nearly 4,000 MR scans from 715 pediatric patients. To maximize what AI could “learn” from a patient’s brain scans — and more accurately predict recurrence — the researchers employed a technique called temporal learning, which trains the model to synthesize findings from multiple brain scans taken over the course of several months post-surgery.
“Many pediatric gliomas are curable with surgery alone, but when relapses occur, they can be devastating.”
Benjamin Kann
Typically, AI models for medical imaging are trained to draw conclusions from single scans; with temporal learning, which has not been used previously for medical imaging AI research, images acquired over time inform the algorithm’s prediction of cancer recurrence. To develop the temporal learning model, the researchers first trained the model to sequence a patient’s post-surgery MR scans in chronological order so the model could learn to recognize subtle changes. From there, the researchers fine-tuned the model to correctly associate changes with subsequent cancer recurrence, where appropriate.
Ultimately, the researchers found that the temporal learning model predicted recurrence of either low- or high-grade glioma by one year post-treatment, with an accuracy of 75-89 percent — substantially better than the accuracy associated with predictions based on single images, which they found to be roughly 50 percent (no better than chance). Providing the AI with images from more timepoints post-treatment increased the model’s prediction accuracy, but only four to six images were required before this improvement plateaued.
The researchers caution that further validation across additional settings is necessary prior to clinical application. Ultimately, they hope to launch clinical trials to see if AI-informed risk predictions can result in improvements to care — whether by reducing imaging frequency for the lowest-risk patients or by pre-emptively treating high-risk patients with targeted adjuvant therapies.
“We have shown that AI is capable of effectively analyzing and making predictions from multiple images, not just single scans,” said first author Divyanshu Tak of the AIM Program at Mass General Brigham and the Department of Radiation Oncology at the Brigham. “This technique may be applied in many settings where patients get serial, longitudinal imaging, and we’re excited to see what this project will inspire.”
This study was supported in part by the National Institutes of Health/the National Cancer Institute.
Work & Economy
Funding today, entrepreneurship tomorrow. Or not.
Christina Pazzanese
Harvard Staff Writer
May 2, 2025
5 min read
Threat to research is a threat to U.S. innovation and growth, HBS analyst says
After Harvard rejected Trump administration demands related to hiring, governance, and the viewpoints of faculty and students, the government froze more than $2 billion in grant
Threat to research is a threat to U.S. innovation and growth, HBS analyst says
After Harvard rejected Trump administration demands related to hiring, governance, and the viewpoints of faculty and students, the government froze more than $2 billion in grants for research in science, medicine, and technology at the University. In all, the administration has targeted more than $9 billion in Harvard funding for review. The University responded with a lawsuit late last month.
The disruptive effects of cuts to research funding at Harvard and other institutions of higher ed have already been seen across the U.S. economy. Even if the total funding cuts end up being one-quarter of what has been threatened, gross domestic product will shrink by 3.8 percent (adjusted for inflation) over the coming years, a rate comparable to the 2008-2009 Great Recession, according to new research from economists at American University. Their analysis followed a March report by the nonprofit United for Medical Research that detailed $2.56 in U.S. economic activity for every dollar put into federal biomedical research in 2024.
Less immediately visible are the potential effects the funding freeze could have on a key engine of U.S. economic growth, the startups that help bring scientific innovation and breakthroughs to market.
In this edited conversation, Jeffrey J. Bussgang, senior lecturer in entrepreneurial management at Harvard Business School, discusses the role research universities play in the startup world and how disruptions to funding for science and medicine could reshape the future of entrepreneurship. Bussgang teaches the M.B.A. course “Launching Technology Ventures” and is co-founder and general partner of Flybridge Capital Partners, an early stage venture capital firm.
Jeffrey J. Bussgang.
Photo by Nabil Kapasi
How do research universities figure into the startup and venture capital ecosystem?
There are two critical pathways to bridge the university system and the startup ecosystem. One is through the faculty and the second is through the students.
On the faculty side, often we see commercialization pathways coming out of research in the labs. That can occur both in the computer science departments as well as in the biomedical arenas. And, of course, Harvard has many, many labs and many diverse vehicles, whether it’s the Wyss Institute or the Broad Institute, which operates in conjunction with MIT, as well as the electrical engineering, mechanical engineering, and computer science departments. Robotics, as well. Those tend to be very rich environments for startups.
Second, students benefit from an incredibly rich entrepreneurship curriculum. It’s the most popular field of study at Harvard Business School and the largest faculty unit at Harvard Business School. We consistently have dozens and dozens of startups that come out of our students’ work. As does SEAS — both graduate students and undergraduates.
Research universities seem to play an incubation role in that model. Why has it evolved that way — is it because of risk?
It’s less about risk and more about an intentional curriculum and launching pad for academics and for students. The school is engineered to help faculty through the technology licensing office and various entrepreneurs in residence and venture capitalists that surround the school. We have a very explicit objective of helping our students become company creators and entrepreneurs. So it’s not about risk; it’s more about opportunity and intentionality.
Historically, why is the federal funding of scientific research and development so critical to tech and biomedical startups and entrepreneurs? How does it foster U.S. economic growth?
The more heavily resourced the labs are, the more performative they can be in terms of generating novel ideas that can eventually become massively successful commercial companies. I would also say, the more of a magnet the school is for the best and the brightest internationally, the more likely it is to attract brilliant, aspiring entrepreneurs. And if their work is inspired not by necessarily the labs, but just because of the nature of the work and the quality of the educational system and the quality of the faculty, then that’s also an important magnetic force.
What impact has the federal funding freeze on NIH research and the halting of previously approved grant payments had so far?
We’re just seeing the beginning. There are hiring freezes. There have been initiatives canceled and there have been grants canceled. The pipeline for company creation takes time. The companies that are being created now and launching in 2025 were incubated over the last three years, so we won’t see a short-term effect. It’s going to be more of a medium- and long-term effect in the coming years. We’ll just see fewer promising startups come out of the system.
How long until we start to see the full effects of this situation, and could the damage be reversed?
It could be reversed, but I think it’s going to be a one-to-three-year ripple effect because of how long it takes for these ideas in the lab to come out and to become commercially viable companies.
Maria and Julia Lisella (from left), Josh Kurtz, and Kenny Likis collaborate and reflect on their writing during a workshop in Harvard’s Woodberry Poetry Room. Photos by Grace DuVal
Arts & Culture
Making universal connection through the intensely personal
Anna Lamb
Harvard Staff Writer
May 2, 2025
5 min read
Woodberry Poetry Room workshop project on tradition of elegy inspired by loneliness, g
Maria and Julia Lisella (from left), Josh Kurtz, and Kenny Likis collaborate and reflect on their writing during a workshop in Harvard’s Woodberry Poetry Room.
Making universal connection through the intensely personal
Anna Lamb
Harvard Staff Writer
5 min read
Woodberry Poetry Room workshop project on tradition of elegy inspired by loneliness, grief of pandemic
Elegy, a form of poetry traditionally meant to honor the dead and lament the loss, is often composed in solitude. On a warm recent Tuesday afternoon in Lamont Library, a small group — some poets, most not — gathered to write, read, and workshop elegies of their own.
The workshop, led by Karen Elizabeth Bishop and David Sherman in partnership with the Woodberry Poetry Room, is part of the duo’s ongoing “Elegy Project.” The event late last month was paired with a reading that evening in Houghton Library’s Edison Newman Room by poet Peter Gizzi, author of the T.S. Eliot Prize-winning collection “Fierce Elegy.”
“The Elegy Project is a public poetry initiative,” Sherman said. “We put poem cards in public places for strangers … Our intention is to make grief less lonely.”
Poet Peter Gizzi reads in a companion event.
The Elegy Project was the recipient of the Poetry Room’s 2023 Community Megaphone grant. Using funds provided by poet Tom Healy ’83, the Poetry Room began offering stipends to individuals and nonprofits in the Boston area to support their work and creative contributions to the community.
“Elegy is perhaps the most primal and human of poetic impulses — the need to mourn, to praise, and to console all springing from the inescapable human predicament: to be alive is to experience loss,” said Mary Walker Graham, associate curator of the Woodberry Poetry Room. “Elegy not only makes this loss more bearable, it enlarges our capacity to experience the full spectrum of human emotion.”
Started in spring of 2022, Bishop and Sherman said they were inspired to create the Elegy Project when they noticed the loneliness and grief caused by the pandemic and thought there must be a way to show people that they weren’t alone.
“During the pandemic we wanted to do an anthology of elegy. But the publishing world works at glacial speed,” Bishop said. “Everybody was in their houses. And so we thought to do a deconstructed anthology that would be immediately free and accessible, and ‘aggressively randomly accessible,’ as Dave says.”
Both Bishop and Sherman distribute poetry cards wherever they go.
“I walk around with thumbtacks in my pocket and the cards, and I put them on wooden utility poles, or leave them in the post office, on the train, or the bus, or maybe a bench, and it’s aggressively contingent and random,” Sherman said. “It’s unsystematic. It’s aggressively embracing randomness.”
Both Bishop and Sherman say they use elegy in their professional work as well. Bishop is an associate professor of Spanish and Comparative Literature at Rutgers University, where she researches and teaches modern poetry and narrative. Sherman is an associate professor of English at Brandeis University, where he researches elegy and the politics of commemoration.
“I think that elegy performs this beautiful kind of stretching toward something that’s gone or something that’s gone missing,” Bishop said. “Isn’t that the nature of death? That you want to reach out, you want to kind of make that movement forward.”
Kenny Likis (center) and other participants use the Poetry Room’s collection and prompts by workshop leaders for inspiration.
Xiaolong Yang (left), a student at the Griffin Graduate School of Arts and Sciences, compares notes with poet Hajjar Baban.
“Our intention is to make grief less lonely,” said Elegy Project co-founder David Sherman (right).
This most recent workshop was the second between the Elegy Project and the Poetry Room. Last spring they did poetry workshops with invited guests. This time around, there was an open call for anyone interested in crafting a poem.
“I think these are people who probably use poetry privately and maybe share with a few friends, and want to expand that experience by a significant step,” Sherman said. “These were people who are busy with life, busy with real experiences where poetry is useful for processing, and they just want to write in community.”
The group assembled ranged from doctoral candidates in physics to retired painters. They were asked to use the Poetry Room’s collection and prompts by Sherman and Bishop for inspiration.
“Elegy is perhaps the most primal and human of poetic impulses — the need to mourn, to praise, and to console all springing from the inescapable human predicament: to be alive is to experience loss.”
Mary Walker Graham
“The thought behind the steps was to create a dynamic conversation between people and books, between people and people, between lines and other lines, so that something unexpected would emerge,” Sherman said. “It was exploring openly, exploring new books on the shelves, and then feeling the desire to say something back of your own.”
Bishop added that using prompts and exploring texts can help get the creative juices flowing, too.
“It takes a little bit of the pressure off sitting around waiting for a line to appear or waiting for your brain to come up with something,” she said. “I think that that kind of scaffolding is really useful for people to get into to writing a poem or just engage poetry in some way.”
Graham, the Poetry Room’s associate curator and co-organizer of the event, said workshops like the Elegy Project’s are important to engage the community and bring poetry out from the stacks.
“Poetry belongs to everyone, not just to the authors of published books,” she said. “We all have an equal right to access it, not only to receive it but to create it. Workshops like this one nurture the poets in us all.”
Nation & World
How hot is too hot?
A worker labors in the heat of Uttar Pradesh, India, hauling bricks from a kiln.Photos by David Trilling
David Trilling
Salata Institute Communications
May 2, 2025
8 min read
Teaming up with grassroots organizers in India, Harvard researchers are collecting data to help workers adapt to dangerous spikes in heat
When it gets hot in Ahmedabad, bats pa
A worker labors in the heat of Uttar Pradesh, India, hauling bricks from a kiln.
Photos by David Trilling
David Trilling
Salata Institute Communications
8 min read
Teaming up with grassroots organizers in India, Harvard researchers are collecting data to help workers adapt to dangerous spikes in heat
When it gets hot in Ahmedabad, bats pass out and fall from the trees.
Climate change is forcing temperatures into the upper limits of what many mammals, including humans, can bear. Heatwaves are more frequent and last longer. People in the world’s hottest places — like Ahmedabad, a 15th-century city of about 8 million in western India — now routinely struggle for months at a time. Air conditioning there is rare.
While extreme daytime temperatures grab headlines, “being indoors, at home, during the rest hours can be just as dangerous and deadly,” said Satchit Balsari, associate professor in emergency medicine at Harvard Medical School.
Adapting to this new reality is a matter of life or death. But to test adaptation strategies — say, how much does a white roof cool the room below? — urban planners need basic data. For example, how hot is it really in the places where people live and work? Ahmedabad’s official temperature is measured at an airport weather station standing out in the open, not in the dense urban microclimates where homes and livelihoods are concentrated. And how does the body respond to prolonged high temperatures? Or, as Balsari put it: “How do you define how hot is too hot?”
Harvard researchers are working with community leaders in India to build one of the largest datasets ever recorded on extreme heat and human well-being.
Cities and states across India are developing heat action plans to mitigate the impacts on their populations, though they often overlook informal workers.
The data will let civil society groups lobby on behalf of policy solutions, because there are no precise statistics in India on how heat affects work.
To answer these questions, Harvard researchers are collaborating with community leaders in Ahmedabad to build one of the largest datasets ever recorded on extreme heat and human well-being — data that could help millions of others facing rising temperatures around the world. The research team is placing thumb-size heat and humidity sensors in the workplaces and homes of hundreds of local women — in urban dwellings, on streets, and on farms — and monitoring their health with Fitbits and regular checkups over a year.
“This study was born out of an attempt to quantify the lived experience, the temperatures people are experiencing day after day in their homes, and what that means for their health, their heart rate, kidney function, their sleep,” said Caroline Buckee, professor of epidemiology at Harvard T.H. Chan School of Public Health.
Policies meant to offset extreme heat often focus on the risk of heat stroke, “but there’s a range of other health impacts that injure and kill people more slowly,” she added.
A woman harvests wheat at twilight, after the worst of the afternoon heat, in Uttar Pradesh.
A man erects shade to protect worshippers ahead of Friday prayers at a mosque in Delhi.
Balsari and Buckee lead a research cluster — funded by the Salata Institute for Climate and Sustainability and supported by the Lakshmi Mittal and Family South Asia Institute — studying the impact of warming microenvironments on the lives and livelihoods of the Indian working poor.
“During our pilot study, in certain homes we found temperatures up to 10 degrees hotter than the airport weather station data,” said Balsari. “We realized that a lot of global modeling efforts were dependent on data at a temporal and spatial resolution that may not reflect the lived reality of the millions of people most at risk in South Asia.”
Inside one home their team recorded a heat index of 137 degrees Fahrenheit — a measure that combines temperature and humidity to reflect how hot it feels. “That’s extreme, but the fact that the numbers cross 120 F routinely is terrifying. These thresholds, in many contexts, are unlivable,” Balsari said.
Building resilience with data
Study participants are tenant farmers and piece-rate workers. Data collectors are local social workers who visit participants every two weeks in their homes and workplaces to download data onto a customized smartphone app.
Cities and states across India are developing heat action plans to mitigate the impacts on their populations, though they often overlook informal workers.
The data will let civil society groups lobby on behalf of durable policy solutions, like heat action plans that take their members into account, because there are no precise statistics in India on how heat affects work.
Already these groups offer a growing menu of novel responses to heat: affordable finance to paint roofs a heat-reflecting white, buy umbrellas to shade market stalls, and install vents that let heat escape concrete-block homes. Another innovation is parametric heat insurance: Members buy a policy that will pay a day’s wage when the temperature exceeds a preset threshold, to allow them to stay home during the most brutal heatwaves and not have to choose between feeding their families and protecting their health.
Air conditioning is rare in the 15th-century city of Ahmedabad.
These insurance policies are designed to cover the kind of losses suffered last year by Ramila, who sells okra and tomatoes, bottle gourds, and fresh fenugreek from a cart she has pushed around Ahmedabad for 28 years.
Summers have gotten hotter and longer, she said, especially in the last few years. “But I still have to run my business.”
Last May, on one of the many days the mercury topped 110 F, Ramila, 47, passed out and hit her head on the ground. A bystander called an ambulance, which took her to a hospital. “That day my vegetables spoiled, so that was a loss. Plus, I incurred hospital costs — a double loss,” she recalled.
This year 250,000 women bought a policy ahead of the heat season, which peaks in May.
No escape
After a deadly 2010 heatwave, Ahmedabad adopted a heat action plan, the first in South Asia. It encourages public awareness of the dangers, trains doctors to spot heat stroke, and expands supplies of drinking water.
Still, argued one of its authors, Dileep Mavalankar of the Indian Institute of Public Health, “there is gross underreporting of heatwave-related deaths” across India, which might be recorded as heart attacks or other emergencies. “The combination of very high daytime temperature and warm nights kills the most. It is so hot that bats are falling unconscious and dropping out of the trees.”
Researchers are placing heat and humidity sensors in the workplaces and homes of hundreds of local women and monitoring their health with Fitbits and regular checkups.
Data collectors visit participants every two weeks to download data onto a smartphone app.
Initial data from the project is validating concerns about the home environments, which remain hot and humid well into monsoon season.
Initial data from the project — known as “Community Heat Adaptation and Treatment Strategies” — is validating concerns about the home environments, which remain hot and humid well into monsoon season.
“The way homes are designed, they absorb and store a lot of heat,” said Robert Meade, a postdoctoral research fellow with the Salata cluster. “Imagine a street vendor. They go to work in the hottest period of the day. Then they return to overheated homes where they must recover, take care of family, clean — all in an environment that is actually hotter than outdoors and doesn’t get that same nighttime drop in temperatures measured out at the airport weather station.”
An adaptation model
Down a lane wide enough only for pedestrians and mopeds, Karunisha, 55, works as a seamstress in her one-room home in Ahmedabad.
On the cornflower-blue wall, a white sensor records the humidity and temperature, 24 hours per day, year-round. A thermometer reads 93 F on a March afternoon.
“My neighbors gossip. They say the sensor is a camera, that I am being spied upon. But I know the data is being collected to help us,” says Karunisha, describing how it “gets hotter every year, so hot I get too weak to work.”
Without local trust in civil society, the Harvard researchers would not be able to reach so many vulnerable women in India’s poorest neighborhoods, said Buckee, the principal investigator.
“It is extremely difficult to implement this kind of study. You have hundreds of participants, sensors that need to be checked, private data. You have to do lab tests regularly. This level of coordination is simply not possible in most places. It’s possible here because our partners are doing the work and they care about finding the answers,” said Buckee.
The research cluster is now scaling up — expanding to other parts of India, distributing Fitbits and sensors in time for peak heat this year. As they collect empirical observations to inform a ground-up picture of the health risks from climate change, they are pioneering a new type of adaptation model by and for workers.
“We see this as a research platform that our partners themselves can use to test their own adaptations, to decide which work best for them,” Buckee said.
Kira Pollack.Photograph by Peter Hapak
Arts & Culture
Could the same tech that is threatening photojournalism offer a way to save it?
Shorenstein fellow wants to deploy AI to preserve the visual record. An image from the front lines in Iraq provides a test.
Sy Boles
Harvard Staff Writer
May 1, 2025
7 min read
Artificial intelligence poses a serious threat to photography and to photojo
Could the same tech that is threatening photojournalism offer a way to save it?
Shorenstein fellow wants to deploy AI to preserve the visual record. An image from the front lines in Iraq provides a test.
Sy Boles
Harvard Staff Writer
7 min read
Artificial intelligence poses a serious threat to photography and to photojournalism, whether through copyright violations or through synthetic images blurring trust in what’s real. But Emmy award-winning visual storyteller Kira Pollack says the same technology that is threatening photojournalism might also offer a way to save it.
Pollack, who has shaped the visual identity of major brands including TimeMagazine, Vanity Fair, and The New York Times Magazine, is now the Walter Shorenstein Media & Democracy Fellow at the Shorenstein Center on Media, Politics and Public Policy. She is researching ways to use AI to protect the vast archives of professional photojournalists as a record of the world as it really was, and she’s using the archive of war photographer.
She spoke with the Gazette in this edited conversation.
You were the creative director at Vanity Fair as AI first entered the mainstream. What were your initial thoughts about AI’s potential to impact photography as a craft and an industry?
My immediate reaction was that we were entering an entirely new era of image-making — one that posed an existential threat to photography as we know it. On one hand, the sophistication of fabricated images was terrifying; on the other, it promised an explosion of creativity. At Vanity Fair, I was commissioning highly produced fashion images of public figures and gritty journalistic pictures from the front lines. As generative AI tools and large language models began to rapidly evolve, and fake images started circulating widely, alarm bells were sounding across the photojournalism community. In my experience, every time a new technology disrupts photography, the most important thing is to understand it — learn how it works, how it might be harnessed for good, and how to protect against its potential harms.
Your fellowship at the Shorenstein Center is focused on addressing a very specific challenge for photojournalists, so tell me about the problem you identified.
One of the greatest challenges facing photojournalism today is the fate of its archives. When people hear the word “archive,” they often picture dusty boxes — and their eyes glaze over. But to me, archives are living, breathing bodies of work that tell the visual history of our world. Having been on the front lines of assigning that work — as director of photography at Time, deputy photo editor at The New York Times Magazine, and most recently at Vanity Fair — I know the extraordinary material these archives contain. Over the course of their careers, photojournalists amass hundreds of thousands of images, and I’d estimate that 95 percent have never been seen or published. A finite number of professionals documented the defining events of our time, and their images are often the only visual record we have. Many of the world’s greatest photojournalists are still alive and able to contextualize their life’s work — yet we’re at real risk of losing it.
At a moment when we urgently need to preserve these photographs before the era of AI further distorts our sense of visual truth, we also need to explore how AI itself might help. Can these tools help us catalog, organize, and contextualize this vital work to make it discoverable? Can we do it ethically, without exposing these images to unauthorized training or misuse? What are AI’s shortcomings? That’s the core of my research: how to use AI to help us see — at scale — without compromising the integrity of what we see.
“I want to understand where this technology is headed, where it falls short, and whether it can serve the core values of photography: truth, authorship, and memory.”
How have you started experimenting with this so far?
Working with photojournalist Christopher Morris and engineer Gregor Hochmuth, we’ve conducted nearly a dozen case studies using images from Morris’ archive. In one study, we selected a range of stories — including the U.S. invasion of Iraq, Jan. 6, and the Yugoslav wars — and asked AI to evaluate the images. While AI can easily identify simple visuals — a cat, a car, a person — the real test is whether it can interpret the layered complexity of conflict photography. In one striking example, the AI analyzed a photo from the U.S. invasion of Iraq and correctly identified the action as a house raid, the setting as a residential building, the make of the soldiers’ guns, and the emotions on the civilians’ faces — using nuanced language like “appears nervous” or “appears apprehensive.” It even assessed the composition, lighting, and symbolism. We were stunned that it could extract such specific and accurate insights with so little context.
Artificial intelligence offered a comprehensive analysis and helpful cataloging notes of Christopher Morris’ photo, which showed the 3rd Infantry Division in Baghdad, Iraq, on April 6, 2003.
Credit: Christopher Morris / VII
We’re also exploring questions of authorship and legacy. Archives should be more immersive and dynamic — there’s a depth of narrative and intent from the photographer that goes far beyond captions or keywords. We’re experimenting with how AI might help bring that storytelling to the surface.
You see a potential for AI to help photographers preserve their vast archives of work. How do you square that use of AI with this other side of the conversation, where there are real concerns about the erosion of trust in what’s real?
I see these as two distinct conversations with some overlap — like a Venn diagram. One part of the conversation focuses on generative AI’s ability to create photorealistic images without a camera or lens. In today’s relentless breaking news environment, where images spread rapidly on social media without gatekeepers, this can be a dangerous mix that erodes public trust. Another concern is copyright — specifically, the risk of photographers’ work being scraped and used to train AI models without consent. This raises urgent questions about ownership, authorship, and protection.
The work I’m doing exists in a third circle of that Venn diagram. It’s about using AI not to generate or exploit images, but to preserve, organize, and surface real photojournalism. These archives are vast, often inaccessible, and under threat — both physically and digitally. I’m exploring whether AI can help responsibly unlock this material at scale, while safeguarding the photographer’s intent, rights, and legacy. It’s about using the technology to reinforce visual truth — not replace it.
What are your hopes for the Shorenstein Fellowship?
My hope is to use this time not just to examine the technology itself, but to engage deeply with the larger questions it raises for photography and journalism. What makes the Shorenstein Center so unique is the opportunity to be in dialogue with people across disciplines — technologists, ethicists, journalists, policymakers — who are thinking critically about the future and the values we carry forward.
I’m not coming to this work as a technologist. I come from journalism, having worked closely with photojournalists around the world and led teams that helped shape how the public sees history as it unfolds. Rather than getting swept up in the momentum of the tech world, I want to understand where this technology is headed, where it falls short, and whether it can serve the core values of photography: truth, authorship, and memory. Ultimately, I hope to bring these insights back to the photojournalism community — to help ensure we’re not just reacting to change but helping to shape it.
Health
Worth the grind
Karen Emmons studies strategies to reduce cancer risk and Jorge Chavarro conducts research on nutrition and human reproduction.Photos by Veasey Conway/Harvard Staff Photographer and via AP; photo illustration by Liz Zonarich/Harvard Staff
Sy Boles
Harvard Staff Writer
May 1, 2025
5 min read
Hard work of securing a federal grant pays off for researchers: ‘It means you can do
Karen Emmons studies strategies to reduce cancer risk and Jorge Chavarro conducts research on nutrition and human reproduction.
Photos by Veasey Conway/Harvard Staff Photographer and via AP; photo illustration by Liz Zonarich/Harvard Staff
Sy Boles
Harvard Staff Writer
5 min read
Hard work of securing a federal grant pays off for researchers: ‘It means you can do something to try to help people.’
For public health researchers, getting a federal grant is a big deal.
More than 30 years later, Karen Emmons hasn’t forgotten her first one. She was an assistant professor in Brown University’s Department of Psychiatry when the letter came in the mail on green carbon-copy paper that was so smudged she could barely read it. Now a professor of social and behavioral sciences at the Harvard T.H. Chan School of Public Health, she still has that faded piece of green paper.
“You go into science because you want to make a difference, and when you get a grant, it means you can do something to try to help people,” Emmons said. “It just has so much meaning.”
Those meaningful moments are now under threat. The Trump administration has frozen more than $2.2 billion in research grants to Harvard, halting studies with implications for neurogenerative disease, tuberculosis, and other conditions. The government’s move came after Harvard rejected White House demands for viewpoint “audits” of students and faculty, hiring changes, and other measures. Last week, the University filed suit against the administration.
The halt to funding disrupts a process that researchers say is appropriately competitive considering the stakes of their primary goal: advances in science and human health.
Jorge Chavarro, a professor of nutrition and epidemiology at the Chan School, understands the challenges from both sides. He applies for grants for his research on nutrition and human reproduction, and he’s served for about a decade on a scientific review group, also called a study section, evaluating other investigators’ proposals.
“The NIH really does everything it can to ensure there is an absolutely fair review process for every single application,” he said.
“You can’t just say, ‘I have this idea, please give me grant money.’”
For Emmons, who studies strategies to reduce cancer risk in under-resourced communities, the work begins long before the application is written. It includes building relationships with community partners, staying up to date on what’s been published in her field, and networking with other researchers to gain a sense of what’s coming next.
“You don’t want to do things that somebody’s already doing,” she said. “You want to take things in a new direction.”
Then you have to test the idea. The NIH requires evidence that the research is not just innovative but grounded in evidence.
“You can’t just say, ‘I have this idea, please give me grant money,’” Emmons said.
It could take another six months to write the application, which begins with a one-page statement, known in NIH lingo as specific aims, explaining how the study fills existing gaps, the impact it could have, and the methods investigators will use. After the aims page comes the full application, which can stretch to more than 100 pages once you add in the 12 pages of detailed science and all the required administrative documentation, Chavarro said. It includes dense summaries of previous work, results from preliminary research, detailed descriptions of methodology, and a biosketch, a kind of academic CV. For Emmons, who works with human participants, there are also lengthy requirements for ensuring the ethical treatment of her subjects. And of course, there’s the budget.
The cost of doing innovative research has grown faster than the average size of a typical grant, Chavarro said, effectively requiring scientists to be more innovative with the same amount of money. So every line in the budget must be justified. “Why is it important to buy a new piece of equipment that you don’t have?” he said. “Why do you need money for tubes or pipettes, liquid nitrogen?”
Once submitted, applications are assigned to Scientific Review Groups made up of volunteer scientists who can judge the research on its merits. Study sections score proposals against one another for their innovation, significance, and approach. Then, advisory councils for each institute perform a second-level review to determine whether the studies fit with the missions of their organizations. The two reviews are aligned, and only the top projects receive funding.
Success varies by institute, but at the National Cancer Institute, where Emmons submits most of her applications, there was a 14.6 percent success rate for the most common type of grant, the R01, in 2023, the most recent data available. That means for all the months or years of preparation, the pilot studies, the partnership-building, the haggling over budget lines, only one in six proposals will be funded. Researchers whose proposals aren’t funded have a chance to incorporate feedback and resubmit.
Both Chavarro and Emmons accept that the process can be frustratingly slow. The meticulousness of the approach, they say, is part of what makes it exceptional. Emmons pointed to the decadeslong public-private partnership between universities and the government as a shared commitment to science as a public good.
“Early on, the government realized it benefits society and it benefits the government: It keeps people healthier, it gives people access to lifesaving treatments, and it reduces the cost of taking care of people when they’re ill,” she said. “It’s just what the government should be doing: It should be helping people.”
Work & Economy
Rick Scott argues tariffs will level playing field, help U.S. workers
Jason Furman (left) and Sen. Rick Scott at the JFK Jr. Forum.Niles Singer/Harvard Staff Photographer
Liz Mineo
Harvard Staff Writer
May 1, 2025
3 min read
Republican senator also views China as nation’s most concerning competitor
Republican Senator Rick Scott defended the Trump administration’s tarif
Rick Scott argues tariffs will level playing field, help U.S. workers
Jason Furman (left) and Sen. Rick Scott at the JFK Jr. Forum.
Niles Singer/Harvard Staff Photographer
Liz Mineo
Harvard Staff Writer
3 min read
Republican senator also views China as nation’s most concerning competitor
Republican Senator Rick Scott defended the Trump administration’s tariff strategy as a way to press other nations to drop their own levies on American products during a recent conversation with Jason Furman, Aetna Professor of the Practice of Economic Policy.
“What [President] Trump is saying is that the American worker is not going to be disadvantaged any longer,” said Scott. “My approach would be I want the American worker to sell more stuff. So, lower your tariffs, lower your barriers, get rid of all of it.”
The government announced a sweeping series of tariffs on most of the nations in the world in early April as part of an attempt to reshape decades of U.S. trade policy. The move has triggered volatility in global stock markets and is being blamed, in part, for a sharp contraction in first quarter gross domestic product.
At the April 13 event hosted by the JFK Jr. Forum at the Institute of Politics, Furman asked Scott whether he thought the White House could have pursued negotiations with trading partners instead of imposing tariffs unilaterally. It could have prevented fears of an economic downturn that wiped $6 trillion off the stock market, said Furman.
Scott said American workers ultimately will benefit from Trump’s tariffs.
“I want American workers to sell their stuff. Don’t put any barrier on us, we won’t put any barriers on your country’s workers … I don’t know if it’s better to do a big deal like that or individual deals, but I would make it as simple as that,” said Scott, a longtime Trump ally who was governor of Florida from 2011 to 2019.
“My belief is that we should do no trade with China. The only way we don’t go to war with China is if their economy is demolished.”
Sen. Rick Scott
Trump has said tariffs could help close trade deficits and help U.S. manufacturers and workers, but many economists disagree. In a New York Times column, Furman said that Trump’s tariffs would hurt the U.S. economy.
The conversation touched on a wide range of topics, from tariffs to China to debt and executive power. Scott saved his most pointed criticism for China, a country whose economic and political power is more concerning to him than that of Russia.
“My belief is that we should do no trade with China,” said Scott. “The only way we don’t go to war with China is if their economy is demolished.”
The government levied a 10 percent tariff rate on most nations with the exception of China, which now faces a rate of 145 percent. In retaliation, China imposed a 125 percent tariff on U.S. imports.
When asked about the national debt, which the nonpartisan Congressional Budget Office projects will be about $20 trillion over the next decade, Scott suggested that a balanced budget and reduced spending are necessary to help improve the nation’s fiscal outlook.
As for his view on whether tariffs will lead to inflation, Scott said he is not sure.
“I don’t know what the tariffs will do to inflation,” he said. “I think inflation will only get under control if we balance the budget. We’ll see what the tariffs do.”
Health
‘Devastating’ global health void, Gawande says
Surgeon-author speaks from his experience as a leader at USAID before it was gutted
Christina Pazzanese
Harvard Staff Writer
April 30, 2025
4 min read
Atul Gawande with Marcia Castro.Niles Singer/Harvard Staff Photographer
Surgeon and best-selling author Atul Gawande on Monday provided a close-up account of the damage inflicted by the
Surgeon-author speaks from his experience as a leader at USAID before it was gutted
Christina Pazzanese
Harvard Staff Writer
4 min read
Atul Gawande with Marcia Castro.
Niles Singer/Harvard Staff Photographer
Surgeon and best-selling author Atul Gawande on Monday provided a close-up account of the damage inflicted by the Trump administration’s dismantling of the U.S. Agency for International Development, but with a note of encouragement to students and faculty to stay committed to science and medicine.
Gawande, a surgeon at Brigham and Women’s Hospital and faculty member at the Harvard T.H. Chan School of Public Health and the Medical School, took leave from the University in 2021 after President Joe Biden nominated him to head USAID’s Bureau for Global Health, a post he called “the best job in medicine that you’ve likely never heard of.” He stepped down at the end of Biden’s term.
“USAID cannot be restored to what it was, but it is not too late to save our health and science infrastructure and our talent.”
Atul Gawande
The firing of nearly all USAID staff and the termination of more than 85 percent of its programs have caused “devastating” damage to millions of people and to the U.S. as a global health leader, he said.
“What I know now, three months from when I departed my role at USAID, is USAID cannot be restored to what it was, but it is not too late to save our health and science infrastructure and our talent,” he said during a conversation with Marcia de Castro, Andelot Professor of Demography at the Chan School. “And it’s not too late to stop the destruction.”
Referencing recent government actions halting Harvard research funding, he added: “I’ve returned to this community as it’s come under attack.”
Under threat, he noted, are federal programs supporting health and science, including at the National Institutes of Health and Centers for Disease Control, and partnerships with universities and medical centers. The funding freeze has hit Ariadne Labs, a Harvard- and Brigham and Women’s-affiliated research center Gawande founded in 2012, endangering research and testing related to surgery, childbirth, and primary care, he said.
Recalling his time with USAID, Gawande said that the agency, working with half the budget of a typical Boston hospital, built a 50-country network to surveil deadly diseases like Ebola and bird flu faster than ever before, cutting emergency response time to global outbreaks from more than two weeks to less than 48 hours. Programs to prevent maternal and childhood deaths, which reached 93 million women and children under 5, added six years to their life spans, he said, while support for programs to prevent and treat HIV, tuberculosis, and malaria dramatically improved outcomes for tens of millions of people. Before he stepped down, USAID was preparing to scale up a novel and inexpensive treatment package to reduce severe hemorrhaging after childbirth, the leading cause of maternal deaths.
Most countries USAID was assisting still have six- to nine-month stocks of medications; it’s the immediate cuts to staffing and services that will now affect health outcomes most acutely, said Gawande, who is this year’s Harvard Alumni Day speaker.
“It’s not just having a solution; it’s the follow-through,” he said. “So much of the power of what USAID does, that I see [the World Health Organization] doing as well, is the technical assistance that gets you from 60 percent vaccination to 80 percent and then to 90 percent vaccination.”
Gawande, who in addition to his work in a medicine is a New Yorker staff writer and the author of several books, maintained that he’s “hopeful” about global health in the long run. Still, he said, “As an American, one of the things I’m quite uncertain about is whether America is going to be part of leading and part of the solution any time soon.”
But if the U.S. is no longer going to take a leading role in global health, he said, other countries and individuals will almost certainly emerge to take the reins — along with leaders in Massachusetts and other states.
Whatever happens in the near term, the work of global health remains vital, he told students.
“You and your expertise will be needed no matter what,” he said.
To view a video of the talk, visit the Harvard Chan School YouTube site.
Health
More proof that money isn’t everything
“It raises important questions with regard to whether we are investing enough in our youth,” said Tyler VanderWeele about findings from a new study he led on global well-being.File photo by Niles Singer/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
April 30, 2025
6 min read
Major global study of flourishing ranks wealthy, lower-income na
“It raises important questions with regard to whether we are investing enough in our youth,” said Tyler VanderWeele about findings from a new study he led on global well-being.
File photo by Niles Singer/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
6 min read
Major global study of flourishing ranks wealthy, lower-income nations, reinforces concerns over well-being among youth
A major global study of human flourishing reinforces prior warnings about the lack of well-being among youth, particularly in the U.S., and highlights the adage that money isn’t everything, with middle-income — not wealthy — countries topping a ranking of 22 nations.
“It raises important questions with regard to whether we are investing enough in our youth,” said Tyler VanderWeele, the John L. Loeb and Frances Lehman Loeb Professor of Epidemiology at the Harvard T.H. Chan School of Public Health and one of the study’s lead authors. “Patterns around the world are complex, but in many countries — especially Western countries — this pattern is real.”
The results stem from a huge trove of data gathered by The Global Flourishing Study, a major investigation into individual well-being within specific communities and environments. The survey enrolled about 203,000 people speaking 40 languages and spanning an array of nations, cultures, histories, and economic circumstances. Launched in 2021, the study was conducted on all six inhabited continents and represents about 64 percent of the world’s population, organizers said during a media briefing Monday.
The study’s data allow for comparison across and within nations. Respondents were asked questions about seven variables that together define “flourishing” — health, happiness, meaning, character, relationships, financial security, and spiritual well-being.
It also gathered demographic data such as age, sex, marital and employment status, education, health, religious service attendance, and information about personal history, specifically childhood, including family financial circumstances and exposure to abuse.
VanderWeele called the findings on youth flourishing “troubling.” He said they bear out other recent findings that point to change.
Formerly, a typical life pattern of flourishing looked like a U-shaped curve, with satisfaction highest early and late in life. The lowest point came during the middle years when the pressures of raising children, meeting work expectations, and caring for aging parents come to bear.
It has now shifted to something like a J-shape, with measures of flourishing turning nearly flat from the late teens into the 20s before rising later in life. That pattern was seen in several nations, VanderWeele said, but the U.S. had one of the steepest gradients between flourishing levels of its youth and older adults.
The study, published in the journal Nature Mental Health and sponsored by eight private foundations, was led by researchers at Harvard and Baylor universities and included colleagues from 21 institutions, including universities in the U.S., Germany, Poland, Spain, Canada, and the U.K., as well as the Gallup polling firm.
VanderWeele said the national ranking data was the study’s biggest surprise, offering strong evidence that financial circumstances alone don’t guarantee flourishing. The study surveyed 22 countries and one territory (Hong Kong) that organizers said span an array of cultures, races, economic circumstances, and living conditions.
A ranking without financial indicators put Indonesia at the top, followed by Mexico, the Philippines, Israel, and Nigeria. The U.S. was 15th on that list. Adding financial indicators reordered the list slightly, with Israel and Mexico switching places, and Poland moving into the top 5, bumping Nigeria down. The U.S. moved up to 12th in that ranking. Last on both lists, however, was Japan.
Brendan Case, associate director for research at the Human Flourishing Program and a paper author, said the national rankings call into question prevailing models of economic development that raise as examples nations such as Japan — whose rapid post-World War II modernization made it a global industrial power. That contrasts with Indonesia, a nation often cited as an example of the “middle-income trap” where developing nations’ initial economic progress turns to long-term stagnation.
While Japan is wealthier and its people live longer, respondents there were the least likely to answer “yes” to a question asking whether they had an intimate friend, Case said. Indonesia, meanwhile, ranked higher in measures of relationships and pro-social character traits, which foster social connections and community.
“We’re not here to say those outcomes [wealth, longer lifespans] don’t matter a lot, or that we shouldn’t care about democracy, we shouldn’t care about economic growth, we shouldn’t care about public health,” Case said, “but it’s interesting to consider that the Global Flourishing Study raises some important questions about the potential tradeoffs involved in that process.”
While many of the survey’s broader trends masked significant variability, there were a few findings that were nearly universal. Having good maternal and paternal relationships as a child and excellent childhood health were universally associated with higher adult flourishing.
Weekly or more frequent attendance at religious services also was nearly universally associated with adult flourishing. Authors said the salutary effect of religious participation tracks with previous studies in the West and now has been documented globally.
“The results also raise important questions for the future progress of society,” the authors wrote. “Are we sufficiently investing in the future given the notable flourishing-age gradient with the youngest groups often faring the most poorly? Can we carry out economic development in ways that do not compromise meaning and purpose and relationships and character, given that many economically developed nations are not faring as well on these measures? With economic development and secularization, have we sometimes been neglecting, or even suppressing, powerful spiritual pathways to flourishing?”
Researchers said the dataset is enormous — it’s the result of what are essentially 23 separate national or territorial longitudinal studies — and contains many interesting patterns, more of which will emerge with additional analysis. It also extends globally the investigation into human flourishing, which has been mainly focused on populations in the West.
“Each country is a unique place, and we’re keen to study and understand that,” said Tim Lomas, a research scientist in epidemiology at the Harvard Chan School and at the Human Flourishing Program and a paper author.
Some of the questions raised by the survey may be answered as additional data is collected, Case said. The study, which resulted from a Harvard conference six years ago, is longitudinal, so researchers will resurvey respondents annually, with additional analyses planned to be released over the next five years.
“If society is to ultimately flourish,” the authors wrote, “these questions of age, and of development, and of spiritual dynamics need to be taken into consideration.”
Photo by Michael Goderre/Boston Children’s Hospital
Health
Protecting the brain requires persistence
Beth Stevens, NIH-supported investigator of Alzheimer’s and other disorders, explains how one discovery can lead to another
Sy Boles
Harvard Staff Writer
April 30, 2025
3 min read
Part of the
Profiles of Progress
series
In efforts to fight Alz
In efforts to fight Alzheimer’s disease, neuroscientist Beth Stevens has driven a transformation in thinking about microglial cells, which serve as an immune system for the brain.
Microglia patrol the brain for signs of illness or injury, helping clear out dead or damaged cells and selectively pruning synapses, which transmit information among neurons. Sometimes the process takes a dangerous wrong turn.
The Stevens Lab, based at Boston Children’s Hospital and the Broad Institute of MIT and Harvard, has demonstrated that aberrant pruning can contribute to Alzheimer’s disease, Huntington’s disease, and other disorders.
The work has created a foundation for new biomarkers and medicines to detect and treat neurodegenerative disease. It has the potential to affect care for the estimated 7 million Americans living with Alzheimer’s, which is incurable.
“We would never have been able to move forward without the basic science and curiosity-driven science from the beginning.”
When she was starting out, in the early 2000s, Stevens, now an associate professor of neurology at Harvard Medical School, had no idea where her curiosity would take her.
“I was just following the science,” she said. “It was this interesting new area where the brain’s immune system was helping to sculpt synapses and circuits under normal development.”
She had a hunch about synaptic pruning — and she was right. Vital support from federal agencies helped her follow through.
“The foundation of our research, from the time I was a postdoc to the first decade of my lab, was almost entirely driven by the National Institutes of Health and other federal funding,” she said.
That foundational research doesn’t always have a clear outcome, noted Stevens, who was named a MacArthur “genius” for her work on microglia in 2015. “Someone that doesn’t think about disease implications might say, ‘Oh, Stevens Lab is studying the visual system of a mouse. They’re trying to understand how a mouse’s visual system wires up.’ It can seem like that’s so far from ever translating into anything. Who cares how a mouse might see?”
But these studies allow scientists to explore questions they couldn’t in humans, she noted — which leads to new discoveries, which lead to new understandings of disease, which lead to treatments that improve human lives.
“Our microglial research,” Stevens said, “is a great example of an immune-related pathway and cell type that we would never have been able to move forward without the basic science and curiosity-driven science from the beginning.”
Campus & Community
Four awarded Harvard Medal for exceptional service
A veritas shield hangs above the entrance to Memorial Church in Harvard Yard.File photo by Stephanie Mitchell/Harvard Staff Photographer
April 30, 2025
7 min read
To be honored on June 6 marking Alumni Day
Part of the
Commencement 2025
series
A collection of features and profiles cover
A collection of features and profiles covering Harvard University’s 374th Commencement.
The Harvard Alumni Association (HAA) has announced that Kathy Delaney-Smith, Paul J. Finnegan ’75, M.B.A. ’82, Carolyn Hughes ’54, and David Johnston ’63 will receive the 2025 Harvard Medal.
First awarded in 1981, the Harvard Medal recognizes extraordinary service to the University in areas that include leadership, fundraising, teaching, innovation, administration, and volunteerism. Alumni, former faculty and staff, and members of organizations affiliated with the University are eligible for consideration. The medals will be presented to recipients on Harvard Alumni Day on June 6.
Photo by Cheryl Clegg
Kathy Delaney-Smith
The all-time winningest coach of any sport — men’s or women’s — in Ivy League history and a trailblazer for gender equity, Kathy Delaney-Smith put Harvard basketball on the map and expanded its profile both nationally and internationally.
With 630 career victories, Delaney-Smith led Harvard Women’s Basketball to 11 Ivy League titles and 16 postseason appearances during her 40 seasons with the Crimson — the second-longest coaching tenure among NCAA Division 1 coaches. In honor of her illustrious career, the women’s coaching position was renamed the Kathy Delaney-Smith Head Coach for Harvard Women’s Basketball upon her retirement.
The first woman named to the Massachusetts Basketball Coaches Hall of Fame, Delaney-Smith has been honored for both her coaching abilities and her advocacy for gender equity in sports.
Her strong but caring coaching style was defined by her “act as if” mantra, which encouraged team members to carry themselves with the confidence of already having achieved their goals. She employed visualization, mindfulness, and sports psychology decades before they became commonplace, and throughout her long career has guided players through difficult experiences off the court. At the request of basketball alumnae, she wrote the book “Grit and Wit: Empowering Lives and Leaders,” published earlier this year.
Delaney-Smith came to Harvard in 1982 after compiling a 204–31 record at Westwood (Massachusetts) High School, with six undefeated regular seasons and one state title. During her tenure at Westwood, she worked to ensure that the girls’ team had sufficient resources. She also coached USA Women’s Basketball three times, including the team that won gold at the World University Games in Turkey in 2005.
A cancer survivor, Delaney-Smith has dedicated much of her time to helping the American Cancer Society and spreading the word of early detection, for which she received the Gilda Radner Award.
Paul J. Finnegan
Paul Finnegan has been a devoted and dynamic champion of Harvard for over 40 years, lending his expertise and steady voice to top leadership roles, including Harvard Corporation member, University treasurer, Harvard Overseer, chair of the Harvard Management Company, and HAA president. Guided by his passion for education and love for his alma mater, Finnegan has worked tirelessly to strengthen the University’s financial health, governance, and educational mission.
Finnegan was a member of the Harvard Corporation, the University’s senior governing board, for 12 years. From 2014 to 2023, he served as University treasurer, where his financial acumen and deep institutional knowledge informed the work of the University’s financial administration and guided major changes at Harvard Management Company, which he chaired from 2015 to 2024.
Finnegan was also a driving force behind The Harvard Campaign, planning and leading fundraising efforts as executive committee co-chair to raise a remarkable $9.6 billion — making it the most successful fundraising campaign in the history of higher education when it concluded in 2017.
A collegial leader admired for his down-to-earth nature and ability to see opportunities within challenges, Finnegan served from 2008 to 2012 as an elected member of the Harvard Board of Overseers, where he chaired the committee on finance, administration, and management. As HAA president from 2006 to 2007, he enhanced alumni communications systems and expanded global outreach.
Through the decades Finnegan has been closely involved with several Harvard Schools, serving on Harvard Business School’s Board of Dean’s Advisors, Harvard T.H. Chan School of Public Health’s Leadership Council, as honorary co-chair of the Harvard Graduate School of Education’s campaign, and the Faculty of Arts and Sciences’ Dean’s Council, where he spurred meaningful improvements to the undergraduate experience.
A member of the Committee on University Resources, Finnegan was chair of the HBS Fund and of the College Class of 1975 reunion committee. He is a longtime supporter of Teach for America.
Rocco Chilelli/Camelot Photography Studios LLC
Carolyn Hughes
Motivated by a passion for education and a commitment to helping future generations of talented students attend Harvard, Carolyn Hughes has been a loyal and celebrated Harvard volunteer and ambassador for nearly 50 years, interviewing countless high school students and engaging alumni through her leadership of the Harvard Club of Long Island.
Hughes grew up in Boston’s Allston neighborhood, the daughter of a prison guard and a homemaker. Though she had not planned to attend college, an eighth-grade teacher insisted she take the academic program and be prepared. Four years later she was admitted to Radcliffe and given partial funding through her high school. Research work on the melting icebergs in the Arctic Ocean paid for the rest. After Radcliffe, she moved to New York and taught herself computer science and systems design, joining the first cohort of women in the field.
Never forgetting the tremendous opportunities Radcliffe provided, Hughes began volunteering in the late 1960s, interviewing college applicants as a member of the Radcliffe Club of Long Island — before it eventually merged with Harvard — and personally visiting 120 of the area’s high schools. In the five decades since, Hughes has served as an HAA director for Clubs and SIGs, an elected director of the HAA, and chair of the National Schools and Scholarship Committee within the Harvard College Admissions Office.
With unwavering dedication, she has held nearly every leadership position in the Harvard Club of Long Island, including president, helping to develop robust programming and outreach. As chair of the Long Island Schools Committee, her role expanded to training Harvard interviewers and organizing guidance counselor programs. She now serves as co-chair emerita of the Club’s Schools and Scholarship Committee.
Hughes has received numerous commendations, including the HAA Award in 1990, the Hiram S. Hunn Award in 2002, and the HAA Clubs Award in 2020.
Credit: Sgt. Ronald Duchesne, Rideau Hall, OSGG
David Johnston
The 28th governor general of Canada, a former university president, and a professor of law for more than four decades, David Johnston has dedicated his life in service to his country, to academia, and to Harvard — where he brought his strength as a consensus-builder and commitment to excellence to a variety of roles, including president of the University’s Board of Overseers.
Growing up in a mining town outside Sudbury, Ontario, Johnston quickly learned that an education could open many doors. He was first approached by Harvard at age 14 on the advice of an alumnus who had heard he was a promising scholar-athlete. Johnston enrolled in the College in 1959 on a scholarship, excelling in his studies while also becoming a two-time All-American ice hockey player. He graduated magna cum laude and was later named to the Harvard Varsity Club Hall of Fame.
Dedicated to ensuring talented students from all backgrounds have access to the same opportunities that Harvard afforded him, Johnston has been a steadfast volunteer, serving on his class reunion and gift committees for decades, as an HAA elected director, and on several Overseers visiting committees — including athletics; arts and humanities; finance, administration, and management; and information technology.
Elected to the Board of Overseers in 1992, Johnston was named chair in 1997 — the first non-U.S. citizen to hold the position. In recognition of his service to the University, the Harvard Club of Ottawa established the David Johnston Financial Aid Fund for Harvard, which supports students from Canada.
Johnston was Canada’s governor general from 2010 to 2017. He also served as dean of the faculty of law at the University of Western Ontario, principal and vice-chancellor of McGill University, and president of the University of Waterloo.
Married 61 years, Johnston and wife, Sharon, have five daughters, all in public service, and 14 grandchildren.
Campus & Community
Garber announces new initiatives to fight antisemitism, anti-Israeli bias
Co-chairs for the Task Force on Combating Antisemitism and Anti-Israeli Bias Jared Ellias (left) and Derek Penslar.Photos by Niles Singer/Harvard Staff Photographer
Julie McDonough
Harvard Staff
April 29, 2025
long read
Actions come as task force releases full report
Harvard University will b
Garber announces new initiatives to fight antisemitism, anti-Israeli bias
Co-chairs for the Task Force on Combating Antisemitism and Anti-Israeli Bias Jared Ellias (left) and Derek Penslar.
Photos by Niles Singer/Harvard Staff Photographer
Julie McDonough
Harvard Staff
long read
Actions come as task force releases full report
Harvard University will build upon its previous work, as well as launch new initiatives and actions, to combat antisemitism and anti-Israeli bias, President Alan M. Garber announced on Tuesday. The actions laid out by Garber come in conjunction with the release of the final report and recommendations from the Presidential Task Force on Combating Antisemitism and Anti-Israeli Bias.
In his community message, Garber thanked the members of the task force “for pursuing their work with a spirit of openness, empathy, and compassion during a period of unrest within our community,” noting that their report is “the product of strenuous, prolonged efforts by some of the most generous and dedicated citizens of our University.”
The actions announced by Garber focus on three main areas: nurturing a widespread sense of belonging and promoting respectful dialogue; revising and implementing policies, procedures, and training; and strengthening academic and residential life. Building upon work the University has done over the last 15 months, the new actions include launching a major initiative to promote viewpoint diversity; dedicating resources to the creation of a research project focused on antisemitism; further review of disciplinary policies and procedures to assess their effectiveness and efficiency; and the expansion of resources to directly support students who experience antisemitism and other forms of discrimination.
Harvard’s Schools are actively reviewing task force recommendations concerning admissions, appointments, curriculum, and orientation and training programs, including those organized by recognized student groups. Deans will work to strengthen existing academic review processes for courses and curricula to ensure that they uphold the highest standards of academic excellence and intellectual rigor. Action plans designed for the College, the Graduate School of Arts and Sciences, and each professional School will be shared with the president’s office by the end of the spring term.
“The scope of recommendations made by both task forces underscores the breadth of the challenges we face. They must be addressed with determination at every level of the University by effectively tackling issues that arise where our students congregate or live; ensuring that expectations for both students and teachers in the classroom are clearly communicated and met; nurturing vibrant debate and open speech in ways that encourage everyone to express their ideas freely; preserving the right to protest and dissent while avoiding disruption, harassment, and threats; and, when our policies are violated, ensuring that our disciplinary processes are fair, consistent, and effective. If we intend to make significant and durable change across Harvard, it is critical that we act decisively in each of these areas,” Garber wrote in his message.
The release of the task force’s report and recommendations caps off an effort that began in spring 2024 to document the experiences of Jewish and Israeli students, faculty, and staff on campus.
Through a series of listening sessions, as well as an online survey last spring and summer, the task force gathered extensive feedback from students, faculty, staff, and alumni. Members were not charged with investigating the reports they heard, though participants were advised of University policies under which they could file formal complaints. Stories are described in the report as they were heard. The task force also completed a comprehensive historical analysis of the Jewish experience at Harvard from the 1920s to present.
The report includes findings and a set of recommendations designed to address antisemitism and anti-Israeli bias across the University. By reviewing concerns about select courses, events, and programs, the report also identifies specific areas where the task force feels the University can improve its approach to teaching about Israel and Palestine and to ensuring that all students feel free to express their opinions without fear or reservation.
Research and findings
The task force, whose members were appointed in late February 2024, began their work by hosting in March and April 2024 a series of listening sessions with students, staff, and faculty. Nearly 50 sessions were held with about 500 participants. Following the listening sessions, the Task Force on Combating Antisemitism and Anti-Israeli Bias joined with the Task Force on Combating Anti-Muslim, Anti-Arab, and Anti-Palestinian Bias in jointly issuing a University-wide survey.
From those who attended the listening sessions, several themes emerged related to the Jewish and Israeli experience on campus. Most notable was the deterioration of the campus climate after the terrorist attack on Oct. 7, 2023. Jewish students in general, and those who identify as Zionist in particular, felt that the climate had become less welcoming, even leading some to conceal their religious identity. Feelings of rejection and marginalization were common among Israeli students.
“The listening sessions provided a window into the real-time experience of Jewish students on campus, both inside the classroom and within the larger campus community,” said Jared Ellias, task force co-chair and the Scott C. Collins Professor of Law at Harvard Law School. “While specific incidents of antisemitism are of significant concern, there is also this larger issue of Jewish students feeling less of a sense of belonging at Harvard and less comfortable expressing their true selves and true identities.
The task force further explored programs, events, and courses at specific Schools that were perceived to be unbalanced in their approach to Israel and Palestine. In the report, task force members signal concern about these offerings and whether they are consistent with Harvard’s standards for excellence and academic integrity. The authors also argue that perceived bias in academic settings directly impacts the sense of belonging Jewish and Israeli students feel on campus.
The online survey of the Harvard community indicated that, across nearly every category, Jewish student respondents reported greater levels of discomfort and alienation than their Christian or atheist/agnostic peers. Though the number of individuals responding to the survey was not as high as similar University-wide surveys, the data allowed for a meaningful examination of the differences in responses by subgroup. Of the 2,295 respondents, 477 identified as Jewish. Jewish student respondents reported higher levels of concern about their physical and mental safety. They were also more likely to feel uncomfortable expressing their opinions and, in particular, their political opinions.
“Harvard makes a point of recruiting amazing students, staff, and faculty from all over the country and the world, and our work suggests that at some point in the recent past we stopped looking for ways to connect with one another as Harvard community members and started focusing on the issues that divide us,” Ellias said. “All the faculty on the task force were very surprised at how much student life had changed since we were college students.”
Many student respondents expressed concern about the University’s response to incidents of bias and were critical of both policies and the timeliness of responses. These concerns and experiences were exacerbated by what they saw from their classmates and, in some cases, teachers, on social media, which often served to amplify hostility and hateful rhetoric.
In addition to the qualitative and quantitative findings, the Task Force on Combating Antisemitism and Anti-Israeli Bias conducted a historical analysis of the Jewish experience at Harvard. This experience, the authors say, has been shaped by both the number of Jewish students on campus and the influence of world events on dialogue, discussion, and activism. The report finds the decline of respectful engagement regarding Israel and Palestine to be deeply troublesome and a significant contributing factor to the current campus climate.
“The historical analysis provided us with a unique lens into how the Jewish experience at Harvard has changed over time,” said Derek Penslar, co-chair of the task force and the William Lee Frost Professor of Jewish History in the Faculty of Arts and Sciences. “It is clear that world events have often influenced campus events and activities. However, it also became clear that civil discourse on the issue of Israel and Palestine has declined over time, signaling to the faculty that we must help our students learn to engage with each other in respectful ways even when we disagree.”
Final recommendations
In June 2024, the task force issued a set of preliminary recommendations that identified near-term opportunities to address areas of concern prior to the 2024-25 academic year. Those recommendations asked leadership to clarify University values; act against discrimination, bullying, harassment, and hate; improve student disciplinary processes; implement antisemitism and anti-Israeli bias education and training; foster constructive dialogue; and support Jewish life on campus.
The University rolled out a series of changes, including new campus and protest rules; centralized fact-finding in discipline cases across Schools; new training opportunities for faculty, staff, and students on identifying and preventing antisemitism; and new initiatives in the Schools for constructive dialogue and disagreement across differences.
In the final report, the task force has expanded upon these preliminary recommendations. The final recommendations fall into the following categories:
Admissions and early student experiences: The task force recommends a focus on attracting and admitting students who are eager to contribute to a learning community that is grounded in open inquiry and mutual respect. The report adds that once on campus, the University should ensure that these values and aspirations are emphasized in early student experiences.
Academics and academic offerings: The task force calls for the University to strive to ensure a classroom experience that is free from antisemitism, anti-Israeli bias, and all forms of discrimination. Moreover, the report recommends that the University’s academic offerings should include significantly more plentiful and diverse opportunities for the study of Jewish civilization, antisemitism and the Holocaust, Israel, and the Israeli-Palestinian conflict.
Co-curricular activities and residential life and pluralism: The task force recommends providing student organizations with support and guidance to ensure that their activities do not have antisemitic or anti-Israeli impacts, so that their activities enhance the Harvard learning community. According to the task force, this recommendation goes hand in hand with building a pluralistic community in which students can express diverse opinions and viewpoints.
Religious life: The task force recommends steps to strengthen religious life on campus, better supporting Jewish students and students of all faiths.
Administrative infrastructure and complaint mechanisms: The task force recommends a robust administrative infrastructure to support and coordinate efforts. This recommendation includes efforts to strengthen complaint mechanisms and to develop equitable disciplinary procedures across Schools.
Oversight: The task force calls for changes related to governance issues to strengthen ladder faculty oversight of educational programs and instructor training across Schools.
Read the full report of the Task Force on Combating Antisemitism and Anti-Israeli Bias, as well as President Garber’s message about the new University action plan and more information on the action steps Harvard has taken to respond to the concerns, information, and recommendations shared by the task force.
Campus & Community
Garber announces new steps to combat bias against Arabs, Muslims, and Palestinians
Co-chairs for the Task Force on Combating Anti-Muslim, Anti-Arab, and Anti-Palestinian Bias Wafaie Fawzi (left) and Asim Ijaz Khwaja.Photos by Niles Singer/Harvard Staff Photographer
Julie McDonough
Harvard Staff
April 29, 2025
long read
Moves come amid release of final report from task force
In his community message, Garber thanked the members of the task force “for pursuing their work with a spirit of openness, empathy, and compassion during a period of unrest within our community,” noting that their report is “the product of strenuous, prolonged efforts by some of the most generous and dedicated citizens of our University.”
The actions Garber announced focus on three main areas: nurturing a widespread sense of belonging and promoting respectful dialogue; revising and implementing policies, procedures, and training; and strengthening academic and residential life. Building upon work the University has done over the last 15 months, the new actions include launching a major initiative to promote viewpoint diversity; undertaking a comprehensive historical overview of Muslims, Arabs, and Palestinians at the University; and further review of disciplinary policies and procedures to assess their effectiveness in ensuring that every member of the community feels supported.
Harvard’s Schools are actively reviewing task force recommendations concerning admissions, appointments, curriculum, and orientation and training programs, including those organized by recognized student groups. Deans will work to strengthen existing academic review processes for courses and curricula to ensure they uphold the highest standards of academic excellence and intellectual rigor. Action plans designed for the College, the Graduate School of Arts and Sciences, and each professional school will be shared with the president’s office by the end of the spring term.
“The scope of recommendations made by both task forces underscores the breadth of the challenges we face. They must be addressed with determination at every level of the University by effectively tackling issues that arise where our students congregate or live; ensuring that expectations for both students and teachers in the classroom are clearly communicated and met; nurturing vibrant debate and open speech in ways that encourage everyone to express their ideas freely; preserving the right to protest and dissent while avoiding disruption, harassment, and threats; and, when our policies are violated, ensuring that our disciplinary processes are fair, consistent, and effective. If we intend to make significant and durable change across Harvard, it is critical that we act decisively in each of these areas,” Garber wrote in his message.
Last spring and summer, the task force gathered feedback from students, faculty, staff, and alumni through a series of listening sessions and a joint task force survey. In addition, the task force explored how salient events at the University over the past year and key world events over the last several decades impacted the campus climate.
The final report includes findings and a set of recommendations designed to address feelings of abandonment and silencing described by many Muslim, Arab, Palestinian, and pro-Palestinian members of the Harvard community, especially following the Oct. 7, 2023, attacks and their aftermath. Through a review of the concerns raised by community members, the report outlines how the University can improve safety and anti-discrimination policies, uphold free expression and open inquiry inside and outside of the classroom, rebuild institutional trust through an emphasis on equal access and transparency, expand faculty and academic offerings that provide a more comprehensive and representative view of the histories, beliefs, and cultures of Muslims, Arabs, and Palestinians, and related topics.
Research and findings
Task force members were appointed in late February 2024 and began their work in early April 2024, hosting a series of listening sessions with students, staff, and faculty. Nearly 50 sessions were held with an estimated 500 participants. Following the sessions, the Task Force on Combating Anti-Muslim, Anti-Arab, and Anti-Palestinian Bias joined with the Task Force on Combating Antisemitism and Anti-Israeli Bias in issuing a University-wide survey that garnered 2,295 responses. The task force was not charged with investigating reports, but participants were advised of University policies under which they could file formal complaints. Stories were described in the report as they were heard.
From those who attended the gatherings, five themes emerged: descriptions of experiences of discrimination and hate against Muslim, Arab, Palestinian, and pro-Palestinian members of the Harvard community; dissatisfaction with institutional response to incidents of bias and hate; growing divisions, self-censorship, and alienation within the community; concerns about educational experience and a desire for a more inclusive curriculum reflecting global complexities; and calls for divestment as a means for Harvard to address ethical concerns regarding the Israeli-Palestinian conflict.
In addition to describing these themes, the report also notes that the history of Muslims, Arabs, and Palestinians at Harvard reflects a complex and evolving narrative. It starts with a limited presence on campus in the 17th and 18th centuries confined mostly to theological studies. It was followed in the 20th and 21st centuries by a period of increasing Muslim, Arab, and Palestinian diversity among students and activism fueled by global events such as the Israeli-Palestinian conflict. Throughout this latter period, and due to events like the 9/11 terrorist attacks, Muslims, Arabs, and Palestinians reported facing marginalization, discrimination, misrepresentation, and silencing. According to the report, these issues continue today and now affect an even wider set of community members.
The survey also highlighted significant disparities in feelings of safety, belonging, and freedom of expression across religious and racial lines. The data included responses from individuals who self-identified as Muslim, Jewish, Christian, and atheist/agnostic/spiritual. Though the number of individuals responding to the survey was not as high as similar University-wide surveys, the data allow for a meaningful examination of the differences in responses by subgroup. Respondents who described themselves as Muslim and Middle Eastern and North African (MENA) reported some of the worst outcomes on various measures of safety and belonging and freedom of expression: 47 percent of Muslims and 35 percent of MENA respondents felt physically unsafe on campus, and 92 percent of Muslims and 83 percent of MENA respondents felt there were academic/professional penalties for expressing political views. In examining contributing factors, respondents indicated that interactions within the Harvard community with faculty and peers were largely positive, whereas interactions with outside influences were generally perceived negatively.
“The listening sessions, combined with the University-wide survey, brought to light so much of the pain, struggle, and fear that those in the community here at Harvard were experiencing,” said Asim Ijaz Khwaja, task force co-chair and Sumitomo-Foundation of Advanced Studies in International Development Professor at Harvard Kennedy School. “It is critical that we document the experiences and biases faced by Arab, Muslim, Palestinian, and pro-Palestinian members of our community through regular and systematic data gathering and analysis. This will enable us to better understand and address their concerns.”
Final recommendations
Following the review of qualitative findings last spring, the task force provided preliminary recommendations to President Garber in June 2024, which identified urgent issues the task force believed should be addressed prior to the start of the next academic year. Those recommendations included actions related to safety and security, recognition and representation, institutional response, freedom of expression, transparency and trust, relationships among affinity groups, and intellectual excellence. The University pursued a series of changes including new campus and protest rules, centralized fact-finding in discipline cases across Schools, new training opportunities for faculty, staff, and students on identifying and preventing anti-Arab, anti-Muslim, and anti-Palestinian biases, and new initiatives at Harvard’s Schools for constructive dialogue and disagreement across differences.
In the final report, the task force expanded upon these preliminary recommendations and proposed additional ones.
“These recommendations align with Harvard’s academic mission by prioritizing the safety and security of our students, faculty, and staff, and aiming to ensure their full participation in the pursuit of knowledge while guaranteeing that all voices are heard and respected,” said Wafaie Fawzi, task force co-chair, Richard Saltonstall Professor of Population Sciences, and professor of Nutrition, Epidemiology, and Global Health at the Harvard T.H. Chan School of Public Health. “The University can support this mission by ensuring the institutional supports are in place — policies, procedures, and protocols — but also by providing opportunities for our community within and across affinity groups to come together and engage with each other.”
A summary of the final recommendations includes:
Safety and security concerns: The task force recommends continuing to address issues in this area expressed by Muslim, Arab, Palestinian, and Pro-Palestinian students, staff, and faculty. This includes both those involving physical and mental health. The recomendations include investing in culturally competent mental health support, offering comprehensive resources and training to combat doxxing, and formally defining instances of Islamophobia, anti-Arab, and anti-Palestinian bias within University policies.
Recognition and representation: The report recommends establishing a standing advisory committee of faculty and specialists well-versed in areas pertinent to Middle Eastern history to guide policy, programming, and University responses. It further calls for providing regular and ongoing in-person training for stakeholders and actively supporting programming on key community issues to enhance civil discourse and intellectual vitality within the University. The task force also recommends undertaking a comprehensive historical overview of Muslims, Arabs, and Palestinians at Harvard to address bias and promote inclusivity on campus.
Institutional response: The task force calls for adopting clearly communicated, user-friendly, and transparent processes for bias incident complaints and anti-discrimination and anti-bullying procedures. The report also suggests establishing support roles to help manage and guide complainants through these protocols.
Freedom of expression: The task force recommends not only adopting policies to protect open academic inquiry, constructive dialogue, and active demonstrations of freedom of expression, but also proactively encouraging and supporting these efforts and providing safe spaces to exercise them. According to the report, clear and transparent policies should exist to manage protest and counterprotest activities, and it should be clearly communicated that the University celebrates community members exercising free speech, provided they respect time, place, and manner restrictions.
Transparency and trust: The task force recommends developing a shared policy framework adaptable by individual Schools, ensuring consistent understanding and flexible application across the University while recognizing the need for School-specific variations. The report suggests a unified communications strategy for these and related policies should be developed. In addition, the task force states that greater transparency and disclosure is needed on issues raised by some community members, such as divestment and greater engagement in the Middle East, including supporting Palestinian and other universities in the region and facilitating exchanges.
Relationships among affinity groups: To strengthen relationships between and within the community at Harvard, the task force recommends creating dedicated permanent spaces and programming that can address the diverse needs of the Muslim, Arab, Palestinian, and pro-Palestinian community. To facilitate community relationships, both task forces call for a central hub for pluralism efforts. In addition, the report proposes a University-wide Office of Religious, Spiritual, and Ethical Life to bolster multifaith work. As envisioned by the task force, these efforts would connect pluralism and multifaith practices across disciplines and enhance programs like interfaith collaborations and cultural events.
Intellectual excellence: As core to the mission of Harvard University, the task force emphasizes the need to enhance the intellectual experience on campus. The report suggests this could include expanding academic offerings by recruiting faculty and increasing courses on Palestinian studies and Arabic language, designing experiential learning programs to address issues like antisemitism and anti-Palestinian biases, and engaging in more University-wide dialogues on crisis issues, alongside existing campus efforts to model respectful dialogue. The task force also calls for leveraging regular surveys, like the Pulse survey, as well as building the capacity to collate and analyze administrative data to monitor community well-being and address key issues on an ongoing basis.
The full report of the Task Force on Combating Anti-Muslim, Anti-Arab, and Anti-Palestinian Bias can be found here, as well President Garber’s message about the new University action plan, and more information on the action steps Harvard has taken to date to respond to the concerns, information, and recommendations shared by the task force.
Work & Economy
Can Trump fire Fed chairman?
U.S. Federal Reserve Chairman Jerome Powell at a news conference following a Federal Open Market Committee meeting in March. Photo by Sha Hanting/China News Service/VCG via AP
Christina Pazzanese
Harvard Staff Writer
April 28, 2025
8 min read
Law professor and former Fed Board member says it’s possible but likely market reaction should give pause
U.S. Federal Reserve Chairman Jerome Powell at a news conference following a Federal Open Market Committee meeting in March.
Photo by Sha Hanting/China News Service/VCG via AP
Christina Pazzanese
Harvard Staff Writer
8 min read
Law professor and former Fed Board member says it’s possible but likely market reaction should give pause
President Trump has had a difficult relationship with Federal Reserve Chair Jerome Powell.
Concerns over Trump’s global tariff plans roiled markets earlier this month. Powell, who was first nominated to the post by Trump in 2017, noted the president’s policies could lead to higher inflation and slower growth.
Trump accused the Fed chair of failing to boost the economy by not being more aggressive about cutting interest rates. (The two also disagreed over rates in Trump’s first term.) He also hinted he was contemplating ousting Powell before his four-year-term expires next year, further unsettling markets.
In this edited conversation, Daniel Tarullo, Nomura Professor of International Financial Regulatory Practice at Harvard Law School, discusses the potential fallout should the president make good on his threats to fire Powell. Tarullo served on the Federal Reserve Board and the Federal Open Market Committee (FOMC), the body that decides on interest rates, from 2009 to 2017.
The Federal Reserve Act of 1913 allows governors to be removed for cause, but it doesn’t say anything about the FOMC chair. In your view, does a president, as head of the executive branch, have the power to oust Powell?
There are two separate issues. One is a statutory interpretation issue — whether the addition of the amendment to the Federal Reserve Act in the 1970s, which provided for Senate confirmation of the chair for a four-year term, incorporates the “for cause” protection the original Federal Reserve Act afforded to all members of the Board of Governors.
The alternate reading would be that the four-year term for the chair as chair is not protected by the “for cause” provision.
The second issue, of course, is whether — regardless of what the Federal Reserve Act provides — the Supreme Court believes that the Constitution gives the president removal power for anybody at an independent agency who is performing what the court considers to be “executive” functions. Those two issues are related, but in the first instance, they’re actually distinct.
Daniel Tarullo.
Manuel Balce Ceneta/AP file photo
Is the Supreme Court likely to support such a move given recent decisions on the scope of executive authority?
I think most observers expect some further erosion of the famous 1935 decision Humphrey’s Executor, which for 85 years was understood as validating “for cause” protection for the principals at independent agencies.
Whether the court will further erode Humphrey’s step by step or will sweep it away in a single case remains to be seen.
The issue, though, would be whether the Fed (and perhaps other agencies) would be treated differently. And I think we’ve seen some hints from three of the conservative justices — Samuel Alito, John Roberts, and Brett Kavanaugh — that they may regard the Federal Reserve differently from other agencies.
They may still hold a broad view of the president’s authority, but favor a carve-out for the Fed?
Yes. None of the three justices has done more than hint at a potential difference, so we don’t have a sense of what their basis for distinction would be.
One that is available is the legacy of the Federal Reserve in the First and Second Banks of the United States. There could be an argument that from the very first Congress, which convened right after the Constitution was ratified, there was an acknowledgement that Congress could create an independent central bank.
Now, the First Bank of the United States was not a central bank as we would think of it today, but in the late 18th century it was pretty close to what was then thought of as a central bank, epitomized by the Bank of England. So that argument would be available. It’s not overwhelmingly compelling, but it’s arguable. Besides, I haven’t thought that the court’s recent decisions on the “for cause” removal protection have themselves been compelling, so there is an opportunity for the court to do some picking and choosing.
Is there a good legal argument for removing Powell before his term ends?
We can go back to the fact that for 85 years “for cause” protection in independent agencies was generally thought to be the prevailing doctrine.
But the Supreme Court gave substantial reason to question that proposition in Seila Law, the 2020 case that found Congress’ grant of “for cause” removal protection to the head of the Consumer Financial Protection Bureau to be unconstitutional.
So, it’s the court which has changed that 85-year-old understanding and left unanswered the question of how broadly it will ultimately rewrite Humphrey’s Executor.
If there were an effort by the president to remove the chair, the market reaction would be very significant — well before any court had an opportunity to pass on the issue. The anticipated market effect is a disincentive to try to remove the chair, no matter how unhappy the administration may be with his policies.
Given Powell’s term as chair now has only a year to run, that’s probably an additional argument for just waiting until the president can name his own person as a successor. And so, at some level, the market is as much a protection for the Board of Governors as the law may end up being.
Why is Wall Street rattled by the prospect of Powell removal?
Sitting administrations will almost always favor a looser monetary policy in order to promote near-term economic growth. The point of having some independence for a central bank is that the central bankers can look at the potential impact on inflation over the medium term and try to keep inflation closer to what today for the Fed is a 2 percent target. It’s a pretty simple rationale, but it’s a powerful one.
What markets fear is that if a president removes the chair or other members of the Board of Governors, it would be with the intent of having a looser monetary policy. At that point, the markets’ trust in the central bank will be substantially undermined, and thus, the central bank’s credibility as an inflation fighter will be undermined. Longer-term interest rates will then rise, probably dramatically.
Thus, there’s the potential for an odd situation in which the Fed central bank is more responsive to the administration’s desire for near-term growth and reduces short-term rates, but markets, thinking that’s going to be inflationary, essentially demand a higher premium for holding longer-term Treasuries and other longer-term debt. It’s for that reason that I believe that any action by any administration to try to remove the chair or other members of the board is ultimately self-defeating.
Secretary of the Treasury Scott Bessent has quite understandably been focused on the 10-year Treasury rate, because that rate is very important for investment decisions throughout the economy. One would presume the administration doesn’t want to drive up that rate because of uncertainty in markets.
How much power does the chair actually have over internal policy deliberations?
There’s still some significant public misperception on just how powerful the chair is within the board and within the FOMC.
For a period when Alan Greenspan was chair, his preferences and decisions apparently more or less drove FOMC decisions. By the time I joined the Board of Governors in early 2009, that was certainly not the case. I think Ben Bernanke, Janet Yellen, and now Jay Powell have all had to do a substantial amount of internal consultation and internal work trying to forge a consensus around monetary policy.
There’s no question that the chair is far and away the most important individual on the FOMC. But it’s not the case that the chair can simply dictate what policy is going to be and the rest of the FOMC will fall into line.
If Powell was replaced by someone with a certain pedigree, would that calm market jitters?
I think if there were an effort to remove him, the identity of the successor wouldn’t be all that consequential because I believe markets would read into the very act of removal an intent to have a significantly more accommodative monetary policy.
If Jay Powell is allowed to serve out his four-year term, then obviously the identity of the individual whom the president nominates to succeed him will be of substantial interest to markets.
Campus & Community
Pulse Survey finds strong sense of belonging and respect at Harvard
Widener Library in Harvard Yard.File photo by Grace DuVal
Julie McDonough
Harvard Correspondent
April 28, 2025
8 min read
Gaps identified, particularly related to sharing opinions and forming relationships with people holding different views.
Survey results released by Harvard Monday find a strong
Pulse Survey finds strong sense of belonging and respect at Harvard
Widener Library in Harvard Yard.
File photo by Grace DuVal
Julie McDonough
Harvard Correspondent
8 min read
Gaps identified, particularly related to sharing opinions and forming relationships with people holding different views.
Survey results released by Harvard Monday find a strong sense of belonging among community members, but lower levels of comfort sharing opinions and forming relationships across differences. The new data was released as part of a report of the Pulse Survey on Inclusion & Belonging.
First piloted in 2019 following a recommendation of the Task Force on Inclusion & Belonging, the survey seeks to take the “pulse” of the community and gauge the climate around inclusion and belonging of the entire campus community. Administered for the second time in September 2024, the survey asked every member of Harvard — students, faculty, researchers, and staff — to share their personal experience as an individual interacting with peers, and with the institution as a whole. The results will be integrated with other survey data and used to make improvements to programming related to culture and community.
“The Pulse Survey is a valuable tool for assessing how members of our community experience the University and understand their place in it,” said President Alan M. Garber. “The insights it provides will help guide us as we work toward creating a culture in which each of us feels included, respected, and valued.”
To understand the results of the survey, including areas of strength and areas for improvement, the Gazette sat down with Sherri Charleston, chief community and campus life officer, and Drew Allen, associate provost for institutional research and analytics. They shared key findings and next steps for improving campus culture related to inclusion and belonging.
Sherri, I see that you have a different title, and the name of your office has changed. Can you tell me how those changes came about?
Charleston: Over the past five years, we have evolved to direct a variety of services on campus. I started in 2020 as the chief diversity and inclusion officer, leading the Office for Diversity, Inclusion, & Belonging. Given the high-level outcomes of the last Pulse Survey, President Garber decided to rename the portfolio to Community and Campus Life to align with its current focus — building community and increasing belonging. As we administered the Pulse Survey again last fall and considered the best way to communicate all the services we offer, it seemed like the right time to adjust my title to better reflect what the offices under my direction do for our campus community.
Sherri Charleston.
Harvard file photo
Tell us more about the Pulse Survey.
Charleston: The Pulse Survey provides a snapshot of how we are faring as a University community relative to inclusion and belonging goals across a variety of metrics. Because it is a “pulse” and not an “MRI,” it is meant to provide us with data that is directional in nature, rather than diagnostic. It can then be supplemented with other survey data to provide a fuller picture of the climate here at Harvard relative to inclusion and belonging.
Allen: It is rare that we have a survey that allows us to hear directly from every member of our community — students, faculty, researchers, and staff. The data are powerful because they point us in the right direction and provide a catalyst for more specific efforts to examine inclusion and belonging at Schools and units across campus.
What did the survey ask and how many individuals responded?
Charleston: The survey questions sought to examine the full breadth of human experience levels at Harvard: individual, community, and institutional. The survey looked specifically at four dimensions of inclusion and belonging: sense of value, acceptance and integration, connection across difference, and supportive assets. We wanted to gauge if individuals felt valued, respected, and recognized. We also wanted to know if they were comfortable expressing themselves and forming meaningful relationships with other community members, including those with viewpoints different than their own.
Allen: Importantly, this survey was taken by over 10,000 members of the Harvard Campus community, representing approximately 20 percent of the population. Given the response rate, which is in line with response rates of similar surveys in higher education, we feel confident that the data give us a valuable pulse of the Harvard community and can provide important direction for future initiatives and resource allocation.
What are the key highlights from the 2024 Pulse Survey data?
Charleston: The survey showed that large majorities of our respondents — students, faculty, researchers, and staff — feel like they belong at Harvard (including 78 percent of students, 81 percent of staff, and 75 percent of faculty and academic personnel). Respondents also generally feel respected (80 percent of students, 79 percent of staff, and 74 percent of faculty/academic). These numbers are very promising, but of course, come with the caveat that there are portions of our community who do not feel like they belong and do not feel respected.
We also found that while most members of our community feel comfortable sharing opinions with others and have been able to form relationships with people who have different viewpoints, it is not as high as we would like it to be. So, this is another area that we will want to explore to consider how we can effectively expand and strengthen efforts like the President’s Building Bridges Fund, which funds student-driven programs to bring community members together across differences.
Allen: As Sherri points out, the survey did show that the majority of students do feel like they can be their authentic selves here at Harvard. In some cases, our data showed an even higher level of positivity than in 2019 when the survey was first administered. The survey provides us with solid data to inform our decisions moving forward.
Drew Allen.
How will the University use the data?
Charleston: We will use this data to improve the experience of belonging and connection on campus, particularly across differences. The learnings from this survey can be used directionally to help us make decisions around where we need to allocate resources, both in terms of capacity and focus.
Allen: I think the data can also be used to identify areas of further analysis. A survey is just one method by which we can try to understand inclusion and belonging, but there are other methods we can use to try to understand something that is difficult to measure directly. The Pulse Survey data will guide us to develop additional lines of inquiry that our institutional research office can pursue so that we can better understand our community and their needs.
What improvements or changes were made on campus after the Pulse Survey was administered in 2019?
Charleston: There has been a real focus on strengthening our community and increasing the sense of belonging here on campus. One specific example was the establishment of the Harvard Culture Lab Innovation Fund (HCLIF). Funded by the President’s Office, HCLIF supports project ideas that foster a culture of belonging on campus. Grants are awarded to teams that aim to have a direct impact on the University community, engage the broadest audience, and align with the University’s goals toward excellence.
In addition to HCLIF, we have leaned into both building digital communities and building communities in person on campus. Our office newsletter has about 16,000 subscribers and allows us to share information across many different communities. We have also focused on building communities on campus through our now annual forum, providing community spaces to combat isolation and polarization, and working with colleagues to promote opportunities for community support. Recently, we awarded funding through the President’s Building Bridges Fund to student-led projects designed to build connection and community across differences.
What are your next steps and when can we expect the next Pulse survey?
Charleston: Our first step will be to convene community members to help us think about what we have learned and how we can use this data moving forward. Another piece is for us to think about how the various surveys that the University has conducted over the past few years fit together and how we can integrate those findings. We can use this opportunity to ground our decision-making in data and ensure we take actions that will support and improve the sense of belonging and community at Harvard.
Allen: When we consider when to do this survey again, we want to make sure that enough time has passed so that we can measure meaningful progress. Consistency and timing for the next survey will be important so that the data we collect is valuable and informative.
Health
How halt in funding hurts efforts to ensure safety of patients in medical research
Anna Lamb
Harvard Staff Writer
April 28, 2025
6 min read
Stop-work order disrupts system that facilitates oversight of studies happening at multiple sites
The Trump administration’s freeze of more than $2 billion in federal research grants to Harvard has disrupted work in a number of areas, includ
How halt in funding hurts efforts to ensure safety of patients in medical research
Anna Lamb
Harvard Staff Writer
6 min read
Stop-work order disrupts system that facilitates oversight of studies happening at multiple sites
The Trump administration’s freeze of more than $2 billion in federal research grants to Harvard has disrupted work in a number of areas, including efforts to ensure the rights and safety of patients who take part in medical studies.
The administration sent the University a stop-work order for the SMART IRB federal funding contract on April 14. The notice came hours after Harvard rejected government demands that included changes to governance and hiring practices and “audits” of viewpoints of students, faculty, and staff, among other measures.
SMART IRB is a national system administered by a Harvard Catalyst team along with other collaborators. It is used by hospitals, universities, and federal agencies to facilitate oversight of medical research taking place at multiple sites.
Barbara Bierer is the principal investigator and program director of SMART IRB and director of the Regulatory Foundations, Law and Ethics Program at Harvard Catalyst, the University’s clinical and translational science center. She is also a professor of medicine at Harvard Medical School.
In this edited conversation, she outlines how the funding cuts will impact patients who take part in research.
How do NIH funds go toward protecting patients?
Generally research, including NIH-funded research involving human participants, must be reviewed, approved, and then overseen by an institutional review board (IRB) to ensure compliance with applicable institutional, local, state, and federal rules, policies, laws, and regulations, as well as to ensure the rights and welfare of research participants.
For most universities and research institutions, IRB review and oversight are included as indirect costs in the research lifecycle. An NIH policy introduced in 2018 and applied more broadly to federally funded research in 2020 has also required multisite, collaborative research to be reviewed by a single IRB (an sIRB), which takes on the responsibility of reviewing and overseeing the research for all sites.
In some of these cases, the costs may be considered direct costs paid for by federal funding.
What role do these IRBs play in protecting patients?
IRBs, which are set up within — or independently work with — hospitals, universities, and other centers that conduct research, play a key role in carefully reviewing research proposals to ensure participants are protected in a number of ways.
These include consideration of the research question and study design, of recruitment plans, the process for obtaining and continuing to ensure informed consent, assessment and mitigation of risks of harm, participant safety, the determination of the relationship of adverse events to the research, data monitoring, etc.
“Every citizen who has benefited from the efforts of clinical research — taking a new drug, using a medical device, or undergoing a diagnostic test — is impacted by the way we conduct and monitor research.”
IRBs and the human research-protections programs also work to train and support investigators, manage interactions with sponsors, and work with federal and state regulators, among other responsibilities.
Think of IRBs as the “checks and balances” system that maintains the ethics and oversight that medical research studies need. Without this dedicated group of professionals and community members, our studies could potentially, and even inadvertently, cause harm to the individuals and communities that participate. Our valued federal laws and regulations were developed and continue to evolve in response to very real examples of such harms.
Across the U.S., thousands of people dedicate their careers to supporting the ethical oversight and conduct of research, working together every day to safeguard those of us who volunteer to take part in a study.
And of course, every citizen who has benefited from the efforts of clinical research — taking a new drug, using a medical device, or undergoing a diagnostic test — is impacted by the way we conduct and monitor research.
Where do we see this work have the biggest impact?
Concern for the safety, well-being, and protection of study participants drives this community of professionals. We make sure that a system exists for potential study participants to understand the research plan, risks, benefits, and burdens, and freely choose whether or not to participate in the research.
The IRB is also a resource to participants should they have questions or concerns about their participation in a study.
IRBs were the result of historical events that highlighted the need to monitor ethical issues that arise with human research. Can you talk about that a bit?
History has proven what’s at stake: the horrors of medical experimentation by German scientists during World War II; the tragic 1932-72 untreated syphilis study at Tuskegee that upended the public’s notion of safety and consent in medical trials and led to the system of oversight we have today in an act signed by Richard Nixon in 1974; the hepatitis studies at the Willowbrook State School for Children where children with developmental disabilities were intentionally infected with hepatitis; and the betrayal of trust and the principle of informed consent in genetic research involving members of the Havasupai Tribe.
Furthermore, our ability as a nation to advance scientific research is at stake. Imagine you have a dozen or more hospitals and universities across the country working on a new therapeutic that could treat Alzheimer’s disease. Before SMART IRB was available, these centers would have spent countless hours and faced numerous hurdles and delays just to collaborate. The process that is now available has reduced many of these blocks to innovation.
How will funding cuts impact this work?
Broadly, the increasingly expansive cuts to research funding, the cancellation of countless grants and contracts at exceptional research institutions across the country, will have a significant negative impact on research participants as well as on the IRBs and research professionals.
Studies halted midstream risk significant harms to participants and communities and can reinforce public skepticism and mistrust for the research enterprise and inhibit the commitment of researchers and institutions to fully, honestly, and collaboratively work with the communities they serve.
Since SMART IRB received a stop-work order on April 14, ongoing studies cannot add new clinical sites, more than 25 institutions have been prevented from joining, and dozens and dozens of research studies have been delayed.
At present, support from Harvard Medical School is allowing our team to continue the essential work of supporting collaborative research across the nation. It is our intention to continue to do so: The risks are too great, and the health and safety of the American people depend on it.
Arts & Culture
Discoveries on a musical path
Yosvany Terry.Credit: @stagetimearts
Julie McDonough
Harvard Correspondent
April 28, 2025
9 min read
From Benin to Cuba to the Americas, Yosvany Terry sees how tradition safeguards culture and identity
During recent travels to the West African nation of Benin and to Cuba, his home country, internationally renowned musician and composer Yos
From Benin to Cuba to the Americas, Yosvany Terry sees how tradition safeguards culture and identity
During recent travels to the West African nation of Benin and to Cuba, his home country, internationally renowned musician and composer Yosvany Terry began to research the link between the musical traditions of Benin and the Caribbean.
He had the opportunity to visit with, learn from, and perform alongside musicians keeping those traditions alive. Now Terry, a senior lecturer on music and director of the Harvard Jazz Ensembles, intends to bring his findings to the classroom and his own performances, including one on May 1 as a part of ArtsThursdays.
In this edited conversation, the Gazette sat down with Terry, who shared insights into his research, the importance of expanding the arts through cross-departmental collaboration, and what he likes best about working with Harvard students.
Tell us about your most recent research project.
My research in Benin (the former Kingdom of Dahomey) in January, as well as the research I have conducted in Cuba over the years, is meant to better understand the roots of modern jazz and the impact of the African diaspora on musical traditions.
Going to Benin and visiting remote regions was an opportunity to engage with musicians, learn from them, and perform with them. I could sit with people who are steeped in this culture and its traditions. It was in those magic spaces where they shared their cultural treasures with me. These musical and cultural traditions are not often researched. My Cuban heritage and personal connections to this culture allowed me to be able to connect with the practitioners I met in Benin and to have access to the traditions they continue to practice.
West African musical and cultural traditions came to the Americas with the slave trade, and this profoundly influenced the music that grew as a result of contact with these African traditions.
As we know, slavery ended much later in Cuba than elsewhere. Slaves closely guarded their cultural traditions. Safeguarding these traditions became a part of their rebellion and a way of maintaining their cultural identity under pressure to assimilate. This movement of resistance allowed them to keep the music, dance, culinary arts, spirituality, and religious practices of the societies they came from.
What will you do with this research?
My plan is to give my students access to this primary source material. I want them to know how these traditions prevailed and were safeguarded, but also how they influenced the musical traditions of Cuba, Haiti, Brazil, and the development of American jazz. With this information we can explore how this music influences popular culture and more deeply, how it becomes part of the fabric of who we are — our identity. One of my missions as an artist and an educator is to give life to this incredible wealth of information and culture that gets overlooked. It is so much a part of our daily life, but for so many, we don’t know where it comes from.
“One of my missions as an artist and an educator is to give life to this incredible wealth of information and culture that gets overlooked.”
What impact will it have on you as a musician and composer?
As an artist, this research allows me to create a new body of work that is in conversation with these traditions. I may base new compositions on this research, or I may be inspired to create a new avenue of exploration and inquiry.
I am now working on writing an opera, which is based upon the life of the first free person of color who organized the first rebellion against the Spanish colonial system in 19th-century Cuba. It is relevant today because the core of this work is unearthing a history that has been overlooked or forgotten.
While I was in Benin, I also traveled with a friend, Davey Frankel, a great filmmaker who was filming and documenting our conversations with historians, musicians, and the people of Benin who still practice these music and cultural traditions. The hope is to create a documentary that would connect the dots between the old Kingdom of Dahomey and today’s jazz music.
As director of the Harvard Jazz Orchestra, what is your vision for students who participate in that group?
I was fortunate to inherit a program that Tom Everett founded in 1972. It became an important jumping-off point for jazz at Harvard because it created space for jazz masters to visit the University. With support from the Office for the Arts at Harvard, it grew into something that the University really embraced, naming more than 120 jazz masters.
Part of what I have done to advance the jazz program is to support the engagement of artists of Afro Latin American descent and to make this a fixture of the band. By inviting jazz masters from all different musical backgrounds, including Chucho Valdés, Angélique Kidjo, Gonzalo Rubalcaba, and collaborating with other departments, we have expanded the scope and learning of students who participate. When we bring in artists of this caliber, we get feedback that this experience “changes students’ lives” Whether they decide to become professional musicians or simply to become lifelong supporters of the arts, we have planted the seed that stays with them.
The other piece I have emphasized with the jazz program is to learn from travel. We have visited Cuba and Dominican Republic, which are countries that students may not have otherwise chosen to visit on their own. These educational trips are not centered on tourist attractions, but rather on real learning from educators and other students in these countries. Our students hear lectures from masters of these musical traditions, including jazz band directors and professors. They engage with other music students in concerts and in jam sessions. These educational trips provide unique experiences that students tell us will stay with them for a very long time.
You have participated as a performer in ArtsThursdays a few different times. How has this programming raised the profile of the arts at Harvard and in the larger community?
ArtsThursdays, an initiative of the Harvard University Committee on the Arts (HUCA), has been vitally important to raising the visibility of art-making at Harvard, not only within Harvard but beyond Harvard into our surrounding communities. It has exposed these communities to the incredible work that is done by Harvard faculty who are active artists and performers, by inviting them to free concerts. Not only does it provide unique opportunities for faculty to engage with other artists, but it inspires students to imagine new possibilities. Importantly, it encourages art creators, students and faculty, to reach out across disciplines within the University, but also to bring artists in from other communities.
I am performing at ArtsThursdays again on May 1. At that performance, you will see a direct connection to the research that I did in Benin and Cuba. It reveals the way in which an artist moves from idea to performance — you can see the full circle — artist research, art-making and creation, and then finally, performance.
In conjunction with the May 1 performance, we are planning a dance workshop to engage dance students with these musical traditions. This is an example of the way in which ArtsThursdays inspires collaboration between departments that are not always in conversation. It’s a collaboration that could grow and might show up in our curriculum or classroom teaching in the future.
What is your favorite thing about teaching at Harvard?
Harvard students are, of course, very smart students who really want to learn. They have an enormous sense of curiosity. But many come to our department without knowing very much about the music or genre they are studying. Over the semester, it is so rewarding to see them grow and at the end, it’s possible to see how these courses have transformed their understanding of jazz and its history. They have this new wealth of information that they will take with them, and they become advocates for the information they have learned.
For me as an educator and composer, I love the collaboration with my colleagues across the different departments. I imagine the things you can do with collaboration in unusual departments. For example, I am working with my colleague Demba Ba, the Gordon McKay Professor of Electrical Engineering, on how we can use AI on creative aspects of composition. We are asking the question about how we can train new models to better learn and use aspects of certain musical traditions that AI has not been able to because of the death of data — traditions from West Africa, for example. Basically, how can we teach the system elasticity? This collaboration is exciting and important.
You have been at Harvard for 10 years. What is your hope for the arts in the next 10 years?
Since 2015 I have seen a lot of changes and growth, particularly in our music department. Those changes can be seen in what was offered before and what is offered now. We have been intentional about expanding our offerings to include different musical traditions. By doing so, we are now seeing a broader group of students coming through our department.
Of course, we cannot be complacent. We must continue with initiatives like HUCA, as well as inviting visiting artists and professors and hosting jazz masters in residence. We need to bring the brightest artistic minds to Harvard to spend time here in order to create new spaces for arts understanding. We need to push for new ways to reimagine arts at the University so that we have a healthy, robust, and diverse arts presence on our campus.
Photos by Niles Singer/Harvard Staff Photographer
Health
Weighing cure for sick kids against troubling ethical questions
Science Center talk outlines potential and risks of gene editing
Clea Simon
Harvard Correspondent
April 28, 2025
4 min read
If our differences are part of what make us human, do we have the right — or the responsibility — to change them? That question was at the crux of
Weighing cure for sick kids against troubling ethical questions
Science Center talk outlines potential and risks of gene editing
Clea Simon
Harvard Correspondent
4 min read
If our differences are part of what make us human, do we have the right — or the responsibility — to change them? That question was at the crux of “The Promise and Peril of CRISPR,” a talk given by Neal Baer, Ed.M. ’79, M.D. ’96, co-director of Harvard Medical School’s master’s degree program in Media, Medicine, and Health. At the Science Center presentation co-sponsored by the FAS’ Division of Science and Harvard Library, Baer discussed the ethical issues surrounding the gene-editing technology with Rebecca Weintraub Brendel, director of the Medical School’s Center for Bioethics.
Introducing the subject — and the book he has edited with the same title — Baer recalled his “horrible” early experience treating children with sickle cell anemia at Children’s Hospital in Los Angeles. “They were suffering. They had strokes,” he recalled. “And there was very little we could do.
“Now,” thanks to CRISPR, “we can cure sickle cell,” he said.
But should we? That remains the central issue for Baer, who also works as a screenwriter, dramatizing medical issues for TV shows such as “Designated Survivor” and “Law and Order: SVU.” (“I am Olivia Benson,” he told the audience, referring to the “Law and Order” protagonist).
With CRISPR technology, scientists can now edit both somatic genes (from the body) and germline genes (from gametes, the sex cells that form embryos), literally clipping out and replacing parts of them. In the case of sickle cell, manipulation of somatic cells can and has removed the genes underlying the disease in individuals. If such changes were made in germline cells, the resulting embryo would never develop the disease at all.
But while curing this painful disease may seem like an unalloyed positive, the questions around gene editing raise many troubling ethical questions. “Should we be using CRISPR for diseases or syndromes that are compatible with life, like Down syndrome?” asked Baer. “Who is going to make those decisions?”
The cost of gene manipulation is another factor. The sickle cell “cure,” for example, comes at a cost of roughly $2.2 million. Noting that approximately 100,000 people in the U.S. suffer from sickle cell, he asked, “Who is going to pay for it?” The domestic population, he continued, is only a fraction of the global sufferers, which raises issues of fairness and health equity.
Neal Baer (left) and Rebecca Brendel speaking during the event.
Citing this “cautionary tale,” Brendel became pragmatic. “The reality is that when we have innovation it makes those who have, have more, and those who don’t have, have less,” she said. “We can’t just innovate without thinking of the ethics. We have to think about the health justice implications as well.”
Even if curing sickle cell is considered a good, Baer argued, the changes made possible by this technology are troubling. For example, what if two deaf parents want their child genetically modified to be able to hear? “Should parents make that decision for their child? Is it up to parents to decide what attributes their children should have?”
In one of the book’s chapters, contributor Ethan J. Weiss divulged that had he and his wife known of their daughter’s albinism, “We would have aborted. But now that we have her, we can’t think of the world without her.”
Baer went on to quote Carol Padden, dean of social sciences at the University of California, San Diego, who was born deaf. “I don’t have a pathology,” she has said. “I have something called human variation. I don’t need to be ‘fixed.’”
Another concern is oversight. “Yes, it is illegal to clone. Yes, it’s illegal to do germline editing. But who is monitoring in Russia?” Baer asked. “Or China?” As if taking a page from a TV drama script, he discussed the possibilities of soldiers genetically altered to feel less pain, fear, or fatigue.
Additionally, Baer pointed out, gene editing may have unintended consequences. He cited a recent advance by the doctor and pharmaceutical company executive Sekar Kathiresan that allowed him to edit the gene controlling LDL cholesterol. While permanently lowering “bad” cholesterol, which is implicated in heart disease and strokes, sounds like a “win,” said Baer, the science isn’t that simple. “This gene evolved over 3 billion years and is involved in dozens and dozens of other” reactions, he said, including those involving insulin and other factors.
“Genes don’t just pop out,” he said. “They evolve and interact and do many different things.”
Mia, a young bonobo female, vocalizes in response to distant group membersMartin Surbeck/Kokolopori Bonobo Research Project
Science & Tech
Turns out, bonobos ‘talk’ a lot like humans
Researchers compile dictionary of vocalizations suggesting the animals use equivalent of word compounds, phrasings to communicate complex social situations
Clea Simon
Harvard Correspondent
April 28, 2025
4 min read
Researchers compile dictionary of vocalizations suggesting the animals use equivalent of word compounds, phrasings to communicate complex social situations
Clea Simon
Harvard Correspondent
4 min read
How old is language? A new study from researchers at the University of Zurich and Harvard University reveals that bonobos, our closest living relatives alongside chimpanzees, use the equivalent of word compounds and phrasings, suggesting that the roots of language predate humans.
Communication has always been about more than just words, say the researchers, Assistant Professor Martin Surbeck of Harvard’s Department of Human Evolutionary Biology, and Professor Simon William Townsend and postdoc Melissa Berthet, both at the University of Zurich. The way we pair words to make phrases and sentences and then link these parts into phrases and sentences defines language, and our ability to communicate with each other.
This capability — known as “compositionality” — lets us create new words and phrases. For example, a “bad dancer” is not necessarily “bad” in any absolute sense. That modifier links with “dancer” to create an easily understandable neologism. Such phrasings can help communicate complex social situations.
“There’s been a long-held evolutionary relationship between vocal complexity and social complexity,” said Townsend. Humans are proof of that. “Arguably humans have the most complex social organization, and we also have the most complex communication system with the most complex forms of ‘combinator’ reality.”
‘A complex communication system’
A bonobo whistling in the forest, to coordinate group movements over larger distances.
A bonobo emits a subtle peep before the whistle, to denote tensed social situations.
The study details the researchers’ observations of the vocal behavior of wild bonobos, a key species for reconstructing human evolution, in the Kokolopori reserve in the Democratic Republic of Congo. Using novel methods borrowed from human linguistics, the team demonstrated for the first time that bonobo vocal communication also relies extensively on compositionality.
Like humans, bonobos have complex social bonds. For example, their social group sometimes breaks off into smaller groups before coming together again. “The social organization is perhaps possible because of this more sophisticated communication,” said Berthet, lead author of the study.
The data collection, done over eight months, was painstaking. Researchers began with a list of roughly 300 contextual features to check off when a bonobo made a sound classified as a peep, yelp, or whistle, and “what they were doing or what was happening.” These assumed that a call could give an order — such as, “Run!” — announce an upcoming action (“I will travel”), express an interior state (“I am afraid”), or refer to an external event (“There is a predator”). The team recorded what happened for two minutes after each vocalization to see how that vocalization influenced the group.
Not only did various vocalizations link to various acts or occurrences, but strings of vocalizations revealed their own meanings, allowing the team to create “a dictionary of sorts,” said Berthet. This dictionary revealed how many of the call combinations had the compositionality recognized from human languages. “This dictionary represents an important step in understanding animal communication, as it is the first time researchers have systematically determined the meaning of all the calls of an animal,” Berthet wrote.
Olive, a first time bonobo mother, vocalizing toward distant group members.
Lukas Bierhoff/Kokolopori Bonobo Research Project
“The beauty of this approach is that all of a sudden we have something that allows us to quantify these aspects of the vocal repertoire in all different types of species,” said Surbeck. “It opens a new understanding into animal communication.”
Such structured language is not unique to humans and bonobos: Similar combinations have been observed in chimpanzees. However, that research has tended to focus on single-call combinations, while this new study looked at an entire vocal repertoire.
“It does seem to be the case that at least in chimpanzees and now bonobos, these species that are characterized by this quite complex social system and long-term social bonds between individuals, that you do start to see levels of combinatorial complexity that you might not see in species with less complex social systems,” said Townsend. This suggests that species “evolve a complex communication system so that you can keep the social bonds and the social relationships going at a distance.”
Because humans and bonobos share a common ancestor from approximately 7 million to 13 million years ago, said Surbeck, they share many traits by descent. “It appears that compositionality is likely one of them.”
Science & Tech
He got the stop-work order. Then the scrambling began.
Niles Singer/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
April 25, 2025
5 min read
Wyss’ Don Ingber details rush to hold onto consequential projects, talented researchers — and system that has driven American innovation
It was just hours after Harvard rejected the Trump administration’s demands th
He got the stop-work order. Then the scrambling began.
Niles Singer/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
5 min read
Wyss’ Don Ingber details rush to hold onto consequential projects, talented researchers — and system that has driven American innovation
It was just hours after Harvard rejected the Trump administration’s demands that the stop-work order arrived in Don Ingber’s inbox.
Ingber, the Wyss Institute for Biologically Inspired Engineering’s founding director, said the April 14 order targeted two of his organ-on-a-chip projects, which together had more than $19 million in multiyear contracts with a unit of the U.S. Department of Health and Human Services.
The move came in response to Harvard’s rejection of demands that included changes in governance, hiring and admissions, and audits of student, faculty, and staff opinions. A week later, Harvard filed a lawsuit, calling the demands an illegal and unconstitutional overreach and asking for funding to be restored.
After Ingber received the order, work halted but the scrambling — and uncertainty — began for everyone with a direct stake in the projects, including researchers, students, and postdoctoral fellows, he said.
With Harvard and the federal government at odds, with lawsuits filed, and after watching the Trump administration take dramatic steps in other areas only to walk them back, Ingber said he is reluctant to do anything permanent like layoffs.
“This is a stop-work order that could end next week, especially with the lawsuit going,” he said. “We’re going to take care of the people first. The projects need to stop in terms of expending funds, but if there’s spaces on other grants, we’re shifting people to them. We’ll try to find internal funds to keep them going at least until we figure out what’s going on.”
But decisions needed to be made quickly about how to wind down projects. Experiments halted midstream would likely be lost, as would the progress of students and postdoctoral fellows working on theses or papers based on those projects. There has also been a scramble to protect people, Ingber said, by finding places for them in other projects.
The research itself is also of consequence.
Ingber’s primary project uses organ-on-a-chip technology developed at the Wyss to investigate radiation damage to human lung, intestine, bone marrow, and lymph node, providing a tool to both model damage to tissues lining the chip’s tiny channels and identify new drugs that might ameliorate damaging effects.
Ingber said the research is particularly important given the administration’s plans to ramp up nuclear power production to support the energy-intensive artificial intelligence industry.
But even without AI, the project would be useful in modeling radiation damage to human organs in the event of an accident at a nuclear reactor, for cancer patients who undergo radiation therapy, and — in a worst-case scenario — a nuclear bomb explosion.
“What has driven the economy over the past 50 years is America’s innovation engine that fosters sciences which fuel technology development, driven by the pact between the government and academia.”
The second project uses organ-on-a-chip technology to model the effects of microgravity and radiation exposure on astronauts in spaceflight. Scheduled to be aboard the Artemis II mission to the moon, the specialized chips incorporate the astronauts’ own cells to investigate the impact of spaceflight on bone marrow — where blood cells arise.
“Once you get past the Earth’s atmosphere, solar flares generate incredibly high energy radiation that can be lethal,” Ingber said. “Astronauts will undoubtedly be exposed on a long flight to Mars and you can’t just put them up in a capsule made of lead, which is what some people might suggest, because weight is critical to getting out of the atmosphere. Unless we solve that problem, we’re not going to get to Mars with humans. Maybe robots, but not humans.”
The uncertainty is forcing hard decisions. Ingber said he’s already been approached by one scientist on his team who had immigrated to the U.S. and has decided to leave the Wyss to pursue work in Europe. Ingber agreed to give her a recommendation and help her find a suitable position.
“She’s only been here for six or eight months, but she’s terrified. They’re all terrified,” Ingber said. “It’s hard to know what to tell them, other than we’re going to protect them as much as we can.”
It has also affected the decisions of scientists to come to Boston. A European postdoctoral scientist who had accepted a position at the Wyss recently withdrew his acceptance, saying he had been warned by family and friends it’s not safe to be a foreigner in the U.S.
“We’ve been the magnet for the best and brightest around the world. It’s a positive-feedback loop. They really do attract others, build new industries, and become tax-paying Americans,” Ingber said. “Now, no one from America is going to go into science with its lack of stability, and we already have people in Europe turning down job offers.”
Ingber is baffled at what positive outcome the administration hopes to achieve. He spent 90 percent of his time over the last week managing the crisis: meeting with his leadership team, researchers, and staff; consulting with University administrators; and figuring out where funding can be found to meet rapidly shifting priorities.
He’s also writing op-eds about cuts at the NIH, FDA, and CDC and talking to the media in an attempt to make the broader point that academic research is the foundation of America’s innovation economy and underlies many of the things we accept as part of everyday life, from computers to optical cables to iPhones.
“What has driven the economy over the past 50 years is America’s innovation engine that fosters sciences which fuel technology development, driven by the pact between the government and academia,” he said. “This seems to be coming to an end.”
Work & Economy
Stantcheva awarded Clark Medal
Lawrence Katz, Elisabeth Allison Professor of Economics (left), during a celebration honoring Stefanie Stantcheva, winner of John Bates Clark Medal.Photos by Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
April 25, 2025
2 min read
Honored as a leading under-40 economist for pioneering insights on tax policy, innovation, be
Lawrence Katz, Elisabeth Allison Professor of Economics (left), during a celebration honoring Stefanie Stantcheva, winner of John Bates Clark Medal.
Photos by Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
2 min read
Honored as a leading under-40 economist for pioneering insights on tax policy, innovation, behavior
Harvard’s Stefanie Stantcheva has been awarded the American Economic Association’s 2025 John Bates Clark Medal, an annual prize recognizing an under-40 economist for significant contributions to the field.
“I’m incredibly honored, truly humbled, and very grateful for this award,” Stantcheva, the Nathaniel Ropes Professor of Political Economy, said Tuesday during a department celebration with colleagues and students.
In announcing the award, the association praised Stantcheva for exploring questions in public finance and producing new insights on tax policy and its impact on economic behavior.
Stefanie Stantcheva (left) and FAS Dean Hopi Hoekstra.
“The tax system is something so powerful that can essentially make or break an economy,” Stantcheva said. “It can either encourage things like innovation — if it’s properly designed — or really discourage economic activity.”
In their 2022 paper, “Taxation and Innovation in the 20th Century,” Stantcheva and her co-authors found that innovation responds to changes in tax policy with high elasticity. The study also revealed that higher taxes have a negative effect on the quantity of innovation but not the quality of inventions.
“Stefanie’s important contributions to the field make her so deserving of this award,” said Hopi Hoekstra, Edgerley Family Dean of the Faculty of Arts and Sciences. “It’s wonderful to celebrate her alongside her colleagues, including several past winners, which speaks to the continued strength of this department.”
“We’ve been extremely lucky this year, but not surprised at all that Stefanie got it,” said Elie Tamer, Louis Berkman Professor of Economics and chair of the Economics Department. “She has done stellar work and we’re very proud. It’s a happy day for Harvard and Harvard economics in particular.”
Stantcheva founded the Social Economics Lab in 2018. Her recent work has tackled issues in trade, immigration, climate change, and social mobility.
“I am excited to continue the work at the Social Economics Lab to better understand how people think about economic issues and policies,” Stantcheva said. “We are currently exploring new topics — such as the interplay between emotions and policy — and key mindsets, such as zero-sum thinking.”
Health
Bile imbalance linked to liver cancer
Heather Denny
HSDM Communications
April 25, 2025
3 min read
Key molecular switch identified, sheds new light on treatment interventions
A new study reveals how a critical imbalance in bile acids — the substances made by the liver that help digest fats — can trigger liver diseases, including hepatocellular carcinoma (HCC), the most common form
Key molecular switch identified, sheds new light on treatment interventions
A new study reveals how a critical imbalance in bile acids — the substances made by the liver that help digest fats — can trigger liver diseases, including hepatocellular carcinoma (HCC), the most common form of liver cancer. By identifying a key molecular switch that regulates bile, the study sheds new light on potential liver cancer treatment.
A unique function of the liver is to produce bile, which in turn acts as a natural detergent, breaking down fats into smaller droplets which are more readily absorbed by the cells in the lining of the small intestine. Beyond acting as a detergent, bile acids — a major component of the bile — also play a hormone-like function that governs a number of metabolic processes. Corresponding author of the study, Yingzi Yang, professor of developmental biology at the Harvard School of Dental Medicine, looked at the delicate control of how bile acids are produced and how disruption of the tight regulation leads to liver injury, inflammation, and eventually HCC.
Yang and her team at HSDM have spent years studying cell signaling. One of the pathways they focus on is the Hippo/YAP pathway — a signaling pathway crucial for regulating cell growth related to cancer.
Yingzi Yang.
Photo by Tony Rinaldo
“In this study we discovered that YAP promotes tumor formation with a surprising role in regulating bile acid metabolism. Instead of encouraging cell growth as expected, YAP acts as a repressor, interfering with the function of a vital bile acid sensor called FXR,” she said.
YAP activation paralyzes FXR (Farnesoid X receptor), a nuclear receptor essential to bile acid homeostasis. This causes an overproduction of bile acids that build up in the liver, leading to fibrosis and inflammation, ultimately leading to liver cancer.
Blocking YAP’s repressor activity — either by enhancing FXR function or promoting bile acid excretion — could stop this damaging cycle, according to researchers. In experimental models, activating FXR, inhibiting HDAC1 that enables YAP repressor function, or increasing the expression of a bile acid export protein (BSEP), all helped reduce liver damage and cancer progression.
“With this finding, it could lead us to pharmacological solutions that stimulate FXR, which is very exciting” Yang said.
According to Yang, the findings have additional implications as more is discovered about how YAP influences metabolic control by regulating nutrient sensing. Yang’s interest in studying this function came from her longtime work in cell signaling in liver biology and cancer. She is also a member of the Dana-Farber/Harvard Cancer Center.
The Yang Laboratory uses molecular, cellular, genetic, and genomic approaches to investigate the critical roles of cell signaling in embryonic morphogenesis and adult physiology. Their research focuses on the mammalian skeleton and liver to explore human biology and address the underlying pathophysiological mechanisms of diseases, including cancer.
This work was supported in part by the National Institutes of Health and the National Cancer Institute.
Health
FDA-approved smoking cessation pill helps break vaping habit
Clinical trial shows teens and young adults had three times more success quitting than their placebo counterparts
Isabella Davis
Mass General Brigham Communications
April 25, 2025
3 min read
Teens and young adults who took varenicline — an FDA-approved, twice-daily smoking cessation pill for adults — are more than three
Clinical trial shows teens and young adults had three times more success quitting than their placebo counterparts
Isabella Davis
Mass General Brigham Communications
3 min read
Teens and young adults who took varenicline — an FDA-approved, twice-daily smoking cessation pill for adults — are more than three times as likely to successfully quit vaping compared to those who received only behavioral counseling, according to a new study from Harvard-affiliated Mass General Brigham. Results are published in JAMA.
“Vaping is extremely popular among kids, and we know that this early nicotine exposure can make drugs like cocaine more addictive down the line, yet ours is the first treatment study to look at this vulnerable population,” said lead author A. Eden Evins, director of the Center for Addiction Medicine at Massachusetts General Hospital and the William Cox Family Professor of Psychiatry in the Field of Addiction Medicine at Harvard Medical School. “We wanted to help teens and young adults quit, and we found that prescribing varenicline is the best way to do that.”
According to investigators, about a quarter of 18-to-25-year-olds vaped in 2023, and roughly 8 percent of high schoolers vaped in 2024. Vapes have become a popular alternative to cigarettes with the added challenge of being easy to conceal and easy to use in public places. Yet they contain many of the same familiar health threats, like nicotine addiction, carcinogen and heavy metal exposure, and pulmonary inflammation. Exploring treatment plans is crucial to provide teens and young adults with safe, effective avenues to quit.
Because varenicline is already approved for smoking cessation in adults, it can be prescribed for anyone aged 16 to 25 wanting to quit nicotine vaping.
To identify such a treatment avenue, the Mass General Brigham team recruited 261 participants aged 16 to 25 into a randomized clinical trial. Participants were sorted into three treatment groups. The first was varenicline, weekly behavioral counseling, and access to a free text support service called “This is Quitting.” The second was placebo pills, weekly behavioral counseling, and the text service. The third was the text service alone. Each group was treated for 12 weeks, then checked on monthly for another 12 weeks post-treatment.
Each week, participants reported whether they had successfully quit vaping, and their responses were verified with cotinine saliva tests. At the end of 12 weeks of treatment and at three-month follow-up, the varenicline group had the highest quitting success rate. At 12 weeks, 51 percent of varenicline users had stopped vaping, compared to 14 percent of placebo users and 6 percent of text-only users. At 24 weeks, 28 percent of varenicline users had stopped vaping, compared to 7 percent of placebo users and 4 percent of text-only users.
These findings demonstrate the importance of medication to help young people who are addicted to nicotine quit vaping, since the varenicline group had three times more success quitting vaping than their placebo counterparts — despite both engaging in behavioral therapy. Further research is needed to explore the potential impact of other therapeutic approaches, as well as to look at even younger people who use nicotine vapes.
Because varenicline is already approved for smoking cessation in adults, it can be prescribed for anyone aged 16 to 25 wanting to quit nicotine vaping.
“Not only was varenicline effective in this age group — it was safe. Crucially, we didn’t see any participants that quit vaping turn to cigarettes,” said Randi Schuster, founding director of the Center for School Behavioral Health at MGH and associate professor of psychology in the Department of Psychiatry, HMS. “Our findings illustrate the effectiveness and safety of this therapy to address the urgent public health concern of adolescents addicted to nicotine because of vapes.”
This study was funded by the National Institutes of Health.
Zoe Marks (from left), Mai Hassan, Alex de Waal, and David Miliband. Niles Singer/Harvard Staff Photographer
Nation & World
New, bigger humanitarian crisis in Darfur. But this time, no global outcry.
Regional specialists sound alarm, say displacement, starvation affect many more than two decades ago.
Liz Mineo
Harvard Staff Writer
April 24, 2025
5 min read
Between 2003 and 2005, Sudan
New, bigger humanitarian crisis in Darfur. But this time, no global outcry.
Regional specialists sound alarm, say displacement, starvation affect many more than two decades ago.
Liz Mineo
Harvard Staff Writer
5 min read
Between 2003 and 2005, Sudan’s Darfur region captured the world’s attention as the government, amid a civil conflict, carried out a campaign of mass killing against an estimated tens of thousands of ethnic Darfuri.
Nearly 20 years later, the country has plunged into another civil war that has led to the world’s largest humanitarian crisis, with around 25 million people, half of Sudan’s population, experiencing acute hunger and 12 million displaced from their homes, according to the U.N.’s World Food Program.
But this time, the international community is not paying attention, decried experts on Sudan during a panel on April 15, “Sudan in Crisis: A Civil War, Humanitarian Emergency, and the Consequences for a Nation and Region,” hosted by the JFK Jr. Forum’s Institute of Politics. The event was moderated by Zoe Marks, Oppenheimer Faculty Director of the Center for African Studies at Harvard.
“This is an awful crisis, and just not enough light has been shed on it,” said Mai Hassan, faculty director of MIT-Africa. “It’s an understatement to say Sudan is in crisis or that Sudan is under fire. Over 150,000 people have died in this conflict. More than 10 million have been displaced, and more than 10 million are facing dire levels of hunger or starvation.”
“It’s an understatement to say Sudan is in crisis or that Sudan is under fire.”
Mai Hassan, MIT-Africa
The two-year ongoing conflict between the Sudanese Armed Forces (SAF) and the paramilitary Rapid Support Forces (RSF) has claimed the lives of 150,000 people and shows no signs of winding down. Hamid El-Bashir, a development expert originally from Sudan who participated remotely from Washington, D.C., lamented the international community’s apathy and indifference.
“When you look at the international response to the crisis in Sudan, there is no response,” said El-Bashir. “I attended the General Assembly a few months ago, and I came out with this conclusion: Sudan is going to collapse … There is no attention to this country.”
Twenty years ago, the global advocacy movement “Save Darfur” mobilized a worldwide response to condemn the atrocities and spearhead peace efforts in the region. In 2004, the U.S. government accused the government of Sudan and pro-government Arab militias before the U.N. Security Council of committing genocide.
Alex de Waal, executive director of the World Peace Foundation, recalled a visit he made then to Harvard to talk about the Darfur genocide, which became the first genocide of the 21st century.
“I remember being in this forum 20 years ago,” said de Waal. “There was a really vibrant movement on this campus, and other campuses, saying, ‘Save Darfur’ and ‘Never Again’ to genocide. What has happened to that passion, that commitment? And the celebrities who were so active then. They’re all silent now.”
Located in northeast Africa, Sudan is among the continent’s largest countries and boasts a strategic location bordering Egypt to the north and the Red Sea to the east. Sudan’s civil war has spilled over the region, with thousands of refugees having fled to South Sudan, Chad, and Egypt. The conflict is being fueled by regional powers supporting Sudan’s warring factions, which could further destabilize the region, said David Miliband, president and CEO of the International Rescue Committee.
“It’s not as simple as a unified SAF and a unified SAF force, both of which came out of the Sudanese armed forces,” said Miliband. “There is a constellation of forces supporting each side. The United Arab Emirates, the kingdom of Saudi Arabia, Turkey, Russia, Iran, Egypt are all in there supporting different sides, and they’re supporting them sufficiently that both sides think that they can win, and that there’s no reason to stop.”
One student asked for suggestions on how to rally international support to stop the civil war. The panelists highlighted the need to support humanitarian aid, start a widespread movement to demand a ceasefire, and begin a peace process that involves civilians, the United Nations, and Middle Eastern powers.
There needs to be pressure on the regional powers that are fueling the conflict, too, said Miliband, but the first step is to provide humanitarian aid. A community-led initiative formed in Sudan in 2019, the Emergency Response Rooms has sprung into action since the conflict started.
“First of all, you’ve got to stop things getting worse,” said Miliband. “Stopping the slide is very important. I always say humanitarian aid is the first step on the road to development. Unless you can stop things from getting worse, unless you stop the bleeding, we’re going to lose more people, and every bloodshed leads to further danger.”
For MIT-Africa’s Hassan, the situation is dire and requires international action. She remains hopeful that Sudanese civil society will rise up again despite the challenges.
“What’s awful about the situation, not only the actual empirics of it, but that it comes on the heels of a euphoric popular revolution that overthrew a despised Islamist regime,” said Hassan, referring to the 2019 military coup, which took place after a year of massive protests that deposed dictator Omar al-Bashir, who was in power for 30 years.
“I’m hopeful that civil society will be mobilized again in some fashion to help bring some kind of legitimacy to whatever new state emerges or when a peaceful resolution comes about,” said Hassan. “It’s going to involve a popular mobilization. I think civil society can be mobilized again.”
Arts & Culture
Future doesn’t have to be dystopian, says Ruha Benjamin
Veasey Conway/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
April 24, 2025
3 min read
In Tanner Lectures, Princeton sociologist talks AI, social justice
The average citizen shouldn’t be afraid to imagine a radically different future for humanity, Ruha Benjamin argues. After all, the billionaire CE
Future doesn’t have to be dystopian, says Ruha Benjamin
Veasey Conway/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
3 min read
In Tanner Lectures, Princeton sociologist talks AI, social justice
The average citizen shouldn’t be afraid to imagine a radically different future for humanity, Ruha Benjamin argues. After all, the billionaire CEOs of tech companies are doing it.
The professor of African American Studies at Princeton University, who delivered the Tanner Lectures on Human Values hosted by the Mahindra Humanities Center last week, argued that proponents of AI-powered futures often frame their visions as altruistic despite actually being driven by self-interest.
“There’s absolutely no reason to trust that tech elites have any wisdom to offer when it comes to alleviating human suffering,” Benjamin told the audience who packed Paine Hall. “Billionaires building bunkers to survive AI apocalypse, attempting to disrupt death through cryopreservation, scouting the planet for pop-up cities and network states, are not reliable stewards of the collective good.”
Too often AI technologies marketed as “efficient” and “progressive” only create more oppression, Benjamin said, citing examples such as facial recognition software leading to false arrests and automated triage systems deciding who receives healthcare.
Benjamin said AI is often touted as a moral (or, at least, morally neutral) decision-making technology because it operates on math rather than emotion. But making decisions for society based on math and algorithms hurts the same marginalized groups harmed by the 20th-century eugenics movement, she said.
“One of the buzzwords that goes around is that these systems are so special because they’re engaged in ‘deep learning,’ by which people mean computational depth,” Benjamin said. “But what I suggest is that computational depth without social and historical depth ain’t that deep.”
Benjamin said it’s hypocritical to see superintelligence, Mars colonies, and underground apocalypse bunkers as bold innovations while viewing public goods such as free public transportation and affordable housing as impractical.
“This is an invitation to think about the different types of knowledges that we need around the table,” Benjamin said. “We can’t leave it simply to those who have technical know-how. Many of the problems we’re enduring right now are because those people who are creating tech solutions for society don’t know anything about society.”
Benjamin called for a renewed focus on creativity and imagination, urging universities to prioritize inquiry through arts and humanities.
“This is an invitation not only to be critical, but to be creative. To ask ourselves, ‘Now what?’” she said. “Instead of trying to make the world a little less harmful and make these systems a little less harmful, what if we were to completely reimagine them, envisioning a world beyond borders, beyond policing, beyond surveillance and supremacy? In the process, I think we’ll have to work on dismantling the walls in our own minds, those mental barriers that tell us to ‘get real’ when we attempt to imagine otherwise.”
Health
U.S. pregnancy-related deaths continuing to rise
Study researcher says nation, which leads high-income peers in maternal mortality, needs better prenatal, extended postpartum care
Anna Gibbs
Harvard Correspondent
April 23, 2025
7 min read
In the U.S., more than 80 percent of pregnancy-related deaths are preventable. Yet for many years, the nation has had the highest maternal morta
Study researcher says nation, which leads high-income peers in maternal mortality, needs better prenatal, extended postpartum care
Anna Gibbs
Harvard Correspondent
7 min read
In the U.S., more than 80 percent of pregnancy-related deaths are preventable. Yet for many years, the nation has had the highest maternal mortality rate among high-income countries. And that rate continued to rise between 2018 and 2022, with large disparities by state, race, and ethnicity, a new study reports.
A team of researchers at the National Institutes of Health, in collaboration with Associate Professor Rose Molina of Harvard Medical School, used data from the Centers for Disease Control and Prevention to study pregnancy-related deaths in that four-year period.
The sharpest rate increase occurred in 2021, likely reflecting the onset of the COVID-19 pandemic in 2020. While the rates then lowered, they were still higher in 2022 (32.6 deaths per 100,00 live births) than they were in 2018 (25.3 deaths per 100,000 live births).
The results were consistent with past research that has demonstrated significant disparities across racial groups. American Indian and Alaska Native women had the highest mortality rate (106.3 deaths per 100,000 live births), nearly four times higher than the rate among white women (27.6 deaths per 100,000 live births), followed by non-Hispanic Black women (76.9 deaths per 100,00 live births).
State rates also varied greatly, ranging from 18.5 to 59.7 deaths per 100,000 live births.
In this edited conversation, Molina, an obstetrician-gynecologist, discusses the findings and what needs to happen next.
Why is pregnancy-related death much higher in the U.S. than other high-income countries?
“There are many reasons: our patchwork healthcare system, inequitable policies, maternity care deserts, as well as persistent systems of bias and discrimination across racial and ethnic groups.”
There are many reasons: our patchwork healthcare system, inequitable policies, maternity care deserts, as well as persistent systems of bias and discrimination across racial and ethnic groups. It’s the way in which the healthcare system is designed. There are also signals that reproductive-age individuals are experiencing more chronic medical conditions, including cardiovascular disease, at younger ages than before.
The results showed some significant racial disparities in maternal mortality rates. Was that surprising?
While I am saddened that the racial inequities have persisted, the reality is that this has been demonstrated over and over again in the literature. There have been some innovations aimed at reducing inequities between racial groups in health systems. But at a population level, as a country, we’re not seeing meaningful improvement yet.
Our study points to different policy levers that need to be addressed, because there shouldn’t be as much state-level variation as there is. One of our biggest findings is that we could have avoided 2,679 pregnancy-related deaths during this time period if the national rate were that of California. If California can do it, then how can we get other states to perform as well?
The overall leading cause of death in your study was cardiovascular disease, which accounted for just over 20 percent of deaths. Has that always been the case?
Over the decades in the U.S., we’ve seen a transition from hemorrhage to cardiovascular disease as the leading cause of pregnancy-related death. Cardiovascular disease encompasses a range of disorders: hypertension, pre-eclampsia, eclampsia, and peripartum cardiomyopathy, cardiac arrest, and stroke.
One reason for the shift may be that more and more people have chronic hypertension. We saw that the highest increased rate of pregnancy-related death was actually in the middle-age group (those 25 to 39), not the highest-age group. Therefore, one of the potential concerns is that chronic diseases like hypertension are affecting younger people. It’s been much more common to have hypertension if you’re 40 or older. But we’re beginning to see more hypertension at an earlier age.
“We saw that the highest increased rate of pregnancy-related death was actually in the middle-age group (those 25 to 39), not the highest-age group. Therefore, one of the potential concerns is that chronic diseases like hypertension are affecting younger people.”
In fact, pregnancy-related death increased for all age groups between 2018 and 2022. How significant is that rise?
It’s only four years, and the studied time period spanned the initial part of the COVID pandemic. But there’s still enough evidence that we should be paying more attention to this increase. Even in 2022, the rates were higher than in 2018. And the rates were already rising in 2019, before the pandemic started.
You also found that “late maternal deaths” — those that occur between 42 days and 1 year after pregnancy — accounted for nearly a third of the total. Yet the World Health Organization does not include late maternal death in its definition of pregnancy-related mortality. Why is it important to consider this time period?
Internationally, any death during pregnancy and up to 42 days after birth is considered a maternal mortality. In the U.S., we’re moving toward being inclusive of the full year after birth, because the 42 days postpartum is somewhat arbitrary.
There’s a growing recognition that the postpartum period doesn’t just end on a cliff at six weeks, even though that’s how many of our healthcare systems are designed, but rather postpartum recovery should be treated as a continuum. The high number of late maternal deaths points to why we need to design better systems of healthcare in those later months, as opposed to only focusing on the first six to 12 weeks.
Rose Molina.
Veasey Conway/Harvard Staff Photographer
This study offers a fuller picture of the problem than past tallies. Can you talk a bit about that?
One of the biggest challenges in tracking maternal deaths in the United States is that we didn’t actually have a national system for tracking these deaths consistently until 2018, because that’s when the full implementation of the pregnancy checkbox on death certificates went into full effect across the 50 states.
What that means is that when someone dies, the death certificate now has a pregnancy check box, so there can be some indication as to whether the person who passed away was pregnant at the time. However, it took a long time for all states to fully implement that. That’s why our data is so interesting, because we looked at the data starting in 2018, when that process was fully implemented across the 50 states.
“The biggest take-home message is that we need to continue to invest in public health infrastructure. It’s very clear that we’re not getting better, and if anything, the rates of pregnancy-related deaths are getting worse.”
Now that everything is laid out, how can these numbers be improved? What needs to happen next?
The biggest take-home message is that we need to continue to invest in public health infrastructure. It’s very clear that we’re not getting better, and if anything, the rates of pregnancy-related deaths are getting worse. So we need to change something about how we are addressing this.
In particular, we need to increase investment in innovative solutions to address quality of care during pregnancy and the extended postpartum period. At the state level, we really need to be addressing policy differences and trying to understand why certain states fare so much worse than other states.
It’s a concerning moment because the public health infrastructure to track these deaths is at risk. Research dollars are being cut dramatically. Pregnancy is being deprioritized. These actions and cuts threaten any work trying to improve maternal health outcomes, which can help inform policy at the state level and advocacy to enhance access to quality full-spectrum pregnancy care.
Veasey Conway/Harvard Staff Photographer
Health
Rewriting genetic destiny
David Liu, Breakthrough Prize recipient, retraces path to an ‘incredibly exciting’ disease fighter: ‘This is the essence of basic science.’
Sy Boles
Harvard Staff Writer
April 23, 2025
5 min read
Part of the
Profiles of Progress
series
In 2022, Alyssa Tapley was 13, suffe
In 2022, Alyssa Tapley was 13, suffering from T-cell leukemia, and facing a grim prognosis after existing treatments failed to improve her condition. Then, a clinical trial using a novel gene-editing technology called base editing cleared her cancer. It was a breakthrough for science — Tapley’s therapy was the first enabled by base editing — and a lifeline for the patient.
“Now, 2½ years later, I’m 16, preparing for exams, spending time with my family, arguing with my brother, and doing all the things I thought I’d never be able to do,” Tapley told the audience at the 2025 Breakthrough Prize ceremony on April 5. The prizes, whose recipients this year included several Harvard researchers, honor achievements in physics, life sciences, and mathematics.
The scientist behind the technology that saved Tapley’s life is David Liu, the Dudley Cabot Professor of the Natural Sciences and vice chair of the faculty at the Broad Institute of MIT and Harvard.
“It’s incredibly exciting, and also comes with a heavy sense of responsibility, to make sure that — to the extent humanly possible — we have done everything we can to make these agents as safe and effective as possible for use in patients,” Liu said.
Hundreds of millions of people worldwide suffer from genetic diseases. To help them, Liu, with support from the NIH, DARPA, and other federal agencies, has built on and looked beyond CRISPR-Cas9, the transformative gene-editing protein found in bacteria that cuts through DNA like scissors.
“That approach of cutting the DNA double helix is very useful for gene disruption or deletion,” he said. “But if your goal is to correct a mutation that causes a genetic disease, it’s not easy to use scissors to achieve gene correction.”
The limits of the “scissors” approach led Liu and his team, including former postdocs Alexis Komor and Nicole Gaudelli, to develop two new approaches to gene editing: base editing and prime editing. Base editing works on the four nucleotide bases of a DNA strand — A, C, G, and T — rather than on the entire double helix.
“You can change a C to a T, a T to a C, an A to a G, or a G to an A,” Liu said. “And those happen to be four of the most common kinds of mutations that cause genetic diseases.”
But what about genetic diseases caused by other kinds of single-letter swaps, or by unwanted extra letters, or by missing DNA letters? For those cases, Liu’s team, including former postdoc Andrew Anzalone, developed prime editors. Liu likened the tool to a word processor, able to search out a flawed piece of DNA and replace it with a synthesized DNA flap that is specified by the user.
“There was no knowledge of what CRISPR did, or whether it was going to be useful. But it was interesting enough for curious people to study.”
As of today, there are at least 18 clinical trials using base editing or prime editing to treat a range of diseases, with dozens of patients already treated, Liu said.
Liu connects his research to basic science — research that seeks to understand something new about the world without a clear application in mind — that began at Japan’s Osaka University in 1987. There, a team of researchers noticed something unusual in DNA from E. coli bacteria: highly repetitive DNA sequences that were interspersed with non-repetitive sequences, but with the exact same spacing. The phenomenon became known as Clustered Regularly Interspaced Short Palindromic Repeats, or CRISPR.
“There was no knowledge of what CRISPR did, or whether it was going to be useful,” Liu said. “But it was interesting enough for curious people to study. This is the essence of basic science.”
Over the course of decades, researchers learned that CRISPR was a kind of immune system that bacteria use to protect themselves from viruses. When a virus enters a bacterial cell, the bacterium incorporates some of the virus’s DNA as a kind of genetic memory, allowing it to identify and destroy the virus if it encounters it again.
“You can imagine a critic saying, ‘Why do I care about a bacteria’s ability to kill a virus?’” Liu said. “The answer is that it turned out to lead to all the CRISPR nuclease clinical trials, and eventually led to base editing and prime editing, and now we can make just about any kind of change in the DNA of living systems, including correcting the vast majority of mutations that lead to genetic disease. And it all came from the basic science of geneticists who first looked at these clustered regularly interspaced short palindromic repeats and wondered what they were doing.”
Liu is loath to call his technologies a cure: “Scientists are reluctant to use that word until there’s evidence of years without any apparent symptoms of the disease,” he said. But, he added, “The writing’s already on the wall: In some of these clinical trials, the patients are no longer on any medication and don’t have any symptoms of the disease.”
Looking to the future of research and innovation, Liu says he’s deeply worried about the current threat to the partnership between higher ed and the federal government, especially as it relates to young scientists.
“There’s a lot of fear and chaos now that is preventing young scientists from entering the phase of their careers where they can contribute to society in a direct way,” he said. “And that’s a very real tragedy.”
Gary Ruvkun in the 1990s.Harvard file photo
Science & Tech
Long trail from 1992 discovery to 2024 Nobel
Gary Ruvkun recounts years of research, which gradually drew interest, mostly fueled by NIH grants
Jacob Sweet
Harvard Staff Writer
April 22, 2025
4 min read
Part of the
Profiles of Progress
series
Gary Ruvkun and Victor Ambros were not k
Gary Ruvkun and Victor Ambros were not known as superstars in their field back in 1992 when they discovered microRNA, a feat that would earn them the 2024 Nobel Prize in physiology or medicine.
“We were fine. We weren’t terrible,” said Ruvkun, a professor of genetics at Harvard Medical School. “But there was nothing about it that made it seem like, ‘Oh, these guys are walking on water!’”
Even after the former Harvard collaborators published their findings in the journal Cell in 1993, revealing a new level of gene regulation in the C. elegans roundworm, the evolutionary biology community was not overly impressed. It wasn’t clear that the genes Ruvkun and Ambros, now a professor at the University of Massachusetts Chan Medical School, discovered mattered to other species, including humans.
Instead, their work, mostly funded by the National Institutes of Health, drew interest from a smaller group of RNA researchers and what Ruvkun calls the “worm community” — those interested in the same model organism.
Ruvkun speaks at the Medical School after winning the 2024 Nobel Prize in physiology or medicine for his role in the discovery of microRNA.
Harvard file photo
But the interest in the RNA field kept growing. Meetings that formerly would have drawn 100 attendees doubled in size within a few years. It became clear that the same tiny RNAs had the same role in plants and in worms, and scientists in all different fields were interested in the same questions.
Ruvkun started to realize, “This was some revolutionary stuff, and we were the only people thinking about tiny RNAs in the world.”
Decades of federally funded breakthroughs later, microRNAs are considered fundamental to how organisms develop, mature, and function — playing a key role in translating genes into proteins.
Studies have discovered that the human genome contains about 1,000 microRNAs that control most human protein-producing genes. Therapies based on microRNAs to treat heart disease, cancer, Crohn’s Disease, Alzheimer’s, and several other diseases are in clinical trials.
Ruvkun says about three-quarters of his lab research has been funded by the federal government for the past 40 years, at about $150,000 a year. The money provides enough support for about four people. “It’s not like I had a lab of 50,” he said.
He expresses puzzlement at calls to cut federal funding, emphasizing that spending on scientific work is far from wasteful. “The average pay of the people in my lab has always been about three times the minimum wage,” he said. “These are scientists, and they’re super educated. They have Ph.D.s or are getting Ph.D.s, but they’re paid a little better than working at Dunkin’ Donuts.”
Ruvkun is proud that basic research from his field has led to major pharmaceutical companies like Alnylam, which focuses on the discovery, development, and commercialization of RNA interference therapeutics for genetic diseases.
“It’s one of the 10 biggest companies in Massachusetts,” he said, “and it didn’t even exist 20 years ago.” He’s also glad that his research had enough of an impact that he can continue doing basic science while others worry about the business implications.
Of the top 500 companies in the country, Ruvkun emphasizes, well over half are driven by technology — much of the foundational research behind them driven by federal grants. He credits federal funding with turning the U.S. into a scientific and economic superpower during and after World War II.
He worries that a lack of investment could push members of his laboratory away from science research.
“I have all of these people who are 25, 30 years old, and they’re like, ‘What career do I have? What am I going to do?’” The answer, he said, might be the reverse of the post-war trend: They’ll leave the U.S. for more stable positions in Europe.
Campus & Community
Kareem Abdul-Jabbar named Class Day speaker
Kareem Abdul-JabbarPhoto by Dan Winters
Laura Speers
Harvard Correspondent
April 22, 2025
4 min read
NBA icon, award-winning author, and humanitarian chosen for ‘his lasting efforts to build a more just and compassionate world’
Part of the
Commencement 2025
series
A collection
A collection of features and profiles covering Harvard University’s 374th Commencement.
Legendary basketball player, writer, and activist Kareem Abdul-Jabbar will address the Harvard College Class of 2025 during the annual Class Day celebration on May 28, the day before Harvard’s 374th Commencement.
“We are so excited to welcome Kareem Abdul-Jabbar as the featured Class Day speaker,” said Uzma Issa ’25, first marshal of the 2025 Class Committee. “He’s a champion in every sense of the word — celebrated both for his extraordinary achievements on the court and his lasting efforts to build a more just and compassionate world. He has shown that true leadership is measured by the difference we make in people’s lives.”
“It’s a privilege to share this moment with the Class of 2025 and to celebrate all that lies ahead,” said Abdul-Jabbar. “The world needs their ideas, their energy, and their heart. I hope my words will encourage them to keep learning, keep growing, and keep showing up — for themselves and for others.”
Widely regarded as one of the greatest basketball players of all time, Abdul-Jabbar is also an award-winning author, cultural icon, and tireless advocate for social justice. In 2016, he received the Presidential Medal of Freedom — the nation’s highest civilian honor — in recognition of his contributions on and off the court.
The 7-foot-2 basketball Hall of Famer dominated the NBA for two decades with his trademark skyhook, becoming the league’s all-time leading scorer — a title he held for 39 years. A 19-time NBA All-Star and six-time NBA champion, he remains the only player in NBA history to win six Most Valuable Player awards. Time magazine once dubbed him “History’s Greatest Player.”
Since retiring in 1989, Abdul-Jabbar has continued to use his platform to challenge public thinking on a wide range of issues. An influential columnist, he has written for major media outlets worldwide and now publishes regularly on his Substack newsletter. A nine-time Southern California Journalism Awards Columnist of the Year, he is known for incisive commentary on sports, politics, and popular culture. Today, he remains one of the most outspoken and respected voices confronting racism and inequality in America.
Abdul-Jabbar traces his activism back to his high school years in Harlem, when he had the chance to ask Martin Luther King Jr. a question at a news conference. The brief exchange sparked a lifelong commitment to fighting injustice like systemic racism and inequality in education, health, and employment.
Appointed in 2012 as a U.S. Cultural Ambassador by the State Department, he was tasked with promoting education, racial tolerance, and cross-cultural understanding among young people around the world. In 2021, the NBA established the Kareem Abdul-Jabbar Social Justice Champion Award to honor the next generation of athletes working to lift up their communities. His public service efforts have earned him numerous honors, including Harvard’s W.E.B. Du Bois Medal in 2022.
Abdul-Jabbar is the founder and chair of The Skyhook Foundation, which brings science, technology, engineering, and mathematics education to underserved communities in Los Angeles.
An award-winning documentary producer and two-time Emmy-nominated narrator, Abdul-Jabbar is the subject one of HBO’s most-watched sports documentary of all time, “Kareem: Minority of One.” His on-screen appearances span hundreds of iconic film and television roles.
“Kareem Abdul-Jabbar has spent a lifetime speaking out against injustice and using his platform to educate and inspire,” said Srija Vem ’25, second marshal of the 2025 Class Committee. “As we prepare to take our next steps in life, his legacy reminds us that we all have the opportunity — and the responsibility — to use our voices, our intellect, and our talents in service of something greater.”
In addition to Abdul-Jabbar’s address, Class Day includes award presentations and student orations. The event will begin at 2 p.m. on May 28 in Tercentenary Theatre and will be livestreamed.
Campus & Community
Harvard files lawsuit against Trump administration
Photo by Grace DuVal
Alvin Powell
Harvard Staff Writer
April 21, 2025
5 min read
Filing argues freeze of research funding violates First Amendment, laws, procedures
Harvard filed a lawsuit Monday against the Trump administration, arguing its freeze on research funding is unconstitutional and “flatly unlawful” and c
Harvard files lawsuit against Trump administration
Photo by Grace DuVal
Alvin Powell
Harvard Staff Writer
5 min read
Filing argues freeze of research funding violates First Amendment, laws, procedures
Harvard filed a lawsuit Monday against the Trump administration, arguing its freeze on research funding is unconstitutional and “flatly unlawful” and calling on the court to restore more than $2.2 billion in research dollars.
The filing, in U.S. District Court in Boston, requests that the court vacate and set aside the funding freeze to allow previously approved funding to flow and halt administration efforts to freeze current or deny future funding without engaging in procedures contained in federal law.
In a message to the community Monday, President Alan Garber said the suit was prompted by steps the government took over the last week, after the University rejected administration demands for changes to Harvard’s governance, hiring, and admissions policies, and to ensure “viewpoint diversity” in part through audits of viewpoints of students, faculty, and staff.
Garber described those changes — contained in an April 11 letter from the government — as intrusive and said they’d impose “unprecedented and improper control over the University.”
Garber noted some Trump administration representatives have said since April 11 that the letter was sent by mistake. But he said other statements and the administration’s actions since don’t bear that out.
Within hours of Harvard’s rejection of White House demands, the administration doubled down by announcing a freeze of $2.2 billion in funding and has since said it is considering revoking Harvard’s tax-exempt status and threatening the education of international students. In addition, Garber said, the administration is considering freezing an additional $1 billion in funding.
“Moments ago, we filed a lawsuit to halt the funding freeze because it is unlawful and beyond the government’s authority,” Garber said. “Before taking punitive action, the law requires that the federal government engage with us about the ways we are fighting and will continue to fight antisemitism. Instead, the government’s April 11 demands seek to control whom we hire and what we teach.”
Harvard’s complaint says the First Amendment protects free speech against government interference intended to enforce ideological balance and bars the government from using legal sanctions or other coercion to suppress speech it doesn’t like.
The complaint also describes the government’s freeze-first strategy as violating laws that lay out procedures for research fund recipients suspected of civil rights violations. Prescribed steps progress from voluntary negotiations to an official hearing followed by findings. Then, only 30 days after the findings are released can funding be terminated.
“These fatal procedural shortcomings are compounded by the arbitrary and capricious nature of Defendants’ abrupt and indiscriminate decision,” the lawsuit said.
The filing describes a rapid escalation on the part of the government. After initial inquiries in February from the administration’s multi-agency Task Force to Combat Antisemitism, administration and University officials scheduled an official visit to campus in late April.
In late March, however, Harvard received a letter announcing a review of research grants totaling $8.7 billion to the University and its hospital affiliates. On April 3, Harvard received a list of conditions under which it might ensure continued funding and, finally, on April 11, a letter fleshed out those conditions.
Those details, which included overreaching and broad-ranging demands, prompted the University’s rejection and Garber’s statement that Harvard would not negotiate over either its independence or its constitutional rights.
Garber said the administration’s actions have jeopardized critical research being conducted on cancer, infectious disease, and battlefield injuries.
With funding in flux, the lawsuit says, hard decisions about things like living cell lines being used to investigate disease and the jobs of researchers whose positions are tied to federal grants will have to be made. Unless funding is restored, Harvard’s research programs will be considerably curtailed.
“The consequences of the government’s overreach will be severe and long-lasting,” Garber said. “Indiscriminately slashing medical, scientific, and technological research undermines the nation’s ability to save American lives, foster American success, and maintain America’s position as a global leader in innovation.”
Garber acknowledged that work to fight antisemitism remains to be done on campus. “We need to ensure that the University lives up to its ideals,” he said.
Though Harvard has already taken several steps in that direction, Garber said the Task Force on Combating Antisemitism and Anti-Israeli Bias and the Task Force on Combating Anti-Muslim, Anti-Arab, and Anti-Palestinian Bias will soon release full reports.
He described them as “hard-hitting and painful” and said they include recommendations that have concrete plans for implementation.
“As a Jew and an American, I know very well that there are valid concerns about rising antisemitism. To address it effectively requires understanding, intention, and vigilance,” Garber said. “Harvard takes that work seriously. We will continue to fight hate with the urgency it demands as we fully comply with our obligations under the law. That is not only our legal responsibility, it is our moral imperative.”
Nation & World
Freezing funding halts medical, engineering, and scientific research
Liz Mineo
Harvard Staff Writer
April 21, 2025
7 min read
Projects focus on issues from TB and chemotherapy to prolonged space travel, pandemic preparedness
The Trump administration’s decision to freeze more than $2 billion in long-term research grants to Harvard has put a halt to work across a wide r
Freezing funding halts medical, engineering, and scientific research
Liz Mineo
Harvard Staff Writer
7 min read
Projects focus on issues from TB and chemotherapy to prolonged space travel, pandemic preparedness
The Trump administration’s decision to freeze more than $2 billion in long-term research grants to Harvard has put a halt to work across a wide range of medical, engineering, and scientific fields. The action came in response to the rejection of White House demands for changes that the University argues infringes on its independence and constitutional rights and exceeds the administration’s lawful authority.
The NIH had earlier halted an estimated $110 million in grants to Harvard and its associated hospitals since late February.
We interviewed some of the researchers whose projects have been halted or face an uncertain future.
John LaPorte Given Professor of Immunology and Infectious Diseases, and chair of the Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health
Research interrupted: A $60 million seven-year, multi-institutional consortium to study how the immune system controls tuberculosis.
“About a third of the world is thought to be infected with TB and carry TB, and most of those people will not get sick. But every year, 10 million people get sick, and 1 million people die, which makes TB the world’s leading infectious cause of death. We’re trying to understand the difference between protective and failed immunity to TB to better identify people with TB and then prevent TB, ideally with an effective vaccine.
“This consortium was conceived of at the National Institutes of Health as their moonshot effort to move the needle on TB. The goal was to bring together the very best researchers from around the country and around the world to bring the very best cutting-edge technology, the very best science to understand TB immunity. And if it stops, the whole thing is gone.
“I’ve been building this consortium since about 2014. For me, this is over a decade of work. Scientific knowledge, scientific expertise is a craft. And if you blow it up, you can’t just rehire people and recreate it and then start again. It’s gone.”
[Open Philanthropy, a California-based philanthropic group, has authorized a $500,000 grant to allow researchers at the University of Pittsburgh School of Medicine to complete an ongoing tuberculosis vaccine study, The Boston Globe reported Monday. That study is a single piece of the broader project Fortune is working on as a principal investigator.]
Founding director of the Wyss Institute for Biologically Inspired Engineering at Harvard, Judah Folkman Professor of Vascular Biology at Harvard Medical Schooland the Vascular Biology Program at Boston Children’s Hospital, and Hansjörg Wyss Professor of Bioinspired Engineering, Harvard John A. Paulson School of Engineering and Applied Sciences
Research interrupted: Two contracts worth under $20 million: one to test and develop drugs to treat long-term radiation exposure, including chemotherapy, and the other to study the effects of microgravity and radiation in space on human cells to help astronauts travel to Mars.
“Both projects were contracts administered by the Biomedical Advanced Research and Development Authority (BARDA), which is responsible for developing countermeasures for biological, radiation, and chemical threats for the U.S.
“The larger BARDA contract focuses on development of human organ-on-a-chip microfluidic culture models of human lung, intestine, bone marrow, and lymph to model the human response to exposure to gamma radiation, and to identify potent radiation countermeasure drugs. We have made great progress on this project.
“The BARDA project supported by NASA is to use human organ-on-a-chip technology to create living ‘avatars’ of astronauts by lining the chips with cells from astronauts and then flying the chips alongside them on space missions. The goal is to use these to understand the effects of microgravity and radiation (which currently makes it impossible for man to go on long space flights, to Mars, for example) and again, develop countermeasures. This initial project is to demonstrate the feasibility of this approach.
“Radiation countermeasure drugs we are developing would be valuable for cancer patients, many of whom receive radiation therapy and experience side effects (higher and more effective therapeutic doses could be administered with less toxicity) as well as be stockpiled to protect against a nuclear disaster or attack; and they could enable long term spaceflight, and hence, exploration of Mars, which is not possible now.
“As for what the repercussions are, it means that this type of work would stop but more importantly that the salaries of almost 20 students, fellows, and staff are at risk if this stop order is not reversed soon.”
Associate professor of medicine, Harvard Medical School
Research in peril: A $10 million project grant to fund a large consortium of laboratories to study the immune system and its ability to respond to different coronaviruses as preparation for future possible pandemics. That grant was halted before the most recent freezes and later temporarily reinstated by a court order pending appeal.
“What we learn from coronaviruses is relevant to other infections because we’re trying to understand how the immune system operates.
“We were finishing up our third year of a five-year plan. The termination was a surprise.
“There are multiple levels of loss. On one level, these grants from the NIH are vetted very heavily by independent scientific review, and there’s only a small percentage of grants that end up getting funded because of the review process. Grants like this and others that are terminated, which have been vetted, scored, and deemed important, rigorous, and worthy to happen, represent a loss of all the effort that went into the process.
“For our lab, it is a huge loss of opportunity. We have been collecting longitudinal blood samples from several individuals over many years to try to understand the long-term effects of immunity to the virus, infection, as well as vaccination, to study how long-lasting things are, and what regulates the longevity of the immune response.
“We may have to cancel collecting blood from this cohort. To see this happen to our lab and to see it happen to other labs across the country is devastating.”
Assistant professor of medicine, Harvard Medical School
Research facing uncertainty: A $3.5 million neuroscience research project that studies how the neurons in the gut change with aging and conditions such as Parkinson’s and Alzheimer’s diseases.
“My research project has not been stopped yet. Whether it will be stopped or not is something that I don’t know.
“My project is based at my research lab, which is a neuroscience lab that studies the gut. We study the neurons that reside in the gut and regulate the human functions related to eating, digesting, and defecation.
“It is important to understand how these neurons change with aging or with conditions such as Parkinson disease, Alzheimer’s disease, or irritable bowel syndrome. What our lab does is try to understand how the neurons in our gut age, and what can we do to make them young again.
“This is an ongoing project. Our ability to keep on going depends upon our ability to keep putting in grants and getting in the money because we are at the end of our grant cycle. If our grants don’t get funded, all that research stops, and the years of work will go wasted. We are in the last year of a five-year grant. If the grant is curtailed even before the time ends, then the work will stop immediately.
“One of the main things to remember is that when we get funding, part of that goes toward salaries, but a significant part goes towards buying reagents and chemicals from American manufacturers and buying mice from American companies. Every single dollar of federal funding is spent toward people’s salaries and reagent materials that are here in the U.S.
“Our ability to train undergraduates, who are American, all stops immediately if our funding gets stopped.”
“There is uncertainty right now. We don’t know how it’s going to go.
“We hope that crucial research is not stopped because every research that we do at HMS and elsewhere is a result of a highly competitive process. This is not funding that we get because of the largess of the federal government. We have to compete with every single lab around the entire country and it’s a function of that competitive process that we get grants to do the work that we do.”
Campus & Community
Garber message: ‘Upholding Our Values, Defending Our University’
Photo by Grace DuVal
April 21, 2025
1 min read
President announces suit against Trump administration over funding freeze
President Alan Garber on Monday sent a letter to the community announcing Harvard had filed a lawsuit in federal court to halt the Trump administration’s multibillion-dollar freeze on the Universit
President announces suit against Trump administration over funding freeze
President Alan Garber on Monday sent a letter to the community announcing Harvard had filed a lawsuit in federal court to halt the Trump administration’s multibillion-dollar freeze on the University’s research funding. Read his message, titled “Upholding Our Values, Defending Our University,” here.
Photo by Clayton Cubitt
Arts & Culture
What really scares Katie Kitamura
Ahead of Harvard visit, author talks performance, privacy, and horror inspiration for latest novel
Max Larkin
Harvard Staff Writer
April 21, 2025
7 min read
On Tuesday, the Mahindra Humanities Center will host the novelist Katie Kitamura, in conversation with Claire Messud, the Joseph Y. Bae and Janice Lee Senior
Ahead of Harvard visit, author talks performance, privacy, and horror inspiration for latest novel
Max Larkin
Harvard Staff Writer
7 min read
On Tuesday, the Mahindra Humanities Center will host the novelist Katie Kitamura, in conversation with Claire Messud, the Joseph Y. Bae and Janice Lee Senior Lecturer on Fiction in Harvard’s English department.
Kitamura published her fifth novel, “Audition,” earlier this month. Like several of her past books, including 2021’s acclaimed “Intimacies,” it’s taut, engrossing, and occasionally eerie — this time revealing the uncanny underside to life in middle age, inside and out of a family’s New York City apartment.
Kitamura was recently named a 2025 Guggenheim Fellow in fiction. She lives in Brooklyn with her husband, the novelist Hari Kunzru. The following interview was edited for length and clarity.
This latest book takes place under a cloud of uncertainty. In midlife, the central character may be very successful, or headed for a fall. She may be a mother, or not. She may be keeping secrets; her husband may be, too. It’s unsettling — is there any chance you’re becoming a horror novelist?
I love this question. With my last three novels, I’ve always thought of a genre as I was writing them. I wrote a novel called “A Separation,” and I thought of it as a missing-persons novel, a kind of mystery. And then I wrote a book called “Intimacies,” which is set in a war-crimes tribunal; I thought of that as a courtroom drama.
With this one, when I started writing it, I thought I’d like to be in conversation with horror, as a genre. The book that I had front of mind was “Rosemary’s Baby,” by Ira Levin — another book about troubled motherhood and New York real estate. These characters, this family: They’re trapped inside this apartment, and things grow increasingly frenetic.
There are also these uncanny moments — is this really my son? Is my husband all that he appears?
I think the really frightening moments in horror are when you look at something that you believe you understand, and you see something that is strange. In Shirley Jackson’s “The Haunting of Hill House,” one of the characters looks out the window and sees a part of the house she shouldn’t be able to see. Something about the entire geography and architecture of this home has changed.
I wanted to try to create that kind of feeling here: The central character is looking at people she believes she knows, and they seem like strangers to her. That, to me, is a very horror-adjacent feeling.
“The central character is looking at people she believes she knows, and they seem like strangers to her. That, to me, is a very horror-adjacent feeling.”
It’s been remarked that this novel has a pandemic feel to it. Was that conscious on your part?
Well, there’s not a single mask, or vaccine, or virus in the book. But it was written during the pandemic, and it was only really in the last couple of weeks that I realized in some ways it is very much a pandemic novel: a small apartment with family members coming home, not having enough space and really driving each other up the wall, on some level.
That was not my intention at all. But my feeling is that as a writer, you can’t help but breathe the air you breathe; all of it, everything in the sociopolitical atmosphere, it ends up on the page in some way.
The title is “Audition.” Your central character is an actor — very attuned to other people’s performances, altogether off-stage. And performance has been a theme of yours for a while — the essential malleability, or adaptability, of who we are, how we are with each other.
Yes. And I think people might read my work and think I’m writing a critique of that — that I’m pointing to those performances to say that they’re artificial in some way.
But it’s almost really the opposite: I think we learn how to be through performance, in a fundamental way. When I look at my children, I know they’re learning what it means to exist in the world in part by mimicking things they’ve seen around them. That’s very natural: to play different parts in different situations.
I just think as a novelist, I’m interested in those moments when the crack between parts starts to show, or the script wears thin. And for a brief moment you see something that is not as contained or controlled — and that can be frightening.
We might live with a spouse, a child, a parent for years and years — and never see some whole parts of them. It feels like you ask here how well we can really know each other.
To me, a successful relationship is one that allows the other person a certain degree of privacy.
I think this idea of full disclosure between two people is a kind of myth, and I’m not sure it’s a particularly healthy one. There are parts of myself that I want to have only to myself, that I don’t feel a profound need to share with my partner. And similarly, I believe there are parts of himself he should be able to keep for himself.
Your novels tend to reveal a real love of language and performance, of literature and visual art. And not only are you writing, but you teach writing at New York University. In the AI moment, in a time of ecological crisis, why does it seem so important to you?
The day after the election, my students came into my workshop and they said, “What is the point of writing fiction in times like this?” And I thought, there’s never been a moment when it feels more crucial to me to write fiction.
The way I put it to them is if books were not powerful, then why would they be being banned all across the country? If they don’t pose some kind of threat to power, why would they be continually under attack? To use language with precision and care, to have control of language, that’s going to be tremendously important over the coming years.
One purpose of fiction is, of course, to observe reality as it exists and as we see it. But part of it is also to imagine a different kind of reality. And if we can’t imagine a different kind of reality, there’s no way that we can bring it into being.
So you’d stick up for the English major.
I would! I was an English major, and I felt like I was able to go lots of different places with that. But also, when I think about my day, I think, the most optimistic thing I do every single day is to read a book.
When you read a book, you open up your mind to another person, and that’s actually quite profound. We are easier to subjugate when we’re divided, when we’re atomized. And books are actually a tremendous force of connection. If you are one of the people who is tending the fire, keeping that connection alive, that is really not nothing at all.
Campus & Community
Endowment offers Harvard flexibility but also risks
Harvard University. Stephanie Mitchell/Harvard Staff Photographer
Max Larkin
Harvard Staff Writer
April 19, 2025
6 min read
Economist speaks of balancing act between immediate needs and long-term planning
After years of careful stewardship, the University began this fiscal year with its endowment worth a record-se
Endowment offers Harvard flexibility but also risks
Harvard University.
Stephanie Mitchell/Harvard Staff Photographer
Max Larkin
Harvard Staff Writer
6 min read
Economist speaks of balancing act between immediate needs and long-term planning
After years of careful stewardship, the University began this fiscal year with its endowment worth a record-setting $53 billion.
But that overall number can conceal several important details. Most of the endowment is not only restricted by donors and held in separate funds, but the majority of those funds belong to one of the University’s 12 Schools. Less than 5 percent of the overall value is unrestricted and directly under the discretion of University leadership.
After the conflict that erupted last week between the University and the White House, the Trump administration moved to freeze billions in long-term research grants, with many more “under review.” The president has also argued that Harvard should lose its status as a tax-exempt institution.
To some degree, endowments can be used to allay financial uncertainty and cover unexpected costs. But those decisions come with costs of their own.
In this edited conversation, John Y. Campbell, who has served as the Morton L. and Carole S. Olshan Professor of Economics at Harvard since 1994, talked about how the endowment actually works.
Campbell’s research focuses on long-term investing, asset pricing, and personal finance. He served on the board of the Harvard Management Company, which oversees the endowment, from 2004 to 2011. And in 2021, he was a member of a working group that helped reimagine endowment management for Harvard’s Faculty of Arts and Sciences, or FAS.
In 2024, you co-wrote a paper on endowment management, using Harvard’s Faculty of Arts and Sciences as a kind of case study. What generally did you find?
That paper sought to give a framework for helping the FAS think about its long-run budget situation. I, along with my co-authors Jeremy Stein and Alex Wu, were motivated by a frustration with the usual accounting approach, which is all about managing this year’s cash flows so things add up.
So, for example, if you’re short of money and you can spend a little more from the endowment, that fixes the problem this year. But of course, it takes away resources that you would otherwise have in the future. It doesn’t help you in the long run.
This is an economist’s perspective on what can seem like a very large amount of money. You found that — in the case of FAS — the endowment is already being used to cover what would otherwise be a large budget deficit.
That’s right: When people in the Harvard community or the public at large look at the endowment, they look at those billions of dollars, and they think that that’s money that can just be spent on anything that the University wishes at any time.
There are two separate problems with that. Yes, much of the endowment is restricted — there are severe limitations on what the money can be spent on. But there’s another problem we identify: That in a certain sense, the endowment revenues have already been spent — to fund the ongoing existing operations of the University.
Those operations funded out of the endowment vary widely: professorships, research, construction among them. And then about a fifth of the annual distribution allows Harvard to offer really generous financial aid, just increased once more this spring.
Absolutely — and I’m all for that policy. But it does reduce the revenue that the School could otherwise collect, and thus it puts more burden on the endowment to cover expenses each year.
Then there are the exogenous shocks: financial crisis, recession, the COVID-19 pandemic. In those cases, a university can — and Harvard has — stepped up distributions to cover shortfalls elsewhere.
That’s right. You can do it in different ways. You can do a “decap” — using endowment funds for current expenses; you can adjust the payout rate; you can borrow against the endowment.
In a short-term emergency, like the pandemic or what may develop in today’s political environment, it may be entirely appropriate to do so. But the thing you need to be aware of is that, when you do that, you are easing your budget problems this year in return for a tighter budget in future.
Harvard’s approach to endowment management, like many others’, relies on targets and projections: It assumes 8 percent returns on investments, 3 percent inflation, and a payout of roughly 5 percent each year. But if the last 20 years have taught us anything, it’s that reality can be a great deal more volatile than that.
That’s right. Our way of looking at volatility — long adopted by Harvard financial administrators — is, in any one year, to find ways to smooth out its effects.
If the endowment does super-well one year — goes up by 25 percent — now you have a lot of new resources. But you don’t need to spend them all at once; in fact, it would be very imprudent to do so. Instead, you smooth it out, gradually increasing your spending in a cautious, well-planned way.
Meanwhile, there are also downside risks, too: In the wake of the financial crisis, in 2009, the endowment lost 27 percent of its value. And as of this week billions of federal dollars may be at risk of being frozen or revoked. What are the options now?
University leaders now need to sit down with the sort of spreadsheet framework that’s in our paper, and they need to do a scenario analysis: “How bad could this get?”
If there’s an endowment tax, if we lose “x” million dollars in sponsored research funding. You could even look at what might happen if Harvard lost its tax-exempt status.
What they are going to see is — if this a prolonged or permanent change — it’s going to have very meaningful implications for Harvard’s long-term future. And you’ll have to do some radical things: There will have to be a major change in spending or a major change in revenue — where you find it somewhere else.
You don’t have to do everything at once. That would be foolish. The luxury that Harvard’s endowment gives us is time — you have time to make change in an orderly fashion. But our framework says that if circumstances change so that you have less money coming in on a permanent basis, you are eventually going to have to fully adjust.
Health
Why bother?
Omar Rawlings/Getty Images
Jacob Sweet
Harvard Staff Writer
April 18, 2025
5 min read
What makes someone run 26.2 miles? Boston Marathon’s lead psychologist has heard it all.
Some runners cross the Boston Marathon’s finish line with hands held high, a look of elation on their faces. Others find themselves slumped in a medical tent with Jeff Brown, lead psychologist for
What makes someone run 26.2 miles? Boston Marathon’s lead psychologist has heard it all.
Some runners cross the Boston Marathon’s finish line with hands held high, a look of elation on their faces. Others find themselves slumped in a medical tent with Jeff Brown, lead psychologist for the Boston Marathon medical team.
“We’re not talking about, ‘Oh, I need ice for an ankle,’” Brown said about these finishers. “Someone is significantly overheated or underheated. They’re having terrible cramps. They’re disoriented. They might not know exactly where they are.” Laid out on cots are people with extremely low levels of salt in the blood, and others who are sad, fearful, and agitated for reasons they can’t explain. Brown’s role, along with his team of mental health clinicians, is to help perform psychological evaluations and recognize symptoms of a wide range of medical conditions.
Seeing these high levels of acute distress mere meters from the finish line, some might ask, “Why bother?” There are other ways to stay in shape or raise money that don’t require an extreme feat of cardiovascular and muscular endurance over multiple hours in unpredictable weather conditions.
It’s a question that Brown, a Harvard Medical School lecturer, McLean Hospital psychologist, and author of “The Runner’s Brain,” ponders each year as thousands of runners funnel past him. It will no doubt be on his mind Monday during the 129th edition of the Boston Marathon.
The reasons, Brown said, are inexhaustible, but what they have in common is that they’re “very, very personal, and really it is that personal energy and commitment that keeps people going, regardless of where they are in their lives.”
“In our world that’s rather cluttered with a lot of criticism, it’s a really nice way of getting affirmations in a healthy way,” psychologist Jeff Brown says about running the Boston Marathon.
Over the years, he’s met hundreds of people who are running for a recently deceased loved one, contending with a cancer diagnosis, and fundraising for a beloved charity. He’s met women who — monitored by medical staff — finished the marathon while far along in their pregnancies and other athletes who explicitly ignored their doctors’ instructions and ran with cracked femurs, torn muscles, recent sprains, and diabetic complications. “Perhaps it’s not a surprise,” said Brown, “that they meet us in the medical tent at some point.”
A marathon channels people’s energy into a methodical, focused pursuit, and, especially at Boston, one that provides some bragging rights. “It allows people to come to terms with themselves,” Brown said. “When it comes to self-concept and belief about one’s capabilities, we always do better when we have some sort of objective measure.”
That objective nature is crucial, Brown says. Not only do you complete a race, but when you finish, you get a medal placed around your neck. “I think of that as kind of this transformational moment,” he said, “because it’s something that was a hope that is now realized as a wish fulfilled. It’s the mind-body thing happening.”
He loves seeing people he’s treated gather enough mental and physical strength to leave the medical tent and finally collect their medals. “It’s almost like they had a chance to review their whole experience one more time,” he said, “and it might mean a little more to them.” He’s seen huge smiles, tears, and quiet reflection. “I think that’s just a reflection of the vast continuum of emotion and purpose and goals that people bring to running the Boston Marathon.”
“For a while there after you complete a marathon, you’re kind of a hero.”
Marathon runners invest enormously varying amounts of time and energy preparing for the race. Some are young, single people who sacrificed late nights out and lazy weekend mornings to set a personal record. Others are older, first-time runners who might be taking time away from their kids and spouses to complete a bucket-list item. A few are looking to advance professional running careers, and others show up having done barely any training at all.
A medal — and some bragging rights — are far from the only reward that motivates some people to invest thousands of hours into race-specific training and for others to ignore the sound medical advice of their doctors.
“In our world that’s rather cluttered with a lot of criticism, it’s a really nice way of getting affirmations in a healthy way,” Brown said. “And people, in our heart of hearts, we just want to be treated civilly.”
Running is also an opportunity to change your own conception of yourself and, at least for a few hours, how others view you. “For a while there after you complete a marathon, you’re kind of a hero,” Brown said. “You’ve done something that a lot of other people would never set out to do or think about doing, which is pretty darn cool.”
The mental side of running still fascinates Brown and has kept him on the Boston Marathon’s medical staff for more than 20 years.
“That one day, with 30,000 runners, there are 30,000 different ways of completing that marathon,” Brown said. “Imagine all the thinking and psychological experiences and reflections and motivations and negative thoughts and positive thoughts that went all those 30,000 different ways.”
Photos by Stephanie Mitchell/Harvard Staff Photographer
Nation & World
‘If you’re boring, you’re not going to educate.’
Liz Mineo
Harvard Staff Writer
April 18, 2025
long read
Randall Kennedy has blazed a path as an open-minded, nuanced, and independent thinker
Part of the
Experience
series
Scholars at Harvard tell their stories in the Ex
Kennedy, the Michael R. Klein Professor of Law, has also been unafraid to engage with the right. In 2020, the conservative Manhattan Institute invited Kennedy, a longtime questioner of critical race theory, to participate in a discussion on the topic. He eventually took other CRT critics on the panel to task for being too categorically dismissive.
“The great thing about his work is that you can never predict where he will end up — on racial justice, he sometimes seems conservative, sometimes liberal,” said then-Law School Dean Martha Minow in a 2013 profile of Kennedy. “In his field of race and the law, he is unique in the legal academy. I don’t know anyone else who has his commitment to pursuing the truth about controversial issues to wherever it goes.”
Kennedy, 70, was born in Columbia, South Carolina, and raised in Washington, D.C. His family’s move north from the Jim Crow South, along with his father’s pessimism about prospects for lasting racial justice in the U.S., left a deep imprint on Kennedy’s intellectual life.
The son of a postal worker and a schoolteacher, Kennedy attended the prestigious St. Albans School, did his undergraduate studies at Princeton, and was a Rhodes Scholar. He attended Yale Law School and has taught at Harvard since 1984. The author of seven books, Kennedy recently spoke with the Gazette about his life, career, and views on racial equality in the U.S. The interview has been edited for clarity and length.
Why did your father decide to move the family from Columbia to D.C.?
My parents were refugees from the Jim Crow South. My father was from Louisiana. My mother was from South Carolina. My father was a postal clerk and my mother a schoolteacher. They met at Fort Jackson, South Carolina, during World War II.
In the mid-’50s, soon after my birth, they left. An incident precipitated their move. It involved my father. He carried a gun as part of his employment driving a truck with the postal service. In some little town in South Carolina a white policeman stopped him. The policeman said, “We don’t allow negroes to have guns. Surrender yours.”
My father refused, and they had a standoff. My father got out of there fast, made it to Washington, D.C., got on the telephone, and said to my mother, “We’re moving.” Years later, I asked my father why he had left inasmuch as he and my mother had just built a house outside of Columbia. He said to me the following: “I thought that if we did not move, I was going to kill a white man, or a white man was going to kill me.”
Kennedy in his Harvard Law School office alongside a portrait of his father, Henry.
Did you experience discrimination while you were growing up?
Yes. The most memorable episodes transpired during trips from D.C. to South Carolina for holidays. Even as a kid, I sensed how the atmosphere changed as soon as we went over the 14th Street Bridge from D.C. into Virginia.
I remember a couple of times when my father was stopped by the police as we were driving in Jim Crow territory. The scenario was the same. A policeman would pull our car over. My father would ask, “Is there a problem, officer?” and the officer would say, “No, there’s no problem. I pulled you over because I noticed you have Washington, D.C., license plates, and I wanted you to know that we do things differently down here.”
The policeman was testing my father, and my father played along. He did what the police officer wanted, and what the cop wanted was for my father to call him “sir,” and be deferential, show that my father knew to stay in his place.
My father performed as required, and we went on our way. God bless my father for that! He put as his highest priority the well-being of his family. If he had to swallow his pride to accomplish that aim, so be it. What commitment. What poise. What discipline. What love. Yes, God bless my father for that.
How did your parents’ views on race influence you?
They influenced me greatly in all sorts of ways, some of which undoubtedly are beyond my conscious awareness. One was my father’s bone-deep pessimism about the possibility for lasting racial justice in America. He believed that the United States of America was created to be a white man’s country and would always be a white man’s country, and he never forgave the United States for its mistreatment of African Americans.
At his burial, because he was a veteran, a representative of the U.S. military was on hand to deliver an American flag, nicely folded, to my mother. I remember looking at my brother and smiling amidst the tears. We both knew that our father would have found this scene uproariously funny because my dad was not a patriot. He was an anti-patriot. The effort to understand the sense of aggrievement that he felt has been a big part of my intellectual life.
Soon after Kennedy’s birth in the mid-1950s, his parents, Henry and Rachel (pictured right), moved the family from South Carolina to Washington, D.C.
What memories do you have of your childhood?
I had a wonderful childhood! I spent several summers in Columbia, South Carolina, where I would stay with my Aunt Lillian. I had a great time even though during some of those summers no public parks were open. Why? Because South Carolina preferred to close the public parks rather than see them desegregated. But I had lots of friends, and we had lots of fun.
I also recall my childhood in D.C. with fondness. My parents bought a house two blocks from the Takoma public park. It was at that park that I learned to play football, baseball, and, most importantly, tennis. The tennis courts at Takoma public park are named after my father, Henry Kennedy Sr. He was known as “Mr. Tennis.”
To support his tennis-playing children, he learned everything that he could about the game and became quite proficient as a teacher and organizer of tennis tournaments. When he passed away, people in the neighborhood successfully petitioned the city government to name the tennis courts in his honor.
Is it true that you were a very good tennis player in your teens and that you played against Robert McNamara, who was then secretary of defense under President Lyndon Johnson?
I was a very good junior tournament player, as was my brother. He and I took care of the tennis courts at the St. Albans Tennis Club in Washington, D.C., on the grounds of the National Cathedral.
On Sunday mornings we were supposed to close the courts down during the Cathedral service. Usually, we did. But occasionally Defense Department Secretary Robert McNamara and National Security Adviser Walt Rostow would show up and beseech us to allow them to play. We even played doubles with them from time to time.
On one occasion, a chauffeur came to the courts and announced that the president was on the phone and wanted to speak with McNamara right away. The secretary left for a few minutes, returned, and play continued.
McNamara and Rostow were both quite competitive, but Rostow was the better of the two.
I read that tennis allowed you to attend the prestigious St. Albans School.
When my brother began taking care of the tennis courts at St. Albans, I would help him. When courts were open, and few people were around, I would practice with him.
The head pro at the club, who was also the tennis coach at the St. Albans School, saw me play and contacted my parents about applying to the school. They told him right off that we didn’t have St. Albans-level money. He told them that he could get me a scholarship if I could gain admission.
I ended up applying, gaining admission, and playing No. 1 on the school varsity from the eighth grade to the 12th.
I’ve gone to very fine schools, but the most transformative was St. Albans, where I fell under the sway of my favorite teacher, John F. McCune, known to generation of boys as Gentleman Jack McCune. He was my American history teacher and introduced me to the work of Richard Hofstadter at Columbia University and C. Vann Woodward at Yale University.
Reading their books changed my life. It was Mr. McCune who got me interested in the politics of historiography. He was a thoroughly inspirational figure. We shared a birthday and became close friends. I was with him the day before he died and was honored to speak at his memorial service at the National Cathedral.
“I have been surrounded for nearly 40 years by wonderful colleagues and students. Working here has been a blessing.”
How did you become interested in law?
Lawyering as an idea was an active presence in my household. My father spoke often about the time that he saw Thurgood Marshall argue the South Carolina whites-only primary case, Rice v. Elmore, in 1947.
The plaintiff was a Black business owner by the name of George A. Elmore, who challenged the exclusion of Black voters from the South Carolina Democratic primary. The judge ruled that the Democratic Party of South Carolina could no longer exclude qualified negroes from participating in primary elections.
And my parents were very proud of their friendship with the leading Civil Rights attorney in South Carolina, Matthew J. Perry. Most influential, however, was the example set by my brother, a 1973 graduate of HLS, who became a prosecutor, a Washington, D.C., judge, and then a judge on the United States District Court in the District of Columbia. (When he retired, he was replaced by Ketanji Brown Jackson, who now sits on the Supreme Court.)
You seem to have great admiration for your brother Henry.
Yes. He was a conscientious jurist and is a remarkably encouraging and loving big brother. He has been a wonderful cheerleader for me and our younger sister, Angela, who is also an attorney. He has been especially important to me since my wife passed away.
Kennedy with his oldest son, Henry, and late wife, Yvedt L. Matory.
Could you tell me how you met your wife?
My romance with Yvedt L. Matory began when I was a first-year student at Yale Law School, and she was a second-year student at Yale Medical School. We had met previously when she attended Sidwell Friends School, which was a 15-minute walk from St. Albans.
We married in June 1985 and had three children. She was a surgical oncologist at the Brigham and Women’s Hospital. She died of melanoma when she was only 48 years old. She passed away two months shy of what would have been our 20th wedding anniversary. I have lived a charmed life. The great tragedy that befell it was the death of my wife of blessed memory.
You served as a clerk to Justice Thurgood Marshall in 1983-1984. Can you talk about that experience?
It was thrilling to be able to work with and for “Mr. Civil Rights.” (Two of my co-clerks, by the way, are esteemed colleagues here: Terry Fisher and Howell Jackson.)
A strong argument can be made that Marshall was the greatest lawyer in American history. Think about the variety of posts he held — counsel for the NAACP, court of appeals judge, solicitor general, and Supreme Court justice — and the difficulties he had to overcome to make such positive contributions to American life and law!
I learned a lot working in the Marshall chambers. Seeing him up close was an inspiration that has deepened over time as I’ve gained a better sense of what he was up against and the patience, tenacity, poise, and grit that he displayed over a long period of time.
Did your father get a chance to meet Marshall?
My father met Justice Marshall on the next to last day of my clerkship. My father told “Mr. Civil Rights” how inspiring it had been to see him in that courthouse fighting for Black folks’ rights in a fashion that elicited grudging respect even from racist enemies.
Kennedy keeps this portrait of himself with Supreme Court Justice Thurgood Marshall in his office.
How did you come to Harvard Law School?
When I left Yale Law School, I was all set to go work for the NAACP Legal Defense Fund after my clerkships with Judge J. Skelly Wright and Justice Marshall.
But near the end of my third year of law school, I got a telephone call from HLS Dean James Vorenberg, who invited me to the Law School to talk with him and other members of the faculty about a career in legal academia. I shall always be grateful for his solicitude.
When I talk about my fondness for HLS, some friends tease me, calling me a Pollyanna. Too bad! It’s hard for me to imagine a better setting for a professor than Harvard Law School. I have been surrounded for nearly 40 years by wonderful colleagues and students. Working here has been a blessing.
What role does teaching play in your career compared to research and writing?
I thoroughly enjoy research and teaching and am engaged in writing all the time. The course that I’ve taught the most is contracts. For a long time, I felt considerable anxiety before every class. Over the past decade, though, that anxiety has steadily dissipated. Now teaching contracts is wholly fun. One of my upcoming books will be about contracts in the context of intimate associations — friendship, dating, marriage, surrogacy, adoption, etc.
Much of my teaching and almost all of my writing thus far has been about the regulation of race relations. I am about to complete a book on which I have been working for nearly a decade. It responds to the following question: How did protests over racial injustice in the mid-20th century change American law? I seek to answer that question in 800-plus pages.
“I am deeply alarmed by the effective mobilization of racial resentment that has gripped American politics.”
You wrote a book that examines the historical, cultural, and social significance of one of the most offensive words in the English language. Can you talk about it?
It is my only best-seller and has generated considerable controversy. It provoked an attempted assault at a bookstore reading and has triggered walkouts. It has also prompted lawyers to seek my assistance as an expert witness in employment discrimination suits, union grievance actions, and prosecutions for murders and assaults in which I have testified for the defense in some cases and for the state in others. By the way, the full title of my book is “Nigger: The Strange Career of a Troublesome Word.”
There were many people who said, “Well, you could have titled your book something else,” and there were people who would say, “You’re just trying to be sensationalistic.” My main goal was to educate, but how do you educate? If you’re boring, you’re not going to educate. You have to do something to get people’s attention and keep people’s attention. Do I try to do that? Sure, I try to do that. But I don’t view it as a bad thing.
Some in the media have, at times, labeled you a conservative. How do you respond to that?
Anybody who labels me conservative has not paid attention to what I have written over the course of my life. I believe that the United States is afflicted by unjustifiable hierarchies and inequalities that generate avoidable social misery. I think that it is scandalous that in a country this wealthy, there are so many people who are insecure regarding nutrition, shelter, healthcare, employment, and personal security due to crime and poor policing. I am in favor of reforms that aggressively address these problems.
The intellectual and ideological communities I find most attractive find voice in magazines such as The American Prospect, Dissent, The Nation, and The London Review of Books. If that makes me conservative, so be it.
I think that some observers have erroneously pegged me as conservative because I savor the company of intelligent conservatives such as my recently departed friend and colleague Charles Fried, because I participate enthusiastically in programming sponsored by conservative organizations such as the Federalist Society, because I strongly criticize certain policies such as mandatory Diversity, Equity, and Inclusion statements for university hiring and promotion, and because I indulge in certain rhetorical gestures that raise eyebrows — such as my use of the word “negro,” a term that I began using in 1984 at the insistence of my boss Thurgood Marshall and continue to use in homage to him and A. Philip Randolph, Martin Luther King Jr., Medgar Evers, W.E.B. Du Bois, my grandmother Lillian Spann, “Big Momma,” and countless other admirable souls.
Kennedy credits his grandmother Lillian Spann as a major influence.
You said that your father was pessimistic about the possibility of achieving lasting racial justice in America. What is your view?
Yes, my father was a pessimist on the race question. He did not believe that we shall overcome. The tradition he voiced is a strong tradition that includes the likes of Thomas Jefferson, Alexis de Tocqueville, Abraham Lincoln, Marcus Garvey, Malcolm X, and Derrick Bell. Tragically, there is much to which proponents of this tradition can point to substantiate their view that racial justice in America is doomed.
I place myself, however, in a different tradition, the tradition expounded by Frederick Douglass and Martin Luther King Jr., the tradition that embraces the possibility, indeed the likelihood, that racial decency will become an increasingly large and influential feature of American life.
I am deeply alarmed by the effective mobilization of racial resentment that has gripped American politics. But I take solace ironically in recognizing that a substantial part of that menacing reaction stems from remarkable successes in racial reform.
When I was born on Sept. 10, 1954, my home state of South Carolina explicitly subjected African Americans to a degraded, stigmatized status. It was not alone. Pigmentocracy was pervasive.
Yet, within a lifetime, by dint of remarkable struggles undertaken by Americans of all complexions, things changed sufficiently to enable a Black man to be president of the United States — a Harvard Law School alumnus who comported himself with consummate intelligence, grace, and honor.
Finally, what advice do you have for young lawyers?
Keep the fun quotient high by finding work that you love.
Indian economist and philosopher, Amartya Sen, the 1998 Nobel laureate in economics, talks about his life as the son of distinguished Hindu academics and how the inequities all around him in colonial India of the 1930s would shape his intellectual destiny.
Health
Stopping the bleeding
Terence Blue has spent his life managing hemophilia. A new gene therapy offers relief from constant worry and daily needles — ‘I am actually healing faster than I ever have.’
Alvin Powell
Harvard Staff Writer
April 18, 2025
long read
In early February, Terence Blue became the first patient in New England to receive a new gene therapy for hemophilia B, at Harvard-affil
Terence Blue has spent his life managing hemophilia. A new gene therapy offers relief from constant worry and daily needles — ‘I am actually healing faster than I ever have.’
Alvin Powell
Harvard Staff Writer
long read
In early February, Terence Blue became the first patient in New England to receive a new gene therapy for hemophilia B, at Harvard-affiliated Brigham and Women’s Hospital.
The first time Terence Blue understood he was different was during a kindergarten kickball game.
The other team fielded his kick and threw the big rubber ball at him to get him out. Blue tripped over the ball and hit his head on the ground, which didn’t rattle him much. What did was the reaction of the adults watching, who gasped and rushed over. Luckily, the 5-year-old had recently received clotting factor as part of his regular treatment for hemophilia. The factor did its job, stopping any bleeding from the tumble’s cuts and scrapes.
“I’d seen other kids take falls and remember thinking, ‘What’s all the fuss?’ Then I realized I really do need to be extremely careful about those things,” Blue said. “I realized then that I had to pay attention.”
For the next 27 years, Blue paid attention. Diagnosed at just months old, for years he visited the hospital two to three times a week for shots of the clotting factor missing from his blood. Eventually his mother learned to give him the shots and, when he was 8, a nurse taught him to do the task himself.
Over time, medical technology made living with hemophilia easier. Synthetic factors eliminated the risk of HIV, hepatitis C, and other pathogens that might lurk in donated blood. New factors last longer, allowing Blue to stretch the interval between shots to two weeks. Still, the idea he might go two months without a shot was more dream than reality.
“I remember being told ‘Within your lifetime, there may be a cure,’” Blue said. “It always seemed like a magic bullet or wishful thinking, a genie-in-a-bottle situation. But it’s starting to prove true. This is one step closer. So science, let’s keep making it happen.”
“I remember being told ‘Within your lifetime, there may be a cure.’ It always seemed like a magic bullet or wishful thinking.”
Terence Blue
In early February, Blue was the first patient in New England to receive a relatively new gene therapy for hemophilia B, at Harvard-affiliated Brigham and Women’s Hospital. Called Hemgenix, it was developed by drug maker CSL Behring and granted FDA approval in November 2022. It is part of surge of gene and cell therapies finally emerging from the long discovery pipeline that leads from the lab to patients’ hospital rooms.
Market reality vs. scientist and patient dreams
While that surge promises an expanding menu of gene and cell therapies — which are targeting more common conditions, have improved safety profiles, and improved vectors to carry them into the body — it also means the new treatments must face another force: the market. An implacable attention to balance sheets can negate both scientists’ long labors and patients’ fervent dreams.
“We’re seeing many more gene therapies coming into the clinic but the field is adjusting to the fact that not only does it matter that you can bring the gene therapies to the clinic and get them approved by the FDA, but there are market pressures and patient acceptance that has to be put into the equation,” said Roger Hajjar, head of Mass General Brigham’s Gene and Cell Therapy Institute. “So if the pricing is too high and too few patients actually benefit from the therapies, certain approved drugs in gene therapy are actually being withdrawn because there’s not enough payers to pay for them and not enough patients to benefit.”
Part of gene therapies’ difficulty is that they offer fewer opportunities to recoup research and development costs. Unlike medications for chronic diseases like diabetes, high cholesterol, and high blood pressure, which are taken regularly over a lifetime, gene therapies are typically given in a single dose that aims to correct disease-causing mutations and provide long-lasting benefits. That means eye-watering prices. Blue’s treatment, for example, lists for $3.5 million, though insurance companies typically negotiate lower rates, said his physician, Nathan Connell, associate director of the Boston Bleeding Disorders Center and vice chair of the Department of Medicine at Brigham and Women’s Hospital.
Blue’s doctor Nathan Connell.
Veasey Conway/Harvard Staff Photographer
That can mean little room for a market to grow and mature as patients and physicians learn about a treatment, according to Nathan Yozwiak, head of research for Mass General Brigham’s Gene and Cell Therapy Institute. The learning curve is often gradual, he said, and patients sometimes aren’t as enthusiastic as expected. Drugmaker Pfizer is already pulling its own hemophilia B gene therapy, Beqvez, from the market less than a year after its FDA approval, citing limited interest among patients and their doctors. In 2021, Bluebird Bio withdrew its beta thalassemia therapy Zynteglo from the market after a dispute with German regulators over its $1.8 million price. Even a groundbreaking treatment like Glybera, a treatment for a rare dysfunction in fat digestion and the world’s first gene therapy, was withdrawn in 2017 after treating just a single patient in five years.
But enthusiasm for gene therapy’s potential to transform patients’ lives, perhaps permanently, ensures that work continues. Today, the field is gathering additional steam as new treatments emerge from the pipeline connecting basic research to the hospital clinic, according to Hajjar, a pioneer in cardiac gene therapy for heart failure. An FDA tally of gene and cell therapies — in which healthy cells or those altered in the lab are given to the patient — shows 44 therapies have been approved in the U.S. Two were approved in 2022, five in 2023, and 18 in 2024 for conditions including multiple myeloma, invasive bladder cancer, sickle cell disease — which employed CRISPR gene editing technology for the first time — and cartilage defects in the knee, among others.
“Within the research side of things, there’s enormous, enormous optimism that’s reflected in the fact that the catalog of diseases for which researchers are pursuing a gene or cell therapy is growing every year,” Yozwiak said. “At the end of the day, I think we’re going to have a number of therapies that are actually very effective. Aligning that with the economic realities can be frustrating for researchers sometimes.”
‘I’m tired of needles’
Blue began talking about gene therapy with Connell two years ago after Hemgenix was approved by the Food and Drug Administration. Blue said it took several months to examine study data on his own, get used to the idea of introducing foreign genes into his body, and decide to move ahead. The idea that he might be able to unhitch his life from the needles that have been a daily reality, that he might be able to travel without needing an emergency supply of factor IX — just in case — and that he might escape the very real social pressures that have cost him friends grew on him.
“I’m tired of needles. They’ve been a part of my life forever,” Blue said. “It’s a small thing but it gets to you.”
After he decided to move forward, it took months more for the hospital to develop its own scientific review, internal approvals, and protocols before, finally, ordering the drug and administering the treatment.
The therapy takes advantage of viruses’ natural ability to home in on a particular organ and insert viral DNA into cells’ genetic code. In this case, bioengineers picked a virus that targets the liver — where the body makes clotting factor — and replaced the virus’ DNA with a corrected copy of the mutated gene that causes hemophilia B. Once in the liver, the virus inserts its payload into liver cells, jump-starting production of clotting factor IX, which is deficient or missing in hemophilia B, the rarer of hemophilia’s two forms and affecting about 15 percent of patients.
“You basically have a bit of a Trojan horse,” Connell said. “You want to get it into the liver and you use this mechanism to get it there. Patients come into the infusion center and it’s all done as an outpatient.”
The Promise of American Higher Education
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Because the genes causing hemophilia reside on the X chromosome, the condition is more common among men than women. Women have two copies of the X chromosome and even one normal gene usually allows their blood to clot normally. Men, with XY chromosomes, have only one chance: If their single X chromosome contains the mutation, they develop hemophilia. The U.S. Centers for Disease Control and Prevention says exact figures for those living with hemophilia are unknown, but a recent survey showed about 33,000 American males living with the condition.
Hemophilia care has come a long way, greatly aided by recent decades’ standardization of prophylactic injection of clotting factor for severe cases like Blue’s. Life expectancy was under 30 before the advent of modern hemophilia care but today approaches that of the average male population, according to a recent study by Canadian researchers.
“I called him and I think he was in a meeting at work. He didn’t know what to expect. I was really excited to tell him that it’s working.”
Nathan Connell
Though better, care remains imperfect, Connell said. Spontaneous bleeds are part of life, can be difficult to predict or control, and are often internal, affecting different parts of the body, including the brain. It’s not unusual for patients to experience spontaneous bleeds and wake up with a stiff elbow, knee, or other joint, a sign that blood has pooled within. The situation can be managed with an extra dose of clotting factor, but over time the bleeds damage the joints’ smooth, slippery cartilage, causing pain as well as making them prone to additional bleeding. Blue, today 33, has an ankle with an arthritis-like condition called hemophilic arthropathy because of trauma that began with an injury when he was young.
“Before we used prophylaxis, many people with severe hemophilia wound up in wheelchairs or using crutches because they would have frequent bleeds and then lose their ability to walk,” Connell said.
After decades managing the condition, Blue said the physical aspects of living with hemophilia have become routine, though never far from his consciousness. The social aspects are still difficult, however, and can be disheartening. He regularly must explain to companions why he can’t do certain activities and says that revealing his condition has cost him friends. Today, unless he’s engaged in an activity for which he believes companions need to know, he keeps silent.
Even with its limitations, Blue’s been able to live an active life. He got his black belt in tae kwon do when he was 14 — wearing extra pads when sparring — and outside of his work as an IT security engineer, enjoys bachata, a type of Latin social dancing, several times a week.
For something so cutting-edge and potentially impactful, receiving the therapy was fairly routine, if not dull. Blue’s infusion occurred on Feb. 6 and took about two hours. Watched closely by Connell and other members of his care team, Blue reported few side effects. After another four hours of observation, he was able to go home after reporting nothing amiss. In the weeks that followed, he began steroid treatment after enzymes in his liver became elevated. On. Feb. 20, he received his last injection of clotting factor IX, and as of mid-March, was tapering off steroids as liver function improved. By then, his factor IX levels, which had been less than 1 percent, had risen to 32 percent, in the mild hemophilia to low normal range.
“We hope it works. We have data that it works, but until you see it start to do something, you always have a little fear that maybe it’s not going to work out right,” Connell said. “I called him and I think he was in a meeting at work and he stepped out when he saw the number. He didn’t know what to expect. I said, ‘It’s working.’ And I was really excited to tell him that it’s working.”
Though physicians are hesitant to describe these therapies as “cures,” there is the prospect of yearslong or decadeslong effects. Ninety-four percent — 51 of 54 — of those treated with Hemgenix during the clinical trial still do not require factor IX prophylaxis three years later, according to the drugmaker’s website. Blue, who got a painful cut under his thumbnail in March, is still getting used to the healing journey he’s embarked on.
“I’ve had this happen many times before, so after I freaked out for a moment, I went to treat it,” Blue said. “My wife was sitting there looking at me, watching, and within seconds I realized that it was starting to resolve. This is abnormal for me. I’m ‘severe’ and am used to seeing bleeding happen for longer. In that moment I thought, ‘Wow, this is real. This is working. I haven’t had factor in ages, but here I am actually healing faster than I ever have in my life.’”
Vijay Kuchroo.Veasey Conway/Harvard Staff Photographer
Health
Immune-system strategy used to treat cancer may help with Alzheimer’s
Turning off checkpoint molecules freed microglia to attack plaques in brain, improved memory in mice
Alvin Powell
Harvard Staff Writer
April 18, 2025
7 min read
A new study raises the odds that a strategy already successful against some cancers may be deploye
Immune-system strategy used to treat cancer may help with Alzheimer’s
Turning off checkpoint molecules freed microglia to attack plaques in brain, improved memory in mice
Alvin Powell
Harvard Staff Writer
7 min read
A new study raises the odds that a strategy already successful against some cancers may be deployed against Alzheimer’s. The research, which highlights the role of an immune system “checkpoint” molecule, showed improved cognition in tests with mice. It was published earlier this month in Nature.
In this edited conversation, the Gazette spoke with Vijay Kuchroo, the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School and Brigham and Women’s Hospital, and director of the Gene Lay Institute of Immunology and Inflammation of Brigham and Women’s Hospital, Massachusetts General Hospital, and Harvard Medical School.
Kuchroo, who was a senior author on the paper, outlined work that deleted the expression of a molecule called TIM-3, which blocks brain immune cells called microglia from attacking Alzheimer’s plaques, freeing the cells to clear plaques and restoring memory.
Your work was done in a model of late-onset Alzheimer’s disease. What proportion of cases is it?
Most cases of Alzheimer’s disease (AD), 90 percent to 95 percent, are late-onset. The molecule that we studied, called TIM-3, was linked by a genome-wide association study to late-onset Alzheimer’s and was found to be a genetic risk factor for the disease. There’s a polymorphism in the TIM-3 gene, HAVCR2, in patients with AD. TIM-3 is an inhibitory molecule utilized by the immune system to turn off the immune cells once activated. TIM-3 belongs to a group of inhibitory molecules called checkpoint molecules, which have been exploited for treatment of cancer.
Checkpoint molecules stop the body from attacking itself?
That’s one way to put it. If your immune system gets activated, the checkpoint molecules restrain the immune system from getting out of hand.
The best example is that every time you get an infection like the common cold, your lymph nodes get swollen because you make millions and millions of T cells to fight the virus. Once the infection goes away, checkpoint molecules come in to reduce the number of T cells to a normal level.
Cancers have exploited these checkpoint molecules for their own survival, and every time a T cell goes to attack a tumor cell, the tumor cell induces expression of checkpoint molecules so the T cells don’t attack the tumor cells. The T cells become dysfunctional or exhausted, and the tumor survives.
The new twist is that in Alzheimer’s disease, there is the accumulation of plaque in the brain that doesn’t get cleared by macrophage-like cells called microglia. The microglia show an increased expression of the checkpoint molecule TIM-3.
They’re basically the immune cells of the brain?
Microglia are the immune cells of the brain and have other important functions. During development, synapses are being formed, and synapses are how memory is stored. The problem is that even transient experiences make memories, so you want to get rid of some memories that are not being used again. So, the major job of microglia cells during development is to prune synapses that have not been used often enough in order to sharpen and sustain your memory.
After you’re born and have developed memories, you don’t want to lose them, so at about 28 to 40 days after birth in the mouse and a few months to few years in a human, there is a developmental mechanism by which microglia stop pruning to keep the memories that are made.
To stop the microglia from pruning, they increase expression of the checkpoint molecule TIM-3, and these microglia cells become homeostatic, they do not phagocytose anymore.
That’s good because you don’t want to prune your own memory, but it’s bad as you get older and accumulate gunk in the brain, which can’t be cleared. Who’s going to clean it up? Microglia cells have become homeostatic, and TIM-3 keeps them from engulfing the accumulated gunk, which results in the formation of plaques.
What’s the difference in TIM-3 in an older person who has Alzheimer’s disease, versus not?
There’s a polymorphism in the gene, and in Alzheimer’s patients with the polymorphism, TIM-3 is highly expressed on microglia, significantly more than those that don’t have the disease.
So that all that TIM-3 keeps the microglial cells at homeostasis and not attacking amyloid beta plaques even though they’re harming the brain?
Yes, microglia cells should be clearing amyloid plaque, but they don’t. We discovered this molecule on T cells in the immune system, but it is 100 times — in some cases 1,000 times — more expressed on microglia when they get activated.
So, the same molecule that’s shrinking the T cell population to normal size after infection is being used by microglia cells to stop them from excess pruning. But it’s also a liability, because it inhibits them from attacking plaques that accumulate in Alzheimer’s disease.
You tested this with lab mice who have the HAVCR2 gene — which makes TIM-3 — deleted?
Yes, these mice were made to test the role of TIM-3 in immune system autoimmunity and cancer.
We used the same mice. We genetically deleted the gene, and in these mice the microglia don’t express TIM-3 when the microglia get activated. That enhances clearance of the plaques and changes plaque behavior.
Toxic plaque has fingerlike projections that enter into the brain, but with the microglia nibbling on them, the plaques become compact. So, the deletion of TIM-3 in microglia not only reduces the number of plaques, it also changes the quality of the plaque. These mice actually get the cognition back. Not completely, but the cognitive behavior of these mice improves.
And when we talk about measuring cognitive behavior for mice, we’re talking about their ability to remember and navigate mazes?
That’s correct. When they have plaque burden in their brains, they don’t remember as much. They also have less fear. If you put them in an open space, normal mice will go to a corner, so they don’t wind up as prey. But if they have plaques, they sit there in the center of the maze and don’t hide. When you get rid of the plaques, memory comes back, and that response comes back, because an appropriate level of fear is important for survival.
What would a TIM-3 therapy for Alzheimer’s disease in humans look like?
Therapy would use an anti-TIM-3 antibody or a small molecule that can block the inhibitory function of TIM-3.
What’s the potential of this to make a difference against Alzheimer’s disease? After several failures of major drug trials, recently there have been some successes, though those showed just minor improvement.
Because amyloid beta is also in the endothelium in the blood vessels, a lot of antibody doesn’t go to the brain, it attacks the blood vessels, leading to strokes due to vascular damage, limiting the use of anti-amyloid antibodies in AD. Since TIM-3 has selective expression, existing anti-TIM-3 antibodies can be repurposed for treatment of AD.
How long did this work take?
Five years; each experiment takes about eight, nine months. I want to emphasize that this was in collaboration with a colleague here, Oleg Butovsky at the Ann Romney Center for Neurological Disease. There were about six people, three from my lab and three from his lab, who worked tirelessly to do these experiments.
What happens next?
We are trying to see whether human anti-TIM-3 can halt development of plaques in the brains of Alzheimer’s disease mouse models. We have a mouse model in which the human TIM-3 gene has been inserted, which will be very suitable for testing various candidate antibodies for human disease.
This research was funded in part by the National Institutes of Health.
Campus & Community
Slave trade database moving to Harvard
Henry Louis Gates Jr. (left) talks with David Eltis.Photos by Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
April 17, 2025
4 min read
Publicly accessible digital tool compiles four decades of scholarship on more than 30,000 voyages and 200,000 people
SlaveVoyages, a groundbreaking tool for data
Henry Louis Gates Jr. (left) talks with David Eltis.
Photos by Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
4 min read
Publicly accessible digital tool compiles four decades of scholarship on more than 30,000 voyages and 200,000 people
SlaveVoyages, a groundbreaking tool for data on history’s largest slave trades, is getting a new home.
Word of the project’s upcoming move was shared recently by Henry Louis Gates Jr., the Alphonse Fletcher University Professor and director of the Hutchins Center for African & African American Research. “I’m pleased to tell you today that the SlaveVoyages site, with all of its databases, will live in perpetuity here at Harvard University,” Gates announced at a conference dedicated to celebrating the open-access resource.
SlaveVoyages was the result of nearly four decades of scholarly contributions, with researchers from multiple institutions working painstakingly to digitize handwritten records from archives worldwide.
Today, its multisource dataset, currently housed at Rice University, features information on more than 30,000 slaving vessels that traversed the Atlantic between the 16th and 19th centuries. Also documented are details on nearly 221,000 individuals involved with the trans-Atlantic slave trade, including ship captains and the humans they trafficked.
The project’s website, launched in 2008 at Emory University, brings data to life with rich visualizations. A time-lapse animationtracks each of the individual voyages on a map of the trans-Atlantic slave trade. A pair of 18th-century French slaving ships, both bound for present-day Haiti, have been recreated in 3D video based on surviving drawings.
As SlaveVoyages expanded, the Hutchins Center provided key funding along with the National Endowment for the Humanities, the Andrew W. Mellon Foundation, and Emory University. Stepping up to help support the project in its new home is the Harvard & the Legacy of Slavery Initiative (H&LS).
“Education is central to the mission of the initiative.”
Sara Bleich
“Education is central to the mission of the initiative,” said Sara Bleich, vice provost for special projects and the leader of H&LS. “SlaveVoyages’ databases build on the curiosity of Harvard students who catalyzed the University’s ongoing reckoning with its ties to slavery. By cofunding the project with the Hutchins Center, the initiative can help amplify knowledge-sharing and visibility, empower scholars and students worldwide, while also reaffirming our commitment to truth.”
The April 3-5 conference, hosted by the Hutchins Center, attracted researchers associated with the project as well as those it has inspired.
“This conference brings together generations of scholars who dedicated their lives to unearthing centuries of data to help us understand in detail and with nuance the contours of the slave trade — a quantifiably brutal trade in human beings that spanned oceans and continents while devastating millions of lives,” said Gates, who is also a member of the initiative’s Advisory Council.
Over three days, sessions covered a wide range of topics suggesting the global scope of the slave trade. The conference kicked off with a panel on the genetic impacts of the slave trade featuring David Reich of Harvard Medical School, Kasia Bryc of the Broad Institute, as well as scholars from Johns Hopkins University and the National Center of Medical Genetics of Cuba.
Rice University associate professor of history Daniel B. Domingues da Silva, who currently serves as host of the SlaveVoyages project, unpacked his findings on Brazil’s 19th-century slave trade. Jorge Felipe-Gonzalez, an assistant professor of history at University of Texas at San Antonio, discussed the potential integration of AI into the database. Jane Hooper, a professor of history at George Mason University, explored shipboard uprisings on Indian Ocean voyages.
A final panel addressed the South West Pacific trade, with Francis Bobongie-Harris, Queensland University of Technology educator and researcher emphasizing the human cost.
David Eltis is awarded the W.E.B. Du Bois Medal.
Gates opened one of the afternoon sessions with a surprise for SlaveVoyages originator David Eltis, an emeritus professor of history at Emory University and the University of British Columbia, bestowing on him the W.E.B. Du Bois Medal “in recognition of his unyielding vision that brought to life a resource that has transformed our understanding of one of the most cataclysmic and consequential economic, social, and cultural forces unleashed in the history of humanity.”
The medal is “especially fitting” for Eltis, Gates added, given the fact that Du Bois, the first Black American to earn a Ph.D. from Harvard University, wrote his 1895 dissertation on efforts to suppress the trade of enslaved Africans in the U.S.
Nation & World
What we still need to learn from pandemic
Princeton University professors Frances Lee (left) and Stephen Macedo share their findings.Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
April 16, 2025
6 min read
School closures, shutdowns caused lasting damage, and debate was shut down in favor of groupthink, public policy experts say
Social di
Princeton University professors Frances Lee (left) and Stephen Macedo share their findings.
Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
6 min read
School closures, shutdowns caused lasting damage, and debate was shut down in favor of groupthink, public policy experts say
Social distancing, school closures, and stay-at-home orders became hotly disputed during the 2020 COVID-19 crisis. How should these protocols be viewed today?
The new book “In Covid’s Wake: How Our Politics Failed Us” by a pair of Princeton University professors finds no evidence these “non-pharmaceutical interventions” actually reduced mortality rates. What the co-authors do find is that the measures did significant damage to U.S. society — with many mainstream scientists, journalists, and scholars reluctant to make a frank appraisal.
“We argue that, in the pandemic, disagreement was moralized prematurely, and dissent was treated intolerantly,” said co-author Stephen Macedo, the Laurance S. Rockefeller Professor of Politics at the University Center for Human Values. “We see these as failures of educated elites to live up to some of our own deepest values of being open to criticism and divergent points of view.”
In a talk last week hosted by the Department of Government, Macedo and co-author Frances Lee, a professor of politics and public affairs, outlined the book’s thesis and took tough audience questions.
Macedo kicked things off with a survey of pandemic planning documents that predate COVID-19. Reading John M. Barry’s “The Great Influenza” (2004) had piqued the interest of former President George W. Bush. His administration advanced a strategy of containment, influenced by mathematical modelers who said children would likely be primary carriers.
A National Strategy for Pandemic Influenza Implementation Plan, released by the Centers for Disease Control in 2006, emphasized the promise of school closures. “They predicted that school closures, by themselves, could secure a 50 percent reduction in peak death rates,” Macedo said.
Over the next 13 years, severalexperts cautioned against what the American Civil Liberties Union characterized as “aggressive, coercive actions” in its own 2008 pandemic preparedness report. Frequently emphasized was the danger of disproportionately harming vulnerable populations, including kids from low-income families.
“But the policy flipped on a dime in March 2020,” Macedo said, citing a February 2020 World Health Organization-China report from Wuhan. “The joint mission report unequivocally urged every country in the world to embrace what was, in effect, a zero-COVID policy by the severe implementation of lockdown policies.”
There was some pushback from infectious disease experts in the early days of the pandemic. But, the authors say, the marketplace of ideas was experiencing its own lockdown by the October 2020 release of the Great Barrington Declaration, with its urgent call to relax restrictions for those at minimal risk. The statement, written by three epidemiologists with distinguished credentials, drew thousands of signatories. But it was quickly branded by critics in public health and government as “dangerous” and “fringe.”
“Part of it was that people settled on a wartime framing,” Macedo offered, citing the titles of two early pandemic memoirs — Deborah Birx’s “Silent Invasion” and Sanjay Gupta’s “World War C.”
Co-author Lee picked up the thread by examining pandemic outcomes across 50 states. At first, blue and red states implemented similar measures, she recalled. But the policymaking appeared deeply polarized by Labor Day.
“Across the South, the Plains, and the Mountain West, schools reopened in the fall of 2020,” Lee said. “But nearly half of public schools around the country were still closed in March 2021.”
By January 2023, states led by Republicans had suffered mortality rates nearly 30 percent higher than their Democratic-led counterparts, according to the co-authors’ assessment of CDC data. But they found no evidence that blue states benefited from longer school closures and stay-at-home orders.
“If you examine COVID mortality across the period before vaccines became available,” Lee said, “there’s not a statistically significant difference.” This was true even when controlling for the percentage of elderly, uninsured, or obese residents. A separate analysis, published in the Lancet in 2023, surfaced similar conclusions.
Yet these non-pharmaceutical measures came at a steep cost, with Lee quickly rattling off more than a dozen examples — from a spike in alcohol-related deaths to emptied downtown business districts and learning losses for schoolchildren.
The injury was also fiscal. Congress authorized more than $5 trillion in COVID relief spending, aimed mostly at helping Americans stay financially afloat during the shutdowns.
“In the first quarter of 2020, total debt held by the public leapt from 80 percent of gross GDP to more than 100 percent,” Lee explained. “This higher plateau persists post-pandemic — and that higher level of indebtedness also entails a higher cost for debt service that puts constraints on our ability to respond to the next economic crisis or address other priorities.”
Are educated elites, largely aligned with the Democratic Party, finally ready for an honest reckoning with the COVID era’s groupthink? Macedo has his doubts. He pointed to an August 2023 JAMA Network Open article outlining varieties of misinformation shared by physicians on social media, with the aim of helping governments and professional societies censor bad actors.
Included were the Wuhan lab leak theory, concerns about the harms of masking children, and suggestions that natural infection can contribute to herd immunity. “All of these matters, as of August 2023, were either true or at least arguable,” Macedo said.
In a lightning-round review of the book’s lessons, Macedo emphasized the need for open debate and viewpoint diversity in navigating future crises.
“We also need greater honesty on the part of public officials — especially in public health,” he concluded, noting the resulting hit to the field’s credibility. “There’s too much of a tendency to not tell the whole truth, because they see their role partly as messaging and trying to nudge people’s behavior. But I think we are owed honesty about the limits of their knowledge.”
During the Q&A session, one attendee pushed back on the authors’ call for prioritizing honesty in a public health emergency. Given the pandemic’s devastating loss of life, the comparison to wartime governments protecting national security was made.
In response, Macedo referred to previous scholarship on the Vietnam War, including Barbara W. Tuchman’s “The March of Folly” (1984). “We think this is another case where people are engaging in wishful thinking — trying to get the public to go along and not being transparent about the cost of these measures and the likelihood of success,” he said.
Jian-Xiang Qiu (left) and Suyang Xu adjust the lasers Photo by Dylan Goodman
Science & Tech
Hunting a basic building block of the universe
Researchers find way to confirm existence of axions, a leading dark matter candidate
Yahya Chaudry
Harvard Correspondent
April 16, 2025
5 min read
No one has ever seen axions. But scientists have theorized their existence as a way to explain some o
Researchers find way to confirm existence of axions, a leading dark matter candidate
Yahya Chaudry
Harvard Correspondent
5 min read
No one has ever seen axions. But scientists have theorized their existence as a way to explain some of the biggest questions in particle physics, including the nature of dark matter, the mysterious substance that constitutes most the mass of the cosmos. Confirming the existence of axions could lead to insights into the history and composition of the universe itself.
Now, in a groundbreaking experiment, a team of scientists led by Harvard and King’s College London have made a significant step toward using quasiparticles to hunt for axions, which are hypothesized to actually make up dark matter. The findings, recently published in Nature, open new realms for harnessing quasiparticles to search for dark matter and develop new quantum technologies.
“Axion quasiparticles are simulations of axion particles, which can be further used as a detector of actual particles,” said senior co-author Suyang Xu, assistant professor of chemistry. “If a dark matter axion hits our material, it excites the quasiparticle, and, by detecting this reaction, we can confirm the presence of the dark matter axion.”
Frank Wilczek, the Nobel Prize-winning physicist who first proposed axions, credits these findings as a major breakthrough in the study of these particles.
“The jury is still out on the existence of axions as fundamental particles that beautify the basic equations of physics and provide the cosmological dark matter,” Wilczek said. “But now, thanks to these ingenious new experiments, we know for sure that the Nature makes use of the underlying ideas. Axions now join holes, phonons, plasmons, and a handful of other ‘quasiparticles’ we find emerging as ingredients of matter, available for new scientific and technological creations.”
The experimental work was led by Jian-Xiang Qiu, a Harvard Griffin Graduate School of Arts and Sciences student in the Xu lab. Researchers who assisted in the study include Yu-Fei Liu, Anyuan Gao, Christian Tzschaschel, Houchen Li, Damien Berube, Thao Dinh, Tianye Huang, as well as an international team of researchers from King’s College, UC Berkeley, Northeastern University, and several other institutions.
The researchers utilized manganese bismuth telluride, a material renowned for its unique electronic and magnetic properties. By crafting this material into a 2D crystal structure, they established a platform ideal for nurturing axion quasiparticles. This process involved precision nano-fabrication engineering, in which the material was meticulously layered to enhance its quantum characteristics.
“Our lab has been working on this kind of interesting material for almost five to six years, and it is both a very rich material platform and also it is very difficult to work with,” said first author Qiu. “Because it’s air-sensitive, we needed to exfoliate down to a few atomic layers to be able to tune its property properly.”
Operating in a highly controlled environment, the team coaxed the axion quasiparticles into revealing their dynamic nature in manganese bismuth telluride. To accomplish this delicate feat, the team utilized a series of sophisticated techniques including ultrafast laser optics. Innovative measurement tools allowed them to capture movements of axion quasiparticles with precision, turning an abstract theory into a clearly visible phenomenon.
By demonstrating the coherent behavior and intricate dynamics of axion quasiparticles, the researchers not only affirmed long-held theoretical ideas in the field of condensed-matter physics but also laid the groundwork for future technological developments. For example, the axion polariton is a new form of light-matter interaction that could lead to novel optical applications.
In the field of particle physics and cosmology, this new observation of the axion quasiparticle can be used as a dark-matter detector, which the researchers have described as a “cosmic car radio” that could become the most accurate dark-matter detector yet.
Dark matter remains one of the most profound mysteries in physics, constituting about 85 percent of the universe’s mass without detection. By tuning into specific radio frequencies emitted by axion particles, the team aims to capture dark-matter signals that have eluded previous technology. The researchers believe it could help discover dark matter in 15 years.
“This is a really exciting time to be a dark-matter researcher. There are as many papers being published now about axions as there were about the Higgs-Boson a year before it was found,” said senior co-author David Marsh, a lecturer at King’s College London. “Experiments proposed that axions emitted a frequency in 1983, and we now know we can tune in to it — we’re closing in on the axion and fast.”
Xu is confident that the team’s multifaceted approach enabled their pioneering success.
“Our work is made possible by a highly interdisciplinary approach involving condensed-matter physics, material chemistry, as well as high-energy physics,” Xu said. “It showcased the potential of quantum materials in the realm of particle physics and cosmology.”
Moving forward, the researchers plan to deepen their exploration of axion quasiparticles’ properties, while refining experimental conditions for greater precision.
“The goal for the future is obviously to have an experiment that probes axion dark matter, which would definitely be super beneficial for the whole-particle physics community that is interested in axions,” said senior co-author Jan Schütte Engel, a physicist at UC Berkeley.
This research was partially funded by the U.S. Department of Energy, the Air Force Office of Scientific Research, and the National Science Foundation.
Campus & Community
‘This is weakening the United States.’
Photos by Veasey Conway/Harvard Staff Photographer; photo illustration by Liz Zonarich/Harvard Staff
Anna Lamb
Harvard Staff Writer
April 15, 2025
4 min read
Scholars react to Trump administration actions against Harvard and other institutions
Harvard on Monday rejected demands by the Trump administration that link $9 billion
Photos by Veasey Conway/Harvard Staff Photographer; photo illustration by Liz Zonarich/Harvard Staff
Anna Lamb
Harvard Staff Writer
4 min read
Scholars react to Trump administration actions against Harvard and other institutions
Harvard on Monday rejected demands by the Trump administration that link $9 billion in federal funding to compliance with changes to University governance and hiring practices, viewpoint “audits” of academic departments, students, and faculty, and other measures.
The funding, more than $2 billion of which was frozen hours after Harvard responded to the demands, supports research that “has led to groundbreaking innovations across a wide range of medical, engineering, and scientific fields,” according to a message President Alan Garber sent to the Harvard community Monday afternoon.
The government has cited concerns about campus antisemitism in explaining its decision to halt funding at Harvard and several other institutions of higher education.
On Tuesday, we sought reactions to the funding cuts in conversations across campus.
Amberly Xie
Third-year Ph.D. student in applied physics
“I feel like at some core level, it violates our rights as people and researchers and scientists — and as a university as well,” said Xie, whose research focuses in part on quantum computing.
Like many students and scholars, she worries that major funding cuts at institutions such as Harvard will slow or in some cases halt scientific progress.
“Universities play a major role because it’s where a lot of research takes place,” she said. “There are companies and startups that do this kind of work, but I feel like it’s truly in universities where a lot of the fundamental work is done, and a lot of the pioneering work in terms of allowing us to not only better understand the platforms like the ones I work with, but also help put them into real-world applications.”
Andrew Tyrie
Senior fellow at the Mossavar-Rahmani Center for Business and Government at Harvard Kennedy School; former member of the House of Commons in the British Parliament; current member of the House of Lords
“I think there’s a much bigger job to be done, and that is for all those who disagree with the dramatic and, in my view, dangerous decisions being taken by the new administration to speak up,” said Tyrie, who is studying regulatory reforms in advanced Western economies in his time at the Kennedy School.
Everyone engaged in academia and politics should be outraged by the Trump administration’s stance, he said.
“And of course, as a non-U.S. citizen, I am concerned about the wider effects on the world — both the prospects for growth and prosperity, but also for its security and stability,” he said. “What I’m not asking is for people to speak up in the interests of the world, but to speak up in the interests of the United States of America. This is weakening the United States and imperiling the prosperity and the security of millions of Americans.”
Joshua Cherniss
Visiting fellow at the Edmond and Lily Safra Center for Ethics; associate professor of government at Georgetown University
“I study, to some extent, authoritarian regimes, and I think that some of what we’re seeing — while it’s not equivalent to fully formed authoritarianism — is starting to approach it in terms of trying to have the government dictate the ideas that are taught, that can be expressed and that can’t be expressed,” said Cherniss. “I think that it’s important that Harvard and other universities not buckle under what I think is pretty clearly an assault on academic freedom and university self-governance.”
Cherniss studies political theory, particularly defenses and critiques of liberalism. He said he worries about the impact of funding freezes on fellow scholars inside and outside his field.
“We may have to cut a lot of the most socially useful work that we do in medical sciences and technology — things that have really benefited America and benefit the world in very practical ways,” he said.
Campus & Community
The food was good. The conversation was better.
Professor Michael Sandel (right) led a conversation for the “Food For Thought” event.Photos by Grace DuVal
Nikki Rojas
Harvard Staff Writer
April 15, 2025
5 min read
‘Our Harvard’ brings students together to tackle tough issues
First they met for coffee. This month they came together for a full meal.
Spurred by the
Professor Michael Sandel (right) led a conversation for the “Food For Thought” event.
Photos by Grace DuVal
Nikki Rojas
Harvard Staff Writer
5 min read
‘Our Harvard’ brings students together to tackle tough issues
First they met for coffee. This month they came together for a full meal.
Spurred by the Gaza conflict, Nim Ravid ’25, an economics concentrator from Israel, wanted to find new ways to connect students across the College. Last summer, he co-founded “Our Harvard” with five of his peers, and one of their first efforts was pairing students for coffee chats meant to encourage conversations across differences.
On April 1 at Smith Campus Center, the group hosted a larger gathering: “Food For Thought: Our Harvard College,” an evening of conversation during which students offered their perspectives on a range of issues.
Following the event, students gathered in the lobby of the Smith Campus Center to share a meal.
Ravid was heartened by the results.
“It was the most vulnerable and honest I’ve ever heard Harvard students communicating with each other, which I think reflects our efforts to bring students from across campus together to this event and create an environment where students assume best intentions and say what they actually think,” he said.
The conversation, which was followed by a meal provided by Harvard University Dining Services, was moderated by Michael Sandel, Anne T. and Robert M. Bass Professor of Government.
“There’s a risk with conversations like this, that everyone will think it’s much safer to just celebrate diversity, eat some food, and go home, but that would miss the learning and the struggling and the wrestling with the questions out of which friendships and genuine dialogue can be forged,” Sandel told the crowd.
One by one, members of Our Harvard and those in the audience spoke about feeling ostracized for their identity, national origin, or beliefs, and finding it difficult to establish friendships across differences. Frederico Araujo ’25, an Our Harvard founder from Portugal, discussed his struggles connecting with students from Brazil.
“Sometimes when I came to Annenberg and I initiated a conversation that I hoped would be about our shared language, our shared food, our shared music, and our many shared traditions between Brazilian and Portuguese culture, I would actually get the cold shoulder,” he said. “I don’t need to give a history lesson about the historical background between Portugal and Brazil, but I wasn’t aware that those historical ties would be sufficient for someone to ignore my friendship.”
In response, Sandel said, “Sometimes seeming similarities can be startling for their distance.”
The conversation covered the Israel-Palestine conflict, with Ravid and others expressing their fears about sharing personal experiences. Several participants with no direct connections to the war said they have found themselves uncomfortably in the middle of friends with different views.
Angie Gabeau ’25, another founding member of Our Harvard and a sociology concentrator, acknowledged being apprehensive when the conversation turned to the Middle East, but said that it was beneficial in the end.
“I’m actually glad that it was brought up,” she said. “If you are talking about the hottest topic on the market right now and are still able to make yourself vulnerable to discussing with people who might not agree with you, then other cases will be a lot less daunting.”
Angie Gabeau ’25 is a founding member of Our Harvard.
Gabeau, a Boston native, told the audience that she arrived at Harvard hoping to connect with other Black students after coming from a predominantly white high school. The Winthrop House resident joined the Black Students Association, the Kuumba Singers, and Omo Naija x The Wahala Boys, an African dance troupe.
“I was so happy to be able to find a community here,” she said. While emphasizing the importance of these groups, Gabeau also said that she believes it’s important to build relationships across differences. “This conversation wasn’t to shadow the importance of affinity organizations but seeing how we can both share our cultures, ideas, values, and morals with each other, while being able to feel safe here at Harvard,” she said after the event.
Harvard College Dean of Students Tom Dunne found it meaningful “that the core group of students who are organizing this are seniors in their last weeks on campus.”
Ravid expressed his hope that Food for Thought will help spark similar movements at Harvard. “I also hope this event will encourage others to not treat other students differently based on their identity, but rather for who they are,” he said. “I hope students will really take time to get to know each other before they judge.”
Gabeau noted that Our Harvard has set goals that do not ask too much of students.
“I don’t want this to come off as, ‘We can all be friends and everything’s going to be perfect,’ because that’s not really what we’re trying to do,” she said. “There’ll be people who have disagreements that won’t foster friendship. I wouldn’t want people walking around campus pretending to be friends.”
She continued: “It’s not supposed to be creating a perfect utopian universe but rather pushing people to go the extra mile in terms of seizing all the opportunity in the different pockets of joy and growth that there is on campus.”
Gina Raimondo.Photo by Martha Stewart
Work & Economy
When making positive change, sometimes you ‘break things’
Key is to avoid hurting people in process, Gina Raimondo says
Clea Simon
Harvard Correspondent
April 15, 2025
5 min read
If you want to make things better, says Gina Raimondo, that means things are going to have to change — and sometimes that means you “break things.”
For
When making positive change, sometimes you ‘break things’
Key is to avoid hurting people in process, Gina Raimondo says
Clea Simon
Harvard Correspondent
5 min read
If you want to make things better, says Gina Raimondo, that means things are going to have to change — and sometimes that means you “break things.”
For example, the former U.S. Commerce secretary and Rhode Island governor said that when she was leading the Ocean State, she cut taxes every year, raised the state minimum wage, and made community college tuition free. She also cut 30 percent of the state’s regulations.
“I don’t think we should just accept things because they’re the way things have been done,” Raimondo ’93 said last week during an Institute of Politics forum on “The Future of U.S. Competitiveness.”
This willingness to make changes, she acknowledged, may sound similar to the tactics of Elon Musk’s DOGE. The difference? “Execution matters,” she said. “You can’t hurt people in the process.”
That focus on ensuring fairness and opportunity for regular Americans came early and has remained with her throughout her political career.
The granddaughter of immigrants who stressed hard work, Raimondo, who was instrumental in shaping the Biden administration’s Infrastructure Investment and Jobs Act, credited her large Italian family with getting her into politics. When Ronald Reagan was elected president, she recalled, “My dad kept saying ‘What about the little guy who gets up in the morning and goes to work? Who’s sticking up for us?’
“As I got older and I saw that American Dream being out of reach,” she said. “It motivated me to get involved in politics.”
The IOP discussion with Jeff Liebman, director of the Taubman Center for State and Local Government and Robert W. Scrivner Professor of Social Policy, turned to Raimondo’s tenure as Commerce secretary. The two first focused on the early days when supply chains slowed as COVID raged. “The first thing we had to do was understand the complexity of supply chains,” she said.
In response to endless calls about various essentials that were suddenly not available, “We built spreadsheets for critical supply chains, like pharmaceuticals — and then, under President Biden’s leadership, we got to work making friends with other countries,” she said.
Citing Biden’s belief, she said, “America can’t and shouldn’t go it alone. America is best when we make friends; he sent us to Southeast Asia to build relationships with Indonesia, with the Philippines,” and beyond.
In addition to forging or strengthening those relationships, the Biden administration responded with the CHIPs and Science Act, aimed at making scientific essentials domestically. Liebman asked her how that played out.
“Most semiconductors are a commodity, and many of them are made overseas — a lot in China,” Raimondo responded. “It wouldn’t be a national security disaster if there was a backlog of iPhones. But artificial intelligence — all AI — runs on leading-edge chips. So much of our intelligence-gathering capacity depends on leading-edge chips. That directly affects our national security, and we make zero” of the chips in question.
“By 2030, we’ll be making a quarter of those chips. That’s a success,” she said.
She also defended the legislation’s fiscal responsibility. “We insisted that for every dollar we put out there, $10 of private-sector dollars come in,” she said. “When we left, we had about 13 private-sector dollars for every dollar that we put in.”
Such self-reliance is essential, she said. Citing China’s BYD electric cars, which are heavily subsidized by the Chinese government and then sold inexpensively around the world, she said, “Free trade is great if everyone plays by the rules. China does not play by the rules. I think having more reciprocity is reasonable.”
Looking back on her time with the Biden administration, she acknowledged mistakes, including — perhaps — too many compromises.
“Politics is not perfect,” she acknowledged. “We did get a lot done, though. People who make those critiques may not know how hard it is to get things done in a 50-50 Senate and a tiny margin in the House.”
Raimondo also defended Biden’s stimulus act, which some blame for inflation. “I was the governor of Rhode Island during COVID,” she said. “In the couple of months after COVID broke out, in a state of about a million people, I had 110,000 file for unemployment insurance.”
Recalling the “pit in my stomach,” she worried, “How am I going to get these people back to work?
“It was really scary,” she said. “It’s easy to say the stimulus shouldn’t have been so big it led to inflation. But nobody says if it wasn’t big enough that unemployment would have continued.”
She also defending tacking so-called social programs onto economic ones. “Companies that wanted our money needed to find workers,” she said. “They’re not going to have enough workers without women, and they’re not going to get women without a childcare plan.
“They weren’t social programs. They were labor market programs designed to be a steward of taxpayer money.”
At the Perkins School for the Blind in Watertown, students try their hand at Boston Line Type, developed in 1835. Braille didn’t make its way to the U.S. until almost 20 years later.Photos by Niles Singer/Harvard Staff Photographer
Campus & Community
New experiences at their fingertips
Course on tactile reading shows students ‘Why Braille Matters’
Nikki Rojas
Harvard Staff Writer
April 15, 2025
6 min re
At the Perkins School for the Blind in Watertown, students try their hand at Boston Line Type, developed in 1835. Braille didn’t make its way to the U.S. until almost 20 years later.
Course on tactile reading shows students ‘Why Braille Matters’
Nikki Rojas
Harvard Staff Writer
6 min read
In his “Literature and Disability” course taught last spring, Professor Marc Shell noticed Katie Sevier ’25 taking notes on her HIMS QBraille XL display, a device that connects to her laptop and allows her to type in braille.
A discussion between Shell and Sevier on the importance of the history, theory, and practice of tactile writing systems used by the visually impaired led the pair to create a course not seen at peer institutions. Now the professor and the student are both the teachers. Their class is called “Why Braille Matters.”
“For me, braille is a sign of access, of freedom, of independence,” Sevier said. “Having this course come to life means so much. It is a course affirming a component of the blind experience — braille — which is so integral to many blind people’s experiences.”
On Thursday afternoons, Sevier can be found preparing for a class as fellow students and two trained guide dogs fill a small room at Dana Palmer House on Harvard’s campus. Throughout the semester, Sevier and Shell have prioritized highlighting different experiences by inviting guest speakers from the blind community or those who work with the blind community.
“This is and is not a course about disability,” Shell said. “It is really a course about reading and writing systems, and that is the main linkage with Comparative Literature.
Katie Sevier ’25 (left) and Marc Shell brought students to Perkins School for the Blind as part of their class, “Why Braille Matters.”
“The history of reading and writing goes back thousands of years to tactile forms. These forms might be called ‘pre-braille.’ As our research is now revealing, blind people had many methods of reading and writing,” he added.
Sevier and Shell take an integrative dual approach to teaching “Why Braille Matters.” She instructs students on braille code and blindness education, while he leads discussions on the literary, philosophical, and neurological aspects of the raised-dots writing system. For Sevier, the course is deeply personal. The 23-year-old lost her vision at 6 years old due to intracranial hypertension and began learning braille the summer after kindergarten.
During a recent class, students — who come from across the University — discussed the 1980 film “To Race the Wind,” the story of blind lawyer, activist, and author Harold Krents ’67, J.D. ’70. The film documents Krents’ experience navigating Harvard’s complex campus as an undergraduate. Sevier and other visually impaired students also shared their own stories about learning to move through the Yard.
Amy Ojeaburu ’25 examines a large tactile globe that was once used by Helen Keller.
A student looks at a braille bingo card.
The first brailler was produced at Perkins in 1951. The braille typewriter has changed little over the years.
“What was really validating and empowering to see was the way Katie had written out the directions that she used to teach another blind student how to navigate a specific route to the Yard,” said Emma Vrabel ’25, a former white-cane user who now has a guide dog. From this, she said, sighted students were better able to understand “how exhausting” it can be to have to memorize various routes across campus.
“Harvard is a hard place to navigate,” said Vrabel, who is still able to see faces, gestures, and large print. “At the beginning of every semester, I teach my guide dog, Holly, how to find our different class buildings and landmarks. Holly has been super helpful in making that a faster, more efficient process, but it’s still a lot of labor.”
Following class discussion, students break into small groups to attempt to decode different film and literature titles in braille.
“The course started out with tactile sensitivity training, where you’re building up your ability to tactilely distinguish between small differences,” said Sevier, who went on to explain that braille characters include six dots placed in two columns of three dots. Letters of the alphabet, known as “Grade One Braille,” are determined by the number and arrangement of dots. “Grade Two Braille,” or contractions, are characters that stand for parts of words or even whole words.
Alex Waysand ’27, an international student from France with an interest in languages, noted the challenge of learning to read braille.
“This is a commonly shared experience among students in the class, but I was struck to discover how insensitive the tips of my fingers were and how hard it was to decipher braille characters,” he said.
Beyond animated, philosophical classroom examination on the writing system and Sevier’s lessons on reading braille, students visited Perkins School for the Blind in Watertown. There they were given a tour of the library and museum and had the opportunity to use a giant tactile globe that was favored by Helen Keller, Radcliffe College Class of 1904. The globe, which was built in 1837 and stands 13 feet in circumference, was the first thing that Keller touched when she arrived at Perkins as a student at the age of 8.
Vrabel, who is writing her thesis on Perkins’ outreach program and lived there last summer, was glad her Harvard classmates had the chance to acquaint themselves with the extraordinary world at Perkins. “It was really cool to come back with the class and experience all the exhibits and see people who probably would not have been in the space otherwise,” she said.
Now, more than halfway through the semester, Sevier said she’s happy with how the course has manifested. “I am very impressed with everyone’s ability to put themselves out of their comfort zones to learn more about the braille code,” she said, adding that she hopes students will take with them “the pride and joy blind people have within their community … and that students will be able to see this in other spaces.”
Shell and Sevier plan to teach another iteration of this course next academic year.
Campus & Community
Harvard won’t comply with demands from Trump administration
Harvard University.Photo by Grace DuVal
Alvin Powell
Harvard Staff Writer
April 14, 2025
5 min read
Changes pushed by government ‘unmoored from the law,’ Garber says. ‘The University will not surrender its independence or relinquish its constitutional rights.’
Harvard on Monday rejected demands from the Tr
Harvard won’t comply with demands from Trump administration
Harvard University.
Photo by Grace DuVal
Alvin Powell
Harvard Staff Writer
5 min read
Changes pushed by government ‘unmoored from the law,’ Garber says. ‘The University will not surrender its independence or relinquish its constitutional rights.’
Harvard on Monday rejected demands from the Trump administration that threaten $9 billion in research funding, arguing that the changes pushed by the government exceed its lawful authority and infringe on both the University’s independence and its constitutional rights.
“The University will not surrender its independence or relinquish its constitutional rights,” Harvard President Alan Garber wrote in a message to the community. He added: “No government — regardless of which party is in power — should dictate what private universities can teach, whom they can admit and hire, and which areas of study and inquiry they can pursue.”
Garber’s message was a response to a letter sent late Friday by the Trump administration outlining demands that Harvard would have to satisfy to maintain its funding relationship with the federal government. These demands include “audits” of academic programs and departments, along with the viewpoints of students, faculty, and staff, and changes to the University’s governance structure and hiring practices.
The $9 billion under review by the government includes $256 million in research support for Harvard plus $8.7 billion in future commitments to the University and several renowned hospitals, among them Mass General, the Dana-Farber Cancer Institute, and Boston Children’s. Late Monday, the Trump administration announced that it was moving to freeze $2.2 billion in grants and $60 million in contracts to Harvard.
The Trump administration has been critical of Harvard’s handling of student protests related to the Gaza war. It has accused the University of failing to adequately protect Jewish students on campus from antisemitic discrimination and harassment, in violation of Title VI of the Civil Rights Act of 1964.
Garber emphasized that Harvard remains committed to fighting antisemitism, including through a series of campus measures implemented over the past 15 months. In addition, he said, the University has complied with the Supreme Court decision that ended race-conscious admissions and has worked to broaden intellectual and viewpoint diversity at Harvard.
The University’s objectives in fighting antisemitism will “not be achieved by assertions of power, unmoored from the law, to control teaching and learning at Harvard and to dictate how we operate,” Garber said. “The work of addressing our shortcomings, fulfilling our commitments, and embodying our values is ours to define and undertake as a community.”
Harvard is just one of dozens of schools targeted by the Trump administration in recent weeks. Last month, the Department of Education sent letters to 60 universities, including Columbia, Northwestern, the University of Michigan, and Tufts, threatening enforcement actions for noncompliance with anti-discrimination provisions in the Civil Rights Act of 1964. The administration has taken the additional step of freezing research funding at several institutions.
Robust research and innovation partnerships among universities, the federal government, and private industry date to World War II. Government-backed research conducted at schools across the nation has led to countless discoveries, devices, treatments, and other advances that have helped shape the modern world. Computers, robotics, artificial intelligence, vaccines, and treatments for devastating diseases have all stemmed from government-financed research that crosses from labs and libraries into industry, creating new products, companies, and jobs.
In March, a report from the nonprofit United for Medical Research showed that every dollar of research funded by the National Institutes of Health — the nation’s largest funder of biomedical research — generates $2.56 in economic activity. In 2024 alone, the NIH awarded $36.9 billion in research grants, generating $94.5 billion in economic activity and supporting 408,000 jobs, according to the report.
In an interview on Monday, Daniel P. Gross, an associate professor of business administration at Duke University and co-author of a recent NBER working paper on the decades-long partnership between the U.S. government and higher ed, said the withdrawal of research funding from universities would be “catastrophic” to American innovation.
“Universities are such an integral part of the modern U.S. innovation system that it wouldn’t stand without them,” said Gross, who taught at Harvard Business School before moving to Duke.
George Q. Daley, dean of Harvard Medical School, said that biomedicine has long depended on a strong partnership with the federal government, one that has paid off for Americans in life-saving advances. Just this month, he noted, the Medical School’s Joel Habener was recognized with a Breakthrough Prize for his work on GLP-1, which has led to diabetes and anti-obesity drugs. Daley also cited transformative work in cardiovascular health, cancer immunotherapy, and a host of other conditions.
“As we look back over the 70 years of that partnership, it has returned brilliantly on the investments the government has made,” he said. “The fact that we have Harvard, MIT, and all these extraordinary hospitals, that has been a magnet for venture capital investment and now we have the pharmaceutical research infrastructure being brought into our community. All of this is a jewel in the crown of American bioscience.”
The threat to that science is an even bigger issue in an era of stepped-up competition with China, he added.
“It seems self-defeating and injurious to the economy and to U.S. leadership in biotechnology and pharmaceuticals,” Daley said. “It feels like the hammer has come down in a way that threatens something that is intrinsic to U.S. leadership and ultimately to our economic competitiveness with places like China, which are investing very, very heavily in biotechnology.”
In his message to the community, Garber stressed the contributions of university research to scientific and medical progress while underlining the importance of independent thought and scholarship.
“Freedom of thought and inquiry, along with the government’s longstanding commitment to respect and protect it, has enabled universities to contribute in vital ways to a free society and to healthier, more prosperous lives for people everywhere,” he said. “All of us share a stake in safeguarding that freedom.”
Arts & Culture
Becky G gets real at Cultural Rhythms
RAZA Ballet Folklórico performs at Sanders Theatre.Photos by Veasey Conway/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
April 14, 2025
4 min read
Artist of the Year applauds student performers for ‘leaning into authenticity’
Dance dominated the 39th annual Cultural Rhythms festival as students showcased impressive f
RAZA Ballet Folklórico performs at Sanders Theatre.
Photos by Veasey Conway/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
4 min read
Artist of the Year applauds student performers for ‘leaning into authenticity’
Dance dominated the 39th annual Cultural Rhythms festival as students showcased impressive footwork from around the world.
“It just feels right to be surrounded by so many young individuals who are dedicating themselves to representation and to leaning into authenticity,” said five-time Latin Grammy nominee Becky G, honored as Artist of the Year at the April 5 production.
Since 1986, Cultural Rhythms has united the Harvard community for a celebration of the cultural and ethnic diversity of its student body. The tradition has grown into a weeklong series, including a fashion show and food fair. The grand finale, hosted by the Harvard Foundation, is a student-led performing arts showcase and Artist of the Year ceremony at Sanders Theatre.
Becky G acknowledges the audience after receiving her award.
Harvard University
The award’s past recipients include musical performers Lady Gaga and Rubén Blades as well as actors Courtney B. Vance, Angela Bassett, Eva Longoria, and Viola Davis.
“It’s a heavy-hitting list of incredible individuals who’ve accomplished so many things,” Becky G, 28, told the Gazette. “I feel like I’m just getting started.”
This year’s around-the-world tour featured Harvard Dankira Dance Troupe, with its Ethiopian- and Eritrean-inspired folk dances, and Bhangra, which pumped up the crowd with electric Punjabi moves. Audience members were pulled to their feet by Omo Naija x The Wahala Boys, who put on a Vegas-worthy dance skit. Becky G was seen cheering from her seat as Bryant Valenzuela ’25 and Mariachi Veritas x RAZA Ballet Folklórico performed Mexico’s varied movement and musical traditions.
The 2½-hour program, titled “Global Encounters,” included musical performances by 10 student groups. A highlight came when the Kuumba Singers of Harvard College offered their powerful rendition of “Can’t Give Up Now” by the duo Mary Mary. The song includes an adapted chorus from the Black gospel classic “I Don’t Feel Noways Tired.”
The Harvard Asian American Dance Troupe.
Harvard University
Omo Naija x The Wahala Boys.
Harvard University
Sebastian Feune (center right) rehearses with other members of Mariachi Véritas.
Harvard University
Habiba Braimah, senior director of the Harvard Foundation for Intercultural and Race Relations, offered her thoughts on the impact of these sets. “We are reminded that art is powerful,” she told the audience. “Dance, storytelling and music is healing, and culture — all cultures, your culture — matters in a world that makes you feel divided, where our identities might be misunderstood or even challenged.”
Becky G was honored for artistic excellence and other positive contributions. At the end of the evening, the singer, songwriter, actress, and activist took the stage with festival co-directors Anapaula Barba ’25 and Hayat Hassan ’25 for a conversation covering everything from career to mental health and philanthropy.
Becky G, whose real name is Rebecca Marie Gomez, has been open in the past about her anxiety. At Sanders, she encouraged those in the midst of mental health struggles to ask for help, no matter what cultural taboos they face.
“I realized as I got older that my responsibility isn’t necessarily to be a role model but to be a real model,” Becky G said in an interview. “That means speaking to the fact that I am imperfect and that I make mistakes.”
With more than 28 billion career streams and high-profile roles in the films “Power Rangers” (2017) and DC’s “Blue Beetle” (2023), along with her hit songs “Shower” and “Mayores,” performed with Bad Bunny, Becky G uses her position to raise awareness for vulnerable communities.
“One thing that comes to mind is that there’s no lack of talent and there’s no lack of passionate individuals who are willing to do what it takes to do the work, but there is a lack of opportunity,” she said.
She is active with Altadena Girls, an organization supporting girls who lost their homes in this year’s Eaton Canyon fire.
A big fan of the late Selena Quintanilla — aka the Queen of Tejano Music — as well as contemporary reggaeton artists, she celebrated the fact that Latinx artists no longer need to “cross over.” Breaking into the U.S. market may have required performing in English for past generations. But Spanish-speaking singers today can stick to their roots.
“When we open the door for ourselves, we’re holding it open for the next generations and we’re making things better brick by brick,” said Becky G, the first Latina to receive Artist of the Year in a decade.
Campus & Community
Helping the U.S. fight addiction, cancer, other afflictions
April 14, 2025
4 min read
A snapshot of research backed by partnership between government agencies and higher ed
Examples of how Harvard scholars are tackling real-world problems — through critical research supported by federal funding — appear daily in the Gazette. The following is a snapshot of recent coverage.
Helping the U.S. fight addiction, cancer, other afflictions
4 min read
A snapshot of research backed by partnership between government agencies and higher ed
Examples of how Harvard scholars are tackling real-world problems — through critical research supported by federal funding — appear daily in the Gazette. The following is a snapshot of recent coverage.
The fentanyl crisis hits close to home for Harvard-trained researcher Travis Donahoe, whose research probes the forces driving opioid deaths and the best ways to intervene. “Ending this epidemic is one of the most important changes we can make to improve the health — and dignity — of all Americans.”
A stem cell therapy developed at Mass Eye and Ear safely restored the cornea’s surface for 14 patients in a clinical trial. When a person suffers a cornea injury, it can deplete the limbal epithelial cells, which can never regenerate. People with these injuries often experience persistent pain and visual difficulties.
Researchers from Harvard-affiliated Mass General Brigham developed olfactory tests — in which participants sniff odor labels that have been placed on a card — to assess people’s ability to discriminate, identify, and remember odors.
“We saw a critical gap in prenatal care and an opportunity to define the genetic disorders that are treatable during this time,” said the study’s senior author. “These conditions are actionable — meaning that, empowered with diagnostic information, we can intervene early and improve outcomes.”
Chemist and Ph.D. candidate Brandon Campbell sees in silver an opportunity to lower the cost of medicine in the U.S., where consumers pay nearly three times more than 33 other nations in the Organization for Economic Cooperation and Development.
A Harvard startup has developed a “third way” of pulling moisture from the air that works like a coffee filter. It uses much less energy than traditional air conditioners and dehumidifiers and is more stable than desiccant systems.
The fate of the universe hinges on the balance between matter and dark energy, which is the force thought to be driving the universe’s accelerating expansion. New research suggesting that dark energy, widely thought to be a “cosmological constant,” might be weakening suggests the standard model of how the universe works may need an update.
New insights on how inflammation sparked by the body’s immune response alters mood and behavior could lead to alternatives to traditional psychiatric drugs that act directly on the brain. These treatments would work indirectly by altering immune chemicals outside the brain.
“Studies have previously investigated dietary patterns in the context of specific diseases or how long people live,” said one of the researchers. “Ours takes a multifaceted view, asking, how does diet impact people’s ability to live independently and enjoy a good quality of life as they age?”
Over the course of his Harvard doctoral studies, Rob Devlin must have made 100 of a new kind of mini-lens, experimenting with materials and prototyping new designs to bend light like a traditional camera only using a series of tiny pillars on a millimeter-thin wafer.
For the first time, scientists succeeded in trapping molecules to perform quantum operations. The technology promises speeds exponentially faster than classical computers, which could enable game-changing advances in fields including medicine, science, and finance.
Campus & Community
Garber message: ‘The Promise of American Higher Education’
Photo by Grace DuVal
April 14, 2025
1 min read
President shares University’s response to Trump administration's demands
President Alan Garber on Monday sent a letter to the Harvard community with an update on the University’s response to recent demands by the Trump administration tied to federal support for research. Read
Garber message: ‘The Promise of American Higher Education’
Photo by Grace DuVal
1 min read
President shares University’s response to Trump administration's demands
President Alan Garber on Monday sent a letter to the Harvard community with an update on the University’s response to recent demands by the Trump administration tied to federal support for research. Read his message, titled “The Promise of American Higher Education,” here.
Nation & World
Leveraging social capital to defend worthy causes, people in need of representation
Legal scholar and Law School grad returns for student panel
Liz Mineo
Harvard Staff Writer
April 14, 2025
3 min read
Margaret Montoya, J.D. ’78.Veasey Conway/Harvard Staff Photographer
Law school provides job security with high earning potential, legal scholar Margaret Montoya, J.D. ’78,
Leveraging social capital to defend worthy causes, people in need of representation
Legal scholar and Law School grad returns for student panel
Liz Mineo
Harvard Staff Writer
3 min read
Margaret Montoya, J.D. ’78.
Veasey Conway/Harvard Staff Photographer
Law school provides job security with high earning potential, legal scholar Margaret Montoya, J.D. ’78, said during a March 27 student panel at Harvard Law School. But it also gives students cross-functional skills, social capital, and the chance to work for the greater good.
Montoya, the first Latina to be accepted to Harvard Law School, urged the students to give back by engaging with communities in need of legal representation, finding worthy causes to defend, and advocating for democracy.
“I was asked a question just a moment ago, ‘Why would you return to Harvard?’” said Montoya. “I return for you … I would hope that you go out and change the world. You can use the social capital offered by a Harvard degree … It is a certificate that’s worth a lot. Use it. Come back here. And help others.”
“You can use the social capital offered by a Harvard degree … It is a certificate that’s worth a lot. Use it. Come back here. And help others.”
Margaret Montoya, J.D. ’78,
A native New Mexican, Montoya, now professor emerita, has been at the University of New Mexico Law School since 1992. She has taught courses in constitutional rights, torts, contracts, clinical law, and employment law, and has written about race, ethnicity, gender, culture, and language.
After graduating from HLS, Montoya was awarded Harvard University’s Frederick Sheldon Traveling Fellowship, which allowed her to travel through Europe and Asia. Over the years, she has often returned to campus to meet and talk with students about how to make the most of their legal educations.
During her talk, Montoya compared her experience as a law student in the 1970s, when she was the only Latina student in the HLS classrooms, to that of students today.
“When I look at you, the demography, the social geography is very different,” said Montoya. “I arrived as a child from a low-income family … This is a place that teaches you about power. That is something that is worth experiencing because in order to change the society we have to understand power.”
Montoya asked student panelists what they felt were the biggest gaps in their legal education. Many responded that their courses sometimes lacked perspective on how the law affects the lives of average Americans, skipping over issues of race, social class, politics, and history.
“There’s a lot missing in the education of law students. First and foremost, it’s how the law impacts real people,” said Liz Ross, J.D. ’21 and a Ph.D. candidate in history. “That was probably the biggest gap that I saw when I was here … I think empathy is missing in legal education.”
When asked by Montoya how they enhanced their legal education, panelists underscored the importance of working with like-minded people by forming study or reading groups, getting involved with student organizations, and bringing new voices and perspectives to classrooms.
Montoya asked students to use their law degrees to help vulnerable communities, defend social and racial progress, and protect democracy when it’s threatened by authoritarian forces. A law degree offers tools to become guardians of democracy, she said.
“Harvard transfers social capital to those of us who are here and who graduate,” Montoya said during an interview after her talk. “We can turn that social capital to become stewards of democracy. We can name ourselves as being on the side of justice. Harvard Law School gives us the social capital to be able use different tools to change the status quo.”
Nation & World
EPA plans target climate change initiatives
The Salata Institute series, “Harvard Voices on Climate Change,” featured Harvard Law School’s Carrie Jenks and Richard Lazarus with Salata Director Jim Stock moderating.Veasey Conway/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
April 14, 2025
6 min read
Environmental law experts say rollbacks will reverse advances in r
The Salata Institute series, “Harvard Voices on Climate Change,” featured Harvard Law School’s Carrie Jenks and Richard Lazarus with Salata Director Jim Stock moderating.
Veasey Conway/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
6 min read
Environmental law experts say rollbacks will reverse advances in recent decades
A Harvard expert in environmental law said a recent set of Trump administration regulatory changes targeting initiatives in the climate change battle will reverse progress made over decades.
Richard Lazarus, Harvard Law School’s Charles Stebbins Fairchild Professor of Law, said the late U.S. Sen. John McCain described the first Trump administration’s approach to cutting government programs as using a “meat cleaver” rather than a scalpel.
“I would say that Trump 2.0 in the first 71 days has been more akin to a nuclear explosion, with a bull’s eye on programs related to climate change,” Lazarus said on April 1, during an online discussion of the administration’s new goals for the Environmental Protection Agency disclosed last month.
Regulatory whipsawing is common, Lazarus said, as administrations undo what they see as predecessors’ harmful actions and overreach. Efforts in Washington D.C. today, however, go far beyond disagreement over how to regulate, questioning whether to regulate at all.
Carrie Jenks, executive director of HLS’ Environmental and Energy Law Program, agreed, saying that in mid-March the EPA laid out a roadmap of 31 steps it would take, targeting issues including climate change-related regulation, power plant and greenhouse gas reporting requirements, and support for electric vehicles. The steps also included reconsidering restrictions on the oil and gas industry, mercury standards that affect coal power plants, wastewater regulations for oil and gas development, air quality standards, and others.
Lazarus and Jenks’ assessments were part of a conversation hosted by the Salata Institute for Climate and Sustainability. The hourlong event, part of its “Harvard Voices on Climate Change” series, was moderated by Salata Institute Director James Stock, Harvard’s vice provost for climate and sustainability and the Harold Hitchings Burbank Professor of Political Economy.
A key administration initiative, they said, is the launch of a formal reconsideration of the 2009 “endangerment finding.”
That finding, ordered by the Supreme Court in 2007, concluded that the buildup of greenhouse gases in the atmosphere endangers human health. It provided the legal foundation under the Clean Air Act for government regulation of climate warming gases like carbon dioxide and methane.
Jenks described the finding as “a trigger” for subsequent regulation, so an attractive target for those seeking to undermine federal action on climate change. Attacking the decision on the basis of scientific fact, however, may be difficult, since the science is well-established.
Instead, Jenks said the administration might try to argue that the EPA doesn’t have the legal authority to regulate greenhouse gases or has the discretion to choose not to.
“I think they’re going for more legally risky strategies that have more damaging outcomes if they’re successful,” Jenks said. “Each action taken by the EPA under [Barack] Obama, [Joe] Biden, and even in some cases, the first Trump administration, recognized climate change, and the debate was about how to regulate, not whether to regulate. Now, I think, it’s very different from what we’ve seen in the past.”
Whatever approach they take, Jenks said, they will have to go through a process of proposing regulatory change, taking public comments, and finalizing the rule, which takes time and allows environmental groups and others who disagree to voice their opinions.
“I’m sure those actions will then be litigated, and any regulatory action should need to be grounded in the statutory criteria that Congress has required EPA to consider, which generally has at least one component connected to emissions or pollution reduction,” Jenks said.
Jenks said she expects the EPA to move quickly, but that could become difficult if staff cuts deplete the agency’s expertise on these matters, as the underlying rationale for regulatory change has to have supporting data.
Another option, Lazarus said, is the GOP-dominated Congress could decide to use the Congressional Review Act as a weapon against environmental regulation. The law would allow the House and Senate, by majority vote, to overturn a rule by any federal agency and then prohibit that agency from reissuing the rule or creating a similar rule unless authorized by Congress.
That strategy was in full view in February when Congress overturned EPA’s rule implementing the “waste emissions charge” on methane emissions contained in the Inflation Reduction Act. The result, Lazarus said, is that though the IRA requires companies emitting methane to pay the charge, there are no regulations in place for that to happen, leaving the companies and the fee in limbo.
Congress might employ the same strategy to remove California’s ability to exceed federal regulations on vehicle emissions standards, which has not only allowed California to create the strictest standards in the country, but, once set, can be followed by other states.
The IRA itself is under attack as the administration tries to claw back funding in an array of programs intended to provide incentives for climate-friendly action. Like the moves that gutted USAID, choosing not to spend funds on congressionally approved IRA programs on climate change is illegal, Lazarus said. But the administration appears to be unconcerned with running afoul of the law and is pushing hard to bring change quickly.
“They don’t mind forcing the courts to act and litigation takes time,” Lazarus said. “The practical effect of a freeze and a contract violation is it takes time to undo it. In the meantime, money isn’t being spent. The contractors aren’t getting it. People’s salaries aren’t being paid. People have leases that aren’t being paid. Right now, it’s chaos among all those recipients around the country. And the Trump administration will keep changing the legal rationale, making it very elusive and just saying, ‘We’re pausing it,’ or ‘We have to study it more carefully.’ The practical effect is quite serious.”
In the end, Jenks and Lazarus agreed, it may be the effect on individual lives that does the greatest harm. Regulatory changes can be undone or rewritten and new regulations passed, but layoffs, reassignments, and hostile working conditions threaten to rob the agency of the scientific and legal expertise that has ensured continuity from administration to administration.
While some of the firings and other personnel steps undertaken by the new administration may be halted or reversed by the courts, people are leaving voluntarily because they are demoralized and have bills to pay.
“Many are leaving,” Lazarus said. “To lose not just the regulations, but potentially lose that career expertise, and the funding of the IRA, is potentially devastating.”
Fiona Hill and Lucian Kim.Photo by Grace DuVal
Nation & World
No quick end to Russia-Ukraine war, analysts say
Former national security official Fiona Hill says that much will depend on whether other European nations step up
Christina Pazzanese
Harvard Staff Writer
April 11, 2025
5 min read
Don’t expect U.S.-brokered talks that began last month to end the war between Russia and Ukrain
Former national security official Fiona Hill says that much will depend on whether other European nations step up
Christina Pazzanese
Harvard Staff Writer
5 min read
Don’t expect U.S.-brokered talks that began last month to end the war between Russia and Ukraine soon, analysts said during a discussion Tuesday hosted by the Davis Center for Russian and Eurasian Studies at Harvard.
Though Ukraine agreed to an unconditional ceasefire, Russia ramped up missile and drone attacks on Kyiv this week.
“We’re so far from a peace plan or a peace process,” said Fiona Hill, A.M. ’91, Ph.D. ’98.
Hill served from 2017 to 2019 as deputy assistant to the president and senior director for European and Russian Affairs at the National Security Council during President Trump’s first term. And she testified before Congress during Trump’s impeachment trial in 2019.
Russia President Vladimir Putin has no incentives to end the war, but plenty to engage in talks in hopes of normalizing relations with the U.S., agreed Hill and panelist Lucian Kim, a senior analyst for the International Crisis Group. The conversation was moderated by Evgenia Albats, Ph.D. ’04, a Russian political scientist and journalist who is currently a visiting scholar at the Davis Center.
Putin’s vision for a Russia reunited in some form with Ukraine and his willingness to let casualties mount make getting a lasting deal very limited, she said, as does a relatively inexperienced U.S. negotiating team.
Both Putin and Ukrainian President Volodymyr Zelensky know that Trump’s primary goal is to broker a peace deal, even if it doesn’t last or harms Ukraine, said Hill, now a senior fellow at the Brookings Institution’s Center on the United States and Europe and a member of the Harvard Board of Overseers.
“Trump is trying to force a peace deal [that] seems to be on Putin’s terms,” so that he can reset U.S.-Russia relations, something he tried to accomplish in his first term, she added.
Without intelligence and military support from the U.S., the “most likely” outcome for Ukraine is that it will have to cede territory to Russia. At this juncture, the notion that Ukraine could somehow retake Crimea and Donetsk is “almost hard to imagine,” said Kim, a former Moscow-based correspondent for NPR and Bloomberg.
But even a negotiated shift of territorial borders won’t be enough to satisfy Russia, he added. “Putin is not going to rest until Ukraine is subordinated to the Kremlin.”
The conflict in Ukraine has long been seen by Russia and its allies, China, Iran, and North Korea, as a proxy war with the U.S. How they react if the U.S. walks away from the conflict entirely is now the most important question, particularly for Europe, Hill said.
“This is now a European war, very clearly,” one that will test the region’s security and unity, she said.
Analysts agreed that Europe has more defensive capacity than it gets credit for. Many countries understand Russia poses a threat to their own individual security and have upped defense spending in recent years.
Others have been newly energized to beef up their fighting forces since Trump returned to office. But getting a coalition of individual European armies coordinated, trained, and fully prepared to step in to assist Ukraine if necessary will take time, perhaps more than the besieged nation has.
“The only hope that the Ukrainians have now is the Europeans somehow getting their act together,” said Kim.
Ukraine had the firm backing of President Joe Biden, Kim said, but even then the relationship between the two nations was far from perfect.
The Ukrainians had a very “high level of frustration” with the limits the administration put on what weaponry it shared and how it was to be used and the slow pace of deliveries. It was an overly cautious approach, they felt, driven by the fact that Biden and his team did not see the war as an existential threat to the U.S.
Also shaping the U.S. approach to military assistance in Ukraine, Hill said, was that the Biden administration’s first priority from the war’s earliest days was avoiding a nuclear World War III rather than doing whatever necessary to ensure that Ukraine defeated Russia.
During a recent trip to Ukraine, Kim said he never once heard Biden’s name mentioned and got the sense that few missed his administration. As early as last summer, there were signs Ukraine held out “a naive hope” about what might be possible in a second Trump term.
“People thought Trump, despite his record already in Ukraine during his first term, would somehow be able to rattle up the situation enough that there would be a better outcome than if the war simply continued in its present direction,” said Kim. But, he said, the Ukrainians have since been “disabused of those illusions.”
Bridget Kondrat (from left), Maggie Chiappetta-Uberti, Brooke Stanford, and Andrew Athanasian train along the Charles River for the 2025 Boston Marathon.Photos by Dylan Goodman
Campus & Community
Heartbreak Hill? These marathoners have seen worse.
Christy DeSmith
Harvard Staff Writer
April 11, 2025
9 min read
Loved ones inspire College runners to go the distance against disease
For t
Bridget Kondrat (from left), Maggie Chiappetta-Uberti, Brooke Stanford, and Andrew Athanasian train along the Charles River for the 2025 Boston Marathon.
Heartbreak Hill? These marathoners have seen worse.
Christy DeSmith
Harvard Staff Writer
9 min read
Loved ones inspire College runners to go the distance against disease
For two years, grief left her body feeling like a pressure-cooker.
“It wasn’t until my junior year that I discovered something that really helped with the release of my emotions,” said Brooke Stanford ’25, who lost her mother, Andrea, to pancreatic cancer two weeks before arriving on campus as a first-year in 2021.
“The one thing that really helped was running.”
Now Stanford is using the sport to honor her mother and lift other families facing the disease. She’s been training for this year’s Boston Marathon while soliciting donations for Project Purple, a nonprofit dedicated to fighting pancreatic cancer and supporting patients. Every year, the Boston Athletic Association partners with a set of charities, which in turn recruit marathoners to raise money ahead of race day.
Stanford won’t be the only College runner hitting the 26.2-mile course for a loved one on April 21. Each of these students is vying for a strong finish — and a fundraising haul for a cause close to the heart.
‘I was just so excited I got to do this’
Stanford with her mother, Andrea.
Stanford discovered Project Purple last summer while browsing a list of approved charities for the marathon.
“I knew I would want to run for some sort of cancer research organization, but I didn’t think that there would be one so fitting to what I had been through,” she said. “After that, I made it my No. 1 mission to get a spot on the Project Purple team.”
The trouble was, the odds were on par with getting into Harvard.
“I had just under 150 applications for five spots,” said Project Purple program director Vin Kampf.
Stanford, a Dunster House resident and applied math concentrator, soon found herself swept into phone calls and interviews with Kampf and the nonprofit’s other top brass.
“You would think I was applying for a job at an investment bank,” she said. “A lot of people think the hardest part about running for a charity is raising the money. But the hardest part is 100 percent getting a spot on the team.”
The final step was a formal presentation of her fundraising plans to Project Purple last fall. “I spent a full week putting together this very detailed PowerPoint and Excel,” recalled Stanford, who vowed to raise $50,000 by soliciting individual donations and hosting special events. “I spent way longer doing that than on any assignment Harvard has ever given me.”
A week later, she received the good news in a tearful call with Kampf. “I was just so excited that I got to do this — and do it for my mom,” she said.
The first-time marathoner, who dons purple leggings for every training run, has continued giving it her all. She surpassed her $50,000 pledge nearly two months ago and currently ranks in the Top 10 of Boston Marathon fundraisers this year. According to Kampf, she also ranks among Project Purple’s most successful charity runners ever.
“In some ways, I feel like I found my life’s purpose,” Stanford said. “I want to work more with Project Purple. I want to do more to make a difference. I want to help end pancreatic cancer.”
‘Just imagine if this was the Boston Marathon’
Athanasian with friends including Grace Taylor (right).
At first, Grace Taylor ’25 didn’t tell her friends about her cancer diagnosis. She was too busy working as a peer adviser for incoming first-years.
“I wanted to be the best peer adviser I could be,” said Taylor, a rising sophomore at the time. “I knew that if I let my own stuff in, I wouldn’t be able to serve the entryway very well.”
When she texted her pal Andrew Athanasian ’25 a few days later, he too was a bit occupied.
“I was walking across the river to go work out when Grace texted, ‘Hey, can we talk?’” Athanasian recalled. “I was like, ‘Is it important?’ And she replied, ‘No, not really.’”
Taylor broke the news later that day. Athanasian immediately stepped up, becoming a pillar during his friend’s treatment for an aggressive form of thyroid cancer. Not least, he and Taylor’s Quincy House roommate, Amy Wotovich, made countless runs to BerryLine for (among other things) throat-soothing ice cream. With the help of them and her parents, Taylor said, she persevered without dropping out for the semester.
Athanasian, an econ concentrator who lives in Lowell House, joined Taylor and her family last fall at the Mass General Brigham Eversource Cancer 5k, a benefit for the oncology practice that saw Taylor through two surgeries and radioactive iodine treatment.
“Seeing how Grace and her family responded to that 5k,” Athanasian recalled, “I found myself saying: ‘Just imagine if this was the Boston Marathon.’”
After nabbing a spot on the Mass General Marathon Team, the first-time marathoner has made that vision a reality. Athanasian aims to raise $10,000 for the hospital’s pediatric oncology unit, with part of the proceeds earmarked for the adolescents and young adults cancer program that saw Taylor through treatment into remission.
“I’m running for Grace but I’m also running for everyone who didn’t make it,” emphasized Athanasian, remembering a friend from his Long Island hometown killed by brain cancer at age 17. Athanasian, a committed Catholic, has inscribed his Asics with references to scripture as a reminder of his inspiration. (Hebrews 12:1, on his right, feels tailor-made for the modern charity runner.)
On race day, Taylor hopes to glimpse her friend from the celebration hosted by Mass General, a long-standing fixture at Mile 20 — just before the course crests Heartbreak Hill.
“That’s the darkest part of the course,” Athanasian said. “But they’re bringing out all the pediatric oncology patients to cheer us on. How can you not become Usain Bolt after seeing those kids?”
‘The opportunity to call upon her strength’
Kondrat with her grandmother Cleida Buckley.
Every Sunday, Cohasset, Mass., native Bridget Kondrat ’26 would attend Mass with her large extended family. Then everyone would head over to her grandparents’ place and spend the day together.
“We have always been so close,” said Kondrat, who counts three siblings and 18 cousins. “And my Nana was really the heart of that.”
For 14 years, Kondrat’s maternal grandmother, Cleida Buckley, fought multiple myeloma with the help of Dana-Farber Cancer Institute. Through it all, the 5-foot-2 powerhouse maintained her status as the family’s hostess and connector.
“She just kept showing up for us,” Kondrat said.
Watching the marathon became another family tradition after Kondrat’s mom, Liz, ran in 2000, and Buckley proved a memorable presence from her perch on Heartbreak Hill.
“She was so freaking cute, just sitting there in Newton Centre with her little beach chair,” Liz said.
That’s why training for the 2025 event with the Dana-Farber Marathon Challenge team struck Kondrat as the perfect way to honor her grandmother, who died in 2022.
“Running with Dana-Farber gives me the opportunity to call upon her strength,” said Kondrat, who hopes to raise $10,000.
The Harvard-Radcliffe rower and Eliot House resident has ambitious goals for her second marathon. Charity runners can run Boston without meeting the race’s strict qualifying times. But the economics concentrator hopes to best the event’s official 3 hour and 25-minute cutoff (with an average pace of 7:49 per mile) for women ages 34 and younger.
Kondrat, who started running with her mom in fourth grade, has been following an ambitious training program complete with speed workouts, intervals, and long runs at her target marathon pace.
“I biked next to her last week when she ran 12 miles,” Liz said. “She was doing 7:30s the whole time!”
Keeping up the regimen has been a challenge for a full-time student-athlete and part-time fundraiser, Kondrat said. But it’s nothing compared with the marathon battle Buckley endured.
“Whenever I start to complain or lose motivation,” Kondrat said, “I just think about everything I watched my Nana go through.”
‘She started showing me her medals’
Chiappetta-Uberti with her mother, Lainee.
In seventh grade, Maggie Chiappetta-Uberti ’26 came home feeling discouraged after her first track practice. She was exhausted. She was sore. All she wanted to do was quit.
“My mom Lainee sat me down and right away started instilling me with confidence,” Chiappetta-Uberti recalled. “She started telling me about the records she set in middle school and high school. She started showing me her medals.”
That inspired Chiapetta-Uberti to stick with it. “I’m so grateful to her for pushing me to continue,” said the Kirkland House resident, who competed in cross-country and track through high school.
Her mom, Lainee Uberti, was diagnosed with early onset Alzheimer’s at 58. “She immediately started walking four miles every day,” recalled Chiappetta-Uberti, who was in ninth grade at the time.
More than six years later, Uberti is still religious about her daily jaunt. “Getting out there and running or walking,” she said in an interview, “that’s what keeps us going.”
Once again, that strength has inspired her daughter to tackle a big challenge. Chiappetta-Uberti is training for her first marathon while raising funds for the Alzheimer’s Association. Each member of Team End ALZ is supposed to bring in a minimum of $10,000. But the neuroscience concentrator set the loftier goal of $26,200 — or $1,000 per mile.
As part of her efforts, she’s also populating a TikTok feed with training videos, Alzheimer’s awareness, and tributes to Uberti.
“It’s so special that Maggie is going the extra mile — no pun intended — to raise awareness, raise money, and put her heart into representing our family,” said Chiappetta-Uberti’s other mom, Laura Chiappetta. Both parents will travel from their home in Los Angeles to cheer their daughter’s 26.2-mile debut.
The punishing race feels like an appropriate gesture when her mom is dealing with an incurable disease like Alzheimer’s, Chiappetta-Uberti said. “I want her to know there’s support for her — she’s not facing this alone.”
Photos by Veasey Conway/Harvard Staff Photographer
Campus & Community
Cutting drug costs, embracing aging, demystifying AI — and more research ideas
Anna Lamb
Harvard Staff Writer
April 11, 2025
7 min read
8 graduate students pitch their work in Harvard Horizons talks
At Harvard, thousands of scholars are working to advance knowledge on a wide array of topics. Eight students are sele
Cutting drug costs, embracing aging, demystifying AI — and more research ideas
Anna Lamb
Harvard Staff Writer
7 min read
8 graduate students pitch their work in Harvard Horizons talks
At Harvard, thousands of scholars are working to advance knowledge on a wide array of topics. Eight students are selected each year to workshop ways to bring that knowledge from the University to the wider world through Harvard Horizons.
Now in its 12th year, the program invites doctoral candidates to share their work in a one-night academic symposium. Students receive one-on-one mentoring to hone their presentation skills and research ideas.
“It is crucial that both faculty and students are able to communicate and connect with the broader world,” said Karen Thornber, the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning. “These multimodal skills are foundational, both for engaging students in the classroom and for ensuring that research which has the potential to contribute significantly to the well-being of all is both accessible and impactful to a wider audience.”
Ancient structures are not as set in stone as we once thought. Alarcón Robledo is trying to better understand the histories of tombs in North Saqqara, Egypt, using 3D modeling and a process called photogrammetry — mapping structures onto archaeological sites with archival photography and software. He’s found that tombs changed over time, with additions and reconstructions, from places purely for funeral services to sites of ritual practices and community gatherings.
“Buildings are like people, and writing about their history is very much like writing their biography,” he said. “In our lives, there may be many moments which are representative of our identities … but even freezing one moment of everyday of our lives would not be representative.”
Getting older can be beautiful, says Braslavsky. Her talk centered around what scholars can learn from older female poets, including how to embrace aging instead of succumbing to the narrative of decay and decline.
“While the cultural zeitgeist tells us to fear aging, aging is more a part of the human experience than ever before,” she said.
Her work in particular focuses on three Slavic poets — Elizabeta Mnatsakanova, Bohumila Grögerová, and Krystyna Miłobędzka — who wrote and created into their later years.
“These women show us through their work that time can be filtered through our perceptions, that time can be measured as much emotionally as it can be empirically,” Braslavsky said.
Silver, according to Campbell, may be good for more than jewelry. His work is attempting to use silver in a chemical process that would make the production of pharmaceuticals a fraction of the current cost. The trifluoromethyl group is essential to many modern drugs, but it can be hard to synthesize. Using photochemistry, Campbell has been working to utilize trifluoroacetate as a trifluoromethyl source — a notoriously hard process.
To do this, he’s utilizing a special type of silver (Ag²⁺) — a highly reactive form of the metal that can be recycled and reused to not only cut costs but potentially also make strides in sustainability.
“At the outset of my Ph.D., very few Ag²⁺ compounds had ever been made before. But in this absence of knowledge, in this lack of precedence, I saw opportunity, and I seized it by devising a new synthetic strategy toward isolating large quantities of silver compounds,” Campbell said.
Before there were spreadsheets, there were khipus. Twisted twine with series of knots, khipus were the ancient Inca’s alternative to written script. They were used to record data, including census counts, taxes, and maybe intricate narratives and songs.
FitzPatrick has been studying a collection of 33 khipus from cliffside tombs at Laguna de los Cóndores in Peru to better understand the people who made them.
“I decided to put the process on its head, working backwards to understand how khipus were made, who made them, and what this can tell us about their use,” FitzPatrick said.
Part of this process, he said, has been to become a khipu-maker himself. During his presentation, FitzPatrick distributed a homemade khipu to each member of the audience.
The ancient Greek poet Sappho has long been considered by scholars to have been lost to time, only to be rediscovered in the late 19th century when fragments of papyrus containing her poetry were unearthed in Egypt. But Horgan says she was never really lost.
“She has been continually present in poems and plays, in sculptures and statues, and in the minds of the readers who have imagined her again and again and again, regardless of the presence or absence of her poetry,” Horgan said.
Horgan’s work is focused on dispelling the myth that the work of Sappho — a famously queer poet — was purposely oppressed. In reality, she said, Sappho and her queerness have been present in countless works of scholarship and art since her life in the time before Christ.
“My hope is that this work provides not only narratives of queer suppression, but queer survival. Sappho did not survive in spite of her queerness, but in fact, because of queerness,” she said.
Courts, key institutions in democratic societies, can both help and hurt democracy, according to O’Donohue. The Ph.D. candidate, who witnessed a military coup attempt while working for the U.S. State Department in Istanbul, said in his talk that this is particularly apparent in places like Turkey, as well as Israel and even the U.S. Israel and Turkey, according to O’Donohue, exemplify opposite ends of the “judicial power-sharing” spectrum — or the need for cross-partisan compromise to appoint judges to the country’s highest courts.
“I came to Harvard because I had this problem I needed to solve,” he said. “Why do courts defend or undermine democracy in particular by upholding legal constraints of powerful political leaders?”
Are we using AI wrong? Raux says we are. According to his research, humans project their own thinking onto artificial intelligence, leading us to miss out on what the tech can really do for us.
“We need to make sure that as humans, we can fully harness the potential of AI,” Raux said.
Conducting experiments using chatbots, Raux had the AI answer questions about parenting advice. His aim was to show that human intelligence is vastly different than artificial intelligence, and that what makes something difficult for humans may be different from AI and vice versa.
“But do people realize this when interacting with AI?” he asked.
Ultimately, Raux hopes that his work will help both researchers and users better harness the technology’s power.
Venturo-Conerly has a lofty goal: to bring mental healthcare to every young person across the world. She’s starting in Kenya. Building on work she started as an undergrad with fellow Harvard alumni Tom Osborn, Venturo-Conerly has been programming mental health services for Kenyan youth through the Shamiri Institute. Named for the Kiswahili word meaning “thrive,” Shamiri uses a tiered system of laypeople, supervised by mental health professionals and experts, to deliver counseling and academic support to Kenyan students. Along with mental health, their work focuses on academic, financial, and social well-being.
“Instead of focusing on psychopathology, it circumvents stigma by focusing on positive concepts, growth mindset, gratitude and values, affirmations, all of which are research-backed interventions theorized to produce an upward spiral of change in beliefs and behaviors,” Venturo-Conerly said.
Shamiri is in its sixth year of operation, and Venturo-Conerly and Osborn continue to study its impacts.
Mayors of Brownsville, Texas, John Cowen (left) and Ciudad Juárez, Mexico, Cruz Pérez Cuéllar (right), join moderator Diane Davis. Veasey Conway/Harvard Staff Photographer
Nation & World
Separated by a border, but with fates entwined
Mayors from U.S., Mexican cities flanking divide compare notes on immigration, national leadership, tariffs
Christy DeSmith
Harvard Staff Writer
April 10, 2025
5 min read
Mayors from U.S., Mexican cities flanking divide compare notes on immigration, national leadership, tariffs
Christy DeSmith
Harvard Staff Writer
5 min read
From afar, the 2,000-mile U.S. border with Mexico appears as a hard economic, political, and cultural boundary. But mayors of cities that flank the divide have a different view.
“We’re a binational community,” said Mayor Carlos Peña Ortiz, HKS ’20 of Reynosa, Mexico, which mirrors McAllen, Texas, across the Rio Grande. “We share values; we share businesses; we share religion; we share families; and we’re basically just divided by a river.”
Three borderland mayors appeared at a recent symposium on U.S./Mexico relations, hosted by the David Rockefeller Center for Latin American Studies. These leaders, currently focused on protecting their local economies, spoke to issues related to immigration, tariffs, and recent presidential transitions in both countries. They also testified to their interconnected fortunes.
“Historically, Brownsville has been very affected by the Mexican peso,” said Mayor John Cowen Jr., who leads the city of 190,000 at Texas’ southernmost tip. “If there’s a big devaluation, our local economy just crashes.”
Moderator Diane Davis, Charles Dyer Norton Professor of Regional Planning and Urbanism at the Harvard Graduate School of Design, kicked off the event by asking how things have changed in light of federal transitions of power. Mexican President Claudia Sheinbaum took office in October, just three months before President Trump returned to the White House in the U.S.
All three mayors described dramatic decreases in migrant flows, with those from Mexico also noting reduced crime. Peña Ortiz estimated a “95 percent” decrease in migrant traffic over the past two months. The second-term mayor couldn’t be physically present at the session as he had to rush home due to flash flooding in the area. Instead he sent a video of himself answering Davis’ questions.
“We’ve seen a very significant drop in most migrant groups,” said Peña Ortiz, who highlighted the appearance of Russian and Ukrainian passports until recently. “Our migrant camps were full for the last eight, nine years. We usually had around 16,000 to 20,000 migrants in our community, and nowadays we have close to 700. … And for the last month, we have not seen a lot of gunfights. Violent crime has dropped significantly.”
“We share values; we share businesses; we share religion; we share families; and we’re basically just divided by a river.”
Mayor Cruz Pérez Cuéllar of Ciudad Juárez, across the river from El Paso, Texas, praised the Sheinbaum administration for helping his city of 1.6 million bolster shelter capacity ahead of promised deportations by U.S. Customs and Border Protection.
“For the first time since I was born in Juárez,” he said, “I see a federal government that is concerned about what is going to happen.”
Cowen, elected in 2023 for the nonpartisan position, observed the very opposite. More than 50,000 migrants from 31 different countries passed through the city’s port of entry during his first month in office, he said. “We were able to manage that through a combination of relationships with our federal government, with our NGOs.”
But now he worries about a future influx given the currently shifting state of federal funding. He voiced particular concern over the Federal Emergency Management Agency’s Shelter and Services Program, which helps support local efforts to house migrants.
“But other than that type of funding, we’re looking at cuts to our health programs, our ability to respond to infectious disease,” he added, noting that Brownsville has dealt in the past with Zika and other mosquito-borne illnesses. Also key to the city’s budget, he said, is federal transit funding.
Tariffs proved a top concern, with the Mexican mayors braced for negative impacts. Peña Ortiz worried what border taxes portend for the future of cross-border cooperation on everything from workforce training to preserving water quality.
“Historically, we’ve been working together with programs like NADBank,” he said, referring to a program established by the U.S. and Mexican governments in 1994 to finance critical environmental infrastructure. “But if there’s no collaboration from the U.S., what will happen long-term with water resources here in the border communities?”
Ciudad Juárez investors are waiting for U.S. tariff policy to stabilize, said Pérez Cuéllar, who just visited Taiwan to bolster relations with business leaders there. “The big problem is that huge companies are waiting,” he said. “I talk to them a lot, and they say, ‘Well, we want to keep investing but we have to wait.’”
On the U.S. side, Cowen acknowledged tariffs as a “headwind” for new business ventures. But the city is still benefiting from initiatives launched in recent years. Currently underway at the Port of Brownsville is a massive gas liquification and export terminal, due for completion by decade’s end. New SpaceX facilities are also under construction in the area.
“That’s $40 billion in investments” for a city currently worth $10 billion, emphasized Cowen, a sixth-generation resident intent on lowering the city’s historically high rates of poverty. He was proud to cite a recent Harvard study ranking Brownsville as the top U.S. city for improving intergenerational mobility.
Arts & Culture
How to dance like somebody’s watching
Sy Boles
Harvard Staff Writer
April 10, 2025
3 min read
Choreographer offers tips on finding release: ‘Ain’t nobody concerned if you look good’
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
Jeffrey L. Page is an opera and theater dir
A series of random questions answered by Harvard experts.
Jeffrey L. Page is an opera and theater director of both classical and contemporary works and a lecturer in Harvard’s Theater, Dance & Media program. He was the co-director of the revival of the musical “1776” and has won an MTV Video Music Award for his work with Beyoncé.
We all want to be seen.
Ralph Ellison wrote this book, “Invisible Man,” which was essentially about Black people. As I walk through my life, many a time, if I’m not already invisible, I have to make myself invisible so that I’m not disrupting a process or shaking the boat. I have to become invisible in order to adhere to respectability politics. But dance is all about being seen. How can the narrative that I’m putting into space, with my body, be read like a book? I believe dancing can do that. Dance as if we’re all watching. What do you want us to see?
It’s as if I’m accessing a reservoir of information that has been locked away.
Imagine you’re writing an essay. You’re working on this sentence for maybe eight hours. You’re trying to put the words together. The moment you find that sentence, it’s like, ‘Yes, that’s it. That’s the sentence. That’s the paragraph. That’s the story.’ That’s what it feels like to go from a non-dancing body to a dancing body. It’s cathartic. It’s as if I’m accessing a reservoir of information that has been locked away.
In Mali in West Africa, they have a practice known as djine foly. I’m sure people have heard of djinn, the Islamic mystic or spiritual guides; we might also know them as genies. Those djinn exist in Malian culture, too. Djine foly means the dancing space of the djinn. The dancers dance themselves into a trance-like state. When they have achieved this trance-like state, they become happy. An explosion of feeling comes upon them. In the Black community, we call it catching the holy ghost. It’s a spiritual thing. The way we unabashedly dance with abandonment and intention, it’s a spiritual phenomenon.
Students who take my class enjoy the class because I scream and I holler and I get them to release all of the stuff that’s sitting on their shoulders and sitting on their heads. Sometimes you just gotta shout to get the thing off of you in order to relax! Ain’t nobody concerned if you look good! Just dance!
Sometimes our logical mind is so strict and unmoving that, baby, it just needs to be a shout to get the logical mind to release itself so I can find that trance and attain my djinn.
Arts & Culture
Harvard archivists’ favorite finds
Illustration by Liz Zonarich/Harvard Staff
Tenzin Dickie
Harvard Library Communications
April 10, 2025
8 min read
Library staff pick objects that tell story of both University, America for ‘Inside Out’ exhibit
A handwritten note from former President John F. Kennedy to his Harvard College classmates. A 1905 letter from W.E.B. Du Bois
Library staff pick objects that tell story of both University, America for ‘Inside Out’ exhibit
A handwritten note from former President John F. Kennedy to his Harvard College classmates. A 1905 letter from W.E.B. Du Bois to his mentor, Albert Bushnell Hart, discussing race relations in America. A screen capture of The Harvard Crimson from March 2020 with the headline: Harvard President Bacow Tests Positive for Coronavirus.
Drawn from the Harvard University Archives, these items — on display through April 30 in the “Archives Inside Out” exhibit — tell a story of Harvard that is also a story of America. They also showhow items enter the archival record and become part of Harvard, and American, history.
“We wanted to demystify the work that we do and make it more accessible to the public,” University Archivist Virginia Hunt said of the goal of the exhibit. “The items on display celebrate Harvard’s institutional and community history while showcasing the unique expertise of our dedicated staff.”
Exhibit curators invited their colleagues to submit their favorite items, with an eye to surfacing pieces of history that shed a light on the nature of archival work. Staff were asked: What stands out to you and why? When you go home to your family and you talk about your day, what are you excited to talk about? What is your special find from the collections?
“This was a unique exhibition model and we wanted to get input from all our staff,” said Sarah Martin, Associate University Archivist for Community Engagement. “From the submissions, we selected items that not only tell compelling stories but also best represent the form and function of the University Archives.”
Below are select items from the exhibit, with accompanying text from the archivist who chose it. The full exhibit is open to the public and on display in Pusey Library’s Lammot du Pont Copeland Gallery through the end of the month.
In fall 2013, I was an enthusiastic and fresh-faced new archivist on the hunt to answer a reference question about a member of the Harvard College Class of 1940. Coming up short, I cast my net wider and reviewed materials related to the class’s “correspondence, photographs, questionnaires.” While this broader search did not answer the question, I found instead a previously unknown letter — a draft, really — from John F. Kennedy to his class on this colorful letterhead.
It was my first professional “find” but more than that — it offers a light-hearted, warm, and amusing insider’s view on a complex historical figure.
— Pam Hopkins, Head of University Archives Reference Services
This image depicts “women astronomical computers” who were tasked with cataloging stars, studying stellar spectra, and counting galaxies, among other responsibilities, using the observatory’s glass plate negative collection. I find it compelling as it illustrates the invisible labor that continues to be done by women in the workplace. The description of the women as “computers” is both accurate in this context and foretelling of the invisible labor that supports much online content and activity today.
My own work takes place mainly in the faceless digital environment of email, databases, and spreadsheets, and I sometimes think of how close the “women computers” are to our world in both time and practice.
This letter comes from the personal archive of Albert Bushnell Hart, professor of history and government at Harvard from 1886 to 1924. This collection was recently fully digitized, and it was my responsibility to prepare it for digitization.
The first folder in the first box I opened when I began this work contained letters Hart received in reaction to his study of race relations in the U.S. South, including this letter. These letters provide an example of the wide range of individuals who interacted with Hart’s ideas, and the diversity of ideas among them. It contains correspondence from prominent figures such as W.E.B. Du Bois and Booker T. Washington, as well as members of the public who wanted to share with Hart their thoughts on his work.
Thomas Hill (1818-1891) was president of Harvard University from 1862 to 1868. He was also a Unitarian minister, mathematician, scientist, educator, and Harvard lecturer. Throughout his life, Hill retained an interest in discovery and improvement. Hill’s perpetual calendar, a paper instrument with a rotating wheel chart, features calculations to look up any New Year’s Day from 1583 to 1996, illustrating his talents as an inventor and a devisor of scientific instruments.
I chose this item because it illustrates a Harvard president delving deeper into scientific pursuits rather than just education. When processing this collection, I was fascinated by its intricate design and historical significance. I often encounter materials outside of traditional paper records in my work, such as 3D artifacts, which provide unique storage and description challenges.
Here is a screen capture of one of our online collections documenting Harvard’s initial responses to the COVID-19 pandemic. I used digital tools to capture (or “crawl”) this online issue of the student newspaper The Harvard Crimson in March 2020 as part of my regular support of the Harvard University Archives’ robust web archiving program. It provides a snapshot of an uncertain and unprecedented time for the Harvard community and the world.
— Sean Crawford, Collection Development and Records Management Coordinator
Sketches from the Harvard Lampoonwas the first donation that I personally accepted into the Harvard University Archives. As the Collection Development Archivist, part of my role is to recommend what donations should be accepted into the Archives, especially when it comes to Harvard student groups. The other part of my role is to prepare accepted donations to be added to our collection. The Harvard Lampoon is one of the oldest student groups and student publications in Harvard’s history. This special edition of the publication perfectly represents the intersection of the different parts of my role at the Archives.
I happen upon wonderful things as I go through newly acquired collections — such as this letter from the poet Seamus Heaney to Harvard English Professor Helen Vendler (who recently died just before her 91st birthday), part of a recent accession of Vendler’s personal archive in fall 2023. As a collection development archivist, I prepare new collections for research use, inventorying the contents and housing materials safely for long-term storage.
This letter was tucked inside a folder of “first day handouts” for Vendler’s freshman poetry seminar on Walt Whitman. In it, Heaney lightheartedly describes a medical emergency he experienced while visiting the Irish playwright Brian Friel, ending with reassurance to his friend, and frustration at being told not to “do” anything.
— Heidi Horner, Collection Development & Records Management Services Assistant
I became an archivist to ensure that archives are reflective of the world’s diverse history, people, and cultures. To that end, I primarily process collections related to under-represented or marginalized communities for Harvard Library’s Equity, Diversity, Inclusion, Belonging, and Antiracism Digitization Program. The resulting digitized collections are made publicly available online.
My favorite collections are the mundane ones. Personal letter collections, like the one this letter comes from, offer a little window into someone’s life at a certain time. This letter was written by African American Harvard student Ragan Henry ’56 to his Jewish friend and roommate, Joseph Levow Steinberg ’56, during summer break. The letter touches on racial discrimination at work, dating, and the difficulties of living in a “hick town.” But really, this letter between friends in the 1950s is not so different from text messages you’d see between college friends today.
This volume contains personal accounts of nearly 20 Harvard students circa 1942 who wanted to document the reasoning behind their opposition to military service in World War II. Working with then-University Archivist Clifford K. Shipton, they deliberately and permanently placed this volume within the Harvard University Archives’ collections. They wanted their experiences, which ran counter to many of their peers’, not to be forgotten.
My daily work is to connect researchers to primary sources vital for their academic pursuits. This manuscript came to my attention as pacifism during World War II has been a longtime personal interest. It is also a vivid reminder that archives act as a place of memory.
“Archives Inside Out” was curated by Emily Atkins, Ed Copenhagen, Hannah Hack, Virginia Hunt, Juliana Kuipers, Sarah Martin, Jehan Sinclair, and Caroline Tanski of the Harvard University Archives.
Health
Is dining with others a sign of happiness?
Getty Images
Jacob Sweet
Harvard Staff Writer
April 10, 2025
4 min read
Shared meals may be a more reliable indicator of well-being than income, Kennedy School researcher says
People who eat more meals with others tend to be more satisfied with their lives and are more likely to express positive emotions, according to a study published in
Shared meals may be a more reliable indicator of well-being than income, Kennedy School researcher says
People who eat more meals with others tend to be more satisfied with their lives and are more likely to express positive emotions, according to a study published in the annual World Happiness Report. According to the finding’s authors, sharing meals is as predictive of happiness as income or employment status — across ages, genders, countries, cultures, and religions.
It may be a problem, then, that the Bureau of Labor Statistics’ American Time Use Survey found that Americans are spending more and more time dining apart, numbers the authors cite in their study. “In 2023, roughly 1 in 4 Americans reported eating all of their meals alone the previous day,” the study said, “an average increase of 53 percent since 2003.” This trend holds across all age groups, with the most dramatic drop among young people.
“It’s just surprising to me that this increase would be so clear and so severe,” said Micah Kaats, a doctoral student in public policy at Harvard Kennedy School who co-wrote the report.
While the study shows a strong correlation between the number of shared meals and happiness, it does not state whether sharing meals causes happiness or whether happy people tend to share more meals. “In all likelihood, I would be willing to put money on both being true,” Kaats said, “but which of those factors is stronger is definitely a task for future research.”
The correlation itself is an important development for the field, according to Kaats, in part because happiness is hard to measure. When researchers ask someone to rate themselves from one to 10 on a happiness scale, Kaats says, it’s hard to pinpoint what a one or 10 might mean for any given person on a single day.
Though these subjective measures can be valuable to social scientists and policymakers, researchers often use income, insurance rates, and other factors that have shown strong correlational links to well-being as proxies. But these factors themselves are often hard to measure. “A lot of people don’t want to report their income,” Kaats said. “Those who do want to report their income are a select group.” From there, it’s difficult to tell the accuracy of what’s being reported, the exact type of income one might report (Pretax? Household? Posttax?), and how incomes can be compared between countries and over time.
Compared to these often-used variables, the number of shared meals is relatively clear-cut: “Yesterday, did you eat lunch or dinner with someone you know?” Kaats hopes that the question will find a use among other objective indicators linked to social connection — such as density of civic organizations or the number of political groups per county — that are used to gauge amorphous concepts like happiness and social trust.
In future research, Kaats hopes to tease out whether people become happier when they share more meals. But regardless, Kaats believes that the correlation between shared meals and happiness is important on its own. “If I want to know about your well-being, it’s much more informative for me to know how many meals you ate with other people in the last week than how much money you make,” he said, “so whatever the causal dynamics are, that seems important and interesting and worth further study.”
As researchers and policymakers contend with worsening mental health and increasing social isolation, shared meals could be both an important indicator of well-being and a source of policy intervention.
“We can’t solve every problem at once,” Kaats said, “but if we can get people to share more meals with each other, and that would improve people’s well-being, it’s a good place to start.”
Health
Researchers ID genetic disorders that can be treated before birth
Timely detection could reduce morbidity, offers opportunities for early intervention
Mass General Brigham Communications
April 9, 2025
3 min read
A new study identifies nearly 300 genetic disorders that can be treated during pregnancy or in the first week of life, forming the basis for a “treatable fetal findings list” that c
Researchers ID genetic disorders that can be treated before birth
Timely detection could reduce morbidity, offers opportunities for early intervention
Mass General Brigham Communications
3 min read
A new study identifies nearly 300 genetic disorders that can be treated during pregnancy or in the first week of life, forming the basis for a “treatable fetal findings list” that could be offered to pregnant patients.
The findings could improve the diagnosis of genetic conditions in pregnancy and enhance the treatment options available for fetuses that have these conditions, according to researchers at Harvard Medical School, Harvard-affiliated Mass General Brigham, and Duke University School of Medicine. The study’s results are published in the American Journal of Human Genetics.
“These conditions are actionable — meaning that, empowered with diagnostic information, we can intervene early and improve outcomes.”
Nina Gold, Harvard Medical School
“We saw a critical gap in prenatal care and an opportunity to define the genetic disorders that are treatable during this time,” said senior author Nina Gold, director of Prenatal Medical Genetics at Massachusetts General Hospital and an assistant professor of pediatrics at HMS. “These conditions are actionable — meaning that, empowered with diagnostic information, we can intervene early and improve outcomes.”
Over the past decade, genomic sequencing has become a vital tool to help inform prenatal diagnoses. Genomic sequencing tests, combined with family history, can help identify genes responsible for ultrasound abnormalities. They can also uncover incidental findings that may predispose a fetus or newborn to serious but treatable conditions, such as a heart condition that can be treated with medications or a gastrointestinal disorder that can be managed with fluid and electrolyte therapies. The research team set out to develop a list of these treatable conditions so that patients can be offered the choice of receiving this kind of information.
Through a literature review, the authors identified a total of 296 genetic conditions, ranging from disorders with emerging fetal therapies to those where immediate postnatal treatment can prevent irreversible harm. The authors emphasize that timely detection of these conditions could reduce morbidity and mortality, offering families unprecedented opportunities for early intervention.
“One of our goals is to expand the options that a family has during pregnancy,” said Jennifer Cohen, the lead author on the study and a medical geneticist at Duke University Hospital. “These lists of genes are meant to provide the possibility of early intervention, which in some cases may change the natural history of the disease.”
Despite its potential, this initiative comes with challenges. The researchers outline ethical considerations and acknowledge that patients may feel overwhelmed by the amount of information they are offered. They also highlight the importance of engaging medical geneticists, obstetricians, and ethicists to address these complexities.
“Our goal in creating this targeted list of treatable fetal findings is to improve care, but we are sensitive to the challenges for physicians, genetic counselors, and patients when it comes to navigating new health information during pregnancy or immediately after the birth of a child. This is why it’s so important to work as a care team to empower our patients and provide them with the clearest information possible,” said Gold.
The research described in this story received funding from the National Institutes of Health.
Susan Murphy (left) and Ziping Xu. Photo by Grace DuVal
Science & Tech
Like having a personal healthcare coach in your pocket
New apps for cancer patients, cannabis users, others make use of algorithms that continually customize support
Anne J. Manning
SEAS Communications
April 9, 2025
5 min read
Cancer patients who undergo stem cell transplantation face a long recovery, requiring m
Like having a personal healthcare coach in your pocket
New apps for cancer patients, cannabis users, others make use of algorithms that continually customize support
Anne J. Manning
SEAS Communications
5 min read
Cancer patients who undergo stem cell transplantation face a long recovery, requiring medications with debilitating side effects and support around the clock. It’s a difficult experience, with studies showing that more than 70 percent of patients don’t adhere to drug regimens.
Statistician Susan Murphy spends her days trying to help people suffering from such challenging maladies. The Mallinckrodt Professor of Statistics and Computer Science and associate faculty at the Kempner Institute and her team address healthcare needs not through medicine, but by mobile apps.
Murphy’s lab specializes in creating sophisticated computational instructions known as reinforcement learning algorithms, which form the technical backbone of next-generation programs to help people stick to a medication protocol, for instance, or regular tooth brushing, or reducing cannabis use.
And if this sounds like one of those ubiquitous apps that tracks steps or counts calories, think again.
“If you’ve ever downloaded a health app, those tend to be pretty dumb,” Murphy said. “For example, you’ll get a physical activity app, you’ll sprain your ankle, and it’ll continue to tell you to go for a walk.”
“If you’ve ever downloaded a health app, those tend to be pretty dumb.”
Susan Murphy
Using advancements in artificial intelligence and sensing technologies to move beyond one-size-fits-all interventions, the lab’s apps are capable of real-time personalization, meting out psychological rewards, and in some cases, leveraging social networks to help users stick to goals.
This approach is called “just-in-time adaptive intervention” because it aims to provide support at just the right time by registering changing needs and contexts.
Currently the Murphy lab is working with software engineers, cancer clinicians, and behavioral scientists to develop an app for stem-cell transplant patients and their primary caregivers, usually parents.
Health management, especially for the sickest, typically requires involvement of others. For instance, up to 73 percent of family-care partners have primary responsibility for managing cancer-related medications.
The researchers are in the early stages of developing the algorithm, to be deployed in a first-round clinical trial this year by collaborators at the University of Michigan and Northwestern University. The trial, called ADAPTS HCT, will focus on adolescent and young adult patients who’ve had stem-cell transplants in the 14 weeks post-surgery.
The algorithm will inform sequential decisions, including when and whether to send motivational prompts to the patient, and whether to send messages and reminders to both patient and caregiver. The application includes a word-guessing game that fosters social support and collaboration between patient and caregiver.
“We hypothesize that in improving the relationship between patients and their caregivers, patients can function and manage their medications better,” said Harvard postdoctoral fellow Ziping Xu, who is leading the ADAPTS HCT algorithm development.
The app will employ reinforcement machine learning, in which the software will “learn” from previous interactions. For example, rather than simply sending preset reminders about medications, the algorithm will tailor timing and content according to when they have been most useful to patients. That way there is less chance the notifications will be deemed irrelevant or ill-timed and eventually habitually ignored.
“We use the algorithm to learn what is the best way to interact with each patient,” Xu said.
“We use the algorithm to learn what is the best way to interact with each patient.”
Ziping Xu
The Murphy lab is deploying its algorithmic expertise across other domains. With their University of Michigan collaborators, they’ve recently pilot-tested a program called MiWaves aimed at young adults who are abusing cannabis.
Like the ADAPTS HCT app, MiWaves continually learns and adapts from interactions with each patient to improve its decision rules, with the goal of helping them reduce their daily intake.
The lab is also several years into a project called Oralytics, which recently wrapped up a 10-week randomized trial to help refine the delivery of push notifications to help patients adhere to a tooth-brushing protocol: two sessions of two-minute duration daily, covering all four mouth quadrants.
The first Oralytics clinical trial included some 70 participants who all received the mobile app with a wireless-enabled toothbrush that sent data to the team’s collaborators at Proctor and Gamble.
Graduate student Anna Li Trella, who led the Oralytics project through the first trial, said the recently collected data will help the team develop methods to better handle messy problems like missing data and software errors.
“There are many constraints to running an algorithm in real life,” Trella said. “Now that we’ve conducted the first trial, we can make improvements to help the algorithm collect better data and learn better.”
Murphy thinks of her lab as creating practical pocket coacheswho can help people get where they want to go.
“Very, very few people can afford a human coach. And in fact, some people may not want such intensive human interaction,” Murphy said. “That’s where the idea for these digital supports comes in.”
Nation & World
When arguing cases before Supreme Court is your job
Elizabeth Prelogar (from left), Noel Francisco, and Neal Katyal offered an insider’s look at the job.Photos by Stephanie Mitchell/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
April 8, 2025
4 min read
Former solicitors general recall what it’s like representing U.S. government amid shifts on bench
When arguing cases before Supreme Court is your job
Elizabeth Prelogar (from left), Noel Francisco, and Neal Katyal offered an insider’s look at the job.
Photos by Stephanie Mitchell/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
4 min read
Former solicitors general recall what it’s like representing U.S. government amid shifts on bench
The late Supreme Court Justice Antonin Scalia made the bench “hot.”
Noel Francisco said lawyers used to be able to present arguments at their own pace before facing justices’ questions. But “Scalia changed that dynamic because he was the first one who was an active questioner.” Since then, other justices have taken up Scalia’s style, leaving lawyers less opportunity to shape the exchange.
Francisco should know, having worked on both sides of the bench. He clerked for Scalia from 1997 to 1998 and later served as U.S. solicitor general during the first Trump administration, arguing cases before the Supreme Court on the government’s behalf.
Last Friday, Francisco was joined by Elizabeth Prelogar, J.D. ’08, and Neal Katyal, who served as solicitors general during the Biden and Obama administrations, respectively. During a conversation with Richard Lazarus, the Charles Stebbins Fairchild Professor of Law, the three offered an insider’s look at the job and how it has changed since 2017 with the addition of four new justices.
Katyal credited Harvard Law School Professor Richard Lazarus’ counsel to get past his anxiety early in the job.
Changes to the court’s composition over the last two decades have affected the tone and the dynamic between the justices and advocates, and between the justices themselves, the trio noted.
There can be a “learning curve” for everyone, even the other justices, whenever a new justice gets seated, they noted. Sometimes, even a single justice, like the influential conservative Scalia or centrist Anthony Kennedy, often a “swing” vote, can have an impact on how lawyers argue cases.
Recalling one of his first appearances before the court, Katyal said Justice Sandra Day O’Connor “cared a lot about the facts of the case.” But after she stepped down, factual questions became “just one part” of the court dynamic at oral argument until Justice Sonia Sotomayor’s arrival in 2009.
The justices typically “didn’t have their minds made up as often as I feel like they do now,” Katyal said. Kennedy, in particular, “really didn’t know what he was going to do at the time of oral arguments in a lot of the big cases,” which gave the lawyers on both sides a greater opportunity to persuade the court.
Prelogar credits Justice Amy Coney Barrett, a former law school professor, with asking some of the toughest questions.
“She has this incredible ability to go multiple layers deep in unpacking an issue, always in a very fair way, a way that’s totally within bounds, and a way that’s very driven by a genuine desire to fully understand the ramifications of the government’s position in a particular case,” said Prelogar.
Kagan, the former HLS dean, is by far the toughest, say Francisco and Katyal, because she “dissects your case” and tests the very outer limits of one’s argument.
No question, they said, it can be terrifying, especially the first few cases before the court.
Francisco recalled referring to Justice Ruth Bader Ginsburg as Justice O’Connor, to gales of laughter from the gallery. They each sought advice from experienced colleagues or trusted law professors on how to manage their nerves and use their time at the podium wisely.
Katyal credited Lazarus’ counsel to get past his anxiety early in the job by viewing the back-and-forth with the justices at oral argument not as a battle to be won, but as a collaboration of ideas.
Win or lose, whatever you do, remember who the client is and don’t say something you later have to walk back.
“When you represent the United States and you’re standing at the podium in the Supreme Court, you’re committing the United States to a particular view of the law. You’re speaking this with the authority of the federal government, and you have to take some care, not ad hoc, making determination about what the positions of the United States will be,” Prelogar said.
Nation & World
Meacham sees a stark choice for America
Drew Faust (left) and historian Jon Meacham.Niles Singer/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
April 8, 2025
3 min read
Pulitzer-winning historian speaks to country’s past and future in conversation with Faust
The nation faces “a moral crisis” over whether we allow our best or worst impulses to preva
Pulitzer-winning historian speaks to country’s past and future in conversation with Faust
The nation faces “a moral crisis” over whether we allow our best or worst impulses to prevail in a battle for the soul of America, historian Jon Meacham told Harvard President Emerita Drew Faust during a conversation about history and U.S. democracy Wednesday at the Kennedy School.
Author of the 2018 book, “The Soul of America: The Battle for Our Better Angels,” Meacham said, “We either will decide that we can live in a country where we defer our immediate gratification in order to enter into a covenant where the rule of law prevails” — or we won’t.
Meacham believes an important political shift has taken place in recent years. In past presidential elections, like Richard Nixon’s narrow loss to John F. Kennedy in 1960, Americans could count on candidates to accept defeat regardless of how close or controversial the contest. That is no longer the case, he said.
“My central worry at the moment is that there’s an autocratic trend in the country that will be deepened and accelerated,” said Meacham, who teaches history at Vanderbilt University and won a Pulitzer Prize in 2009 for his book on Andrew Jackson, “American Lion.”
His fascination with presidents is not to build up Great Man-style mythology, but to reveal their inherent humanity, Meacham said.
“If history has any moral utility — and I think it does — I hope it is not to intimidate people with the grandeur and glory of someone’s life, but to show that flawed and broken people can do great things.”
Meacham served as an informal adviser and speechwriter to President Joseph R. Biden Jr. and was sometimes called Biden’s “muse” for their closely shared views of American democracy. When Faust, a Civil War historian, asked how he was able to go from writing about history to becoming part of that history, Meacham answered with a vivid memory.
“It was the moment I had been waiting for since I was 6 years old,” Meacham said. “It’s the Oval Office. The president of the United States is sitting behind the Resolute Desk, the sunlight streaming in. I can smell FDR’s cigarette smoke; I can see RFK reaching out to the Soviets. And I sit down next to the president’s desk, and the president of the United States asked me a question, and I start talking, and I didn’t make a goddamn bit of sense,” he said. “It was horrible.”
Meacham said that if he were president, he would not hold a serious meeting in the Oval Office because of how the past can overwhelm the present.
“I think it distorts things, and I think it’s really hard for presidents to get honest advice, particularly in that room,” he said.
Asked by a student how the legacy of slavery informs the current political climate, Meacham answered: “I think that we have not dealt with it, and we live in the extraordinarily long shadow not just of Appomattox, but of Reconstruction.”
Referencing Edward Alfred Pollard, the Richmond newspaper editor who coined the term “The Lost Cause” in his 1866 history of the war, Meacham noted, “He says explicitly that ‘Though we have lost the war, we have not lost the fight for the principle, which was the principle of white supremacy.’ And I think we live with that tension now.”
Conversations with palliative care specialist Susan Block (second from left) were instrumental to the development of “Night Side Songs” by Daniel Lazour and Patrick Lazour (far left and far right), seen here with Amanda Moment, a social worker from Dana-Farber and BWH. Courtesy of Susan Block
Arts & Culture
‘Singin’ in the Rain’ this isn’t
But palliative care specialist who advised on ‘Night Side Songs’ says new musical about cancer patient is rich, moving
Conversations with palliative care specialist Susan Block (second from left) were instrumental to the development of “Night Side Songs” by Daniel Lazour and Patrick Lazour (far left and far right), seen here with Amanda Moment, a social worker from Dana-Farber and BWH.
But palliative care specialist who advised on ‘Night Side Songs’ says new musical about cancer patient is rich, moving
Anna Lamb
Harvard Staff Writer
5 min read
Susan Block, founding chair of the department of psychosocial oncology and palliative care at Dana-Farber Cancer Institute and Brigham and Women’s Hospital, has been seeing dying patients for more than three decades. She had trouble imagining how Daniel and Patrick Lazour, who approached her for advice, were going to be able to build a musical around her sobering area of specialty.
“I had some skepticism about the idea of a musical about death and dying,” said Block, who is also founding director of the Harvard Medical School Center for Palliative Care. “And I mean, I love any kind of theatrical performance. And I like musicals. But I just couldn’t quite juxtapose this.”
But, she said, her doubts dissipated after seeing the first run-through of “Night Side Songs.”
“There was a feeling by the end, that we had all been through something together,” Block said.
“When I was a medical student and an intern, I didn’t like the way people who were dying were treated in the hospital. I thought that they were infantilized …”
Susan Block
“Night Side Songs,” inspired by writer and cultural critic Susan Sontag’s observation that “illness is the night side of life,” is told through the voices of doctors, patients, researchers, and caregivers. It was commissioned by Harvard’s American Repertory Theater and is being staged at the Cambridge Masonic Temple through Sunday and Hibernian Hall in Roxbury April 9-20.
The story revolves around Yasmine, a young cancer patient played by Brooke Ishibashi. The Lazour brothers conducted years of research into end-of-life care and experiences, and they asked Block to review drafts and attend read-throughs to give notes on accuracy.
“I felt that they captured essential elements of the experience from the point of view of patients, of caregivers, of other family members going through it, and of the clinicians in a really very emotionally evocative, intense, beautiful way,” said Block, who has seen the show multiple times since its inception.
Block went to medical school in the late 1970s and early 1980s. She said back then there was no such thing as palliative care. She has been a pioneer in studying the psychology of dying and getting palliative care into hospitals across the country. Now, a musical is inviting people to think and speak candidly about the end of life.
“When I was a medical student and an intern, I didn’t like the way people who were dying were treated in the hospital,” she said. “I thought that they were infantilized in ways — that was a period where people weren’t told the truth about their illness, where pain was not well treated, where there was not good recognition of people’s emotional suffering about and grief about the idea of leaving, that families were kind of left to figure it out on their own.”
Since then, palliative care has become a recognized area of specialization involving thousands of doctors across the country. Still, Block said, we don’t talk enough about death and dying.
“I think giving people the opportunity to speak about this lets people play around with it, because most of us do a lot of our deeper understanding and processing by talking with somebody else in community,” she said. “And for people who are seriously ill and dying, there’s this feeling that if I tell my wife how upset I am about my illness, it’s going to make her sad and make things worse for her. And then the wife is saying, ‘Well, I want to protect my husband from knowing how sad I am.’ There’s this conspiracy of silence about it, and it also creates enormous isolation for both people.”
Jonathan Raviv in A.R.T.’s world premiere production of “Night Side Songs.”
Credit: Nile Scott Studios
Notably, “Night Side Songs” is not being performed at the A.R.T.’s Loeb Theater, which accommodates audiences more than twice the size of either Masonic Temple or Hibernian Hall. Both venues also allow for theater in the round, with audience members seated in a circle around the performers.
According to A.R.T. Artistic Director Diane Paulus, the show is being performed in these more intimate venues to inspire audiences to connect with both the actors and each other.
“Getting out of the proscenium arch, the strict auditorium, breaking that into a circle, reducing the audience to make it intimate, and audience size really matters,” she said. “And our mission is to expand the boundaries of theater. So we are always looking for shows like ‘Night Side Songs’ that are pushing the boundaries of what we think the form of theater is.”
The other unifying element, Paulus said, is the invitation for the audience to sing along.
“The way they do it is so inviting and graceful. And you can sing along, and you can listen … It’s really an invitation for the audience to experience the material in a very deep way,” she said.
Block says “Night Side Songs” will resonate with anyone who’s been touched by serious illness.
“When you’re sick, you want to believe that science and medicine know what to do, and everything is going to work out OK,” she said. “But then unexpected things happen, and I thought that the play dealt with the uncertainty and expectation of unexpected outcomes in a very real, very poignant way.”
Health
How to manage stress during an apocalypse
Psychology professor Athena Aktipis (right) brought a lighter note to her lecture, “A Field Guide to the Apocalypse,” when she was joined by guitarist Forest Thurman. Audience members raise their hands in response to a survey about bluegrass music. Photos by Niles Singer/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
April 7, 2025
5 min read
Psychology professor Athena Aktipis (right) brought a lighter note to her lecture, “A Field Guide to the Apocalypse,” when she was joined by guitarist Forest Thurman. Audience members raise their hands in response to a survey about bluegrass music.
Photos by Niles Singer/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
5 min read
Psychologist says scrutinizing risk factors, embracing community, adventure are key in age of angst over climate, AI, pandemics
Cooperation, community, and a sense of adventure may be the keys to our survival, even in these violently divided times.
We seem to be living in an extraordinarily tumultuous moment of global outbreaks of deadly viruses, a dangerously warming planet, and coming economic and social displacement of technologies, including AI. But, Akiptis said, crises are nothing new to the human race. In fact, we are constantly managing risk. The dilemma is that often the solution isn’t clear-cut.
Akiptis presented the hypothetical case of the “goosile.” A suspicious blob appears on the radar of a mission control professional assessing attack threats. It could be a missile, which should be shot down. Or it could be a harmless goose (hence the mash-up neologism). What do you do?
“The problem is that the world is filled with ambiguity,” explained Aktipis. “Either you correctly identify more missiles but have more goose false alarms, or you correctly reject more geese, but miss some missiles.”
“The bottom line in managing our stress in these apocalyptic times … is gathering information so you can figure out what you actually do and don’t need to be stressed about,” said Aktipis.
In other words, there may be no “right” answer, and that means more stress.
“The bottom line in managing our stress in these apocalyptic times … is gathering information so you can figure out what you actually do and don’t need to be stressed about,” said Aktipis, co-director of the Human Generosity Project and the Cooperation Science Network.
Taking principles from psychology and evolutionary biology, Aktipis has created an accessible and actionable framework. The first step is to look “at a potential threat from multiple perspectives.” Then, “attend to all of your senses when assessing a threat.” Third, reach outside yourself: “Find as many dimensions of information as you can.” That leads to her next suggested action: “Talk to people who have different knowledge than you do.” And finally, “Know when to stop gathering information.” You may need to move on — or take action. “Don’t get stuck in a risk-assessment loop,” she said.
Instead, she stressed, we must learn to live with risk.
“Thanks to the recent pandemic, many of us are likely accustomed to being miserable a considerable amount of time, even when we’re not facing the red-hot heat of an active apocalypse,” said Aktipis. “We put up with having a life that is often painful, boring, or some combination of the two.”
Changing this mindset can actually make us better prepared, letting us build up “apocalyptic sustenance.”
It may help to change priorities.
“I’m not saying that we shouldn’t work hard, just that we should work hard on things that we’re actively deciding to do because they are important. And ideally also what would be kind of fun,” she continued. “We should reawaken that childlike part of us that is curious and likes amusement and then work hard on something that feeds that inner child with something delightfully playful.”
“A Field Guide to the Apocalypse” contains multiple outlines and suggestions for how to make this possible. One example is CHESS, an acronym for incorporating “Curiosity, Humor, Entertaining, Storytelling, and Socializing” into our lives.
Emphasizing the last S, Aktipis said: “The connections that we’ve forged through these social events can form the basis of mutual aid relationships that can come in handy during real catastrophes.”
Apocalypses come in many forms. Drawing on the original Greek definition, an apocalypse was “revelation of the underlying risk in the world and in our lives,” she said: “Rather than thinking of it as the end of the world, it’s an opportunity for us to learn and understand what the world really is like, and that can help us be better prepared and adapt as things are changing.”
Another key is not seeing survival or success as a zero-sum game. That thinking leads to the belief that “we all have to fight over the pie.” Instead, she suggested, “We can work together to make a bigger pie and share it.”
Utilizing game and cooperation theories, she laid out the work of the transdisciplinary Human Generosity Project, beginning with the Maasai people in Kenya, who have a traditional system called Osotua.
Literally translating to “invisible umbilical cord” (according to the Osotua Foundation),this social system assumes members of a group will give when asked, as long as long as they can help “without going below what they themselves need,” with no expectation of return, Aktipis explained.
“The only expectation is that they would be recipients of the same kind of help if they needed it in the future.”
This, she said, is similar to many of our own friendship and family bonds. Indeed, research in Fiji, Mongolia, and ranchers in the Southwest confirmed the universality of such “social insurance” bonds.
“Across all of these societies, people are managing risk through their social interactions, often through these need-based transfers.
“There is a lot of potential to change the way we handle risk collectively,” said Aktipis.
To drive home her points — and, perhaps, to build a little community among the crowd in Science Center A — she invited bluegrass guitarist Forest Thurman to join her as she brought out her ukelele to lead the audience in simple, tuneful singalongs with lines like “Life ain’t a prison/it’s a pie.”
Sonia Vallabh and Eric Minikel.Photos by Veasey Conway/Harvard Staff Photographer
Health
Team hits milestone toward prion disease treatment. For them, it’s personal.
Alvin Powell
Harvard Staff Writer
April 7, 2025
5 min read
Patient-scientist, husband among researchers who developed promising gene-editing therapy for rare, fatal condition
New research provides hope that prion disease — a
Team hits milestone toward prion disease treatment. For them, it’s personal.
Alvin Powell
Harvard Staff Writer
5 min read
Patient-scientist, husband among researchers who developed promising gene-editing therapy for rare, fatal condition
New research provides hope that prion disease — a handful of rare, invariably fatal disorders caused by misfolded proteins in the brain — may, in the not-too-distant future, have a treatment if not a cure.
The work, published early this year in the journal Nature Medicine, showed that altering a single base in the gene that produces the killer proteins can reduce by half the amount of that protein in the brains of laboratory mice, a step that extended their lifespans 52 percent.
Authors of the work, at the Broad Institute of MIT and Harvard, caution that several potentially lengthy steps remain before human trials of the technique can be undertaken. Still, they agreed that the results indicate the pathway that they embarked upon nine years ago toward effective treatment in humans appears promising.
“I think it’s a milestone for sure,” said David Liu, senior author of the paper, in whose lab the base editing technology was developed. “One has to be careful to recognize that the path to an actual clinical trial has many such milestones that have to be traversed.”
Prion disease includes several conditions that lead to brain damage and dementia, including Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Scheinker disease, and fatal familial insomnia. About 15 percent of cases are due to an inherited mutation in the prion protein gene, while 85 percent are “sporadic,” occurring when these proteins spontaneously fold into abnormal, toxic shapes.
‘Personal’ mission for scientist who is also a patient
While laboratory work is often remote from the patients it is intended to help, these experiments are part of a personal mission for several of the papers’ authors. That’s because one of them, HMS Assistant Professor of Neurology Sonia Vallabh, has tested positive for an inherited form of prion disease called fatal familial insomnia.
In late 2010, Vallabh’s mother died of a mysterious, degenerative condition that subsequent tests would confirm as fatal familial insomnia. Not long after, Vallabh herself tested positive for the disease-causing mutation. That prompted Vallabh, who had graduated from Harvard Law School, and her husband, Eric Minikel, who holds a planning degree from MIT, to retrain for careers centered on understanding and developing a treatment for prion disease. Today, the pair run their own lab at the Broad, employing 14 researchers. In a relatively short time, Liu said, they have become experts on the therapeutically relevant aspects of the condition.
“It’s an incredible privilege to be able to work with them,” said Liu, the Thomas Dudley Cabot Professor of the Natural Sciences in Harvard’s Faculty of Arts and Sciences and a core institute member at the Broad. “Their personal connection to the disease provides extraordinary motivation for everybody to try to make as much progress as we can — carefully, but as efficiently as possible.”
David Liu.
The encouraging results build on discoveries in Liu’s lab, which pioneered the single base editing technique used in the experiments. That technique has been used in 13 clinical trials, Liu said, and has benefited patients suffering from hypercholesterolemia, sickle cell disease, T-cell leukemia, and beta thalassemia.
“David took us seriously long before anyone had much reason to, so we’ve had a collaboration with him for a good while,” said Minikel, who is also assistant professor of neurology at Harvard Medical School. “It’s been a perfect collaboration in the sense that Sonia and I have always felt like we care a lot about this disease, but we’re not technology development people. We’ll say, ‘Here’s the models and assays and the tools needed to develop a drug for this disease,’ but we’re probably not the ones who are going to make the drug.”
In the current work, researchers used a mouse model of human prion disease, which increases the chance the work will successfully translate to humans. The research — funded by the National Institutes of Health, the Broad, the Prion Alliance, and the Howard Hughes Medical Institute — involved inserting a genetic base editor developed in Liu’s lab into adeno-associated virus, which acts as a vector that homes in on cells and inserts its DNA cargo into their genomes. That rewrites the cellular instructions for producing the protein, in this case halting production.
“Having a friend, a collaborator, who could benefit from this treatment really does a lot on the personal motivation side.”
Meirui An
Meirui An, a graduate student in Liu’s lab and one of the paper’s first authors, said that sometimes the vector itself can cause illness, so to improve safety researchers tweaked that part of the process, ultimately seeing a 63 percent reduction in prion protein production despite using a significantly lower dose of the vector virus.
The prion’s dangerous, infectious nature may make this research among the last conducted with human prion protein, Liu said. Such research was restricted after an accidental exposure in a French lab led to a researchers’ death from prion disease.
Human trials of any therapy that might emerge from the work remain several years away, Liu said. Whatever the needed intervening steps turn out to be, researchers said they will likely include refinement of the base editor — which is so large that it has to be transported into cells in two separate viral capsules — improved targeting to reduce its integration into the cells of other tissue types, and improved efficiency in reducing production of prion protein.
An and others praised the collaborative process between the labs involved, which included that of the Broad’s Benjamin Deverman, who specializes in vector engineering.
“Our exchanges have been really frequent and to me, personally, it’s extremely inspiring to work with patient-scientists,” An said. “I don’t need to find any external source of motivation to work on this project because just having a friend, a collaborator, who could benefit from this treatment really does a lot on the personal motivation side.”
Jeannie T. Lee.Courtesy of Harvard Medical School
Science & Tech
Decades later, a chromosomal breakthrough
Jell-O-like substance could be key to treating Fragile X and Rett syndromes
Saima Sidik
Harvard Correspondent
April 7, 2025
4 min read
The X chromosome creates a challenge for human cells. Unlike most chromosomes, which are present in duplicate regardless of a person’s sex, femal
Jell-O-like substance could be key to treating Fragile X and Rett syndromes
Saima Sidik
Harvard Correspondent
4 min read
The X chromosome creates a challenge for human cells. Unlike most chromosomes, which are present in duplicate regardless of a person’s sex, females have two copies of X while males have only one. Females don’t need twice as many of the genes encoded on the X chromosome as males, however, so they must inactivate one of their two copies.
How this inactivation occurs has been a long-standing question in cell biology — one Jeannie Lee’s lab at Mass General has been central to answering. In a study published last month, Lee and her colleagues describe how cells orchestrate this chromosomal silencing. The findings could lead to relief for the many thousands of people living with diseases caused by mutations on the X chromosome.
Inactivation depends on a gelatinous substance that coats all chromosomes, creating discrete bubbles that work as separators. “It’s like Jell-O. And if chromosomes weren’t surrounded by this Jell-O, they’d get tangled up like spaghetti,” says Lee, who is vice chair of the Department of Genetics at Harvard Medical School.
At the X chromosome, things get a bit more complicated. A gene on this chromosome instructs cells to make an RNA molecule called Xist (pronounced “exist”) that changes the material properties of the “Jell-O” around the X chromosome. When Xist first comes into contact with the Jell-O, the two engage in a tug-of-war, each pulling on the other. But Xist is no match for the Jell-O, and so it gets engulfed. Once inside, Xist changes the biophysical properties of the Jell-O, making it more flexible and closer to a liquid.
Other molecules important for X-chromosome inactivation also infiltrate the Jell-O. Together with Xist, these molecules work their way into nooks and crannies along the chromosome that would not be so accessible if the Jell-O were stiffer and thicker. By coating the X chromosome, they render it inactive. “It’s that simple!” Lee says.
But as simple as it sounds, figuring out how X-inactivation works has taken decades. At the end of this long journey lies a tantalizing possibility: Freeing inactivated X chromosomes could cure certain genetic disorders. That’s because mutations are often present on only one of two X chromosomes, but the healthy version of the gene is bound up in the inactivated chromosome, making it unavailable for cells to use.
The Lee lab has developed a number of approaches to unsilence X-linked genes in isolated cells, making them potential treatments for two such diseases: the intellectual disability Fragile X Syndrome and the neurodevelopmental disorder Rett Syndrome. “We’ll be further optimizing the approaches and doing safety studies over the next couple of years, and then we hope to move these compounds into clinical trials,” Lee says.
These treatments could also benefit males, even though their cells don’t use X-inactivation. A similar process silences individual genes on the X chromosome if they carry certain mutations, such as a mutation that causes Fragile X Syndrome.
Mysteries remain, however. For example, freeing inactivated X chromosomes seems to restore the function of mutated genes without having much impact on healthy genes carried by the chromosome. That’s encouraging because it suggests that this strategy can cure diseases with minimal side effects, but it’s not clear why other X chromosome genes remain largely unaffected. Lee thinks cells may have a limited capacity to use each gene, and that capacity is already maxed out by a single copy of a healthy gene. With mutated genes, on the other hand, the cell still has the capacity to use the healthy version when it becomes available.
Today, the clinical potential of Lee’s work is obvious, but that hasn’t always been the case. “We were supported by the National Institutes of Health for 25 years to answer a really basic question: How is the X-chromosome inactivated? And it’s only recently that we had this ‘Aha’ moment and realized we could get to a therapeutic,” she says.
The research described in this story received funding from the National Institutes of Health.
Campus & Community
Richard P. Lifton to join Harvard Corporation
Scientist to start with governing board on July 1, succeeding Shirley Tilghman
April 7, 2025
5 min read
Richard P. Lifton, a prominent leader in biomedical research and higher education, will join the Harvard Corporation this summer, the University announced Monday. A scientist and physician who is a pioneer in using genetics and genom
Scientist to start with governing board on July 1, succeeding Shirley Tilghman
5 min read
Richard P. Lifton, a prominent leader in biomedical research and higher education, will join the Harvard Corporation this summer, the University announced Monday. A scientist and physician who is a pioneer in using genetics and genomics in understanding human disease, Lifton has served as the 11th president of The Rockefeller University since 2016 and also leads that institution’s Laboratory of Human Genetics and Genomics.
“Rick is known to colleagues as a person of deep integrity, extraordinary intellectual curiosity and creativity, exceptional incisiveness, and sound judgment,” said President Alan M. Garber and Senior Fellow Penny Pritzker in a message to the Harvard community. “He has dedicated his life’s work to the advancement of higher education and the progress and promise of science, embracing and embodying the pursuit of academic excellence. We look forward to welcoming Rick Lifton to the Corporation this summer, as we navigate these consequential and challenging times for our own university and others.”
“Harvard is a national treasure for its leadership in education, scholarship, and research. Its generation of new knowledge advances the betterment of humanity with global impact.”
Richard P. Lifton
Under Lifton’s leadership, Rockefeller has strengthened its position as one of the world’s preeminent research institutions, including by fostering support for new programs in basic, translational, and clinical research, constructing a new campus in Manhattan, and collaborating in the creation of Chan Zuckerberg Biohub New York. Lifton is also a champion for Rockefeller’s multidisciplinary faculty, whose members have received two Nobel Prizes, three Lasker Awards, and two Breakthrough Prizes in life sciences during his tenure.
“Harvard is a national treasure for its leadership in education, scholarship, and research. Its generation of new knowledge advances the betterment of humanity with global impact,” Lifton said. “I’m honored to join President Garber and the other distinguished members of the Corporation, and I look forward to working with them and other colleagues to ensure that Harvard sustains and enhances its exceptional contributions to society.”
Lifton’s pathbreaking research has centered around genetic material that underlies common problems in human health, including cardiovascular disease, neoplasia, kidney disease, and osteoporosis. He is especially known for his discovery of mutations in 20 genes that drive blood pressure to high or low extremes by altering renal salt reabsorption, work that has informed public health efforts and therapeutic strategies worldwide.
Lifton joined the faculty of Yale University in 1993. Over nearly a quarter-century, he served as chair of the Department of Genetics at Yale Medical School, a Howard Hughes Medical Institution Investigator, and as director of two research centers. He rose to become a Sterling Professor, Yale’s highest academic rank, and was a member of Yale’s presidential search committee.
Before being recruited to Yale, Lifton served on the faculty of Harvard Medical School from 1986 to 1993. He did his medical residency at Brigham and Women’s Hospital, where he became chief medical resident. A summa cum laude graduate of Dartmouth College, he earned an M.D. and a Ph.D. in biochemistry from Stanford University.
Across his career, Lifton has served on many boards, committees, and councils related to scientific discovery and science policy, including scientific advisory boards for the Broad Institute of MIT and Harvard and Massachusetts General Hospital. His many roles have included chairing the White House’s Precision Medicine Initiative, co-chairing the International Commission on the Clinical Use of Human Germline Genome Editing, and serving as a member of both the governing council of the National Academies and the advisory committee for the director of the National Institutes of Health. He has served on fiduciary boards and scientific advisory boards for various biotechnology and pharmaceutical companies, and he was a member of the presidential search committee for the Institute of Medicine (now the National Academy of Medicine).
“Richard Lifton is a thoughtful and highly respected leader with a profound commitment to advancing education, science, and human health,” said Vivian Hunt, president of the Board of Overseers. “His expertise in guiding a renowned research university and his extensive engagement as an admired leader and sought-after adviser within the broader biomedical field will strengthen Harvard’s governing boards. I know my colleagues are excited to work with him.”
In line with Harvard’s charter, Lifton was elected by the Corporation with the consent of the Board of Overseers. He will become a fellow of Harvard College on July 1, filling the vacancy created by the planned departure of Shirley Tilghman, an eminent life scientist and president emerita of Princeton University.
Garber and Pritzker thanked Tilghman for “having brought to the Corporation an extraordinary combination of university leadership experience, academic stature and scientific accomplishment, engagement with a wide array of other institutions, and constant devotion to higher education’s highest ideals.” They expressed their profound gratitude to Tilghman for “continuing exemplary service” that “sets a standard for us all.”
Known formally as the President and Fellows of Harvard College, the Harvard Corporation is the oldest corporation in the Western Hemisphere. Chartered in 1650, the Corporation exercises fiduciary responsibility with regard to the University’s academic, financial, and physical resources and overall well-being. With 13 members, the Corporation is one of Harvard’s two governing boards. Members of Harvard’s other governing board, the Board of Overseers, are elected by holders of Harvard degrees.
Science & Tech
Lower canopies show struggle for tropical forests
Clea Simon
Harvard Correspondent
April 7, 2025
4 min read
NASA technology guides scientists as they track health of ‘Earth’s lungs’
With their ability to store carbon, forests are often considered the lungs of the Earth, but they are vulnerable to the world’s ills, too. A new study, using NASA laser technology from the
NASA technology guides scientists as they track health of ‘Earth’s lungs’
With their ability to store carbon, forests are often considered the lungs of the Earth, but they are vulnerable to the world’s ills, too. A new study, using NASA laser technology from the International Space Station, reveals the impact of climate change on global tropical forests with greater depth and breadth than ever before.
The forest canopy, the upper layer of mature trees, “is a very critical indicator of forest health and ecosystem productivity,” explained Shaoqing Liu, a postdoctoral fellow in Organismic and Evolutionary Biology (OEB) and the first author on the paper.
Shaoqing Liu.
Courtesy photo
“In general, taller canopies are associated with high carbon storage and greater above-ground biomass. Tall canopies can buffer the microclimate,” Liu said, even helping reduce the temperature during heat waves. The study looked at tropical forests in Asia, Africa, and South America — lands with minimal disturbances or human activities such as logging.
To measure changes in such forests, his group used laser measurements from GEDI, which allowed the group to study a wide swath of forests globally, whereas earlier studies had been limited to small areas.
“Over the past decade, NASA has been using the International Space Station as a convenient platform for evaluating new forms of space-based remote sensing measurements,” said Paul Moorcroft, professor of OEB and senior author of the study. “The Global Ecosystem Dynamics Investigation waveform LiDAR is a prime example of this approach.”
GEDI — pronounced “Jedi” — “can tell us the vertical structure of the forest canopy” such as leaf density, said Liu. “Our study demonstrates that climate, topography, and soil properties account for almost three-quarters of the variation in tropical forest canopy height. We also found the elevation, dry season, and solar radiation are the most important variants to determine the canopy height.”
The researchers discovered that “tropical forests in the southern Amazon area are vulnerable to climate change” because of increasingly prolonged dry seasons. “The dry season is the dominant driver determining forest canopy height in this area,” said Liu.
Because global climate model projections show that this area will have longer dry seasons, “We may see significant reductions in canopy height,” he added.
“Understanding the environmental controls of tropical forest height is important for assessing the carbon sequestration and conservation value of different tropical forest areas,” said Moorcroft. “Understanding the environmental drivers of forest canopy height variation is also crucial for understanding how tropical forests will respond to climate change.”
The impact of climate change is not uniform, however. Thanks to GEDI, the researchers were able to view differences in its manifestation and effect on the canopy. “In the central Amazon, because it is relatively moist, the first important driver is actually elevation,” said Liu. This was also true in Africa, the researchers found.
Looking ahead, Liu would like to move beyond studying the primary forest to examine more of the globe’s forest and woodland areas. He said he hopes these studies will influence policy.
“In terms of climate-change policies, we see the tropical forests are not only biodiversity hotspots, they are critical for carbon storage. Protecting them is essential for mitigating climate change,” he said. “We hope to help policymakers help identify areas that are vulnerable to climate change and prioritize them.”
Funding for this study was provided, in part, by a NASA grant.
Alberto Ascherio, Joel Habener, and David Liu.Photos courtesy of Alberto Ascherio and Joel Habener, photo by Veasey Conway/Harvard Staff Photographer
Health
Harvard researchers awarded Breakthrough Prizes
‘Oscars of Science’ recognize advances in gene editing and physics and against MS, obesity
April 6, 2025
5 min read
Three Harvard researchers received 2025 Breakthrough Prizes — the “Oscars of Science”
‘Oscars of Science’ recognize advances in gene editing and physics and against MS, obesity
5 min read
Three Harvard researchers received 2025 Breakthrough Prizes — the “Oscars of Science” — on Saturday. Also recognized was the ATLAS general-purpose particle physics experiment at CERN, to which Harvard faculty, researchers, and students have made significant contributions.
The Breakthrough Prize, founded in 2013 by Sergey Brin, Priscilla Chan and Mark Zuckerberg, Yuri and Julia Milner, and Anne Wojcicki, honors achievements in life sciences, fundamental physics, and mathematics.
Six prizes were announced. The Harvard recipients are:
Alberto Ascherio, a professor of epidemiology and nutrition at the Harvard T.H. Chan School of Public Health and a professor of medicine at Harvard Medical School, was recognized for work establishing Epstein-Barr virus infection as leading cause of multiple sclerosis.
MS is a chronic inflammatory disease of the central nervous system that affects about 2.9 million people worldwide and currently has no cure. Epstein-Barr is a herpes virus that can cause mononucleosis and establishes a lifelong latent infection.
Although there was no single eureka moment in Ascherio’s more than 25-year effort to identify the cause of multiple sclerosis, the results of his 2022 Science study were undoubtedly dramatic. Using data from more than 10 million U.S. soldiers monitored over a 20-year period, Ascherio and his colleagues found that infection with the Epstein-Barr virus significantly increased the risk of developing multiple sclerosis later in life — the first compelling evidence of a cause for this devastating disease.
The discovery revolutionized the field of MS research, and a vaccine and antibody drugs that target Epstein-Barr are now in development. “It’s virtually a consensus now that Epstein-Barr is the leading cause of MS,” Ascherio said. “I’m happy to say that finally, after 25 years, it’s been a big splash.”
Read more about Ascherio and the MS/Epstein-Barr research here.
Joel Habener, a professor at Harvard Medical School, was part of a group of scientists honored for contributions to the discovery and characterization of the hormone glucagon-like peptide-1, or GLP-1 — findings that subsequently led to the development of treatments based on GLP-1.
GLP-1 is a hormone produced by the small intestine that plays a key role in regulating blood sugar, controlling appetite, and modulating digestion. To coordinate these complicated tasks, the hormone must simultaneously communicate with other hormones and with multiple organs and systems, including the stomach, pancreas, liver, brain, heart, blood vessels, and immune system.
The body of research conducted by the five scientists, supported in part by federal funding, has dramatically advanced understanding of how GLP-1 functions in the body. Notably, their work contributed to the development of GLP-1 drugs, which have revolutionized treatment for Type 2 diabetes and obesity.
Read more about Habener and the GLP-1 research here.
David Liu — the Richard Merkin Professor at the Broad Institute, director of the institute’s Merkin Institute for Transformative Technologies in Healthcare, and the Thomas Dudley Cabot Professor of the Natural Sciences at Harvard — was honored for the development of the gene editing platforms base editing and prime editing, which can correct the vast majority of known disease-causing genetic variations and have already been used in at least 15 clinical trials, with life-saving results. Base editing was recently used to achieve the first-ever correction of a disease-causing mutation in patients.
Base editing, which Liu’s team developed in 2016, is a gene editing technique that directly converts an individual DNA base pair into a different base pair. Prime editing, which Liu’s group pioneered three years later, can make insertions, deletions, and substitutions up to hundreds of base pairs long in the genome.
Since their initial development, both base editing and prime editing have been used by thousands of laboratories around the world and have enabled the study and potential treatment of many genetic diseases.
“The real heroes behind our work are the incredibly talented graduate students, postdocs, and collaborators who worked tirelessly to develop these technologies in ways that would allow them to benefit society,” said Liu. “Without their dedication, this work would not be possible. The honor of my professional life is to be able to work with and support such a vibrant group of scientists.”
Read more about Liu and the gene editing research here.
Three Harvard faculty in the Physics Department as well as several students and researchers were recognized with the Breakthrough Prize in Fundamental Physics for their work on the ATLAS collaboration. The team of 13,000 physicists, engineers, and technicians conducts general-purpose particle physics experiments at the Large Hadron Collider at CERN. Harvard members of ATLAS include Melissa Franklin, Mallinkrodt Professor of Physics; Masahiro Morii, Donner Professor of Science; John Huth, Donner Professor of Science; postdocs Rongkun Wang, Aaron White, Knut Koch, and Simone Francescato; and Harvard Griffin GSAS students Gustavo Kehris, Laura Bruce, Kees Bekendorfer, Jerry Ling, and Alexis Mulski.
Arts & Culture
‘Everybody feels like two people’
Apple TV+ Press
Sy Boles
Harvard Staff Writer
April 4, 2025
6 min read
Alum who co-produces ‘Severance’ says show speaks to real-life mysteries
The Apple TV+ show “Severance” wrapped up its second season last month, leaving fans with a lingering sense of unease about what just happened and what comes next.
“Severance” follows a grou
Alum who co-produces ‘Severance’ says show speaks to real-life mysteries
The Apple TV+ show “Severance” wrapped up its second season last month, leaving fans with a lingering sense of unease about what just happened and what comes next.
“Severance” follows a group of office workers who have chosen to undergo a procedure that separates their consciousnesses into an “innie” who only exists at the office and an “outie” who exists everywhere else, each with no memory of the other’s experiences. It’s about work-life balance, but it’s also about free will, identity, and the feeling of being at war with oneself.
Among the show’s producers is Nicky Weinstock, who graduated from Harvard College in 1991. In this edited conversation with the Gazette, he talks about “Severance” as a “willfully strange” provocation and a TV sensation, and recalls his transition from Cambridge to Hollywood.
What do you most remember about your time on campus?
At Harvard, I found a lot of friends and professors and inspirations from all over the planet. It was very energizing as a place.
Ironically, I spent a lot of time leaving it, because I was an anthropology major and did anthropology work in Kenya and went to the University of Nairobi for a while, and spent as much time as I could traveling. All of it was very much of a piece, I think, in terms of being free-range and talking about writing and creativity with all kinds of people in all kinds of places.
To be honest, when I got to Hollywood and started producing, I was shocked that Hollywood did not seem to have much interest in other places. I sucked it up and was able to do a lot of fun, Hollywood-based projects, but I always wanted to have a global sensibility. Finally, about three years ago, I was able to start my own company and draw stories from all over the world.
Nicky Weinstock.
Photo courtesy of Nicky Weinstock
How did you get involved with “Severance” and what did you first think of the concept?
“Severance” found me in a very lucky way. It was a script by Dan Erickson. Dan had never produced a television series before, and in fact he didn’t have an agent. The script started to be passed around and noticed and was generating excitement. I was running a company called Red Hour with Ben Stiller. I had never seen a concept like that. It’s what everyone hopes for in movies and television: something that A) hasn’t been done before and B) is perfectly rendered. This had both, all credit to Dan.
We began to develop it together and refine the pilot script. We managed to sell it to Apple and proceeded to package it with actors and with Ben directing it, and to make a reality of it in a way that doesn’t usually happen in Hollywood. Most of the time you start with a known writer; you start with massive actors. In this case it was literally the coolness of the idea that attracted everybody: John Turturro, Christopher Walken, Patricia Arquette. They all responded to the sheer originality and resonance of the idea.
Are you surprised that the show has taken on a life of its own?
Yes and no. It surprised me because it was always willfully strange. It was always committed to the specificity of that world. That can often lead to a very fringe-y phenomenon that doesn’t catch on with a wide audience.
But then again, I was not that surprised, because what I responded to when I first read it is what people respond to, which is that everybody feels like two people in their lives, at least. Everybody has a certain persona at their job and a different persona at home, and everyone is trying to reconcile different aspects of their lives into some coherent whole, and we spend all our lives doing it.
“Everybody has a certain persona at their job and a different persona at home, and everyone is trying to reconcile different aspects of their lives into some coherent whole, and we spend all our lives doing it.”
The trajectory of the show seems to mirror our experience during and after COVID. Season 1 came out in 2022, and it felt like a very closed world, and then Season 2 expands that world to ask bigger questions about what it means to be a person.
I very much agree. Season 1 was very much a result of how we were living at the time, and that claustrophobia and confusion and isolation was very much part of our culture. I think that’s why a lot of people responded to it the way they did. And the world has only gotten stranger since then. The unpredictability and the shakiness and the bottomlessness that we’re all going through right now is why people responded to the show, too.
For everyone, across the political spectrum, no matter where you live, there is a sense of “Where is the world going right now?” and “What do the people in power know and what is their intention?” That was not true when I was growing up. “Severance” has become a little bit of a vessel to demonstrate that mysteries abound and we don’t know who to trust.
The second season ended on a bit of cliff-hanger that I won’t spoil, but was essentially about an “innie” character making a dramatic choice that heightened the stakes and set up a lot of new questions for the third season. Is there anything you can say about where the show will go?
I can’t say much, but I can say that the concept of severance is so expansive. We wanted to do a first season that was claustrophobic. We wanted to do a second season that was out in the world. The idea of bifurcating your life and having different selves can go in so many directions. All I can say is Season 3 will not look anything like Season 2 or Season 1. It’s an expansive idea.
Nation & World
Former Greek PM outlines strategies to strengthen EU
Encourages European autonomy while retaining trans-Atlantic dialogue
Clea Simon
Harvard Correspondent
April 4, 2025
5 min read
Alexis Tsipras.Photo by David Elmes
Stressing the need for European reform and unity in the face of multiple challenges, Alexis Tsipras, the former prime minister of Greece, addressed a standi
Former Greek PM outlines strategies to strengthen EU
Encourages European autonomy while retaining trans-Atlantic dialogue
Clea Simon
Harvard Correspondent
5 min read
Alexis Tsipras.
Photo by David Elmes
Stressing the need for European reform and unity in the face of multiple challenges, Alexis Tsipras, the former prime minister of Greece, addressed a standing-room-only crowd at the Minda de Gunzburg Center for European Studies on March 25, which marked Independence Day in Greece.
Tsipras presented proposals for Europe to counter looming financial and trans-Atlantic turbulence, strengthen its cohesion, and elevate its geopolitical and economic position. The presentation was moderated by Peter A. Hall, Harvard’s Krupp Foundation Professor of European Studies and a resident faculty member at CES, where Tsipras is a Policy Fellow this spring.
“We are seeing historical changes in the world that affect not only the geopolitical balance of power and the post-war liberal international order, but democracy itself,” said Tsipras, who currently serves as a member of the Hellenic Parliament for the SYRIZA-Progressive Alliance party.
He noted that the post-Cold War international order led not only to unfairly distributed growth but to the deregulation of financial markets, culminating in the global and European financial crises. He also said that the West had “underestimated the warnings that Russia would respond militarily if NATO insisted on adopting an open-door policy on Ukraine and Georgia in 2008.” U.S. engagement in the region has not allowed for the pivot to the Indo-Pacific to take place, leaving more space for China, “not only in the South China Sea but globally.”
These developments have heralded “a shift from a unipolar to a multipolar world in which the United States remains the most powerful force but has lost its dominance,” Tsipras said. To counter, the U.S. is “disengaging itself from any obligation toward Europe and promoting a logic of might makes right.”
“We are seeing historical changes in the world that affect not only the geopolitical balance of power and the post-war liberal international order, but democracy itself.”
Alexis Tsipras
Tsipras called for Europe to enhance its strategic autonomy while retaining trans-Atlantic dialogue regardless of NATO’s future. “I believe strongly that Europe can and should use its common foreign and security policy to play a role not only of deterrence, but also as a force for peace and stability particularly in regions where NATO should not or cannot be present,” he said.
Tsipras then named several strategic goals. These include an EU — not NATO — strategy for Ukraine that brings “peace with the best possible terms for Kyiv,” enforced by an international peacekeeping force, as well as a future that gives Ukraine the choice to “move toward the EU.” He also called for an end to Israel’s bombing in Gaza, as well as the resumption of talks for a two-state solution. He stressed the need for a clear message to Turkey, and said that the “unacceptable” recent arrest of opposition leader and mayor of Istanbul, Ekrem İmamoğlu, must have consequences. “We cannot convince anyone, particularly in the Global South, of our principles if we prove to have double standards,” he said.
For Europe’s economy, Tsipras outlined four policy proposals. First, he referred to Germany’s €900 billion fiscal package as a permanent break from Wolfgang Schäuble’s ordoliberal mindset, reflecting how much faster Europe would have exited the economic crisis if this mindset had been abandoned 15 years ago. He proposed “raising the debt threshold for all member states to around 100 percent.”
His second proposal called for Germany’s new fiscal approach to be leveraged “in a way that benefits Europe as a whole, rather than being used to subsidize domestic firms of bigger countries.”
His third proposal was for “the EU to supplement its common monetary policy with a federal fiscal instrument. A treasury department, just like the United States, as any other successful monetary union does.”
This federal treasury department could be empowered “to issue common European debt to finance the strategic autonomy of the EU on energy and defense, to facilitate the green transition, to promote research and innovation, to restore Europe’s crumbling network infrastructure, and, more importantly, to increase our cohesion funds and to reduce inequalities through investments in the welfare state and education.”
“The EU needs a deepening of its internal market, on the basis of the Draghi and Letta Reports,” he concluded.
Tsipras moved on to the challenges facing EU cohesion. In recent years, he said, political parties have facilitated the rise of nationalist and extreme far right parties. “Conservative parties have adopted the rhetoric and policies of the extreme right to keep their votes. Center-left parties are seen as elitist and disconnected from the middle and working class. And left parties have been absorbed by doctrine and petty politics.” He said the lack of a comprehensive European migration policy has also contributed to the rise of the extreme right.
Returning to the issue of debt, Tsipras reiterated that fiscal solidarity and rebuilding are more important than an imaginary bottom line. “If it is necessary to finance not only the rearming of Europe, but also innovation, growth, and cohesion, then this is something that we’ll have to do,” he said.
“Europe must be a force both for deterrence and for peace,” Tsipras concluded. “The best option is to stand on our feet. That means to strengthen our internal markets, to strengthen our cohesion and convergence, and, of course, to decide for strategic autonomy, which means a common external policy and policy of defense.”
Lowell House Opera performs “Postcard from Morocco” by Dominick Argento. Baritone Marcus Schenck (center) and cast share the stage in the Lowell House dining hall, which has been transformed into a train station.Photos by Niles Singer/Harvard Staff Photographer
Campus & Community
A ride on the Marrakesh Express
Niles Singer
Harvard Staff Photographer
April 4, 2025
2 min read
‘Postcard from Mor
Lowell House Opera performs “Postcard from Morocco” by Dominick Argento. Baritone Marcus Schenck (center) and cast share the stage in the Lowell House dining hall, which has been transformed into a train station.
‘Postcard from Morocco’ brings opera back to Lowell House
After an eight-year hiatus, Lowell House Opera returned to its historical performance space — the Lowell House dining hall — with a production of “Postcard from Morocco.” Set in a train station in 1914, the opera explores the human mind through seven travelers, each of whom is characterized by a possession.
The February performances marked the company’s homecoming after having moved their productions to other campus venues during the two-year renovation of Lowell House, with COVID-19 causing a further delay.
For its winter performance, set designers used stained glass film to cover the dining hall’s windows and had colored lights cast architectural shadows; together they transformed the space into a bustling train station.
“We really value an equal playing field for seasoned professionals and emerging artists,” said Benjamin Rossen ’23, the Lowell House Opera’s executive director, as well as “Postcard’s” music director and conductor.
Among the show’s cast, orchestra, and crew are Harvard students, alumni, a faculty member, professional opera singers, and students from several Boston-area schools.
Planning for the show started in the summer of 2024. Between mid-January and opening night on Feb. 21, performers rehearsed three to four hours a day to prepare for their roles.
“The performers inhabited their roles with astonishing ease,” said stage director Haley Stark ’25. “With minimal direction, they brought their characters to life in ways that felt deeply intuitive.”
The Lowell House Opera is already working on its next production, “Parade in Concert: The Trial Behind the Tragedy,” in collaboration with Harvard Hillel. Performances will be held at Harvard Hillel on April 26-27.
Conductor and music director Benjamin T. Rossen ’23 leads the orchestra.Coloratura soprano Chen Wine sings “A Lady With a Hand Mirror.”
Marcus Schenck (top) and tenor Leo Balkovetz perform a scene together.
Alicia Chu ’28 in her role as “a foreign singer.”
Leo Balkovetz (left) and Chen Wine embrace during their performance.A dramatic moment draws the audience’s full attention.
Health
How to take yourself less seriously
Illustration by Harry Haysom/Ikon Images
April 3, 2025
4 min read
Clinical psychologist draws line between self-deprecating humor (with its health, social benefits) and self-flagellation
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
Natalie Dattilo is an instructo
There are many categories of humor. Self-deprecating humor is its own category.
I use laughter and humor when treating people struggling with depression and anxiety. Self-deprecating humor can be useful in a clinical setting. I use it myself to show its power and invite connection. For example, I’m a mom and I’m constantly saying, “mom failing,” and things like that. I think that’s fine because to call yourself out like that provides a bit of the unexpected and sends the message that it’s OK not to take yourself so seriously. Bringing humor into that conversation is also beneficial because of the safety it signals. Humor lightens the load or defuses the intensity of that moment, and can help facilitate emotion regulation, which will help you re-establish some sense of clarity and perspective.
The term self-deprecating humor makes it sound much more negative than it is. For me, it is not making fun of yourself; it is taking yourself, or the situation that you’re in, less seriously. People who tend to use self-deprecating humor effectively are quite humble and self-aware. These are people who see themselves for who they are, for better or worse, and they have come to accept that. It signals some level of self-confidence. There is an openness and willingness to be vulnerable. It also highlights the likability of people who don’t take themselves very seriously.
Learning how to take yourself less seriously without putting yourself down is important.
What’s interesting about the use of self-deprecating humor is that it’s almost somewhat spontaneous, which can be very revealing. The language being used can sometimes be indicative of somebody who is coming from a place of hurt or low self-esteem. Extreme self-criticism and the use of very harsh language to talk about yourself, including the tone and the context, matter.
Sometimes, self-deprecation can be used as a bid for attention. Somebody might be using what sounds like humor, but what it’s drawing from us is sympathy. It may also be a little off-putting on the receivers. When you’re saying something that you think is funny, but other people are like, “Oh, that’s not funny,” then do a closer look within to see where some of that is originating from, and what’s the hope in expressing that. Also, when we take ourselves too seriously or take the situations that we find ourselves in too seriously, it can create a feedback loop, in which we are feeling negatively about ourselves and putting negativity out and having that also fed back to us.
Learning how to take yourself less seriously without putting yourself down is important. If you say something that comes into your mind, and you think it’s funny, when you say it, does it make you feel better, or does it make you feel worse? Or does it elicit the response that you were hoping for?
It’s interesting to note that self-deprecating humor tends to be more common in individualistic cultures, while collective cultures often make fun of others. Western cultures put more emphasis on relatability and approachability; being able to have people relate to you by signaling flaws and vulnerabilities sends the message that everybody has struggles and we are all in this together. Cultures that are more collective tend to poke fun at one another because there’s a different sense of community. It’s the same way in which you’d would poke fun at your sibling. It’s good-natured, and it’s not meant to cause ill or harm.
I see a lot of us taking things to an extreme in a way that’s not helpful and probably not healthy. Taking ourselves less seriously is a tool to bring us back into some better balance, either within ourselves or with other people. As an example, think about two people who disagree deeply about something and have trouble connecting with each other. In those situations, finding common ground through something that may be humorous could be a game-changer. That sounds like I’m exaggerating the power of humor, but when we take ourselves too seriously, we end up isolating ourselves and that prevents us from connecting with others.
Health
Researchers ID 17 risk factors shared by age-related brain disease
Liana Wait
Mass General Brigham Communications
April 3, 2025
4 min read
Study finds that modifying one factor can reduce risk of stroke, dementia, and late-life depression
Seventeen modifiable factors have been identified that can lower people’s risk of age-related brain diseases such as stroke, dementia, and late
Researchers ID 17 risk factors shared by age-related brain disease
Liana Wait
Mass General Brigham Communications
4 min read
Study finds that modifying one factor can reduce risk of stroke, dementia, and late-life depression
Seventeen modifiable factors have been identified that can lower people’s risk of age-related brain diseases such as stroke, dementia, and late-life depression, according to researchers at Harvard-affiliated Mass General Brigham.
The study found a reduced risk of all three conditions by modifying any one of the 17 factors. The results, which provide evidence to inform novel tools, such as the Brain Care Score, are published in the Journal of Neurology, Neurosurgery, and Psychiatry.
The researchers systematically searched the scientific literature for previously published meta-analyses of risk factors associated with stroke, dementia, and late-life depression. Then, they combined these data to identify modifiable risk factors (i.e., those that can be altered through behavioral change) shared amongst at least two out of the three diseases. They also estimated the relative impact of each risk factor on measures of quality of life and early death.
Altogether, the researchers identified risk factors shared by at least two of the diseases, including blood pressure, kidney disease, fasting plasma glucose, total cholesterol, alcohol use, diet, hearing loss, pain, physical activity, purpose in life, sleep, smoking, social engagement, and stress. Of these, high blood pressure and severe kidney disease had the biggest impact on the incidence and burden of stroke, dementia, and late-life depression.
Diabetes
Diabetes is a risk factor for stroke, dementia, and depression.
Blood Pressure
High blood pressure is a major risk factor for all three conditions.
Kidney Disease
Kidney disease can increase the risk of stroke, dementia, and depression.
Fasting Plasma Glucose
High blood sugar levels, as indicated by fasting plasma glucose, are a risk factor.
Total Cholesterol
High cholesterol levels can increase the risk of stroke and dementia.
Alcohol Use
Excessive alcohol consumption is linked to increased risk of stroke, dementia, and depression.
Diet
A poor diet can contribute to the development of all three conditions.
Hearing Loss
Hearing loss is a modifiable risk factor for dementia.
Pain
Chronic pain can increase the risk of depression and potentially other conditions.
Physical Activity
Lack of physical activity is a risk factor for all three conditions.
Purpose in Life
A lack of purpose in life can contribute to depression and potentially other conditions.
Sleep
Poor sleep quality and quantity can increase the risk of depression and potentially other conditions.
Smoking
Smoking is a major risk factor for stroke, dementia, and depression.
Social Engagement
Lack of social engagement can contribute to depression and potentially other conditions.
Stress
Chronic stress can increase the risk of depression and potentially other conditions.
Depression
Untreated depression can increase the risk of other conditions.
Obesity
Obesity is a risk factor for stroke, dementia, and depression.
In contrast, physical activity and engagement in leisure activities with a cognitive aspect (e.g., puzzles) were associated with a lower risk of disease, though the researchers suspect that these associations may be symptomatic rather than causal, since individuals with brain disease may be less capable of engaging in physical and cognitive leisure activities.
“Dementia, stroke, and late-life depression are connected and intertwined, so if you develop one of them, there’s a substantial chance you may develop another one in the future,” said first author Jasper Senff, postdoctoral fellow at the Singh Lab at the Brain Care Labs at Mass General Hospital and at Harvard Medical School. “And because they share these overlapping risk factors, preventive efforts could lead to a reduction in the incidence of more than one of these diseases, which provides an opportunity to simultaneously reduce the burden of age-related brain diseases.”
Mass General Brigham researchers developed and validated the Brain Care Score to measure efforts to protect brain health and offer guidance on how to improve it. The researchers have updated the Brain Care Score to reflect the latest scientific findings. They emphasize the need for more studies on modifiable risk factors of late-life depression and call for a randomized controlled trial to test an intervention using the Brain Care Score.
“Healthcare is increasingly complex. But these findings remind us that preventing disease can be very simple. Why? Because many of the most common diseases share the same risk factors,” said Jonathan Rosand, a professor of neurology at Harvard Medical School, founder of the Global Brain Care Coalition, and the JP Kistler Endowed Chair in Neurology at MGH.
Photos by Veasey Conway/Harvard Staff Photographer
Arts & Culture
Patricia Lockwood wants you to admit the internet is real life
In Harvard talk, author riffs on ‘cloistered’ upbringing, crafting characters through dialogue, working in bed vs. on couch
Eileen O’Grady
Harvard Staff Writer
April 3, 2025
5 min read
Patricia Lockwood thinks people are uncomfortable with the idea that the
Patricia Lockwood wants you to admit the internet is real life
In Harvard talk, author riffs on ‘cloistered’ upbringing, crafting characters through dialogue, working in bed vs. on couch
Eileen O’Grady
Harvard Staff Writer
5 min read
Patricia Lockwood thinks people are uncomfortable with the idea that the internet is real life. It’s why she believes novels about the internet — including her 2021 book, “No One Is Talking About This,” about a social media star whose online life gets upended by a family emergency — are often dismissed as frivolous.
“Honestly, it made people malfunction, like they didn’t know what to do,” Lockwood said about her debut novel at a recent Writers Speak event hosted by the Mahindra Humanities Center. “There was still this idea that the internet couldn’t be in a book, and that really fascinated me.”
The discomfort, she theorized, stems from people perceiving their own online lives as private and embarrassing. To admit that the internet is real life is to admit a person’s online self is their authentic self, Lockwood told the Fong Auditorium audience.
The poet, novelist, and author of the 2017 memoir “Priestdaddy,” who is known for her sharp literary voice and irreverent social media presence, spoke with FAS Assistant Professor of English Tara K. Menon about crafting characters, writing long-form in an era of micro-content, and the art of inhabiting another writer’s mind.
“I think it’s worthwhile to spend your life reading and writing, and I think it’s worthwhile studying the way other people did those things,” said Lockwood, adding that, given a free day, she would probably spend eight hours of it reading.
Patricia Lockwood (right) with moderator Tara K. Menon.
Lockwood’s characters are vivid and complex on the page and in real life — none more so than her father, a gun-loving Navy veteran who became a Catholic priest despite being married with five children. Whether writing about him, or fictional characters, she said capturing their dialogue was key.
“If I can reproduce the speech patterns of my parents, if I can write down those odd turns of phrase, you have them,” Lockwood said. “You don’t necessarily need their interiority — because I don’t have that, I don’t understand why they do anything — but I know how they sound, and I know how they interact with each other, and I know how they interact with me.”
Lockwood said her extremely “cloistered” upbringing in the rectory where her family lived after her father became a priest helped her to keenly observe the world.
“I didn’t get out into the world the way that people did, so my encounters with it felt rare or cherished,” she said. “Walking around Harvard Square becomes a very, very rare experience, and you notice all aspects of it. If you notice all aspects, you set them down. That’s how it works for me.”
“I do it [literary criticism] because it is some sort of celestial homework. I do feel like you are working through someone’s mind.”
Lockwood, who didn’t go to college, said that exploring literature on her own gave her a sense of freedom that has helped rather than hindered her as a writer. She could choose her own translations of Tolstoy and not read any ancillary material and biographies if they weren’t interesting to her.
“I didn’t have anxiety about interpretation, really,” Lockwood said. “I was experiencing them as production of a mind, and I was trying to project myself into that mind, into that capability, from a very young age.”
Her preference is to write propped up in bed, notebook on her knees and a cat by her side, but chronic migraines have forced her to adopt a more ergonomic setup. These days, Lockwood writes perched at the end of one couch, legs stretched onto another. She demonstrated her signature posture on a sofa that was hastily dragged onstage, to the delight of the audience.
Menon so admires Lockwood’s literary criticism, especially her searing review of John Updike in the London Review of Books, that she compiled a list of what makes Lockwood such a good critic.
“One thing that I feel has become more and more rare is that you’re not afraid to do two things: say something is good or bad or a failure, and say whether you liked it or didn’t like it,” Menon said. “Even more impressive if you didn’t.”
“I do it because it is some sort of celestial homework,” Lockwood said. “I do feel like you are working through someone’s mind. You’re entering those times, how they thought, and you’re entering their talent. If you feel your own talent to be limited, it’s like you take on their abilities for a time. It’s really this transmutation. It’s amazing. You go above your own height.”
During the Q&A session, an audience member asked Lockwood if the form of the novel can survive in an era of micro-content and shrinking attention spans. Lockwood answered that some people welcome long-form fiction even when surrounded by micro-content. She cautioned against trying to find a prescription for shrinking attention spans or adopting new literary forms to follow a perceived trend.
“I don’t think that because we write this way online, that this is the appetite,” Lockwood said. “I think that the novel creates appetites. If you like the ‘fat,’ stick with the fat, you don’t have to sear that away. People who need solace, people who need to flee from that fragmentation, go to people like you for that sort of thing.”
Nation & World
Envisioning a country with no Dept. of Education
Panelist Neal McCluskey, who favors abolishing the Department of Education, expressed concern over the government’s “haphazard” methods.Photos by Niles Singer/Harvard Staff Photographer
Liz Mineo
Harvard Staff Writer
April 2, 2025
4 min read
Panelists weigh potential consequences of Trump plan to eliminate agency, transfer authori
Panelist Neal McCluskey, who favors abolishing the Department of Education, expressed concern over the government’s “haphazard” methods.
Photos by Niles Singer/Harvard Staff Photographer
Liz Mineo
Harvard Staff Writer
4 min read
Panelists weigh potential consequences of Trump plan to eliminate agency, transfer authority to states
A panel of experts convened Tuesday at the Graduate School of Education to weigh the potential consequences of President Donald Trump’s executive order to dismantle the Department of Education.
A cabinet-level executive branch agency, the department oversees policy, administers federal funding for schools, and ensures equal access to education. It also manages federal student aid programs, including Pell grants, supports research, and collects data. The agency oversees a budget of nearly $80 billion, of which about $34 billion helps low-income students and students with disabilities. It also manages more than $1.6 trillion in student loans.
In the days since the president’s order to “facilitate the closure of the Department of Education and return education authority to the states,” the agency, led by Linda McMahon, has canceled research contracts and cut staff by nearly half. Democratic attorneys general, teachers’ unions, and education organizations, among others, have filed 19 separate lawsuits challenging the administration’s education agenda, arguing that the move to close down the agency is an illegal overreach. The department was created by an act of Congress in 1979, and opponents of the Trump order say that shutting it down would also require congressional action.
Martin West (from left), Brian Gill, Catherine Lhamon, Neal McCluskey, and Andrew Rotherham.
Educators, students, and families find themselves in a confusing and unsettling environment, said Martin West, Henry Lee Shattuck Professor of Education, who moderated the conversation.
Neal McCluskey, director of the Center for Educational Freedom at the Cato Institute, favors abolishing the agency and restoring control of public schools to the states, but was critical of the government’s methods.
“My biggest concern is that this is being done so haphazardly — like a bull in a china shop,” he said. “I want to see the Department of Education go away, but if it’s done without any planning, in a way that is haphazard, that is just chaos, I’m afraid that it’ll make it look like what I want is horrendous.”
Andrew Rotherham, co-founder and senior partner at Bellwether, a national educational nonprofit, highlighted the potential fallout of lost funds in high-poverty areas across the country. Through Title I, the department provides financial assistance to schools with high numbers of children from low-income families.
“You’re obviously going to see impacts in high-poverty school districts,” said Rotherham. “In terms of the politics of this, it’s important to remember that that money gets spent in red communities, blue communities, red states, blue states, purple states. Everyone’s affected.”
“It’s important to remember that that money gets spent in red communities, blue communities, red states, blue states, purple states. Everyone’s affected.”
Andrew Rotherham, Bellwether
Catherine Lhamon, a former Ed Department assistant secretary for civil rights, lamented the implications for regional civil rights offices, which are responsible for enforcing protections guaranteed by the Constitution and federal law. Seven of 12 offices have been shuttered, she said.
“That means that fewer than half of the investigators who are struggling to do the work already are now left to do the entire nation’s civil rights enforcement work, and to guarantee that no one experiences discrimination based on race, sex, and disability in schools,” said Lhamon. “When I left on Jan. 20, our staff were carrying on average 50 cases per person, which is an untenable caseload.”
She added: “What we know is that schools are incubators for how to be in the world, how to participate in democracy, and how to be effective in our communities. … We are walking away from six decades of commitments to core protections for who each of us is. I find that terrifying.”
The panelists also voiced concerns about cuts to research administered through the agency’s Institute of Education Sciences, which has seen more than 100 layoffs. Brian Gill, a senior fellow at Mathematica, noted that his organization last month saw the cancelation of several projects contracted by the institute. The long-term effects are a big worry, he said.
“Changes to research aren’t going to have immediate effects in schools,” Gill said. “In the research world, it’s been a big deal. If you care about developing research and new programs in education, and making the schools work better in the long term, this is likely to matter.”
Arts & Culture
For 100 years, a top stop for the world’s medievalists
Sean Gilsdorf, administrative director of the Committee on Medieval Studies, delivers opening remarks in Sanders Theatre.Photos by Veasey Conway/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
April 2, 2025
4 min read
800 academics convened in Harvard Yard for workshops, presentations, and discussion
For 100 years, a top stop for the world’s medievalists
Sean Gilsdorf, administrative director of the Committee on Medieval Studies, delivers opening remarks in Sanders Theatre.
Photos by Veasey Conway/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
4 min read
800 academics convened in Harvard Yard for workshops, presentations, and discussion
The spread of misinformation online may feel like a modern problem. But more than 600 years ago, Geoffrey Chaucer, author of “The Canterbury Tales,” worried about the same thing.
According to Fernanda García-Oteyza, a Ph.D. candidate in religion at the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences, echoes of Chaucer’s Middle-English poem “The House of Fame,” where rumor is depicted as an uncontrollable force of distortion, can be found in Patricia Lockwood’s “No One Is Talking About This” (2021), a contemporary novel about the internet’s ability to alter truth and destroy literary voice.
“Both Lockwood and Chaucer take up questions of poetic authority, creativity, and inspiration, poking at the troubled relationship between reality and fiction, between rumor and fame, diving headfirst into the cacophony of speech that produces them all,” García-Oteyza explained to an audience at Sever Hall.
“It’s very exciting to be bringing the Medieval Academy back to our home and to be able to demonstrate how medieval studies has changed and grown over the past hundred years.”
Sean Gilsdorf
García-Oteyza was one of nearly two dozen Harvard students who presented at the Medieval Academy of America’s 100th annual meeting in late March. The gathering is a top destination for medievalists worldwide. This time around, more than 800 academics representing 23 countries convened in Harvard Yard for a three-day conference featuring 500 speakers, plenary addresses, workshops, exhibits, and concerts.
“It’s been really fascinating to see how interdisciplinary the field is,” García-Oteyza said of her first medieval studies-focused conference. “It’s been really generative, I’ve been able to meet a lot of people, and recognize faces that I’ve seen on book jackets.”
Elena Shadrina lectured on medieval trade agreements.
The event was a homecoming, of sorts, for the Medieval Academy of America, established in Cambridge and Boston in the early 1920s. The conference was last held on Harvard’s campus for the 50th anniversary in 1975.
“It’s very exciting to be bringing the Medieval Academy back to our home and to be able to demonstrate how medieval studies has changed and grown over the past hundred years,” said Sean Gilsdorf, administrative director of the Committee on Medieval Studies at Harvard as well as a lecturer on medieval studies and co-chair of the conference’s program committee. “These historical moments offer a really great opportunity to think retrospectively but also to think prospectively. Where are we going as a field? What’s the scholarship that’s going to move us into the next century?”
This year’s conference reflected the field’s expanding global scope, with presentations of papers on the medieval worlds of the Mediterranean, the British Isles, Scandinavia, Africa, Central and East Asia, and Islamic regions. A daylong pedagogy workshop on teaching the Global Middle Ages, organized by Assistant Professor of English Anna Wilson, encouraged graduate students to think more globally as medievalists.
Elena Shadrina, Ph.D. candidate in the History Department, presented her research on medieval Venetian trade agreements, focusing on how verbal contracts, witnesses, and forms of written documentation were used by merchants before implementation of an official register system. Colin Brady, Ph.D. candidate in the Department of Celtic Languages and Literatures, presented his work on the revival of the Óenach Tailteann (Tailteann Games) regional assembly and sporting festival in 10th-century Ireland.
Emily Sun, Ph.D. candidate in the Department of English, presented her research on Meghan Purvis’ 2013 translation of “Beowulf,” focusing on Purvis’ perspective as an American woman approaching the Old English poem from across geographical and cultural distance. After the COVID-19 lockdowns, Sun said, she has renewed appreciation for attending conferences such as this one. These events provide opportunities to bring her work beyond the computer screen and into real conversations with other academics.
“This is a big part of what scholarship actually is — meeting your bibliography and having colleagues and professors and scholars from all rungs of the ladder at panels with you, watching your papers, and giving you ideas,” Sun said. “Seeing the recurring cast of characters who also happen to be your scholarly heroes is amazing.”
Nation & World
Lesson No. 1: It pays to be nice to your allies
Nicholas Burns.Photo by Grace DuVal
Christina Pazzanese
Harvard Staff Writer
April 2, 2025
long read
Nicholas Burns on being U.S. envoy to China, returning to Harvard, lessons from long career in diplomacy
It was a challenging tour of duty.
Ambassador Nicholas Burns makes his return this week to teaching at Harvard Ken
Nicholas Burns on being U.S. envoy to China, returning to Harvard, lessons from long career in diplomacy
It was a challenging tour of duty.
Ambassador Nicholas Burns makes his return this week to teaching at Harvard Kennedy School after being tapped in 2021 to serve as the U.S. representative to China. Though U.S.-China relations historically are complicated, Burns’ tenure in Beijing came at a particularly difficult time.
Both countries were grappling with the pandemic, and while the U.S. economy slowly recovered, China’s faltered under its Zero COVID policy. The Biden administration imposed new, tougher sanctions on China over its human rights violations and limited exports of critical technology like semiconductors.
In this edited conversation, Burns, the Roy and Barbara Goodman Family Professor of the Practice of Diplomacy and International Relations, spoke to the Gazette about his experience and about what gives the U.S. a strategic advantage over China.
Relations between China and the U.S. were particularly strained during your time as U.S. ambassador. What compelled you to leave Harvard to take on something this difficult?
I had been in the career Foreign Service for 27 years and then came to Harvard for 13 years. So public service was the main mission of my career, and it’s something that I found great value in and enjoyed.
When President Biden called me just after the 2020 election to ask me to go, how could I say no? First of all, I deeply believe in public service. Second, the U.S.-China relationship is one of the most important, if not the most important, relationship we have, and highly problematic, challenging, competitive, disputatious.
I felt it was a unique opportunity to get back into government, to go back into what Teddy Roosevelt called “the arena of public service.” I had been urging all of my students for many years to go into that arena, and I felt if I’m being asked, I’ve got to go, too. I’m very grateful for the opportunity. It was, in many ways, the most difficult job I’ve ever had, and in many ways, the most worthwhile, as well.
What made it worthwhile?
It’s a consequential relationship for both countries. China is our most important competitor in the world. It’s the second-largest economy; it’s the second-strongest military power next to us; it’s our strongest adversary and competitor in the world. A lot is riding on how we manage that relationship for the decades ahead.
In addition to the military and technology and trade competitions, we have competing ideas and opposite ideas about human freedom, about democracy, about human rights, and the ability of people to speak out. The lack of freedoms in China and increasingly repressive and fearful environment made the agenda between us extraordinarily difficult and contested.
How challenging was it to communicate U.S. policy and values to the Chinese people? Are they aware they have less freedom than others around the world?
They’re very much aware that they don’t have access to free information unless you have a virtual private network (VPN), which most Chinese don’t have.
They’re in a phase of Chinese history where a highly educated public does not have a complete view of its own history, and they’re not aware of dissenting views that might contradict and criticize Chinese Communist practices. That’s a major hill to climb if you’re a government like ours that is trying to both manage a difficult and competitive relationship with the government and have a relationship between our society and 1.4 billion Chinese.
So, we spent a lot of time trying to relate and connect with the Chinese people. The Chinese government puts enormous resources into its vast propaganda network to distort our history, to distort what our president or secretary of state was saying or doing, or what I was saying or doing, and we faced a high degree of censorship on Chinese social media. We were trying to get free and fair and factual information into the Chinese bloodstream, and the communist authorities were trying to keep it out.
I had a chance to visit many universities, to speak with many professors and many students. After a couple of minutes, people are frank. It was not that everybody agreed with us. Sometimes in those sessions with students or faculty, I would face a lot of criticism, but I thought that was fair. I came from a university environment here at Harvard. I’m used to the classroom. You want students to speak up, and I certainly felt that students in China had a right to speak up, and sometimes they were very grateful for the opportunity to talk to an American and were very admiring of many parts of the culture. Sometimes they were very critical. But just having the dialogue, I thought, was a step forward and having connection.
What was the most rewarding or the most difficult part of the job?
The most difficult was dealing with the Chinese authorities on issues where we have entirely opposite views, sometimes a different interpretation of the facts, sometimes a different set of facts. That made it hard to negotiate.
We brought speakers; we brought American artists, musicians, sports figures to China to show the Chinese people this side of American culture.
In 2024, my last full year there, on 98 separate occasions, the Chinese authorities interfered with those public diplomacy people-to-people efforts. They actually turned off the electricity in a hall where an American musical group was going to perform. They would actively warn Chinese students not to come to seminars or writers’ workshops.
So that set of problems — not agreeing on the same facts, having wildly different interpretation of facts, active measures taken by the Chinese government to disrupt normal programs that any two countries would want to have with each other — that was the most frustrating part of the job.
The most rewarding was to stand by the flag again, to be back in government, to represent the United States as ambassador in this extraordinarily important country to us and to work alongside the men and women of Mission China. That was the best part of the job, being part of that team, being the leader of that team, working alongside them, and being proud of what they represent for our country.
Is diplomacy any different today from when you first joined the State Department in 1980?
There’s an aspect of diplomacy that remains unchanged. Especially in a difficult relationship like the U.S. and China, you want to make sure that each capital has a very sophisticated and detailed understanding of the other’s position on issues and of their motivations, good or bad. That hasn’t changed.
What has changed is communications technology, and the news cycle now is 24 hours a day. It comes from a million different sources. There’s much more transparency. There’s a greater obligation, certainly in the United States and democratic countries, to be open with their publics and to describe exactly what we’re doing and not to hide as many things as were hidden in the past. That’s something that we should be very good at.
That’s why I think it’s been a major mistake to try to deconstruct the federal workforce over the last couple of months, to abolish USAID, a great organization doing necessary and very important things for the American people around the world, and to take away Radio Free Europe/Liberty Radio, Radio Free Asia. Millions of people listen to those in authoritarian countries. It’s information that tells the truth about our society and about events that are happening in the world. I’m really concerned that we’re giving China an enormous propaganda advantage here, because we’re creating a vacuum.
“NATO is one of the most important institutions in American history. The fact that we’ve been able to lead it allowed us to keep the peace in the Cold War for five and a half decades.”
You once served as U.S. ambassador to NATO. At HKS, you were faculty chair of the Project on the Transatlantic Relationship. Where is that relationship today?
One of the key lessons I learned in a long diplomatic career is: Be nice to your allies and be faithful to them because they’re multipliers of American power and influence in the world. I certainly saw that at NATO on Sept. 11, 2001, when I was a very new ambassador.
The Canadian ambassador, David Wright, came to me hours after the attack, and said, “We should invoke Article Five of the NATO Treaty.” And within 24 hours, the Europeans and Canadians came to our defense.
They are the best allies we could hope to have. They share our values, and they share our interests. My job in China was made easier by the fact that the NATO countries were acting with us to try to constrain and limit what the Chinese could do in their very aggressive expansion of their own power.
NATO is one of the most important institutions in American history. The fact that we’ve been able to lead it allowed us to keep the peace in the Cold War for five and a half decades. Putin is trying to divide Europe. There’s no question that Russia, if it gets away with its crimes in Ukraine, if it’s a lenient peace agreement that favors Russian interests, then that will simply encourage Putin to be aggressive against Ukraine again, against Moldova, against the Baltic countries (now members of NATO), Estonia, Latvia, Lithuania.
So, there are enormous stakes for the United States in being tough-minded with Russia. Everyone wants the war to end, and I agree that it should end. Let’s try to end the war but negotiate it in a way that makes it far more likely that Putin will be constrained and limited in the future and not emboldened.
How does our relationship with European and East Asian allies affect U.S.-China relations?
China has no real allies in the world. We have over 30 treaty allies in Europe and five treaty allies in the Indo Pacific. This is what gives the United States strategic advantage over China that will play out over the next 10 to 20 to 30 years. It will be one of the most important stories in American history if we are able to retain our strength and protect our democracy and protect democracy around the world, because we deter Chinese aggression.
It would be a mistake of historic proportions to forsake our Indo-Pacific allies and NATO and give up the leadership role that we’ve had. I don’t think the American people will support doing that, and certainly, I don’t think most of our elected politicians in Congress would support it.
“Our mission, particularly at the Kennedy School, is to encourage bright young women and men to go into public service. That mission is more important than ever right now given everything that’s happening in Washington.“
How does it feel to be back at Harvard?
I’m really grateful to return to Harvard. I loved teaching at the Kennedy School. We have a first-rate faculty; we have outstanding students from over 90 countries all around the world. I learned so much from them when I was a professor here, and I’m really pleased to come back.
I’m going to reconstitute the Future of Diplomacy Project to make sure that we’re bringing diplomacy into our studies about global affairs. I’m going to teach a joint course next year with Professor Jim Sebenius of Harvard Business School on negotiations and diplomacy.
It’s one of the greatest institutions I’ve been involved with, and it’s doing great good in the world. Our mission, particularly at the Kennedy School, is to encourage bright young women and men to go into public service. That mission is more important than ever right now given everything that’s happening in Washington.
It’s certainly understandable if students here and elsewhere would feel that a public service career is no longer available to them. Our job is to encourage students, to understand that at the municipal level, at the state level, at the national level, and at the global level, we need good people to go into public service. That is not going to change. The pendulum in the United States, at some point, will swing back to honor public service as we have always done in our history.
Researcher Peteris Lazovskis holds a Trellis Air membrane.
Science & Tech
AC use to surge as world gets hotter. Harvard startup has a solution.
Novel system works like a coffee filter to dry, cool air more efficiently
Harvard Office of Technology Development Communications
April 2, 2025
7 min read
Today, systems that cool buildings account for as much as 4 percent of global greenhouse gas emiss
AC use to surge as world gets hotter. Harvard startup has a solution.
Novel system works like a coffee filter to dry, cool air more efficiently
Harvard Office of Technology Development Communications
7 min read
Today, systems that cool buildings account for as much as 4 percent of global greenhouse gas emissions. That may seem like a small fraction, but it’s significant: double the emissions associated with all air travel, for example.
As the world gets hotter due to climate change, the need for cooling is set to rise substantially. Air conditioning demand is expected to soar by up to 40 percent by 2030. Energy use, and the associated climate-warming emissions, will balloon along with it.
“There’s a climate-change solution here,” said Jonathan Grinham, assistant professor of architecture at Harvard’s Graduate School of Design. “The problem is big, and the market opportunity is big.”
Despite the revolution coming for demand, the technology used to cool spaces has remained relatively stagnant for more than a century. “We’ve lived in the status quo of the bigger industries delivering the same vapor-compression technology,” said Grinham.
Trellis Air, a Harvard startup, is set to disrupt that status quo. Thanks to collaborative efforts from across the University, the company recently launched with aims to drastically reduce the energy needed to run air conditioners with its novel approach to dehumidification.
‘Marriage of raw science and engineering breakthroughs’
Most air conditioners are not all that different from souped-up dehumidifiers. A cooling system pulls in room-temperature air and chills it using chemicals called refrigerants. Water vapor separated from the air is condensed — resulting in that “drip, drip, drip” that air conditioners are notorious for — while the cooler air is released into a room and heat is diverted outside.
Air-conditioning technology also makes air drier, and dehumidifiers use a similar process to condense water out of ambient air. The cool, dry air is then rewarmed and released back into the room.
“A dehumidifier burns a lot of energy,” said Russ Wilcox, Trellis Air CEO. “It’s like driving with one foot on the gas, the other foot on the brake: You’ve got one part making cold, the other part making heat.”
While refrigerants — which have significant planet-warming potential of their own — are at the core of most modern cooling systems, some industrial facilities that need incredibly dry air may also choose what’s called a desiccant air dryer, a system that uses a material like salt to absorb water.
Trellis Air, on the other hand, will rely on a “third way,” of pulling moisture from the air, said Wilcox. Harvard scientists developed a unique membrane capable of separating water vapor directly from the air — similar to a coffee filter. The system uses much less energy than traditional air conditioners and dehumidifiers and is more stable than desiccant systems.
A Trellis Air prototype, pictured alongside a traditional AC unit, is tested in Miami.
To develop the underlying tech, Grinham worked closely with staff scientist Jack Alvarenga and others in the lab of Joanna Aizenberg, the Amy Smith Berylson Professor of Materials Science at Harvard’s John A. Paulson School of Engineering and Applied Sciences (SEAS) and professor of chemistry and chemical biology at Harvard. Leveraging his deep expertise in architecture and building science, Grinham collaborated with Alvarenga and other researchers in the Aizenberg Lab to prototype materials and conduct the foundational science needed to create Trellis Air’s product.
Membrane dehumidification systems have been attempted in the past, but struggled to achieve high-water selectivity with scalable and robust materials. In addition to developing a workable membrane, the Harvard team designed a novel, 3D-printed tile assembly that allows water to readily pass through while protecting the delicate membrane, which is just 15 microns thick — thinner than a human hair — for long periods of time.
“It was this really nice marriage of raw science and engineering breakthroughs,” said Christopher Petty, OTD’s director of business development for physical sciences.
‘If he says something is worth seeing, it’s usually worth seeing’
OTD protected the intellectual property of the innovations developed at Harvard and licensed it to Trellis Air for further development. Grinham and Alvarenga will stay involved as scientific advisers to the company, as will Aizenberg and Martin Bechthold from the School of Design.
Petty, a former entrepreneur himself, wasn’t initially familiar with the type of tech Grinham and the research team set out to develop. But what he learned about the scope of the air conditioning challenge stunned him, and convinced him of the business’s potential.
“Sometimes it’s enough that it’s a good business, it has to be,” says Petty. “But if you feel you can work on something that might have that kind of impact, then it helps you sleep at night too.”
He began networking to find an entrepreneur who could shepherd the idea from technological breakthrough to big-time business.
Wilcox, an entrepreneur turned venture capitalist who had previously popularized the electronic paper-display technology that’s today used in millions of Kindles, was among Petty’s early calls. And his interest was immediately piqued. “If he says something is worth seeing, it’s usually worth seeing,” says Wilcox.
Still, it took more than a dozen meetings before Wilcox decided to become the company’s CEO. Wilcox was convinced from the beginning that the opportunity was a huge one, due to the sheer size of the AC industry, but he decided to make the jump after learning that several past colleagues from his former company, E Ink, were willing to sign on with him.
Starting a company that he believed in with past coworkers “just seemed like the most joyful thing I could do,” he said. “Nothing could be more exciting.”
Wilcox sees three roads to commercialization for Trellis Air: replacing desiccant systems in industrial applications, swapping basement dehumidifiers for more efficient models, and the big-time bet: integrating Trellis Air’s technology with air conditioners across the world. Wilcox says the company will pitch the tech as a “pre-drying module” that will allow ACs to run much more efficiently, consuming much less energy.
The CEO has backed nearly two dozen companies as an investor, and sees big possibilities for Trellis Air, in part because of the huge potential reward. “In order for a deep-tech startup to work, you need a big, bold goal that everyone will decide is worth the risk,” he said. The scope of the air conditioning challenge fits the bill.
To de-risk the tech and show that it can work, Trellis Air has spent the past year prototyping. Before the company launched, a proof-of-concept prototype was piloted in Miami through the team’s Department of Energy Grant with Forrest Meggers at Princeton University and Les Norford at MIT. Next, the team tested a fully integrated system at Harvard’s HouseZero, the headquarters of the Harvard Center for Green Buildings and Cities, retrofitted as a “living lab” to test and collect data on the technology’s efficiency in a real-world setting. These demonstrations showed what Trellis Air’s tech can do in Boston’s hot, humid summers and the even more inhospitable Miami climate.
Those real-world examples should help give funders confidence in the system’s capabilities.
“It’s one thing to build energy models to say that this is possible, and it’s a whole other thing to actually deliver the physical prototype at scale,” said Alvarenga. “We were able to bring the idea into existence inside the lab and then move beyond the lab into pilot field studies. With Trellis Air we want to go further and scale up a commercial product that can meaningfully reduce the future massive energy and emissions needs of cooling.”
Harvard IP licensed to Trellis Air was funded in part by the Department of Energy and National Science Foundation.
Robert Brustein in 2004.Harvard file photo
Campus & Community
Robert Sanford Brustein, 96
Memorial Minute — Faculty of Arts and Sciences
April 2, 2025
6 min read
At a meeting of the Faculty of Arts and Sciences on April 1, 2025, the following tribute to the life and service of the late Robert Sanford Brustein was spread upon the permanent records of the Faculty.
The legacy and influence of Robert
At a meeting of the Faculty of Arts and Sciences on April 1, 2025, the following tribute to the life and service of the late Robert Sanford Brustein was spread upon the permanent records of the Faculty.
The legacy and influence of Robert Brustein, a major presence in American theater of the 20th century, live on in the 21st. As dean of the Yale School of Drama starting in 1966, Brustein founded the Yale Repertory Theatre, where he worked with playwrights such as Sam Shepherd and David Mamet and with players such as Meryl Streep. In 1980 at Harvard, he became director of the Loeb Drama Center and turned it into the home of the American Repertory Theater (A.R.T.). He later founded the Institute for Advanced Theater Training. While at Harvard, Brustein also taught as a full professor of English. He retired in 2003, becoming a research professor of English and creative consultant to the A.R.T.
While Brustein’s command of drama, from ancient Greek plays to avant-garde theater, was legendary, he was always a theatrical innovator, seeking and creating genuinely new, profound productions. He was a leader in the regional theater movement, which emphasized serious, intelligent engagement with past great authors and newly rising ones. His founding of repertory companies at Yale and Harvard established fresh relationships between research universities and the performing arts, a model copied at other schools. In 1990 he told The New York Times, “The basic aim of the commercial theater is to make a profit” and “the basic aim of noncommercial theater, in its ideal form, is to create the condition whereby works of art can be known. And I don’t think these are compatible aims.”
Brustein believed deeply in textual criticism of plays and honored their interpretations both as literary works and as fluid dramas that demand different performances for different times. Coming to Harvard, he apparently worried that the institution might not always support theater of high quality. President Derek Bok was said to have given that guarantee. The joke was that if the box office did not provide enough for the A.R.T., then Bok’s Office would. Brustein’s concerns were not without merit. Two early A.R.T. productions witnessed audiences leave midway through performances, but he was willing to accept such risks to achieve unique qualities that a calculated, commercial theater could rarely equal.
At the A.R.T., Brustein succeeded in melding performance, scholarship, and dramaturgy, while bringing together professionals, amateurs, and students. Under his leadership, the A.R.T. championed directors such as Alvin Epstein, JoAnne Akalaitis, Peter Sellars, Julie Taymor, and Robert Wilson. Despite a demanding national and international schedule, Brustein regularly gave lecture courses on modern or post-modern drama from 1980 through 2001.
The current artistic director of the A.R.T., Diane Paulus, became acquainted with Brustein’s work when she was an undergraduate at Harvard. She thinks that his vision for theater remains bold and innovative. Sam Marks, a senior lecturer on playwriting in the Department of English, notes, “Not only does he leave an immense legacy in the theater, he changed the lives of so many of his students, whom he loved.”
Born in Brooklyn on April 21, 1927, the son of the businessman Max Brustein and the former Blanche Haft, Brustein grew up in Manhattan, attended the High School of Music and Art, then graduated from Amherst College. During college, he took time off to serve in the Merchant Marine. After receiving an M.A. in dramatic literature from Columbia University and two years at the University of Nottingham on a Fulbright fellowship, he pursued the Ph.D. at Columbia, then taught at Columbia, Vassar College, and Cornell University.
In 1964 Brustein published “The Theatre of Revolt,” a critical study. His publications are remarkably extensive. With his leading genres the review or chapter essay, he authored more than a dozen books, chapters in volumes edited by others, scores of reviews, articles in learned journals, a comedy about Shakespeare and Marlowe, and an autobiographical play, “Spring Forward, Fall Back.” His other plays include “Nobody Dies on Friday,” which satirizes the acting teacher Lee Strasberg, and “Shlemiel the First,” a klezmer musical based on stories by Isaac Bashevis Singer.
Beginning in 1959, Brustein was a drama critic for The New Republic for 46 years. He contributed reviews and essays to The New York Review of Books. Among his books, one should mention “Letters to a Young Actor,” a variation on Rilke’s “Letters to a Young Poet.” Brustein advised young actors to obtain a broad liberal arts education rather than a narrow professional one. He edited Strindberg. Other favorite playwrights included Ibsen, O’Neill, Genet, Pirandello, and Shaw, all of whom he treated in “The Theater of Revolt” and whose works he showcased at the A.R.T. He continued to publish until shortly before his death, which occurred at his home in Cambridge, Massachusetts, on Oct. 29, 2023.
Brustein’s energy and productivity in directing, producing, teaching, mentoring, and writing were astounding. Feisty, he sometimes created controversy but to those encounters always brought opinions informed by knowledge, theatrical experience, and scholarly research. He seemed, at times unusually, to love the heat of friction. The more prominent his opponent, the grittier became his sandpaper.
Brustein and Samuel Beckett clashed over Akalaitis’s version of the set for Beckett’s “Endgame” at the A.R.T. Brustein retorted, “To threaten any deviations from a purist rendering of this or any other play . . . not only robs collaborating artists of their interpretive freedom but threatens to turn the theater into a waxworks.” Brustein also disputed with August Wilson about the nature and scope of Black theater in the United States.
Later in life, Brustein criticized what he believed was a renewed, even vicious, American worship of money and success, along with a concomitant decline in integrity, intelligence, and soul. He believed similar forces were eroding American theater. To The Boston Globe, he remarked in 2012, “I think the American theater reflects America now, as everything that happens is beginning to reflect America — one-percent America.”
First married to Norma Ofstrock, who died in 1979, Brustein in 1996 married Doreen Beinart, who survives him, as do his son, Daniel Brustein, stepchildren, and several grandchildren and step-grandchildren.
Diane Macdonald/Getty Images
Health
Mortality rates between Black, white Americans narrow — except in case of infants
70-year study finds widening gap despite longer life expectancy for both racial groups
Anna Gibbs
Harvard Correspondent
April 1, 2025
5 min read
Americans are living longer than ever. And the disparity in overall mortality rates between Black and white Americans has narrow
Mortality rates between Black, white Americans narrow — except in case of infants
70-year study finds widening gap despite longer life expectancy for both racial groups
Anna Gibbs
Harvard Correspondent
5 min read
Americans are living longer than ever. And the disparity in overall mortality rates between Black and white Americans has narrowed since the 1950s. Among infants, however, the gap has widened, with Black infants dying at twice the rate of white infants, a new study reports.
A team of researchers, including Associate Professor Soroush Saghafian, founder and director of the Public Impact Analytics Science Lab at Harvard, collected and analyzed data across the U.S. from 1950 to 2019 to determine how mortality rates and disparities have changed over time.
In general, life expectancy has improved for both Black Americans (from 60.5 years in the 1950s to 76 years in the 2010s, a 20.4 percent increase) and white Americans (from 69 years in the 1950s to 79.3 years in the 2010s, a 13 percent rise), according to the new research. The racial gap has also improved, though Black adults still have an 18 percent higher mortality rate.
The picture for Black infants is far bleaker. While mortality rates for both Black and white infants have improved, the disparity between races has worsened. The mortality rate for Black infants was 92 percent higher than for white infants in the 1950s. Today the difference is 115 percent. Medical conditions during pregnancy were the leading cause of excess death in the 2010s.
In this edited conversation, Saghafian explains where these disparities have persisted and what needs to happen to address them.
Soroush Saghafian.
Photo by Grace DuVal
Life expectancy has been improving for 70 years, and yet the difference between mortality in Black and white infants has actually gotten worse. What’s happened since the 1950s?
There is a public understanding that healthcare has improved over time in the U.S., and that life expectancy and other healthcare metrics are improving. This study is showing that, while all that is true, there have been gaps between different races, specifically between Black and white Americans.
When focusing on adults, we see that, fortunately, things have improved. But in the case of Black infants, they are now dying twice as often as white infants. That’s just a huge number. And the fact that it has worsened since the 1950s is of great concern. Public policy and public health authorities should have put their utmost priority on at least improving such gaps. I mean, the ideal is to make measures like this equal between different races. But at least you can improve things.
What accounts for the disparity in infant rates?
We did look at the causes of death, and it turns out that, for infants, the main reasons for excess mortalities are medical. There is, unfortunately, a large amount of healthcare inequality, and it’s multidimensional. There’s access to care, but also quality of care. There’s a large set of factors that cause these disparities.
However, the goal of this particular study was not to study the reasons, but to point out the important differences. The hope is that it can inform other studies to get to the reasons, and to inform policymakers about what they should do. Our work raises the critical question of why, over seven decades post-World War II, we still haven’t figured out a solution for this enormous problem.
“This is like a red alarm. Our findings are saying: Look, we could have saved 5 million Black Americans if they had the same things as white Americans have.”
Several shorter-span studies have also found mortality rate disparities between races. What does this study tell us that the others didn’t?
This is, to the best of my knowledge, the first time that the whole data over seven decades — the entire postwar era — has been collected and analyzed. When you look at shorter periods, you might not get the full picture.
Looking at a more extended period, we can think more carefully about all the claims that say, “Look, healthcare is improving” — which, to be clear, is mostly true. We are still seeing that, by and large, healthcare is improving for both Black and white Americans in most dimensions.
The problem is the comparisons. For instance, are things getting better for Black people compared to white people? When we look at measures like excess infant and childhood mortality among Black Americans during this whole seven-decade period, it becomes clear that not only have things not improved, but they have gotten worse. However, if you looked at, say, only three decades, instead of seven, you might not be able to see this full picture.
Your results showed that 5 million excess deaths of Black Americans could’ve been avoided over the past 70 years.Now that the disparities have been laid out, what needs to happen next?
As I mentioned, we didn’t go into the details of the causes, and I think that needs a lot more attention from both researchers and public policy and public health authorities. At the same time, our findings raise important questions for both researchers and authorities.
This is like a red alarm. Our findings are saying: Look, we could have saved 5 million Black Americans if they had the same things as white Americans have. This, in turn, raises an important question: What should the priorities for public policy and public health officials be now and in the next few decades?
Giang Nguyen (left) and Robin Glover. File photo by Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Healthy Minds Survey asks students about mental health
University will use results to tailor resources and support to students’ needs
Nicole Rura
Harvard Correspondent
April 1, 2025
6 min read
On Wednesday the University will launch the Healthy Minds Survey, which asks
Healthy Minds Survey asks students about mental health
University will use results to tailor resources and support to students’ needs
Nicole Rura
Harvard Correspondent
6 min read
On Wednesday the University will launch the Healthy Minds Survey, which asks all degree-seeking undergraduate and graduate students about their current mental health, as well as their awareness and utilization of Harvard’s mental health resources and support. Sponsored by the Provost Office of Student Affairs and University Health Services, the confidential survey will be open until April 23.
The survey, developed at the University of Michigan and administered at hundreds of colleges and universities across the country, will provide Harvard with national benchmarking data to gauge progress and evaluate challenges related to student mental health. It is one of a series of steps Harvard has taken in response to the University’s Report of the Task Force on Managing Student Mental Health released in 2020.
To learn more about the survey and how the University will use its results, the Gazette sat down with Robin Glover, associate provost for student affairs, and Giang Nguyen, associate provost for campus health and well-being and executive director of Harvard University Health Services.
What is the Healthy Minds Survey?
Glover: The Healthy Minds Survey is a national survey based at the University of Michigan that has provided data for more than 15 years on the mental health of students in colleges and universities across the U.S. It includes a lot of the questions that we wanted to ask our students about their mental health and whether the resources and support we’re currently offering meet students’ needs. Without asking, we don’t really know how we’re doing. All of this information will inform decisions about any changes to the services and support we provide to our students.
Nguyen: The Healthy Minds Survey will also help us evaluate where we stand within the context of the broader mental health needs of college and university students all over the country. While the University has recently administered other surveys, such as the HESMA and Pulse surveys, Healthy Minds is the only University-wide survey specifically focused on student mental health and benchmarked against other universities.
How will the survey’s results be used?
Nguyen: In response to previous assessments of the student mental health experience, we improved student access to mental health support by implementing the 24/7 CAMHS Cares phone support line, providing access to TimelyCare for virtual mental health visits, and implementing a new clinical access coordinator team staffed by CAMHS licensed clinicians. We’ve also implemented campus-wide educational programs for members of our community to address mental health needs. Through the Healthy Minds Survey, we want to know whether our students know that these resources exist, what their experience has been with them, and which resources should be added or strengthened.
Periodically surveying students about their experiences and needs regarding health, and specifically mental health, is good public health practice. So, we will likely be conducting additional surveys every three years in the future.
Why is this survey important, and why should students take it?
Glover: We are really encouraging every student who is invited — every undergraduate and graduate student — to complete the survey. We want to hear as many different voices from as many different perspectives as possible. This will give us a complete picture of the mental health status of our students, as well as feedback about the programs that we offer here. A broad response across the University is important because an undergraduate student is different from a graduate student, and a professional student at the Medical School is different from one at the Business School.
What type of questions will be included and how long will it take?
Nguyen: In addition to asking about awareness and utilization of mental health services on campus, we do ask students to anonymously share with us their own experiences with mental health, which may include questions about depression, anxiety, body image issues, or other mental health diagnoses. We also ask questions about how connected they are with the community around them, as well as any exposures to trauma or substance abuse in the past. All of this feedback helps us to understand, in a more direct way, the experience of our students.
Glover: In total, the survey will take about 25 minutes, and we recognize that’s a significant commitment. As a thank-you for their time, students will receive a $15 gift card after completing the survey. Students may also exit the survey at any time, or they can pause taking it and pick it up again later using their personal survey link.
Mental health can be a difficult topic. How will the responses be kept confidential?
Nguyen: The folks at the national Healthy Minds Study have been doing this since 2007. Because they know how sensitive this subject matter is for participants, they have worked out very thoughtful and careful approaches to protecting students’ privacy.
Glover: That’s correct. They are contractually committed to anonymizing all responses and will not generate or maintain any internal connection logs with IP addresses. No information linking a student’s identity to their survey response, including an incomplete survey response, will be available to Harvard, any of the other participating universities, or any other party that may have access to the anonymized data.
Why is it important for Harvard to continue to invest in student mental health awareness services and resources?
Nguyen: We know that throughout academic life, our students face challenges. These are sometimes related to campus life and sometimes related to things going on in the broader world. We want to support our students throughout their academic journey at Harvard by helping them address their well-being and developing the capacity to strengthen their well-being in all its facets. And we recognize that one of the most critical facets of well-being is emotional well-being.
Glover: Our undergraduate and graduate students are here one year, two years, five years, seven years. Harvard is their home, their community during that time. It’s up to us to make sure that we’re offering them all the services and support that ensures their well-being, and that they feel comfortable about getting those services, support, and resources, where they need it, in a timely manner, and without judgment.
It’s very important for all of us to know that mental health is just as important as physical health. If someone says they’re getting a physical examination, people don’t think twice. And we want taking care of mental health to be the same way.
Work & Economy
You, too, can never, ever relax
Illustration by Ben Sanders/Ikon Images
Jacob Sweet
Harvard Staff Writer
April 1, 2025
5 min read
In ‘Make Your Own Job,’ Erik Baker explores how entrepreneurialism has altered Americans’ relationship with work
There are lots of entrepreneurs these days. Founders of businesses, of course, are entrepreneurs, and so are the managers below
In ‘Make Your Own Job,’ Erik Baker explores how entrepreneurialism has altered Americans’ relationship with work
There are lots of entrepreneurs these days. Founders of businesses, of course, are entrepreneurs, and so are the managers below them. Ride-share drivers, influencers, life coaches: entrepreneurs. There are self-styled intrapreneurs, solopreneurs, and sidepreneurs, all of whom embody the ideals of entrepreneurialism in their own unique ways.
In “Make Your Own Job,” history of science lecturer Erik Baker explores the American embrace of entrepreneurialism and why, for all the popularity of the approach, it can feel so exhausting.
Baker got interested in the topic as his friends graduated from college, landed well-paying corporate jobs, and quickly became miserable. One told him that she felt like Natalie Portman’s character in the sci-fi movie “Annihilation,” who descends into a black pit and discovers a sinister doppelganger. There was something interesting, Baker thought, about how work changes our relationships with ourselves.
In “Make Your Own Job,” Baker traces America’s enthusiasm for entrepreneurialism to the end of the 19th century. It was the conclusion of the first era of American industrialization, and the rapid electrification of manufacturing plants, among other developments, depressed demand for factory labor. After high levels of job growth throughout the 1800s, Baker writes, “The rate of employment growth in manufacturing began to taper off in 1890 and became negative around 1920.”
Social scientists called this job loss “structural” or “technological” unemployment: “Unemployment that was not the product of transient, cyclical crises,” Baker writes, “but was rather a side effect of irreversible changes to the technical structure of American industry.”
In response, Americans shifted from an industrious work ethic to an entrepreneurial one infused with ideas of personal transcendence in New Thought. Instead of focusing on the inherent value of hard work, the new ethic emphasized that hard work wasn’t enough; one should apply one’s own unique skills to the task at hand with ceaseless ambition. A cohort of success writers, across racial and gender demographics, began preaching a similar ideology: “Make your own job.”
Baker chronicles how entrepreneurialism, and its very definition, expanded over time. In the early 1900s, orthodox management styles that focused primarily on production processes gave way to “entrepreneurial management,” which focused not on merely managing employees, but inspiring them. At Harvard Business School, among other institutions, management intellectuals preached the importance of leaders who made workers “not truly feel like subordinates,” in Baker’s words, “but like members of a team or a family, or even a revolutionary cadre.”
The new ethic emphasized that hard work wasn’t enough; one should apply one’s own unique skills to the task at hand with ceaseless ambition.
In Baker’s narrative, entrepreneurial fervor tends to increase during times of economic stress. During the Great Depression, “odd jobs” became something more. Doing freelance work was not just a way to make a few dollars, but, as the authors of the 1933 book “Make Your Own Job: Opportunities in Unusual Vocations” put it, a way for someone to build “a small one-man business of his own.” Women over 40, who often faced hiring discrimination, could embrace this individualistic ethic. “We Are Forty and We Did Get Jobs,” boasted the title of one self-help book aimed at women.
Baker uses these references to self-help literature to illustrate shifts in national sentiment. Authors such as Napoleon Hill, whose 1937 book “Think and Grow Rich” remains popular to this day, encouraged readers to turn work into a calling that relied on specialized knowledge, creativity, and self-promotion. “With the changed conditions ushered in by the world economic collapse,” Hill wrote, “came also the need for newer and better ways of marketing personal services.”
By the mid-20th century, Baker writes, interest in entrepreneurialism had surged into non-economic fields, with Abraham Maslow and other psychologists becoming cheerleaders. “The most valuable 100 people to bring into a deteriorating society,” Maslow wrote, “would be not 100 chemists, or politicians, or professors, or engineers, but rather 100 entrepreneurs.”
It also became a catch-all explanation for a lack of economic development. As the fate of American cities sharply diverged with the relocation and shuttering of factories during the 1960s, certain experts blamed increasing unemployment in places like Detroit on a lack of entrepreneurial spirit.
With these mid-century changes, Baker argues, almost everyone could think of themselves as entrepreneurs: leaders of companies, managers who could inspire their co-workers, employees who could take more initiative, and even unemployed people looking for work. “It was far from obvious that high-tech corporate executives … were doing exactly the same sort of thing as a laid-off Black worker taking adult education classes, or a shopkeeper in India contemplating a change in management methods,” Baker writes. “But midcentury thinking about entrepreneurship and development depended upon precisely this equivalence.”
In the 1970s and 1980s, it wasn’t so much a scarcity of work that drew people toward entrepreneurialism, Baker argues, but a scarcity of jobs people found meaningful. This yearning was filled in part by leaders who encouraged employees to see their work as a source of enlightenment. Apple’s Steve Jobs would state that competing with IBM was not an economic imperative but a moral one — lest IBM win and stifle innovation. Ralph Nader’s Center for Study of Responsive Law was supported by young, ambitious employees. When asked how many hours he expected them to work, Nader deadpanned: “The ideal is 100.”
The popularity of entrepreneurialism continues to this day, Baker says, in part because it glorifies a perpetual state of risk. With fears of technological job displacement rising along with the number of people in freelance or temporary roles, more people can consider themselves the center of an entrepreneurial operation — even if the operation is just themselves.
Reading “Make Your Own Job,” one can see why Baker’s friend found herself experiencing science-fiction levels of misery. When failure always feels tangible, it’s hard to relax. For Baker, entrepreneurialism requires that everyone keep a solitary eye on the future — and remain anxious in the present.
Campus & Community
Aramont Fellowships champion research at forefront of innovation
April 1, 2025
6 min read
Winning projects selected for potential to fuel scientific progress
Offering a better understanding of the universe. Revealing a possible layer of gene regulation in human cells. Treating muscular diseases with implantable neurotechnologies. These are examples of the research supported by th
Aramont Fellowships champion research at forefront of innovation
6 min read
Winning projects selected for potential to fuel scientific progress
Offering a better understanding of the universe. Revealing a possible layer of gene regulation in human cells. Treating muscular diseases with implantable neurotechnologies. These are examples of the research supported by the Aramont Fellowship Fund for Emerging Science Research, which acknowledges the visionary work of exceptional early career scientists.
Established in 2017 through a gift from the Aramont Charitable Foundation, the award recognizes groundbreaking scientific innovation and exploration by providing crucial funding for high-risk, high-reward research that otherwise might not be conducted. This year’s cohort includes five scholars spearheading projects with the potential to significantly impact their respective fields and advance novel discoveries with wide-ranging implications.
“The Aramont Fund’s transformative impact on the awardees’ work and careers is inspiring,” said Vice Provost for Research John Shaw. “Investing in our early career scholars is vital to driving scientific innovation and nurturing the next generation of researchers. We all look forward to following the newest cohort’s achievements.”
Guanhao Huang
“Exploring Gravitational Physics Using Nano-mechanics on a Chip”
Postdoctoral fellow in applied physics, Harvard John A. Paulson School of Engineering and Applied Sciences.
The nature of gravity at the quantum level and the mysterious properties of dark matter are two of the biggest open questions in modern physics. While past breakthroughs have come from large-scale international collaborations using massive scientific instruments, an exciting new approach is emerging: using nanomechanical devices in university labs to probe these mysteries. Unlike traditional methods that rely on laser-controlled individual atoms, these tiny but relatively heavy devices — often made of materials like diamonds — act as ultra-sensitive quantum force sensors and sources of gravity. This makes them uniquely suited to explore new gravitational effects at microscopic scales. Most current research focuses on only a few vibrational states and leaves many unexplored, which limits the potential for studying gravity. To overcome this challenge, Huang aims to develop ultra-precise sensors by engineering and controlling these devices at the quantum level across a broad range of vibrational states. This could open new doors for detecting dark matter and gravitational phenomena, offering fresh insights into both the microscopic and cosmic scales — all using compact, tabletop experiments within a university setting. His work has the potential to reshape the understanding of the universe in ways previously thought possible only with massive, billion-dollar facilities.
Giacomo Maddaloni
“Discovering Brain Circuits That Change Seasonally and Offer Clues to the Seasonal Exacerbation of Diseases from Neuropsychiatric to Cardiovascular”
Postdoctoral fellow in genetics, Harvard Medical School.
Credit: Ajja Photography
The ability to anticipate the light-dark cycle of the days and seasons — and to organize appropriate responses — are vital adaptive strategies that have been observed across the animal kingdom and in humans. When thrown off, the sleep-wake cycle and other biological rhythms can cause or exacerbate disease. However, little is known about the neural mechanisms underlying such adaptations. Giacomo Maddaloni has undertaken studies that led to the discovery of a previously unappreciated mouse brain circuit and form of plasticity that proves critical for synchronizing activity and sleep-wake rhythms. As part of that work, he discovered that specialized neurons function as initial broadcasters of day length information in a region of the brain that controls many behaviors and physiological processes. Now Maddaloni is expanding on this work by characterizing the neurons’ molecular identity and deciphering how they decode and relay information to orchestrate whole-organism responses. He aims to identify a master brain hub vital for accurate circadian and seasonal adaptations, and molecular and circuit pathways, with far-reaching translational therapeutic potential.
Silvi Rouskin
“Unveiling Human Riboswitches Through High Throughput Detection and Analysis”
Assistant professor of microbiology, HMS.
Credit: Gretchen Ertl
Riboswitches are dynamic RNA structures that control various metabolic pathways in simple organisms. They have not been detected in humans, which is likely due to the technical limitations of research. The discovery of human riboswitches could enable new therapeutic targets for metabolic diseases and change our understanding of how gene expression is regulated. Silvi Rouskin has already identified promising riboswitch candidates, and her unique integration of experimental and computational approaches puts her team in a strong position to make this pivotal discovery — potentially revealing a previously unrecognized layer of gene regulation in human cells. This finding would fill a critical gap in the knowledge of cellular biology and open new avenues for medical research and drug development.
Shriya Srinivasan
“Accessible Neurotechnology and Human-Machine Interfacing”
Assistant professor of bioengineering, SEAS.
Eliza Grinnell/SEAS
Implantable neurotechnologies hold promise for treating muscular diseases and are expected to be available as a consumer technology within the next 10 to 15 years, but the significant invasiveness required to implant the devices will limit accessibility and exacerbate gaps in care and capabilities. Shriya Srinivasan aims to make neurotechnology scalable and accessible by developing neurostimulation devices that can be precisely implanted through a single skin injection. Preliminary prototypes in rats have demonstrated that Srinivasan’s lab can read high-resolution neural signals and stimulate discrete muscles for fine motor control. The system can stimulate the muscles to provide sensory feedback about the movement of a prosthesis or robotic, augment forces in weak muscles, and potentially relay complex physical data through the body’s neural processing centers. The implications of Srinivasan’s project are significant for treating neuromuscular diseases, studying human sensorimotor performance, and advancing consumer technology.
Melanie Weber
“Geometry-informed Foundation Models for Scientific Machine Learning”
Assistant professor of applied mathematics and of computer science, SEAS.
Artificial intelligence is revolutionizing scientific research, with foundation models driving breakthroughs that may hold the key to challenges such as climate change or currently incurable diseases. But there are limitations: Foundation models require extensive training data and substantial amounts of computing resources, posing challenges when the data is expensive or limited. For example, a foundation model for weather prediction may need training on millions of data points to provide accurate results. Encoding data geometry, such as symmetries arising from fundamental laws of physics, could significantly reduce the data and resources needed by providing the model with information it can use to avoid wasting resources on pursuing scenarios that we know cannot exist. Melanie Weber seeks to develop geometry-informed models that balance the strengths of current geometric models and general-purpose foundation models to produce models that are both resource-efficient and applicable to a wide range of scientific problems.
Campus & Community
Civil discourse that exceeds 150 characters
Harvard Business School’s Nien-hê Hsieh (standing) posed a hypothetical to the panel.Photos by Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
March 31, 2025
6 min read
New Ethics Center events mull real-life conflicts, with first focusing on improving campus discourse on hard topics in social media ag
Harvard Business School’s Nien-hê Hsieh (standing) posed a hypothetical to the panel.
Photos by Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
6 min read
New Ethics Center events mull real-life conflicts, with first focusing on improving campus discourse on hard topics in social media age
Social media exerts a powerful influence on college campuses. Has the technology helped broker new connections across ideological difference? Or has it simply siphoned students into conversations with those who share their views?
This was the topic of last Thursday’s inaugural Ethics IRL (or, in real life,) a new series organized by the Edmond and Lily Safra Center for Ethics. Its format, inspired by the 1980s PBS show “Ethics in America,” uses the Socratic method to engage Harvard community members on pressing issues.
Things got underway with moderator Nien-hê Hsieh, the Kim B. Clark Professor of Business Administration at Harvard Business School, posing a hypothetical: Assigned reading for a general-education course covers immigration, with students required to post their responses to a class discussion board.
One student writes: “I don’t understand why people who want to defend their country are being called racist, are being called xenophobic nationalists. Since when did it become a crime to defend the borders of your country?”
“I don’t see how you can live in a country where federal agents are ripping children from the arms of their parents and families,” responds another. “This is basically state-sanctioned trauma.”
On the panel were a dean, an activist, a journalist, an influencer, and a current undergraduate who largely avoids the technology. Hsieh instructed the group to put themselves in the place of students.
“I think this prompt is missing a very important piece of context, and that is whether or not the responses posted are anonymous.”
Soleil Golden ’24
Soleil Golden.
“Would you give your honest opinion no matter what people might say in response to those posts? Would you carefully craft a neutral position and try not to attract your classmates’ attention?” he asked.
“I think this prompt is missing a very important piece of context, and that is whether or not the responses posted are anonymous,” answered Soleil Golden ’24, a premedical neuroscience student at Boston Children’s Hospital with more than 70,000 Instagram followers, who described using social media to hone her rhetorical skills. “If it’s anonymous, I think people would feel a lot freer in voicing their opinions.”
And what if the instructor pulled those comments into the lecture, pressing both students to elaborate on their positions?
“I think I’d be more inclined to speak out,” answered Brody Douglass ’27, an economics concentrator and Navy ROTC midshipman who said he limits social media in favor of in-person socializing. “I believe that, in general, better dialogue happens when it’s actually dialogue rather than just a series of discussion posts where words can be taken more easily out of context.”
Panelists offered a mix of deeply personal and evidence-based insights on the state of modern discourse. The series was introduced with support from the Faculty of Arts and Sciences Civil Discourse initiative.
“Can we imagine how this would have played out on social media?” Hsieh wondered.
“Perhaps there would have been some grains of interesting conversation,” replied researcher and activist Yaёl Eisenstat, a policy director at the Cybersecurity for Democracy project at New York University, who noted the platforms’ influence on the very formulation of the assignment. “But chances are, in the way social media is constructed today, it would have been drowned out by the more emotional.”
And what if both students were doxed? What if the resulting fear drove one to withdraw from the university entirely?
“I think would be extremely sad if the first student left,” said Sewell Chan ’98, executive editor of the Columbia Journalism Review. Speaking directly to the charge that universities have become inhospitable to conservatives, he continued: “We live in a world in which 40 percent or more of the country not only agrees with student number one but would say things much harsher. If we’re acting like we’re so offended or bothered by student number one that we can’t handle what they said, that should say something about us.”
As the conversation progressed, panelists kept returning to the tension between the goals of higher education and the algorithmically driven platforms.
“Universities have a particular mission,” explained Rakesh Khurana, Danoff Dean of Harvard College. “Their mission is to search for Veritas, as close as they can get. They do that by bringing diverse perspectives and points of view to an environment. They create certain conditions that are different than free speech conditions, which is that you can say what you want to say but you have to defend it with reason and evidence.
“I can stand outside and say, ‘The Earth is flat;’it’s perfectly within my free speech rights,” he continued. “I can say it in the classroom, but don’t expect it to get marked correct in my Earth and Planetary Sciences class.”
But Eisenstat said that social media algorithms actively undermine the pursuit Khurana described.
“The world that social media has helped create affects how students interact with each other on campus,” she argued. “What the world of social media has done is made it easier and easier to both choose your silos but also be pushed into silos that you’re not aware you’re being pushed into. … It’s the personalization. It’s the using all your human behavioral data to then turn around and target you with the information that is going to most appeal to your lizard brain.”
The event ended with panelists sharing suggestions for community members who want to help foster a climate more conducive to open exchange.
“Push yourself to engage with people who are not like-minded,” Eisenstat said. “But do not therefore think it is too hard to create the social media environment we want and to push for the legislation that would help.”
“I’ve spent hours talking to people online,” Golden said. “While those conversations can be frustrating and you can feel like you’re losing the argument, I have not engaged in any social interaction online where I haven’t walked away with a new piece of knowledge.”
“I now try to discipline myself,” Khurana said. “When I find myself disagreeing with somebody, I assume we’re plugged into different algorithms.”
Health
Exercise can help colon cancer survivors live longer
Post-treatment physical activity narrows gap between patients and general population, study shows
Dana-Farber Communications
March 31, 2025
3 min read
Regular physical activity after treatment for stage 3 colon cancer reduces and may even eliminate disparities in survival between those with cancer and those in a general population of sim
Exercise can help colon cancer survivors live longer
Post-treatment physical activity narrows gap between patients and general population, study shows
Dana-Farber Communications
3 min read
Regular physical activity after treatment for stage 3 colon cancer reduces and may even eliminate disparities in survival between those with cancer and those in a general population of similar age and sex, according to new Dana-Farber Cancer Institute research.
Colon cancer is a leading cause of cancer-related death worldwide. People with the disease face higher rates of premature death than people in the general population with matched characteristics such as age and sex.
“This study suggests that exercise can have a meaningful impact on long-term survival for patients,” said senior author Jeffrey Meyerhardt, co-director of the Colon and Rectal Care Center at Harvard-affiliated Dana-Farber and a professor at Harvard Medical School.
For patients whose cancer returned, those with low activity levels had overall survival rates 50.5 percent lower than a matched general population.
Previous research suggested that colon cancer patients who are more active after treatment have longer survival. This study looked at data from two National Cancer Institute–sponsored Cancer and Leukemia Group B clinical trials — now part of the Alliance for Clinical Trials in Oncology — for patients with stage 3 colon cancer. In both trials, CALGB 89803 and CALGB 80702, patients underwent surgery, were treated with chemotherapy, and were offered an option to self-report about lifestyle factors during and after treatment.
A total of 2,875 patients self-reported physical activity across the two trials. Survival rates were calculated after a median of six and 5.9 years of follow up, respectively, for CALGB 89803 and CALGB 80702. Reported activity levels were converted into metabolic-equivalent hours per week, or MET-hours. A person who walks most days of the week for about an hour will get about 18 MET-hours of activity, Meyerhardt said.
The researchers found that for patients who were alive three years after treatment, those with high activity levels (18 or more MET-hours per week) had subsequent overall survival rates that were closer to those of the matched general population than those with low activity levels (fewer than three MET-hours per week).
For instance, in the analysis of data from CALGB 89803, three-year survivors with low levels of activity had overall survival rates that were 17.1 percent lower than the matched general population, while those with high activity levels had 3.5 percent lower overall survival rates.
In both trials, more activity was associated with improved survival rates and the benefits were seen in patients regardless of their age at the time of diagnosis. “Some exercise is better than none,” says Meyerhardt. “If you can’t get out for an hour, try 10 or 20 minutes.”
In a pooled analysis of data from the two trials, the researchers focused on the 1,908 patients who were alive without a recurrence of their cancer after three years. Among those who reported low activity levels, overall survival rates were 3.1 percent lower than the matched general population. Those with high activity levels had overall survival rates that were 2.9 percent higher than the matched general population.
Exercise also reduced survival disparities in patients whose cancer came back within three years. Most tumor recurrences are seen within two or three years of diagnosis with stage 3 colon cancer. In these cases, treatment becomes very difficult. For patients whose cancer returned, those with low activity levels had overall survival rates 50.5 percent lower than a matched general population. Those with high activity levels had overall survival rates 33.2 percent lower.
“Those who were more active had improvements in survival even if their cancer recurred,” Meyerhardt said. “And for those who did not experience a recurrence, their overall survival rates looked better than the matched general population.”
The research described in this story received funding from the National Institutes of Health.
Historian Joyce Chaplin’s latest book on Benjamin Franklin (center) explores one of his lesser-known inventions: a stove (left). The science behind it helped further understanding of atmospheric phenomena such as the Gulf Stream (right), which Franklin helped map for the first time.Images via Library of Congress; illustration by Liz Zonarich/Harvard Staff
Science & Tech
When a stove’s virtues amount to more than just hot air
Christy DeSmith
Historian Joyce Chaplin’s latest book on Benjamin Franklin (center) explores one of his lesser-known inventions: a stove (left). The science behind it helped further understanding of atmospheric phenomena such as the Gulf Stream (right), which Franklin helped map for the first time.
Images via Library of Congress; illustration by Liz Zonarich/Harvard Staff
When a stove’s virtues amount to more than just hot air
Christy DeSmith
Harvard Staff Writer
8 min read
Science historian examines how Benjamin Franklin’s invention sparked new thinking on weather, technology
Joyce Chaplin thought she was done with Benjamin Franklin.
“But then I was reading about the Little Ice Age and the particularly bad winter of 1740 to 1741,” said Chaplin, the James Duncan Phillips Professor of Early American History. “Major harbors were reported as freezing over — in Boston, in London, in Venice. The consequence was famine in several places including Ireland, where as much as 20 percent of the population may have died — that’s a bigger toll than the more famous Great Hunger of the 19th century.
“And all along I kept thinking, ‘I know the dates 1740 and 1741 from somewhere.’”
Chaplin, an expert on early American science, technology, and medicine, eventually put things together. These were the years when Franklin — a humble printer who went on to become a world-renowned scientist, inventor, and statesman — devised the prototype for his Pennsylvania fireplace, a flatpack of iron plates colonists could assemble and insert into their hearths to improve heating.
“It was developed during this very, very cold winter as a climate adaptation,” explained Chaplin, who has written at length on Franklin’s scientific contributions. “The design was supposed to burn less wood yet make a room even warmer than an ordinary fireplace.”
Franklin went on to develop at least five separate iterations of the influential technology over half a century, moving from wood to coal for fuel. Chaplin’s newly released “The Franklin Stove: An Unintended American Revolution” finds this seemingly modest invention catalyzing new thinking on weather, technology, and comfort.
We sat down with Chaplin, who is also affiliated faculty in the History of Science Department, to ask about the book and its many lessons for the 21st century. The interview was edited for length and clarity.
Joyce Chaplin.
Stephanie Mitchell/Harvard Staff Photographer
You published an intellectual biography of Benjamin Franklin in 2006 and edited an edition of his autobiography for Norton a few years later. What draws you to this 18th-century figure time and again?
The popular conception is “Poor Richard,” Franklin’s alter ego from the almanacs he published. But he’s far more complicated than that. He was the youngest son of a Boston chandler, somebody who worked with his hands making soap and candles out of animal fat. It was a completely respectable but not very distinguished background.
The classic ways of getting ahead that were available to a man like Franklin included war or some kind of military career that would advance him beyond the rank he was born to. Politics, if he could get a foot in. Writing, perhaps. Science had also become a part of popular culture, with Isaac Newton and Robert Boyle becoming household names in the wake of their big discoveries.
I think Franklin looked over all these options. He eventually looked at Newton and thought: “Why not try that route?”
Is it fair to call the Franklin stove one of his lesser-known inventions?
For the moment, I think that’s fair. A lot of people know about Franklin inventing the lightning rod. Those who need progressive glasses at some point probably know he invented bifocals. Others have heard about his more charming inventions — his swimming fins, his folding chair/step stool for reaching books in the library. But given the climate framing of this particular invention, perhaps the public will start to embrace the stove as central to his life in science.
Let’s dig into the environmental issues Franklin faced during the winter of 1740 and ’41. It was more than frigid weather.
Franklin was aware that as more settlers were arriving, being born, and spreading across the landscape, they were going to deforest the territory and make firewood more expensive and possibly even inaccessible to the poor. We have his accounts of people stealing firewood or ripping off pieces of fences.
But the most ambitious part of his plan was to make people more comfortable than ever before. And the fact that it was colder than ever before makes that a really interesting manifestation of enlightenment confidence — that humans could use science and technology to make life better, whatever the circumstances.
“Atmosphere was a relatively new word in terms of describing the envelope around the Earth, and this is what Franklin thought a good heating system could create indoors.”
How did the stove help further understanding of the natural world?
Atmosphere was a relatively new word in terms of describing the envelope around the Earth, and this is what Franklin thought a good heating system could create indoors. He explained in a self-published pamphlet how his fireplace worked through the principle of convection: that air, when it’s warmed, will expand and rise. And what you want is some kind of heat source that does this layer by layer until the entire room is warmed.
But Franklin also used this concept to explain atmospheric phenomena outdoors. He used it to explain how storm systems move up the Atlantic coast. He eventually used it to explain the Gulf Stream — how heated air moves up from the Gulf of Mexico and out over the Atlantic Ocean with a relationship to the warmer current of water underneath. When making these grand statements, Franklin would often write something like: “Just like there’s a draft of air from your fireplace to the door.” It was a brilliant strategy for making science accessible to a reading public.
Franklin is known for his late-in-life abolitionism, but your book adds one more entry to the list of ways he profited from slavery before that. What new information did you uncover?
I knew from reading my colleague John Bezís-Selfa’s “Forging America” (2004) that there had been an iron industry in the colonies, including Pennsylvania. I also had a sense from reading Bezís-Selfa that enslaved Black people performed some of the labor on these estates.
I went to the Historical Society of Pennsylvania, which holds most of the surviving records of the Pennsylvania iron industry, and indeed found these two enslaved men — Cesar and Streaphon — who worked in the iron establishment that made most of the Pennsylvania fireplaces.
One of these men — Streaphon — managed to buy his own freedom. That, to me, was an important indication that the desire to be free was a constant. It can be seen everywhere in early American history.
What compelled Franklin to try minimizing emissions from his stove?
He was appalled at the filthy air in places like London. So, he tried to design the last three versions of his stove to re-burn smoke — by sending the smoke that would otherwise be ascending into the chimney back into the fire.
Franklin pointed out, correctly, that smoke is really particles of unburned fuel. If you could burn it again, at least it’s more efficient. You’re wasting less fuel. You’re putting less junk into the air. He’s so concerned with doing this that a friend teases him for being “a universal smoke doctor.”
To me, it’s a very interesting statement about questioning the level of emissions that already seemed to be compromising human health. Of course, what gets identified decades after his death in 1790 is that some of these emissions are invisible. The American scientific observer and experimenter Eunice Foote documented the climate-altering effects of CO2 in 1856.
You connect today’s techno-optimism to Franklin and other inventors of his era, who thought they could invent their way out of a climate crisis. What lessons does your book hold for inheritors of this philosophy?
I don’t think Franklin meant to validate burning coal in the industrial sense, but he did validate it as an energy source. That says to me: Don’t pick the quick and obvious solution. Or at least be suspicious and monitor how it’s doing.
We should be wary of this silver bullet fantasy, that we need to find just one thing to sequester carbon out of the atmosphere. Or that we can just shift to sustainable energy in the absence of climate mitigation before chemical changes in the atmosphere become too dire.
We’ll need more than one inventor, one device, one hero. There are just too many variables for one solution to be possible. We need to modify our course as soon as possible with a lot of solutions working together.
Health
Is your shirt making you sick?
Anna Lamb
Harvard Staff Writer
March 28, 2025
4 min read
ChemFORWARD, winner of Belfer Center award, explains how its database of industrial chemicals can help protect human, environmental health
Have you ever thought of the chemicals that went into making your iPhone? Your favorite pleather chair? The shirt on your back? It takes thousands of chemi
ChemFORWARD, winner of Belfer Center award, explains how its database of industrial chemicals can help protect human, environmental health
Have you ever thought of the chemicals that went into making your iPhone? Your favorite pleather chair? The shirt on your back? It takes thousands of chemicals to produce things we use every day, and some of them could be harmful to both your health and the planet’s.
Heather McKenney, the science and safer chemistry lead at ChemFORWARD, was joined by Kennedy School experts as well as David Bourne, lead sustainability strategist at Google, in a panel last week at the Kennedy School’s Malkin Penthouse to discuss the company’s work as well as challenges the private sector faces in trying to reduce chemical hazards.
“We live in a world with thousands of chemicals,” said Henry Lee, Jassim M. Jaidah Family Director of the Kennedy School’s Environment and Natural Resources Program and senior lecturer in Public Policy. “They are present in the clothes we wear, what we eat and drink, the furniture in our homes, and even in the health products that we buy. Thus, focusing on what society can do to ensure the protection of public health in this chemical-intense world is especially important.”
ChemFORWARD, a Washington D.C.-based 501c3, compiles and maintains a digital repository of “verified chemical hazard assessments,” or CHAs, available to corporate subscribers in order to make informed and environmentally sound decisions about the chemicals used in their supply chains.
“There’s no requirement across all industries that all chemicals must be vetted before use,” said McKenney, who was a lead for the toxicology and product safety team at Honest Company, a baby and beauty products maker, for six years.
“There’s no requirement across all industries that all chemicals must be vetted before use.”
Heather McKenney, ChemFORWARD
Heather McKenney and David Bourne.
Benn Craig/Belfer Center
McKenney said there are well-intentioned companies that want to certify their products as safe, but struggle keeping track of every chemical used in their supply chain, and what the impacts of those chemicals are.
“There’s tons of toxicology data out there, and how do we start to apply and share that information such that it’s not just siloed in a REACH dossier in the EU or in an individual organization who’s developed that data?” she said, referring to the EU’s Registration, Evaluation, Authorization and Restriction of Chemicals regulation. “We’ve developed a methodology that houses the chemical hazard assessments across 24-plus human and environmental health endpoints.”
On the human side, ChemFORWARD assesses a chemical’s carcinogenicity, mutagenicity, reproductive toxicity, skin irritation, eye irritation, and neurotoxicity, among other things. On the environmental side, they measure things like persistence, or the ability of chemicals to break down.
“Looking at the totality of the data, we then take the totality of the hazards and send an overall hazard classification, or what we call our hazard bands,” McKenney said.
ChemFORWARD hazard bands fall into alphabetical rankings (A, B, C, etc.,) but are also categorized based on how much data is available about a given substance. There are chemicals marked with a question mark when the data is deemed insufficient.
Bourne said companies like his are partnering with ChemFORWARD as an important step toward creating healthier products at his firm and across the private sector.
“What we realize in partnership with ChemFORWARD is that every time we do a chemical hazard assessment, it’s not just proprietary information for Google or for whoever did the assessment. It’s now available to anyone who wants to try to platform. And so the scalability that creates is really what we saw as transformational,” he said. “The analogy I like to give is if you wanted to watch a great TV show, and you had to pay a Hollywood studio to make a show just for you, it would cost you an absurd amount of money. Because they have lots of subscribers to a streaming platform, everyone can contribute and get access to a whole body of content that is valuable.”
Charles Taylor, an assistant professor of public policy at Harvard Kennedy School, said this type of information-gathering could have important benefits beyond the private sector.
“This kind of information is really important to get out to researchers and others who can … assess if we see chronic effects or downstream effects,” he said.
The Roy Family Award is presented biannually to celebrate an outstanding cross-sector partnership that enhances environmental quality through novel and creative approaches.
Illustrations by Liz Zonarich/Harvard Staff
Arts & Culture
We used to read more, scream less
How has the internet changed fiction? 8 writers weigh in.
Anna Lamb
Harvard Staff Writer
March 28, 2025
long read
Fiction is as old as time. From the ancient “Epic of Gilgamesh” to contemporary novels and short stories, fiction has explored the human condition and pushed us to think outside o
How has the internet changed fiction? 8 writers weigh in.
Anna Lamb
Harvard Staff Writer
long read
Fiction is as old as time. From the ancient “Epic of Gilgamesh” to contemporary novels and short stories, fiction has explored the human condition and pushed us to think outside ourselves and expand our imaginations. The internet, on the other hand, is less than 50 years old. It’s evolved exponentially over the last four decades, and inarguably changed the way we communicate, live, and think.
In these edited responses, writers of the genre share how they believe the internet has changed fiction.
Readers have become audiences
Greg Jackson ’06 is the author of several short stories that have appeared in The New Yorker, Granta, and the Virginia Quarterly Review. His debut novel, “The Dimensions of a Cave,” was published in 2023.
Fiction is fundamentally about one privacy addressing another. Its power and meaning depend on the writer speaking with uncomfortable candor, channeling a brave private truth, and the reader receiving this message as a solitary conscience. “Write as though your parents are dead,” writers are counseled. But in the age of the internet, writers must go further and write as though the unignorable sphere of a vast judging public did not exist. This is increasingly hard to do.
The internet — what we refer to, in shorthand, as social media — has made personal taste into a matter of public enthusiasm and, as often, condemnation. It has turned “readers” into “audiences.” Taste has become something impersonal, conditioned by influencers, likes, star ratings, Tweets, and lists. Traditional tastemakers — critics, editors, booksellers — have seen their influence overtaken by mass opinion and viral acclaim. Without them, we have few champions of challenging, difficult, and subversive work. Sensitive to their audiences’ whims and the viability of their careers, writers adapt their work to what they think a mass public wants and believes. The imperative to startle readers with what they don’t know they want, with a truth pitched at a deeper place than superficial opinion, disappears. Readers may well forget that this is what fiction offers.
Are there positives? I don’t see many and I think pairing the minuses with some pluses obscures what is, on balance, a negative equation. Sometimes a net effect is simply bad. Literature is a vital companion to self-discovery, illuminating our condition. It addresses a realm of experience prior to politics, mass conviction, commonplace belief, and rote speech. You cannot discover what you already know. Fiction’s radiant core — private truth — may well turn out to be the chief casualty of our age of social media.
A time-saver and a time-suck
Scott Turow, J.D. ’78, is a lawyer and the author of 13 fiction and three nonfiction books including “Presumed Innocent” and the memoir of his first year at Harvard Law School, “One L.”
I use the internet for research, and the ease of it is sometimes striking. In my most recent novel, “Presumed Guilty,”I learned about the minutiae of the Nike Air Force 1 sneaker and the question of how far cell signals travel, both with days less time than it would have taken me when I started out 40 years ago. Because of that, I think my books are probably more research-intensive than they would have been decades ago.
Fiction exists on the assumption that we can learn the inmost thoughts and feelings of others. That people have an appetite for learning that is no surprise, but it makes storytelling a profoundly moral enterprise, because it sharpens our empathy for others. I don’t think posts or emails generally have the same depth.
The internet obviously competes for readers’ time, and I think it’s true that book sales began to drop when people started “cruising the net,” as it used to be called when people just gave themselves over to wandering through the online world. But the internet carries benefits as well, especially the easy accessibility of eBooks. Readers connect online and share word-of-mouth about books they like. So, it’s not all one way.
The one thing I am sure of is that the novel has withstood technological changes since the 18th century — or the 13th century, depending on how you figure its birth. And it’s not going away soon.
We lost a major plot device
Jennifer Finney Boylan was the 2022-2023 Marilyn Beaudry-Corbett Schlesinger Fellow at Harvard Radcliffe Institute. She is the author of 19 books, including her latest, “Cleavage” (2025), president of PEN America, and the inaugural Anna Quindlen Writer in Residence at Barnard College of Columbia University.
A major plot hook used to be people losing each other, or getting lost, or not knowing where they were, and so on. And this particular situation is now one that’s very unlikely — since we’re always tied into the web somehow. Think of the film “After Hours” (by Martin Scorsese), in which Griffin Dunne’s money flies out of a taxicab window one night and he’s then left stranded downtown, unable to get home. This kind of twist is pretty rare now, isn’t it? And if you think about it, so many great stories — from the “Odyssey” to, say, “Ulysses” — are about people who have gotten lost, or who are trying to find their way home, and the obstacles to their journey consist of not knowing where they are, or being unable to tell their loved ones of their fate.
In my heart I think we’d all have been better off if the internet — and the iPhone and its knockoffs — had never been invented. We would spend more of our time looking at each other, rather than our screens. We would read more, scream less. Is that world so much worse than the one we live in now?
A time machine for research
Julie Orringer was the 2013-2014 Lisa Goldberg Fellow at Harvard Radcliffe Institute. She is the author of three award-winning books: “The Invisible Bridge,” “How to Breathe Underwater” and “The Flight Portfolio,” a novel about Harvard alumnus Varian Fry, an American journalist who traveled to France in 1940 to save writers and artists blacklisted by the Gestapo. Her work has also appeared in Granta and The Scribner Anthology of American Short Fiction, and she is the winner of The Paris Review’s Plimpton Prize.
Two things that have been really helpful to research are doors that open via the internet. One is newspaper archives. It’s incredibly helpful to be able to go into Times Machine via The New York Times, for example, and look at the newspaper pages exactly as they were laid out and to see the article that you’re trying to read in context, and for that article to be searchable. It used to be that researchers would have to go and look at microfilm, which was just impossible. And so you can page through the day-by-day events of a particular historical moment, but also you get all the context of the other articles, and the ads for hats and suits and foods and theater shows and modes of transportation, and a lot of the other kind of contextual cues that would help to place you in a particular temporal setting.
And then the other thing that I’ve found that’s similarly helpful is radio archives, because we tend to forget what a constant presence radio was in people’s lives, especially when we’re writing about the 20th century. And there are numerous archives that allow you access to the radio shows that people were listening to regularly every day. If you don’t hear the voices that were speaking into people’s ears about the political events and the artistic events and the fashions of a time, then you don’t really have the whole picture.
Less time at the library, for better and for worse
Weike Wang ’11 is the author of several novels, including “Chemistry,” “Joan is Okay,” and “Rental House.” She is the recipient of a PEN/Hemingway Award, a Whiting Award, and a National Book Foundation 5 under 35. Her work has appeared in Ploughshares, The New Yorker, The Atlantic, and The Best American Short Stories, and she has won an O. Henry Award.
I learned to read at the library. My mother would take me and she would be in the adult section, looking through job listings in newspapers, and I would be in the kids section, reading “Anne of Green Gables” or “Goosebumps” and playing the Oregon Trail. I’m not sure if the internet changed fiction but it changed reading. Without the internet or a phone with internet access, I read for longer, deeper periods. I would spend whole days reading. Now I can’t do that. Also I have more responsibilities and reading has become part of my job rather than my leisure.
The internet has certainly made research easier for stories. Instead of going to the library, I can find more things online. I can Google. I can watch YouTube videos. I also can use Google Maps to see what the area I’m writing about looks like. Without the internet, I would have to go there. I would also have to interview people if I’m interested in writing a character with that occupation. Nowadays, so many people post online about their experiences that writers have easy access to this kind of material.
We need emotional truth too
Min Jin Lee was the 2018-2019 Catherine A. and Mary C. Gellert Fellow at Harvard Radcliffe Institute. She is the author of the novels “Free Food for Millionaires” and “Pachinko,” a finalist for the National Book Award, runner-up for the Dayton Literary Peace Prize, and a New York Times “100 Best Books of the 21st Century.” Lee is also the 2024 recipient of The Fitzgerald Prize for Literary Excellence.
Apart from the fact that the internet may have contributed to the Oxford English Dictionary 2024 Word of the Year, “brain rot,” and that neoliberalism has made our attention the commodity to exploit without mercy, I remain unreasonably hopeful that fiction will emerge as the primary vehicle of enduring narrative. We may love nonfiction in many of its forms, but fiction has the capacity to enlarge our grasp of emotional truth through the prism of non-fact.
Expanding knowledge
Andrè Aciman, Ph.D. ’88, is the author of several New York Times bestselling novels, including “Call Me by Your Name,” “Out of Egypt,” and “Eight White Nights.” He’s the editor of The Proust Project and teaches comparative literature at the Graduate Center of the City University of New York.
Books are important. They mold who you are, and they give you an aperture into history and into the universe that is not available elsewhere. Does “Crime and Punishment” give you a better sense of who human beings are? Absolutely. Does Shakespeare? Yes. But a small article on the net that appears and then disappears? That’s the way people think nowadays, and I have no argument against it.
My experience has been that young people, people under 35 with the exception of a few, don’t read or they are constantly online, reading the newspaper, the magazines. They know all sorts of things that I would never have even imagined existed. I, on the other hand, know nothing except for what I read in The New York Times, and I don’t even read that very thoughtfully. My sons, for example, seem to know so much, as all their friends do, but none of them read books.
Some things ‘can only be experienced through face-to-face interactions’
Yxta Maya Murray is the current Walter Jackson Bate Fellow at Harvard Radcliffe Institute, a law professor, writer, social practice artist, and beginning filmmaker. She also is the David P. Leonard Professor of Law at Loyola Law School, where she writes legal scholarship examining the relationship among law, social justice, and the arts. She has published 11 books.
I have written several novels that are steeped in legal, scientific and archival research. And these books would have been impossible for me without the internet. My 2020 book, “The World Doesn’t Work that Way, but It Could” is a collection of stories reflecting President Donald Trump rolling back the administrative state, by which I mean unraveling safety regulations in the Department of the Interior and EPA. I did legal and scientific research and asked the web to deliver me reports. But the research alone can’t enliven the text. There are things that are not available on the web, and that can only be experienced through face-to-face interactions. So I did interviews. Fiction is important so that we can imagine other people’s lives, so that we can develop empathy, so that we can move outside of ourselves, and we can see ourselves mirrored. It’s galactically important, because only a very small part of reality can be expressed, and if you confine yourself to nonfiction and are trying to do a good ethical job of that, then you strangle the ability to express all sorts of other parts of human experience.
Arts & Culture
Uncovering the palette of the past
Jinah Kim.Photo by Grace DuVal
Eileen O’Grady
Harvard Staff Writer
March 28, 2025
7 min read
Project maps pigments used in South Asian art
When Jinah Kim learned in 2016 that Museum of Fine Arts conservation scientist Michele Derrick had detected cobalt in a 15th-century Indian manuscript, she was presented with an obvious explanation
When Jinah Kim learned in 2016 that Museum of Fine Arts conservation scientist Michele Derrick had detected cobalt in a 15th-century Indian manuscript, she was presented with an obvious explanation: the document had probably been retouched later, potentially with synthetic pigments. After all, European-made cobalt-based pigments like smalt were widely imported to South Asia only in the 17th century, and synthetic cobalt blue was popularized only in the early 19th century.
But Kim, who was gathering data on pigments as research for her second book, wasn’t convinced.
“What do we know about actual pigment usage in this region at this time period?” Kim, George P. Bickford Professor of Indian and South Asian Art in the Department of History of Art & Architecture, asked herself. “Does it all have to come from Europe? It’s possible there are indigenous knowledge of colorants that we don’t know about.”
Further analysis by Katherine Eremin, Patricia Cornwell Senior Conservation Scientist at Harvard Art Museums, confirmed that the smalt found in the Jain manuscript had a different composition from European-manufactured smalt, indicating it came from a different source.
It was a “eureka” moment for Kim, who hypothesized that some pigments believed to have gotten to South Asia as imports from Europe may in fact have been used in South Asia long before. The result was the “Mapping Color in History Project,” an ongoing effort since 2018 to create an object-based pigment database for historical research on art from this region.
“I realized a lot of pigment databases available out there are based on a Western European canon, because that’s where the research has been,” Kim said. “If you look at Asian materials, especially South Asia, Himalaya, and Southeast Asia, everything is so colorful but the baseline understanding of what colorants were available is not known.”
“I realized a lot of pigment databases available out there are based on a Western European canon, because that’s where the research has been.”
Jinah Kim
The open-access database allows users to search by painting title, keyword, pigment, color, or element, and filter results by artist, date, and more. There’s also a map to search by location of origin. On each artwork’s page, users can view an analysis of what pigments were found in the painting, what method was used to identify them, and the scientists’ confidence level. Kim wants the database to be useful for “anyone interested in color,” including people in the cultural heritage field, art historians, curators, teachers, and students.
Kim describes Mapping History as highly collaborative, bringing together experts in digital humanities, conservation science, and art history.
“I do describe it as a three-legged stool,” Kim said. “It cannot be done by one person because it requires a lot of different expertise. You need to do computer programming to make this database, you need to work with material analysis, and you need art historical research to map it in history and time.”
“Hindu Goddess Ganga with Two Female Attendants Carrying Fly-Whisks,” Harvard Art Museums/Arthur M. Sackler Museum, Gift of James E. Robinson III in honor of Stuart Cary Welch and Alve John Erickson
Kim worked with Rashmi Singhal and the Arts & Humanities Research Computing (DARTH) team and Jeff Steward from Harvard Art Museums on the technology aspects of the project. The database was built from scratch.
Tracy Stuber, digital humanities specialist with DARTH who acts as bridge between the research teams and software engineers, said the Mapping Color website is unique because it links two types of data that are usually siloed and used by separate audiences: data about the artwork itself and data about the scientific analysis.
“Because we know approximately where or when an artwork was made, we’re then able to say, ‘This pigment that we’ve identified in this artwork was therefore made approximately in that place at that time,’” Stuber said. “Linking them together in a database not only makes that data accessible to the other audience but facilitates more collaboration and conversation between those two disciplines.”
Katherine Eremin (left) and Jinah Kim observe a manuscript under a microscope.
Photos by Grace DuVal
Working with ancient art means that scientists can’t usually take samples for analysis. Mapping Color’s scientists rely 99% of the time on non-destructive methods, according to Eremin, who is one of the project’s core partners.
When Eremin analyzes an artwork, she typically starts with imaging which can identify certain pigments that behave differently in infrared and ultraviolet lights. Indian Yellow, for example, glows under UV light. She also examines the pigment under a microscope to see the blend of colors used.
“You look at them to begin with and you think, ‘Oh that’s beautiful,’ but then you actually look down the microscope and see the really fine details,” she said. “You think, ‘that’s just blue,’ and then you look at it and see that actually it’s lots of different things mixed together.”
She will then try to identify elements using x-ray fluorescence to see what characteristic x-rays are emitted from the painting. For example, a green can be identified as copper green if there are visible copper rays, or yellow orpiment (an arsenic sulfide mineral) blended with blue if there are visible arsenic rays. To gather information at the molecular level, Eremin uses Raman spectroscopy, a non-invasive laser technology which can reveal if a copper green is either malachite or atacamite.
On rare occasions if an artwork is already flaking, it may begin a conversation between conservators, curators, and scientists about whether to take a sample. Eremin used an infrared light technique known as Fourier-Transform Infrared Spectroscopy on one tiny particle taken from a crumbling 16th-century Indian manuscript, and identified that kaolin clay was used for the white border detail.
The findings give insight into the vision of the artists. In an analysis of a 1588 “Divan of Anvari” manuscript series, Mapping Color scientists realized the artist used an Indian yellow pigment for the pure yellow of figure’s clothing, but used orpiment, an older arsenic sulfide yellow, for highlighting leaves on a tree.
“What that tells me is that artists are trying to get to that pure form of brilliant yellow, and they’re discerning between different shades,” Kim said.
“Krishna’s Manifest Vision through Sound (Kavitt),” from a Rasikapriya series, Harvard Art Museums/Arthur M. Sackler Museum, Gift of Philip Hofer
With support from the Lakshmi Mittal and Family South Asia Institute, the Mapping Color in History Project has also collaborated with Jaipur-based traditional Indian painter Babulal Marotia to analyze samples of pigments he uses in his studio. It’s helpful to study materials used by contemporary artists like Marotia, who are carrying on artistic traditions that have been passed down for generations, according to Kim.
“You can’t dissolve a 700-year-old painting to see what has happened.” Kim said. “This gives us an access point to that historical moment through this type of material that’s still being used.”
Mapping the origin locations of the paintings in the database isn’t easy, as historic paintings from South Asia often lack precise information about the date, location, and artist.
Mapping the origin locations of the paintings in the database isn’t easy, as historic paintings from South Asia often lack precise information about the date, location, and artist.
“If you look up certain Indian painting in a museum’s database, it will say, ‘North India, 17th-18th century,” Kim said. “You cannot map “North India, 17th -18th century” in any point in time and place. That’s where we need to do more research on objects, find more relevant information and answer comparative studies to narrow it down and come up with better attribution.”
Kim has a list of ideas for how to improve the database (adding more artworks, visualization tools, and certainty indicators) that she is excited to implement.
“I want to understand certain trends, I want to be able to see patterns, I want to see things that were not visible before,” Kim said. “But a database is only as good as the data itself, so there’s a lot of work that still needs to go in.”
Some of the work on the database was supported by grants from the National Endowment for the Humanities.
Arts & Culture
An architect-detective’s medieval mystery
Photos by Justin Knight; photo illustration by Liz Zonarich/Harvard Staff
Sy Boles
Harvard Staff Writer
March 27, 2025
6 min read
Exhibit traces scholar’s quest to reconstruct abbey destroyed after French Revolution
Cluny III, once the largest building in Europe, was little more than rubble when Harvard architectural historian
Photos by Justin Knight; photo illustration by Liz Zonarich/Harvard Staff
Sy Boles
Harvard Staff Writer
6 min read
Exhibit traces scholar’s quest to reconstruct abbey destroyed after French Revolution
Cluny III, once the largest building in Europe, was little more than rubble when Harvard architectural historian Kenneth Conant laid eyes on it in the 1920s. His efforts to painstakingly recreate the medieval abbey as it looked in the Middle Ages — outlined as part of an exhibition now on view at the Graduate School of Design — illustrate how architects learn to see what isn’t there.
“The exhibit is the story of a man and his passion, which is the Cluny abbey church, and how we can experience it today using modern tools,” said Matt Cook, digital scholarship program manager at Harvard Library, who worked closely with curator and architectural historian Christine Smith. “Several teams across Harvard Library allowed Christine to realize her vision for the exhibit with emerging technology.”
Construction began on the Benedictine abbey of Cluny III, located in the Burgundy region of France, in 1088. It stood for more than 700 years, growing to more than 500 feet long and 100 feet high; at one time, it was home to about 1,000 monks. But after the French Revolution, the impressive structure was demolished and sold for scrap materials.
When Conant first arrived at Cluny decades after its destruction, all that remained was the south transept and eight partially destroyed capitals, or the decorative tops of columns, which once stood behind the altar.
Conant received his undergraduate and graduate degrees from Harvard and taught architectural history at the University from 1920 to 1954. It was an era when architectural historians were still learning to classify medieval architecture and to understand what a building might have looked like in its original form before pieces were added or taken away over the centuries.
Kenneth Conant as a student at Harvard University.
Conant inside an excavation at Cluny III.
“It’s a kind of an idealism,” said Smith, who is the Robert C. and Marian K. Weinberg Professor of Architectural History.
The “idealist” task that Conant gave himself was to imagine Cluny III as it once was, in excruciating detail, based on what he knew of similar buildings and on 20 years of excavations.
Conant tried to identify the original form of the abbey church before later additions were built.
Conant made precise illustrations of the inside of Cluny III from a variety of perspectives, all without ever seeing the building.
“It was unimaginably immense,” Christine Smith said of Cluny III.
Like Conant himself, “Envisioning Cluny” attempts to recreate the feeling of being inside one of medieval Europe’s largest buildings, long since ruined.
“In my own work, when I’m studying something, I try to know it in such reality and detail that I live it,” Smith said. “I think that’s what he’s doing: He’s living it. He wants to see it. He wants to feel it in many different ways. He wants to understand it objectively, but also in terms of the color, the light, how you moved around in it, how it felt to be there.”
Technology allows viewers to interact with architectural designs in ways Conant’s contemporaries could not have imagined.
The enduring mystery of the Cluny capitals
The eight capitals discovered at Cluny III fascinated Conant. They were damaged, with key details missing, but each seemed to feature ornate designs of people, plants, and musical instruments. It wasn’t clear which sides ought to face the front, or what order they should go in, or if they even told a cohesive story.
Some of the Cluny III capitals are theorized to represent the four seasons, the four winds, and the eight modes of music.
It’s possible that sculptors drew inspiration from the columns from the illustrations in contemporary manuscripts.
“Some people think they’re all by one sculptor; other people think they’re by two identifiable sculptors; other people think we don’t know,” Smith said. “There’s a lot of uncertainty about them, which is what’s fun.”
Early in his career, Conant hoped the columns told a single story about the virtues of monastic life, Smith said. But eventually, he came to believe there was little uniting them as an octet. To this day, there are no firm answers, but they remain an object of study as one of the earliest examples of figural sculpture in the Romanesque era.
From plaster casts to 3D
Contemporary students of architectural history don’t have to rely on the stone capitals themselves, or even the unwieldy plaster casts that scholars have traditionally used as aids.
Use your cursor or fingers to manipulate these 3D recreations of Cluny casts.
Using a method called photogrammetry, Harvard Library Imaging Services photographed the plaster casts of the Cluny columns to create the 3D models that are featured in the exhibit. The team took hundreds of individual photos of each capital cast to create each model. Additionally, library conservators, archivists, and curators prepared the print and photo reproductions on display.
Viewers can interact with historic architectural designs up close.
With the 3D scans, Smith and her students can zoom in, rotate, and rearrange the eight capitals and each of their designs in a way previous generations never could, giving them new insight into the enduring puzzle of the octet.
“I can compare them in a way that I can’t with the plaster cast,” Smith said. “I can look at all eight of them in a row.”
It’s a different experience for today’s architectural students than for Conant and his contemporaries, she said. But at the core, the exercise is the same: Learning to see what’s there, and learning to imagine what’s not.
“Envisioning Cluny: Kenneth Conant and Representations of Medieval Architecture, 1872–2025” is on display through April 4 in the Druker Design Gallery.
Photos by Grace DuVal
Campus & Community
Rakesh Khurana shares lessons learned at helm — and as an influencer, off- and online
Melih Cevik ’27
Harvard Correspondent
March 27, 2025
long read
Danoff Dean of Harvard College to step down at end of academic year after 11-year tenure of advances, innovation, and challenges (including pandemic)
For Rakesh Khurana, understanding the mission
Rakesh Khurana shares lessons learned at helm — and as an influencer, off- and online
Melih Cevik ’27
Harvard Correspondent
long read
Danoff Dean of Harvard College to step down at end of academic year after 11-year tenure of advances, innovation, and challenges (including pandemic)
For Rakesh Khurana, understanding the mission comes first. Without it, the what-do-we-do-next-and-how are meaningless.
That principle helped guide Khurana, who will step down at the end of the academic year after 11 years as the Danoff Dean of Harvard College and return to teaching in the Faculty of Arts and Sciences and at Harvard Business School.
Khurana, the Marvin Bower Professor of Leadership Development and a professor of sociology, first arrived at Harvard in 1993 for graduate school, earning a master’s in sociology in 1997 and a Ph.D. in organizational behavior in 1998.
During his tenure as dean, Khurana worked to enhance opportunities in the arts and public service, reorganized office infrastructure to better align supports for students, helped launch the Intellectual Vitality initiative, and defended the goal of recruiting students to the University from a diverse set of backgrounds and experiences.
And, of course, he built a presence on Instagram affectionately known as the Deanstagram. In this edited conversation, Khurana talks about the work he’s done and the lessons he’s learned — about himself and the community.
You’re one of the longest serving deans of Harvard College. Can you talk a bit about aspects of your tenure that you found particularly gratifying?
I think I’ve had the best role in higher education. As an immigrant to this country, growing up in a family that held higher education and education as sacred and Harvard as being one of the institutions that embodied that idea, I feel lucky.
Part of what we accomplished from the start was knowing that we were going to be a mission-oriented organization and institution, going back to the founding. Our aim has been to educate citizen leaders and be clear how we do it — through the transformative experience of a liberal arts and science education and developing specificity around the intellectual, the social, and personal transformation.
One of the things that I feel good about is that there’s a strong sense of understanding of the College’s mission. That clarity has let us take numerous actions on everything ranging from adopting an honor code, which is emblematic of the kind of aspiration that we want to have for our students, to the renewal of the Gen Ed program, which occurred at a time when there was a debate over whether it would even continue.
The commitment to the idea of a general education that’s broad and anchored in the liberal arts and that centers on important questions of society is really critical. Professor Michael Sandel’s renewed class “Justice” is one example of creating a intergenerational connection between our students and alumni who took that class decades earlier that both honors the past, but that’s also relevant/critical for the issues of today.
I am also proud of our work on the Intellectual Vitality initiative, which was something the team had been focused on for several years. Having a data-informed but also flexible approach helped us recognize how Harvard could avoid the fashion of the day and rather commit to substance on these issues. I hope the approach of holding true to our mission and at the same time evolving is remembered as one of the mainstays of my deanship.
“To be in a place where the past is being honored, the present is being contended with, and where the future is being shaped through research is an incredible privilege.”
During your tenure as dean, you faced various challenges. Is there one you think you learned the most from?
Universities reflect the world, but they can also magnify what is happening beyond our campus. Bringing together people who are, for the first time, living with and learning from people with very different backgrounds and experiences is probably the greatest opportunity we have.
But creating this community requires building a lot of capacities and skills and role modeling. Maybe in the past we could take for granted that this all existed, but I think we can’t assume that students and faculty and staff are coming here with this understanding.
We have to recognize that Harvard is not a perfect institution. I think recognizing this work of bringing together people with different backgrounds and experiences has existed in this institution from Day One. This is an institution that recognizes that excellence comes in a variety of forms. In the process of that evolving understanding we get closer to our motto of veritas.
How different was the job of being dean from what you expected?
My background is as an organizational sociologist, and my particular focus is studying institutions, leadership, and bureaucracy. In that field, you learn a lot of theory, do empirical work, write case studies.
There’s a lot of knowing, and then there’s the doing, and then you discover the knowing/doing gap. While some of what you teach are concepts that are helpful and useful, they’re often ideal types that don’t take into account all the particular contingencies and challenges of the specific experiences.
There are three things that, for me, held true. A sense of mission — “What is our purpose?” The vision — “Where are we going?” And the values, or “How are we going to get there?” The power of that is something I’d been teaching about for years, and it’s so interesting to see how powerful it is and how easy it is to forget. I start every meeting with the College mission. If people who are leading are not minding the mission and the vision and the values, who is?
The second lesson that I learned is the microscope that we’re under. When you’re in a position of responsibility, you are constantly role modeling. People are not just paying attention to what you say, but to what you do. Your walk has to be your talk. In fact, your walk is probably more important than your talk.
Something you learn working with students and your team is that you’re a coach, and you’re often trying to figure out what people’s aspirational skills are, what their motivations are. While you’re coaching them to try to help connect those two, in the process you’re coaching yourself.
The other thing I learned is that we’re all works in progress. We’re all trying to become better versions of ourselves. If you’re surrounded by people who care about the mission, who understand the vision of where we’re going, and desire to operate with those values, you can create incredible trust, allowing you to do important things, including getting through some really difficult moments.
Structurally, the most difficult moment was COVID-19.
In many ways we had to live without the things that made us distinctive, the day-to-day being on this campus: the serendipity, the sense of learning to see behind each other’s eyes and hear from each other’s perspectives, not only in the classroom but in the dining halls, in our student organizations. To de-densify campus in a short time period, to try to deal with the reality of the situation, the uncertainty that it presented, and keep academic continuity. Keeping the academic mission going and then restarting and bringing people back to campus in a safe way with the protocols and the testing. That was the most challenging moment, but it was the moment where the University worked as one institution to move forward in a really powerful way.
“Harvard is not a perfect institution. I don’t think we should be a perfect institution because if we were coming close to that ideal, that would mean we are not playing a big enough game.”
You’ve been vocal in warning about the challenge higher education faces with declining trust. How do we rebuild that?
Rebuilding trust is not something that can be done overnight. Part of what we have to do is to make sure that our core is quite strong. The basic functions that people expect of a university around teaching and research must be rock-solid.
For a place like Harvard our legitimacy has depended on two things: a commitment to academic excellence and a commitment to meritocracy.
I would say there are three things that institutions like ours should be doing. One is that we convene excellence — in our faculty, our students, and staff. We should be highlighting excellence in bringing people together.
Second is our commitment to veritas. The reason we depend on academic excellence and meritocracy is that it gets you to a better understanding of the truth. We need to be an institution that lives with an uncomfortable truth rather than a comfortable delusion.
The third thing we need to do is streamline as an institution.
In our commitment to being a place where people across differences and backgrounds and experiences can openly and thoughtfully discuss complex issues, we have two responsibilities.
First, we have to make sure that if we’re asking families to invest in our education, we have to educate effectively.
Then there’s the moral responsibility. Any institution that takes on the responsibility of educating youth is a moral institution at the same time. And this cannot be politicized. When you are politicized, people believe you are producing biased research, not encouraging independent thinking, inculcating ideology, or not allowing for conversations on difficult topics.
Many in the community think one of your defining characteristics is your approachability. Is that something that you’ve always had, or did you develop that over time, and if so how?
It would probably surprise people that during the time I spent in college, I could count on my hands how many times I ate a meal with somebody. I had a small group of friends, but they kept very different hours than I did. They were all artists and painters, and so they would work like night owls. I was in social science and would get up early, go to the library to study.
I ate most of my meals by myself, but I never felt lonely. I had my books. I always felt I was in conversation with scholars like Max Weber, John Stuart Mill, Milton Friedman, and others. It wasn’t that I didn’t like people. I was using the four years I had in college to do something I didn’t think I’d ever have the time to do again — work on my thinking and understanding of the world.
In hindsight, I think I should have realized that I had just as much to learn from my peers. Something I learned from my mother and from Stephanie, my partner, is that everybody has an important and interesting story to tell.
My mother would always say, “Nobody’s better than you, but you’re also not better than anyone else.” That kind of humility is something that I just love my parents for because when I came to graduate school I just found myself being friends with and getting to know everybody — not only my peers, but also the custodial staff and the staff at the sociology department and at HBS. I just started realizing that everybody had such an interesting story to tell.
I would often look for the student who was sitting by themselves at a meal and think to myself, “I wish somebody would have sat with me at that time.” I always found myself drawn to sitting with students, which culminated in us becoming faculty deans at Cabot House. That’s when I became comfortable with being uncomfortable in terms of just sitting with somebody new and asking them a couple of questions, and it has become one of the most joyful parts of my day.
Something that you’ve often spoken about is being an immigrant kid who attended New York City public schools. Did that kid ever think he would be the dean of one of the world’s leading educational institutions?
I was born in India. My parents immigrated to the U.S. the same way millions of other families have for the same reason of trying to build a better life for their kids, and primarily for the educational opportunities.
My mother was a public school teacher in the Bronx, and my dad was an accountant for the city. I always remember that we would move because my mom would look at which schools had higher Regents scores, even a couple of blocks, so that we would be zoned for that school. I know firsthand the transformative power that education has — not just on the individual life, but the generational impact that it has.
My higher education experience began at SUNY Binghamton, and then I transferred to Cornell when a professor came up to me after class and said, “You’re doing well in this class. You should think about transferring to Cornell.” I was like, “Why?” He said, “I went there, and I think you would do really well.”
I had never had a teacher say something like that. It showed the power of a teacher seeing something in you that you didn’t even see yourself. This highlights the power of the mission. How do you create those opportunities for interaction where a conversation, question, or suggestion ends up shaping and changing the trajectory of your life?
After college, I worked in a small tech startup that ended up growing. Somebody from HBS came to write a case study on the company and that conversation led me to apply to graduate school. The next year I was at Harvard.
What does working on this campus mean to you now that you’ve been teaching and leading for so many years?
One of the things I love to do is just go to higher education institutions and visit campuses. I remember the first time seeing the libraries, the first place I would go when visiting. Visiting Cornell’s Sage Hall library, Widener and Baker libraries at Harvard, and dropping off my brothers at Dartmouth and Wesleyan.
To be in a place where the past is being honored, the present is being contended with, and where the future is being shaped through research is an incredible privilege. At times when things can feel challenging, we need to remember that colleges and universities are a candle in the darkness. We have a special responsibility to make sure that that candle is burning bright.
Harvard is not a perfect institution. I don’t think we should be a perfect institution because if we were coming close to that ideal, that would mean we are not playing a big enough game. Our aspirations should always run ahead of our reality.
Final question: Are we going to have to go to Allston to get a selfie?
It will be interesting to highlight the life of a professor, so I plan on continuing my Instagram. I think sharing our experiences on campus helps also with the element of rebuilding trust, because it takes away the mythology that institutions like ours don’t have people who are working hard and trying to do their best for the world. As former President Drew Faust said, “Harvard’s not trying to be the best in the world. It’s trying to be the best for the world.” My sense is that is what the community is, but you can’t tell that. You have to show it.
Nonie K. Lesaux.Niles Singer/Harvard Staff Photographer
Campus & Community
Nonie Lesaux named HGSE dean
Scholar in literacy development and early learning has served as interim dean since July 2024
Nicole Rura
Harvard Correspondent
March 27, 2025
4 min read
Nonie K. Lesaux, the Roy Edward Larsen Professor of Education and Human Development, has been named dean of the Harvard Graduate
Scholar in literacy development and early learning has served as interim dean since July 2024
Nicole Rura
Harvard Correspondent
4 min read
Nonie K. Lesaux, the Roy Edward Larsen Professor of Education and Human Development, has been named dean of the Harvard Graduate School of Education. Lesaux has served as interim dean since July.
“For the past eight months, Nonie has led as interim dean with a wonderful combination of energy and insight,” said Harvard President Alan M. Garber. “Amid unprecedented challenges to both K-12 and higher education, she has demonstrated her ability to meet the moment, bringing to her work courage, humility, and respect in equal measure, motivated always by a deep sense of obligation to the School and its vital mission.”
Lesaux is a developmental psychologist whose career has focused on strategies and innovations to improve learning opportunities and literacy outcomes for children and youth and on leading system-level change in education.
She is currently co-director of the Saul Zaentz Early Education Initiative at the Ed School, which addresses the global challenge of scaling and improving the quality of early education through research, professional development for educational leaders, and graduate training. The Zaentz initiative includes the Early Learning Study at Harvard, a first-of-its-kind statewide study that examines the effects of early education and care settings on children’s learning and development.
“This is a complex time for the education sector, but I can think of no institution better matched to address today’s needs,” Lesaux said. “In the eight months since I assumed the role of interim dean, I have witnessed the ways in which our Ed School community has stepped up to think both critically and collaboratively about our mission and work in service to society. Our collective effort matters more today than perhaps ever.”
A widely respected scholar and educator, Lesaux has written and edited numerous scholarly publications on children’s literacy development and learning. She has also translated ideas from her research into several books for school leaders and educators.
This work has informed how states and districts approach the teaching of reading across the country, including inspiring Massachusetts legislation intended to advance third-grade reading proficiency. Her research was also used to establish a framework for literacy reform in the New York City and Chicago public schools.
Lesaux has served in leadership roles on the national and state level, including as a member of the U.S. Department of Education’s Reading First Advisory Committee and the Institute of Medicine and National Research Council’s Committee on the Science of Children Birth to Age 8.
In addition, she chaired the Massachusetts Board of Early Education and Care from 2015 to 2022, which provided oversight of the state agency that licenses and supports childcare and community-based public programs for young children.
Her previous institutional leadership roles at the Ed School include academic dean and faculty director of doctoral studies.
“I’m delighted that Nonie Lesaux will become dean of the Harvard Graduate School of Education,” said Provost John F. Manning. “She is a collaborative, creative, and inspiring leader, who will lead HGSE with distinction.”
Lesaux joined the Ed School faculty in 2003 as an assistant professor. She earned her Ph.D. at the University of British Columbia and was a postdoctoral research fellow at BC Children’s Hospital. She received her undergraduate degree in psychology, with honors, from Mount Allison University in New Brunswick, Canada.
Lesaux has earned numerous honors, including the William T. Grant Scholars Award and the National Science Foundation’s Presidential Early Career Award for Scientists and Engineers, the highest honor given by the U.S. government to young professionals beginning their independent research careers. In 2019 she was elected to the National Academy of Education.
She serves on the board of the Spencer Foundation and as an expert consultant to the U.S. Department of Justice, Civil Rights Division, Educational Opportunities Section.
Lesaux succeeds Bridget Long, the Saris Professor of Education and Economics at the Ed School and a Harvard University Distinguished Service Professor, who left the post at the end of the last academic year.
Science & Tech
Results from global collaboration raise questions about future of universe
Credit: KPNO/NOIRLab/NSF/AURA/B. Tafreshi
Center for Astrophysics | Harvard & Smithsonian
March 26, 2025
3 min read
CfA astronomers play crucial role in DESI analysis of dark energy, matter
New results from the international Dark Energy Spectroscopic Instrument (DESI) collaboration, which includes res
Results from global collaboration raise questions about future of universe
Credit: KPNO/NOIRLab/NSF/AURA/B. Tafreshi
Center for Astrophysics | Harvard & Smithsonian
3 min read
CfA astronomers play crucial role in DESI analysis of dark energy, matter
New results from the international Dark Energy Spectroscopic Instrument (DESI) collaboration, which includes researchers from Harvard, suggest that dark energy, widely thought to be a “cosmological constant,” might be weakening over time. This suggests the standard model of how the universe works may need an update.
The fate of the universe hinges on the balance between matter and dark energy, which is the force thought to be driving the universe’s accelerating expansion. DESI tracks dark energy’s influence by studying how matter is spread across the universe. The new analysis, using the largest 3D map of our universe ever made, looked at dark energy’s influence over the past 11 billion years.
The results, using the first three years of collected DESI data, were announced in a March 19 press release from the Lawrence Berkeley National Laboratory.
Events in the very early universe left subtle patterns in how matter is distributed, a feature called Baryon Acoustic Oscillations. That pattern acts as a standard ruler, with its size at different times directly affected by how the universe is expanding. Measuring the ruler at different distances shows researchers the strength of dark energy throughout history.
Combining the data of more than 14 million galaxies and quasars with the results from other experiments, scientists have stronger evidence that the impact of dark energy may be evolving in unexpected ways.
The Center for Astrophysics | Harvard & Smithsonian (CfA) researchers, led by Harvard Professor Daniel Eisenstein and his group, were crucial contributors to the DESI collaboration in multiple ways, including co-developing algorithms and simulations that led to the latest results.
Cristhian Garcia Quintero is one of the collaboration leads on the cosmological interpretations of the results. Michael Rashkovetskyi performed calculations that are critical for the distance measurements. Claire Lamman is the co-chair of the DESI education and public outreach committee and helped create the visual material for the public. Eisenstein served as co-spokesperson of the collaboration from 2014 to 2020.
DESI involves more than 900 researchers from over 70 institutions around the world and is managed by the U.S. Department of Energy’s Berkeley Lab. The collaboration shared its findings in multiple papers to be posted on the online repository arXiv and in a presentation at the American Physical Society’s Global Physics Summit in Anaheim, California.
Alongside unveiling its latest dark energy results at the summit, the DESI collaboration also announced that its Data Release 1 is now available for anyone to explore. With detailed information on many millions of celestial objects, the data set will support a wide range of astrophysical research at CfA and elsewhere.
In addition to contributing to DESI’s cosmology goals, CfA researchers are using the collaboration to study galaxy evolution, the cosmic web, and the structure of the Milky Way. The DESI survey continues each clear night, extending its map of the cosmos and giving astronomers a continually improving view of the physics of the Universe.
DESI is supported by the Department of Energy’s Office of Science and by the National Energy Research Scientific Computing Center, a DOE Office of Science national user facility.
Nation & World
Declassified JFK files provide ‘enhanced clarity’ on CIA actions, historian says
Declassified documents related to the President John F. Kennedy assassination were released on March 18. George Walker IV/AP Photo
Christina Pazzanese
Harvard Staff Writer
March 26, 2025
6 min read
Fredrik Logevall, Pulitzer winner writing three-volume Kennedy biography, shares takeaways from declas
Declassified JFK files provide ‘enhanced clarity’ on CIA actions, historian says
Declassified documents related to the President John F. Kennedy assassination were released on March 18.
George Walker IV/AP Photo
Christina Pazzanese
Harvard Staff Writer
6 min read
Fredrik Logevall, Pulitzer winner writing three-volume Kennedy biography, shares takeaways from declassified docs
Six decades later, Americans know a bit more about the CIA’s clandestine operations in the early 1960s, particularly in Cuba and Mexico, thanks to a new tranche of declassified documents concerning the assassination of President John F. Kennedy released last week.
The more than 77,000 pages released by the National Archives and Records Administration do not appear to contradict the Warren Commission’s conclusion that gunman Lee Harvey Oswald acted alone when he shot Kennedy in Dallas on Nov. 22, 1963. But historians say the papers hold important new details about the CIA’s involvement in foreign elections during the Cold War and its infiltration of Fidel Castro’s inner circle.
In this edited conversation with the Gazette, Fredrik Logevall, a professor of history and the Kennedy School’s Laurence D. Belfer Professor of International Affairs, highlights key details in the documents, shares what he’d still like to know, and offers some thoughts on why the assassination of JFK remains fodder for conspiracy theorists. A Pulitzer Prize-winning author, Logevall published the first book in a three-volume series on Kennedy in 2020. The second volume will be published next year.
What’s your impression of this new tranche of JFK records? Have you seen anything noteworthy so far?
With respect to the assassination, there’s little or nothing that’s new, at least in terms of what I’ve been able to see thus far. I can’t say I’m surprised — going in I didn’t expect we’d learn anything that would overturn our understanding of what happened in Dallas. The releases are, however, quite interesting on U.S. covert operations in the Cold War in the early 1960s. Some of them range beyond Kennedy’s years, but it’s for this period that they’re most interesting, especially with respect to Latin America. That’s actually been quite revealing to me.
“Interesting” in terms of what the CIA was doing or the volume of things they were doing back then?
In a way, it’s both. A lot of the “new” documents had been released before; the difference now is that they are unredacted. In 2017, for example, we got some really important CIA documents, but they would have certain words or passages blocked out. What’s been illuminating for me, even though it’s sometimes just a handful of words, is to have those words inserted. This matters, because as we know even a few words can change the meaning of a sentence or a passage dramatically. What we see with enhanced clarity is just how involved the United States was in other countries, not least in interfering in elections. In the past, country names or the names of leaders would have been omitted. Now they are there in black and white. There’s just something about seeing it say “Brazil” or “the Finnish elections,” for example, that makes this more clear, more stark. Also, you see just how large the presence of the CIA was. In certain embassies, those who are attached to the CIA could make up almost half the total personnel. Even those of us who are historians of the Cold War were somewhat taken aback by these figures. If you had asked me a week ago, I would have said that in this or that key embassy, there’s probably 20 percent max secretly attached to the CIA. I had no idea that it was sometimes approaching 40 or 50 percent.
Fredrik Logevall.
Photo by Peter Hessler
Did we learn more about why Kennedy had a fraught relationship with the CIA?
We have not, though this could be buried in there and I just haven’t seen it yet. I thought we might learn more about that important relationship. You’re right to say that there was a wariness between JFK and the agency for various reasons. Some authors have exaggerated the depth and width of the schism, but it was there.
What’s something notable that you discovered?
In one CIA document, dated April 24, 1963, we learn that 14 Cuban diplomats were our agents. That’s quite significant — the degree to which there were people inside the Cuban government who were, in fact, working for the agency. In terms of the so-called Operation Mongoose, which was the effort to destabilize and overthrow the Cuban government, this helps us better understand to what extent were Cubans assisting in that effort. Later in the same document, we learn that there were two Cuban ambassadors on the payroll who provided first-rate reports and were closest to the bone in what Castro was thinking.
What are some key questions historians still have about the Kennedy assassination? Is there much left to learn?
I would like to know more about Oswald’s movements before Dallas. I would like to know more about his visit to Mexico City, which was in late September-early October 1963, just a few weeks before the assassination. He was flirting with defecting to Cuba, and so, in Mexico City, he met with both Cuban diplomats and Soviet diplomats. What exactly was said in those conversations? I’m interested, more broadly, in what U.S. intelligence agencies knew and didn’t know about his whereabouts in these weeks. That’s maybe the biggest issue for me.
The JFK assassination is often cited as the progenitor of modern conspiracy theory culture. Why is there still so much suspicion around it?
Part of it is simply because a president was killed, a president seemingly in the prime of life. I think we human beings have a natural inclination to believe that great events must have great causes. It seems somehow impossible that it was a lone misfit named Lee Oswald who took it upon himself to shoot the president. There’s got to be more to it than that, we tell ourselves. And so, the conspiracies will continue to fly. Regardless of what these documents would or would not have revealed, it would not have satisfied people who believe others were involved.
Someone asked me why we don’t seem to have the same consuming interest in, say, Lincoln’s or RFK’s assassination. It might have something to do with a few things. First there’s the fact that Oswald himself was killed two days later. Understandably, this makes people say, “How was that allowed to happen?” Second, the Warren Commission, which was a government commission formed to investigate the murder, was serious and thorough, but it made mistakes, notably in neglecting to interview everyone it might. Third, the fact that the assassination was captured on film might make a difference. So many of us have seen the Zapruder film, and it lives on in our mind, makes the whole thing more real, more eternal. Finally, there’s the oft-heard suggestion — the implications of which I’m still trying to sort out myself — that something important was lost on that day in Dallas, that it marked the end of American innocence somehow.
Put all of that together, maybe you have part of the explanation for why this particular event has been such fodder for conspiracy theories.
Andrea Baccarelli.
Campus & Community
A year into role, Chan School dean focused on driving change amid deep challenges
Andrea Baccarelli has laid out a vision for expanding the School’s impact while navigating a rapidly shifting landscape for federally funded research
March 26, 2025
9 min read
Andrea Baccarelli has been managing change since he started as dean of Harvard T.H. Chan School of Public H
A year into role, Chan School dean focused on driving change amid deep challenges
Andrea Baccarelli has laid out a vision for expanding the School’s impact while navigating a rapidly shifting landscape for federally funded research
9 min read
Andrea Baccarelli has been managing change since he started as dean of Harvard T.H. Chan School of Public Health in January 2024.
On his very first day, Baccarelli entered an environment where the war in Gaza exerted pressures across campus. More recently, rapid shifts in federal policies have raised immediate implications for the Chan School. With about 60 percent of its revenue coming from research grants, primarily from the federal government, the School would face a significant blow to its budget if deep cuts proposed by the National Institutes of Health and other agencies were implemented. Baccarelli has convened a financial planning group of senior leadership, including academic department chairs, to plan for the potential effects.
Amid these challenges, Baccarelli has been developing plans to expand Harvard Chan School’s reach by nurturing high-quality, interdisciplinary, solutions-focused science. In this edited conversation with the Gazette, Baccarelli discusses this vision and his approach to current funding uncertainties.
You recently introduced your “AAA Vision” for Harvard Chan School. What does it look like?
Our work is all about saving lives through the highest quality science. That hasn’t changed since our School was founded 112 years ago. We have an exceptional track record. For instance, scientists at our School created a low-cost, easy-to-ship rehydration solution that has saved more than 25 million children from death due to diarrheal disease. They engineered infertile mosquitos to eradicate malaria and are developing new therapies to treat diabetes. Rooted in this record of excellence, the AAA Vision is a strategic path to expanding our impact still further. The three As, which grew out of my listening tour, stand for agile, accessible, and accountable.
Agility is all about being able to pivot quickly to respond to new opportunities. As a School, we must be more entrepreneurial. That will require forging collaborations — inside and outside of Harvard — with all sorts of people who are not traditional partners for public health, like engineers and industry CEOs. The way I see it, we all share an interest in developing solutions to problems with immense human and economic costs, like rising rates of Alzheimer’s disease and the spread of multi-drug-resistant infections. Public health is all about taking on these challenges, and we stand ready to work with anyone who can help.
The second A, accessibility, relates to both education and research. I hope to significantly expand our educational offerings by creating more short courses and certificate programs and by delivering more content online. There’s a tremendous need for public health knowledge in just about every profession, and Harvard Chan School has the potential to be a hub for people who want to expand their skills at any stage of their careers.
On the research front, we need to keep working to get our findings in front of pharma executives, biotech investors, entrepreneurs, policymakers, the public, and potential collaborators — to make our science accessible. After all, our goal is not just to advance knowledge in the abstract, but to develop solutions that will make a real difference in people’s lives.
The final A is for accountable. We must be accountable to our mission, delivering the very best education and conducting the highest-impact research to improve health for all communities. We must also be accountable to our values. Public health starts at home, and I am committed to building a pluralistic and inclusive community where everyone feels welcomed and valued.
The uncertainties driven by shifts in federal policy are especially acute at Harvard Chan School, which relies heavily on federal grants. What impacts are you seeing at this point?
Unfortunately, we have had more than a dozen federal grants terminated so far because they do not align with new priorities at the National Institutes of Health and other agencies. Those terminations have abruptly cut off important research.
Like the rest of the University, we are also closely monitoring the proposed NIH cut to facilities and administration funding. F&A funding is often called “indirect” funding, but there’s nothing indirect about it. It truly is essential funding for research. A cut of the size the NIH has proposed — to a flat rate of 15 percent — would be devastating. It would have huge impacts on our ability to do critical research in fields like preventing cancer, slowing neurodegeneration, and identifying dietary factors that contribute to longevity.
As dean, how are you considering addressing this gap in federal funding to support research at the School? Can philanthropy make up the difference?
Philanthropy plays a very important role in supporting our research and education mission, but it’s unrealistic to imagine it could make up for our long-standing partnership with the federal government. That said, we are working hard to connect with potential donors to explain why our work matters. In fact, I just got back from a trip to Europe where I talked to supporters in several countries. The top message I shared was that our research has tangible impacts in the real world, helping to shape policies and programs that keep us healthy. And donors can make that research happen.
As one example, private philanthropy just funded a 10-year study of the health impacts of wildfires. This is groundbreaking work: A multi-institutional team led by Harvard Chan researchers is assessing all the pollutants that people living near the Los Angeles wildfires have been exposed to, mapping how these toxins spread or dissipate over time, and tracking the short- and long-term health effects. It’s an incredibly important study, made possible entirely by a generous donor who loves L.A. and wants to protect the public’s health. I hope to encourage more such partnerships with philanthropists who are aligned with our mission of using science to build a world where everyone can thrive.
Returning to the AAA Vision: Can you share a bit more about how you’re approaching accountability and what that looks like with respect to the mission?
Yes, In fact, it’s fundamental to what we do at the Harvard Chan School.
We must put in place processes that ensure that our School’s courses and degree programs consistently offer the highest level of excellence. As a starting point, I recently appointed a faculty working group to review processes and criteria for appointing and renewing instructors. At Harvard Chan School, instructors are non-ladder appointees who play a crucial role in classroom teaching. I tasked this working group to ensure rigor and consistency in how our instructors are appointed and renewed and ensure they have the excellent academic credentials and specific expertise they need to teach classes with the depth and rigor our students deserve. We will then go through a similar process for each tier of academic appointment at Harvard Chan School — lecturers, research scientists, adjuncts, etc. To complement this initiative, I also plan to strengthen our internal review processes for courses and degree programs to ensure they consistently meet the highest academic standards.
To a similar end, I have also relaunched periodic reviews of our centers and programs to ensure the highest quality of scholarship and teaching excellence. For instance, late last summer we initiated a comprehensive review of our FXB Center for Health and Human Rights. We have appointed a blue-ribbon panel of experts to conduct this review, which will conclude this spring. The charge to the review panel is to rigorously evaluate the FXB Center’s current status and future potential, offering candid, forthright, and thorough feedback, including any shortcomings or areas of concern, to ensure the Center meets — and is held to — the highest standards of excellence expected of a University-wide center at Harvard. While this review is ongoing, we have halted the formal collaboration between the FXB Center and Birzeit University. This allows the panel to objectively evaluate partnerships and collaborations and ensure the center exemplifies academic excellence in alignment with our mission. We will conduct similar periodic reviews of all our centers and programs.
I’m also putting a lot of focus on building a pluralistic culture that is accountable to our values. From my earliest messages to the community, I have tried to make clear that all of us can expect to be exposed to speech that we disagree with, even speech that offends us, during our time at Harvard. That’s to be expected at any university with a commitment to free speech and academic freedom. Of course, I have zero tolerance for any speech or conduct that constitutes discrimination or harassment — such behavior is wholly unacceptable and will be addressed decisively at our School. But I’ve emphasized how important it is to be open to learning from people with different views — and how important it is to be able to communicate respectfully and with integrity.
To build those skills, my team and I launched an initiative called Harvard Chan LEADs, which stands for Learn and Engage Across Differences. We created a new module for orientation to engage students in these values as soon as they arrive on campus. Since then, we have hosted quite a few workshops and events, including special trainings to help faculty foster respectful conversations in the classroom, even when the topics are divisive.
I’m also launching the Harvard Chan Citizenship Awards. This award will be given each year to three people — a student, a staff member, and an academic appointee — who best represent our values and who have done the most to create a culture of pluralism and inclusivity. It’s all part of making sure we are accountable to our mission, our values, and one another.
What are some of the key ways you’re mobilizing around the other two As, agile and accessible?
We have taken some promising steps toward making both our education and our research more accessible. On the education front, I set up a working group to assess opportunities for expanding our non-degree offerings. On the research front, our Center for Health Communication has launched an innovative project to connect our faculty to social media creators, with the goal of expanding the amount of scientific content on platforms like TikTok.
In terms of agility, I’m very excited to be collaborating with Harvard Business School, Harvard Medical School, and Harvard John A. Paulson School of Engineering and Applied Sciences on a research project that models the kind of interdisciplinary problem-solving I’d like to see more of. Our goal is to develop new models for prioritizing and incentivizing preventive healthcare in the U.S. We could save a lot of money and prevent a lot of suffering with a shift to prevention, so this is a project with immense potential.
An exhibition at the Harvard Art Museums asks what we can learn from Edvard Munch’s 40-year obsession with a man and woman at the shore.
Two figures, a man and a woman, stand at a shoreline. They face away from the viewer and toward the sea, side by side and yet isolated from one another.
Sometimes the woman is on the left. Sometimes she’s on the right. Sometimes these figures, and the rocky shore around them, are rendered in careful brushstrokes; other times, perhaps there is a sense of urgency, of haste, of canvas left untouched.
This is “Two Human Beings (The Lonely Ones,)” one of the most famous motifs by the Norwegian painter and printmaker Edvard Munch (1863-1944.) Munch returned to this motif again and again over more than 40 years, in paintings, metal-plate etchings, and a series of woodcut prints, each with slight differences in color, shape, or technique.
“He couldn’t let go,” said Elizabeth M. Rudy, Carl A. Weyerhaeuser Curator of Prints at the Harvard Art Museums and the co-curator of the exhibition “Edvard Munch: Technically Speaking,” on view through July 27. “There are so many more iterations of [‘Two Human Beings’] … in black and white, in grayscale, all violet, monochromatic but in different color schemes, totally different color combinations. There was one we saw in neon color, and the whole thing became psychedelic. With the intensity of variations, the motif starts to have less and less singularity and it can be a vehicle, an exploration of pretty much anything under the sun.”
Munch’s repeated returns to the motif demonstrate the way his paintings informed his prints, and vice versa. He first painted it in 1892, but the painting was destroyed in 1901 in an explosion onboard a ship that was transporting his works for exhibition. When he next painted the motif in about 1906-1908 (above left), he had already experimented with woodblock prints of the theme. The figures appear in reverse from the original painting and were thus likely based on the printed versions, which he would have had as a ready reference.
“He’s mixing a huge range of different painting techniques,” said Lynette Roth, Daimler Curator of the Busch-Reisinger Museum, co-curator of the exhibition. Munch left some of the canvas unpainted; in some places, he applied paint thickly or scratched color away. It’s more than a demonstration of versatility, Roth said: “It also creates a kind of vibration, a sensation of these figures, a dynamism in the painting itself.”
The final version, made in about 1935 (above right), appears more spontaneous than its predecessor, with exposed lines from Munch’s preparatory sketch, large swatches of color, and areas of exposed canvas.
“It was something we were hoping to highlight,” Roth said. “Why this return? What is he learning over time and through the different techniques?”
In his prints, Munch exploded “Two Human Beings” and put it back together again. He used a jigsaw method, inscribing his design onto a block of wood and using a fretsaw to cut each element into its own piece. Then, he could ink each piece separately, push them back together, and run the reunited composition through the press, creating endless variations of color.
Munch incorporated the male figure into the landscape but cut the woman into her own solitary block.
“She almost feels like a doll,” Roth said. “You can take her out, as opposed to the man, who becomes a part of the printing of the landscape. In many of the prints, he begins to feel like he’s more a part of the landscape, whereas she is able to be this very singular figure and a very important one for Munch.”
“He embraced the non-perfect alignment, the break in the block that would be seen then in later prints, the fact that in the painting, things are dripping, things are imperfect. That was something he emphasized: That the too-perfect finish was actually the enemy of the good in a work of art.”
Lynette Roth
“Two Human Beings (The Lonely Ones)” has long been understood as a rumination on isolation, on the sense of loneliness that one can feel even in the company of someone else. But after spending time with Munch’s multiple iterations on the motif, Roth said she’s not so sure that’s the only interpretation.
A savvy businessman, Munch originally titled the work simply “Two Human Beings.” But when others ascribed loneliness to the figures, Munch leaned into it.
“The more I engaged with this, I started to feel like they actually aren’t that lonely,” Roth said. “They’re connected to the landscape; they’re connected also to each other in the way that color unites them, and the way he’s inching toward her. … For me, it’s also companionship and contemplation, which doesn’t have to be devastating or alienating or cause for anxiety.”
A question of finishMunch’s contemporaries sometimes critiqued a lack of polish in his pieces. But Munch embraced the flaws, imperfections, and empty spaces in his work.
In the final painted version of “Two Human Beings,” Munch leaves exposed sketch lines and areas of bare canvas on the woman’s dress.
“Inger in a Red Dress” is composed on board, a cheap support that artists often use when creating studies. But the painting is a fully realized portrait.
Munch has long been understood as a deeply troubled artist whose struggles with mental health are apparent in psychologically evocative works like “The Scream.” But “Edvard Munch: Technically Speaking” invites viewers to disentangle Munch’s artwork from his biography and to view his recurring motifs not only as a window into his psyche but as another material, like paint or charcoal, a vehicle through which Munch explored his artistic practice.
“We know that people will react emotionally or psychologically to what’s on view,” said Peter Murphy, Stefan Engelhorn Curatorial Fellow in the Busch-Reisinger Museum and co-curator of the exhibition. “Two things can be true: Munch did suffer psychologically; although he was wealthy and well-off, he did have a lot of crises in his life. And he was also a mastermind of getting his work out there and exploring it.”
Edvard Munch
(1863-1944)
Norwegian artist Edvard Munch was one of the most significant artists of the Modernist movement, and an innovator in printmaking, painting, and other arts. He is best known for his painting “The Scream,” which is seen as an expression of modern spiritual angst. He was active for more than 60 years, from the 1880s until his death.
“Edvard Munch: Technically Speaking” is on display through July 27 in the Special Exhibitions Gallery on Level 3 at the Harvard Art Museums. The exhibition showcases 70 works, primarily from the Harvard Art Museums collection. Thanks to a transformative gift from Philip A. and Lynn G. Straus, the museums now house one of the largest and most significant collections of artwork by Munch in the U.S.
The new initiative will be housed at Harvard Kennedy School.Harvard file photo
Campus & Community
Harvard launches pilot initiative to tackle some of today’s biggest challenges
Harvard Impact Labs will provide funding and support for faculty to conduct solutions-focused research and drive real-world impact
Harvard Kennedy School Communications
March 26, 2025
5 min read
Harvard announced Wednesd
Harvard launches pilot initiative to tackle some of today’s biggest challenges
Harvard Impact Labs will provide funding and support for faculty to conduct solutions-focused research and drive real-world impact
Harvard Kennedy School Communications
5 min read
Harvard announced Wednesday the launch of a pilot for a new University-wide initiative called Harvard Impact Labs. The initiative will support faculty working in collaboration with leaders in government, nonprofits, and the private sector to develop solutions to pressing societal problems.
Universities have long led the way in generating scientific knowledge to improve the human condition through research in the life sciences and engineering. Harvard Impact Labs seeks to support the impact-focused work of social scientists, harnessing the tools of scientific research to help public leaders solve the problems they confront every day. Each lab will focus on a specific societal challenge, such as local economic development, affordable housing, educational achievement, high-quality healthcare, or public safety.
During the pilot phase, the initiative will have three core components: (1) a fellowship program to support faculty as they develop meaningful scientific collaborations with leaders in the public and social sectors, (2) start-up funding to support these types of collaborations as they design, test, and scale solutions in real-world settings, and (3) public service leaves to give faculty the opportunity to embed in governments or nonprofits to learn more deeply about the problems they wish to work on. Through these functions, Harvard Impact Labs will support faculty who are already doing this critical work and provide others with the skills and resources they need to put their research and expertise to work for society.
“Just as Harvard faculty in the life sciences have long worked to develop medical cures that save and improve lives, Harvard Impact Labs will help faculty and students in other disciplines address the real-world challenges that our society faces,” said Hopi Hoekstra, the Edgerley Family Dean of the Faculty of Arts and Sciences, the C.Y. Chan Professor of Arts and Sciences, and the Xiaomeng Tong and Yu Chen Professor of Life Sciences.
“In this moment of dissatisfaction with the status quo, declining faith in expertise, and skepticism of government and democracy, there has never been a more important time for an initiative like this,” said Jeremy Weinstein, dean of Harvard Kennedy School and Don K. Price Professor of Public Policy. “By giving faculty and students the support they need — and connecting them with real-world practitioners — Harvard Impact Labs can help tackle our biggest challenges and improve lives across the world.”
“Harvard Impact Labs builds on the extraordinary work being done by many of our faculty in partnership with communities across the nation and around the globe, whether improving education, healthcare, housing, public safety, the environment, or a host of other issues,” said Nonie K. Lesaux, the interim dean of the Harvard Graduate School of Education and the Roy E. Larsen Professor of Education and Human Development. “Communities and leaders are working hard to develop solutions, and we can help accelerate more of that work.”
“We are eager to enable more Harvard faculty to work with public- and private-sector changemakers to develop, test, and scale solutions to a range of social problems,” said Jeffrey Liebman, the Robert W. Scrivner Professor of Public Policy at the Kennedy School and co-faculty director of Harvard Impact Labs. “At the Government Performance Lab, I’ve seen firsthand how faculty and students can simultaneously change lives and advance scientific understanding by working directly with those on the front lines of society’s biggest challenges — and I’m thrilled to be building upon that mission with Harvard Impact Labs.”
“Many Harvard faculty are eager to put their expertise to work making a difference outside of Harvard, but it can be hard to know where to start,” said Danielle Allen, the James Bryant Conant University Professor, co-faculty director of this initiative, and director of the Allen Lab for Democracy Renovation. “This initiative is going to make it possible for more faculty to have impact at scale and lead to more rapid progress on some of the nation’s and the world’s most difficult social problems.”
Faculty at all Harvard Schools will be eligible for funding and support. The initiative will be housed at Harvard Kennedy School and report to the deans of the Kennedy School, the Faculty of Arts and Sciences, and the Graduate School of Education. It will be guided by a distinguished group of faculty advisers from across the University and led by co-faculty directors Danielle Allen; Jeffrey Liebman; James S. Kim, professor of education; and Amanda Pallais, the Robert C. Waggoner Professor of Economics. Its executive director, Pauline Abernathy, brings a wealth of experience creating reform at the national, state and local levels while in senior positions in government, nonprofits, and philanthropy. She is a graduate of the Kennedy School’s Master in Public Policy program.
This pilot is made possible by a generous donation from Julian Baker, who graduated from Harvard College in 1988 with an A.B. in social studies.
More information on the initiative can be found on the Harvard Impact Labs website.
Michael Brenner (from left), Matthew Kopec, and Sean Kelly discuss generative AI.Veasey Conway/Harvard Staff Photographer
Campus & Community
Panelists look at challenges, opportunities of GAI tools
New initiative advances conversations about role of AI
Nikki Rojas
Harvard Staff Writer
March 26, 2025
3 min read
When asked if it’s appropriate to use generative AI to grade student papers
Panelists look at challenges, opportunities of GAI tools
New initiative advances conversations about role of AI
Nikki Rojas
Harvard Staff Writer
3 min read
When asked if it’s appropriate to use generative AI to grade student papers, write letters of recommendation, or screen job applicants the audience couldn’t come to a consensus.
First up: Matthew Kopec, program director and lecturer for Embedded EthiCS, who opined, “Science is less fun because of all these tools.”
Quick to push back were Gary King, Albert J. Weatherhead III University Professor, and Michael Brenner, Michael F. Cronin Professor of Applied Mathematics and Applied Physics at SEAS.
“We’re in the business of making discoveries to improve the world for humans,” Brenner said. “We should use every tool that we have at our disposal to do that.” He and King posited that while GAI may make certain scientific endeavors easier, it can also encourage researchers to work on harder problems.
King, who is also the director of the Institute for Quantitative Social Science, noted that Harvard has long taught its students the latest technology to address problems faster and more easily, and GAI is no different.
“The first mathematics books had long passages trying to explain how to do mathematical calculations without wasting valuable paper. Most of us now spend a lot of time trying to figure out how to do calculations without blowing up our computers,” he said. “You should be the kind of person that uses whatever the best tools are to progress the fastest and go the farthest.”
The hourlong panel was the first installment in the spring GAI Dialogues series, part of a wider initiative exploring the impact generative AI has on the FAS educational mission. The initiative, a priority of Edgerley Family Dean of the Faculty of Arts and Sciences Hopi Hoekstra, is being led by her senior adviser on artificial intelligence, Chris Stubbs, the Samuel C. Moncher Professor of Physics and of Astronomy.
The conversation also examined concerns with ethical issues. Despite being an enthusiastic proponent for the use of GAI in science and math fields, Brenner acknowledged the need for scrutiny over who can or should control GAI tools.
King was blunter. “Yes, this technology can be used for harm. Any technology can be used for that. The causal factor isn’t the technology, it’s the humans that decided to use it,” he said.
A question from an audience member on AI’s potential environmental impact had all the panelists agreeing that the technology heavily consumes energy. King answered that AI may ruin the environment, or incent faster creation of new industries to generate clean energy.
“Before you single-handedly eliminate these incredibly visible tools, let’s just figure out the cost and benefits,” he said.
Upcoming events in this spring’s GAI Dialogues include “Teaching With Integrity in the Age of AI” with the College’s offices of Undergraduate Education and Academic Integrity at the Smith Campus Center on Monday. The faculty workshop will explore best practices for using AI in the classroom, potential coursework violations, and prevention strategies. Other events will focus on critical reading and writing in the age of AI, on April 3 and 24, respectively, and “Preparing Students for the Future: AI Literacy in the Liberal Arts” on May 5.
Science & Tech
From Capasso lab to your living room
Image courtesy of Metalenz
Alvin Powell
Harvard Staff Writer
March 25, 2025
6 min read
Rob Devlin helped develop innovative mini-lens as grad student. Now the startup he runs produces millions of them for consumer electronics.
Over the course of his Harvard doctoral studies, Rob Devlin must have made 100 of a new kind of mini-lens,
Rob Devlin helped develop innovative mini-lens as grad student. Now the startup he runs produces millions of them for consumer electronics.
Over the course of his Harvard doctoral studies, Rob Devlin must have made 100 of a new kind of mini-lens, experimenting with materials and prototyping new designs to bend light like a traditional camera only using a series of tiny pillars on a millimeter-thin wafer.
This new device would be smaller, cheaper, and able to be mass produced — if demand ever warranted it — in semiconductor chip foundries.
Today, demand warrants it.
Metalenz, a startup founded in 2016 with exclusive rights to commercialize the device Devlin helped develop in the lab of Federico Capasso, the Robert L. Wallace Professor of Applied Physics, says some 100 million of its light-focusing metasurfaces have been made and are installed in an array of consumer electronic devices.
Metalenz — with Devlin now as CEO — wouldn’t disclose which companies are using its devices in their products, but at least one report from a company that does teardowns of consumer products, Yole Group, says metasurfaces are in the iPad, Samsung Galaxy S23 Ultra, and Google’s Pixel 8 Pro.
“It’s remarkable to think that something that started at Harvard — during my Ph.D. and with the work of all the other folks in the Capasso lab — is now out there and people are using it,” Devlin said. “There are many examples of university technology that have great promise, and having metasurfaces actually end up in real-world devices at the scale that we’re now talking about definitely has a great feel to it.”
Sam Liss, executive director of strategic partnerships at Harvard’s Office of Technology Development, said Metalenz emerged from a group that was cross-disciplinary, leveraging different scientific backgrounds and perspectives into a product that is breaking new ground.
“[Former University President] Drew Faust once said that companies create new products; university research creates new industries.”
Sam Liss, Harvard Office of Technology Development
“It’s really taking conventional optics, which have been around for a very, very long time, and disrupting that industry,” Liss said. “That’s what I think university startups are really great at: true disruption. [Former University President] Drew Faust once said that companies create new products; university research creates new industries. And that always resonated with me.”
Capasso’s early work on metasurfaces began in 2007 or 2008. By 2012, when Devlin arrived at the lab, the science was mostly figured out. In a 2011 paper in the journal Science, which has garnered more than 10,000 citations, Capasso and members of his lab showed they could tune nanostructures on the metasurface to control light at will.
Shortly after, they demonstrated the first metalens, which was able to focus light — albeit inefficiently — on a single spot. From there, Devlin added his expertise in materials and nanofabrication, working with other members of the lab to refine the product. And Capasso set the bar even higher: He wanted not only a product that worked, but one that could be mass-produced using existing fabrication methods so they could go to market quickly.
“In record time, metalenses went from a research prototype in 2016 to the creation of Metalenz in the same year and mass manufacturing for the consumer market in the following years,” Capasso said. “Kudos to Rob Devlin for successfully leading this transition.”
All along, researchers knew the device had the potential to disrupt the traditional business of making lenses from curved pieces of polished glass or plastic. As manufacturers crammed more and more features into smartphones, tablets, and other devices, it became clear that the real estate taken up by bulky lenses was a bottleneck to more advanced designs.
A major early victory for Metalenz came in 2021, when the startup signed a contract with STMicroelectronics to put its metasurfaces into STMicro’s FlightSense module.
The distance-measuring module uses near-infrared light for 3D sensing, and the metasurface is involved in both emitting light and in detecting its reflections. The time taken for the infrared light to bounce back provides key data in drawing the 3D picture. It is used in facial recognition, 3D room mapping, augmented reality, and similar applications.
Though these metasurfaces are not typically used for visual images, they can provide depth information that helps focus visual camera lenses.
Rob Devlin.
Photo courtesy of Metalenz
Metalenz is currently based in Boston’s North End and has doubled in size to about 45 employees over the last three years. The company doesn’t need all that much space, because the manufacturing is left to large semiconductor foundries, which turn out more than a trillion chips a year for the global technology industry.
At Metalenz, Devlin said, the staff focuses on improving performance of their current product and developing what they hope will be the next big breakthrough: Polar ID.
Polar ID uses polarization of light to provide an additional layer of security for smartphones with a dramatic reduction in cost and size.
Devlin said that a traditional polarization camera is about 100 millimeters long and costs $500 to $1,000. Smaller versions have been created but are found only on top-end devices. Metalenz’s polarization metasurface is about 5 millimeters long and costs roughly $5, Devlin said, which would allow their deployment at low cost in many more devices.
“I can get a standard image of you. I can recognize the distance between your eyes and how far your eyes are from your nose and all of these key landmarks,” Devlin said. “But the polarization signature of you is unique, meaning that even if someone came with a perfect 3D mask of you and put it in front of the device, the polarization signature of that 3D mask would be different than your polarization signature.”
Polarization can be used in other applications as well. For example, skin cancer’s polarization signature is different from healthy skin, so it can be used to detect dangerous growths. It can also be used to monitor air quality.
“There are a lot of exciting things stemming from the power of the metasurface to take complex modules, shrink them down, and let you do entirely new things,” Devlin said.
As with any successful product, other companies are working to catch up, Devlin said. Metalenz’s strategy is to continue to improve current products and develop new ones that leverage the technology to do new and interesting things.
He also counted among advantages their continued relationship with Capasso — a Metalenz founder — providing a pipeline to new developments from his lab.
“There’s a lot of competition and folks are trying to catch up to us,” Devlin said. “The benefit we have is really the first applications we’ve already deployed, and we’ve already started to move on to something where we’re using even more of the unique aspects of the metasurface.”
Ugne Klibaite (left) and Bence P. Ölveczky.Photos by Grace DuVal
Science & Tech
How rat watching can yield benefits for people
New AI method lets researchers get better handle on brain-behavior link, may offer insights into disorders like autism
Clea Simon
Harvard Correspondent
March 25, 2025
5 min read
It’s all about the body language.
A new AI method for tracking the social lives
New AI method lets researchers get better handle on brain-behavior link, may offer insights into disorders like autism
Clea Simon
Harvard Correspondent
5 min read
It’s all about the body language.
A new AI method for tracking the social lives of rats may help researchers better understand the relationship between the brain and social behavior, with possible implications for human conditions such as autism.
The machine-learning technique was detailed in a paper, “Mapping the Landscape of Social Behavior,” recently published in Cell. Bence P. Ölveczky, professor of organismic and evolutionary biology (OEB) and co-author of the paper, explained: “We are really mapping the social life of rats by capturing the details of their every movement. We see how they interact with each other, and we see the same forms of engagement over and over again.
“We see personalities in these animals that are intriguing. In many ways, these variations can help us understand the basis for a lot of interesting behavioral phenomena, including sociality,” he added.
Rats are social creatures. Much like humans, they interact with each other in ways that influence their behavior through complex social patterns of touching and body language. These rat interactions are not that far from our own, the researchers say.
Ölveczky gave a real-life example: “When people come into my lab, I scratch my head a little bit and soon after they will scratch their heads, or I cross my legs, and they cross their legs. We are subconsciously communicating with each other.”
Although studies of rat behavior have existed for years, in the past they relied on observation and a limited number of data points.
From videos, a machine-learning pipeline extracted more than 110 million 3D poses tracking various points on the rats’ bodies as they moved and interacted.
“The standard in the field is for somebody to just watch hours and hours of rat videos and say, ‘Oh, I think that they touched each other there. I think that this guy was mimicking the other guy,’” Ölveczky said.
The new study was able to take an in-depth look at how those social behaviors are communicated thanks to groundbreaking technology. From videos of the interactions, a machine-learning pipeline extracted more than 110 million 3D poses tracking various points on the rats’ bodies as they moved and interacted. Researchers could then graph how these animals behaved around others, including how they learned and changed through these exchanges.
“By having this methodology, we can replace the subjective human observer with a very rigorous and reproducible method for behavioral quantification and identification of particular gestures or even interaction motifs,” said Ölveczky.
AI also allowed the researchers to “analyze amounts of data that would take humans years and years to scroll through,” said Ugne Klibaite, a postdoctoral fellow in the Ölveczky Lab and lead author on the paper.
“Given how far computer vision and deep learning has progressed and the technology, the cameras, and the computers we have, we can actually get high-resolution animal movement in 3D,” said Klibaite. Now, she continued, “we have a chance to think about what that might mean.”
This advance is already opening new areas for research into autism. A complex disorder, autism probably has environmental components, said Ölveczky. It also seems clear, however, that there is a genetic component, with certain high-risk genes predisposing an individual to autism.
“The question then is how does a mutation or a knockout in this gene affect the brain, and how does that lead to changes in social behavior?”
With funding from the Simons Foundation for Autism Research, which provided rats that had variations in these specific genes, the researchers were able to look at how these genetically modified rats socialized.
While stressing that autism is a human condition, the researchers did find some intriguing parallels.
“This is a spectrum disorder, and we see some of that variability in our different rat models as well,” said Ölveczky.
Noting that children on the autism spectrum often socialize in different ways than children not on the spectrum, he said, “We also see a whole variety of different types of differences in social interactions in these rats that depend on the particular gene that was knocked out.”
Ongoing research will explore these similarities and how they might relate to the altered genes.
“Using this platform, we are going to ask questions about how different parts of the brain process social gestures,” said Ölveczky. “Can we go deeper and really pinpoint the circuits that are responsible for this difference in behavior? And when we can do that — if we can do that — then that could very well inspire new approaches to therapy.”
Adding to the value of the study, the data — the films of the rats and the movement trajectories distilled from them — will be shared, said Klibaite, who led the data collection and behavioral analysis.
“Hopefully by releasing this to the community and getting people to engage with the data as well, we’ll have people in the conversation making better models of how the brain underlies social behavior.”
Funding for this research came, in part, from the National Institutes of Health.
Health
Sniffing out signs of trouble
Mass General Brigham Communications
March 25, 2025
3 min read
Researchers develop at-home test to ID those at risk of Alzheimer’s years before symptoms appear
When it comes to early detection of cognitive impairment, a new study suggests that the nose knows.
Researchers from Harvard-affiliated Mass General Brigham developed olfactory tests — in which partic
Researchers develop at-home test to ID those at risk of Alzheimer’s years before symptoms appear
When it comes to early detection of cognitive impairment, a new study suggests that the nose knows.
Researchers from Harvard-affiliated Mass General Brigham developed olfactory tests — in which participants sniff odor labels that have been placed on a card — to assess people’s ability to discriminate, identify, and remember odors. They found that participants could successfully take the test at home and that older adults with cognitive impairment scored lower on the test than cognitively normal adults. Results are published in Scientific Reports.
“Early detection of cognitive impairment could help us identify people who are at risk of Alzheimer’s disease and intervene years before memory symptoms begin,” said senior author Mark Albers of the Laboratory of Olfactory Neurotranslation, the McCance Center for Brain Health, Department of Neurology at Massachusetts General Hospital, and an assistant professor of neurology at Harvard Medical School. “Our goal has been to develop and validate a cost-effective, noninvasive test that can be performed at home, helping to set the stage for advancing research and treatment for Alzheimer’s.”
Albers and colleagues are interested in whether olfactory dysfunction — the sometimes-subtle loss of sense of smell — can serve as an early warning sign for neurodegenerative diseases such as Alzheimer’s, Parkinson’s, chronic traumatic encephalopathy, and traumatic brain injury. Albers helped found a company that makes the Aromha Brain Health Test, which is the test used by the research team to conduct the current study.
To evaluate the olfactory test, the team recruited English- and Spanish-speaking participants with subjective cognitive complaints (those with self-reported concerns about memory) and participants with mild cognitive impairment. They compared these participants’ test results with those from people who had no sense of smell and with cognitively normal individuals.
The research team found that odor identification, memory, and discrimination declined with age. They also found that older adults with mild cognitive impairment had lower scores for odor discrimination and identification compared with older adults who were cognitively normal. Overall, the researchers found that test results were similar across English- and Spanish-speakers, and participants performed the test equally successfully regardless of whether they were observed by a research assistant.
The authors note that future studies could incorporate neuropsychological testing and could follow patients over time to see if the tool can predict cognitive decline.
“Our results suggest that olfactory testing could be used in clinical research settings in different languages and among older adults to predict neurodegenerative disease and development of clinical symptoms,” said Albers.
The study was funded by the National Institutes of Health.
Science & Tech
What are the odds of picking a perfect NCAA bracket?
Statistician explains why ‘it’s unlikely to happen in anyone’s lifetime’
March 24, 2025
2 min read
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
Kevin Rader is the senior preceptor in statistics and associate director of undergraduate
A series of random questions answered by Harvard experts.
Kevin Rader is the senior preceptor in statistics and associate director of undergraduate studies.
Typically, you’re talking about the perfect bracket of 64 games. Sixty-three teams lose and one team doesn’t, and to get the perfect bracket, you have to pick right in each of those games. The equation is 1 over 263, which is some astronomical number, it’s in the quintillions. It’s like winning the Powerball two drawings in a row.
No one has gotten a perfect bracket ever, or at least not that has been reported. This year, we’re about halfway through the games, and there are no perfect brackets remaining of all the publicly available ones. It’s unlikely to happen in anyone’s lifetime.
The top seeds almost never lose, at least not in the first round. So it’s not really like flipping 63 coins; it’s like flipping 47 coins. So the chances are more like winning the lottery twice out of the next three draws.
The best chance for anyone to get a perfect bracket is if all the best teams win. But there are always going to be some upsets — and good luck correctly picking those.
Winning your office pool is almost a more difficult question. It mainly depends on how many people are in the pool. You need to distinguish yourself from your competition. Yes, you pick the favorites most of the time, but you have to pick a few upsets to distinguish yourself from other people, especially if it’s in a big pool with lots of entries.
To pick the upsets correctly, use the information you can. At a certain point, it’s almost a coin flip, but when there’s a big discrepancy between the teams, you shouldn’t use a coin flip; you should pick chalk.
Campus & Community
Maybe a teacher. Or maybe an education policy reformer.
Andrew Zonneveld, who grew up on a military base in North Carolina, is studying government and education.Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
March 21, 2025
4 min read
Andrew Zonneveld believes public service is way to make a real difference in world
Andrew Zonneveld se
Maybe a teacher. Or maybe an education policy reformer.
Andrew Zonneveld, who grew up on a military base in North Carolina, is studying government and education.
Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
4 min read
Andrew Zonneveld believes public service is way to make a real difference in world
Andrew Zonneveld sees teaching as the most important job in the world.
“Doctors are great. But doctors are only doctors because they had great teachers,” said the first-generation college student from North Carolina.
Zonneveld ’26, a government concentrator with a secondary in education studies, is attending Harvard College on full financial aid. Graduating debt-free means he can prioritize public service.
“I would love to be a public school teacher for a few years,” said the Leverett House resident.
“He talks a great deal about going back to North Carolina and helping the schools there,” said his mom, Jennifer Eirich. “I think it has a lot to do with the strong connections he formed with the teachers he had as a kid. But I guess I think there’s something bigger out there for him. Maybe he’ll go and change the educational system for the whole country. Maybe he’ll go into politics.”
Zonneveld, who grew up on a military base and counts many servicemembers in his family, has been interested in the intersection of education and policy from an early age. He recalled pitching an elementary school teacher on forming the school’s first student government.
“I won president in third grade or fourth grade,” he said. “In my speech, I promised the principal would kiss a pig if we raised enough money through Box Tops — remember those?”
Entering Onslow Early College High School — where students work toward their diplomas while earning free credits from Coastal Carolina Community College — provided Zonneveld with his next opening. He spent the summer before ninth grade drafting a constitution for the student government association he later helped launch at the newly opened public high school.
“I could tell from the beginning how motivated he was,” remembered Hannah Padilla, a former guidance counselor there. “Within a week or two, he had come out of his shell and was just unapologetically Andrew: a dedicated student who knew exactly what he wanted from life.”
The Class of 2022 valedictorian assumed he would attend North Carolina’s flagship public university. The school offered him a generous scholarship. “But it was still going to cost me 15 or 20 grand per year,” Zonneveld said.
Opening an acceptance letter from Harvard College was a tearful occasion — and a total surprise after applying on a last-minute whim. “Not in a million years did someone from our county think something like this could happen,” Eirich said.
The family had been concerned about covering college costs, so the University’s offer came as a big relief. “Financial aid is really the only reason I’m here at Harvard,” he said. “It’s the only way I can afford it.”
The support also means Zonneveld’s attentions are no longer so splintered. He had trained as a lifeguard in his early teens, and sometimes worked full-time at area pools while attending high school.
At Harvard, Zonneveld has continued teaching aquatics at the Malkin Athletic Center. But only because he still enjoys passing on his knowledge. “I don’t have to work crazy hours,” he said.
Help from Harvard also made other opportunities possible. Zonneveld was able to complete an internship last summer at a research institute in Berlin with the support of the Government Department. He also traveled to Thailand and Vietnam with Harvard Model Congress to teach high schoolers about policy and public speaking. Over spring break, he helped the organization run a government simulation with teens in Brussels.
“Financial aid didn’t just bring me here,” Zonneveld said. “It allowed me to travel the world, to go home and see my family during breaks. It allowed me to have access to opportunities I would have never had anywhere else.”
Campus & Community
Passion for advocacy nurtured at home
Maryam Guerrab, who is from North Carolina, is studying government on the political economy track.Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
March 21, 2025
4 min read
Maryam Guerrab, a child of Algerian immigrants, seeks to combine important lessons from classroom with powerful ones from life
Marya
Maryam Guerrab, who is from North Carolina, is studying government on the political economy track.
Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
4 min read
Maryam Guerrab, a child of Algerian immigrants, seeks to combine important lessons from classroom with powerful ones from life
Maryam Guerrab says her upbringing, as one of five children of Algerian immigrants, fueled her passion for advocacy.
“Public service work is incredibly important to me, I think in large part because of how I grew up. I come from a large immigrant family whose parents are both blue-collar workers,” Guerrab said. “I’ve seen a lot of the obstacles that different communities face through both my personal experiences and professional experiences I’ve pursued.”
At Harvard, Guerrab is concentrating in government on the political economy track.
“I thought that studying government, learning more about the local and economic institutions that shape the world we live in today, informing how many people lead their lives and the problems they face, would be the best way to advocate for people’s rights,” she said.
Guerrab, now just months away from graduation, was apprehensive about applying.
“I did not think Harvard was an option for me. It seemed this almost mystical place where the upper echelons of society would go, and that was not me,” said the 21-year-old from North Carolina. “I was privileged enough to know that I was going to go to college, but I thought it would be a state school or somewhere nearby.”
She learned about Harvard’s financial aid program in high school but joked with her family that she’d probably never get in anyway.
“There was this confidence from them when I told them I was applying,” she said of her parents. “I was like, ‘Mama, I don’t really know if you realize that very few people get in, and I don’t know if I can do it.’ And it was always, ‘It’s fine! It’ll be OK.’”
Mama turned out to be right.
Guerrab said getting assistance and not having to worry about paying for college has allowed her “to thrive as a student, pursue opportunities that potentially wouldn’t have been possible.”
She also received a launch grant, which is part of the support students on full financial aid receive to help pay for post-Harvard needs such as Medical College Admission Test-prep guides (she is planning to apply in May) and books.
She later added: “I recognize all the privilege that I have been given, and I want to use it to give back.”
Guerrab said she felt she has made the biggest impact during her College career as a case management director for Y2Y Network, which provides overnight housing for unhoused young adults in Greater Boston. The opportunity allowed her to engage with young people in the program and mentor other Harvard student volunteers.
“What drives my persistent pursuit of both my academics and community service work is my passion to give the best service I can and to take advantage of every opportunity,” Guerrab said. “Harvard is a once-in-a-lifetime experience — on the academic end, [being able to] learn from people with such diverse experiences. Harvard provides me an opportunity to learn as much as I can about the fields that I’m passionate about.”
She continued: “Taking what I learned in the classroom to inform how I’m interacting with the communities that I serve is super important.”
Between classes and volunteer work, Guerrab stepped out of her comfort zone and joined the mountaineering club on campus. She acknowledged that growing up, outdoor activities weren’t as accessible.
“I didn’t even think it was something I wanted to explore,” she said. “The Mountaineering Club was definitely something that I was like, ‘I’m just gonna try something crazy and see what happens.’”
Guerrab said her first mountaineering trip to the Boston Basin of the North Cascade National Park in Washington was a mental, physical, and personal “growth moment” that made her aware of her resilience.
“It was something that taught me that I can really do anything, even in really hard moments,” she said.
Campus & Community
Her parents came from India. She wants to help other newcomers.
Merlin D’souza from Casa Grande, Arizona, studies human developmental and regenerative biology and hopes to go into medicine.Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
March 21, 2025
4 min read
Merlin D’souza has her sights set on medical school
Merlin D’souza learned abo
Her parents came from India. She wants to help other newcomers.
Merlin D’souza from Casa Grande, Arizona, studies human developmental and regenerative biology and hopes to go into medicine.
Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
4 min read
Merlin D’souza has her sights set on medical school
Merlin D’souza learned about artificial wombs in her high school Career Technical Education biotechnology class. That experience led her to look for unique biomedical programs when considering colleges. Harvard’s Human Developmental and Regenerative Biology Department immediately caught her attention.
“They were working with stem cells and doing projects that focused on the regenerative aspect of medicine,” said the senior from Casa Grande, Arizona. “As someone who wants to go into medicine and wants to be part of the technology and development [side], that was really exciting for me.”
D’souza, a concentrator in human developmental and regenerative biology and global health and health policy, has really enjoyed her time at Harvard, but the road to Cambridge was not entirely smooth. Her family was unsure how they would be able to afford paying for school. Immigrants from India, her father left school at a young age to begin working to support his family, while her mother was also unable to continue her education.
“My mom had a love and dream to go and study, but she had to help her mom in the rice fields and the farm. She always was like, ‘Wherever you want to shoot, however high you want to go, we’ll support you.’ Harvard was that [for me],” she said.
Getting full financial aid from Harvard allowed her to attend worry-free. “Tuition and the grants that I’ve been able to receive have been super helpful, because I’m not shifting the burden on my parents. That was a big concern for me,” she said. “Having that support as I study and go through this hard curriculum has been such a relief.”
D’souza took full advantage of the opportunities she found. During the last four years, she has traveled to India to teach at under-resourced schools, conducted research on mental health with the help of the Boston Public Health Commission, and presented research to the Massachusetts Association for Mental Health.
Financial aid assistance not only has made attendance possible, but also helped D’souza pursue medical school. In the fall of her junior year, she received a launch grant designed to help students transition from Harvard. With that money she was able to pay for the Medical College Admission Test and cover the costs of applications. She highlighted other support available to financial aid students like herself, including funds to buy a winter coat.
“The reason I want to go to medical school is mostly because I want to help populations from the communities I came up in. My parents were immigrants. They didn’t have access to the best medical resources,” she said.
Outside of academics, D’souza has found ways to give back. She serves as a peer advising fellow with the Advising Programs Office, where she supports first-years as they transition to college. She also volunteers at the Harvard Square Homeless Shelter and at Boston Children’s Hospital.
“We get a chance to provide support to and play with a kid going through dialysis. It’s really the highlight of my week,” she said.
After graduation, D’souza will take a gap year to teach or do research before starting medical school, a break that she said wouldn’t have been possible if she was saddled with a lot of loan debt.
“One thing that people don’t think about with tuition assistance is that most people need it,” she said. “Tuition assistance has such a long-reaching impact. I’m able to have this education and pursue a degree in a profession that helps to give back. It’s kind of like a full circle.”
Outside of class, Morgan Byers works as an EMT with Crimson EMS and conducts research at Boston Children’s Hospital.Niles Singer/Harvard Staff Photographer
Campus & Community
Providing medical care is important, but so is ensuring access
Morgan Byers grew up in a small Georgia community with big ideas of how to help
Nikki Rojas
Harvard Staff Writer
March 21, 2025
4 min read
Morgan Bye
Providing medical care is important, but so is ensuring access
Morgan Byers grew up in a small Georgia community with big ideas of how to help
Nikki Rojas
Harvard Staff Writer
4 min read
Morgan Byers grew up in Commerce, Georgia, a community of about 8,200 residents, where she saw how limited access to medical care can be. She was particularly interested in the disproportionately high maternal mortality rate in the South.
“The South has the worst maternal mortality rates in the country, which is due to a complicated recipe of racial and gender discrimination, socioeconomic inequity, and limited access to reproductive health care,” said Byers ’26. “It absolutely breaks my heart that as medicine advances, these regions and women are entirely left behind, coping with the same maternal mortality rate in 2025 that was present in Massachusetts in the 1970s.”
That perspective inspired the Pforzheimer resident’s desire to become a doctor and led her to pursue an interdisciplinary approach to her studies.
“I eventually decided to study human developmental and regenerative biology out of the Harvard Stem Cell Institute, which is super research-heavy. I paired that with government, so that I can study medicine, research, and then access,” the double concentrator said.
“My ultimate goal is to focus on bringing access to individuals in rural medical deserts to curb preventable disease.”
Morgan Byers
Harvard proved to be “a transformative experience” that allowed her to “study absolutely everything,” she said. The summer after her first year, Byers headed to Portugal through the Office of International Education to study with its country’s doctors.
“I was fascinated by Portugal’s universal health care system after learning about it in a health care economics class,” Byers shared. “That summer, I woke up every day and studied a different specialty, being enthralled by the medical knowledge I was picking up. But I was even more fascinated by the health care system and how policy directly impacts medical practice.”
Beyond academics, Byers works as an EMT with Crimson EMS and conducts research at the Breault Lab at Boston Children’s Hospital. At the lab, Byers works on intestinal organoids and enteroendocrine cells under the supervision of Daniel Zeve, an endocrinologist and lecturer on pediatrics at Harvard Medical School.
She also works as a campus tour guide and mentors Boston high school students through the Emerging Leaders Program at Radcliffe Institute.
Although she has taken full advantage of her time at the College, Byers said she wasn’t always sure she would be able to attend. “Nobody in my family had ever gone to college before,” she said. Her mother works as an administrative assistant at a high school, and her father works in equipment management.
She added: “I definitely did not think Harvard was an option for me. I honestly didn’t want to get myself excited about that possibility and it just to be ripped away.”
Even after she was accepted, Byers said her family remained concerned about covering costs. “It’s truly the biggest blessing in the world,” she said. “I was worried that I was going to have to say no because of money, but because of significant tuition assistance that was not the case.”
Her mom, Mandy Byers, added: “If it was not for Harvard’s financial aid program and all the wonderful people at the admissions office that we talked to in the beginning, I don’t know that it would have been an option for her.”
The 21-year-old wants to attend medical school in the South, where she hopes to make an impact on health care access. Several of her Harvard courses have highlighted for her the importance of implementation science, or the study of methods to promote evidence-based practices into public health care.
“I dreamed of being a bridge between the resource epicenters of the world, like Harvard, and the places so desperately in need of that research,” she said. “Those places were small towns all over the South, just like the tiny ones that I come from. My ultimate goal is to focus on bringing access to individuals in rural medical deserts to curb preventable disease.”
“Morgan has more ambition and drive than most adults,” her mother said. “She wants to help people, and I really can’t see her doing anything else. Even if medicine doesn’t work out, it’s going to be serving people in some capacity.”
Byers acknowledged that some students come to college with a clear idea of their path through higher education and beyond. “I’ve tried very consciously to not make it like that at all,” she said. “I’ve tried to be very grateful of the fact that I get to pave my own way at every turn.”
Nation & World
What happens to your data if 23andMe collapses?
Jon Elswick/AP
Liz Mineo
Harvard Staff Writer
March 20, 2025
8 min read
Health law policy expert says biotech firm’s uncertain future shows need for protections of personal, genetic info
A recent paper published in the New England Journal of Medicine calls for regulations to protect customers’ personal and genetic data in
Health law policy expert says biotech firm’s uncertain future shows need for protections of personal, genetic info
A recent paper published in the New England Journal of Medicine calls for regulations to protect customers’ personal and genetic data in light of biotech company 23andMe’s uncertain future.
The genetic testing firm became wildly popular after launching in 2007, with millions of customers sending in saliva samples for analysis to learn about their ancestry and genetic makeup.
The company was valued at $6 billion, or $17.65 a share, shortly after going public in 2021. It has since fallen to about $48 million, or $1.78 per share, after a 2023 data breach and resignation of some board members. The firm said in January that it’s exploring “strategic alternatives,” including a sale of the company or assets, restructuring, or business combination, among other options.
In this edited conversation, I. Glenn Cohen, one of the paper’s authors and faculty director of the Petrie-Flom Center at Harvard Law School, explains the legal landscape surrounding genetic data, the reasons for more consumer protection laws, and the steps for consumers to protect their personal and genetic data.
I. Glenn Cohen.
File photo by Niles Singer/Harvard Staff Photographer
If 23andMe were to file for bankruptcy protection, what might happen with the genetic data of 14 million people the company holds?
As 23andMe faces significant financial distress and might be purchased directly or go bankrupt and its assets sold, all of the genetic and health information provided by people is a valuable asset to the company. Many people have used services like 23andMe, Ancestry.com, and others which are direct-to-consumer genetic tests companies, to answer questions about their ancestry or their genetic code.
But in the course of answering these questions for themselves, they’ve also contributed to these huge genetic databases. Our concern is that they may end up in the hands of somebody other than 23andMe, in a way that many people who have given their information to 23andMe never contemplated and might object to.
What are the possible case scenarios, and what are your concerns?
One is about data security. We saw that 23andMe itself was subject to a massive data breach in 2023, and if the company that takes over the data lacks good data security, there’s a possibility of breach.
Interestingly, once upon a time, the Pentagon told military personnel not to use these at-home DNA kits because it was concerned about national security. A more quotidian concern is that your genetic information might become available to others, and it’s possible you could become reidentified.
To give you an example from a study several years ago, a number of researchers used genetic data to try to identify, through what’s called genome-wide association studies (GWAS) technology and approach, what parts of the genome were associated with being gay. Many people who had given their genetic information were understandably upset at the idea this could be a possible use of their information.
So, while customers have made the decision to share with 23andMe, from whom they get a lot of benefit, they really have very little say about what will happen should the company be taken over or should the company go bankrupt, and its assets sold.
“I would love to see a space where people can get the information they want without feeling as though that information might put them at risk.”
Do federal health privacy regulations offer privacy protections to consumers?
The Health Insurance Portability Accountability Act (HIPAA) is the law that, among other things, when you speak to your doctor, creates rules about what can be shared under what context.
The problem is that HIPAA’s definition of covered entities and business associates means that when you have provided information, including your genetic data, not to a hospital system, not to a physician, but to a direct-to-consumer company like 23andMe, you are not covered by HIPAA. You are treated by the law essentially as a consumer, not as the patient.
Now, there are other federal laws that cover you a little bit. The Genetic Information Nondiscrimination Act prevents health insurers, but also employers, from using genetic information in a way that is discriminatory. So that kind of law still will apply, but health privacy laws at the federal level won’t directly apply when you are dealing with a private company like 23andMe.
What about the privacy protections 23andMe offers to consumers?
We should say at the front end that it asks its consumers for consent to use their data for research purposes. There is the option not to consent although roughly 80 percent of the consumers have given consent.
The consumer agreements have a privacy statement that says all U.S. customers have certain rights, such as a right to opt out of the storage of saliva samples and the right to request the deletion of their account. It also says that it doesn’t share individual-level information, on diseases or genotypes, or de-identify information voluntarily with insurance companies, employers, public databases, or law enforcement agencies without a subpoena.
But the company shares personal information with service providers and contractors for sample analysis, marketing, and analytics. Also, the privacy statement reserves the company’s right to transfer customers’ personal information in the event of a sale or bankruptcy, and customers can’t protect their data from being accessed, sold, or transferred as part of that transaction.
Can bankruptcy laws offer some safeguards to 23andMe consumers?
One of the paper’s co-authors, Melissa Jacoby, is a bankruptcy law scholar. My specialty is health law, but I’ll do my best to explain. Many companies that have held sensitive information have filed for bankruptcy, and in the course of that bankruptcy they’ve sold consumer data to a third party.
Bankruptcy law offers some protections. Bankruptcy itself is a public process. There’s attention from the public, and sometimes regulators, like the [Federal Trade Commission] or state attorney generals, can get involved in cases and can seek to enter the bankruptcy proceedings. A federal court oversees a bankruptcy, and the U.S. Trustee Program, an agency within the Department of Justice, can sometimes get involved as well.
In some instances, bankruptcy law had required a consumer privacy ombudsperson to investigate a sale and determine whether it’s keeping with the bankrupt company’s privacy statements, as well as the law.
These are some protections, but they’re not perfect. One thing we want to highlight is that when most people have given their genetic information, they’ve never thought about this, and we just want people to pay attention to it.
What are your policy recommendations to protect consumers’ personal and genetic data?
The U.S. has a federal health privacy law that’s a bit out of date compared to our peer countries in Europe. One solution to this problem would be to have more general data privacy protection that would cover all personal data, including genetic data, and that would apply in bankruptcy cases as well.
There have been many attempts to get Congress to comprehensively update federal privacy law, including health privacy laws. They haven’t really succeeded. So, we’re not holding our breath.
A more targeted approach might be thinking about expanding the scope of the HIPAA law to cover companies like 23andMe, or potentially expanding what the Genetic Information Nondiscrimination Act covers, in terms of discrimination and genetic information. New regulations could also address instances when you have the overlap of a company that has genetic information and goes bankrupt. That’s what we’d like to see. Whether it will happen, I’m not sure.
What could consumers do in the meantime?
Going forward, I would think about these things as you decide whether the kind of information you are going to get from a direct-to-consumer company like 23andMe is worth the risks.
Also, when you are given the right to choose not to consent to sharing of data, I think that’s worth thinking about. And if this is something that worries you, this might be a time to go in and delete that information in your account, even though it’s not a perfect solve.
There are a lot of reasons why people are curious about their ancestry or genetic information. My hope is that this experience might also cause companies to be more privacy sensitive. I would love to see a space where people can have their cake and eat it too, to get the information they want without feeling as though that information might put them at risk if there’s a bankruptcy and the like.
Campus & Community
Women’s basketball on the road to March Madness
Ivy League champs return for first time in 18 years
Nick Economides
Harvard Correspondent
March 20, 2025
3 min read
Coach Carrie Moore and her Ivy League champs depart for the airport.Photos by Christina Richson/Harvard Athletics
The Harvard Women’s Basketball team headed to North Carolina on Thursday as the No. 10 see
Ivy League champs return for first time in 18 years
Nick Economides
Harvard Correspondent
3 min read
Coach Carrie Moore and her Ivy League champs depart for the airport.
Photos by Christina Richson/Harvard Athletics
The Harvard Women’s Basketball team headed to North Carolina on Thursday as the No. 10 seed in the upcoming NCAA Women’s Basketball Tournament, marking the squad’s first trip to March Madness in 18 years. The flight to Raleigh came days after a thrilling 74-71 Crimson victory last Saturday against Columbia that gave the team its first-ever Ivy League Tournament Championship.
The Ivy League Tournament Championship trophy on display.
“I couldn’t be more proud of my team and the staff,” said the third-year coach. “It was a dramatic way to end the tournament, but if it didn’t end that way, it wouldn’t be us. You couldn’t write the story any better. It makes everything we’ve gone through over the last three years worth it.”
Moore said she is especially proud of how the team battled moments of adversity.
“I’ve always told our team, ‘You either win or you learn,’” she said. “That’s who we are. That’s our makeup. We are a resilient group. We’ve done a really good job this season of having a ‘next-play mentality’ and focusing on the process and not the outcome. We knew we were going to take these games one possession at a time, and one timeout at a time, and we never panicked.”
“From the top down, I’m so proud of the program,” said team captain and forward Katie Krupa ’26. “Coach Moore has done an excellent job handling each and every challenge.
“It was such an overwhelming feeling of joy and pride in the group. Everything we worked for and wanted was building to that moment. We’ve all really jelled this year and got the dynamics right off and on the court. This sisterhood is as strong as it’s ever been,” she added.
The Crimson, led by senior Harmoni Turner, who scored 44 points to help the Crimson reach the Ivy League championship, will play No. 7 seed Michigan State on Saturday afternoon. Moore said Harvard is ready for the national spotlight, and eager to make its presence known to the nation.
“We’re not just excited to be there,” Moore said. “We’re excited to go into this tournament, play really well, and win some games this weekend.”
“You go through so many peaks and valleys on and off the court during a season, it’s all about how you respond each time you hit that valley, and we’ve responded excellently every time this season,” added Krupa. “We have nothing to lose. We can go out there and show the world what we’re made of.”
Liz Zonarich/Harvard Staff
Campus & Community
4 things we learned this week
Sy Boles
Harvard Staff Writer
March 20, 2025
1 min read
How closely have you been following the Gazette? Take our quiz to find out.
The rent is too dang high. A global crisis led to lifesaving innovations. Sugar cravings are real, but sugar addiction might not be. Loving your job has downsides.
Photo illustrations by Judy Blomquist/Harvard Staff
Health
Machine healing
Alvin Powell
Harvard Staff Writer
March 20, 2025
long read
Artificial intelligence is up to the challenge of reducing human suffering, experts say. Are we?
When Adam Rodman was a second-year medical student in the 2000s, he visited the library for a patient whose illness had left doctors stumped. Rodman searched t
Artificial intelligence is up to the challenge of reducing human suffering, experts say. Are we?
When Adam Rodman was a second-year medical student in the 2000s, he visited the library for a patient whose illness had left doctors stumped. Rodman searched the catalog, copied research papers, and shared them with the team.
“It made a big difference in that patient’s care,” Rodman said. “Everyone said, ‘This is so great. This is evidence-based medicine.’ But it took two hours. I can do that today in 15 seconds.”
Rodman, now an assistant professor at Harvard Medical School and a doctor at Beth Israel Deaconess Medical Center, these days carries a medical library in his pocket — a smartphone app created after the release of the large language model ChatGPT in 2022. OpenEvidence — developed in part by Medical School faculty — allows him to query specific diseases and symptoms. It searches the medical literature, drafts a summary of findings, and lists the most important sources for further reading, providing answers while Rodman is still face-to-face with his patient.
“We say, ‘Wow, the technology is really powerful.’ But what do we do with it to actually change things?”
Adam Rodman
Artificial intelligence in various forms has been used in medicine for decades — but not like this. Experts predict that the adoption of large language models will reshape medicine. Some compare the potential impact with the decoding of the human genome, even the rise of the internet. The impact is expected to show up in doctor-patient interactions, physicians’ paperwork load, hospital and physician practice administration, medical research, and medical education.
Most of these effects are likely to be positive, increasing efficiency, reducing mistakes, easing the nationwide crunch in primary care, bringing data to bear more fully on decision-making, reducing administrative burdens, and creating space for longer, deeper person-to-person interactions.
Adam Rodman, assistant professor at Harvard Medical School and physician at Beth Israel Deaconess Medical Center
“The optimist in me hopes that AI can make us doctors better versions of ourselves to better care for our patients.”
ADAM RODMAN: I am obsessed with metacognition, with thinking about thinking. So what excites me most about AI and medicine? Well, the optimist in me hopes that AI and medicine can make us doctors better versions of ourselves to better care for our patients. I think the best case scenario for me is a world in which an artificial intelligence is communicating with me and my patients, looking for signs of implicit bias, looking for signs that I might be making the wrong decision, and more importantly, feeding back that information to me so that I can improve over time, so that I can become a better human. My worry is actually directly related to this. These are very powerful reasoning technologies, and really what is medical education other than a way to frame and shape the medical mind? So part of my worry is that because these technologies are so powerful, they’ll shortcut many of the ways that we know that doctors learn and get better, and we may end up with generations of physicians who don’t know how to think the best. I don’t think that this is the foregone conclusion, but it really is my worry about the way that things are going.
But there are serious concerns, too.
Current data sets too often reflect societal biases that reinforce gaps in access and quality of care for disadvantaged groups. Without correction, these data have the potential to cement existing biases into ever-more-powerful AI that will increasingly influence how healthcare operates.
Another important issue, experts say, is that AIs remain prone to “hallucination,” making up “facts” and presenting them as if they are real.
Then there’s the danger that medicine won’t be bold enough. The latest AI has the potential to remake healthcare top to bottom, but only if given a chance. The wrong priorities — too much deference to entrenched interests, a focus on money instead of health — could easily reduce the AI “revolution” to an underwhelming exercise in tinkering around the edges.
“I think we’re in this weird space,” Rodman said. “We say, ‘Wow, the technology is really powerful.’ But what do we do with it to actually change things? My worry, as both a clinician and a researcher, is that if we don’t think big, if we don’t try to rethink how we’ve organized medicine, things might not change that much.”
Shoring up the ‘tottering edifice’
Five years ago, when asked about AI in healthcare, Isaac Kohane responded with frustration. Teenagers tapping away on social media apps were better equipped than many doctors. The situation today couldn’t be more different, he says.
Kohane, chair of the Medical School’s Department of Biomedical Informatics and editor-in-chief of the New England Journal of Medicine’s new AI initiative, describes the abilities of the latest models as “mind boggling.” To illustrate the point, he recalled getting an early look at OpenAI’s GPT-4. He tested it with a complex case — a child born with ambiguous genitalia — that might have stymied even an experienced endocrinologist. Kohane asked GPT-4 about genetic causes, biochemical pathways, next steps in the workup, even what to tell the child’s parents. It aced the test.
“This large language model was not trained to be a doctor; it’s just trained to predict the next word,” Kohane said. “It could speak as coherently about wine pairings with a vegetarian menu as diagnose a complex patient. It was truly a quantum leap from anything that anybody in computer science who was honest with themselves would have predicted in the next 10 years.”
Isaac Kohane, chairman of Harvard Medical School’s Department of Biomedical Informatics and editor-in-chief of the New England Journal of Medicine’s new AI journal
“Having an instant second opinion after any interaction with a clinician will change, for the better, the nature of the doctor-patient relationship.”
ISAAC KOHANE: I am most excited that AI is going to transform the patient experience. Just merely having an instant second opinion after any interaction with a clinician will change to the better the nature of the doctor-patient relationship. Also, with regard to what things I fear could go wrong, it’s that parties that do not have the patient’s best interest will be the ones steering the tendencies/biases or prejudices of our new AI companions.
And none too soon. The U.S. healthcare system, long criticized as costly, inefficient, and inordinately focused on treatment over prevention, has been showing cracks. Kohane, recalling a faculty member new to the department who couldn’t find a primary care physician, is tired of seeing them up close.
“The medical system, which I have long said is broken, is broken in extremely obvious ways in Boston,” he said. “People worry about equity problems with AI. I’m here to say we have a huge equity problem today. Unless you’re well connected and are willing to pay literally thousands of extra dollars for concierge care, you’re going to have trouble finding a timely primary care visit.”
Early worries that AI would replace physicians have yielded to the realization that the system needs both AI and its human workforce, Kohane said. Teaming nurse practitioners and physician assistants with AI is one among several promising scenarios.
“It is no longer a conversation about, ‘Will AI replace doctors,’ so much as, ‘Will AI, with a set of clinicians who may not look like the clinicians that we’re used to, firm up the tottering edifice that is organized medicine?’”
Building the optimal assistant
How LLMs were rolled out — to everyone at once — accelerated their adoption, Kohane says. Doctors immediately experimented with eye-glazing yet essential tasks, like writing prior authorization requests to insurers explaining the necessity of specific, usually expensive, treatments.
“People just did it,” Kohane said. “Doctors were tweeting back and forth about all the time they were saving.”
Patients did it too, seeking virtual second opinions, like the child whose recurring pain was misdiagnosed by 17 doctors over three years. In the widely publicized case, the boy’s mother entered his medical notes into ChatGPT, which suggested a condition no doctor had mentioned: tethered cord syndrome, in which the spinal cord binds inside of the backbone. When the patient moves, rather than sliding smoothly, the spinal cord stretches, causing pain. The diagnosis was confirmed by a neurosurgeon, who then corrected the anatomic anomaly.
One of the perceived benefits of employing AI in the clinic, of course, is to make doctors better the first time around. Greater, faster access to case histories, suggested diagnoses, and other data is expected to improve physician performance. But plenty of work remains, a recent study shows.
Research published in JAMA Network Open in October compared diagnoses delivered by an individual doctor, a doctor using an LLM diagnostic tool, and an LLM alone. The results were surprising, showing an insignificant improvement in accuracy for the physicians using the LLM — 76 percent versus 74 percent for the solitary physician. More surprisingly, the LLM by itself did best, scoring 16 percentage points higher than physicians alone.
Rodman, one of the paper’s senior authors, said it’s tempting to conclude that LLMs aren’t that helpful for doctors, but he insisted that it’s important to look deeper at the findings. Only 10 percent of the physicians, he said, were experienced LLM users before the study — which took place in 2023— and the rest received only basic training. Consequently, when Rodman later looked at the transcripts, most used the LLMs for basic fact retrieval.
“The best way a doctor could use it now is for a second opinion, to second-guess themselves when they have a tricky case,” he said. “How could I be wrong? What am I missing? What other questions should I ask? Those are the ways, we know from psychological literature, that complement how humans think.”
Among the other potential benefits of AI is the chance to make medicine safer, according to David Bates, co-director of the Center for Artificial Intelligence and Bioinformatics Learning Systems at Mass General Brigham. A recent study by Bates and colleagues showed that as many as one in four visits to Massachusetts hospitals results in some kind of patient harm. Many of those incidents trace back to adverse drug events.
“AI should be able to look for medication-related issues and identify them much more accurately than we’re able to do right now,” said Bates, who is also a professor of medicine at the Medical School and of health policy and management at the Harvard T.H. Chan School of Public Health.
David Bates,co-director of the Center for Artificial Intelligence and Bioinformatics Learning Systems at Mass General Brigham
“AI has a tendency to hallucinate, and that is a worry, because we don’t want things in people’s records that are not really there.”
DAVID BATES: AI has a great deal of promise. Burnout is rampant in many parts of medicine, especially, for example, primary care, and artificial intelligence will make many routine tasks like documentation much faster. Ambient scribes in particular are already doing that. There are also concerns about things going wrong. There are many ways that any time gains could be used, for example, just to increase physician workloads. It’s also very important that medical records be correct, and AI has a tendency to hallucinate, and that is a worry, because we don’t want things in people’s records that are not really there.
Another opportunity stems from AI’s growing competence in a mundane area: notetaking and summarization, according to Bernard Chang, dean for medical education at the Medical School.
Systems for “ambient documentation” will soon be able to listen in on patient visits, record everything that is said and done, and generate an organized clinical note in real time. When symptoms are discussed, the AI can suggest diagnoses and courses of treatment. Later, the physician can review the summary for accuracy.
Automation of notes and summaries would benefit healthcare workers in more than one way, Chang said. It would ease doctors’ paperwork load, often cited as a cause of burnout, and it would reset the doctor-patient relationship. One of patients’ biggest complaints about office visits is the physician sitting at the computer, asking questions and recording the answers. Freed from the note-taking process, doctors could sit face-to-face with patients, opening a path to stronger connections.
“It’s not the most magical use of AI,” Chang said. “We’ve all seen AI do something and said, ‘Wow, that’s amazing.’ This is not one of those things. But this program is being piloted at different ambulatory practices across the country and the early results are very promising. Physicians who feel overburdened and burnt out are starting to say, ‘You know what, this tool is going to help me.’”
Bernard Chang, Harvard Medical School Dean for Medical Education
“I see AI as a transformative tool on par with the availability of the internet in terms of its effect on medicine and medical education.”
BERNARD CHANG: What most excites me about AI’s promise in medicine is that these technological tools will allow physicians to spend more time on the human aspects of the profession, which is sorely needed, while facilitating the ability to access information quickly, analyze large amounts of important data, and make the difficult connections necessary to consider the rare diagnoses, the less obvious treatment paradigms, and ultimately the optimal care for patients. In medical education, students can use AI tools to accelerate their learning and move more quickly beyond rote practice to higher levels of cognitive analysis on their way to becoming the most outstanding doctors of the future. Whether things might go long lies in our hands. We need to be cautious about hallucinations and misinformation, bias, an erosion of fundamentals in learning, and an over-reliance on machines. As a society, we need to be mindful of the environmental impacts of the high energy costs involved. On the whole, I see AI as a transformative tool on par with the availability of the internet in terms of its effect on medicine and medical education.
The bias threat
For all their power, LLMs are not ready to be left alone.
“The technology is not good enough to have that safety level where you don’t need a knowledgeable human,” Rodman said. “I can understand where it might have gone aground. I can take a step further with the diagnosis. I can do that because I learned the hard way. In residency you make a ton of mistakes, but you learn from those mistakes. Our current system is incredibly suboptimal but it does train your brain. When people in medical school interact with things that can automate those processes — even if they’re, on average, better than humans — how are they going to learn?”
Doctors and scientists also worry about bad information. Pervasive data bias stems from biomedicine’s roots in wealthy Western nations whose science was shaped by white men studying white men, says Leo Celi, an associate professor of medicine and a physician in the Division of Pulmonary, Critical Care and Sleep Medicine at Beth Israel Deaconess Medical Center.
Leo Celi, associate professor of medicine and a physician in Beth Israel Deaconess Medical Center’s Division of Pulmonary, Critical Care and Sleep Medicine
“We need to design human AI systems, rather than build algorithms. We have to be able to predict how humans will mess up.”
LEO CELI: AI could be the Trojan horse we’ve been waiting for to redesign systems from a clean slate. I am talking about systems for knowledge creation, health care delivery, and eduction, which are all quite broken. The legacy of AI is to make us better critical thinkers, by putting data at the front and center, and making the breadth and the depth of the problems crystal clear. But we need to design human AI systems, rather than build algorithms. We have to be able to predict how humans will mess up. The designs should be similar those of systems for aviation, road safety, space, nuclear power generation. We need psychologists, cognitive scientists, behavioral economists, anthropologists to design human AI systems.”
“You need to understand the data before you can build artificial intelligence,” Celi said. “That gives us a new perspective of the design flaws of legacy systems for healthcare delivery, legacy systems for medical education. It becomes clear that the status quo is so bad — we knew it was bad and we’ve come to accept that it is a broken system — that all the promises of AI are going bust unless we recode the world itself.”
Celi cited research on disparities in care between English-speaking and non-English speaking patients hospitalized with diabetes. Non-English speakers are woken up less frequently for blood sugar checks, raising the likelihood that changes will be missed. That impact is hidden, however, because the data isn’t obviously biased, only incomplete, even though it still contributes to a disparity in care.
“They have one or two blood-sugar checks compared to 10 if you speak English well,” he said. “If you average it, the computers don’t see that this is a data imbalance. There’s so much missing context that experts may not be aware of what we call ‘data artifacts.’ This arises from a social patterning of the data generation process.”
Bates offered additional examples, including a skin cancer device that does a poor job detecting cancer on highly pigmented skin and a scheduling algorithm that wrongly predicted Black patients would have higher no-show rates, leading to overbooking and longer wait times.
“Most clinicians are not aware that every medical device that we have is, to a certain degree, biased,” Celi said. “They don’t work well across all groups because we prototype them and we optimize them on, typically, college-age, white, male students. They were not optimized for an ICU patient who is 80 years old and has all these comorbidities, so why is there an expectation that the numbers they represent are objective ground truths?”
The exposure of deep biases in legacy systems presents an opportunity to get things right, Celi said. Accordingly, more researchers are pushing to ensure that clinical trials enroll diverse populations from geographically diverse locations.
One example is Beth Israel’s MIMIC database, which reflects the hospital’s diverse patient population. The tool, overseen by Celi, offers investigators de-identified electronic medical records — notes, images, test results — in an open-source format. It has been used in 10,000 studies by researchers all around the world and is set to expand to 14 additional hospitals, he said.
Age of agility
As in the clinic, AI models used in the lab aren’t perfect, but they are opening pathways that hold promise to greatly accelerate scientific progress.
“They provide instant insights at the atomic scale for some molecules that are still not accessible experimentally or that would take a tremendous amount of time and effort to generate,” said Marinka Zitnik, an associate professor of biomedical informatics at the Medical School. “These models provide in-silico predictions that are accurate, that scientists can then build upon and leverage in their scientific work. That, to me, just hints at this incredible moment that we are in.”
”What is becoming increasingly important is to develop reliable, faithful benchmarks or techniques that allow us to evaluate how well the outputs of AI models behave in the real world.”
Marinka Zitnik
Zitnik’s lab recently introduced Procyon, an AI model aimed at closing knowledge gaps around protein structures and their biological roles.
Until recently, it has been difficult for scientists to understand a protein’s shape — how the long molecules fold and twist onto themselves in three dimensions. This is important because the twists and turns expose portions of the molecule and hide others, making those sites easier or harder for other molecules to interact with, which affects the molecule’s chemical properties.
Marinka Zitnik, assistant professor of biomedical informatics
“Insights from research labs don’t always translate into effective treatments, and AI could amplify this gap if it’s not designed to bridge it.”
MARINKA ZITNIK: I am most excited about AI’s ability to learn and innovate on its own, instead of just analyzing existing knowledge. AI can generate new ideas, uncover hidden patterns, and propose solutions that humans might not consider. In biomedical research and drug development, this means AI could design new molecules, predict how these molecules interact with biological systems, and match treatments to patients with greater accuracy. By integrating information across genetics, proteins, all the way to clinical outcomes, AI can speed up discoveries in ways that was previously not possible. A major challenge, however, is that AI models tend to focus on problems that have already been extensively studied, while other important areas receive less attention. If we are not careful, medical advances may become concentrated in familiar areas, while other conditions remain under-explored, not because they are less important, but because there is less existing knowledge to guide AI systems. Another issue is that AI-driven drug design and treatment recommendations often rely on experimental findings generated in research labs that might not fully capture the complexity of real patients. Insights from research labs don’t always translate into effective treatments, and AI could amplify this gap if it’s not designed to bridge it. The opportunity is to build AI that makes discoveries and ensure that those discoveries lead to meaningful advances, bringing innovation to areas where it’s needed most.
Today, predicting a protein’s shape — down to nearly every atom — from its known sequence of amino acids is feasible, Zitnik said. The major challenge is linking those structures to their functions and phenotypes across various biological settings and diseases. About 20 percent of human proteins have poorly defined functions, and an overwhelming share of research — 95 percent — is devoted to just 5,000 well-studied proteins.
“We are addressing this gap by connecting molecular sequences and structures with functional annotations to predict protein phenotypes, helping move the field closer to being able to in-silico predict functions for each protein,” Zitnik said.
A long-term goal for AI in the lab is the development of “AI scientists” that function as research assistants, with access to the entire body of scientific literature, the ability to integrate that knowledge with experimental results, and the capacity to suggest next steps. These systems could evolve into true collaborators, Zitnik said, noting that some models have already generated simple hypotheses. Her lab used Procyon, for example, to identify domains in the maltase glucoamylase protein that bind miglitol, a drug used to treat Type 2 diabetes. In another project, the team showed that Procyon could functionally annotate poorly characterized proteins implicated in Parkinson’s disease. The tool’s broad range of capabilities is possible because it was trained on massive experimental data sets and the entire scientific literature, resources far exceeding what humans can read and analyze, Zitnik said.
The classroom comes before the lab, and the AI dynamic of flexibility, innovation, and constant learning is also being applied to education. The Medical School has introduced a course dealing with AI in healthcare; added a Ph.D. track on AI in medicine; is planning a “tutor bot” to provide supplemental material beyond lectures; and is developing a virtual patient on which students can practice before their first nerve-wracking encounter with the real thing. Meanwhile, Rodman is leading a steering group on the use of generative AI in medical education.
These initiatives are a good start, he said. Still, the rapid evolution of AI technology makes it difficult to prepare students for careers that will span 30 years.
“The Harvard view, which is my view as well, is that we can give people the basics, but we just have to encourage agility and prepare people for a future that changes rapidly,” Rodman said. “Probably the best thing we can do is prepare people to expect the unexpected.”
Nation & World
How WWI vets shaped Civil Rights Movement
Study traces surge in activism among Black men who faced discrimination while defending country
Christina Pazzanese
Harvard Staff Writer
March 20, 2025
4 min read
Soldiers of the 92nd Infantry Division take part in a victory parade on 5th Avenue in New York City following World War I.European/FPG/Getty Images
Black men drafted i
Study traces surge in activism among Black men who faced discrimination while defending country
Christina Pazzanese
Harvard Staff Writer
4 min read
Soldiers of the 92nd Infantry Division take part in a victory parade on 5th Avenue in New York City following World War I.
European/FPG/Getty Images
Black men drafted into the U.S. Army during World War I were significantly more likely to join the NAACP and to play key leadership roles in the early Civil Rights Movement as a result of the discrimination they experienced while serving the country, according to a new study by Harvard Kennedy School economist Desmond Ang and Sahil Chinoy, a doctoral student in economics.
Looking to measure what drove the postwar boost in political activism among Black veterans, the researchers combed through millions of military records, U.S. Census data, as well as membership rolls for the National Association for the Advancement of Colored People in the decade following the war. They found that by 1930, World War I veterans comprised 15 percent of male members of the NAACP, the leading civil rights organization of the period.
The significant discrimination Black troops faced while serving in the Great War — working in segregated units with little formal training — “seeded deep feelings of institutional betrayal and discontent” that compelled many veterans to challenge the status quo after 1918, Ang and Chinoy concluded.
Desmond Ang (left) and Sahil Chinoy.
Photo by Grace DuVal
Black men who were induced to enlist were three times more likely to join the NAACP, the study found. Since the early 1800s, Black Americans had been barred from serving in the military and attending institutions such as West Point and the U.S. Naval Academy. When World War I broke out, the U.S. needed to beef up its defensive ranks quickly, so in 1917 it instituted the first nationwide draft of Black men, conscripting nearly 400,000. The move was unpopular, particularly within the all-white armed forces, and Black and white servicemen were segregated. Nearly 90 percent of Black troops were assigned labor-intensive or menial jobs, say the researchers, and most were denied combat and officer training, firearms, and promotions.
Soldiers who were most caught off guard by the hostile treatment they received were the likeliest to become politically active, the study found. For example, researchers traced the highest NAACP enrollment to veterans of the 92nd Division, who risked their lives in combat while facing constant racial abuse. The study saw lower enrollment among noncombatants and veterans of the 93rd Division, who experienced less discriminatory treatment while brigading overseas with the French military.
Identifying the private motivations of veterans from a century ago was difficult, so to help understand how Black soldiers felt about the war, Ang and Chinoy reviewed questionnaires administered by state commissions asking veterans to describe their service and how it affected them. Those who served in camps that denied training or promotion opportunities were more than twice as likely to cite injustice in their survey responses.
Another rich source of information, said Ang, were contemporaneous reports assembled by U.S. military intelligence, which had a department monitoring what it called “Negro subversion.” White officers would go from camp to camp taking the temperature of Black troops. The two greatest causes of discontent cited by Black service members in the reports were the dearth of promotion opportunities while laboring under often cruel and unqualified white supervisors, and the lack of military training in return for their service.
“The government had a really good handle on what things were really upsetting Black people,” which “speaks to this idea that a lot of this was very deliberate, institutional decisions that were happening,” said Ang. “It really seems to corroborate this narrative [historian] Chad Williams and others have talked about, which is the sense of hypocrisy and injustice that was going on.”
Ang and Chinoy say the research may “underestimate” how influential World War I veterans were in terms of the potential spillover effects on their families, friends, and others in the Black community, a subject they intend to explore next. Also, the researchers are starting to look at how the backlash to the NAACP’s rise and the Civil Rights Movement sparked a rebirth of the Ku Klux Klan and Jim Crow in the 1920s.
Citing the white power movement following the Vietnam War and the paramilitary styling of some far-right groups today in the U.S., Ang wonders whether the dynamics at play during World War I is a piece of a much larger puzzle. “Is this something that we can see historically, and what are the aspects of military service” that may drive people to become politically active?
Health
Sick again? Maybe your building is to blame.
Illustrations by Liz Zonarich/Harvard Staff
March 20, 2025
1 min read
Take our quiz to learn more about how indoor air quality can impact your health
Do you ever find yourself feeling tired or struggling to concentrate while at the office? In “Healthy Buildings: How Indoor Spaces Can Make You Sick — or Keep You Well,” Harvard public health and business
Take our quiz to learn more about how indoor air quality can impact your health
Do you ever find yourself feeling tired or struggling to concentrate while at the office? In “Healthy Buildings: How Indoor Spaces Can Make You Sick — or Keep You Well,” Harvard public health and business experts Joseph Allen and John Macomber explore how the places we spend most of our time — our homes, workplaces, and schools — affect our well-being, focus, and problem-solving ability. Allen helped us develop the following quiz based on his research on indoor air quality.
Campus & Community
When creativity calls
Eight staff artists are featured in their homes, studios, and work spaces. Photos and video by Niles Singer/Harvard Staff Photographer
Niles Singer
Harvard Staff Photographer
March 20, 2025
8 min read
Harvard staff cultivate talents that flourish beyond the gates
Nearly 300 talented artists from across the University are displaying their work
Eight staff artists are featured in their homes, studios, and work spaces.
Photos and video by Niles Singer/Harvard Staff Photographer
Niles Singer
Harvard Staff Photographer
8 min read
Harvard staff cultivate talents that flourish beyond the gates
Nearly 300 talented artists from across the University are displaying their work in the annual Harvard Staff Art Show. Created as a venue where staff can share their creativity with the broader community, the show is now in its fifth year. Below are profiles of eight of these creatives who were happy to chat about their projects.
Scott Murry
Designer, Illustrator, and Photographer
Senior Designer, Harvard Library
Scott Murry in his apartment.
Scott Murry said his “Find Yourself,” part of a series of monoline-style digital drawings about mental health created during the pandemic, is about “trying to think about who you are with intentionality.”
Murry’s interest in the visual arts was nurtured in ninth and 10th grades by teachers who motivated and challenged him to achieve. He went to the Art Academy of Cincinnati and Art Institute of Boston and “was wild about editorial illustration and children’s book illustration” before taking on various roles at design agencies, in environmental design, and at the Weekly Dig.
These days Murry is being intentional with his time, drawing, designing, doing concert photography, publishing a children’s book, and working on a photo book of his son, Elliott. He is particularly excited by the design possibilities of the double Ls and double Ts in his son’s name.
Murry works on a drawing from his series that reads, “Have hope it will be better.” The drawing is “related to something from the pandemic or politics, where it just felt very busted, like, you know, you find your car on cinder blocks with a broken windshield, which I have with my own car.”
Pairs of custom Vans shoes printed with Murry’s designs.
Eve Radovsky
Cabinet and Furniture Maker
Faculty Assistant, Harvard Law School
Eve Radovsky holds the cabinet she’s displaying in this year’s Staff Art Show.
In 2018, Eve Radovsky enrolled in a full-time program in cabinet- and furniture-making. “I also have always really appreciated furniture design, and I’ve always enjoyed working with my hands,” she said. Her white-oak-and-maple piece in the show was inspired by an image of a blanket chest created by Thomas Dennis in the 17th century.
Radovsky used carving gouges to remove sections of wood for the front and small metal stamps to create the background. She also used several different types of stains to “age” the piece in a way that mimicked the more dangerous process of fuming.
She has also been a passionate knitter for the past 10-plus years and is currently working on creating a sweater for herself.
The front of her cabinet is hand-carved.
Radovsky knitting while sitting in a chair she made herself.
Yuwei Li
Drawer
Neurotechnology Engineer, The Center for Brain Science
Yuwei Li holds her drawing of Lou the budgie.
Yuwei Li likes drawing cute animals, including her budgie, Lou, who died right before Thanksgiving. For her, “drawing is a way to relax and be happy,” and the picture she chose to display is meant both to remind her of her pet and thank him for being a part of her life.
“This is actually based on a photo that I took from my cell phone … One day, he was just, like, winking at me. And then I happened to capture him winking with my camera.”
Li, shown in the Center for Brain Science’s machine shop in Harvard’s Northwest Building, uses her talents at work to design and fabricate equipment for approximately 40 different labs. Her latest after-hours project — inspired by “Star Wars” fans she met at Comic-Con in San Diego — is a 3-D print of a one-to-one scale model of R2-D2, which she hopes to mount on wheels and use to carry her tools.
Li solders a project for her work in the machine shop.
Li is assembling her 3-D R2-D2 piece by piece.
Veronica Bagnole
Embroiderer
Digital Project Manager, Harvard Graduate School of Design
Veronica Bagnole holds her current embroidery project.
For Veronica Bagnole, embroidery is a calming and historically rich artform. When she isn’t overseeing the GSD’s website and supporting a team of 100 content editors, she works on embroidery pieces that can take hundreds of hours to complete.
Bagnole’s piece shows a woman from the late 18th to early 19th century, whose likeness she created from AI images that she modified to create an outline before adding texture during the roughly 250 to 300 hours it took to embroider.
“When people come to this piece, I want them to look at it and think, ‘Who is that woman? Why did she have her portrait done?’”
Bagnole said embroidery deserves more recognition as not just a craft but a historical art form that allows her to honor and “connect with generations from the past.”
The gold chain is one of several small details Bagnole improvised.
Four pairs of 19th and early 20th century embroidery scissors from Bagnole’s collection. She calls them “beautiful little pieces of history.”
Stanislav Karachev
Dancer and Poet
Energy Performance Engineer, Harvard Medical School
Stanislav Karachev poses in the mirror he used for his poetry and dance piece “My Mirror.” A video recording of his performance is in this year’s Staff Art Show.
When Stanislav Karachev was invited to dance at a venue in New Hampshire, he knew he had to go big. He ended up creating the performance featured in this year’s art show, a mix of poetry, music, and dance he used to express his feelings during a breakup.
Karachev decided that he would incorporate a mirror and engage with the audience during the performance. “Everyone thinks, ‘Oh, you’re like, I’m doing a solo. It’s all about me.’ And it’s not. It’s about the audience and the connection between the performer or performers with the audience.”
Karachev recorded his poem and mixed his backing track with the help of a neighbor who also works at Harvard. He chose krump as the dance style because of its high energy. Karachev said he ended up impressed with where the intensity drove him: “I didn’t know I could move like that.”
The sole of an artist.
A page from Karachev’s poetry notebook.
John Buonomo
Astrophotographer
Senior Cloud Architect, Harvard University Health Services
John Buonomo in front of The Great Refractor at the Harvard College Observatory.
John Buonomo’s earliest attempts at astrophotography were in 1978. The self-taught artist said he became fascinated with his subject at 9 years old when a neighbor showed him a view of Jupiter and Saturn through his refractor. Buonomo’s first photographs using film and a manual tracking scope weren’t very successful, but the advent of digital technology “changed everything.”
These days Buonomo uses dedicated cooled astro CCD cameras, high-end optics, auto guiding, and computer-controlled scripting to create his work. Once he’s captured an image, he uses specialized software to stack multiple exposures and adjust other parameters to reveal faint structures. He calls the balance of technical skill and artistic vision “what makes astrophotography both demanding and deeply rewarding.”
Arched Rock at Goat Rock Beach in Jenner, California.
Photo Courtesy of John Buonomo
Buonomo looks through the Clark Telescope at the Harvard College Observatory.
Toru Nakanishi
Photographer and Sculptor
Exhibition Production Specialist at the Harvard Art Museums
Toru Nakanishi with several of his 3-D printed sculptures.
Toru Nakanishi’s love of photography started in college, when he began creating black-and-white photos in a darkroom. But when he no longer had access to a darkroom and couldn’t justify the cost of a digital camera, he began making images on a flatbed scanner.
This year’s show includes one of Nakanishi’s flatbed scans of ramen noodles. To create his images, Nakanishi laid the noodles on the scanner and turned off all the lights to get a black background. For other images, “I made a flatbed scanner with a glass wall on top of it. You can fill it with the water and then float the item in it and then scan it.”
This photograph shown is a piece of a much larger noodle series, one image of which is currently in the collection of the Museum of Fine Arts.
Nakanishi also sculpts in wood.
Nakanishi holds the photograph he is displaying in the Staff Art Show.
Fionnuala Gerrity
Ceramicist
Conservation Technician at Harvard Library Preservation Services
Fionnuala Gerrity.
Fionnuala Gerrity first tried ceramics as a kid, but returned to it before the pandemic by taking courses at Indigo Fire in Belmont. They were surprised by the result: “I had no idea it would grow into an entire body of work, like a side gig to my professional career.”
Today, “everything that I do is based on local forest ecosystems,” Gerrity said. Using slabs as the primary construction method, building the vessel first, and finally adding sculpted elements, Gerrity tries to depict nature as accurately as possible. During the photoshoot, they shared a finished tea set decorated with “three different moths that preferentially associate with bitter nut hickory.”
“I love the idea that they might inspire people to look a little bit more closely at what’s around them,” Gerrity said.
Nation & World
Can Europe defend itself against a nuclear-armed Russia?
Production ramps up at a German munitions factory last year in response to the war in Ukraine.Fabian Bimmer/Getty Images
Christina Pazzanese
Harvard Staff Writer
March 19, 2025
8 min read
National security expert details what’s being done, what can be done as U.S. appears to rethink decadeslong support
Many Europ
Can Europe defend itself against a nuclear-armed Russia?
Production ramps up at a German munitions factory last year in response to the war in Ukraine.
Fabian Bimmer/Getty Images
Christina Pazzanese
Harvard Staff Writer
8 min read
National security expert details what’s being done, what can be done as U.S. appears to rethink decadeslong support
Many European leaders believe they can no longer rely on the U.S. for the high level of defensive support they have counted on for decades now that President Donald Trump, a longtime critic of NATO and the European Union, has returned to office.
A distinguished veteran, Hooker served in national security roles during the Trump, George W. Bush, Bill Clinton, and George H.W. Bush administrations and had been on the faculty of National Defense University, National War College, and U.S. Military Academy at West Point.
You recently wrote that Europe has to shore up its own defense because it is no longer a priority for the U.S. How do things look at this moment?
I think for sure the threat to European security is much greater. The reason is the perception that the U.S. is disengaging and, in some ways, working with Russian President Vladimir Putin. That encourages Putin and dismays the Europeans, which has a downside and an upside.
The U.S. has worked for decades to suppress any notions of European strategic autonomy. We always thought we’d be the primary security provider in Europe, and we like being the leaders of NATO. So to that extent there’s been very halting progress at developing a separate or independent capability in Europe.
There’s an article in The Wall Street Journal that argues that Europe’s got way more in the way of forces and in wealth than Russia. But when you really peel the onion back, there are a lot of problems with that thesis.
The first is that readiness across Europe is quite low, even among the major powers — the French, the British, the Germans, the Italians. They would struggle to put a single army combat division in the field in less than 60 or 90 days. They probably could not put a second in the field for much longer after that.
The U.K. had 66 divisions in World War I, it would struggle to put one out in 90 days to defend the Baltic states. So that’s a pretty low level of readiness.
Why isn’t it more robust?
The militaries across Europe have gotten much, much smaller. In the last 30 years, they’ve gone to volunteer militaries, which are much more expensive, and you can’t generate reserves with volunteer militaries. And we’ve seen from Ukraine that modern warfare, no surprise, causes a lot of casualties and consumes a lot of resources. So that’s a problem.
But the real problem is what we call the enablers. It is all the below-the-line capabilities that enable you to actually fight. This is logistics, air defense, medical support, artillery at the corps level — those kinds of things. You just don’t find those in Europe.
And so, it’s really hard to put a force together that could deter or stand up to the Russian Federation in a major war because those capabilities are either absent or very much attenuated.
Now, the overarching issue for everything is, if the U.S. disengages and withdraws its nuclear umbrella, there’s really no answer in Europe for that. There just isn’t.
That would put the European nations, and particularly those in the east, under great, great pressure, because Putin would threaten to use tactical nuclear weapons, and there’s nothing to deter that. There’s no response other than the U.S. umbrella. And there are those who argue, even now, in practice, de facto, that umbrella’s been withdrawn.
“If the U.S. disengages and withdraws its nuclear umbrella, there’s really no answer in Europe for that.”
Is Europe correct to worry the U.S. nuclear umbrella has been withdrawn?
Has it been withdrawn already? I don’t know. Is it reliable? I wouldn’t think so.
If Putin were to threaten or actually use tactical nuclear weapons in Ukraine or, let’s say in Estonia, would the administration respond with nuclear threats of its own? Personally, I have my doubts. I worked in the first 18 months of the Trump administration. I was the senior NATO guy, which is not a comfortable job to have, and I have my doubts. I’ll just leave it at that.
What are Europe’s biggest defensive shortcomings, ones that hurt its strategic autonomy?
No. 1, of course, is the nuclear question.
No. 2 is they don’t really have higher level formations. They have a lot of corps headquarters, but they’re not real corps headquarters. They don’t have the artillery, the air defense, the engineers, all that stuff that you need to fight at the corps level.
No. 3 is the readiness of the formations they do have is quite low, so they can’t push out meaningful forces in 14 days the way the U.S. can.
It’s very easy to think of Europe as one entity, but it’s really not. It’s 44 different polities, and they all see the world a little bit differently.
The eastern flank countries, they all see the world the same. The Poles, the Baltic states, the Nordics, they all border Russia. They’re spending a lot of money; they’re going back to conscription; they’re getting better every day. They see the world the way it really is. All the other nations, not so much.
Do you think European leaders are genuinely motivated to take action?
I think it’s underway. I really do. But it’s not the kind of thing that you can solve overnight.
One clear sign is that defense spending continues to rise in many places. Not in every place in Europe — there are still some key states that don’t even make 2 percent. But the big ones have all said, “We’re going to work toward 3 percent,” and their budgets do seem to be rising.
Collectively, the Europeans hit the 2 percent target in 2024, and they have been increasing spending quite a bit over the last four or five years, but it hasn’t translated yet into actual capability.
So many people, even experts, just repeat this mantra that “the Europeans aren’t spending enough.” Actually, they spend more than four times more on defense than Russia does. Russia spent about $125 billion — as far as we can tell — in 2024, and the European allies spent about $500 billion, which is a lot.
So, I don’t see spending as the issue. How that money is spent is the real issue.
Which countries have nuclear weapons and might others decide to acquire some in light of the changing landscape?
The British have about 400 deployable warheads. These are essentially strategic warheads. They have three ballistic missile submarines.
The French have about the same number deployed in about the same way. Those can threaten the 10 largest Russian cities. Those are strategic weapons; they’re not intended to try to take out Russian missile silos.
The Russians have more than 10 times that many warheads. Are those deterrents effective for those countries? I think probably yes. Could they, or would they, extend their nuclear umbrella to neighbor states or to allies? I’m doubtful about that.
There’s been discussion in Germany about generating a nuclear capability, but it seems clear the Germans are not going to do that.
It wouldn’t surprise me if the Poles might be looking at that. The Ukrainians, who do have a lot of advanced technology and used to have nuclear weapons, it’s possible the Ukrainians might think about developing some kind of nuclear capability. Outside of those cases, I just don’t see it.
Are there any steps Europe can take immediately to defend itself?
No. 1: They can return to conscription because that enables you to grow your forces quickly and generate reserves.
No. 2: It’s really hard to move forces across Europe. This problem is called military mobility. Every time you cross a national boundary, or even a provincial boundary, you get stopped. There’s a paperwork check. The rail gauges are not uniform across Europe, so you might get as far as Poland and then you have to unload everything and put it on a different train. So military mobility is a real issue.
No. 3: Interoperability, which means can we all work together on the battlefield, is a real challenge.
All the Allies can’t talk on the battlefield securely to each other, and they can’t pass data securely on the battlefield because they have different systems.
And No. 4 is just be ready. You’ve got to be serious about the problem and attack it. I do think they’re getting more serious. The question is how fast can they do it, and is there going to be more Russian aggression on European territory before they get there?
Arts & Culture
He was walking in Washington and just like that he was gone
Tony Horwitz and Geraldine Brooks in their Martha’s Vineyard home in 2016.Photo by Elizabeth Cecil
March 19, 2025
8 min read
Geraldine Brooks traces painful, disorienting pendulum-swing of grief after losing Tony Horwitz, her husband of 35 years
Excerpted from “Memorial Days” by Geraldine Brooks, Radcliffe Fellow ’06, visiti
He was walking in Washington and just like that he was gone
Tony Horwitz and Geraldine Brooks in their Martha’s Vineyard home in 2016.
Photo by Elizabeth Cecil
8 min read
Geraldine Brooks traces painful, disorienting pendulum-swing of grief after losing Tony Horwitz, her husband of 35 years
Excerpted from “Memorial Days” by Geraldine Brooks, Radcliffe Fellow ’06, visiting lecturer ’21, published by Viking, an imprint of Penguin Publishing Group, a division of Penguin Random House LLC.
May 27, 2019 West Tisbury
“Is this the home of Tony Horwitz?”
Yes
“Who am I speaking to?”
This is his wife
That is exact. The rest is a blur.
“Collapsed in the street … tried to resuscitate at the scene … brought to the hospital … couldn’t revive him.”
And, so, now he’s in the OR. And, so, now we’ve admitted him for a procedure. And, so, now we’re keeping him for observation.
So many things that logically should have followed.
But she says none of these things. Instead, the illogical thing: He’s dead.
No.
Not Tony. Not him. Not my husband out on the road energetically promoting his new book. My husband with the toned body of a six-day-a-week gym rat. The 60-year-old who still wears clothes the same size as the day I met him in his twenties. My husband, younger than I am — hilarious, bursting with vitality. He’s way too busy living. He cannot possibly be dead.
The resident’s voice is flat, exhausted. She is impatient with me as I ask her to repeat what she has just said. It is, she tells me, the end of her shift. She gives me a number for the doctor who is coming on duty in this ER, 500 miles away in Washington, D.C. She can’t get me off the phone fast enough.
But Tony — I need to see him. Where will he be when I get there?
“We can’t keep a body in the ER. It will be moved to the hospital morgue to be picked up by the DC medical examiner.”
It. A body. She means Tony.
So how will I see him? I’m in Massachusetts, on an island. It’s going to take me hours to get there —
She cuts me off.
“The DC police will need to talk to you. Make sure they can reach you.”
And then she is gone.
At some moment in this call, I stood up from my desk. When the phone rang, at 18 minutes past one, I’d only just sat down to work after a morning of distractions. I’d had a happy conversation on the phone with my older son, a recent college graduate, adventuring around the world and about to board a plane in Manila for the eight-hour flight to Sydney, where he would stay with my sister. A friend, Susanna, had come to borrow or return a book — I can’t recall which. We’d gone down to the paddock to throw hay to the horses and hung around there, draped on the split rails, chatting.
I’d read a long email from Tony about the visit he’d made the day before to the Virginia village where we lived for 10 years. It was mostly unpunctuated, gossipy, catching me up on the doings of our former neighbors — their tribulations with dry wells and divorces (“she refers to him as her was-band”). The email concluded:
“didn’t wish self back there (if for no other reason, 90 degrees and 100 percent humidity, and still May) but heartened that it seems to have gently evolved while keeping history and quirk. tomorrow back to the grind and am now 2-3 episodes behind on “Billions” so you’ll have rewatch upon return. love and hugs”
I’d hit send on my reply and finally opened the file titled Horse, the novel I was supposed to be writing.
Then, the phone.
Another distraction. I considered letting it go to voicemail.
But maybe there was a question my older son had forgotten to ask. My younger son was away at boarding school, sitting for his end-of-year exams. Perhaps he needed something. I had to pick up.
The caller ID was hard to read in the bright sunlight. Only as I brought the handset close could I make out gw hsp on the display. Don’t tell me I picked up a darn fundraising call. …
Now the dial tone burred. I stared at the handset. My legs started to shake. But I couldn’t sit down. I paced across the room, feeling the howl forming in my chest. I needed to scream, weep, throw myself on the floor, rend my garments, tear my hair.
But I couldn’t allow myself to do any of those things. Because I had to do so many other things.
I stood there and suppressed that howl. Because I was alone, and no one could help me. And if I let go, if I fell, I might not be able to get back up.
In books and movies no one gets this news alone. Someone comes to the door. Someone makes sure you’re sitting down, offers you water, asks whom you’d like them to call.
But no one had done me this kindness. A tired young doctor had picked up my husband’s cell phone, on which he had never set up a passcode, and hit the speed dial for home.
The first brutality in what I would learn is a brutal, broken system.
February 23 Essendon
The small prop plane takes off from Melbourne’s Essendon Airport. Suburban rooftops, container terminals, the industrialized mouth of the Yarra River. And then we pierce a flat layer of cloud and the view I’d hoped for, the glittering, island-studded Bass Strait, is obscured. All I can do is watch the mesmerizing blur of the propeller. A smear of concentric circles. The unlikely physics of flight.
I am headed to a shack on the farthest end of Flinders Island to do the unfinished work of grieving. I have come to realize that what I did that day in late May 2019 and what I was obliged to do in the days and months that followed has exacted an invisible price. I am going to this remote island to pay it.
In the confines of the small plane I overhear snatches of conversation from my fellow travelers:
“I’ve got a hundred acres, it’s quite a big bit of dirt.”
“No one’s prolly fished that spot since we were there last year.”
“You can have the views, or you can have the bars, but you gotta consider the cell tower if you’re building a place.”
“All the pines are gone.”
“What d’ya mean, gone?”
“I mean gone, mate. Not there.”
Tony died on Memorial Day, the American holiday that falls on the last Monday in May and honors the war dead.
When I get to Flinders Island, I will begin my own memorial days. I am taking something that our culture has stopped freely giving: the right to grieve. To shut out the world and its demands. To remember my love and to feel the immensity of his loss. “Grief is praise,” writes Martín Prechtel in his book “The Smell of Rain on Dust,” “because it is the natural way love honors what it misses.”
I haven’t honored Tony enough, because I have not permitted myself the time and space for a grief deep enough to reflect our love.
This will be, finally, the time when I will not have to prepare a face for the faces that I meet. The place where I will not have to pretend that things are normal and that I am okay. Because it has been more than three years and, contrary to appearances, I am not at all okay. I have come to realize that my life since Tony’s death has been one endless, exhausting performance. I have cast myself in a role: woman being normal. I’ve moved around in public acting out a series of convincing scenes: PTO mum, conservation commissioner, author on tour. But nothing has been normal. Here, finally, the long-running show goes on hiatus.
I have been trapped in the maytzar, the narrow place of the Hebrew scriptures. In the Psalms, the singer cries out to God from the narrow place and is answered from the “wideness” of God. Our English word “anguish” means the same thing as the Hebrew maytzar. It is from the Latin for narrowness, strait, restriction. I have not allowed myself the wild wideness of an elaborate, florid, demonstrative grief. Instead, it has been this long feeling of constriction, of holding it in and tamping it down and not letting it show.
I am not a deist. No god will answer my cries. The wideness I seek is in nature, in quiet, in time.
And I have chosen this place, this island, deliberately. Before I met Tony, my life had begun directing me here. Falling in love with him derailed that life, set me on an entirely different course. Now I might glimpse what I have been missing, walk that untraveled road, consider the person I might have become.
Alone on this island at the ends of the earth, maybe, I will finally be able to break out of the maytzar. But first I will need to get back to that moment in my sunlit study when I refused to allow myself to howl.
That howl has become the beast in the basement of my heart. I need to find a way to set it free.
Nation & World
At India Climate Conference, Harvard’s South Asia ties take center stage
Tarun Khanna. Stephanie Mitchell/Harvard Staff Photographer
Jacob Sweet
Harvard Staff Writer
March 19, 2025
4 min read
Global summit on adaptation and resilience highlights the Mittal Center’s collaborative focus
When asked in 2010 to lead what would become the Lakshmi Mittal and Family South Asia
At India Climate Conference, Harvard’s South Asia ties take center stage
Tarun Khanna.
Stephanie Mitchell/Harvard Staff Photographer
Jacob Sweet
Harvard Staff Writer
4 min read
Global summit on adaptation and resilience highlights the Mittal Center’s collaborative focus
When asked in 2010 to lead what would become the Lakshmi Mittal and Family South Asia Institute, Tarun Khanna, the Jorge Paulo Lemann Professor at Harvard Business School, proposed two guiding rules. One: He wanted the organization to be open to all fields of inquiry. And two: He wanted “feet on the street” across South Asia.
This week’s climate adaptation conference, “India 2047: Building a Climate-Resilient Future,” co-hosted by the Mittal Institute and the Salata Institute for Climate and Sustainability alongside the Indian government, is a sign of Khanna’s push for a strong, multidisciplinary connection between the University and the region, as more than 160 scholars and experts from Harvard and across the world gather to address adaptation to climate change in India.
The conference is part of the institute’s ongoing climate change initiative focused on South Asia. Since 2023, when the Mittal Institute led its first climate-related workshop in New Delhi, it has been investing in more climate-change adaptation research. Among other projects, its Community Heat Adaptation and Treatment Strategies project, funded initially by the Salata Institute, has studied the health effects of extreme heat on workers using sensors that the subjects wear throughout the day. The study will create one of the largest data sets relating to heat and health anywhere in the world.
The leaders of that research — epidemiologist Caroline Buckee and associate professor in emergency medicine Satchit Balsari — will attend the India conference and participate in workshops over several days in New Delhi, as well as a multiday “climate immersion experience” for senior faculty and analysts in Ahmedabad, the site of some of the Mittal Institute’s initial measurement work on heat stress. Among other topics, the group will address links between extreme heat and poverty, food security, rural incomes, and environmental degradation.
This multipronged approach — with collaborators from Harvard and with the Indian government’s Ministry of Environment, Forest, and Climate Change and its public policy think tank NITI Aayog — is typical of the Mittal Institute’s appetite for diverse collaborators and areas of research.
Among many projects in recent years, the institute has facilitated joint bioscience and biotechnology research between Boston and Bangalore through its Building Bharat-Boston Biosciences program; supported studies analyzing pigments in historical Indian art; and brought together researchers from the U.S., England, Bangladesh, India, and Pakistan to study the consequences of the 1947 partition of British India. From the beginning, Khanna said, the institute has tried to equally support intellectual endeavors across the sciences, social sciences, and humanities.
It has also stayed true to Khanna’s desire for “feet on the street.” The institute has built up a physical presence across South Asia, with offices in New Delhi and Lahore and representation in other countries — each of which raises project money from the countries in which they’re located. “For us to be operating with any degree of credibility, any degree of welcome in a foreign country, people better start thinking of you as embracing their societies as opposed to being an outsider,” said Khanna.
The relationships will be on display at the conference, where Harvard faculty such as Sturgis Hooper Professor of Geology Daniel Schrag, Vice Provost for Climate and Sustainability James Stock, and Professor of Earth and Planetary Sciences Peter Huybers will work with colleagues across Harvard’s Schools of business, medicine, and public health and with several agencies of the Indian government. “We have enormous goodwill,” Khanna said. “Especially at a time when higher ed is treated with skepticism, it’s a pristine asset.”
As the event unfolds, one of the largest organized by Harvard outside of the U.S., Khanna believes it’s just the beginning for the Mittal Institute — with many years of collaboration and innovation to come.
Work & Economy
Where next for U.S. economy?
Richard Drew/AP
Christina Pazzanese
Harvard Staff Writer
March 18, 2025
6 min read
Kennedy School analyst’s recession warning includes worries about trade war, stock market, risk perception
U.S. markets this month suffered heavy losses after China, Mexico, and Canada responded to President Donald Trump’s tariff push by imposing levies on Am
Kennedy School analyst’s recession warning includes worries about trade war, stock market, risk perception
U.S. markets this month suffered heavy losses after China, Mexico, and Canada responded to President Donald Trump’s tariff push by imposing levies on American goods. Many investors fear a prolonged trade war could push the nation into a recession. (The president says that Americans should expect a “period of transition.”) Meanwhile, the University of Michigan’s consumer sentiment index has fallen to its lowest level since November 2022.
These developments serve as a backdrop for meetings this week where the Federal Reserve will weigh whether to resume interest rate cuts.
In this edited conversation, economist Jeffrey Frankel, James W. Harpel Professor of Capital Formation and Growth at Harvard Kennedy School, discusses the impact of the new administration’s tariff policy and the broader condition of the U.S. economy.
Jeffrey Frankel.
Harvard file photo
Is there a good argument for increasing or expanding tariffs?
They’re pretty universally bad — almost all economists are opposed to them. Can there ever be a good justification for a tariff? Three cases I can think of. First, a poor country may have no effective way of collecting revenue other than a tariff. Second, there’s a so-called “infant industry” argument — that if government is able to identify an industry that has potential for economies of scale and spillover effects, they need to protect it against international competition for a few years and then the industry will grow, and the government will be able to remove the tariffs and have it compete on world markets. Third, the Europeans have something called CBAM, Carbon Border Adjustment Mechanism, in the cause of fighting climate change. One might interpret that as a tariff, but my interpretation is that because it helps carry out the Paris Accord, it may be beneficial and indeed is the sort of measure that is fine under the World Trade Organization. There are probably other examples, but none that apply to the U.S. today.
Treasury Secretary Scott Bessent called the market selloff a “normal” and “healthy correction” to years of overreliance on government spending, predicting that we’ll end up with a stronger economy. Is that a plausible explanation?
It’s not based on anything. Their way of coping is to stall for time, saying, “Well, of course, we’re going to have some negative effects at first, but this prosperity will come after.” But that’s not based on any kind of economic argument that I have heard, let alone a valid one.
I suppose someone could argue that with tariff protection, our manufacturing sector will achieve higher investment and higher productivity growth, and we’ll be more competitive in the long run, and that higher growth will show up in higher incomes. But the Trump approach to tariffs is hurting investment, not helping it. Usually what they say is that boosts confidence, but the current policy chaos is having the opposite effect. It’s reducing confidence.
For countries undergoing debt crises, mainly developing countries, a common pattern is that they’ve been running budget deficits that are too large, and their debt level is getting too high. Then, as part of an adjustment program, usually under the guidance of the IMF [International Monetary Fund], they have to undergo a combination of reducing the budget deficit, monetary discipline, and devaluation. That causes a year or two of severe economic pain but allows a recovery subsequently and a restoration of growth in the long-term. You could characterize Korea in ’98 that way, for example. The excessive debt part of the pattern does describe the U.S. now, but I don’t think the rest applies to the U.S. A debt crisis is not to be recommended and is not what the tariff proponents have in mind.
The latest University of Michigan consumer sentiment index shows economic confidence is at its lowest since November 2022. Also, hiring has cooled. Do these developments point to a recession or something like 1970s-style stagflation?
I think it is appropriate to worry about a recession coming within the next year. It’s much more likely than one would have thought a year ago.
I see five things going on that could logically lead to or worsen a recession. One is the trade war. The second is a stock market crash. The third is major cuts in government spending, assuming Musk and Trump manage to find genuine cuts. The fourth is a U.S. fiscal crisis because of a government shutdown, failure to raise the debt ceiling, or a downgrading by Moody’s, the credit rating agency. The fifth is a general increase in perceptions of risk. Risk is increasing because what Trump has done on tariffs and on government spending has been so erratic. It’s almost as if they’re doing everything they can to increase perceptions of variability and volatility and unpredictability. The uncertainty itself has a negative effect.
The instability has alarmed not just investors, but also sectors like real estate and health care, with many businesses shifting into “wait and see” mode. What are the implications for the wider economy?
If the uncertainty only lasted a minute, it wouldn’t have much effect, but it’s clearly going to last longer than that. Even if it takes a few months to resolve these issues, that could be enough to hurt employment and income and even to cause a recession. In the extreme, if all hiring stops for a month or two, that itself would cause a recession.
The Federal Reserve faces two seemingly contradictory options on interest rates: support the economy and jobs with rate cuts or leave them alone to keep inflation and inflation expectations under control. What’s the Fed likely do?
That’s the tradeoff. In a sense, it’s always the tradeoff, but it becomes much more acute at a time like this, because tariffs and general chaos are adverse supply shocks. They’re like a world oil shock or a COVID shock or something like that. Supply shocks make a tradeoff between output and inflation worse, and they’re not something the central bank can make up for. So, the Fed is worried both about increasing inflation and about a slowdown in the economy. One objective says keep interest rates higher, and the other says cut them. I think they will leave them unchanged.
Arts & Culture
How to read like a translator
Damion Searls. Veasey Conway/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
March 18, 2025
6 min read
Damion Searls ’92 talks process, sentence structure, and what makes a chair a chair
When someone asks Damion Searls how he “chooses” words for a translation, he likens it to asking a reader how they “choose” what Mr. Darcy
Damion Searls ’92 talks process, sentence structure, and what makes a chair a chair
When someone asks Damion Searls how he “chooses” words for a translation, he likens it to asking a reader how they “choose” what Mr. Darcy looks like when reading “Pride and Prejudice.” Neither is so much a choice, he says, but a response shaped by the text.
“We’re not translating the words that are there. We’re having a reading experience, and then we’re giving a version of that that someone who reads English can then have,” Searls ’92 told the audience that recently packed the Barker Center’s Plimpton Room to hear the acclaimed translator. “This is why there are no perfect translations or ‘right’ or ‘wrong’ translations, just like there’s no wrong way that Mr. Darcy looks.”
Searls, who works from German, Norwegian, French, and Dutch, has translated Nobel Prize winner Jon Fosse, Proust, Rilke, Nietzsche, Thomas Mann, and Max Weber. He discussed his philosophy, which he outlines in his 2024 book, at a lecture co-hosted by the Department of Comparative Literature, the Department of Philosophy, and the Mahindra Humanities Center’s Rethinking Translation Seminar.
The day before, Searls led a translation workshop with three Ph.D. students from the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences in Comparative Literature’s Secondary Field in Translation Studies.
“Whatever you think translating is, it’s some kind of reading and some kind of writing joined together,” the former Adams and Dunster House resident said. “Reading explains a lot about translation, and if you unpack what reading is you’re going to get most of the way to the philosophy of translation.”
“Reading explains a lot about translation, and if you unpack what reading is you’re going to get most of the way to the philosophy of translation.”
Damion Searls
Searls said translation isn’t that different from other forms of writing in English, which require the same skills. However what distinguishes translation is the way translators read, a close reading that engages deeply with a language’s structure.
When “reading like a translator,” Searls said he must identify which linguistic elements can be omitted in English and which are intentional stylistic choices by the author. When translating Uwe Johnson’s “Anniversaries,” for example, he noticed frequent “not this but that” constructions (“the train leaves at not 7:00 but 6:00”), which are more common in German than in English.
While it would be easy to rephrase for smoother English, he realized Johnson used this pattern deliberately to express a personal vision and “slowly hone in on the truth.”
“We can’t just erase it because it’s not just the German language: It’s him, the author,” Searls said. “Every writer is using the resources of their language to do what they want to do, and as translators we have to do the same thing with an entirely different body of resources.”
In “The Philosophy of Translation,” Searls draws from French philosopher Maurice Merleau-Ponty’s ideas about perception to describe how translating happens, arguing the “living bond” that exists between people and objects also exists between translators and the language they are reading.
Just as a person immediately recognizes a chair, understands its purpose, and is prompted to sit by the object’s existence, Searls told the audience, translators also immediately recognize written language when they read it, understand one of its purposes is to be translated, and are prompted by the language to produce the translation.
Searls also described his process when approaching a new translation, which is usually to do a slow and precise first draft, which allows him to revise later versions without referring too much to the source material. He’ll sometimes read the book beforehand, but more frequently translates as he goes.
“It feels intuitive. I just keep revising it and trying to make it sound good,” Searls explained. “As much as you can avoid looking back at the original will help you direct your attention to: Does this sound like it should sound in English?”
“It feels intuitive. I just keep revising it and trying to make it sound good.”
Damion Searls
One key to a smooth translation is keeping associations similar for readers in both languages, Searls said. While translating Fosse’s “Septology I-VII,” he encountered a reference to Gula Tidend (literally “Gula Times,”) a now-defunct newspaper published in a small town outside the city where the main character lives.
When Searls asked Fosse about the name, he learned that “gula” is an old verb meaning strong wind, and also referred to a medieval Norwegian region, the birthplace of the oldest body of laws in the Nordic countries. Fosse left the choice up to him, so Searls settled on “The Northern Herald,” which evokes medieval heraldry and the northern wind.
Most importantly, he said, his translation avoids disrupting the sentence’s flow by making English readers pause to wonder about the words in the title.
“It seems like this example of the translator being really subjective, but from my point of view, I was just reading,” Searls said. “At first, when I read Gula Tidend I didn’t know how to read it. I didn’t understand what it was doing in the book, why it was there, how it fit together. Then I looked up the words, talked to the author, and got to the point where I could read it. Once I got there, I was totally faithful.”
An audience member asked Searls how to reach the point of feeling like a skilled enough reader to translate. He responded that while some believe mastering the source language is necessary for translation, he sees more nuance. Though he knows Norwegian well enough to translate Fosse, he said, he wouldn’t necessarily feel comfortable translating just any Norwegian book.
“It’s also true that there are different kinds of expertise in the world. You don’t want to err so far in that direction that you become a sort of gatekeeper, saying that until you have a Ph.D. you’re not allowed to translate a book, because maybe you bring other things to the table,” Searls said. “It seems like a very good example of do your best and try to get better.”
Health
Is sugar addictive?
March 18, 2025
3 min read
Cravings are real, nutrition researcher says — but here’s why lumping sweets with alcohol, nicotine is a problem
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
Frank Hu is the Chair of the Department of Nutrition and the Fredrick J. Stare Professor of Nu
A series of random questions answered by Harvard experts.
Frank Hu is the Chair of the Department of Nutrition and the Fredrick J. Stare Professor of Nutrition and Epidemiology at Harvard T.H. Chan School of Public Health.
This is a heavily debated topic. Alcohol, nicotine, and opiates are all classified as addictive substances based on strict clinical criteria, and although sugar has been shown to increase cravings and compulsive eating behaviors, technically it’s not classified as an addictive substance based on current clinical criteria.
But the physical and psychological effects are real. Our food system is loaded with ultra-processed foods that contain not just added sugar but unhealthy fats and sodium. Those kinds of foods increase your cravings, because they’re very palatable, and they’re accessible. That leads to habitual consumption, and when you suddenly stop consuming those foods, you do experience some withdrawal-like symptoms: headaches, dizziness, anxiety, and so on. But it’s a matter of the degree: For alcohol, nicotine, and drugs, those symptoms are very severe, and it’s very difficult for people to completely stop consuming those substances.
We need some sweetness in our diets and in our lives.
So we can say that sugar has some addictive qualities, but it’s not officially classified as an addictive substance like alcohol, nicotine, or drugs.
It’s also important to make a distinction between a food or nutrient that we need to survive versus a drug or substance which can be completely removed from our diet. You can eliminate alcohol or drugs, but sugar is in fruits, vegetables, whole grains, milk, and other dairy products. If you consume low to moderate amounts of sugar, it’s not going to have major health consequences or psychological effects. The most important issue is the dose.
In the U.S. currently, the average person consumes almost 20 teaspoons a day of added sugar in things like sugary beverages, snacks, and sweets, which is enormous — it’s almost 300 calories. The recommendation from the American Heart Association is no more than 9 teaspoons of added sugar for men, 6 teaspoons for women, and much less for children.
People should be aware of the amount of sugar they’re consuming. Read the food labels for your cookies and snacks. Going cold turkey can backfire, so reduce your amount of added sugar gradually.
It’s difficult to classify sugar the same way as truly addictive substances. An appropriate amount of sugar in our diet can enhance flavor and texture; it can increase pleasure. We need some sweetness in our diets and in our lives. So if you classify sugar the same way as nicotine, it may be counterproductive.
Illustration by Liz Zonarich/Harvard Staff
Arts & Culture
Science? Yes. Fiction? Maybe.
Sci-fi books recommended by faculty, staff probe AI, humanity, censorship
Sy Boles
Harvard Staff Writer
March 17, 2025
6 min read
When the future feels overwhelming, some of us stock up on canned goods while others turn to books. Science fiction has long challenged how we think about technology and
Sci-fi books recommended by faculty, staff probe AI, humanity, censorship
Sy Boles
Harvard Staff Writer
6 min read
When the future feels overwhelming, some of us stock up on canned goods while others turn to books. Science fiction has long challenged how we think about technology and society, often serving as a warning about where we are going or as an inspiration to build new worlds. The Gazette asked Harvard faculty and staff from across the disciplines to give us their recommendations.
Karen Brennan
Timothy E. Wirth Professor of Practice in Learning Technologies; Faculty Affiliate, Computer Science, Harvard Paulson School of Engineering and Applied Sciences; Faculty Co-Chair, Learning Design, Innovation, and Technology
‘Blindsight’
Peter Watts
“Like many people, I’m thinking a lot about artificial intelligence,” said Brennan, who directs Harvard’s Creative Computing Lab. Brennan recommended “Blindsight,” which follows a crew of augmented humans encountering alien intelligence that seems to lack self-awareness but surpasses humans in capability.
“Through the account of the crew’s increasingly disturbing interactions with the aliens, Watts invites us to confront the uncomfortable possibility that consciousness — an aspect of human intelligence that feels so essential — might actually be an evolutionary aberration, a glitch that more powerful forms of intelligence would lack, beneficially. In this time when we’re trying to make machines more like our own minds, the book’s message feels especially urgent: Perhaps we should be less concerned about artificial intelligence becoming more like us, and more concerned about what it means if it doesn’t need to be.”
Theo Anthony
Radcliffe Institute Mildred Londa Weisman Fellow and Radcliffe-Film Study Center Fellow
‘Solaris’
Stanislaw Lem
Artist and filmmaker Theo Anthony recommended the 1961 Polish novel “Solaris.”
“A team of scientists travels to the oceanic planet of Solaris, whose waters display potential signs of intelligence. Scientific interventions fail; attempts to communicate come back as staticky echoes. Meanwhile, ghosts of dead lovers haunt the crew. ‘Solaris’ is a novel about encounters at the limits of understanding — a welcome dose of humility in the face of the unknown.”
Amy Deschenes
Head of UX & Digital Accessibility at Harvard Library
‘A Rover’s Story’
Jasmine Warga
Deschenes read “A Rover’s Story,” a middle-grade novel about the journey of a fictional Mars rover, to her 7-year-old. In the story, a rover named Res, short for Resilience, communicates with humans only in code, but is fascinated by humans’ emotions and experiences.
“My son and I chatted about why some people might feel like a machine is their friend or even their child. One of the hazmats (aka humans), Rania, is fully committed to her work, but we know from letters that her daughter writes to Res that Rania is missing out on time with her family in order to make Res’ mission a success. Rania, one of the more pragmatic hazmats, unexpectedly shares a song with Res before he leaves for his mission. She tells him that she hopes he will remember her and that the song will bring him luck. This shift in her behavior, revealing that she does have an emotional connection to Res, was another point my son and I discussed. We speculated that maybe she is missing her daughter and trying to connect with Res in a more meaningful way because of this.
“As AI continues to evolve in ways I can’t even imagine, this gave my son and I the opportunity to reflect on what makes us human. It led us to discuss how machines might act as surrogates for friendship, and why they will never replace true human connections. ‘A Rover’s Story’ invites us to embrace our unique human traits, even as AI and machines become a significant part of our lives.”
Ursula Friedman
College Fellow in Contemporary Chinese/Taiwanese/Sinophone and Latin American Literature, Translation Studies, Comparative/World Literature, Media and Sound Studies
‘Exorcism’
Han Song
Much of novelist Han Song’s science fiction has been censored by the Chinese government for being “too dark,” but for Friedman, that’s part of what makes his work so great.
“The universe has been diagnosed with an incurable disease and has begun to mutate, alternately waxing poetic and killing off patients, in a last-ditch attempt to cure itself,” Friedman says. “Yang Wei awakens to find himself relegated to a geriatric ward aboard the Peace Ark, a military-ward-turned-hospital-ship governed by robots and AI beings. The ship’s operations are overseen by a glitching AI being known as Siming, whose vacillating policies clash with those of the hospital authorities.”
“‘Exorcism’ certainly feels like an instruction manual for averting disaster in today’s world, in the sense that Siming manufactures and dramatizes disaster. In the novel, the key to averting catastrophe lies in recognizing that although the universe may explode at any moment, human beings can create their own narrative culture by questioning the authorities’ version of reality and choosing pain over cultural amnesia. The ‘narrative-implant therapy’ in the novel strikes me as hauntingly similar to much of the political rhetoric spun by the U.S. media. In the novel, the hospital system alters the warp and weft of time and space, just as the current political regime attempts to skew our perception of ‘reality.’ The colorful characters aboard the Peace Ark grow inured to their own insurmountable pain as war and death rage around them. Their anesthetized bodies become war zones upon which industrial progresses clash with the impulse to forget and destroy.”
Jeff Saviano
Business AI Ethics Leader at the Edmond & Lily Safra Center for Ethics
‘Fahrenheit 451’
Ray Bradbury
Saviano, an AI ethicist, recommended Bradbury’s classic cautionary tale about censorship, saying it serves as an enduring reminder about power and control of information.
“In the novel, books are outlawed, and access to knowledge is systematically erased — not just through brute force, but through a culture of distraction and passive consumption,” he said. “People in Bradbury’s novel are pacified by immersive entertainment, which diminishes their curiosity and critical thinking. It’s not just about what’s banned; it’s about what replaces it.
“This theme is particularly urgent in the new age of AI, where algorithm-driven content curation shapes what we read, watch, and even believe. Just as Bradbury’s world suppresses books in favor of shallow entertainment, today’s AI systems can amplify mindless digital engagement at the expense of deep thought and critical thinking. ‘Fahrenheit 451’ reminds us that protecting intellectual freedom requires more than just keeping books on shelves — it demands vigilance against technology that prioritizes instant gratification over meaningful understanding. A must-read for anyone thinking about AI’s role in shaping the future of knowledge.”
Campus & Community
Harvard expands financial aid
New effort ensures that more undergraduates, especially from middle-income families, will receive support
March 17, 2025
3 min read
File photo by Stephanie Mitchell/Harvard Staff Photographer
Harvard University President Alan M. Garber and Edgerley Family Dean of the Faculty of Arts and Sciences Hopi Hoekstra on Monday announced that Harvard College wi
New effort ensures that more undergraduates, especially from middle-income families, will receive support
3 min read
File photo by Stephanie Mitchell/Harvard Staff Photographer
Harvard University President Alan M. Garber and Edgerley Family Dean of the Faculty of Arts and Sciences Hopi Hoekstra on Monday announced that Harvard College will be free for students from families with annual incomes of $100,000 or less and tuition-free for students from families with annual incomes of $200,000 or less. This significant expansion of financial aid, which begins in the 2025-26 academic year, will make Harvard affordable to more students than ever, especially from middle-income families.
“Putting Harvard within financial reach for more individuals widens the array of backgrounds, experiences, and perspectives that all of our students encounter, fostering their intellectual and personal growth,” Garber said. “By bringing people of outstanding promise together to learn with and from one another, we truly realize the tremendous potential of the University.”
The expansion will enable approximately 86 percent of U.S. families to qualify for Harvard College’s financial aid, extending the University’s commitment to providing all undergrads the resources they need to enroll and graduate.
“Harvard has long sought to open our doors to the most talented students, no matter their financial circumstances,” said Hoekstra. “This investment in financial aid aims to make a Harvard College education possible for every admitted student, so they can pursue their academic passions and positively impact our future.”
Starting in the 2025-26 academic year, Harvard College will be free for students whose family income is $100,000 and below. This covers all billed expenses including tuition, food, housing, health insurance, and travel costs. Additionally, each of these students will receive a $2,000 start-up grant in their first year and a $2,000 launch grant during their junior year to help support the transition beyond Harvard.
Students with family incomes of $200,000 or less will receive free tuition and additional financial aid to cover billed expenses, depending on their financial circumstances. And many students with family incomes above $200,000 will also receive aid, depending on their circumstances. Harvard’s financial aid staff work personally and individually with students and families to match each family’s specific situation.
“We know the most talented students come from different socioeconomic backgrounds and experiences, from every state and around the globe,” said William R. Fitzsimmons, Harvard College’s dean of admissions and financial aid. “Our financial aid is critical to ensuring that these students know Harvard College is a place where they can be part of a vibrant learning community strengthened by their presence and participation.”
The expansion builds on more than two decades of investment in undergraduate financial aid at Harvard, beginning in 2004 with the launch of the Harvard Financial Aid Initiative, which completely covered tuition, food, and housing costs for students from families with annual incomes of $40,000 or less. This threshold has increased four times since then — from $60,000 in 2006 to $85,000 in 2023.
In 2007, Harvard eliminated loans, providing all assistance in the form of grants. It also eliminated home equity in determining a family’s ability to pay for College.
Harvard has awarded more than $3.6 billion in undergraduate financial aid since launching the Harvard Financial Aid Initiative. Harvard College’s annual financial aid award budget is $275 million for academic year 2025-26. Fifty-five percent of undergraduates currently receive financial aid. Their families paid an average of $15,700 for the 2023-24 year.
“Our team works closely with each student to ensure full inclusion in the Harvard experience,” said Griffin Director of Financial Aid Jake Kaufmann. “The financial aid program is designed so that Harvard students can study, train, research, create, and fully engage in the Harvard experience with minimal constraints.”
Robert Putnam, author of the influential 1995 book “Bowling Alone,” spoke at the JFK Forum.Photo by Martha Stewart
Nation & World
Want a less divisive America? Just a matter of trust.
Robert Putnam traces nation’s plummeting social connection and rocketing discord, offers way to start thinking of solution
Clea Simon
Harvard Correspondent
March 14, 2025
6 min read
America is coming apa
Want a less divisive America? Just a matter of trust.
Robert Putnam traces nation’s plummeting social connection and rocketing discord, offers way to start thinking of solution
Clea Simon
Harvard Correspondent
6 min read
America is coming apart, warns Robert Putnam. It’s all due to a growing lack of social connection, and it’s visible in our relationships, communities, and deeply riven politics.
The bottom line is that we just don’t trust each other anymore, he said. But there are places to start.
The Peter and Isabel Malkin Professor of Public Policy, Emeritus and author of the influential 1995 book “Bowling Alone” spoke at a John F. Kennedy Forum in a March 12 conversation with former Kennedy School Dean David Ellwood, the Isabelle and Scott Black Professor of Political Economy, Emeritus.
Putnam began with a discussion of national politics. He noted that President Trump’s critics blame him for our problems.
“America is in deep trouble,” said the 84-year-old political scientist. But Trump, he explained, didn’t create the turmoil. “He’s a symptom.”
“The real threat of what’s happening right now in America is not what’s on the surface, but the fact that the underlying causes of that are still there,” said Putnam. “And they will still be there when Trump is long gone unless we do something about it.”
That, said Putnam, is because our isolation — our lack of social capital — is growing worse, particularly among people with less education. “What the election showed is that the people, and above all the working class in America, were isolated. That’s why Trump won,” he said.
Putnam spoke a bit about his latest book, “The Upswing,” co-authored with his former student Shaylyn Romney Garrett. He drilled down on the data about what he called “political polarization, economic inequality, social isolation, and cultural self-centeredness.”
Putnam showed a series of graphs, all of which described a rough bell curve, starting low, peaking, and then coming back down. All of them, he explained, covered the period from roughly 1890 to 2020 in the U.S.
The first measured “political comity or bipartisanship,” which hit its high during the presidency of Dwight D. Eisenhower, “the most bipartisan — or nonpartisan — president in our history.” While that chart continued its high through John F. Kennedy’s presidency, its decline has been steady since.
“Now is probably the most politically polarized period in American history, with the exception of a period between 1860 and 1865.” He paused to make sure the room understood why he chose those dates. “That’s how close we are to a civil war,” he said.
The next chart, with a very similar curve, graphed economic equality, which has once again reached such a low level that it rivals the 1890s Gilded Age. A graph of social cohesion followed that same curve.
“Americans were very socially isolated at the beginning of the 20th century.” During that period of industrialization and urbanization, he said, “Large numbers of people were moving from villages in Sicily or villages in Iowa to the big city,” leaving their families and community connections behind. “And they had not yet made new ones.”
But they would.
“You see coming out of the ’30s and up until the ’60s, Americas were becoming much more trusting of one another,” he said.
“It’s not just about economics. Two-thirds of American society are not just unhappy about the fact that they don’t have good income or great chances of upward mobility. ”
Robert Putnam
Describing his own college experience in the ’60s, he recalled, “Most Americans trusted one another. Seventy-five, maybe 80 percent of Americans said they trusted other people,” Putnam said. “I think the latest number I saw was 10 percent of Americans say they trusted other people. And it’s still going down. We’ve still not stopped declining in our sense of connection with one another.”
The roots of these declines have many causes. The first is our definition of community — who is the “we” that makes up America. “The ‘we’ that we built over the course of the first two-thirds of the 20th century was a shriveled ‘we,’” said Putnam. “It was not just a white male ‘we,’ but it was more white than nonwhite” as well as more male than female.
“If we have a new progressive era, it has to have a more capacious sense of ‘we,’” he said.
We are also now isolated by social class, with the biggest gap being between those with college educations and those without. “The people who are left behind are the non-college-educated part of America.
“Only one-third of America has a college degree,” he said. “Do the math. We are never going to win unless we can begin to connect with the less-educated parts of America.”
Framing the issue as not an economic issue but a moral one, Putnam brought up Hillary Clinton’s ill-phrased dismissal of the “deplorables” who supported Trump.
“It’s not just about economics. Two-thirds of American society are not just unhappy about the fact that they don’t have good income or great chances of upward mobility. They don’t think we respect them — and we don’t,” Putnam said, referring to the college-educated, mostly middle-class or higher professional, corporate, and managerial class.
What we have to do is connect, he advised. Rebuild those social networks that allowed Americans to interact across class and education lines. And while many tout in-person connections, Putnam said, “It’s a mistake to think we have to have either face-to-face or virtual connections. Most of our connections are alloys, partially face-to-face and partly virtual.”
Such connections can help us bond in ways not connected with politics. He then gave a very local example: “I happen to be a Red Sox fan,” he said. “If you want to build connections among people from different parts of Boston or different age groups or different genders, bond in Fenway Park.
“Bridging in one direction, often depends on bonding in some other dimension,” he noted.
Ultimately, he said, “It is absolutely crucial that this new movement be based on youth. There are cultural things that young people of any class can bond on, like memes, and bridge other directions.
“I’m not giving you an answer,” he said. “I’m giving you a strategy for approaching an answer.”
Arts & Culture
‘The Odyssey’ is having a moment. Again.
The enduring appeal of the “The Odyssey” can be seen in the A.R.T.’s production; a new translation by Daniel Mendelsohn; and a forthcoming movie from director Christopher Nolan (pictured).Photos by Nile Scott Studio and Maggie Hall; Andreas Rentz/Getty Images
Liz Mineo
Harvard Staff Writer
March 14, 2025
5 min read
Classicist Greg Nagy
The enduring appeal of the “The Odyssey” can be seen in the A.R.T.’s production; a new translation by Daniel Mendelsohn; and a forthcoming movie from director Christopher Nolan (pictured).
Photos by Nile Scott Studio and Maggie Hall; Andreas Rentz/Getty Images
Liz Mineo
Harvard Staff Writer
5 min read
Classicist Greg Nagy on story’s epic appeal, his favorite translation, and ‘journey of the soul’ that awaits new readers
Homer’s “Odyssey” has captured people’s imaginations for nearly 3,000 years. Testaments to its enduring appeal abound: A recent stage adaptation of the epic poem at the American Repertory Theater; a movie by Oscar-winning director Christopher Nolan is in the works; and a new translation by Bard scholar Daniel Mendelsohn will be published next month.
In this edited interview, Greg Nagy, Francis Jones Professor of Classical Greek Literature and Professor of Comparative Literature, reveals his favorite of the more than 100 translations of the poem, explains the appeal of the “trickster” Odysseus, and more.
What can you tell us about Homer?
There is nothing historical about the person called Homer. However, there’s everything historical about how people who listened to Homeric poetry imagined the poet. Homeric poetry evolved especially in two phases. The earlier phase was in coastal Asia Minor, in territory that now belongs to the modern state of Turkey and in outlying islands that now belong to the modern state of Greece. In these areas, around the late eighth and early seventh centuries B.C.E., there was a confederation of 12 Greek Ionian cities, which is where “The Iliad” and “The Odyssey” evolved into the general shape that we have. A second phase took place in preclassical and classical Athens, around the sixth and fifth centuries B.C.E. Before such a later phase, almost anything that was epic could be attributed to this mythologized figure called Homer.
Gregory Nagy.
Niles Singer/Harvard Staff Photographer
There have been more than 100 translations of the poem. Do you have a favorite?
I like the translation by George Chapman, a poet in his own right, who published the first complete translation of “The Odyssey” into English in 1616. There is that famous poem by John Keats (1816), in which he speaks about reading Chapman’s Homer. I also like the translation by Emily Wilson, who was the first female translator of “The Odyssey” (2017) into English.
I also like the translations by Richmond Lattimore and Robert Fitzgerald, both of whom were dear friends. Lattimore was probably one of the most accurate translators of Homeric poetry; he cared about the original Greek text as it was eventually transmitted. He is easy on the eye, but hard on the ear. Fitzgerald is easier on the ear. And then there is Robert Fagles (1996), who has done the most actor-friendly translation.
I like Wilson’s translation very much. She is a great poet; she has a real ear for what’s going on in the minds and hearts of the characters. One of my favorite parts is how Wilson handles the gruesome death of the handmaidens who are not loyal to the household of Odysseus, and their agonizing death is so beautifully treated without any false sympathy.
Novelist Samuel Butler, who was a real romantic of the Victorian sort, wrote the book “The Authoress of ‘The Odyssey,’” where he imagines that the poem is composed not by Homer, but by Homer’s daughter. For her masterful translation, I would say that Wilson could be considered as the daughter of Homer.
Why do we find Odysseus fascinating? He’s cunning, vengeful, and so flawed …
I learned when I was a graduate student at Harvard from my professor, John H. Finley, that Odysseus, whom we all see as an epic hero, gets “a bad press” almost everywhere except in “The Odyssey.” Odysseus is what anthropologists call a trickster — a hero who is not originally an epic hero, but someone who, by way of knowing all the norms of society, can violate every rule, whether it’s a deeply ingrained moral law or whether it’s a matter of etiquette, as in the case of table manners. The value of the trickster is that it teaches us what the rules are because the trickster will show you how every one of them can be violated.
“The value of the trickster is that it teaches us what the rules are because the trickster will show you how every one of them can be violated.”
What we read in the very first line of “The Odyssey” summarizes it: “The man, sing him to me, O Muse, that man of twists and turns …” What can be more fascinating than somebody who has unlimited capacity to shift identities?
Who is your favorite character? Odysseus? Penelope? Telemachus?
Penelope is my favorite character in “The Odyssey” because she’s so smart. I have written a commentary interpreting the dream of Penelope that she narrates to her husband, who is still in disguise. If my interpretation is right, then the deftness of her narration shows that she is even smarter than Odysseus!
Finally, what should readers learn from the poem?
In the Homeric “Odyssey,” the hero experiences a journey of the soul. Reading the epic can lead to the reader’s own journey.
Timi Esan ’27 (left) and Ted Nash are pictured during rehearsal. “One of the takeaways from the couple of days for me was kind of more about the personal interaction with the students than it was even about the music.”Photos by Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Getting into the swing of things
Dylan Goodman ’25
Harvard Correspondent
March 14, 2025
3 min read
Stud
Timi Esan ’27 (left) and Ted Nash are pictured during rehearsal. “One of the takeaways from the couple of days for me was kind of more about the personal interaction with the students than it was even about the music.”
Photos by Stephanie Mitchell/Harvard Staff Photographer
Students plan concert with saxophonist and composer Ted Nash that ends with enlightening dinner conversation
At Arrow Street Arts, the Harvard Jazz Orchestra found itself swinging with Grammy-winning saxophonist and composer Ted Nash. The Feb. 21 sold-out concert, which I planned alongside Emil Massad ’25, marked an exciting collaboration with Jazz at Lincoln Center.
The center was eager to collaborate with Harvard because, as Todd Stoll, its vice president of education, noted, “Harvard is such a revered institution worldwide. It is important that people also realize that the arts play a very vital role in the lives of students.”
For this performance, Nash arranged the pieces he played with the orchestra, immersing us in his creativity.
“Ted approached the music with wisdom and attention to detail through the energy and emotion he brought, and the insightful comments, suggestions, and anecdotes he shared,” said saxophonist Zeb Jewell-Alibhai ’27.
After rehearsal, we had dinner with Nash, giving us a chance to connect beyond playing. He talked of growing up in a musical family and always knowing he wanted to be a musician.
“He encouraged us to reflect on our own histories as a way of developing creativity, walking us through how his family and past experiences shaped his music,” making the opportunity to play his arrangements even more meaningful, said Massad.
For Nash, dinner was the highlight. “It was unusual because the students were so bright and open and willing to talk about things that are important to them — that moved me,” he said.
Nash talked to us about our interests and fears, offering insight and encouragement. He was surprised that most students were not music concentrators, noting, “They had so many other things they wanted to talk about … that actually overlapped with music.”
“Collaborating with Ted Nash was effortless. Ted created an ideal environment with amazing energy, resulting in a successful concert,” said Yosvany Terry, Harvard director of jazz bands and a senior lecturer on music.
Director Yosvany Terry (left) conducts.
Zeb Jewell-Alibhai ’27 solos on tenor saxophone.
Ted Nash (left) and drummer Dylan Goodman ’25 speak during rehearsal.
Raghav Mehrotra ’26 plays drums during rehearsal. Trumpet player Christopher Shin ’27 performs during the concert.
Harvard Medical School Ph.D. candidate Ed Hutton plays his trombone.
Alto saxophonist Matthew Chen ’26 (right) solos during the concert.
Nash shares, “I felt that a number of the kids in that band played at a professional level, and yet they understand the difficulties of choosing a life of music, and that’s part of their intelligence as well.”Ted Nash (right) solos on soprano saxophone.
The audience gives a standing ovation following the performance.
A musician carries his music case, freshly signed by Ted Nash.
Health
U.S. innovation ecosystem is envy of world. Here’s how it got started.
During World War II, government-supported research led scientists to successfully mass produce penicillin. Here workers at a United States Department of Agriculture research lab, ca. 1943, look for mold strains that produce the highest amounts of the antibiotic. USDA file photo
Alvin Powell
Harvard Staff Writer
March 14, 2025
9 min re
U.S. innovation ecosystem is envy of world. Here’s how it got started.
During World War II, government-supported research led scientists to successfully mass produce penicillin. Here workers at a United States Department of Agriculture research lab, ca. 1943, look for mold strains that produce the highest amounts of the antibiotic.
USDA file photo
Alvin Powell
Harvard Staff Writer
9 min read
Economist who studies technological change looks at public-private research partnership amid rising questions on federal funding
The participation of the federal government in the nation’s innovation ecosystem has been under scrutiny lately. For decades, federal funds have supported academic research, which in turn, has boosted private development, fueling new discoveries in medicine, technology, and other fields. The Trump administration is seeking to cap reimbursement for indirect research costs for biomedical science, which could mean billions of dollars in funding cuts from the National Institutes of Health.
The issue has turned a spotlight on the nation’s public-private research partnership, which has been credited with advances in a wide array of fields and emulated around the world. The Gazette spoke with Daniel P. Gross, an associate professor of business administration at Duke University’s Fuqua School of Business and former professor at Harvard Business School. Gross, together with Bhaven Sampat from Arizona State University, authored a recent National Bureau of Economic Researchworking paper on the postwar expansion of biomedicine.
In this edited conversation, Gross said the partnership was a response to the urgent demands of World War II, helped the U.S. and its allies win the war, and seeded the current thriving system.
What is your view of this partnership between the federal government and academia and how did it get started?
That partnership has been in place essentially since World War II. Its roots trace back to June 1940, when a handful of leaders at U.S. universities and industrial R&D labs approached President Franklin D. Roosevelt to propose harnessing civilian scientists to develop new technology for the U.S. military, which at the time significantly lagged on the technological frontier of warfare.
This was over a year before the U.S. entered the war, but it marked the beginning of an undertaking that engaged tens of thousands of scientists at firms and universities in the war effort, yielding numerous breakthroughs then, and was subsequently extended and deepened throughout the Cold War and has continued growing since. This partnership has been a pillar of U.S. technological leadership over the past 80 years, in biomedicine and beyond.
At the time, the National Institutes of Health existed, but it was a shadow of its current self?
The U.S. innovation system, and particularly the biomedical innovation system, looked very different in 1940.
The three pillars of U.S. biomedicine today are universities, the life sciences industry, and the NIH. Today they work together and build on each other. But in the 1930s, they were far more primitive. Universities were less research-intensive and had very little funding. The pharmaceutical industry wasn’t well organized, and to a large degree consisted of chemical companies with a minor subsidiary drug business rather than the large, dedicated drug developers we know today.
Drug discovery then was driven more by trial and error empiricism than science — drugs weren’t even subject to FDA review for safety until 1938 and efficacy until 1962. And the NIH was small and only intramural — it was not yet providing extramural research funding like we have now.
“In nearly every war before World War II, infectious disease killed more soldiers than battlefield injuries. Suddenly, there was an urgent need for innovation with immediate practical payoff — but no real infrastructure for getting it done.”
And that was seen as inadequate once the war began?
The war posed a wide range of technological problems, from detecting enemy aircraft to keeping soldiers healthy. In nearly every war before World War II, infectious disease killed more soldiers than battlefield injuries. Suddenly, there was an urgent need for innovation with immediate practical payoff — but no real infrastructure for getting it done.
The war provided an impetus for organizational innovation to support technological innovation. This included a new agency to coordinate and fund wartime research, the Office of Scientific Research and Development, or OSRD. It also triggered the invention of the federal R&D contract, new patent policies, peer review procedures, and even indirect cost funding.
Most importantly, however, was the embrace of the idea that R&D investment was an activity for the federal government, and a new pattern of collaboration between the government, firms, and universities.
Was it largely successful? Penicillin is a story that’s mentioned quite a bit.
Most would say yes. After all, the Allies won the war — and technology, medical and otherwise, was an important contributor to that outcome. New drugs are not necessarily the first thing you think of when you imagine military technology. Yet disease and other ailments could debilitate the military’s field forces, increasing required manpower. Tuberculosis, measles, and venereal diseases are all examples of common maladies among soldiers at the time. Malaria was prevalent in the Pacific theater and North Africa.
The broad range of fronts where this global war was fought, and new weapons with which it was fought, certainly expanded the set of problems needing attention — included protecting soldiers from extreme environmental conditions like hot and cold temperatures or oxygen deprivation at high altitudes, disease vector-control strategies, wound and burn treatments, blood substitutes, and much more.
OSRD’s Committee on Medical Research (CMR) directed and funded hundreds of projects on these problems and made significant progress in many of them. You’re right that one of the more important and remembered breakthroughs was penicillin. Though penicillin was discovered in the 1920s, at the dawn of World War II there was no method of producing penicillin in enough quantities even for clinical testing, let alone treatment.
CMR initially set out with two approaches to developing penicillin as a drug, not knowing which would succeed. One was to try synthesize it. The other was to try to grow it in large quantities from the mold that produces it. Scientists initially thought that the synthetic approach held more promise, but in the end it was scaled-up fermentation of natural penicillin that succeeded.
This breakthrough was transformative — not only for military health but civilian health too. The proof is in the data: Between World War I and World War II, military hospital admissions and death rates from most common infectious diseases declined by 90 to 100 percent. World War II research essentially solved the military’s problem of bacterial disease.
Perhaps even more important is that it spawned a golden age in drug development. The antibiotic revolution of the 1950s and 1960s can be directly traced to achievements in the war.
Some things became successful in the postwar period. Why did this effort have such long legs?
Across the CMR portfolio, the work undertaken to meet the urgent demands of war created a foundation upon which postwar biomedical science and technology subsequently began to grow. That foundation consisted of things like new research tools and techniques, new therapies and therapeutic candidates, new drug development platforms, newly developed capabilities at existing and emerging pharmaceutical firms — including experience in specific drug categories and more generally in science-based approaches to drug discovery, like rational drug design — and most importantly, new scientific understanding.
What abouttraining a new generation of scientists?
It’s a great question. Many readers might think that public R&D funding primarily supports research. But scientific training is also important. The war effort engaged not only seasoned scientists but also thousands of graduate students, predoctoral researchers, and recently minted Ph.D.s. This was the case for both medical and nonmedical research: The labs doing the work were teeming with young people. Although we don’t trace the contributions of these students in biomedicine, I think it’s safe to presume that for many, it was formative.
In related work with Maria Roche, an assistant professor and former colleague at HBS, we have shown this was the case for researchers engaged in World War II radar research. More broadly, when you look at university and policy leadership across U.S. science in the first 25 years after World War II, you see OSRD alumni all over the place. The war proved to be a breeding ground for technical and administrative capacity that the U.S. harnessed afterwards.
When you talk about CMR funding, it included reimbursement for indirect costs — a subject of debate today. What was the rationale behind that then?
It’s useful to think about the context: OSRD needed to incentivize firms and universities to take on military R&D projects. Doing so required reorienting existing research efforts and displacing future ones — this was disruptive. Firms were being asked to use their own facilities, equipment, and sometimes best talent on national problems rather than commercial ones. Some were reluctant to do so without complete compensation. Medical researchers were also initially wary of public funding and bureaucratic control.
Reimbursing these R&D performers for overhead expenses, in addition to the immediate incremental costs of OSRD-contracted work, was one way it incentivized participation. Ultimately, the policy goal was for OSRD research to be “no gain, no loss” for its contractors. The structure of and motivations for indirect cost recovery have evolved somewhat since then, but the basic principles trace back to it.
Today it’s a bit different, in that we’re not building something, but we are trying to continue something that has proven to be successful?
It appears it’s been pretty productive. I wouldn’t dispute that there are opportunities to make the system more efficient, but overall, if you look at the output of this 80-year partnership between U.S. universities, federal research funders, and industry, it’s a story of success. I think we ought to be careful that, in pursuing reforms in science policy, we protect the golden goose.
The U.S. innovation system, and especially the biomedical innovation system, is the envy of the world. It has catalyzed decades of innovation that have supported national defense, health, and economic growth. To undo that would be a great loss for the U.S. and the world.
Arts & Culture
Showing that Black lives matter — everywhere
In a new book, music professor considers race in all its facets
Nikki Rojas
Harvard Staff Writer
March 14, 2025
3 min read
Jessie Cox.File photo by Stephanie Mitchell/Harvard Staff Photographer
Growing up in Switzerland, Jessie Cox found it difficult to speak about being Black. Black lives remained largely unthought of in the
In a new book, music professor considers race in all its facets
Nikki Rojas
Harvard Staff Writer
3 min read
Jessie Cox.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Growing up in Switzerland, Jessie Cox found it difficult to speak about being Black. Black lives remained largely unthought of in the tiny, land-locked nation, he believed.
Since then, he’s thought about them. In his new book, “Sounds of Black Switzerland,” Cox, an assistant professor of music who’s currently teaching an advanced course on studio collaboration, addresses the dynamics of race in a place where it is rarely discussed.
“One task for me was to open a discourse about Black Switzerland. Another task was to contribute to the thinking of Blackness and Black studies,” said Cox, a composer, drummer, and scholar from the western city of Biel.
“Sounds of Black Switzerland,” released in February as Cox dove into his second semester at Harvard, fuses cultural appraisal and sophisticated music criticism. Some chapters are devoted to Blackness and Afrofuturism. Another analyzes how anti-Blackness can rest on color-blindness and erasure. Cox examines the associated challenges with Switzerland’s judiciary system, immigration law, and notions of national belonging.
Yet Cox didn’t want his critique of anti-Blackness to anchor the book.
“Rather, I wanted to uncover the imaginative possibilities that we can come to think and hear under the term ‘Blackness,’” he said. “My goal was to show that there are inherent possibilities uncovered in all these discourses around Black life and Blackness in the U.S. and globally.”
Cox said he was inspired by Nigerian Swiss composer Charles Uzor, who wrote a series that includes “Bodycam Exhibit 3: George Floyd in Memoriam,” to which Cox devotes a full chapter. The 2020 murder in Minneapolis was later compared to the case of Mike Ben Peter, a Black man who died in 2018 after being pinned down by six police officers in the Swiss city of Lausanne.
Determined not to reduce the Black experience to the violence Black communities face, Cox also draws on songs by popular Swiss artists, including the Bern-based rapper Nativ.
“Nativ has this piece in which the chorus says, ‘Today is a good day for change’ in Swiss German, but the word ‘change’ is in English, so it’s a reference to Barack Obama,” Cox explained.
“To be able to think about what we are going through in our lives and our world in as many facets as we can is crucial to coming together and learning about each other’s experiences,” said Cox, who taught a fall 2024 course titled “Music to Re-imagine the World: From Afrofuturism to Experimental Music Across Planet Earth.”
“There is very radical possibility that we can get — if we invest in artistic practice as a space for imagining new worlds — new ways of being, new commonalities, and new relations,” he said.
Nation & World
Number of those burdened by rental affordability hits record high
Christina Pazzanese
Harvard Staff Writer
March 13, 2025
8 min read
Public policy expert discusses possible ways to cut costs amid national housing crunch
Amid a nationwide housing shortage, a new report shows the number of those burdened by rental affordability has hit a record high.
As of 2023, 22.6
Number of those burdened by rental affordability hits record high
Christina Pazzanese
Harvard Staff Writer
8 min read
Public policy expert discusses possible ways to cut costs amid national housing crunch
Amid a nationwide housing shortage, a new report shows the number of those burdened by rental affordability has hit a record high.
As of 2023, 22.6 million renter households spent more than 30 percent of their income on rent and utilities, up by 2.2 million since 2019. More than half, or 12.1 million, of those spent more than 50 percent of their income on housing costs, according to recent research by the Joint Center for Housing Studies at Harvard.
Worsening affordability affects renters across income groups. Middle-income renters, who earn $30,000-$75,000, comprised 41 percent of all cost burdened households in 2023. Those earning $75,000 and more were 9 percent. A full-time job is no guarantee that housing will be affordable. Indeed, 36 percent of fully employed renters were cost-burdened in 2023.
In this edited conversation, Chris Herbert, the center’s director, explains why renting continues to grow less affordable and what cities can try to do about it.
The number of households struggling with housing costs is at an historic high. What’s driving this?
There’s two things. Since 2021, we saw rents going up at double-digit rates in the immediate aftermath of the pandemic. In 2023, they started to slow down. In 2024, they were growing at more like an inflationary clip, so “better.” That was a function of very strong demand from the pandemic. Supply couldn’t keep up and led to high rents.
It came on the backs of what had been deteriorating affordability for the last two decades. There was a quiet affordability crisis growing, which is, how many renters were cost-burdened.
In the aftermath of the Great Recession, we reached a peak around 2011 in terms of both numbers and share of renters who were cost-burdened. From there, things gradually got a bit better.
But underneath the surface, while the overall share of renters who were cost-burdened was edging down, the share of renters working year-round, full-time, at not great but not terrible jobs, we were seeing a sharp increase in the share of renters who were cost-burdened.
What was happening was the cost-burdened/housing affordability issue was really being democratized. It was spreading from just among the poorest households to more working folks, particularly young people.
There was a real worsening of the crisis since the pandemic, but it had already been getting worse, and particularly worse for working people.
The number of cost-burdened renters has hit another record high
Many more middle- and higher-income renters are struggling with housing costs. What accounts for that shift?
That’s kind of the $64,000 question. The most common answer people give is that we haven’t been building enough housing. To some extent, that’s true. Multifamily vacancy rates had gotten quite tight, particularly in the face of the pandemic surge. So, there was a sense that we didn’t have enough apartments.
That is a piece of the story, but we almost overemphasize it. The other part of the story is that the cost of producing housing units is very high. There’s this notion, “Build more houses, and the price will come down.” You have to bear in mind that builders only build housing if it makes economic sense to do so.
The expense comes in four big buckets: There’s land, and that’s where a lot of the conversation has been around zoning and the fact that we don’t have enough land zoned for high-density housing. And then there’s construction costs — that’s 60 percent of the cost of an apartment building. The land, typically, is only 20 percent. And then there’s the soft costs: architectural, engineering, and then, financing. Those costs go up with a difficult approval process. They’re about 10-15 percent of the cost, so not a big driver. But the financing costs, when interest rates go up to 7 percent, is a big driver.
Housing is expensive for a host of reasons, zoning being one of them, construction costs, and the fact we haven’t had improvements in efficiency in the construction sector, and then the complexity of the approvals process and the high cost of capital.
Boston mayoral candidates Josh Kraft and Mayor Michelle Wu said housing affordability will be a top issue in the upcoming election. Do mayors and cities have any real tools to bring down housing costs?
There’s been a lot of discussion and emphasis on the regulatory processes. How restrictive is your zoning? How onerous is your approval process? How hard is it for a developer to propose a reasonable scale development and get it approved and start work on it? A big thing cities are doing is relooking at their zoning. Cambridge has done various iterations of looking at their zoning.
Related to that can be the approval process: The affordable housing overlay in Cambridge says if you put forth a development that meets criteria in terms of setbacks and density and other factors, we’re going to approve it, and you don’t have to go through a whole process of design review. So, cities can do that.
How does that affect affordability? It reduces the soft costs. To the extent you’re giving me greater density, I may be able to get a better value of land. The challenge is that the land’s value is based on how many units you can put on it. And so, if you tell me I can put two units on it, and the land was worth, say, a million bucks, and then you say, “Now you can put 10 units on it.” That’s $100,000 a unit. I just saved a ton of money.
But as soon as you tell a developer you can put 10 units on it, the developer says, “I’ll pay 5 million bucks for that piece of land.” So, you don’t get as much savings from the density. All cities can do in that regard is try to make it so there’s not more friction and more pressure on prices to go up faster than they otherwise would.
You’re going to have a hard time solving the affordability problem through zoning. And if you’re talking about lower-income households or even moderate-income households, you’re going to have to talk about ways in which you’re going to subsidize the cost of that housing. That means cities have to find ways to get money.
Boston has been very good about linkage payments for commercial development generating a fair amount of money, as has Cambridge, and an affordable housing trust that gets money from that. They can use some general appropriations from their budget.
You can also look for special taxes. Boston put forward a transfer tax proposal that former Mayor Marty Walsh estimated would generate about $100 million a year in income for the Affordable Housing Trust. Mayor Wu pursued it, but the state legislature has stymied them.
A big issue for cities is how do we get more financial resources to help subsidize housing. One of the things cities can do is go catalog all the land they own. That land can be an important subsidy. Boston’s been doing that.
“A big issue for cities is how do we get more financial resources to help subsidize housing. One of the things cities can do is go catalog all the land they own. That land can be an important subsidy. Boston’s been doing that.”
Chris Herbert
And maybe spur innovation in the design of housing. Boston’s Housing Innovation Lab has been looking at how do we get more modular housing, more efficiencies of factory production and how can the City of Boston play a role in trying to help that get to scale.
Any promising policy ideas or positive trends on the horizon?
We’re definitely in a situation where we have to try a lot of things. There’s a lot of experimentation. There’s a piece in the Mass. state bond bill for a revolving loan fund. People have come to the realization that housing affordability has been a long-term problem that’s been a long time in the making, and so we have to have a long-term vision of how we address this.
One of the big ways in which housing inflates in value is through the inflation of land values. Houses depreciate, and so, the value of a house built in 2000 should be less today. But in fact, housing values around here are double what they were in 2000, and that’s all in the land value. It’s land values that capture a lot of the inflation in house prices. And so, one thing to do is to lock in land ownership long term to keep that inflation from affecting the occupants of the home.
The other piece is that if [property owners] manage housing at cost then you can start charging rents that are a lot more affordable. Combine that with public ownership or nonprofit ownership that could be exempt or limited property taxes, low-cost land, at-cost rents, and reduced costs from reduced property taxes, you can start to get housing that is affordable.
Surrounded by Kirkland House signs, the John Harvard Statue watches over the College’s annual Housing Day tradition in Harvard Yard. Veasey Conway/Harvard Staff Photographer
Campus & Community
The House that will be home
Eileen O’Grady
Harvard Staff Writer
March 13, 2025
5 min read
Housing Day — one of Harvard’s most beloved traditions — marks a milestone for first-years
When first-
Housing Day — one of Harvard’s most beloved traditions — marks a milestone for first-years
When first-year student Wilson Cheung and his four suitemates woke up at 7 a.m. on Thursday, they could already hear upperclassmen gathering in the Yard outside their dorm. They waited excitedly in their room as the sounds drew closer until finally, around 8:30 a.m., a loud group made their way up the stairs.
When Cheung heard chants of “C-A-B-O-T,” he briefly wondered if he was about to be sorted into Cabot House, but when the door opened it was a group of Adams House residents there to greet him enthusiastically and give him his assignment letter.
As he hugged a friend in front of the John Harvard Statue 15 minutes later, Cheung couldn’t stop smiling.
“My suitemate and I got Adams and we’re super happy,” he said. “Adams just finished its renovation, so we’re going live in a brand-new dorm. It’s also close to everything, right in the center of campus. It’s a very cool dorm.”
Dunster House residents play music and dance in the Yard before storming first-year dorms.
Photo by Dylan Goodman
Housing Day, when first-year students learn where they will live for the next three years, is one of Harvard’s most beloved — and rowdy — annual traditions. Upperclassmen representing the 12 residential Houses flock to Harvard Yard early in the morning to showcase their House spirit and friendly rivalry. At 8:30 a.m., upperclassmen storm the first-year dorms to deliver housing assignment letters and welcome their newest Housemates home.
Students danced and celebrated in front of the bronze John Harvard, many in coordinated outfits, such as blue T-shirts for Lowell House and burgundy beanies for Winthrop. Some Dunster House residents walked by playing trumpets and saxophones, while Leverett House residents, wearing green bunny ears, honked green plastic stadium horns. House mascots, like the Dunster House moose, Currier House tree, and Cabot fish, danced around and posed for photos.
Winthrop House residents Ikenna Ogbogu and Ebun Oguntola, both sophomores, rallied with the rest of their Housemates, dressed in burgundy shirts. Ogbogu, who was holding a sign that read “’Throp, what a W,” said he loves Housing Day because getting his housing assignment last year was a milestone in the Harvard experience.
A Winthrop House resident cheers.
Photo by Dylan Goodman
Jeffrey Yang ’26 (center) laughs with his fellow Adams House residents.
Veasey Conway/Harvard Staff Photographer
Wearing polar bear mascot costumes Pforzheimer House residents cross Garden Street on their way to Harvard Yard.
Veasey Conway/Harvard Staff Photographer
“You’re part of a larger community with such so much more history than your freshman hall,” Ogbogu said. “Being on the other side now and being able to dorm-storm freshmen, dressing up, shouting in the morning at 7 a.m. is just really fun because you’re part of creating an experience for everyone here.”
Rakesh Khurana, Danoff Dean of Harvard College, paused to take selfies with a costumed group as he greeted students in the Yard. Khurana said the annual tradition is one of the most “incredible” experiences at the College.
“The Houses are what make Harvard College so distinctive,” Khurana said. “One of the things I love about this day is that this is when every House becomes a home for our students.”
“At a time when many of us feel like we need an injection of joy, Housing Day delivered just that,” said Hoekstra. “It’s magical to watch friendships — maybe lifelong ones — form right before your eyes.”
Outside Hollis Hall, Lowell House seniors Anoushka Chander and Una Roven, both in blue jackets, posed for a photo together while their Housemates flooded into the dorm. The seniors, who were holding a sign that read “take the L,” were feeling nostalgic to be experiencing the tradition for the last time.
“It’s just a great tradition to celebrate our House and the wonderful community that we have and each other,” Chander said. “It’s our last Housing Day to let people know they got the best House, and that it will be their home for the next few years.”
Their advice to first-years experiencing Housing Day for the first time?
“Just enjoy it,” Chander said.
“Yeah, enjoy it, any House you get will be awesome,” Roven agreed, then paused. “But Lowell is the best.”
First-year students await their House assignments as they watch the festivities below their residence hall.
Veasey Conway/Harvard Staff Photographer
Dressed as the Cabot House mascot, Max Wagner ’27 prepares to enter a first-year dorm room.
Veasey Conway/Harvard Staff Photographer
A Currier House resident waves the House flag.
Photo by Dylan Goodman
After delivering a Housing Day letter to a first-year dorm, bunny-eared Leverett House students boo Dunster House residents as they exit.
Photo by Dylan Goodman
Amelie Lima ’27 holds up a Currier House sign.
Photo by Dylan Goodman
Adams House residents wave to first-years in their dorm rooms.
Veasey Conway/Harvard Staff Photographer
Niels Korsgaard ’25 (left) of Mather House rallies atop the John Harvard Statue.
Veasey Conway/Harvard Staff Photographer
In Annenberg Hall Michael Young ’25 (from left), Naomi Whidden ’27, Emily Schwartz ’27, and Mila Ivanovska ’25 pose for a photo at the Dunster House table.
Niles Singer/Harvard Staff Photographer
Harrison Warfel ’26 of Quincy House makes himself heard over the boisterous crowd.
Veasey Conway/Harvard Staff Photographer
Lowell and Eliot House residents show their spirit.
Veasey Conway/Harvard Staff Photographer
An Eliot House resident in a mastodon costume rallies the group.
Photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
5 things we learned this week
Sy Boles
Harvard Staff Writer
March 13, 2025
1 min read
How closely have you been following the Gazette? Take our quiz to find out.
Ditching butter has a big impact. Climate change is changing the forest. The cost of homeowners insurance is screwy. Drug manufacturing costs could be lowe
How closely have you been following the Gazette? Take our quiz to find out.
Ditching butter has a big impact. Climate change is changing the forest. The cost of homeowners insurance is screwy. Drug manufacturing costs could be lower. Harvard runs (or ran) on typewriters.
Campus & Community
It’s going to get even harder to write (or at least type) like Sylvia Plath
Thomas Furrier.Photos by Stephanie Mitchell/Harvard Staff Photographer
Liz Mineo
Harvard Staff Writer
March 12, 2025
7 min read
Cambridge Typewriter, one of few shops left to buy, repair vintage machines, prepares to close doors after more than half a century
Ever since Tom Furrier announce
It’s going to get even harder to write (or at least type) like Sylvia Plath
Thomas Furrier.
Photos by Stephanie Mitchell/Harvard Staff Photographer
Liz Mineo
Harvard Staff Writer
7 min read
Cambridge Typewriter, one of few shops left to buy, repair vintage machines, prepares to close doors after more than half a century
Ever since Tom Furrier announced he was closing Cambridge Typewriter the phone has been ringing off the hook.
“I’m going out on top,” hollered the 70-year-old on a recent morning at his storefront on Massachusetts Avenue in Arlington, where he moved the business, which has been around for more than 50 years, after buying it from his old boss in 1990. “I’m busier than ever.”
Furrier’s tiny shop is a mid-century relic, with the smell of ink wafting through the door, framed period ads on the walls, and dozens of vintage manual typewriters emblazoned with names such as Underwood, Remington, Smith-Corona, and Royal perched on shelves and sitting on the floor in sturdy cases.
Like so many businesses, Furrier’s was disrupted by the digital revolution of the 1990s. But recent years have brought a modest renaissance for the 19th-century communication technology as a wave of young customers with a penchant for manual typewriters boosted the store’s finances.
This new cohort joined the shop’s shrinking group of regulars, which over the years has included celebrated writers like Pulitzer Prize-winning historian David McCullough, novelist Celeste Ng (“Little Fires Everywhere”), memoirist Susanna Kaysen (“Girl, Interrupted”), and poet Louise Glück, who won the 2020 Nobel Prize in literature — and generations of Harvard, MIT, and Boston-area students and faculty members.
Although his business is still robust, Furrier says he’s ready for retirement. Decades of lifting and fixing typewriters (about 30,000 by his count) have left him with worn cartilage in his hands and chronic back pain. After plans to sell the shop failed twice, he will shut down at the end of March.
It’s bittersweet.
“I’m really going to miss this place,” said Furrier, his work jacket showing stubborn grease stains and, in his pockets, his favorite tools: a spring hook and a small screwdriver to reach inside the machines’ nooks and crannies. “I’m going to miss my customers. My regular customers are very upset because now they’ll have to travel to southern New Hampshire, Rhode Island or southern Connecticut … But I’m just done.”
A forestry major and lifelong tinkerer, Furrier began as a typewriter technician in the 1980s, when he was 25. In those days he did mostly service calls at MIT and Harvard Law School, where he would fix machines used by scholars such as Laurence Tribe, Alan Dershowitz, and others, he said.
In recent years, others with links to Harvard have visited his shop, among them Tayari Jones, a 2011-2012 Radcliffe Fellow who became a typewriter devotee.
Jones’ encounter with Furrier was as serendipitous as it was consequential. Struggling with writer’s block, she visited the shop seeking inspiration.
“Tom made me into a convert,” said Jones, who teaches creative writing at Emory University, in a phone interview. “It wasn’t until I went to Tom’s that I discovered manual typewriters … Tom is the greatest typewriter doctor because he doesn’t run his shop like a museum. He’s not fussy and prissy about it. He’s very practical and down to earth. He wants us all just to have fun with the typewriter; just get it; put some paper in there; make some noise and make some art.”
“Tom is the greatest typewriter doctor because he doesn’t run his shop like a museum.”
Tayari Jones
Jones now writes on vintage manual typewriters. In fact, her 2018 award-winning best-seller “American Marriage” was produced entirely on a typewriter — one of the 11 in her collection, five of which she bought from Furrier.
“There’s so much pressure in the industry to be fast,” Jones said. “Using a typewriter made me feel like, I can slow down and work at my own pace … And there is something so satisfying about raising a racket when using a typewriter.”
Professors Jill Lepore and Leah Price visited Furrier’s shop as they were preparing for “How to Read a Book,” a seminar they co-taught a few years ago. The class asked students to think about the tools they use to take notes by recapitulating the history of note-taking technologies, Lepore wrote in an email. Students used clay and a stylus, paper and quills, typewriters and smartphones.
Lepore said she used the typewriters she bought from Furrier in a history class she taught in the fall.
“We visited Cambridge Typewriter some years back to stock up,” wrote Lepore. “I still use the three typewriters that I bought from him then … It’s harder and harder to find typewriters to use. When the ones I’ve got break down, or when I can no longer replace the ribbon, this crucial piece of the history of technology will be lost.”
Reached by email, Price, an associate in Harvard’s English Department and Henry Rutgers Distinguished Professor at Rutgers University, said she had sort of an epiphany at Furrier’s store.
“Visiting Tom’s shop helped me understand that coming up with ideas is the easy part,” said Price. “Repairing the tools that record and transmitting those ideas turned out to be surprisingly tricky, and banging out their thoughts on a typewriter keyboard helped slow down our students to a pace where they had to think before they wrote. Come the apocalypse, every Crimson journalist may want to know how to change a typewriter ribbon.”
“Visiting Tom’s shop helped me understand that coming up with ideas is the easy part.”
Leah Price
Visitors often come to Furrier’s shop as if it were a museum or a curiosity shop.
“If people come in by themselves, they come back with family or friends because they say, ‘You’ve got to come to see this shop,”’ Furrier said. “Or people come with their grandkids to show them that this is what they used to write with.”
Furrier said it took him by surprise when a younger crowd started appearing in the early 2000s. Some were aspiring writers who wanted to emulate legendary ones, like the customer looking to purchase a Hermes 3000, the model famously used by American poet Sylvia Plath. Others were looking for something computers can’t offer.
“To write on a typewriter is a totally different experience than writing on a computer,” said Furrier. “It’s a sensorial experience; the sounds of the click-clack, the feel of the keys and the paper, the smell of the ink. And there are no distractions. Typewriters only do one thing; you can’t multitask on it, and that’s a new thing to younger people.”
“It’s a sensorial experience; the sounds of the click-clack, the feel of the keys and the paper, the smell of the ink. And there are no distractions. Typewriters only do one thing; you can’t multitask on it, and that’s a new thing to younger people.”
Thomas Furrier
Reflecting on his career, Furrier said he most cherishes the friendships he made with writers and some customers, and a couple of stints as a typewriter consultant for period films, among them one by documentary filmmaker Errol Morris.
Other highlights include the time when actor Tom Hanks, a typewriter collector, gifted him an autographed Olympia SM4 machine with a typewritten letter asking him to “take good care of it and help it keep doing its job for another hundred years.”
And then there was being mentioned in the acknowledgment section by Jones in “American Marriage.”
To bid farewell, Furrier will hold a retirement party with typewriters for people to use on March 22 at the Fox Library in East Arlington. Longtime customers, friends, and the general public are all invited.
“It has been beyond my wildest dreams,” Furrier said of his career. “For a tinkerer like me, fixing typewriters has been fun and rewarding. I got to befriend some amazing writers and geek out about typewriters. And how many people can say they got movie credits and a book acknowledgement?”
Arts & Culture
On fiction, grief, and, most of all, ‘radical honesty’
Chimamanda Ngozi Adichie shares with readers the story behind ‘Dream Count,’ a novel she was scared she’d never finish
Anna Lamb
Harvard Staff Writer
March 12, 2025
5 min read
Chimamanda Ngozi AdichiePhotos by Veasey Conway/Harvard Staff Photographer
For Chimamanda Ngozi Adichie, fiction is a calling. Last week, the
On fiction, grief, and, most of all, ‘radical honesty’
Chimamanda Ngozi Adichie shares with readers the story behind ‘Dream Count,’ a novel she was scared she’d never finish
Anna Lamb
Harvard Staff Writer
5 min read
Chimamanda Ngozi Adichie
Photos by Veasey Conway/Harvard Staff Photographer
For Chimamanda Ngozi Adichie, fiction is a calling. Last week, the former Radcliffe fellow and 2018 Class Day speaker visited Harvard Square to mark another milestone in her vocation with the release of “Dream Count” — a book more than 10 years in the making.
The author of four novels, Adichie published her third, the critically acclaimed “Americanah,” in 2013. For a while, she worried there wouldn’t be another.
“Dream Count” is “actually quite an emotional moment for me because in some ways, I can’t believe that I’ve actually written a novel,” Adichie told a packed crowd gathered in the First Parish Church for an event sponsored by Harvard Book Store. “At some point, I wasn’t sure that I would ever write a novel again, and I was terrified. It was an unbearable thought. And so I feel this immense gratitude to be here, to have people actually come out, and hear me talk about this novel.”
“Dream Count” follows four interconnected women as they pursue love and self-discovery through hardships. The first, whose story opens the book, is Chiamaka, a Nigerian travel writer from a privileged background living in the U.S. The narrative also follows her hyper-independent cousin, Omelogor, living in Nigeria; Zikora, a Nigerian lawyer in Washington whose life isn’t quite going to plan; and Chiamaka’s Guinean housekeeper, Kadiatou, whose tragedy unites the characters.
“When it comes to fiction, the whole point of it is that you have to let go. You have to be willing to go wherever it takes you,” Adichie told the audience members who filled the church’s 600-seat meetinghouse space.
The backdrop is the pandemic, when, as Adichie puts it, “The world sort of stopped briefly, and it was so surreal and so unique, that people reacted in all kinds of ways.” Even so, the novelist had a lot more on her mind than just COVID.
The new book is “about many things,” Adichie said. “It’s about thinking about the other lives that we might have led. Sometimes, even when we’re content in our own lives, we still imagine other paths that our destiny could have taken us on. And I think it’s also about knowing about how much one knows oneself, about how much one knows other people.”
“Dream Count” was shaped in part by personal shocks that revealed hidden interior truths, Adichie said. In 2020, when her father died from complications of kidney disease, the intensity of her grief surprised her. Instead of the numbness she expected, she began weeping and pounding the floor.
“I started thinking about self-knowledge after my father died,” she said. “I found myself thinking about what love is, and one of my conclusions is that to love a person is to attempt to know them. But at the same time, I think we’re limited by how much we can, in fact, know even ourselves. The fact that we that we can surprise ourselves is just endlessly fascinating to me.”
During the Q&A portion of the event, longtime fans and new readers alike praised Adichie for her rich characters and narrative skills. Some sought advice for dealing with political uncertainty. One aspiring novelist wanted to know how to write fiction without giving too much away.
“I think you do have to give too much of yourself away,” Adichie answered. “Fiction is my vocation. I think it’s the reason I’m here … And so when I’m writing fiction, I don’t think about my audience. I really do feel as though I’m suspended in this just wonderful, magical place.”
She added: “When it comes to fiction, the whole point of it is that you have to let go. You have to be willing to go wherever it takes you. That I think, is the fundamental requirement of writing good fiction — a certain kind of truth, a certain kind of, what I like to call radical honesty.”
Adichie gave birth to her first child, a daughter, in 2016, followed by twin boys in 2024. Asked about balancing work with family life, she said, “Motherhood is the greatest lesson that I’ve had in my life, but it does come at a cost. It requires a kind of balance and things that you need to step back from for a while, and it just is the way it is. When I started to feel that I was in that horrible writer’s block space, I would make time to read poetry … I did that in service to my writing even though the writing was not happening. There are small ways in which you can still hold onto whatever it is that you want to achieve, even if you are not able to fully engage with it at the time.”
Nation & World
Johnny can read. Jane can read. But they may not fully comprehend.
Liz Mineo
Harvard Staff Writer
March 12, 2025
4 min read
Ed School panel looks at how to reverse declining scores on recent ‘Nation’s Report Card’
Educators have made significant progress in the science of reading in recent decades. Teachers know how to get students to the point where they can take on
Johnny can read. Jane can read. But they may not fully comprehend.
Liz Mineo
Harvard Staff Writer
4 min read
Ed School panel looks at how to reverse declining scores on recent ‘Nation’s Report Card’
Educators have made significant progress in the science of reading in recent decades. Teachers know how to get students to the point where they can take on simple declarative sentences. So Johnny and Jane can read — but they have trouble comprehending more complex ideas. There is still much work to do, said experts at an Ed School panel in a webinar on Thursday.
Moderated by Pamela Mason, senior lecturer on education at the Harvard Graduate School of Education, the panel highlighted the need to improve literacy outcomes in light of the latest National Assessment of Educational Progress (NAEP) — known as the “Nation’s Report Card” — which showed declines in reading scores for U.S. fourth and eighth graders.
“If you can’t read words off the page, you’re not going to understand what you read.”
Phil Capin
Assistant professor of education Phil Capin.
Niles Singer/Harvard Staff Photographer
Experts discussed the science of reading, an interdisciplinary body of research, based on the Reading Rope concept, which teachers have been using since the 2000s to help children become skilled readers, capable not only of reading words but fully comprehending what they read. According to the reading rope model, many strands are woven into skilled reading, the biggest of which are word recognition and language comprehension.
Educators have succeeded in teaching word-recognition skills, such as phonological awareness, decoding, and sight recognition, but they are missing the mark in helping children learn language-comprehension skills, such as background knowledge, vocabulary, language structures, verbal reasoning, and literacy knowledge, said professor of education James Kim. Educators need to use the reading rope model more effectively, he said.
“We know how to help kids climb easy structures,” said Kim. “We know how to help kids read familiar narrative texts like ‘The ants ate the chips at the picnic,’ but where we are struggling is in helping kids use that rope to climb very tall and very difficult structures. And you know what those structures are? They are NAEP scores.”
Phil Capin, assistant professor of education, agreed with Kim that educators could do more to help students develop comprehension skills, which are crucial to critical thinking and problem-solving. There is an array of skills and knowledge that contribute to successful reading comprehension, and they are all intertwined, he said. Early reading instruction and being able to read words are necessary, but they are insufficient for students to understand what they read. Both steps are critical.
“If you can’t read words off the page, you’re not going to understand what you read,” said Capin. “It should also be just as obvious that if you don’t understand what the individual words mean, you’re very unlikely to be able to understand the text.”
Vocabulary and background knowledge are the strongest predictors of reading comprehension, said Capin. Educators can find practice guides on how to help students build language comprehension skills at What Works Clearinghouse, an initiative of the Department of Education, he said.
“We’ve made progress in the science of reading simple text, yes. Now we need to make progress in the science of reading difficult science, math and English language arts text.”
James Kim
Professor of education James Kim.
Niles Singer/Harvard Staff Photographer
Research has found that students engaged in active and purposeful reading and collaborative learning tend to achieve the best results. “If we want students to get better at reading and understanding texts, it’s critical that teachers take a step back and allow students the opportunity to engage successfully in reading difficult texts and to make meaning together,” said Capin.
Parents can do their part to help children learn to read and understand what they read, said Kim, by reading aloud more difficult books and teaching them new words. “We have to remember that reading to learn and preparing kids to read to learn can happen from birth, basically from the time the kids are born,” he said.
If anything, the declines in fourth and eighth graders’ reading scores underscore how hard it is for children to gain effective reading comprehension skills, said Kim. As part of the NAEP test, students have to read complex nonfiction texts that require high background knowledge.
“Do you know what we ask kids to read on the NAEP test?” said Kim. “We ask them to read about the U.S. Constitution. We ask them to read about the human body system. We ask them to understand what metamorphosis is, and that is what we have to do next as we think about making progress in the science of reading …
“We’ve made progress in the science of reading simple text, yes. Now we need to make progress in the science of reading difficult science, math and English language arts text.”
Campus & Community
Rising econ star sheds light on power of exchange rates
Oleg Itskhoki, now a Clark Medalist, returns to Harvard
Christy DeSmith
Harvard Staff Writer
March 12, 2025
5 min read
Oleg Itskhoki.Veasey Conway/Harvard Staff Photographer
Exchange rates aren’t a hot topic in the U.S., due to the dollar dominating global trade and acting as the benchmark for all other currenc
Rising econ star sheds light on power of exchange rates
Oleg Itskhoki, now a Clark Medalist, returns to Harvard
Christy DeSmith
Harvard Staff Writer
5 min read
Oleg Itskhoki.
Veasey Conway/Harvard Staff Photographer
Exchange rates aren’t a hot topic in the U.S., due to the dollar dominating global trade and acting as the benchmark for all other currency valuations.
“But in most countries of the world, the exchange rate looms very large,” said Professor of Economics Oleg Itskhoki, Ph.D. ’09. “In smaller open economies like Canada, Australia, Switzerland, or even Great Britain and Japan, the exchange rate matters quite a lot. Talk with central bankers in these countries, and they’re often more interested in the exchange rate than in inflation.”
Itskhoki, a rising star in international economics, joined the Harvard faculty last summer. The Russian-born macroeconomist is best known for partnering with Dmitry Mukhin on a series of papers showing why exchange rates against the U.S. dollar don’t always move with macroeconomic fundamentals like consumption, productivity, and monetary policy. Instead, factors in a country’s financial markets are the dominant driver.
At the center of the analysis is a more accurate framework for understanding exchange rates between currencies worldwide. Itskhoki was recognized for his work with the American Economic Association’s 2022 John Bates Clark Medal, a prestigious award recognizing significant contributions by economists younger than 40.
“There are really two branches of international economics: international trade and international macroeconomics. It’s very unusual but Oleg has established himself as a leader in both. He’s just a tremendous intellectual force.”
Kenneth Rogoff
“But even if Oleg hadn’t won the Clark Medal, he would be someone we want in this department,” said Kenneth Rogoff, a professor of economics and Maurits C. Boas Chair of International Economics. “There are really two branches of international economics: international trade and international macroeconomics. It’s very unusual but Oleg has established himself as a leader in both. He’s just a tremendous intellectual force.”
Itskhoki, whose resume includes professorships at UCLA and Princeton, initially landed at Harvard as a Ph.D. student in the mid-’00s. His advisers included Elhanan Helpman, Ph.D. ’74; Pol Antràs; and Gita Gopinath (on leave since 2019 for leadership roles at the International Monetary Fund).
All three faculty veterans partnered with Itskhoki on research related to trade, globalization, and inequality. A series of papers with Gopinath and the late economics professor Emmanuel Farhi turned a macroeconomic lens on the real-world impacts of border taxes.
“When you announce an import tariff, your exchange rate appreciates immediately and this actually hurts your exporters even before the tariff is in place,” Itskhoki explained. “Few people outside the economics profession appreciate the fact that an import tariff is, in fact, equivalent to an export tax — a very import and rather general insight from a 1936 paper by Abba Lerner that has been quite central for a lot of my research.”
But Itskhoki situates his work squarely in the tradition of Rogoff, a leading expert on international finance who served as the IMF’s chief economist from 2001 to 2003.
In 2001, Rogoff co-authored an influential paper advancing a unified theory to explain many of the big puzzles in international macroeconomics. The purchasing-power-parity puzzle, for example, concerns how prices for the same product can vary from one country to the next even when adjusted for exchange rates.
Starting in 2016, Itskhoki partnered with Mukhin, now with the London School of Economics, to rethink many of the puzzles related to exchange rates in Rogoff’s analysis. Itskhoki and Mukhin’s first paper, published in 2021, introduced a simple model that solved these puzzles while more accurately predicting exchange rates between currencies worldwide.
As for the purchasing-power-parity puzzle, Rogoff chalked it up to citizens’ preference for domestically produced goods. Itskhoki’s work offered additional insights.
“He fleshes out the role of financial markets as well as the importance of monopoly in modern economies,” Rogoff explained.
This puzzle-solving research agenda is far from concluded. Itskhoki and Mukhin just published the second major paper in their series, expanding their framework to challenge previous exchange-rate modeling that hinges on factors such as inflation, productivity, or consumer demand.
“We show that forces like demand for a country’s assets must be more important in shaping the exchange rate than forces related to supply of goods and monetary policy.”
Oleg Itskhoki
“We show that forces like demand for a country’s assets must be more important in shaping the exchange rate than forces related to supply of goods and monetary policy,” Itskhoki said.
Two more publications are also in the works, both available now as working papers. The first lays out how economic sanctions impact exchange rates, with the test case being valuations of the ruble following Russia’s full-scale invasion of Ukraine in 2022. The other draws on the whole series to offer guidelines for policymakers worldwide.
“Should countries form a currency union like the Eurozone?” Itskhoki offered. “What are the costs and benefits of abandoning independent currencies — of adopting a common monetary policy — but losing the exchange rate flexibility? Is it good for the central bank to set a floating exchange rate? Should they partially fix it? Fully fix it? It was odd to discuss these questions without a reliable framework that could reproduce the actual properties of exchange rates.”
Tom Osborn (left), Eve Driver, and Ari Kohn. Veasey Conway/Harvard Staff Photographer
Campus & Community
How to escape your silo (spoiler: friendship helps)
Co-authors of ‘What We Can’t Burn’ formed lasting bond even as they argued about best way to fight climate change
Christy DeSmith
Harvard Staff Writer
March 12, 2025
5 min read
Eve Driver and Tom Osborn agreed that the world urgen
How to escape your silo (spoiler: friendship helps)
Co-authors of ‘What We Can’t Burn’ formed lasting bond even as they argued about best way to fight climate change
Christy DeSmith
Harvard Staff Writer
5 min read
Eve Driver and Tom Osborn agreed that the world urgently needed to ditch fossil fuels. But the Harvard College classmates, both engaged with campus conversations on climate change, saw very different ways of getting there.
Driver viewed the push for carbon-free energy sources as a historical analog to the Civil Rights Movement.
“But Tom was like, ‘No, this is much more akin to when we switched from horses and buggies to cars,’” Driver recalled.
Each slowly came to see the wisdom in the other’s perspective, with direct, and often difficult, conversations, proving the building blocks of a lasting bond. Driver and Osborn went on to publish “What We Can’t Burn: Friendship and Friction in the Fight for Our Energy Future” (2024). In a recent appearance at the Edmond and Lily Safra Center for Ethics, they read from the book and traded insights on fostering connections like the one they forged as Class of ’20 undergrads.
“When I discovered this book, I found it so moving that it entered my own research on friendship and politics,” offered Ethics Center Director Eric Beerbohm, the Alfred and Rebecca Lin Professor of Government and senior adviser of the FAS Civil Discourse initiative. “I told them, ‘You’ve almost created a genre here.’”
Osborn, who studied psychology, had been the teenage founder of a clean cooking fuel company in his home in Kenya. He was in high school when his mother was diagnosed with a respiratory tract infection, caused by inhaling smoke while cooking with charcoal, the local standard.
“I grew up in a setting where government doesn’t really work,” Osborn said. “I thought, if someone’s going to solve this clean cooking problem for my mom, it’s not going to be the government. It was going to take an entrepreneur to do it.”
Driver, who grew up in suburban Boston loving Ralph Waldo Emerson, remembered being skeptical of Osborn based, in part, on the name he chose for his company: GreenChar.
“The climate crisis demands radical and uncomfortable forms of cooperation between people with all kinds of reasons not to trust or talk to each other.”
Tom Osborn and Eve Driver
“I was very skeptical about greenwashing,” said Driver, now a Brooklyn-based writer and strategist focused on the clean energy transition. “There’s a lot of companies I was learning about that advertised themselves as green but were really not very green.”
“What We Can’t Burn” alternates between the voices of Driver and Osborn during their junior year at Harvard, a memoir-like format that captures how sparring partners can evolve into trusted pals who expand each other’s thinking. “The climate crisis demands radical and uncomfortable forms of cooperation between people with all kinds of reasons not to trust or talk to each other,” they write in the introduction.
The Feb. 27 conversation touched on an event, explored at length in the book, that nearly broke their relationship: Driver’s involvement in a fossil fuel divestment protest that halted a 2019 Kennedy School event featuring then-Harvard President Larry Bacow.
“I felt like that tactic was to some extent alienating,” said Osborn, now the co-founder and CEO of the Shamiri Institute, a public benefit organization delivering mental healthcare to young people across Africa. “I was just like, ‘If you’re going to be going around campus shutting down people, I don’t want to be friends with you.’”
Event moderator Ari Kohn ’26, a social studies concentrator and undergraduate fellow at the Ethics Center, asked about the particularities of maintaining their connection on campus. “My experience at Harvard has been that people have really self-segregated among people who have very similar beliefs as them,” said Kohn, who also co-chairs the Intellectual Vitality student advisory board.
Osborn attributed these divisions to the siloed nature of academia, with experts from different fields working separately: “The consequence of that is we don’t have a lot of modeling for what it takes to engage in these conversations outside of combative debates.”
“The consequence of that is we don’t have a lot of modeling for what it takes to engage in these conversations outside of combative debates.”
Tom Osborn
Debating Driver on the best way to decarbonize helped open his entrepreneurial mind to the role policymaking can play in bringing renewables to market, he said.
“I was guilty of the siloing that I was accusing people in academia of,” he confessed, citing the “heavily subsidized” SolarCity, acquired by Tesla in 2016, as just one example of a clean energy venture to get a boost from government partnerships.
“We both had a lot of authentic questions that we couldn’t really answer within our circles,” Driver said. “I was so inspired by so many of the academics and activists and writers I was reading. But at the same time, I knew there was a limit, just from a disciplinary perspective. None of them have ever built an energy company.”
Arts & Culture
Art as omen in turbulent times
Joseph Koerner with Max Beckmann’s “Self-Portrait in Tuxedo” (1927) at Harvard Art Museums.Stephanie Mitchell/Harvard Staff Photographer
Eileen O'Grady
Harvard Staff Writer
March 12, 2025
8 min read
In new book, Joseph Koerner dissects reaction to 3 works created during political unrest
When Joseph Koerner first began teaching Dutch pain
Joseph Koerner with Max Beckmann’s “Self-Portrait in Tuxedo” (1927) at Harvard Art Museums.
Stephanie Mitchell/Harvard Staff Photographer
Eileen O'Grady
Harvard Staff Writer
8 min read
In new book, Joseph Koerner dissects reaction to 3 works created during political unrest
When Joseph Koerner first began teaching Dutch painter Hieronymus Bosch at Harvard in the 1990s, he saw him as the “typical medieval artist” preoccupied with sin, chaos, and danger. But as Koerner uncovered more information about how Bosch’s works have been interpreted over the centuries by panicked people in times of political upheaval, the story began to shift.
“Now, one almost feels like one is looking to Bosch for what we are supposed to do under our own emergency situation,” he said. “Instead of being way back in the past, he seems to have become a cipher for the present and an omen for the future.”
Koerner’s latest book, “Art in a State of Siege,” seeks to capture “that feeling of looking at works of art as ‘omens’” by examining three images: Bosch’s “The Garden of Earthly Delights” (circa 1490-1500), Max Beckmann’s “Self-Portrait in Tuxedo” (1927), and an animated drawing by William Kentridge of a dead victim of state violence disappearing into the South African landscape (1993). Koerner writes about the political situations that inspired these works, and how they captivated historical figures from the Spanish King Philip II to Nazi jurist Carl Schmitt.
The book was partly inspired by a personal connection: Koerner’s father, the artist Henry Koerner, created works that addressed the trauma of the Holocaust. In this edited conversation with the Gazette, Koerner discusses shifting ideas of “the enemy” and other themes raised by the works.
Where does the phrase “art in a state of siege” come from?
It was coined by Kentridge in 1986 at a moment in South African history when the white apartheid government decided the unrest that they perceived themselves to be facing was of such magnitude that they had to suspend the rule of law indefinitely. In its first meaning, “siege” is a condition in which a city or fort is surrounded by enemy forces. But in modern-state formations, leaders in times of civil war can declare a state of siege where you treat your own people as if they’re enemies. Every modern constitution has some loophole in it, by which laws, rights, and privileges can be temporarily suspended. The sieges that figure in my book are of the latter type. What I’m exploring is less about the artists, and what they made and how they responded to siege, than about what art looks like in states of siege. The book tries to grasp a relationship between viewers and works of art in which the artwork vacillates between something that’s very dangerous, and something that might give some signal of what to do in terrible circumstances.
What makes Bosch’s tryptic “The Garden of Earthly Delights” so intriguing?
Famously, no one knows how the central panel relates to the outside panels. Is hell (in the right panel) a punishment for the central scene, or is the central scene a continuation of the Adam and Eve scene (left panel), one in which the Fall never happened and everything’s happy? No one has been able to definitively decide that, and on that hinges the whole painting. The question is: Is the image positive or negative? Are we looking at a friend or are we looking at an enemy?
“Amity finds no toehold in Bosch’s hostile carousel of love,” Koerner writes.
Hieronymus Bosch, “The Garden of Earthly Delights,” (c. 1490-1500)
What kinds of enemies does Bosch depict?
He almost programmatically makes you not quite sure who the enemy is. Bosch wanted to magnify different siege conditions: the feeling that the self is besieged by sin; the feeling that Christian Europe is besieged by Islam; the feeling there’s a conspiracy of people called witches and heretics who are secretly occupying your town. Ultimately the enemy in Bosch seems to be the old enemy, Satan, who lies behind all devilry. But Bosch gives enough specifics that a person could take more concrete enemies and direct violence against them. In many of his paintings there’s a small, often slightly hidden, flag of the Ottoman Empire in the distance, as if to say, “This is what Europe will look like once the siege is over and the enemy has breached the gates.” There are also racial slurs and anti-Jewish slurs, and there’s even a sense that the poor in the city might be enemies.
You write about how viewers project their own experiences onto “Garden.” Could you talk about that?
In times when things are at their worst, Bosch suddenly comes into favor. One of the things I was fascinated by is how a group of right-leaning and Nazi intellectuals became obsessed with Bosch — there’s evidence from their letters. They realize they’re losing the war. They believe the crimes that they perpetrated are going to come back to haunt them. They already feel themselves to be victims. Carl Schmitt, Ernst Jünger, and Mircea Eliade are having these conversations, and they look to Bosch to give them a sign of what’s going to happen to them. I found a memoir that Schmitt wrote while he was in prison in Nuremberg for possible war crimes, in which he’s imagining in his cell Bosch’s “Garden of Earthly Delights.” He sees the painting as the enemy because for him it’s liberalism, it’s free love, it’s a lawless world, a world in which every hell has broken loose. I found out that Schmitt was the first person to hear Wilhelm Fraenger’s crazy theory that “The Garden of Earthly Delights” is actually in favor of the pleasures that it represents, that it was painted for a secret group of free-love advocates called Adamites, ruled by a Jewish convert. So this idea existed that it was a Jewish work, and hedonistic. This scholarly error seemed very, very interesting to me.
What interested you about Max Beckmann and his self-portrait that’s at the Harvard Art Museums?
There’s almost no self-portrait in the history of art that is as boldly frontal as this huge self-portrait in the Busch-Reisinger Museum. Because it’s rather simple, the little details really start to get conversation going — like the cigarette in his hand, and the fact that he’s looking straight ahead. And the more you look at it, the more stuff comes out.
The painting was created at a moment when there was a break from the repeated failures as a parliamentary democracy in post-WWI Germany — a respite from the collapse into political chaos due to the fight between left-wing and right-wing paramilitarized groups. In 1927 Beckmann decides, in a moment of wild artistic optimism, to say, with the painting and an accompanying manifesto, that the artist is the one who creates balance and stops chaos by being the decider of the polity, and the decision that the artist makes is the work of art itself.
It’s not an unusual idea at the time that art is a power or force that can be weaponized. The Nazis, of course, famously weaponized art. It wasn’t by accident that Adolf Hitler was an aspiring artist, that Nazi leadership theorized Hitler and the Nazi movement as a “sculptor” using humans as their work of art. In 1937 the Nazi leadership mounted this very peculiar art exhibition to vilify, repudiate, and degrade works of art on display by calling that art “degenerate.” The idea was to put the enemy on display. In the aftermath of this “degenerate art” exhibition, Beckmann’s painting was put on auction and went via a Swiss dealer to Harvard Art Museums.
What is the value of studying art from times of political unrest?
Art has that characteristic of becoming relevant whether you like it or not. For the most part, people understand art in terms of victories: The artist is victorious over the problems that face them and becomes “the great artist.” And even the art historian, the person who shows how the artist won: In so doing, they win their own case in their book or article. My kind of art history is different than that. My art history is about art that comes up in times of trouble, in which there’s not victory but the potential for severe defeat. “Art in a State of Siege” is a way of showing, on a broader canvas, what art looks like, not under victory circumstances, but in troubled times.
Arts & Culture
Every picture tells a story
Photographer Susan Meiselas (left) speaks with attendees following the talk.Stephanie Mitchell/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
March 12, 2025
5 min read
Photographer Susan Meiselas shares how ‘44 Irving Street Cambridge, MA’ shaped her career
Susan Meiselas didn’t set out to be a photographer. The documentary ph
Photographer Susan Meiselas (left) speaks with attendees following the talk.
Stephanie Mitchell/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
5 min read
Photographer Susan Meiselas shares how ‘44 Irving Street Cambridge, MA’ shaped her career
Susan Meiselas didn’t set out to be a photographer. The documentary photographer, filmmaker, and president of the Magnum Foundation was working toward her master’s degree at the Harvard Graduate School of Education in 1971 when she shot her groundbreaking “44 Irving Street, Cambridge, MA series,” which is now on view at the Harvard Art Museums.
Best known for her documentary photography of the late 1970s insurrection in Nicaragua and her photos of carnival strippers later that decade, Meiselas looked back on the Irving Street black-and-white prints during a recent gallery talk and shared how they helped shape the career that followed.
Initially, she said, she was focused on her degree when a course in photography “with a sociological bent” caught her eye. (She no longer remembers the name of the course.) For a class project, she chose to shoot the other inhabitants of her Cambridge boarding house.
“The camera was this way to connect,” she said. “I knew no one, and I began to knock on doors.”
Going around to the different apartments, she realized that each space in the old building “had a different character.” Seeing how the residents personalized their rooms, “I became fascinated by what they did with their space.”
Visitors gather to examine the photographs Meiselas discussed.
Stephanie Mitchell/Harvard Staff Photographersity
Even more captivating than the personal use of space, Meiselas found, were the interactions with her neighbors, whom she identified only by their first names. To start with, she would explain that she was a student, learning photography. “I’d ask them if there was a place in their room that they would sit for a portrait.” The results vary, with subjects settled into easy chairs or lounging on the floor, some in clean, well-lit areas and others surrounded by books and papers. Once she developed the photos, she’d return with a contact sheet to show her subjects. “That was the moment where something else for me happened,” she said. After her subjects had viewed the photos, she would ask them, “How do you feel about yourself?”
Those written responses, which can be read by accessing a QR code on the exhibit wall, make the installation complete, said Meiselas, who submitted the letters along with the photographs for class. “They wrote me either about how they felt about themselves, how the picture did or didn’t portray them.”
At the gallery talk, she read excerpts of those responses aloud. Her former neighbor Gordon, for example, is shown slumped in a chair, with books and a television behind him. “I wouldn’t have chosen to live alone. I was forced to,” he wrote, perhaps to explain his dejected posture. “That’s the way I am, somewhat distant. I get turned in on myself. I look at this place as a way station.”
In other samples of the QR-accessible text, another neighbor, Carol, responded to her photo, which shows her surrounded by her books. “I like to think my face conveys the way I feel during my most creative jam sessions: slightly dissatisfied at my slowness, slightly chagrined by the progress and quality so far lacking.” Another, Barbara, focused on herself: “My picture shows me … in my small world,” she wrote of the photo, which shows her typing at a desk, “looking out at everyone and everything.”
Those letters became Meiselas’s focus. “I didn’t leave class thinking ‘I’m going to be a photographer,’” she said. Instead, “I became fascinated by the camera as a point of connection.”
What interested her, she continued, was how the subjects responded. The experience also raised two themes that have become constants in her work: “the pleasure of the connection, and the problematic nature of the power of representation.”
Meiselas explored these themes recently in the book “Collaboration: A Potential History of Photography,” which she calls “an attempt to really look at photography as including others.” (The book was co-authored with UC Berkeley Professor of African American Studies Leigh Raiford; Yale University Professor of Women’s, Gender, and Sexuality Studies Laura Wexler; photographer Wendy Ewald; and Brown University Professor of Modern Culture and Media Ariella Aïsha Azoulay.) Such an examination is necessary, she said, because the relationship between the subject and the photographer can be fraught, balanced between “what’s positive and collaborative and inclusive and participatory, and what is more problematic.”
After the “Irving Street” project, Meiselas went on to get her education degree and teach. Working with elementary school students at an experimental school in the South Bronx, she again incorporated photography into her work. Using simple pinhole cameras, her students took photos of their surroundings and their neighbors “and made little books,” she recalled.
“They used images to tell stories. It wasn’t about the formalism of photography,” she said. “It was about the narrative and the connectivity. It was: Take your pinhole camera, go out on the street, meet the butcher…” Through these photos, Meiselas said she hoped to give her students “a notion of photography as an exchange in the world.”
Through all these projects, she sees the thread of relationship-building. Looking back once more on the “Irving Street” series, she noted: “This project has always resonated as the beginning of my practice.”
Photographs from Susan Meiselas’ “44 Irving Street, Cambridge, MA” portfolio are on display at the Harvard Art Museums through April 6.
Nation & World
NIH funding delivers exponential economic returns
Credit: National Eye Institute, National Institutes of Health
Sy Boles
Harvard Staff Writer
March 11, 2025
3 min read
Report finds all 50 states reap gains in patient health, job creation, research resources, business development
A new report from the nonprofit United for Medical Research (UMR) shows that every dollar o
Credit: National Eye Institute, National Institutes of Health
Sy Boles
Harvard Staff Writer
3 min read
Report finds all 50 states reap gains in patient health, job creation, research resources, business development
A new report from the nonprofit United for Medical Research (UMR) shows that every dollar of research funded by the National Institutes of Health (NIH) delivers $2.56 in economic activity, a multiplier effect that extends the agency’s impact as the largest public funder of biomedical research in the world.
In fiscal year 2024, the report found, the agency awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide. The funding supports a broad range of institutions in states across the nation, including academic research centers, private companies, startups, and advocacy organizations.
The 2025 update noted NIH-funded research has improved patient health; boosted job creation directly and indirectly; supported the purchase of research-related goods and services; and produced spin-out companies that drive tax revenue and attract innovation-intensive businesses. The new report arrives amid growing concerns over future funding levels for the federal agency.
By fueling basic scientific research, the NIH helps the U.S. maintain its position as a leader in the global life sciences, medtech, and biopharmaceutical industries. Forty-six percent of all basic research in the nation is conducted at academic research institutions, and most of that work is funded by the federal government, according to UMR, a coalition of leading industry groups and research institutions, including Harvard University.
At Harvard, NIH funding supported the development of an AI tool called Clinical Histopathology Imaging Evaluation Foundation, or CHIEF, which made huge strides in diagnosing cancer and guiding treatment. Other NIH-funded projects include developing a procedure to repair once-untreatable eye damage; creating a new class of antibiotics to combat drug-resistant infections; finding new ways to fight depression; and deepening our understanding of neurodegenerative disease, among other projects.
The UMR findings come in the wake of a 2023 report showing the exponential economic impact of research funding in rural states. In the nation’s seven most rural states, NIH funding generates an average return of $2.30 for every dollar invested and supports an average of 2,300 jobs and $353 million in new economic activity per state.
That research also yielded important regional benefits. West Virginia has the nation’s highest overdose rate and suffered numerous outbreaks of HIV and hepatitis C in recent years, issues that have overlap owing to their links to hypodermic needles and other drug paraphernalia. West Virginia University researcher Judith Feinberg has used NIH funding to integrate care for substance use disorder and infectious diseases in local health centers.
“NIH research happens everywhere,” said UMR President Caitlin Leach. “Whether you are from a red state or blue state, there are very real economic benefits to your state because researchers there receive NIH grants. That NIH research funding saves lives and fuels local economies throughout the United States is a very powerful message.”
NIH funding, in fact, historically has been a bipartisan priority. The agency’s budget has grown by more than $17 billion since fiscal year 2015. UMR warned that a constrained NIH budget in fiscal year 2025 and beyond could decrease the agency’s effectiveness and potentially undermine the nation’s dominance in biomedical innovation and as a hub for training the next generation of scientists, physicians, entrepreneurs, and educators.
Arts & Culture
Wishing real world wasn’t starting to feel so much like her dystopian novel
Celeste Ng. Photos by Melissa Blackall
Clea Simon
Harvard Correspondent
March 11, 2025
5 min read
Celeste Ng discusses new book about mother and son, how the personal becomes political — and vice versa
The personal is political in Celeste Ng’s books. In her three best-selling novels, the Cambri
Wishing real world wasn’t starting to feel so much like her dystopian novel
Celeste Ng.
Photos by Melissa Blackall
Clea Simon
Harvard Correspondent
5 min read
Celeste Ng discusses new book about mother and son, how the personal becomes political — and vice versa
The personal is political in Celeste Ng’s books. In her three best-selling novels, the Cambridge resident highlights Asian American characters and how issues around ethnicity and cultural origin can create tensions for them, both in their families and in the wider world.
Her third and latest novel, “Our Missing Hearts,” follows a mother and biracial son in a future Cambridge where behavior considered unpatriotic is criminalized and can result in children being taken from their parents. Here “un-American” art and books are banned, and an underground network of librarians keeps such books — and our knowledge of the past — alive.
The novelist noted her dystopian creation is starting to feel increasingly familiar amid all of the global headlines.
“I was really hoping the world would move further away from the novel,” said Ng ’02 during a conversation with Erika Lee, the Carl and Lily Pforzheimer Foundation Faculty Director at the Schlesinger Library and Bae Family Professor of History. The event was part of the Kim and Judy Davis Dean’s Lecture Series at Harvard Radcliffe Institute.
The seed of the novel was personal experience, rather than politics, she explained. “When I got the idea for this, it was focused on this mother, Margaret, a Chinese American woman and her son, who is mixed race, and goes by the nickname Bird,” said Ng, who is also the mother of a son. (She made a point of noting during the event that while her work draws from her life it is fiction, not memoir.)
At the time, she said, “I was doing a lot of book tours. I was on the road a lot, and I was thinking ‘Does he resent me being away from home so much?’” This, she acknowledges, is a return to familiar themes. “In ‘Little Fires Everywhere,’” her 2017 bestseller that was turned into a 2020 Hulu miniseries, “There’s a mother who asks her daughter to sacrifice quite a bit. I started asking what if the child wasn’t really on board? What is it that a mother who is creative might have to sacrifice for her child? What if a child saw his mother’s creative work as a rival for his mother’s time?”
That question led to her vision of a future dystopia, “maybe 1 or 2 degrees off of our reality,” she said. The harrowing vision “didn’t take a lot of imagining, honestly,” said Ng. “I really wish we as a country learned more from our history.”
In the book, one group — Persons of Asian Origin — are “particularly suspect,” Lee said. This mirrors the anti-Asian bias that arose during the COVID-19 pandemic, when Ng was working on the book. But Ng said she’s “always been aware” of this bias.
Other people — specifically non-Asian people — weren’t, she found.
“When violence began against Asian Americans … a lot of people were really surprised,” said Ng. “The Asian people I know were not surprised. The violence against us was always imminent. But you don’t know what you don’t know. I wanted to highlight that, and as the COVID pandemic kept going, and we started to see a lot of the violence, it seemed important to bear witness.”
Being idealized — the flip side of being scapegoated — is not much better for Asian Americans, she said. “You’re the model minority. You’re used as this wedge to push other groups out of the center or even downward.”
These days, Ng said, people have been turned off by the news, and many have felt the need to withdraw. However, in this tumultuous time, art — including literature — can bridge the gap.
“Fiction can come in sideways. It can get around your immediate reaction to what might be the front page of the headlines.” Citing “resistance art” installations that dramatized the family separations of the first Trump administration, she said, “If you bypass the intellect and go straight for people’s emotions, sometimes you can spur people to action.”
Turning the discussion to the writing process, she acknowledged her first drafts are “very inefficient.” If every book begins with a question, she explained, “Writing the first draft is where I tend to figure out where my question even is.”
Along those lines, she rejectedthe idea of using AI in the writing process, particularly in the beginning of a project. Writing a first draft engages “the space where hopefully you were thinking about stuff,” she explained. “The more you use [AI], the less your brain gets exercised.”
Addressing the problems of tokenism — of being labelled “the next Amy Tan” — she talked about how many stories need to be told.
“There’s not a single story that encompasses not only all Asian Americans but all Chinese Americans, or Chinese American women,” she said. “We’re getting stories that are not especially about being Asian, but in which the character’s ethnicity and background experience are part of them and part of what shapes them, but maybe not the whole story.”
Ng concluded that in the end, people will see her work as inspiring.
“I want ‘Our Missing Hearts’ to be a story that gives people hope,” she said. “It is a novel, essentially, of me trying to find hope.”
Campus & Community
Telling apples from Apples
Students using card catalogs at Widener Library, 1945. Courtesy of Harvard University Archives
Tenzin Dickie
Harvard Library Communications
March 11, 2025
4 min read
Harvard Library search tool will understand intent behind the terms
In the 50 years since card catalogs moved online, the way we search for library materials has stayed much
Students using card catalogs at Widener Library, 1945.
Courtesy of Harvard University Archives
Tenzin Dickie
Harvard Library Communications
4 min read
Harvard Library search tool will understand intent behind the terms
In the 50 years since card catalogs moved online, the way we search for library materials has stayed much the same. Users enter keywords into a search, the system looks for those keywords and returns results.
As collections and data have grown exponentially, it’s become more complicated to finetune for the right results. If you search a library catalog for “the history of Apple,” you’ll get results mainly for the fruit rather than the company. The system only understands the words, not the meaning.
A Harvard Library team is building a new search tool to change that.
Using generative artificial intelligence and semantic search technologies, its new Collections Explorer will break through the limitations of keyword search to decipher the intent behind your words. It will allow you to ask questions and carry out your search in natural language.
What poems of Emily Dickinson’s include handwritten marginalia? What does Harvard have on the history of germ theory development? Tell me about the Black empowerment movement in America.
Imagine asking any of these questions, exactly as they are worded, on the library’s website and getting the results you’re really looking for. Soon, you can.
Pioneering a new model of search and discovery
With more than 20 million physical and digital items in dozens of formats — from ancient manuscripts to journal articles to one-of-a-kind maps and original poetry recordings — finding the right item for your research in Harvard’s vast collections is a complex endeavor.
For librarians and technologists at the library, the rise of generative AI presents an opportunity to tackle this problem while challenging conventional thinking about traditional library search.
Martha Whitehead, University librarian and vice president for Harvard Library, recognized that library searches needed to evolve, and she charged her team with finding a way to incorporate AI into search.
“How can Harvard Library model what is possible in this brave new world of library discovery enabled and enhanced by AI?” she asked.
Collections Explorer is slated to launch publicly in the fall.
Photo by Scott Murry
Partnering with Mozilla.ai, the nonprofit’s division dedicated to open-source and trustworthy AI, a Harvard Library team lead by Stu Snydman, associate University librarian and managing director of Library Technology Services (LTS), a Harvard Library and Harvard University Information Technology (HUIT) team, got to work.
“Keyword search is now 50 years old,” said Snydman. “With our new discovery system, we demonstrate how recent generative AI technologies, such as large language models (LLMs), can intersect with established AI technologies to create a powerful tool for finding and discovering information.”
The three-month partnership with Mozilla.ai originated from a HUIT Emerging Technology and Innovation Program pilot and led to a prototype for a new AI-driven search tool, Collections Explorer. Built by LTS, in collaboration with colleagues across the library and support from AI experts within HUIT, the tool uses generative AI to search across repositories and collection formats. Its alpha release, which just completed user testing, is slated to launch publicly in the fall.
Using Collections Explorer
The Collections Explorer is intuitive and transparent. Suppose you’re curious about Chinese artwork at Harvard. You can type in your question — “Does Harvard hold any artwork from China?” — as if you’re talking to a librarian.
Along with results from the Harvard Art Museums’ archives and collections of Chinese calligraphy and painting, you’ll also see illustrations of Chinese plants from a global botanical illustration collection. The results include explanations of why they’re a match for your prompt.
The Explorer also suggests additional prompts, such as “Notable Chinese paintings and sculpture at Harvard University” or “Exploring the Chinese art treasures housed at Harvard.” Serendipity and creativity are built into the system.
Ask the tool “What does Harvard have on the history of germ theory development?” and along with results from the library’s collections, the system suggests you try: “How did public education campaigns of the 19th century intersect with germ theory?” or “What are techniques for antiseptic surgery?” Each new prompt opens a new possibility for inquiry.
“With Collections Explorer, our new discovery system for the AI age, Harvard Library meets the needs of its community and the public in new and innovative ways,” Whitehead said. “We look forward to the next 50 years.”
Arts & Culture
Letting the portraits speak for themselves
Artist Robert Shetterly ’69 and Brenda Tindal, chief campus curator. Photos by Niles Singer/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
March 11, 2025
5 min read
New exhibit elevates overlooked voices as it explores hope, change, and how we see others
In 2002, two Harvard affiliates, artist Robert Shetterly
Artist Robert Shetterly ’69 and Brenda Tindal, chief campus curator.
Photos by Niles Singer/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
5 min read
New exhibit elevates overlooked voices as it explores hope, change, and how we see others
In 2002, two Harvard affiliates, artist Robert Shetterly ’69 and the late Harvard Medical School Professor of Neurology S. Allen Counter, launched portraiture projects driven by a desire for change. Shetterly, disillusioned by the U.S. government’s decision to go to war in Iraq, had turned to painting people who inspired him as a form of protest and solace. Meanwhile, Counter, the founding director of the Harvard Foundation for Intercultural and Race Relations, wanted to address issues of representation by diversifying the portraits displayed across Harvard’s campus.
“Every one of the people I paint has a particular kind of courage that meets a particular moment,” Shetterly told chief campus curator Brenda Tindal in front of an audience at Cabot House. “They take the risk, often, of being either ostracized by society or legally entangled, something that’s going to put them in some oppositional relationship with large segments of this country. I am so drawn to that. It’s because of that courage that we have social justice.”
“Every one of the people I paint has a particular kind of courage that meets a particular moment”
Robert Shetterly
Portraits of Regina Jackson (left) and Pauli Murray by Robert Shetterly. The use of quotes was partly inspired after Shetterly learned that most gallery attendees only spend seven seconds in front of a painting. He wanted to encourage viewers to slow down and look.
Last week, the Office for the Arts, the Harvard Foundation, and the Harvard College Women’s Center staged an exhibition at Cabot that highlighted portraits of Harvard affiliates from both projects. Titled “Seeing Each Other: A Conversation Between the Harvard Foundation Portraiture Project and Americans Who Tell the Truth,” it included paintings from Shetterly and the Portraiture Project’s Stephen Coit ’71.
In honor of Women’s Week, the portraits spotlighted female changemakers, including former U.S. Treasurer Rosa Rios ’87, musicologist Eileen Southern, civil rights activist Pauli Murray, ethnomusicologist Rulan Pian, youth development advocate Regina Jackson, and former Maine State Sen. Chloe Maxmin ’15. Portraits of Counter and W.E.B. Du Bois, the first Black Ph.D. to graduate from Harvard, are also included.
“History reminds us that the fight for gender equity has often been strengthened by allies who have used their platforms to challenge injustice and uplift the voices of those most marginalized,” said Habiba Braimah, senior director of the foundation, introducing the conversation between Tindal and Shetterly. “By showcasing their portraits alongside the extraordinary women we honor tonight, we acknowledge that meaningful progress is achieved through both advocacy and solidarity, reinforcing the idea that the pursuit of gender equity has always been and must remain a shared responsibility.”
Robert Shetterly’s newly unveiled portrait of Sherrilyn Ifill.
At the exhibition opening, Shetterly also unveiled a new portrait of civil rights lawyer Sherrilyn Ifill, former president of the NAACP Legal Defense Fund, who was Steven and Maureen Klinsky Visiting Professor of Practice for Leadership and Progress at Harvard Law School from 2023 to 2024. In the portrait, Ifill, wearing a blue suit jacket, gazes outward with a thoughtful expression, chin resting on one hand.
Having attended Iffil’s 2024 Dr. Martin Luther King Jr. Commemorative Lecture at Harvard, Adaolisa Agbakwu ’28 remembered being moved by the lawyer’s analogy of the Civil Rights Movement as a cycle of planting and harvest — laying groundwork so future generations can reap the benefits.
“The portrait’s warm and the cool undertones spoke to me of this almost solace within her but also this fiery passion and energy that she has toward her work and dedication to the cause that she exhibits in everything she does,” Agbakwu said.
In his discussion with Tindal, Shetterly said that what began as a plan to create 50 portraits for his series has since grown into a collection of more than 200. Shetterly took his first art course at Harvard — a drawing class in the Carpenter Center for the Visual Arts.
“What I noticed was that when I had to look at something — my own hand, an apple, a pencil, an old shoe, a glove — in order to draw it, I had to really see it for the first time,” Shetterly recalled. “That changed my life.”
Shetterly paints on wood panels with brushes, palette knives, and his fingers, and uses a dental pick to carve a quote from his subject into the wood above their likeness. The use of quotes was partly inspired, he said, by hearing that most gallery attendees only spend seven seconds in front of a painting and wanting to encourage viewers to slow down and look.
“Having the words incised into the surface gives them a slightly different weight than if they have been painted on the surface,” Shetterly said. Once in the painting, they seem to be a little bit stronger, more organic, as though they really come from the person in the painting.
Coit, who has contributed more than two dozen portraits to the Harvard Foundation Portraiture Project, told the audience that he feels his role is to showcase what his subjects want to reveal about themselves.
“When I was painting somebody I would say, ‘What do you want to say in your portrait?’” Coit said. “We’d think about the background, we’d think about what they were wearing, we’d think about the expression on the face, and they would create it with me. I always felt my job was a little bit to create a kind of immortality, so it felt like they were in the room with you, delivering that message.”
Campus & Community
House pride from
Illustration by Judy Blomquist/Harvard Staff
March 11, 2025
1 min read
Housing Day is more than a tradition, as first-years soon learn
On March 13, Cambridge residents may catch a glimpse of glittery green-eared bunnies racing through Harvard Square, or a pack of polar bears lumbering from Radcliffe Quad as screams of “Domus!” echo across Harvard Yard.
Not to w
Housing Day is more than a tradition, as first-years soon learn
On March 13, Cambridge residents may catch a glimpse of glittery green-eared bunnies racing through Harvard Square, or a pack of polar bears lumbering from Radcliffe Quad as screams of “Domus!” echo across Harvard Yard.
Not to worry. It’s just another Housing Day at Harvard.
For the uninformed, on Housing Day first-year students are awakened in the early hours with news of where they will be living for the next three years. The sorting is randomized, and the residences are as distinctive as the individuals who inhabit them.
Here are some of the unique sources of pride of the 12 traditional Houses plus the Dudley Co-op, from A to Z.
Illustration by Liz Zonarich / Harvard Staff
Science & Tech
Life-changing brain tech, but with a chilling caveat
Sy Boles
Harvard Staff Writer
March 10, 2025
5 min read
Fellow’s paper finds a warning in dark chapter in U.S. history
On Jan. 28, 2024, Noland Arbaugh became the first person to receive a brain chip implant from Neuralink, the neurotechnology company owned by Elon Musk.
Life-changing brain tech, but with a chilling caveat
Sy Boles
Harvard Staff Writer
5 min read
Fellow’s paper finds a warning in dark chapter in U.S. history
On Jan. 28, 2024, Noland Arbaugh became the first person to receive a brain chip implant from Neuralink, the neurotechnology company owned by Elon Musk. The implant seemed to work: Arbaugh, who is paralyzed, learned to control a computer mouse with his mind and even to play online chess.
The device is part of a class of therapeutics, brain-computer interfaces (BCIs), that show promise for helping people with disabilities control prosthetic limbs, operate a computer, or translate their thoughts directly into speech. Current use of the technology is limited, but with millions of global cases of spinal cord injuries, strokes, and other conditions, some estimates put the market for BCIs at around $400 billion in the U.S. alone.
A new discussion paper from the Carr Center for Human Rights welcomes the potential benefits but offers a note of caution drawn from the past, detailing unsettling parallels between an era of new therapies and one of America’s darkest chapters: experiments into psychological manipulation and mind control.
“In the past, there have been actors who were interested in controlling people’s minds,” Lukas Meier, the paper’s author and now a fellow at the Edmond & Lily Safra Center for Ethics, said in an interview. “It’s not implausible that in the future there will be such actors, at whichever level, state or private sector, who might attempt the same but with improved technology.”
“It’s not implausible that in the future there will be such actors, at whichever level, state or private sector, who might attempt the same but with improved technology.”
Lukas Meier
Meier, a former technology and human rights fellow at the Carr Center, was referencing the Cold War, when scientists on both sides of the Iron Curtain participated in a dangerous race for control of the human mind. In 1953, in response to allegations that the North Korean, Chinese, and Soviet governments had successfully brainwashed American prisoners of war, then-CIA Director Allen Dulles authorized MKUltra, the CIA’s controversial attempt at eliciting confessions and controlling people’s behavior.
“That was indeed their aim; they just didn’t get very far, as far as we know,” Meier said.
According to Meier’s report, in one project, subjects were made to listen to recordings on a loop, including during drug-induced sleep, in an attempt to alter their personalities. In another experiment, subjects were given strong electric shocks multiple times a day for weeks at a time, sometimes while they were on psychoactive drugs. Some subjects lost key memories or even the ability to speak a second language; some lost the ability to walk or eat without support. Many suffered lifelong physical or mental consequences.
The CIA’s methods were crude, Meier said, but if the more advanced methods of the 21st century steer clear of the worst effects of MK Ultra, they have the same implications for self-determination, consent, and mental privacy. For instance, parents in China sounded the alarm in 2019 over schoolchildren wearing devices that tracked their brainwaves to improve their focus. In more theoretical applications, researchers have explored reconstructing images from the brain signals of people wearing BCIs.
“With these technological capabilities, we move dangerously close to inadvertently enabling one of the main goals of Cold War intelligence programs: the eliciting of information from subjects who are not willfully cooperating,” Meier writes.
“With these technological capabilities, we move dangerously close to inadvertently enabling one of the main goals of Cold War intelligence programs: the eliciting of information from subjects who are not willfully cooperating.”
Lukas Meier
Meier speculates that in addition to decoding our thoughts, BCIs could be used to change our behavior. He describes research showing that some patients receiving deep brain stimulation for Parkinson’s disease experience manic symptoms, including a 2006 case in which a patient with no previous criminal record broke into a parked car when the stimulator was activated, then returned to normal when the stimulation stopped.
“Making somebody without any criminal record break into a car seems to be a pretty strong interference,” he said, adding: “We’re not at a point where you could create this effect at will. It can happen as a byproduct, but I don’t think anyone could predict which type of neuromodulation applied to which area of the brain could produce this effect, at least not with any accuracy.”
Despite Meier’s misgivings, he supports the continued development of BCI technology in the U.S., in part to stay ahead of global adversaries.
“It is during times like these, in particular, that technological innovations which are becoming available to the opposing parties are at high risk of being misused in order to gain an advantage,” he writes in the paper. “The dire consequences of the manifold attempts at developing techniques for mind control during the Cold War should act as a warning. The two dangerous ingredients are recurring: a resurgence of bloc confrontation and the availability of innovations employable for interfering with the human brain. We may not be able to rely on technological limitations thwarting efforts at mind control a second time.”
Health
Did a socially awkward scientist set back airborne disease control?
Carl Zimmer.Photos by Niles Singer/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
March 7, 2025
5 min read
In talk on new book, Carl Zimmer theorizes key researcher’s discoveries were undercut by his personality
In the “Great Man” theory of history, outsized personalities make things happen. But when
Did a socially awkward scientist set back airborne disease control?
Carl Zimmer.
Photos by Niles Singer/Harvard Staff Photographer
Clea Simon
Harvard Correspondent
5 min read
In talk on new book, Carl Zimmer theorizes key researcher’s discoveries were undercut by his personality
In the “Great Man” theory of history, outsized personalities make things happen. But when it comes to public acceptance of the science behind airborne diseases, Carl Zimmer hypothesized, a boring and unpleasant personality may have slowed progress.
Zimmer, the 2016 recipient of the Stephen Jay Gould Prize for his contributions to the public understanding of evolutionary science, did not set out to tell the story of one such person as he tracked our “long, slow, very difficult realization that the air around us is alive.” But in a recent talk about his new book, “Air-Borne: The Hidden History of the Life We Breathe,” he kept returning to former Harvard researcher William Firth Wells.
“Air has always been captivating and mysterious to us,” said Zimmer as he walked the audience at the Science Center through the main thread of his book: the discovery — and ultimate acceptance — of the concept that pathogens can be transmitted through the air.
In ancient Greece, Hippocrates first proposed the theory of “miasmas,” bad air that by itself carried sickness, rather than microorganisms carried by air, said Zimmer. Even more than a century after the discovery of microbes, in the 1830s when cholera struck Europe, the idea that the disease was transmitted through the air was not taken seriously. That began to change with the research of scientists such as Gottfried Ehrenberg, who in the 1830s began the first systematic study of microorganisms, and Louis Pasteur, whom Zimmer credits with “championing the germ theory of disease.”
But air continued to be overlooked in responses to disease outbreaks. “Again and again these diseases were linked to microorganisms that were spread in food, in water, through sex … but not in the air.”
“Again and again these diseases were linked to microorganisms that were spread in food, in water, through sex … but not in the air.”
Enter the work of Wells, who with his wife, Mildred Weeks Wells, a medical doctor, began to experiment with a centrifuge. Wells’ earlier work, cleaning water to raise disease-free oysters, had led him to experiment with the device, and in 1934, while lecturing at the Harvard School of Public Health, he used one to sample the air of the hall three times. The first time was after he dispersed a sneezing powder in the air, the second once that powder had taken effect, and the third after the students had left. Cultivating the samples he gathered in the centrifuge, he found what he considered powerful evidence that human exhalations spread microbes through the air.
Unfortunately, Zimmer said, “It was a terrible lecture.” Quoting a note by the dean of the School at the time, David Linn Edsall, he read, “This is the type of work Wells does extremely badly.” Further describing Wells as the type of person who could “talk for hours,” Zimmer went on to chronicle how the professor’s off-putting personality repeatedly cost him positions, setting back what should have been groundbreaking research.
At Harvard, Wells developed his theory of airborne infection and discovered that airborne pathogens could be killed by ultraviolet light. However, conflicts with his boss, Gordon McKay Professor of Sanitary Engineering Gordon Maskew Fair, over credit for these discoveries got him fired.
It was a pattern that would repeat for the rest of Wells’ life. At the University of Pennsylvania, where he next worked, he created “infection chambers” — airtight chambers that allowed researchers to control the ventilation reaching the animals inside — and again showed how airborne pathogens cause disease and how UV could destroy these pathogens. This research helped protect a school in 1940, when a measles outbreak hit Philadelphia. But when World War II broke out, and military researchers were desperate to keep soldiers healthy, the unpleasant Wells was once again excluded.
Only the arrival of his former assistant, Richard Riley, helped salvage his career. Together, they created a version of the infection chamber in a Baltimore Veterans Administration hospital. Isolating patients with tuberculosis, they controlled their ventilation — siphoning their air, and thus their contagions, into a separate chamber where guinea pigs were held. Sure enough, the animals contracted the disease, confirming the validity of Wells’ hypothesis. Unfortunately, before the research could become universally accepted, Wells fell ill from cancer and also started exhibiting psychotic episodes. In a cruel irony, he was treated and died in that same Baltimore VA hospital.
Taking questions about the future of such research — and about how dependent it is on the personalities of researchers and of so-called great men, Zimmer was not optimistic. “We’re a long ways off from the Wellses, but this kind of work takes years. It’s hard work. … And the pathogens don’t care.”
Zimmer is the adjunct professor of molecular biophysics and biochemistry at Yale and writes the “Origins” science column for The New York Times. The event was part of the FAS Division of Science’s Harvard Science Book Talks.
Officials inspect a donation of food aid during a January 2024 ceremony in Harare, Zimbabwe. Tsvangirayi Mukwazhi/AP file photo
Nation & World
How planned major U.S. foreign aid cuts expected to shake out abroad — and at home
Former diplomats see unnecessary deaths, lost opportunities for American corporations, workers, and diminished geopolitical influence
Clea Simon
Harvard Correspondent
March 7, 2025
How planned major U.S. foreign aid cuts expected to shake out abroad — and at home
Former diplomats see unnecessary deaths, lost opportunities for American corporations, workers, and diminished geopolitical influence
Clea Simon
Harvard Correspondent
6 min read
Many more people around the world will unnecessarily die of AIDS and starvation; American farmers will take an economic hit; Russia and China will strengthen ties with less-developed nations formerly friendly with the U.S., forging new political loyalties — and potentially reaping future economic gains.
This is some of the possible fallout from the Trump administration’s recent decision to make deep cuts in programs for foreign aid, such as USAID and the U.S. President’s Emergency Plan for AIDS Relief, known as PEPFAR, according to a panel of former diplomats.
“We are going to have to think about different ways of doing things,” said Reuben E. Brigety II, former U.S. Ambassador to South Africa in the Biden administration on Feb. 27 during the first of a planned series of online discussions organized by the Harvard Center for International Development (CID) with government leaders, policymakers, and NGO experts that will examine the future of American foreign aid.
“There is no scenario in which American international or domestic interests are better served absent the robust presence of American leadership abroad. None.”
Reuben E. Brigety II, former U.S. Ambassador to South Africa
Brigety noted that the pullback will loosen ties between the U.S. and large parts of the global community, with multiple consequences, both expected and unexpected.
“None of this changes the fact that pandemic diseases know no borders,” he said. “None of this changes the fact that there are going to be emergencies” that will require international coordination.
A forecast by Richard A. Boucher, former U.S. ambassador to Cyprus, was more pointed. “People are going to die,” he said, listing AIDS and starvation as threats, as well as death “at the hands of murderous regimes over whom we don’t have influence” because of our withdrawal of aid and diplomacy.
Boucher, who was also former deputy secretary general of the Organisation for Economic Co-operation and Development and U.S. assistant secretary of state for South and Central Asia, said that other nations, less aligned with our interests, may rush in behind us.
“If we don’t have that seat at the table, China is going to step in,” he said. “We’re going to lose influence globally; we’re going to lose influence individually; and the United States is going to be poorer for it.”
Brigety agreed. “There is no scenario in which American international or domestic interests are better served absent the robust presence of American leadership abroad. None.”
That kind of stepping up, he said, “helps access to foreign markets for American goods.” In addition, partnerships with foreign governments grant us “access [to information on] very specific threats to American interests, including American lives.”
Former U.S. Ambassador to Greece and Ukraine Geoffrey Pyatt offered an example: In sub-Saharan Africa, he said, “USAID’s Power Africa program spent about a billion since 2013 facilitating and de-risking power generation.”
This was done with U.S. corporate partners, including Chevron and ExxonMobil, “American companies who were leveraging Power Africa activity to expand their markets,” said Pyatt, who is also former assistant secretary of state for energy resources. The results thus far? The program has “leveraged $29 billion” for the United States’ corporate partners.”
Boucher pointed out that American farmers benefit from the billions of dollars’ worth of grain that USAID buys to distribute abroad, as do American workers who travel to help build and manage new infrastructure created through foreign aid.
“America has always wielded influence because we had the money and the power. Take away the money, it means we’re walking on one leg,” he said.
As we withdraw, Brigety continued, all the Chinese have to say is: “‘See, you can’t trust the Americans.’”
Discussion moderator Fatema Z. Sumar, executive director of the CID, shifted the conversation to other future forecasts.
PEPFAR, Brigety explained, not only strengthened African healthcare as it distributed drugs and services to combat AIDS, but also strengthened that of the continent with lasting results. “Some of the earliest and best research on the planet about how to address COVID in the midst of the pandemic happened in South Africa.”
In the field of energy, the panelists outlined logistical and other challenges.
The U.S. has spearheaded the deployment of $5 billion in energy assistance to Ukraine, the majority of which came from the 29 other countries and multilateral organizations involved, Pyatt said. “But it is only USAID that has the grant-making authority, the power to push that money out the door,” he said.
“It worries me greatly that we have dismantled this capacity — because the next time, imagine there’s a Chinese attack on Taiwan — we’re not going to have the toolkit to accomplish this.”
We are losing “the institutional memory of those who were able to do this work,” he said.
Boucher added, “You don’t have the influence if you don’t show up.” Historically “we were the ones who able to go in and talk to people and make things happen.”
Instead, Brigety reiterated, that means China, Russia, and private organizations will step in, with Pyatt listing U.S. government institutions such as the Development Finance Corporation. Among those are former private USAID contractors, he said.
“If I were a USAID contractor whose 80 percent of funding just got yanked, I would immediately set up office in Jeddah [Saudi Arabia], in Dubai [UAE], and in Doha [Qatar], and probably Kuwait,” he said. “Many of those Middle Eastern countries see the economic opportunities on the continent and are interested not only in benefiting from it, but also realize that in order to benefit you actually have to help develop those economies.”
Sumar asked the panelists what they would say to students who have been preparing for careers in public service.
“The career has certainly become more challenging,” said Pyatt. Still, for those who may still be able to land jobs in the shrinking sector, “it’s a fabulous career,” he said.
“I can’t imagine anything in the private sector that delivers the level of psychic rewards that come from representing a country that is perceived to be the good guy in a contested international environment.”
Health
You went to the doctor and came out feeling worse
“If we use the term ‘gaslighting’ when intent is absent, we’re missing the opportunity for compassion for providers,” says psychologist Alexandra Fuss.Photo by Dylan Goodman
Alvin Powell
Harvard Staff Writer
March 7, 2025
5 min read
Psychologist who studied ‘medical gaslighting’ explains how caseload pressures contribute to the problem and w
“If we use the term ‘gaslighting’ when intent is absent, we’re missing the opportunity for compassion for providers,” says psychologist Alexandra Fuss.
Photo by Dylan Goodman
Alvin Powell
Harvard Staff Writer
5 min read
Psychologist who studied ‘medical gaslighting’ explains how caseload pressures contribute to the problem and when we should call it something else
Patients struggling with hard-to-detect conditions, such as long COVID, or with symptoms whose causes modern medical testing has trouble pinning down, such as irritable bowel syndrome, can feel dismissed when a doctor says they can’t find a cause for the ailment, or — worse — when they suggest that the condition may be all in the patient’s head. This is commonly known as “medical gaslighting,” a problem that is hardly new but which social media has amplified in recent years.
Alexandra Fuss, director of behavioral medicine in inflammatory bowel disease at Mass General and an instructor in psychology at Harvard Medical School, teamed with colleagues from the University of Michigan and the North Carolina-based Rome Foundation Research Institute to explore the issue for an article published in the journal Translational Gastroenterology and Hepatology.
In this edited interview, Fuss highlights the authors’ conclusion that most cases of medical gaslighting do not include an intent to deceive and should be called something else: “medical invalidation.” She also speaks to how growing caseload and paperwork pressures on doctors might be contributing to the problem.
How did the issue of “medical gaslighting” get your attention?
The term has blown up on social media, and, as a psychologist, I hear about it in sessions with patients.
Is there some medical hubris involved, when a provider can’t find a concrete reason for symptoms, so believes there isn’t one?
That’s part of it, and connects back to some thinking, “If it’s not something I’m seeing on a medical test, it’s probably psychological.” But we have to recognize that there’s also huge pressure on all healthcare professionals, especially M.D.s, to be experts, have answers, and to know everything. It can be difficult to say, “I don’t know.” But there’s so much room for growth if you say, “I’m not sure, but I’m going to work with you and we’ll figure it out together.”
You question whether “gaslighting” is the right term. Why?
There’s a lot of debate in the literature about the role of intent in gaslighting. Some authors say there has to be intent — to make somebody question their lived reality and defer to the perpetrator’s point of view — in order to have gaslighting. Others say it’s not about intent, it’s about the end results, and that whenever there’s a power differential, there’s potential for gaslighting.
We believe intent is key for true gaslighting. Whether consciously or subconsciously, I want you to see things my way and I’m going to question your experiences and throw you off of equilibrium so that you do.
If we use the term “gaslighting” when intent is absent, we’re missing the opportunity for compassion for providers. The vast majority have no intent to harm anybody. They are doing their absolute best to be healers and helpers. But sometimes there is “medically invalidating” behavior. It’s not intentional, but it’s still invalidating and it’s still harmful. And saying, “OK, this was invalidating,” rather than “gaslighting,” opens the door to asking, “How can we repair these relationships? How can we prevent this from happening?”
Can you talk more about how pressure on doctors might contribute to the problem?
These pressures start with hospital and organizational-level leaders who set the policies that ultimately impact the physicians working within these systems. Physicians are consistently pressured on productivity, to see as many patients as possible and often in as little time as possible. Also, studies show physicians are devoting upwards of 50 percent of their day to documentation, typically spending time outside of work to get everything done. They have to be stewards of healthcare resources and make sure patients aren’t getting unnecessary, expensive tests, and that resources are being used on the right people. There’s pressure all around them. It’s not surprising then that burnout rates are so high, affecting over half of physicians in practice. While it’s certainly helpful for providers to have skills in work/life balance, it’s unfair to say that this is completely on them and ignore the impact of the system they work within. Changes starting at the top can make a much bigger impact.
How does that pressure affect interactions with patients?
It leads to vulnerabilities for invalidation to happen. If, let’s say, a doctor has a heavy caseload that day and only 15 minutes for a visit with a patient and the patient takes the majority of the time talking, that doesn’t leave a lot of time for the provider to ask, “How are you doing with this?” Or to make those empathic statements that build trust: “I believe you, tell me more about what’s going on.” Without the time and space for the doctor to explain things, the patient is left filling in the blanks, which might look like, “Oh, my doctor is washing their hands of me” or “They waved me off.” If some of that pressure wasn’t there, these situations could be avoided.
Yoni Appelbaum. Photo by Jessica Torch
Nation & World
Americans used to move around a lot, chasing opportunity. No more.
Yoni Appelbaum argues legal, political hurdles over past 50 years have had troubling economic, social consequences
March 7, 2025
long read
Excerpted from “Stuck: How the Privileged and the Propertied Broke the Engine of American Opportunity” by Yoni Appelbaum, lecturer in history a
Americans used to move around a lot, chasing opportunity. No more.
Yoni Appelbaum argues legal, political hurdles over past 50 years have had troubling economic, social consequences
long read
Excerpted from “Stuck: How the Privileged and the Propertied Broke the Engine of American Opportunity” by Yoni Appelbaum, lecturer in history and literature, ’14.
America is a nation of migrants. No society has ever been remotely so mobile as America at its peak. In the late 19th century, the heyday of American mobility, roughly a third of all Americans changed addresses each year. European visitors were astonished, and more than slightly appalled. The American, Michel Chevalier observed in 1835, “is devoured with a passion for locomotion, he cannot stay in one place.” On Moving Day, when leases expired in tandem, the greater part of a city’s population might relocate to new quarters between sunup and sundown, in a great jumble of furniture and carts and carpetbags. On average, Americans moved far more often, over longer distances, and to greater advantage than did people in the lands from which they had come. They understood this as the key to their national character, the thing that made their country distinctive. “We are a migratory people, and we flourish best when we make an occasional change of base,” explained one 19th century newspaper. “We have cut loose from the old style of human vegetation, the former method, of sticking like an oyster to one spot through numberless succeeding generations,” wrote another.
Every American has ancestors who decided to stop being oysters. The earliest of them came across Beringia and quickly peopled the land. Millennia later, people arrived from Europe and were just as quick to spread out, dispossessing those who had come before. But they did not simply arrive in one place and put down roots. Having come to this land, they never stopped moving. They loaded the cart, the wagon, the steamer trunk, or the moving van. They left the towns where they grew up to plant settlements, and then their children left those towns in turn to begin anew. In different eras, they headed in different directions: meadowlands and marshes, to graze their cattle; market towns, to ply their crafts; factories, to earn a wage; prairies, to lay claim to the land and till the soil; booming cities, to open a shop of their own. They went in search of economic opportunity, or liberty, or community. They went because they were forced to go, or because they sought freedom and equality. They went because they could not stay where they were, or because they did not want to. But they went.
The ceaseless migrations of the population shaped a new set of expectations. “When the mobility of population was always so great,” the historian Carl Becker observed, “the strange face, the odd speech, the curious custom of dress, and the unaccustomed religious faith ceased to be a matter of comment or concern.” A mobile population opened the possibilities of pluralism as diverse peoples learned to live alongside each other. The term “stranger,” Becker wrote, in other lands synonymous with “enemy,” instead became “a common form of friendly salutation.” In a nation where people are forever arriving and departing, a newcomer can seem less a threat to the settled order than a welcome addition to a growing community: “Howdy, stranger.” Mobility has long been the shaper of American character and the guarantor of its democracy.
Americans turned migration from the last resort of the desperate and the destitute into the exercise of a fundamental right. The Puritans arrived on American shores in the 17th century, they justified the abandonment of their proper homes and stations with the audacious claim that relocation can sometimes be respectable, or even laudable. They soon codified this right, the right to leave, into law. Their towns, though, were semi-sovereign entities, policing their boundaries, selecting their members, and regulating the behavior of their populations. Anyone could leave, but not just anyone could stay. Two centuries later, as the young United States pushed west, it would add a complementary liberty, if only to some the right to belong. Together, these ideas constituted a new and transformative freedom. Instead of allowing communities to choose their own members, Americans decided to allow most individuals to choose their communities.
A mobile population opened the possibilities of pluralism as diverse peoples learned to live alongside each other.
As Americans moved around, they also moved up. The extraordinary geographic mobility of the United States drove its equally distinctive levels of social and economic mobility. Though the process of moving was always wrenching, the pain of relocation real, people who went to new places often found new beginnings, new connections, new communities, and new opportunities. They had the chance to break away from stultifying social hierarchies, depleted farmland, and dead-end jobs. On average, migrants have always grown more prosperous than those who stayed in place, and conferred better futures on their children — a correlation that, remarkably, has remained robust across four centuries, in a society that has changed in countless other ways.
There were no guarantees. However green the grass appeared, many Americans crossed to the other side of the fence, only to find it withering beneath their feet. Boomtowns turned to ghost towns; entire industries became obsolete. And mobility was never uncontested. Waves of immigrants faced discrimination from those who had come only slightly before, turned away from communities they sought to join just because they were Irish, or Italian, or Jewish. Laws excluded the Chinese, and vigilantes hounded them from their homes. Women seldom enjoyed the full privilege of mobility, constrained by social strictures, legal barriers, and physical dangers.
And even after the end of slavery, Black Americans had to fight at every turn to exercise their mobility in the face of segregation and racist violence.
But members of all these groups, and others besides, kept moving whenever they were able, because they understood the link between mobility and opportunity. Where racists and nativists sought to keep new arrivals out, they insistently demanded to be let in. And when the first move didn’t work out, Americans of different backgrounds could always see some more promising destination beckoning them onward. They could light out for the territory, hit the road, stake their claim, or make a brand-new start of it in a city that never sleeps. Our culture is thick with the clichés of mobility.
The freedom to move opened space for political and religious diversity. People unhappy with the decisions their communities made were not locked into endless feuds, but could, with a minimum of capital, move to a place they found more congenial, voting with their feet. Social identities, too, were transformed from heritable characteristics into self-fashioned choices. The voluntary communities Americans created led to a remarkable flourishing of religious and associational life as new arrivals invested effort in building up relationships, making America a nation of joiners. Freed from the heavy weight of tradition, of the constraints of habit and precedent, the new nation became famed for its entrepreneurship and innovation and for the rapidity of its economic growth. Mobility distinguished the United States from the relative stasis of Europe. American institutions were tuned for the perpetual motion of the population, adapted to individuals relocating again and again in search of greater opportunity. The most distinctive features of the young republic all traced back to this single, foundational fact: Americans were always starting over, always looking ahead to their next beginning, always seeking to move up by moving on. Mobility has been the great engine of American prosperity, the essential mechanism of social equality, and the ballast of our diverse democracy.
But for the last 50 years, the engine of American opportunity has been grinding to a halt, throwing society into crisis. Americans have grown less likely to move from one state to another, or to move within a state, or to switch residences within a city. In the late 19th century, the heyday of American mobility, a third of all Americans might have changed addresses each year. In the 1940s and 1950s, about a fifth of Americans moved annually. By 2021, only one-twelfth of Americans moved. The drastic decline in geographic mobility is the single most important social change of the past half century, and perhaps the least remarked.
In 1970, about eight out of every 10 children turning 20 could expect to earn more than their parents did; by the turn of the century, that was true of only half, and the proportion is likely still falling.
What killed American mobility? There is no shortage of suspects. People have always been most mobile while they’re relatively young, and the country is aging. The median American was just 16 years old in 1800 and 28 in 1970, but more than 38 today. The spread of occupational licensing might have made it more costly to find jobs in new places. Or perhaps the answers reflect positive trends. As more women have gained entry into the workforce, two-career households might have found it increasingly difficult to relocate. The prevalence of joint custody makes it harder for members of divorced couples to move. More Americans own their homes, and renters have always been more mobile. Maybe Americans are just growing more successful and better able to locate jobs and communities that meet their needs, reducing their impulse to move someplace else. Maybe they are relying on remote work to stay where they are.
But none of these answers can possibly explain the broad, persistent declines in geographic mobility by itself, or even if you add them all together. The country may be older, but the drop has been particularly steep among younger Americans. The spread of occupational licensing is real, but most jobs aren’t licensed, and it accounts for perhaps 5 percent of the total decline. Two-earner households may be less mobile, but their mobility has declined in tandem with that of other groups. Mobility is down not just among homeowners but also among renters, and its decline antedates the rise of remote work. And just look around. Do Americans look happier and more satisfied to you?
But there is one more set of suspects, and the evidence for their guilt is damning: American mobility has been slowly strangled by generations of reformers, seeking to reassert control over their neighborhoods and their neighbors. At the beginning of the 20th century, reformers sought to apply the fruits of science and reason to manage growth, reimposing order and control on a jumbled and chaotic landscape that mixed shops and apartments in among the houses, and occupants of varied ethnicities and income brackets. Their chosen tools were building codes and restrictive covenants and zoning ordinances, designed to segregate land by use and class and race. New Deal bureaucrats next took up the cause, requiring local jurisdictions to apply these tools to their communities and putting new construction firmly under the purview of government. Then, in the postwar decades, skepticism of big business and big government led a new generation of activists to empower individuals and groups to challenge decisions made by bureaucrats. This varied lot of reformers acted from a wide mix of motives, some laudable and others despicable. Some would probably appreciate what they have wrought, while others would be appalled at the unintended consequences of their work. But taken together, the reforms that they enacted have created a peculiarly dysfunctional system. Almost all new construction in the United States now requires government approval, and anyone with sufficient time and resources and education can effectively veto that approval, or at least impose great expense and delay. The result is that in the very places that need it most desperately, housing has become prohibitively difficult to build. If the freedom to move was originally secured by allowing Americans to choose their own communities, then it has been undone by a series of legal and political changes that restored the sovereignty of local communities and allowed them again to select their own members.
These changes took hold so gradually that most Americans are unaware of how radically they have altered their society. For most of our history, a highly mobile population moved toward opportunity. When a place prospered, it quickly swelled with new arrivals. Builders rushed to meet the demand with housing. Farms gave way to clusters of houses, which turned into town houses, which sprouted into apartment buildings or even high-rises. But in today’s burgeoning metropolises and boomtowns, restrictions have effectively frozen the built environment. As a result, housing has grown artificially scarce and prohibitively expensive. A fortunate few can still afford to move where they want. Most people, though, would have to pay so much more for housing in prospering cities that offered better jobs that relocation would leave them worse off overall. Americans aren’t moving anymore, because for so many moving threatens to cost more than it delivers.
The costs of our national sclerosis are frightening to contemplate. More Americans have stopped starting new businesses. Between 1985 and 2014, both the total share of entrepreneurs in the population and the share of people newly becoming entrepreneurs fell by half. More Americans have stopped finding new jobs. Switching jobs frequently when you’re young correlates with occupational and economic mobility, but the share of people switching industries, occupations, and employers has fallen dramatically, particularly among younger workers; they’ve grown less likely to work for four or more employers by the time they’re thirty and more likely to work for just one or two. And more Americans are ending up worse off than their parents. In 1970, about eight out of every 10 children turning 20 could expect to earn more than their parents did; by the turn of the century, that was true of only half, and the proportion is likely still falling.
As grim as the economic indicators might be, the measures of social health are even more alarming. Compared with Americans at the beginning of the 1970s, the average American today belongs to about half as many groups. Church membership is down by about a third, as is the share who socialize with folks around them several times a week. A majority of Americans tell pollsters that their social isolation has left them anxious and depressed. Americans are having fewer children. And while half of Americans used to think most people could be trusted, today only a third think the same. So Americans aren’t starting new businesses, switching to better jobs, or climbing the social ladder the way they used to. They’re not joining groups, gathering in prayer, having kids, or hanging out the way they used to. They don’t even trust each other anymore. They are, in a word, stuck.
Health
A dietary swap that could lengthen your life?
Study finds replacing butter with plant-based oils cuts premature death risk by 17 percent
Ryan Jaslow
Mass General Brigham Communications
March 6, 2025
4 min read
Substituting butter with plant-based oils daily may lower risk of premature death by up to 17 percent, according to a new study out of Mass General Brigham, Harvard T.H. Cha
Study finds replacing butter with plant-based oils cuts premature death risk by 17 percent
Ryan Jaslow
Mass General Brigham Communications
4 min read
Substituting butter with plant-based oils daily may lower risk of premature death by up to 17 percent, according to a new study out of Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute.
The researchers examined diet and health data from 200,000 people followed for more than 30 years and found that higher consumption of plant-based oils — especially soybean, canola, and olive oil — was associated with lower total, cancer, and cardiovascular disease mortality, whereas butter use was linked with increased risk of total and cancer mortality. The results are published in JAMA Internal Medicine.
“What’s surprising is the magnitude of the association that we found — we saw a 17 percent lower risk of death when we modeled swapping butter with plant-based oils in daily diet. That is a pretty huge effect on health,” said study lead author Yu Zhang, research assistant at the Channing Division of Network Medicine at Brigham and Women’s Hospital and a student in the Department of Epidemiology at Harvard Chan School.
Butter is rich in saturated fatty acids, while plant-based oils have more unsaturated fatty acids. There have been many studies on dietary fatty acids, but fewer studies have focused on their primary food sources, including butter and oils.
“Even cutting back butter a little and incorporating more plant-based oils into your daily diet can have meaningful long-term health benefits.”
Daniel Wang, Brigham and Women’s
The new study analyzed dietary data from 221,054 participants in the Nurses’ Health Study, Nurses’ Health Study II, and Health Professionals Follow-Up Study. Every four years, the study participants answered questions about how often they had certain types of food. The researchers used the data to estimate participants’ consumption of butter and plant oils, including butter and margarine blends, spreadable butter added to food and bread, and butter used in baking and frying. Intake of plant-based oils was estimated based on the reported use in frying, sautéing, baking, and salad dressing.
The researchers also identified participants who had died and their causes of death. Using statistics to compare death rates across different diet intake levels, the researchers found that participants who ate the most butter had a 15 percent higher risk of dying than those who ate the least. In contrast, those who ate the most plant-based oils had a 16 percent lower risk of death than those who ate the least.
“People might want to consider that a simple dietary swap — replacing butter with soybean or olive oil — can lead to significant long-term health benefits,” said corresponding author Daniel Wang of the Channing Division. Wang is also an assistant professor in the Department of Nutrition at the Chan School and an associate member at the Broad Institute. “From a public health perspective, this is a substantial number of deaths from cancer or from other chronic diseases that could be prevented.”
The researchers also did a substitution analysis, which mimics how swapping butter for plant oils would impact health in a feeding trial. They found that substituting 10 grams of butter a day (less than a tablespoon) with equivalent calories of plant-based oils could lower cancer deaths and overall mortality by 17 percent.
“Even cutting back butter a little and incorporating more plant-based oils into your daily diet can have meaningful long-term health benefits,” Wang said.
One limitation of the study is that the participants are mainly health professionals, so they might not represent the U.S. population as a whole, the researchers said. In the future, they’d like to study the biological mechanisms underlying why this dietary change has such a large impact.
In addition to Zhang and Wang, Mass General Brigham authors include Katia S. Chadaideh, Yuhan Li, Yuxi Liu, Eric B. Rimm, Frank B. Hu, Walter C. Willett, and Meir J. Stampfer. Additional authors include Yanping Li, Xiao Gu, and Marta Guasch-Ferré.
This study was supported by research grants from the National Institutes of Health.
Photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
5 things we learned this week
Sy Boles
Harvard Staff Writer
March 6, 2025
1 min read
How closely have you been following the Gazette? Take our quiz to find out.
The woke left has a conflict of interest; a blinding eye injury may be treatable; interest in republics is surging; TikTok underestimated power of music; the
Donald Fanger in 2008.Harvard file photo
Campus & Community
Donald Lee Fanger, 94
Memorial Minute — Faculty of Arts and Sciences
March 6, 2025
6 min read
At a meeting of the Faculty of Arts and Sciences on March 4, 2025, the following tribute to the life and service of the late Donald Lee Fanger was spread upon the permanent records of the Faculty.
Donald Fanger liked to say that he was privilege
At a meeting of the Faculty of Arts and Sciences on March 4, 2025, the following tribute to the life and service of the late Donald Lee Fanger was spread upon the permanent records of the Faculty.
Donald Fanger liked to say that he was privileged to have worked in the golden age of American academic life. His many friends, colleagues, students, and readers bear witness to his outstanding contributions, formal and informal, to it as scholar, teacher, mentor, and citizen. Fanger’s education at the University of California, Los Angeles, the University of California, Berkeley, and Harvard and his faculty positions at Brown, Stanford, and Harvard certainly placed him in centers of academic prominence. His career advanced swiftly and decisively. He became a full professor while still in his 30s and devoted nearly 70 years to building vibrant communities in his fields and universities.
As a young professor at Brown (1962–1965), Fanger founded an important series of publications that brought the best of Russian literary criticism back into print. At Stanford (1966–1968) he directed the new Slavic languages and literatures division and set it on a true course before leaving for Harvard. Once here he helped steer his two departments, Slavic Languages and Literatures and Comparative Literature, toward new projects and orientations, including engagement with recent theories of literature. As one of few comparatists with fluency in Russian and a profound understanding of Russian culture, he helped to broaden the range of inquiry in both of his fields. His talent for sharing his love of literature made it possible for him to work with colleagues in other disciplines and, through his many reviews in public-facing journals, to extend his insights to non-academic audiences. While building his departments, he reached out internationally to bring students and scholars to Harvard. One search found him traveling to Poland to recruit the prominent young poet Stanisław Barańczak and then tenaciously battling to bring him to Harvard. Many wonderful dinner parties in the Fanger home helped welcome newcomers and visiting writers to the Harvard community. He remained a treasured interlocutor and active scholar in the 26 years that followed his retirement in 1998.
As a teacher, Fanger excelled in the seminar room and in the lecture hall. His mellifluous baritone and elegant, precise English made his courses unforgettable in both venues, as did his rigorous preparation, insightful readings, and ability to engage his students, regardless of their level of expertise. He worked with historians to offer large courses on Russian civilization for the undergraduate Core Curriculum Program and taught memorable lecture courses on a range of topics, including Dostoevsky, urban fiction, and theory of comedy. His advanced seminars on Russian realism and on 20th-century prose thoroughly prepared their participants for careers in scholarship and teaching.
Fanger’s own scholarship (three books and over 40 articles, primarily on Russian literature), like his teaching, grew from his lifelong fascination with the intricacy and often unresolvable complexity of literary texts. Written in remarkably subtle, controlled, but often dazzling prose, these studies seemed to be working simultaneously on a variety of levels. With his fluency in multiple languages, keen eye for textual detail, and attention to patterns within and across works, he made literary works come alive in new and unexpected ways. He had a particular fondness for experimental fiction, which he transposed into demonstrations of how familiar, canonical texts arose from their authors’ daring innovations in theme and structure. Believing that criticism rises toward the level of the material it addresses, he worked exclusively with challenging texts, framing his inquiries broadly in historical, social, and cultural contexts. His first book, “Dostoevsky and Romantic Realism: A Study of Dostoevsky in Relation to Balzac, Dickens, and Gogol” (1965), took the urban mythmaking of three writers who worked independently and showed how Dostoevsky, who knew their writing, developed its themes and techniques (the grotesque, the sensational, the unnatural) to craft a poetics of the city, which Dostoevsky called “fantastic realism.” Fanger’s second book, “The Creation of Nikolai Gogol” (1979), remains our most insightful and profound book on Russia’s first great prose writer. Fanger took the salient property of Gogol’s life and texts, elusiveness, and made it the key to interpreting not just Gogol’s texts but also his life and literary milieu. A pioneering contribution to literary criticism, literary sociology, and literary biography, the book won Phi Beta Kappa’s Christian Gauss Award in 1980. A year later, Fanger was elected to the American Academy of Arts and Sciences.
Fanger’s third book, “Gorky’s Tolstoy and Other Reminiscences” (2008), took him to a new period, the early 20th century; a new author, Maxim Gorky; and a new literary problem, how we remember figures who contribute to the literary process with much more than their imaginative writing. Gorky, one of the most popular Russian writers of the early 20th century, is now remembered primarily for his efforts in defense of Russian culture during the turmoil of the post-Revolutionary years and for the part he played in normalizing Stalinist literary politics in the early 1930s. But Fanger turned to Gorky’s works that have best stood the test of time, his insightful memoirs of Tolstoy, Chekhov, and others, selecting the most incisive of them and, with illuminating annotations, making them a reflection on writerly selection, arrangement, and interpretation. The volume became a casebook on Gorky’s legacy not as a myth or figure but as a talented creative artist.
Fanger’s many articles present readings of individual texts or contribute to the understanding of specific theoretical problems. A significant number of them address the principal agents in the making of literature: authors, readers, censors, and critics. Taken together they constitute a lifelong meditation on the literary process and on literature as an institution.
Fanger was married for 46 years to Margot Taylor Fanger, who passed away in 2001. In 2006 he married Leonie Gordon, who survives him. He leaves his three children with Margot, Steffen Fanger, Ross Fanger (Allyson Fanger), and Kate Fanger (Jeremy Jackson); six grandchildren; a stepson, Nicholas Gordon (Alison Haskovec); and three step-grandchildren.
On Nov. 8, 2024, a memorial gathering brought together many friends and family members to celebrate Fanger’s wit, erudition, endearing personal charm, and exceptional capacity for love and friendship.
Respectfully submitted, Julie A. Buckler Michael S. Flier Stephen Greenblatt Justin Weir William Mills Todd III, Chair
Ukrainian soldiers install explosives near the front line in the Donetsk region.Evgeniy Maloletka/AP
Nation & World
Finding insights in history for war in Ukraine
Christina Pazzanese
Harvard Staff Writer
March 5, 2025
4 min read
Scholars say that Russia may appear to be gaining upper hand currently, but challenges lie ahead
When Russia invaded Ukraine three years ago, President Vladi
Scholars say that Russia may appear to be gaining upper hand currently, but challenges lie ahead
When Russia invaded Ukraine three years ago, President Vladimir Putin frequently invoked history, falsely claiming his goal was to “denazify” Ukraine and harkening to the Soviet victory over Nazi Germany in World War II to rally the nation behind him.
History and its misuse have been central components of the war in Ukraine since its inception, Ukraine and Russia scholars observed during an online discussion Monday. But, they argued, looking at the actual record of the past can offer valuable insights into the current conflict and where it might be headed.
Serhii Plokhii, Mykhailo S. Hrushevs’kyi Professor of Ukrainian History, noted the war began on Feb. 24, 2022, not long after the Kremlin published an essay in which Putin falsely claimed Ukraine had occupied Russian territory and that Ukrainians had no culture or history independent of Russia.
Though Putin appears to be gaining the upper hand at the moment, the conflict could ultimately backfire on Russia in the long run.
War often has a “profound” effect on a country’s sense of national identity and on its state- and nation-building process, said Christopher Miller, ’09, a professor of international relations at the Fletcher School at Tufts University.
The most significant and lasting impact of the Russia-Ukraine war will be felt in Ukraine and what it has done to “further catalyze” and consolidate a nation-building process that Ukraine began before 2022.
“Ukrainians are more convinced than ever of the need to have two fully separate polities.”
Christopher Miller, Tufts University
“That speaks to the dilemmas that I think Russia finds itself in,” said Miller. “Having started a war on the thesis that Russia and Ukraine were, if not the same country, at least part of the same history, as Putin set it out in his [essay] in the summer of 2021, ending up in a situation in which Ukrainians are more convinced than ever of the need to have two fully separate polities.”
Miller said a war-weakened economy is unlikely to bring Russia to heel soon. The Russian government was well prepared for the conflict, making sure it had little debt and lots of savings and military stockpiles to draw from. Ordinary Russians haven’t experienced a decline in their standard of living — and some even feel better-off than before the war, because the Russian government has maintained aggressive social spending, and strong hiring by defense factories has boosted wages.
Through “creative accounting” Russia has been able to “hide a lot of the cost of the war” by borrowing heavily from Russian banks and government sources, which has insulated its economy from the war’s full impact — for now. But Russia’s financial troubles still loom on the horizon as “the likelihood that those loans get repaid is low,” he added.
A controversial proposal between Ukraine and the U.S. to divide Ukraine’s mineral reserves embodies a growing trend in recent years among the major world economies that have gone from seeing trade as “a positive-sum dynamic” to seeing trade as having “very clear zero-sum dynamics” that have forced “a new politicization of the international economy in ways we have not seen for some time,” said Miller.
For some, the negotiations to end the Russia-Ukraine war, which President Trump seeks to broker, have drawn comparisons to the Yalta Conference, the historic “Great Powers” meeting of 1945 held in then-Soviet Crimea, noted Plokhii, who is also director of the Ukrainian Research Institute at Harvard University.
It was there that President Franklin D. Roosevelt, British Prime Minister Winston Churchill, and Soviet leader Josef Stalin unilaterally mapped out the post-World War II global order, partitioning Germany and handing the Soviets a “sphere of influence” in Eastern Europe.
Unlike the current peace talks, the West at Yalta focused on ensuring some security for Poland and other territories under Soviet control, Plokhii said.
“What we are seeing today is that the interests of Ukraine … have been sacrificed” by decisions being made by outside forces, he said. “The lessons of Yalta still stand today: No lasting peace without those who are involved and affected the most.”
Atul Gawande.
Campus & Community
Atul Gawande named featured speaker for Harvard Alumni Day
Acclaimed surgeon, writer, and public health leader will take the stage at Harvard’s global alumni celebration on June 6
Laura Speers
Harvard Correspondent
March 5, 2025
5 min read
Renowned surgeon, best-selling author, and public health leader Atul Gawande, M.D. ’95, M.P.H. ’99, will be the fe
Atul Gawande named featured speaker for Harvard Alumni Day
Acclaimed surgeon, writer, and public health leader will take the stage at Harvard’s global alumni celebration on June 6
Laura Speers
Harvard Correspondent
5 min read
Renowned surgeon, best-selling author, and public health leader Atul Gawande, M.D. ’95, M.P.H. ’99, will be the featured speaker for Harvard Alumni Day, the annual University-wide celebration of the global alumni community hosted by the Harvard Alumni Association on June 6.
Driven by a relentless curiosity about how health systems function — and where they fall short — Gawande has devoted his career to rethinking not just how medicine is practiced, but how it is delivered to improve health outcomes for all. As a general and endocrine surgeon at Brigham and Women’s Hospital, a professor at Harvard Medical School and Harvard T.H. Chan School of Public Health, Gawande has fostered the next generation of physicians and health professionals. As assistant administrator for global health at the U.S. Agency for International Development under the Biden administration, he spent the past three years leading efforts to expand access to care, control health threats, and reduce disparities in life expectancy globally.
In addition, Gawande is widely recognized for his writing, which has broadened public awareness and understanding of modern health challenges and solutions across a wide range of topics. A contributor to The New Yorker since 1998, he has authored four New York Times best-sellers, including “Being Mortal: Medicine and What Matters in the End.”
“Atul Gawande is one of the most influential thinkers, writers, and innovators in health and medicine today,” said President Alan M. Garber ’77, Ph.D. ’82. “From advancing surgical safety to expanding access to high-quality care worldwide, he brings a deeply humanist perspective to his work and is dedicated to ensuring that healthcare policies and systems prioritize the people that they serve. I can’t think of a more fitting voice to inspire our alumni as they continue their own efforts to make a difference in the world.”
“I’m excited to return to Harvard,” said Gawande. “This is a community like no other — in its history, discoveries, and impact. And I’m continually inspired by alumni of all ages driving change for the common good, both within their local communities and around the world.”
Gawande has long been a force in health systems innovation, mobilizing people to take on entrenched challenges. His research has led to breakthroughs in patient care, including the widely adopted WHO (World Health Organization) Surgical Safety Checklist, a 19-item protocol credited with reducing surgical mortality rates by nearly half. Recognizing a critical gap from this work, he co-founded the nonprofit Lifebox in 2011 to make surgery safer by providing pulse oximeters to operating rooms worldwide. In 2012, he founded Ariadne Labs, a joint center at BWH and Harvard Chan School, to develop scalable solutions to some of health care’s most complex problems. He is currently an Ariadne Labs distinguished professor in residence.
He was a member of President Joseph Biden’s Transition COVID-19 Advisory Board and co-founded CIC Health, a public benefit corporation that supported pandemic response operations nationally. From 2018 to 2020, Gawande was the CEO of Haven, a joint venture launched by Amazon, Berkshire Hathaway, and JPMorgan Chase to revolutionize healthcare delivery.
A recipient of numerous honors, including a MacArthur “Genius” Fellowship, Gawande is a member of the National Academy of Medicine and was named one of the 100 most influential thinkers by Foreign Policy and Time magazine.
“A surgeon with the heart of a storyteller, Atul Gawande has a rare gift,” said HAA President Moitri Chowdhury Savard ’93. “He shows us that medicine is not just a science, but a profoundly human endeavor — one that demands reflection, empathy, and continuous improvement. Through his writing, research, and leadership, he challenges us all to ask: ‘How can we do better?’ I know his words will resonate with the alumni community as we reflect on what it means to lead lives of connection and purpose. It’s truly a privilege to have him join us.”
A Harvard homecoming
“I came to Harvard as a medical student and found an extraordinary community that has pushed me to think better, work better, and try for more than I ever imagined,” said Gawande. “Nothing that I have done since — surgery, innovation, writing, public health — was expected or possible without this place.”
Raised in Athens, Ohio, by physician parents who emigrated from India, Gawande has said that going into medicine felt so inevitable that he did everything he could to avoid it. He studied biology and political science at Stanford, then politics, philosophy, and economics as a Rhodes Scholar at Oxford. Even at HMS, his approach was unconventional — deferring admission for three years, then stepping away to work on healthcare reform in the Clinton administration.
After earning his medical degree and completing his second year of surgical training, Gawande’s next steps took him not to the laboratory, as was expected, but across the quad to Harvard Chan School, where he later earned a master’s degree.
It was during his surgical residency at BWH that The New Yorker first invited Gawande to write for them. Rather than play it safe, he tackled one of medicine’s most uncomfortable realities: medical errors — including a serious one that he had made. His many articles since then, unflinching in their examination of issues from end-of-life matters to skyrocketing health care costs, have redefined the public discourse on health.
“We are thrilled to have Atul Gawande join us for Alumni Day,” said Sarah Karmon, executive director of the HAA. “While the world around him — around us — advances at a rapid pace, he reminds us that true progress isn’t about scientific or technological innovation alone. We must also rethink how we care for each other. Atul’s work, whether in the operating room or on the written page, exemplifies knowledge in service to the broader community and demonstrates the difference that one person can make in the lives of others.”
Harvard Alumni Day will take place on campus and virtually on June 6. All alumni are invited to attend. For more information, visit alumni.harvard.edu/alumni-day.
Chetan Nayak, Microsoft technical fellow and professor, University of California at Santa Barbara. Photo by John Brecher for Microsoft
Science & Tech
Why new qubit may give ultrafast quantum computing a boost
Microsoft discovery appears to be more stable, robust option
Alvin Powell
Harvard Staff Writer
March 5, 2025
long read
Microsoft announced last month it had created a “topologica
Why new qubit may give ultrafast quantum computing a boost
Microsoft discovery appears to be more stable, robust option
Alvin Powell
Harvard Staff Writer
long read
Microsoft announced last month it had created a “topological qubit,” which the company says can power a quantum computer more reliably than previously developed quantum qubits and which they believe will speed development of ultrafast quantum computers capable of tackling the toughest computing challenges, far beyond the capability of even supercomputers built through conventional means.
The decades-old field of quantum computing seeks to harness the unusual forces at play at the subatomic level. Key is the idea of “superposition,” that something can be in two states at once.
In classical computing, information is stored as bits, either a 1 or a 0. In quantum computing, superposition means that information can be stored in a qubit as a 1 or a 0 or a combination. This increases the computer’s power exponentially.
In December, for example, Google unveiled a quantum chip that completed a computation in just five minutes that would take a conventional supercomputer 10 septillion years.
Microsoft’s topological qubit is constructed of indium arsenide and aluminum, which becomes a superconductor at very low temperatures. It is the result of nearly two decades’ work by a Microsoft team led by Chetan Nayak, Microsoft technical fellow and professor at the University of California at Santa Barbara.
In this edited conversation, Nayak, who got his start in physics as a Harvard College undergraduate in the late 1980s and early 1990s, spoke with the Gazette about the advance and about his experience treading the sometimes-difficult path of discovery.
How is Microsoft’s new qubit — the topological qubit — different from ordinary ones?
A qubit is a quantum mechanical two-level system. It’s something that can be a 0 or a 1, like a regular bit, but because of quantum mechanics, it can also be a superposition between 0 and 1.
That happens when you get down to microscopic enough scales and, as features on microprocessors have been getting smaller and smaller, we have been getting to the limit where quantum mechanics is going to start to matter for classical computing. That’s a problem because you want 0s and 1s to be very well-defined and not fluctuate in an unwanted way. But it turns out that’s also an opportunity.
Richard Feynman — and others — recognized as far back as the 1980s that nature is ultimately quantum mechanical so, if you want to simulate nature, you need to simulate it with what we call a quantum computer.
So problems in quantum mechanics, such as simulating materials like high temperature superconductors, or in chemistry, such as simulating catalysts that could be used for nitrogen fixation to make fertilizers or break down microplastics, those kinds of material and chemistry problems mostly have to be solved by experimental, high throughput, trial and error. It’s expensive and time-consuming.
With a quantum computer, you could simulate those things because it operates and takes advantage of the same underlying physical principles that nature uses.
The danger, though, is that your qubits will be like Schrödinger’s cat. It can’t, in the real world, simultaneously be a superposition of being dead and alive because the environment effectively gets entangled with it and collapses the wave function.
So, the qubits will eventually — or in some cases pretty quickly — lose the superposition. Then you lose all of the extra juice that you get from quantum mechanics. That’s part of what quantum error correction is supposed to solve.
“Actually holding that physical processor in my hand, and feeling the reality of it, that was pretty cool.”
A topological qubit is based on the idea that, given that you need to do error correction and you are worried about the fragility of quantum states, the more you can have that occur at the hardware level, the better the situation you’re in.
The idea is that the quantum mechanical states — the quantum mechanical wave functions — have similar mathematical structures, and if you can engineer, or find in nature, a physical system which organizes itself into quantum mechanical states in which those wave functions have that topological structure, then the information you coded will be very stable — not infinitely stable, but extremely stable and potentially without other very painful tradeoffs.
Maybe it doesn’t have to be huge; it doesn’t have to be slow; and it could be easy to control, because the amount of control signals that you have to put in is generally smaller. It’s hitting a sweet spot of embedding a lot of stability and rigidity to the wave functions without other painful tradeoffs.
So, it’s a more stable, a more robust system than the qubits being used now. How close is this to powering an actual computer?
Our ultimate goal is to have a million-qubit quantum computer. That’s a scale at which quantum computers are going to be able to solve these valuable problems, like new materials and chemistry.
It was in thinking about scale that we charted the roadmap we have. We didn’t want any solutions or any technologies that could only get to 100 or 1,000 qubits. Today, we only have a handful of qubits, as you saw on the chip that we’ve been showing off, but we have a roadmap to much larger systems.
We entered into a contract with DARPA, the Defense Advanced Research Projects Agency. Details aren’t public, but we have promised to deliver something pretty serious, that’s going to have fault tolerance, on a pretty aggressive timeline. It’s not going to be a million yet, but it’s going to be far enough along the road that it’s going to be very clear that we can get all the way there.
Life’s short. This is something I want to see in years, not decades, and our CEO does too.
It sounds like there were a number of major hurdles. What did you find most challenging?
In trying to make topological qubits, the situation for us in some ways was like going back to the early days of classical computing when people were building computers with vacuum tubes.
Semiconductors weren’t well understood, so there was a lot of fundamental research going on to understand what they are exactly. Sometimes they look like metals and sometimes they look like insulators. The fact that you can tune them in between is where their power is: the switchability and control.
People had to understand what properties were intrinsic and what properties were just due to some devices being dirtier than others. That led to the development of the transistor, but the first applications were years away — it was a while before it was computers — then came integrated circuits and you’re off and running.
We understood that you had to have the right material in order to get this new state of matter. We also understood at a reasonably early stage that the material had to have certain properties. It was going to have to be a hybrid between a superconductor and a semiconductor. It was going to need to put together many of the nice properties of a semiconductor and many of the cool properties of a superconductor. And we’d have to do this without introducing too many impurities or imperfections in the process.
Once we realized that was the first problem, the zeroth order thing that you can’t even get to “go” until you solve, and focused a lot of effort on that, then we were in a much better place.
“Our ultimate goal is to have a million-qubit quantum computer. … We didn’t want any solutions or any technologies that could only get to 100 or 1,000 qubits.”
Of course, in early days there’s going to be a lot of wandering around trying to figure it out. But I think the first step to solving a problem is clearly formulating what the problem is. If you don’t have a precise formulation of the problem, you’re probably not going to get to the solution. A very precise statement of the problem relied heavily on our ability to simulate these devices.
But we couldn’t use off-the-shelf simulations that people use in the semiconductor industry. The ideal thing would be if we had a quantum computer, which could simulate materials, but we didn’t have that.
So we had to develop custom, in-house simulations that enabled us to figure out the right materials combination and, of course, how to develop the synthesis and fabrication methods to make these new material types.
The third piece of that is testing. Once we had those three pieces, that wasn’t a guarantee of success, but that at least meant that we had a really good game plan and the ability to start turning the flywheel.
How did it feel to actually hold the chip in your hand?
It was pretty amazing, but when I first got chills down my spine was when I started seeing the data from one of these chips, where it looked like we expected it to. That was within the last year and one of those moments where there were absolutely chills down my spine and I said, “Oh, wow.”
In 19 years of work, there were setbacks, but especially in the last, let’s say, four years, there were a lot of moments where I said, “We actually kind of know what we’re doing here, and I see a path forward.”
There were a couple of times when we surprised ourselves with how fast we were able to go. But, without a doubt, actually holding that physical processor in my hand, and feeling the reality of it, that was pretty cool.
When you graduated from Harvard College in the early 1990s, your degree was in physics?
Yes, my undergrad degree was in physics at Harvard. I was there ’88 to ’92, and it was fantastic. I lived in Dunster House. I was back there last year to visit one of the labs. I got to run along the Charles River that morning and just walking from the hotel through Harvard Square over to the Jefferson Lab brought back a lot of good memories, though the Square has changed a lot.
I’m still in touch with my roommates and close friends from my time at Harvard. We have a WhatsApp thread that we all stay in touch on.
There’s not a lot of faculty there now who were there when I was a student, but there are a few emeritus professors and lots of great new faculty there, whom I didn’t know as a student but have known professionally as a physicist over the last 10 to 15 years.
You got started on this specific path with your doctoral work at Princeton?
I trace it back to some things at the end of my last year in Princeton, that’s when I first headed down this path. When I was an undergrad, I was interested in things vaguely like this, but quantum computing wasn’t really a field.
There’s been skepticism from some quarters expressed about your data. How do you answer the skeptics who say they don’t believe your results?
First, skepticism is healthy in science. It’s a normal part of the process, and anytime you do something really new, there should be skepticism.
We presented a lot of new results at the Station Q conference. It’s a conference that we have regularly, almost every year, in Santa Barbara that brings together over 100 people from across the field, from both universities and industry. There were one or two scientists from Harvard and also from Google and Intel.
The people who were at the conference heard about it for 90 minutes, got to ask questions, and were there for the rest of the conference to ask questions in informal discussions and over coffee, over dinner, and so on. But the rest of the community hasn’t heard it yet, hasn’t seen a paper yet, and there are a lot of questions.
So, there’s a group of people who’ve had a lot of exposure to the latest results, and that group is excited and has given very positive feedback, both on the work and the results. People who haven’t heard all the latest results are skeptical, and that’s natural.
I’m going to give a talk at the American Physical Society Global Summit — this is the 100th anniversary of quantum mechanics, the 100th anniversary of Schrodinger discovering his equation. I’m giving a talk there, and a lot more people will get to hear about our latest results.
We’re also putting out a paper in roughly the same time frame, so a lot more people are going to have a chance to see the very latest data and judge for themselves.
What happens next?
We put out a paper that lays out a roadmap. It’s not everything that we’ve shared with DARPA, but it’s the part that we think that we can make publicly available. We’re full speed ahead.
We are interested in these really big problems that ultimately come down to understanding nature better.
Some of my earliest work in physics involved trying to understand high-temperature superconductors. That was a big deal when they were first discovered because superconductivity was thought to be a phenomenon that only occurred at extremely low temperatures.
Then it was discovered that you can actually have things become superconducting above liquid nitrogen temperatures. It’s not fully understood why or how that happens, so our ability to make better versions of it or things that work at even higher temperatures is limited because we don’t even know where to look.
So I’m excited that some of these big scientific problems from the beginning of my career that I knew were important but didn’t know how to make progress on are things that we’ll be able to attack now with a quantum computer.
Science & Tech
When the woods are your climate change lab
Senior investigator Emery Boose and Director of Outreach & Education Clarisse Hart study changes in the Harvard Forest.Photos by Stephanie Mitchell/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
March 5, 2025
9 min read
For these researchers, Harvard Forest is a labor of love, and that love is changing
David
Senior investigator Emery Boose and Director of Outreach & Education Clarisse Hart study changes in the Harvard Forest.
Photos by Stephanie Mitchell/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
9 min read
For these researchers, Harvard Forest is a labor of love, and that love is changing
David Orwig tries not to think of changes in the natural world as “better” or “worse.” He just sticks with “different.” And after decades of warming winters, Harvard Forest today is decidedly different.
“Every day, walking around this forest is just dramatically different than it used to be,” said Orwig, who has worked at the 4,000-acre forest in Petersham, Massachusetts, since 1995 and today is senior ecologist. “When I first started working here, it used to be dark, green, lush, and shady. Now I take groups out there, and the overstory trees are letting in a lot more light. It’s gray in the understory, and there’s a whole new layer of birch coming in that was not here even 10 years ago.”
To Orwig and his Harvard Forest colleagues, climate change’s impacts aren’t an abstraction, and they aren’t a problem for tomorrow. That’s partly because climate change is studied there, but it’s also because many in the tight-knit community view their work as a labor of love. And it’s hard not to notice when your love is changing.
“We all have a landscape that we share here and care deeply about,” said Clarisse Hart, education and outreach director. “I guarantee that every single person who works here can tell you several parts of this land that are meaningful to them. We’re constantly out on the land together and experiencing these changes together.”
Black birch have begun to flourish in place of fallen hemlocks.
Hart points out the woolly adelgid on a hemlock branch.
The forest, founded in 1907, attracts researchers from around the globe because of its exceptional trove of collected data. It has temperature and precipitation information going back to the 1960s, with comparable data collected in the nearby town of Amherst going back to the 1830s. Having records collected over such a long period allows climate trends to emerge despite the normal variation in daily or annual weather figures.
“We now have enough data to say that the long-term trends toward a warmer and wetter climate, which is what the climate scientists have predicted for our part of the world, is being borne out,” said Emery Boose, senior scientist and information manager at the forest. “There may be some other trends as well. There’s evidence that there may be more variation from year to year. And precipitation, we’re starting to see evidence of extremely heavy, short duration rainfall, especially in the summer months, not tied to a large storm like a hurricane.”
Harvard Forest has about 100 research projects going at any one time, Boose said, ranging from small studies lasting just a single field season to ongoing efforts that are passed from one scientific generation to the next.
Experiments are installed along the dirt roads crisscrossing the forest, with some dug into the forest floor, artificially heating the soil to understand how ant and microbial communities might change in a warming world.
Others are hung off metal towers extending into and above the forest canopy, with cables and tubes running to nearby shacks where shelves of instruments examine gas exchange between the forest and the atmosphere.
“In the Southwest, the climate-and-tree story is one of drought and fire. It’s more in your face,” said Jonathan Thompson, senior ecologist and research director. “We have analogies for those things, but instead of drought and fire, it’s happening here through longer-term changes in climate interacting with invasive pests.”
The instruments also confirm things the researchers already know from personal experience: Winters are coming later despite this year’s more prolonged cold, and the snowpack is thinner. The fading winter cold gives way to summer heatwaves, more wildfires, and torrential rainstorms.
Signs of damage from the woolly adelgid, a small, invasive, aphidlike insect.
“My wife and I have been here for 40 years now, and we like to ski. Both anecdotally and in measurements, there’s a trend that snow doesn’t last quite as long and isn’t quite as deep as it used to be,” said Boose. “Plus, we’re both avid ice skaters and in 2023 for the first time I can remember one of the lakes in nearby Phillipston didn’t freeze over completely. I can’t ever remember that happening. We used to get one to two feet of ice.”
Other Harvard Forest administrators and scientists have similar stories: October 2023 passed without a frost until Halloween, and winter’s bitterest weeks are either milder (last winter logged no days below zero degrees Fahrenheit) or are reduced to a handful of days.
The stories vary by circumstance and experience, but they all point to the fact that the forest isn’t waiting for the debates to conclude in Washington, D.C. It is changing, with the most dramatic shifts affecting the very character of the forest.
“There’s nobody who hasn’t noticed that the hemlocks are dying,” Hart said. “I think what’s happening here is very real for all of us, and we could flop down and despair — seriously we could — but we’re also bolstered by a real sense of wonder at the resilience of ecosystems, at the way that trees work, the way these systems function.”
Hemlocks don’t just grow in a forest. They shape it, controlling the flow of energy via dense, multilayered branches that intercept much of the light that hits the canopy. Their fallen needles acidify the soil, keeping out competitors and forming a spongy carpet. They regulate temperature, shielding the snowpack from the spring’s strengthening sunshine and shading summertime streams to provide habitat for cold-water fish like trout.
When Orwig first came to Harvard Forest as a postdoctoral fellow, its hemlocks were healthy, but there were signs of change in the offing. So he traveled to southern Connecticut to glimpse the forest’s future.
He set up 40 monitoring plots to understand the woolly adelgid, a small, invasive, aphidlike insect that had arrived in Connecticut a decade earlier and was pushing north. The one thing that tends to keep them in check is cold temperatures.
Over the last two decades, however, the weeks of deep cold that used to be a feature of New England winters have moderated. So, the adelgid, a native of Japan, thrived in the milder landscape and started moving north to claim new territory.
Black birches give the forest a different feel, shady and green by summer, but sunny and open in the winter.
“We started with about 850 hemlocks,” Orwig said of his Connecticut plots. “There’s fewer than 50 left.”
Orwig continues to monitor those stands in hopes of finding “lingering hemlocks,” trees resistant to the adelgid that might serve as founders of a new, healthier population.
“I used to think I had two trees that were resistant in my plots, but when I went back several years later, they were both dead,” Orwig said. “There’s just not great evidence for resistance out there.”
Meanwhile, the woolly adelgid has spread relentlessly north, arriving in Massachusetts in 1988 and continuing into Southern New Hampshire, Maine, and Vermont.
Hope remains that resistant trees might still emerge, that an introduced insect predator might prove successful — several states have released them — or that a succession of cold winters, as occurred in 2004-2005, will knock down the population and give existing trees a chance to recover.
David Orwig (center) walks with Boose and Hart. Orwig marvels at the forest’s resilience, but says he will miss hemlocks as they continue to die.
Those hopes may seem slim, but Orwig points out that he never even thought Harvard Forest’s hemlocks would survive until now.
“I had envisioned that within 10 years, Massachusetts would all be dead and that hasn’t happened,” Orwig said. “That’s a good thing, but they’re still infested, and they still continue to decline.”
Dying hemlocks are usually replaced by deciduous trees, black birches in Harvard Forest’s case. Those trees give the forest a different feel, shady and green by summer, but sunny and open in the winter. The differences include soil chemistry — slightly basic as opposed to acidic under the evergreens — and an altered flow of nutrients from rapidly decomposing, fallen leaves versus more enduring evergreen needles.
“Everything changes, the microenvironment, the snow and rain that the trees intercept, all kinds of things,” Orwig said. “But forests are resilient, and we often see dense thickets of black birch come in. That’s a different forest, but it will rapidly grow. It may store carbon very quickly but uses water very differently.”
Though Orwig marvels at the forest’s resilience and insists that natural change is neither good nor bad, he still admits he’ll miss the hemlocks at Harvard Forest and in the old-growth forests he studies across New England.
“I love being in a hemlock forest. I like how they smell. I like how they feel when you walk around on the spongy earth,” Orwig said. “And I do feel great loss when we lose vast areas of forest due to an introduced insect. It is painful to see 300- to 400-year-old hemlocks being killed off.”
Others tally generational loss on top of personal concerns. Future generations, they fear, may not even know what they’re missing.
“I can remember being an undergraduate traipsing through these forests, and they are different now, but I don’t know how to convey that,” said Harvard Forest Director Missy Holbrook, the Charles Bullard Professor of Forestry.
Holbrook described a concept called “shifting baselines,” the idea that we each form our own sense of what we consider normal based on personal experience. Coming generations will have a different baseline than we do, Holbrook said. And that can impact everything from the scientific questions that are asked to how conservation programs are designed to what restoration efforts are undertaken.
“If you’ve never experienced an old-growth forest or a hemlock forest, it’s not in your realm of imagination,” Holbrook said. “I remember when we had snowier winters consistently, and my son will not have that frame of reference. So, climate change is affecting me: It affects me when I raise my son and when I teach. And climate change is accelerating, not slowing.”
Nation & World
What exactly is a republic anyway?
Enrollment for “What is a Republic?” has quadrupled since Professor Daniel Carpenter (pictured) last taught the course two years ago.Niles Singer/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
March 4, 2025
6 min read
Government professor looks at long history, evolution of form of governance in class that’s drawing high inter
Enrollment for “What is a Republic?” has quadrupled since Professor Daniel Carpenter (pictured) last taught the course two years ago.
Niles Singer/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
6 min read
Government professor looks at long history, evolution of form of governance in class that’s drawing high interest in current moment
“These peculiar people call themselves republicans.”
Daniel Carpenter, the Allie S. Freed Professor of Government, presented his class with an image of emotional demonstrators waving red, white, and blue flags. Except there were no ruby-red MAGA hats in this contemporary newspaper photo.
“They were gathered, dressed in yellow for maximum visibility, to chant: ‘Not my king!’” Carpenter explained.
These self-styled British republicans, opposed to the 2023 coronation of King Charles III, proved the perfect opening for Carpenter’s spring 2025 “What is a Republic?” The Gen Ed offering, also available online via Harvard Extension School, has struck a chord in the current political moment. Enrollment has quadrupled since Carpenter last taught the course two years ago, with more than 250 in this semester’s class.
“The course description was fascinating because it highlighted that a republic is actually something pretty specific,” said student Michael Zhao ’25, a double concentrator in computer science and government from California. “It’s a system where power flows through representation from the people and is held in public offices rather than by individuals.”
Carpenter’s lectures will culminate with a deep dive into the 18th-century founding, and centuries-long evolution, of America’s particular approach to republican governance as well as a study of the Third and Fifth Republics of France. But first, Carpenter is guiding students through historic iterations of republics and proto-republican systems, with their varied approaches to organizing power — vested in elected and non-elected offices alike.
Many of today’s governing institutions, including Congress and parliaments around the world, owe much to ancient Rome during its republican period (roughly 509 B.C.-27 B.C.). No longer ruled by kings, Roman men were entrusted with electing representatives to various assemblies. The same era saw elected and appointed officeholders charged with managing public resources like infrastructure and tax revenue.
“How to balance responsiveness to popular sovereignty with institutional stability. How to maintain trust in government. How to keep officeholders accountable. These are questions that have challenged republican governments for millennia,” Zhao said.
Even non-representative systems inspired some of the key institutions of modern republics. Medieval Europe saw the first Catholic bishoprics (or dioceses) rising from the ashes of former Roman provinces. These clerical districts did not practice representative government, Carpenter told his students. But the republican state-builders of subsequent ages couldn’t help but copy the complex administrations of the wealthiest bishoprics.
“One way of thinking about European development is to look at where these different bishoprics begin to form,” Carpenter said while referring to a map of Europe in the early sixth century. “It’s a pretty good predictor of where universities are going to pop up. It’s a good predictor of where urbanization will start happening. It’s a good predictor of medieval trade.”
Accountability is a central tenet of any healthy republic, with elections being a crucial check. But one of the earliest innovations in holding power to account was available even to women, the poor, and other marginalized groups by the medieval era.
Carpenter teaches his course in the Harvard Art Museums’ Menschel Hall.
“How do people below the nobility engage in politics?” Carpenter asked. “One of the few, but very lasting, modes of representation is the petition.”
Republican Rome had various practices and venues for raising complaints. But evidence shows petitioning gaining a foothold in what Carpenter called the “hierarchical, profoundly unequal, and decentralized world” of sixth- to 12th-century Europe.
Soon audits and oaths also caught on as additional ways to keep the powerful in check and more responsive. “These institutions also developed heavily in the most advanced bishoprics and cathedral chapters,” the professor noted.
In addition to attending lectures, students in the course attend weekly discussion sections and tackle an ambitious reading list. Week one assignments included the Declaration of Independence and some of the best-known Federalist Papers. Week two found the students immersed in both classic and contemporary histories of ancient Rome — home to one of the longest-lived republics in human history.
“I really appreciate the rigor I’m getting from this course,” said Jack Flanigan ’27, a social studies concentrator from New York City. “His style of teaching is expansive and draws together a lot of different strands of scholarship into one coherent narrative.”
One text that left a big impression was Niccolò Machiavelli’s “Discorsi,” with the Italian Renaissance political philosopher drawing lessons from the gradual rise and less-gradual fall of Rome’s republic.
“Machiavelli wrote about the importance of having a mixed regime,” said Joshua Eneji ’28, a Texas native weighing concentrations in history, literature, and government. “He said you can’t have only one form of government, or it’s bound to fall. It needs to be intertwined with multiple forms of government so that it’s stable.”
It’s been 20 years since Carpenter, an expert on bureaucratic politics and the administrative state, introduced this study of republics. “You get to learn about the separation of powers, the working of assemblies, the importance of offices, and other institutions not necessarily emphasized in other government courses,” said Carpenter, who is now writing a book based on the class.
Interest in the subject has climbed. “Certain things people took for granted for decades or centuries are being destabilized,” the Government Department chair offered in an interview. “So Harvard students want to know: What are these things being destabilized at the moment? How did they first stabilize? And how do they begin to fall apart?”
One thing that can hinder this pursuit, Carpenter told the class, is clinging to ideas formed by the politically charged realities of 21st-century America. His first lecture touched on the “lazy trope,” ubiquitous on social media and within certain think-tanks, that America is a republic, not a democracy — or a democracy, not a republic.
He chalked it up to a mix of partisanship and presentism. “It’s a historical accident that one of our political parties happens to be named Republicans — and the other happens to be named Democrats,” he said. “And of course, neither of those parties were with us at the founding.”
“I beg of you,” he continued, “to let go of your predilections by saying, ‘Oh, I really want this to be a democracy’ or ‘I really want this to be a republic.’ It’s possible that it’s both.”
Photo by Grace DuVal
Campus & Community
Sense of isolation, loss amid Gaza war sparks quest to make all feel welcome
Liz Mineo
Harvard Staff Writer
March 4, 2025
5 min read
Nim Ravid works to end polarization on campus, in multicultural democracies
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
When he was 15, Nim Ravid and his fam
Sense of isolation, loss amid Gaza war sparks quest to make all feel welcome
Liz Mineo
Harvard Staff Writer
5 min read
Nim Ravid works to end polarization on campus, in multicultural democracies
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
When he was 15, Nim Ravid and his family left their native Tel Aviv and made a work-related move to Woodbridge, Conn., for a couple of years. He loved what he found there.
“It was a transformative experience for me,” said Ravid, now a College senior concentrating in economics. “I love the multicultural nature of this place. In this country, you’re surrounded by people who are very diverse and have different opinions. Even within the Jewish community there is massive disagreements … The cultural diversity here was one of the reasons why I wanted to come back.”
When Ravid was accepted into Harvard, he looked forward to experiencing the same exhilaration he felt when he first came to the United States. But things turned out very different. During his first weeks on campus, he learned that some were avoiding him because of his nationality and his stint in Israel’s Defense Forces, where he spent four years of mandatory service and a few months as a spokesperson for the head of the legislative Foreign Affairs and Defense Committee.
After the Oct. 7, 2023, terror attacks, Ravid’s sense of feeling like an outsider grew as tensions on campus mushroomed amid the ongoing protests over the war in Gaza. Many Israeli students experienced shunning and social exclusion inside and outside the classroom, Ravid said.
“I decided to embark on a mission to build spaces on campus that would allow people who share the same values, despite having different beliefs, to come together, hear one another, and learn from each other.”
In addition to isolation, Ravid struggled with devastating loss — three friends attending the Nova Music Festival were killed by Hamas forces. He decided to use his pain “as a fuel for action” to change campus culture and make it more inclusive and welcoming to all. Another motivation, he said, was his dreams for a brighter tomorrow in the Middle East, in which Israelis and Palestinians could live and prosper together.
“During my first days here, I was very excited to share my experience and looked forward to meeting people here to kind of dream together of a better future in the Middle East,” said Ravid.
“After experiencing such a difficult social exclusion, I decided to embark on a mission to build spaces on campus that would allow people who share the same values, despite having different beliefs, to come together, hear one another, and learn from each other. Since then, I’ve been on a quest.”
Ravid’s mission included informal efforts to bring together Jewish and Muslim students, but the tensions between the pro-Palestine and pro-Israel groups made it hard to recruit people willing to sit together and talk.
With help from some professors, Ravid found a few like-minded Arab and Muslim peers who joined his endeavors, and now the group comprises Israeli, Jewish, Muslim, and Arab students. Together, they have hosted private dinners, small dialogue circles, and conversations with speakers from both sides of the conflict. The group decided to make their events private to promote more open participation away from the public eye.
Michael Sandel, Anne T. and Robert M. Bass Professor of Government, who helped moderate some group discussions, praised the students for their attempts to bridge the campus divide. In an email, he recalled the group’s origins and emphasized Ravid’s role.
“In the fraught aftermath of Oct. 7, a number of Harvard students from Israel and from Arab and Muslim countries came together, quietly and informally, to discuss the Israel-Palestinian conflict and ways of building dialogue,” wrote Sandel. “Nim was an impressive leader of this effort. He displayed an ability to bring people together, and to cultivate the ability to listen with sympathy and mutual respect.
“Nim has since broadened his mission of promoting respectful dialogue on the Harvard campus,” Sandel added. “He is a born leader and a force for good — at a time when not only our campuses but also the world needs voices for community, civility, and mutual understanding.”
Ravid sits on the Harvard Presidential Task Force on Combating Antisemitism and Anti-Israeli Bias as one of its two student representatives. He has also been a member of the Intellectual Vitality Initiative, which aims to foster academic freedom, free expression, open inquiry, and civil discourse.
Although Ravid remains committed to his efforts to bring people together, he recognizes it is an uphill battle.
“It’s been tremendously difficult to get people to come to these events, but I’m inspired by some Arab friends who despite immense social pressures still come,” he said. “This initiative is a product of the work of students who are dedicated to creating a better Harvard for all. We want to create a Harvard where no one is treated differently based on their identity, whether it’s race, gender identity, country of origin, or political views.”
After graduation, Ravid said he plans to continue bringing people together, which has become a life mission. Polarization is poised to be the biggest challenge of the next century as democracies become more racially, ethnically, and religiously diverse, he said, and the way to overcome it is by fostering respectful dialogue across differences.
“For a multicultural democracy to function, one of the first pillars is that different people from different communities have to be able to effectively communicate with each other,” said Ravid. “When that cannot happen because one community is shunned, excluded, or not invited to take part in a dialogue, that prevents a multicultural society from operating effectively.”
Ula Jurkunas performs the first CALEC surgery at Mass Eye and Ear.Photo courtesy of MGH
Health
New hope for repairing eye damage once thought untreatable
Stem cell therapy safely restores cornea’s surface in clinical trial
Ryan Jaslow
Mass General Brigham Communications
March 4, 2025
5 min read
A Mass Eye and Ear-led clinical trial of a procedure that took stem cells from a healthy eye an
New hope for repairing eye damage once thought untreatable
Stem cell therapy safely restores cornea’s surface in clinical trial
Ryan Jaslow
Mass General Brigham Communications
5 min read
A Mass Eye and Ear-led clinical trial of a procedure that took stem cells from a healthy eye and transplanted them into a damaged eye safely restored corneal surfaces in 14 patients who were followed for 18 months.
The stem cell treatment for blinding cornea injuries — called cultivated autologous limbal epithelial cells, or CALEC — was developed at Mass Eye and Ear. It consists of removing stem cells from a healthy eye with a biopsy, expanding them into a cellular tissue graft in a novel manufacturing process that takes two to three weeks, and then surgically transplanting the graft into the eye with a damaged cornea.
“Our first trial showed that CALEC was safe and the treatment was possible,” said principal investigator Ula Jurkunas, associate director of the Cornea Service at Mass Eye and Ear and professor of ophthalmology at Harvard Medical School. “Now we have this new data supporting that CALEC is more than 90 percent effective at restoring the cornea’s surface, which makes a meaningful difference in individuals with cornea damage that was considered untreatable.”
The cornea is the clear, outermost layer of the eye. Its outer border, the limbus, contains a large volume of healthy stem cells called limbal epithelial cells, which maintain the eye’s smooth surface.
When a person suffers a cornea injury, such as a chemical burn, infection, or other trauma, it can deplete the limbal epithelial cells, which can never regenerate. The resulting limbal stem cell deficiency renders the eye with a permanently damaged surface where it can’t undergo a corneal transplant, the current standard of care for vision rehabilitation. People with these injuries often experience persistent pain and visual difficulties.
National Eye Institute
This need led Jurkunas and Reza Dana, director of the Cornea Service at Mass Eye and Ear, to explore a new approach for regenerating limbal epithelial cells. Nearly two decades later, following preclinical studies and collaborations with researchers at Dana-Farber and Boston Children’s, it was possible to consistently manufacture CALEC grafts that met stringent quality criteria needed for human transplantation. The clinical trial was approved by the U.S. Food and Drug Administration and Mass General Brigham Institutional Review Board, and the first patient was treated in 2018 at Mass Eye and Ear. Successful completion of the trial was accomplished through close coordination between Jurkunas’ surgical team and the cell manufacturing facility at Dana-Farber.
One limitation of this approach is that it is necessary for the patient to have only one involved eye so a biopsy can be performed to get starting material from the unaffected normal eye.
“Our future hope is to set up an allogeneic manufacturing process starting with limbal stem cells from a normal cadaveric donor eye,” said Jerome Ritz of Dana-Farber Cancer Institute’s Connell and O’Reilly Families Cell Manipulation Core Facility, where the stem cell grafts are manufactured. “This will hopefully expand the use of this approach and make it possible to treat patients who have damage to both eyes.”
Researchers showed the procedure completely restored the cornea in 50 percent of participants at their three-month visit, and that the rate of complete success increased to 79 percent and 77 percent at their 12- and 18-month visits, respectively. With two participants meeting the definition of partial success at 12 and 18 months, the overall success was 93 percent and 92 percent at 12 and 18 months. Three participants received a second transplant, one of whom reached complete success by the end visit. An additional analysis of the procedure’s impact on vision showed varying levels of improvement of visual acuity in all 14 patients.
CALEC displayed a high safety profile, with no serious events in either the donor or recipient eyes. One adverse event, a bacterial infection, occurred in one participant eight months after the transplant, due to chronic contact lens use. Other adverse events were minor and resolved quickly following the procedures.
The procedure remains experimental and is currently not offered at Mass Eye and Ear or any U.S. hospital, and additional studies will be needed before the treatment is submitted for federal approval.
The trial is the first human study of a stem cell therapy to be funded by the National Eye Institute, a part of the National Institutes of Health, and was the first stem cell therapy in the eye in the U.S. Other research collaborators include Jia Yin at Mass Eye and Ear; Myriam Armant of Boston Children’s Hospital; and the JAEB Center for Health Research.
In the interim, future CALEC studies should include larger numbers of patients at multiple centers, with longer follow-ups and a randomized-control design.
“We feel this research warrants additional trials that can help lead toward FDA approval,” said Jurkunas. “While we are proud to have been able to bring a new treatment from the lab bench to clinical trials, our guiding objective was and always will be for patients around the country to have access to this effective treatment.”
This research is funded by National Eye Institute of the National Institutes of Health.
Disclosures: CALEC is patent-pending. Jurkunas and Dana have financial interest in OcuCell, a company developing living ophthalmic cell-based therapies for treating eye disease. Armant serves on the scientific advisory board for OcuCell. Ritz receives research funding from Kite/Gilead, Novartis, and Oncternal, and serves on Scientific Advisory Boards for Astraveus, Garuda Therapeutics, Smart Immune, Tolerance Bio, and TriArm Therapeutics. The remaining authors declare no competing interests.
Health
Cancer? No, thank goodness, it’s just high cholesterol.
Joseph Woo (on screen, from left), Ami Bhatt, Tommaso Danesi, Jorge Plutzky, and Melody Mendez in conversation.Photos by Niles Singer/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
March 3, 2025
6 min read
Cardiovascular disease remains nation’s top cause of death, but patients seem too casual about prevention, experts sa
Cancer? No, thank goodness, it’s just high cholesterol.
Joseph Woo (on screen, from left), Ami Bhatt, Tommaso Danesi, Jorge Plutzky, and Melody Mendez in conversation.
Photos by Niles Singer/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
6 min read
Cardiovascular disease remains nation’s top cause of death, but patients seem too casual about prevention, experts say
Heart disease — America’s No. 1 killer — has a surprising problem, according to cardiovascular disease experts. It’s not scary enough.
“You get a cancer diagnosis, and everybody moves. They move heaven and earth. Families move. People move,” said Ami Bhatt, chief innovation officer at the American College of Cardiology. “You say, ‘heart disease’ and people don’t move in the same way.”
The attitude of many, if not most patients, is that they’ll get to it. They’ll improve their diet after the holidays, and they’ll start that exercise program once the weather warms up. All of this needs to change.
That was the message from Bhatt and other cardiovascular surgeons and experts in heart disease prevention and medical innovation who came together Feb. 26 at the Harvard T.H. Chan School of Public Health to sound a wake-up call.
They pointed out that cardiovascular disease’s continued status as the country’s leading cause of death despite decades of progress means much work remains. There have been dramatic advances in areas such as minimally invasive surgery and transplant surgery, while visions of the near future feature a growing use of artificial intelligence that leverages all of medical knowledge in real time to provide patients increasingly personalized care.
But when it comes to prevention, the prospect of a disease diagnosis tends to elicit only a casual response among patients, leaving those who deal with it daily scratching their heads.
“This happens to me every single week in the clinic when I’m seeing patients,” said Joseph Woo, chair of Stanford Medical School’s Department of Cardiothoracic Surgery and associate director of Stanford’s Cardiovascular Institute. “I try to remind them that cardiovascular disease kills more Americans every year than every single cancer combined, and if they ever heard they had a cancer inside, regardless of how slow-growing a cancer it would be, they would want it out or treated right away.”
“I try to remind them that cardiovascular disease kills more Americans every year than every single cancer combined.”
Joseph Woo
Jorge Plutzky, director of preventative cardiology at Brigham and Women’s Hospital, said the problem may stem from the fact that many aren’t aware that cardiovascular damage isn’t a result of old age but accumulates over decades. He said patients should not wait until they have to be treated but to “know their numbers” — LDL or “bad” cholesterol, blood pressure, weight, and sleep quality — from an early age.
He recalled conversations with patients who view cholesterol-lowering meds skeptically and juxtaposed them with a recent a conversation with a 28-year-old cardiology fellow who decided to start taking statins because his LDL cholesterol, while not high, was not in the optimum range.
“That frames a lot of the challenge for us because what does that cardiology fellow at the Brigham know that that patient doesn’t know?” said Plutzky, an associate professor of medicine at Harvard Medical School. “Bridging that gap is really at the core of effectively communicating what the issue is and why you want to do it. Doctors aren’t initiating a statin early because they think it’s harmful. They’re initiating early because they think there’ll be benefits.”
“Doctors aren’t initiating a statin early because they think it’s harmful. They’re initiating early because they think there’ll be benefits.”
Jorge Plutzky
Last week’s event, “Understanding heart disease: Advances in risk assessment, diagnosis and treatment,” also featured Tommaso Danesi, section chief of valve surgery and director of the Endoscopic Valvular Program at Brigham and Women’s Hospital. The event, a Dr. Lawrence H. and Roberta Cohn Forum, was moderated by Melody Mendez, an anchor and reporter at NBC10 Boston, and hosted by the Chan School’s Leadership Studio.
Panelists discussed a variety of developments in cardiovascular disease care. Perhaps most dramatic is a heart transplant technique that uses a machine to keep the donor heart pumping during transport to the transplantation site rather than being stopped and stored on ice while moving from donor to recipient. The transplant is completed with the heart still beating, which improves patient recovery time.
Endoscopic surgery has also advanced significantly, with heart valve replacement requiring just a three-inch slit and allowing patients to go home after four days. Physical function returns to baseline after just two to three weeks, Danesi said, compared to two to three months with traditional open-heart surgery, in which the entire chest cavity is opened.
Advances have also come in nontraditional areas, Bhatt said. Wearable fitness devices, for example, can be considered a sign of rampant “consumerism” but also can be viewed as a way for patients to gain agency over their health and know at least some of their numbers, a positive development in an area like cardiovascular disease.
Similarly, Bhatt said, the rapidly expanding use of the latest generation of weight-loss medications by patients without a clinical diagnosis has been disparaged as a sign of vanity, but it’s also the case that the drugs — and their associated weight loss — have been associated with improved health.
“Our population is getting healthier,” Bhatt said. “You don’t have to be a full-fledged diabetic with heart failure, or risk, to benefit from GLP-1.”
“Our population is getting healthier. You don’t have to be a full-fledged diabetic with heart failure, or risk, to benefit from GLP-1.”
Ami Bhatt
New drugs, techniques, and technology define the recent past and near future of cardiovascular disease, but age-old problems persist, Plutzky said. Patients routinely skip screenings that could identify problems in advance and, even when prescribed medication, many stop taking it because life’s pressures intervene: They move; their prescription runs out and they can’t get a refill; or they have trouble connecting with a doctor.
One answer Plutzky described is to use “navigators” to augment the care and attention of physicians between office visits. The navigators reach out to patients and provide intermediate follow-up after surgery to implant a stent to keep a blood vessel open, for example, or when a patient is struggling with rising LDL cholesterol levels or blood pressure.
“It’s quite shocking, the extent of undertreatment we find, even in an excellent system like ours,” Plutzky said. “We can immediately say, ‘OK, that prescription is now waiting for you. Here’s the basis for why you want to do that, and let’s get you back into treatment.’”
Plutzky said the approach spares busy doctors the need to address prescription refills — a mundane but important part of the patient’s treatment — provides contact and encouragement to the patient in the months between appointments, and as community-based outreach, helps lower barriers to access.
“This strategy has been extremely effective in terms of getting people into the right treatment,” Plutzky said. “It doesn’t rely on education, affluence, or other things. It simply says this person’s LDL is very high, they should be on treatment, and we can get that initiated in a fairly simple and effective way.”
Science & Tech
Exploring superconducting electrons in twisted graphene
Could up the game of lossless power transmission, levitating trains, quantum computing, even energy-efficient detectors for space exploration
Clea Simon
Harvard Correspondent
March 3, 2025
4 min read
Abhishek Banerjee (from left), Philip Kim, and Zeyu Hao. Veasey Conway/Harvard Staff Photographer
Superconductors, m
Exploring superconducting electrons in twisted graphene
Could up the game of lossless power transmission, levitating trains, quantum computing, even energy-efficient detectors for space exploration
Clea Simon
Harvard Correspondent
4 min read
Abhishek Banerjee (from left), Philip Kim, and Zeyu Hao.
Veasey Conway/Harvard Staff Photographer
Superconductors, materials that can transmit electricity without resistance, have fascinated physicists for over a century. First discovered in 1911 by Dutch physicist Heike Kamerlingh Onnes, who observed the phenomenon in solid mercury cooled with liquid helium to around minus 450 F (just a few degrees above absolute zero), superconductors have been sought to revolutionize lossless power transmission, levitating trains, and even quantum computing.
Now, using specially developed microwave technology, a team of researchers from Harvard, Massachusetts Institute of Technology, and Raytheon-BBN Technologies has revealed unusual superconducting behavior in twisted stacks of graphene, a single atomic layer of carbon. Their research was published in Nature.
Graphene was discovered in 2004 by Andre Geim and Konstantin Novoselov, earning them the Nobel Prize in physics a few years later. In 2018, an MIT team led by Professor Pablo Jarillo-Herrero, one of the authors of the new paper, discovered superconductivity in a stack of twisted bilayer graphene.
“This seminal work showed that a small twist between two layers of graphene can create drastically different properties than just a single layer, and since then, scientists have also found that adding more layers of graphene with a small twist can lead to similar superconducting behavior,” said Zeyu Hao, a Ph.D. student in the Kenneth C. Griffin Graduate School of Arts and Sciences working in the Kim Group lab at Harvard and one of the paper’s co-lead authors. The researchers’ most striking finding is that the superconducting behavior of electrons in twisted stacks of graphene differs from conventional superconductors such as aluminum. That difference “calls for careful studies of how these electrons move in sync — this ‘quantum dance’ — at very low temperatures,” Hao said.
Understanding why electrons pair up instead of repelling each other, as they naturally do due to their negative charge, is the key to uncovering how superconductivity arises. “Once electrons pair strongly enough, they condense into a superfluid that flows without losing energy,” said Abhishek Banerjee, co-lead author of the paper and a postdoctoral fellow in the Kim group. “In twisted graphene, electrons slow down, and the interaction between them somehow mixes with quantum mechanics in a bizarre way to create a ‘glue’ force that binds them in pairs. We still don’t fully understand how this pairing works in this new class of superconductors, which is why we’re developing new ways to probe it.”
One such approach is to measure the resonant vibration of the superconducting electrons — a “superfluid” of paired electrons — by illuminating them with microwaves, which is a bit like “listening to the tune” of the superfluid, said Mary Kreidel, co-lead author of the paper who worked with Mallinckrodt Professor of Applied Physics and of Physics Robert Westervelt at Harvard and Kin Chung Fong at Raytheon BBN Technology.
“It’s similar to playing a glass harp,” said Hao. “Instead of blowing over bottles filled with varying amounts of water to produce different notes, we use a microwave circuit as the ‘bottle,’ and the ‘water’ is the superfluid of paired electrons. When the amount of superfluid changes, the resonant frequency shifts accordingly. Essentially, we’ve made our glass bottles using this microwave resonant circuit, and the water is basically the electrons paired up to condense into a superfluid, where the electrons can flow without losing energy.”
“When the weight and volume of the superfluid — essentially the density of paired electrons—changes, so does the musical tone,” said Kreidel.
From these frequency shifts, the team observed unexpected clues about how these electrons might be pairing up. “We learned that the adhesive force between electrons can be strong in some directions and vanish in others,” said Ph.D. student Patrick Ledwith, who works at Harvard with George Vasmer Leverett Professor of Physics Ashvin Vishwanath. This directionality resembles what’s seen in high-temperature superconductors made from oxide materials — still a puzzle to scientists, even after 40 years of study. “Perhaps our findings with twisted graphene can shed light on how electrons perform this quantum dance in other two-dimensional superconducting materials,” said Professor of Physics and Applied Physics Philip Kim, the lead scientist on this work.
While graphene technologies can’t yet be mass-produced, the researchers see wide-ranging potential. Kreidel, now a postdoc at NASA’s Jet Propulsion Laboratory, points out that such materials could help build ultrasensitive, energy-efficient detectors for space exploration. “In the near vacuum of space, there’s very little light,” she said. “We want small, lightweight detectors that use minimal power but have extremely high resolution. Twisted graphene may be a promising candidate.”
This project was supported, in part, by the U.S. Department of Energy and the National Science Foundation.
Moderator Jonathan Zittrain (from left) and Anupam Chander listen as Alan Rozenshtein (far right) shares concerns about TikTok and its potential threat to national security.Veasey Conway/Harvard Staff Photographer
Nation & World
Did the TikTok ban go too far?
Law School debate examines potential national security threat, 75-day extension issued by Trump
Liz Mineo
Harvard Staff Writer
February 28, 2025
5
Moderator Jonathan Zittrain (from left) and Anupam Chander listen as Alan Rozenshtein (far right) shares concerns about TikTok and its potential threat to national security.
Law School debate examines potential national security threat, 75-day extension issued by Trump
Liz Mineo
Harvard Staff Writer
5 min read
There may be no smoking gun yet, says law Professor Alan Rozenshtein about the potential national security threat posed by the social media app TikTok, “but the gun is assembled, it’s loaded, it’s on the table, and it’s pointed. You’re much closer to this nightmare scenario than you might expect.”
Rozenshtein, who teaches at the University of Minnesota Law School, spoke at a Harvard Law School event Monday with Anupam Chander, Georgetown Law professor. The two debated the U.S. law requiring ByteDance, TikTok’s Beijing-based parent, to sell the app to a U.S. firm or face a nationwide ban, and the 75-day extension granted ByteDance by President Trump, which will run out on April 5.
Rozenshtein felt it was far from perfect but generally supported the law Congress passed last year, noting that TikTok, which specializes in playing personalized series of short videos, could harvest a huge amount of information on its 170 million American users for counterintelligence purposes. And the Chinese government, through ByteDance, could pressure TikTok, which is algorithmically driven, to modify its algorithms in ways that would be adverse to America’s interests, he added.
“Imagine that the United States and China get into a shooting war over Taiwan,” said Rozenshtein. “Suddenly the concern would be that TikTok would be flooded with pro-Chinese, anti-Taiwan and anti-American content. Given that TikTok is not only very popular, but for young Americans, it is increasingly the main source of news, that’s very concerning.”
On the other side of the debate, Chander criticized the TikTok law because of its speculative nature and potential First Amendment violations. In its suit against the law, TikTok claimed it violated the First Amendment’s speech protections. The Supreme Court rebuked TikTok’s claims in a ruling on Jan. 17, two days before the ban was to go into effect.
“In Professor Rozenshtein’s description, the problem was all speculative,” said Chander. “It was the possibility that we might get into a shooting war. They might then use the app to manipulate us in favor of China, neglecting our sense of patriotism, undermining democracy, etc., or they might convince us that Taiwan is really Chinese and therefore should properly belong to China, which are the kinds of highly speculative things that First Amendment law typically has not tolerated.”
Chander and Rozenshtein pondered the possibility of another extension to give TikTok more time to find a way to comply with the law.
Chander said Trump could use the International Emergency Economic Powers Act (IEEPA), a federal law that allows the president to regulate international commerce during a national emergency triggered by a foreign threat.
“If I were in the White House Counsel’s Office, I would use IEEPA,” said Chander. “I would say, ‘You have to keep the lights on TikTok because otherwise people will move to RedNote.’”
RedNote, another Chinese social media platform, saw an increase of American users in the wake of the TikTok ban. According to experts, RedNote could pose more security risks than TikTok because RedNote stores its data in Chinese servers, unlike TikTok, which stores American users’ data in Texas. And RedNote gets closer scrutiny from the Chinese government, being subject to censorship efforts — TikTok says it is not.
The two social-media apps, however, are not alike. TikTok specializes in entertainment and instructional video and viral cultural trends, and RedNote, which started as a shopping platform, focuses on user tips on travel, makeup, fashion, and shopping.
Asked about the possibility of a one-year extension, Rozenshtein expressed concerns about the overreach of executive power. “If we have learned anything, it is that the one-way ratchet of executive power and the ability to rewrite laws has some serious downsides,” he said.
Both Chander and Rozenshtein agreed that the U.S. government should have addressed national security concerns over TikTok a while ago and not after it became widely popular. They shared concerns about the quick way Congress approved the TikTok law after several years of inactivity.
“The Biden administration had the power to require divestiture of TikTok since it came to office,” said Chander. “It stopped negotiating the mitigation arrangement with TikTok in August 2022. The administration had that power for years and sat on it.”
Chander said that the TikTok bill was motivated by concerns over espionage and propaganda, but citing the words of former Republican Rep. Mike Gallagher of Wisconsin, who co-sponsored the bill, said “the greater concern was about the propaganda threat.”
As for the bill’s approval, Chander cited comments by Gallagher, who said that the Oct. 7 Hamas-led attacks on Israel, followed by the proliferation of pro-Palestinian views and antisemitic content on the platform, helped the bill pass with bipartisan support in March 2024.
For Rozenshtein, even if critics argue there is no evidence of TikTok’s content manipulation, the threat is real. Even if the law has flaws, it was the best thing that the U.S. could do, he said.
Eric Klinenberg.Photos by Veasey Conway/Harvard Staff Photographer
Nation & World
We’re already forgetting what 2020 was like
5 years later, sociologist urges us to confront lessons from pandemic
Anna Lamb
Harvard Staff Writer
February 28, 2025
4 min read
In 2020, signs and social media posts praising essential workers were ubiquitous. Now, you hardly ever hear talk about the people w
5 years later, sociologist urges us to confront lessons from pandemic
Anna Lamb
Harvard Staff Writer
4 min read
In 2020, signs and social media posts praising essential workers were ubiquitous. Now, you hardly ever hear talk about the people who put themselves at risk to keep the country going during the pandemic. In his book “2020: One City, Seven People, and the Year Everything Changed,” sociologist Eric Klinenberg reminds readers not to be so quick to forget how the pandemic changed us and the impacts we’re still dealing with today.
Klinenberg brought this conversation to Harvard Law School’s Petrie-Flom Center, where he was joined in a panel discussion by Rochelle Walensky, the former director of the Centers for Disease Control and Prevention; Professor I. Glenn Cohen, the faculty director of the Petrie-Flom Center for Health Law Policy, Biotechnology & Bioethics; and Professor Jeannie Suk Gersen, the John H. Watson Jr. Professor of Law at Harvard Law School.
“So many things happened so fast in 2020 and it’s been hard for us to grab them all.”
Eric Klinenberg
“So many things happened so fast in 2020 and it’s been hard for us to grab them all,” Klinenberg said. “We’re in such denial, we’re in a rush to move on, we’re forgetting what it was like to live through that dysfunction, that dysregulation. We’re forgetting about the deaths we incurred.”
Klinenberg’s book flashes between in-depth profiles of individuals across the seven boroughs of New York City and sociological analysis of the pandemic. It explores the inequalities that were exacerbated by the crisis, including for low-income families and kids in the Bronx who struggled to access remote learning or replace the free and reduced school lunches on which they relied.
It also explores the ways in which the pandemic eroded our trust in leaders. In one chapter, Klinenberg tells the story of a family whose daycare didn’t inform them of its reopening out of fear of contracting COVID from the child of an essential worker. In another, he focuses on Daniel Presti, a Staten Island bar owner who refused to close his doors in late 2020. Presti was radicalized after feeling the federal government wasn’t doing enough to protect business owners struggling in the wake of lockdown rules.
“I think one of the issues around trust and distrust that we need to talk more about is we’re living in different information environments, and I think there are growing concerns that vital statistics that we need to make sense of who we are and what’s happening, what might happen next, are becoming harder to trust and control,” Klinenberg said in the panel discussion.
Panelists Jeannie Suk Gersen (from left), I. Glenn Cohen, Klinenberg, and Rochelle Walensky.
Walensky, who was tasked with making recommendations to protect public health during her CDC tenure, spoke to Klinenberg’s portrayal of the tradeoffs that decision-makers like herself had to make. She remembered a school board meeting in her hometown of Newton, Massachusetts, where a mother said she was being asked to respect coronavirus policies at the cost of her son’s future.
“She said, ‘If my son doesn’t wrestle next semester, he’s not going to college,” Walensky said. “And then all of a sudden, health is just one thing at the table, and there are really other poignant, important considerations that when we are monocular on health and health alone, we are not considering for the long-term health of a society.”
She added that as a public health official, the costs of infectious diseases are always disproportionate to the vulnerable.
“I remember being on CNN at one point, when the president got COVID. And they were talking about all the famous people in the White House … who [were] infected in the Rose Garden, in the Senate. And I thought to myself, and I said out loud, actually, ‘What about the butlers and the workers in the White House who are going home to multigenerational families who, when you say words like isolation and quarantine, you know they have no capacity to do what you’re asking of them?’”
Klinenberg ends his book as he began the talk — urging people not to move on too quickly from a life-changing event.
“Although the calendar has turned,” he writes, “the story of 2020 is far from over, and its potential to move us in different directions is not yet tapped dry.”
Klinenberg is the Helen Gould Shepard Professor in Social Science and director of the Institute for Public Knowledge at New York University.
Musa al-Gharbi (left) and moderator Ryan Enos.Stephanie Mitchell/Harvard Staff Photographer
Nation & World
Think top 1% benefit most from U.S. inequity? Maybe not.
Book by Musa al-Gharbi argues left-leaning knowledge workers in education, law, media voice support of social justice but have conflicts of interest
Christy DeSmith
Harvard Staff Writer
February 28, 2025
5 min read
Who bene
Think top 1% benefit most from U.S. inequity? Maybe not.
Book by Musa al-Gharbi argues left-leaning knowledge workers in education, law, media voice support of social justice but have conflicts of interest
Christy DeSmith
Harvard Staff Writer
5 min read
Who benefits most from inequality in the U.S. today? According to Musa al-Gharbi, it’s the very people most likely to identify as anti-racist, feminist, and LGBTQ+ allies.
Al-Gharbi, a Stony Brook University journalism professor, outlined key arguments from his “We Have Never Been Woke: The Cultural Contradictions of a New Elite,” in a campus appearance earlier this month. The 2024 book holds that the 21st century’s left-leaning knowledge workers are sincere in their commitment to social justice. They just don’t acknowledge how those beliefs conflict with others they hold dear.
“We also think that our perspectives should count more than the person checking us out at Stop & Shop,” argued al-Gharbi, who earned his sociology Ph.D. from Columbia University in 2023. “We think we should have a higher standard of living than the people delivering packages to our doorsteps. And what’s more, we want our children to reproduce our own social position or to do even better than us.”
The “we” in the book’s title, al-Gharbi said, pertains to a subset of Americans he calls “symbolic capitalists.” The term, borrowed from the work of French sociologist Pierre Bourdieu, refers to people working in fields like human resources, education, finance, law, and media.
“As a shorthand, you can think of people who don’t provide physical goods and services,” al-Gharbi said. “If you’re in this room, chances are you’re a symbolic capitalist — or aspiring to be one.”
“We think that our perspectives should count more than the person checking us out at Stop & Shop. We think we should have a higher standard of living than the people delivering packages to our doorsteps.”
The 21st century brought a shift in how these highly educated, mostly white professionals talk about race, gender, and sexuality, he said. The book uncovers a historic cycle of similar trends, including the “politically correct” fever of the late 1980s and early ’90s. Origins of the so-called “Great Awokening,” as al-Gharbi calls it, are situated in the Occupy Wall Street movement of the early 2010s, with its famous “We are the 99 percent” mantra.
Many in this last group are symbolic capitalists who profit handsomely off the superrich, he said. “Are the billionaires drafting their own PR to help absolve themselves of blame and paint themselves as solutions? Are they doing their own legal paperwork and moving the money around?” asked al-Gharbi.
Add to that the expert analyses employed in areas from court cases to news coverage, for a fuller picture of the group’s cultural primacy — and outsize influence. Symbolic capitalists also dominate all three branches of the federal government, with 100 percent of the judiciary, about 70 percent of the House, and more than 90 percent of the Senate, al-Gharbi pointed out.
“Here’s a fun fact,” he said. “Every single Democrat who’s won the White House since Jimmy Carter has been one variety of symbolic capitalist: a lawyer.”
“We Have Never Been Woke” opens with al-Gharbi’s first impressions of New York’s “racialized caste system” after moving from his conservative Arizona hometown in 2016.
“You have disposable servants who will clean your house, watch your kids, walk your dogs, deliver prepared meals to you,” he writes. “It’s mostly minorities and immigrants from particular racial and ethnic backgrounds who fill these roles, while people from other racial and ethnic backgrounds are the ones being served.”
So why don’t members of the latter group see themselves as elites? “A lot of our professions are explicitly oriented around holding the elites to account,” al-Gharbi explained. But researchers have found those within these fields perpetuate a form of credential inflation to protect their own status while excluding outsiders.
Using journalism as an example, al-Gharbi noted the high number of Ivy League graduates currently working at prestigious outlets like The New York Times. “This matters,” he said. “Because if the elites you’re supposed to be holding to account are your classmates from Harvard, or your neighbors, or your former lovers, then that radically changes how you go about the job.”
“Woke” discourse is an additional tool symbolic capitalists can use to advance their interests, al-Gharbi argued. Affluent suburban and urban professionals wield “mocking, censoring, and deriding” language not only to morally justify their own privilege. They use it to paint some of America’s most disadvantaged as undeserving racists, sexists, and homophobes.
“And this kind of behavior creates an opening for political entrepreneurs, usually associated with the right,” he concluded, with “political correctness” following a trajectory similar to the “woke” backlash unfolding today.
“We haven’t really tried persuasion,” answered al-Gharbi, who writes for publications including the Guardian and the American Conservative. “If I want to convince people that, say, bombing Syria is a bad idea, it doesn’t do a lot of good to write in an outlet like Al Jazeera where everyone already agrees. You need to go to the people who want to bomb Syria and explain to them why that’s a bad idea in a way they will find persuasive.”
Illustrations by Liz Zonarich/Harvard Staff
Health
How much sleep do you need?
And what you can do to get it
February 28, 2025
3 min read
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
Elizabeth Klerman is a sleep researcher and a professor of neurology.
It varies by person. Generally, it’s how much you
A series of random questions answered by Harvard experts.
Elizabeth Klerman is a sleep researcher and a professor of neurology.
It varies by person. Generally, it’s how much you get if you don’t have an alarm clock or someone to wake you up. See how much sleep you are getting after three or four days when no one wakes you and you don’t quickly get out of bed after you wake up (so you may fall back asleep). That might be how much you “need.” You can’t sleep unless you need to, not even when you’re bored — unlike eating chocolate cake, which you can do when you’re not hungry.
“Our body takes a while to figure out it’s time to go to bed. If you remember when you were a kid, you got a bath, you read a book, and the lights were low. The kid’s body says, “Now I know it’s time to go to sleep.”’
If you wake up and you’re not feeling rested, even after several nights of eight hours of sleep, you should consider seeing a sleep doctor. Not feeling rested could signal everything from narcolepsy to hypersomnia to sleep apnea. I’m not talking about how rested you feel the minute you wake up. Different parts of your brain wake up at different rates, so it’s not expected that you immediately feel totally alert. See a doctor if you’re waking up in the middle of the night or if your bed partner complains that you’re snoring loudly or that you’re kicking a lot.
Not everybody can get all the sleep they want at night. If you can take a nap, especially if you’re working the night shift, that’s good.
If you’re having problems falling asleep, don’t watch a horror movie before bed. No caffeine beforehand. Your body takes a while to figure out it’s time to go to bed. If you remember when you were a kid, you got a bath, you read a book, and the lights were low. The kid’s body says, “Now I know it’s time to go to sleep.” So when people are having problems going to sleep, we sometimes suggest doing something calming before getting into bed.
Melatonin is not regulated by the FDA. It’s a supplement, so you don’t know if what’s on the bottle is what you’re getting. I cannot suggest that people take melatonin unless they get pharmaceutical-grade. Other drugs, like more conventional sleeping pills, such as benzodiazepines, are not supposed to be taken long-term. They’re short-term solutions for a particular stressor.
For insomnia, long-term cognitive behavioral therapy is the way to go. As for sleep podcasts or sound machines, if that’s what works for people, I’m not going to object, especially if the sound turns off after a little while. Eye masks and earplugs, as long as they don’t block out something like a fire alarm, are fine with me.
David Lynch in 2004.Photo by Gilles Mingasson/Gettty Image
Arts & Culture
Decoding David Lynch’s ‘familiar yet strange’ cinematic language
Sarah Lamodi
Harvard Correspondent
February 27, 2025
7 min read
Film Archive pays tribute with 3 films that ‘need to be seen on the big screen’
Last month, news of legendary filmmaker and artist David Lynch’s death rocked the film world. Lynch’s e
Decoding David Lynch’s ‘familiar yet strange’ cinematic language
Sarah Lamodi
Harvard Correspondent
7 min read
Film Archive pays tribute with 3 films that ‘need to be seen on the big screen’
Last month, news of legendary filmmaker and artist David Lynch’s death rocked the film world. Lynch’s enigmatic feature films, such as “Blue Velvet” and “Mulholland Drive,” and his television epic “Twin Peaks” challenged viewers during their initial releases and continue to inspire critics, writers, and artists.
This weekend, the Harvard Film Archive will commemorate Lynch’s legacy with a series of three films spanning his career. Sabrina Sutherland, a producer who had worked with Lynch since the 1990s, will present the screenings and participate in a conversation about “Twin Peaks” and its controversial prequel.
Ahead of the series, we asked Film Archive Director Haden Guest to speak to Lynch’s effect on moviemaking, and why we keep returning to his strange, yet familiar, world. This interview has been edited for clarity and length.
Most of Lynch’s work is unexpected and even unnerving, but audiences keep coming back for more. Why do you think that is?
Lynch’s films have remarkable cross-generational appeal; younger audience members are equally as invested as older audience members. Our calendar was already printed, and we’d already announced the screenings before his sudden death in January. What’s remarkable is our screenings were immediately sold out, and they would have been at any time in the past years. His films are so incredibly entertaining, aesthetically rich, absolutely beautiful, and yet at the same time, dark, gripping and even frightening. In Lynch’s films we find a rare, unmatched mixture of polar qualities; of naivete and terror, beauty and abhorrent violence, that we encounter in the art of such figures as Francis Bacon, Kōno Taeko, or Sylvia Plath. This makes Lynch one of the great American filmmakers of the late 20th and early 21st century, without a doubt.
Lynch is able to unleash and to embrace cinema’s potential to explore the uncanny, that thing Freud defined as both familiar and strange. In “Blue Velvet,” for example, the setting is a small town that seems to be this white-picket-fenced, small-town America that is revealed to be shaped by dark, sinister forces lying not just in its shadows, but in full daylight. I remember seeing “Blue Velvet” in a multiplex theater when I was 16 years old, too young for sure, and people were just shocked. They did not know what they were seeing. I remember people being quite upset, others laughing hilariously. And at that time, I was also confused. It’s quite a dark, violent, and psychosexually intense film. But it shaped my imagination and is one of the reasons I am where I am now, teaching film history and curating the HFA cinematheque. I just screened “Blue Velvet” in a course I am teaching, “The Art of Film,” the introduction to cinema for my department, Art, Film and Visual Studies.
Lynch is comparable to another legendary filmmaker, Luis Buñuel, whose films also still retain the power to shock, surprise and delight audiences because of their audacity, and singular approach to image and narrative and sound. There are few filmmakers whose work retains such energy and ability to speak directly to the viewers, to grab them by the shoulders and look right into their eyes. Like Buñuel, I don’t think that Lynch’s power has diminished at all. If anything, it’s grown stronger.
We can’t forget that Lynch is equally important for television. “Twin Peaks” is perhaps one of the most influential television shows of all time. There have been so many attempts made, rarely successful, to make television more cinematic. Lynch is one who understood how to do that, because of his understanding of the limits and possibilities of television, and his deep understanding of and fascination with Americana which came, partially, from his childhood in rural 1950s America. I don’t think it would be a stretch to say that, with “Twin Peaks,” he brought to the mainstream a kind of narrative complexity and mystery that had never been done before.
Lobby cards for (from left) “Eraserhead” and “Wild at Heart” and a still from “Fire Walk With Me.”
Courtesy of the Harvard Film Archive
Why screen “Eraserhead,” “Fire Walk With Me,” and “Wild at Heart,” out of all of Lynch’s films?
We have beautiful vintage 35 mm prints of all three titles — plus a number of other Lynch films — in the HFA collection. Seeing these films on 35 mm is a rare, I would even say revelatory, experience that our audience understands and appreciates. The black and white in “Eraserhead” is incredibly sensual. It’s richly textured, it makes expressive use of shadows and smoke and dark, dank places. These are films that need to be seen on the big screen and with an audience.
I also like the idea of having films from different periods of Lynch’s career. It’s fascinating to see elements from “Twin Peaks” already vivid in “Eraserhead.” The iconic patterned “waiting room” floor, for example, comes from that early film. The films screening this weekend share a dreamlike quality that makes them incredibly captivating and allows them to follow a logic entirely of their own. It allows the audience to let go, perhaps, of expectations they have about what a film should be.
What does it mean to have lost someone like David Lynch?
Lynch is of the same, rarely attained stature of a filmmaker like Alfred Hitchcock, Agnès Varda, Robert Bresson, or Ozu Yasujirō in the sense that he is recognized and celebrated not only as a filmmaker, but as a persona whose visionary art is understood to be a direct expression of his world view. “Lynchian” became a term unto itself — like how you would say something is “Hitchcockian.” There are few filmmakers whose sensibility was so recognizable and influential that it was understood that they’d invented a language of cinema that was entirely their own. That’s a pretty high bar, right? There are very few filmmakers who’ve done that in uncompromising ways without just recycling old tricks; they’re actually doing something new.
“His films created this world that was so uniquely his own. He invented and inhabited it through his uniquely dedicated practice. Which came first, I don’t know.”
Lynch started as a painter and as a sculptor, and I feel like it was that sensibility, the idea of creating a world of one’s own — starting on a canvas of the size and shape that you choose — that was the same with his cinema. His films created this world that was so uniquely his own. He invented and inhabited it through his uniquely dedicated practice. Which came first, I don’t know. All those special elements came together to forge his unique cinematic imagination.
Writing on Lynch tends to be pretty much limited to close readings of his films, and I think there’s a lot more to be said. It’s terrible that he’s no longer with us, but with that comes the sense that we need to reassess his work. How we do that is something I’m really looking forward to, and it starts this week with the HFA screenings.
Campus & Community
4 things we learned this week
Sy Boles
Harvard Staff Writer
February 27, 2025
1 min read
How closely have you been following the Gazette? Take our quiz to find out.
Lots of women don’t trust AI. An orange a day might stave off the psychiatrist. One thing everyone should know about heart disease. More choice isn’t always a good thing. Take our news quiz to see how
How closely have you been following the Gazette? Take our quiz to find out.
Lots of women don’t trust AI. An orange a day might stave off the psychiatrist. One thing everyone should know about heart disease. More choice isn’t always a good thing. Take our news quiz to see how much you learned from the Gazette this week.
Abraham Verghese. Photo by Christopher Michel
Campus & Community
Abraham Verghese, physician and bestselling author, named Commencement speaker
Stanford professor to deliver principal address May 29
February 27, 2025
4 min read
Abraham Verghese, bestselling author, Stanford professor, and infectious disease doctor, will be the principal speaker at Harvard’s 374th Commencement on May 29.
“Througho
Abraham Verghese, physician and bestselling author, named Commencement speaker
Stanford professor to deliver principal address May 29
4 min read
Abraham Verghese, bestselling author, Stanford professor, and infectious disease doctor, will be the principal speaker at Harvard’s 374th Commencement on May 29.
“Throughout his remarkable career, Dr. Abraham Verghese has followed his wide-ranging interests to carve a unique path distinguished by breathtaking creativity, outstanding achievement, and exemplary service and leadership,” said President Alan M. Garber. “He has pursued excellence across disciplines with an intensity surpassed only by his humanity, which shines brilliantly through his works of both fiction and nonfiction, as well as his work as a clinician and teacher. I count myself among his legion of admirers, and I cannot imagine a better individual to inspire the members of our Class of 2025 as they contemplate their futures.”
Verghese is the Linda R. Meier and Joan F. Lane Provostial Professor of Medicine in the Department of Medicine at Stanford University. Devoted to humanizing the physician-patient relationship, he is the founder of Presence, an interdisciplinary center at Stanford focused on championing the human experience in medicine. He’s also the founder of the Stanford Medicine 25, an initiative designed to foster bedside exam skills for learners and for medical professionals. Learning to “read the body,” as Verghese describes it, not only allows physicians to recognize phenotypic information that is before them but also serves as an important ritual that enhances the doctor-patient relationship. Verghese has devoted his academic career to teaching the next generation of physicians the critical importance of empathy, human connection, and compassion in healthcare.
In addition to his work as professor and physician, Verghese is an acclaimed writer. His first book, “My Own Country,” a memoir about his experience caring for patients in a rural community at the dawn of the AIDS epidemic, was a 1994 National Book Critics Circle Award finalist and a Time magazine best book of the year. His second memoir, “The Tennis Partner,” was a New York Times notable book. In 2009, he published “Cutting for Stone,” a novel that spent two years on the New York Times bestseller list and was picked as one of Amazon’s “100 Books to Read in a Lifetime.” In 2023, he published “The Covenant of Water,” a New York Times bestseller and Oprah’s Book Club selection that Netflix is adapting for an upcoming series. In addition to his memoirs and novels, Verghese’s work has been published in The Atlantic, The New Yorker, The New York Times, The Wall Street Journal, and elsewhere.
Verghese was born in Addis Ababa, Ethiopia, to Indian parents, both of whom were teachers. He completed his medical education in India at Madras Medical College. He moved to the United States to complete his medical residency at East Tennessee State University. Following a fellowship in infectious diseases at the Boston University School of Medicine, he returned to East Tennessee State as assistant professor of medicine and special fellow in pulmonary diseases.
In the early 1990s, he took time off from medicine to earn an M.F.A. at the Iowa Writers’ Workshop. After Iowa, he returned to academia as professor of medicine and chief of the Division of Infectious Diseases at Texas Tech University Health Sciences Center, El Paso, and published his first book. He went on to become the founding director of the Center for Medical Humanities and Ethics at the University of Texas Health Science Center, San Antonio, before moving to Stanford in 2007.
Verghese received the Heinz Award for outstanding contribution to arts and humanities in 2014. In 2016, he was awarded the National Humanities Medal by President Barack Obama for his focus on patient-centered healthcare and for contributing to the nation’s understanding of the humanities. He is an elected member of the National Academy of Medicine and the American Academy of Arts and Sciences.
Verghese will receive an honorary degree during the Commencement ceremony in Tercentenary Theatre.
Campus & Community
Student-led projects tackle campus divisions
Students walk across the Weeks Bridge, which connects Harvard’s Cambridge and Allston campuses.Harvard file photo
February 26, 2025
5 min read
Presidential initiative backs efforts to encourage, facilitate constructive dialogue
Through meals, discussion, and games, four student-led projects will kick off this spring in hopes of convenin
Students walk across the Weeks Bridge, which connects Harvard’s Cambridge and Allston campuses.
Harvard file photo
5 min read
Presidential initiative backs efforts to encourage, facilitate constructive dialogue
Through meals, discussion, and games, four student-led projects will kick off this spring in hopes of convening students from different backgrounds and viewpoints to encourage tough conversations and bridge divides.
The projects are funded by the President’s Building Bridges Fund. The initiative, launched in the fall, sought projects focused on building community across faiths, cultures, and backgrounds.
“I am inspired by the passion and creativity our students bring to fostering dialogue across difference,” said President Alan M. Garber. “Changing our culture is a bold but achievable goal that will require sustained effort throughout the University. This first round of projects represents an important step toward realizing our ambition to enable each person at Harvard to explore contested terrain as readily as common ground and to create meaningful connections that lead to intellectual, personal, and social growth.”
The four awarded projects are focused on cultivating conditions for difficult conversations. Some projects will bring students together in small groups to discuss issues of policy and religious law, while others are designed to challenge participants’ worldviews. The goal: create space for dialogue on complex issues and topics outside of the classroom.
“We are pleased to have received so many thoughtful proposals from both undergraduate and graduate students across the University,” said Sherri Charleston, chief diversity and inclusion officer. “The projects selected brought the mission and purpose of the President’s Building Bridges Fund to life in ways that we are confident will have a real impact on our campus this spring.”
Summaries of the projects
Building Understanding Between the Jewish and Muslim Communities at HLS (Harvard Law School)
Laying the foundation for future events and informal opportunities, Jewish and Muslim student leaders at HLS will host a luncheon forum open to all students titled “Linked Traditions: Islamic and Judaic Law.” The event will feature a Jewish and Muslim faculty member (or graduate student) who will engage in a substantive discussion on the two linked legal traditions, as well as explore sources of law, institutional frameworks, and modern issues in each tradition.
Questions Left Unanswered (Harvard College)
This weekly dinner and small group discussion series will bring together College students from diverse intellectual and cultural backgrounds. Over the course of 10 sessions, students will focus on major modern controversies, bringing together students with opposing views for thoughtful small-group discussions about difficult topics. Each session will feature a leading thinker in the field, who will be invited to guide the discussion. By combining intellectual rigor with community-building, this initiative aims to foster a deeper sense of empathy, understanding, and collaboration among participants.
Fostering Intergroup Collaboration and Intellectual Vitality Through a Cooperative Online Quiz Game at Harvard (Harvard Kenneth C. Griffin Graduate School of Arts and Sciences – Psychology)
Through Tango, a cooperative online quiz game grounded in realistic conflict theory and intergroup contact theory, this initiative will offer opportunities to examine the challenges of polarization and tribalism. Designed to foster mutually beneficial cooperation, Tango pairs participants from diverse backgrounds in a collaborative problem-solving environment. The questions asked are designed to challenge participants’ worldviews and create meaningful intergroup discussion, thus reducing outgroup animosity and promoting mutual respect across lines of division.
Policy Bridges: Fostering Constructive Dialogue Across Ideological Divides (Harvard Griffin GSAS – Biological Sciences in Public Health, HSPH, and Biomedical Informatics, HMS)
This three-panel discussion series will focus on a pressing policy issue for the 21st century (Climate Policy, Technology Policy, and Health Policy). The sessions will include small and large discussion groups where both the audience and the experts jointly discuss and identify the common ground and shared values that inform each perspective represented. The goal of the work is to provide a space to facilitate constructive conversations that help bridge ideological gaps, promote mutual understanding, and identify common ground on pressing policy matters.
Building relationships between affinity groups whose interests and views on important issues might diverge
Investing in intellectual excellence
Acting against discrimination, bullying, harassment, and hate
Fostering constructive dialogue on campus about interfaith issues, intercultural issues, or some combination of the two
“Both task forces recognized the importance of providing opportunities for students to build cross-cutting community outside of the classroom and to learn skills around constructive dialogue,” said Danielle Allen, James Bryant Conant University Professor, and a member of both Presidential Task Forces. “These projects respond to the recommendations of the task forces by providing those opportunities in a variety of different contexts.”
Illustration by Liz Zonarich/Harvard Staff
Arts & Culture
Better than the book?
Faculty recommend their favorite reads adapted for the silver screen … and maybe even improved in the process
Sy Boles
Harvard Staff Writer
February 26, 2025
7 min read
“The book was better.” In any conversation about a film adaptation, someone is bound to say it. But some books were just meant to be adapt
Faculty recommend their favorite reads adapted for the silver screen … and maybe even improved in the process
Sy Boles
Harvard Staff Writer
7 min read
“The book was better.” In any conversation about a film adaptation, someone is bound to say it. But some books were just meant to be adapted, and some adaptations say new and interesting things about the source material. Just in time for Oscar season — which features several Best Picture nominees based on books, including “Conclave,” “Nickel Boys,” and “A Complete Unknown” — we asked Harvard faculty and staff to share their favorites.
Angela Allan
Associate Director of Studies and lecturer in American literature, economic history and popular culture
‘Misery’
Stephen King
Allan recommended two classics that are well-loved on both the page and the screen.
“I love Stephen King’s 1987 horror novel ‘Misery,’ which has a pretty straightforward plot: Best-selling romance novelist Paul Sheldon is held captive by his ‘No. 1 fan’ Annie Wilkes, who wants him to write a novel just for her. Oh, and Annie happens to be a murderer! But what I also admire about the novel is that it’s such a great meditation on what it means to be a writer. I’ve read it a few times and taught it here at Harvard, and while it’s a very fun read — but definitely not for the squeamish — there’s a lot more to it. Stephen King wrote it after he had a streak of best-sellers in the 1980s (and the streak is still going), so this drama between Paul and Annie is really an examination of fame, success, and the impact on literature. The 1990 film with James Caan and Kathy Bates, who won an Oscar for Best Actress, is a faithful adaptation, but you lose some of the insight about writing and reading in the translation from page to screen.”
‘L.A. Confidential’
James Ellroy
“My other pick is a novel that’s partially about the film industry. As a lover of film noir, I really enjoyed James Ellroy’s 1990 novel ‘L.A. Confidential,’ which is a gritty homage about the moral rot of 1950s Los Angeles hidden behind Hollywood glamor. I’ll be honest, as crime fiction goes, there are a lot of ugly and shocking things in the novel’s elaborate — and at times, overwhelming — plot. And there are certainly no real heroes, since it focuses on the corruption within the police department, but it’s a masterpiece of character development. The 1997 film, which was nominated for Best Picture (I think it should have beaten ‘Titanic’), is one of the best adaptations of a novel I’ve ever seen. It significantly edits the plot to make it more film-friendly, but it absolutely nails the characters and feel of Ellroy’s Los Angeles. For something that’s so much about the illusions of Hollywood, the adaptation makes the story its own while also capturing its essence.”
Derek Miller
Professor of English, Director of Graduate Studies
‘Jack Reacher’ series
Lee Child
Miller has been working his way through the mystery/thriller “Jack Reacher”series, starring an ex-military police officer who wanders the U.S. “with just the clothes on his back and a toothbrush in his pocket.”
“The mysteries themselves are often of merely marginal interest,” Miller said. “I have appreciated instead the slow changes in Child’s technique and thematic interest from book to book. In one volume, Reacher’s obsession with coffee inspires a paragraph-long encomium to a diner’s cup of joe. Another book meditates on the psychology of a driver who would stop for a hitchhiker as imposing as Reacher. A third discourses on the evolutionary biological advantages that make our hero such a fierce warrior. It’s pop fiction, full of stock phrases and situations — every time Reacher gets into a car, he ‘racks the seat back’ to make room for his large frame — but usually executed with skill and verve.
“Little wonder that the series has inspired two films starring Tom Cruise (controversially, given Cruise’s small physical stature) and now a third season of streaming television on Amazon Prime. On the big or small screen, the essentially melodramatic structure of Child’s stories — a Manichean worldview, stock characters and situations — stands out more starkly than in the comparatively digressive novels and short stories. Yet whether on screen or on the page, the series and the character represent well some of the pleasures of popular entertainment: vividly drawn heroes and villains; swift, suspenseful plotting; and a writer continually experimenting with the possibilities within his successful formula.”
Version 1.0.0
Martin Puchner
Byron and Anita Wien Chair in Drama and of English and Comparative Literature
‘The Hoods’
Harry Grey
Puchner says there’s nothing particularly special about the 1952 semi-autobiographical novel that Grey wrote when he was in prison and gives an account of a Jewish gang from New York’s Lower East Side during Prohibition. It’s the adaptation that really shines.
“What is striking is how two Italians, the director Sergio Leone and composer Ennio Morricone, transformed this work into a masterpiece, the 1984 film ‘Once Upon a Time in America.’ They understood that film is essentially an operatic genre, that it’s driven by the interplay of scenic images and music on a grand scale, and that dialogue and acting are secondary. Years earlier, they had pioneered this operatic approach to film with the Western, producing their early masterpiece, ‘Once Upon a Time in the West’ (1968), in which images and music have equal weight. The dialogue of that movie runs to about 15 pages, a small fraction of a regular screenplay.”
David Levine
Professor of the Practice of Performance, Theater, and Media
‘American Psycho’
Bret Easton Ellis
Levine said he generally finds movie adaptations to lack something in translation. “The Hollywood idea that if it works as a book, it’ll definitely work as a film just seems so deeply misguided. The book-to-film adaptations I’ve really enjoyed are the ones that either bring life to meh novels, or adaptations that are so off-kilter they place the novel in a new light. A good example of the latter is Mary Harron’s adaptation of Bret Easton Ellis’ ‘American Psycho,’ which takes Ellis’ relentlessly anhedonic novel and braids its strands of humor into something extraordinarily lively and rich. (Predictably, Ellis hated it).”
Brittany Gravely
Publicist & Designer, Harvard Film Archive
‘Where Are You Going, Where Have You Been?’
Joyce Carol Oates
Gravely recommended a short story rather than a book, calling Oates’ 1966 piece “exquisite.”
“Spending only a few pages painting the angsty suburban life of a teenaged Connie, the bulk of the short story is dedicated to a spellbinding showdown between the girl and a stranger whose unnerving menace gradually metastasizes into a grim nightmare,” she said.
Filmmaker Joyce Chopra adapted the work into the 1985 movie “Smooth Talk.”
“Chopra develops the buildup, fleshing out Connie — played by Laura Dern, who even Oates said was ‘dazzlingly right’ — and her emotional experience. Dern depicts Connie’s bursting out of suburban girlhood like a lanky, beautiful fledgling — excited, contradictory, narcissistic, afraid. The film also deepens the roles of each family member and their individual dynamics. Even the perpetually half-renovated home in the middle of nowhere — mentioned maybe in a sentence or two — becomes a central, crucial presence. More dramatically, Chopra changed and complicated Oates’ presumably fatal ending to an offscreen, unnamed horror that Connie survives.
“While maintaining the quirkiness, the terror, and the stark symbolism within Oates’ story, Chopra crafts it into a work of immersive naturalism, letting audiences get to know Connie and unconsciously root for her before the scary turn of events. In the film’s form, the original ending would have taken over the film and become its focus; whereas by letting Connie’s story continue — in a heartbreaking final scene of adolescence lost — all those twisting emotions, reactions, and relationships linger and drift toward any number of futures the viewers are left to envision. There is no exact duplicate when adapting literature to film, but there is taking perfect prose and allowing it to grow within an appropriate cinematic container, as Chopra did so tenderly with Oates’ tale.”
Ding Liu (right), a postdoctoral researcher in the lab of Catherine Dulac (left).Veasey Conway/Harvard Staff Photographer
Health
Food, water — and a friendly face
Health professionals view social contact as basic human need. Now researchers have tracked neurological basis for it.
Clea Simon
Harvard Correspondent
February 26, 2025
5 min read
Health and medical professionals have come to vi
Health professionals view social contact as basic human need. Now researchers have tracked neurological basis for it.
Clea Simon
Harvard Correspondent
5 min read
Health and medical professionals have come to view social connection as a fundamental human need akin to food and shelter. In fact the U.S. Surgeon General highlighted social isolation as a major public health concern in 2023.
However, the mechanics of how loneliness or instinctive social need is encoded in the brain are unclear. A new study published in Nature, “A Hypothalamic Circuit Underlying the Dynamic Control of Social Homeostasis,” explores the neurological basis for this need, uncovering the systems that govern the desire for company.
“Recent studies, including ours, suggest that social needs are similarly important for the health of animals as other [basic] needs,” said Ding Liu, a postdoctoral researcher in the Catherine Dulac Lab and Nao Uchida Lab in the Department of Molecular and Cellular Biology and the Center for Brain Science, who led the study.
Moreover, the inability to engage in fruitful social interactions is one of the most debilitating aspects of mental illnesses such as autism, depression, and schizophrenia, said Dulac, the Samuel W. Morris University Professor.
She noted that while researchers do not understand why this is so, gaining a mechanistic understanding of how the brain regulates the urge to be with other people will provide critical information on healthy and diseased brain states associated with social context.
What if the desire for social interaction was not driven by wanting to feel good but avoiding feeling bad — as is the case with hunger and thirst?
To understand the need for social interaction, Liu and his team turned the conventional approach on its head. “A generation of research has been talking about the rewarding nature of social behavior,” said Liu, citing such compounds as dopamine, oxytocin, and serotonin, which are released by social interaction and produce feelings that reward this interaction.
Instead they asked: What if the desire for social interaction was not driven by wanting to feel good but avoiding feeling bad — as is the case with hunger and thirst? Researchers have identified neurons that trigger such drives associated with aversive experience.
“For example, if we are looking for the ‘hunger neurons,’ we should look for the neurons that are active during the time we are deprived of food, rather than the feeding period,” explained Liu.
Hypothesizing that the need for social behavior may be more like those for hunger or thirst, the team focused on neural activity in the hypothalamus, the site of neurons governing these other needs.
Aiming to identify the neurons triggered by isolation, the researchers created a scenario. By isolating mice for several days, they identified two distinct periods: the deprivation phase (when the mice were alone) and the reunion phase (when the animals were once again together).
They then observed, using activity-based gene expression and in vivo calcium imaging, which neurons become active during periods of “social seeking” (that is, the deprivation phase), and “social satiety” (the reunion phase).
Complicating their findings was the discovery that if mice are deprived for too long, their response changes. “If you isolate the mice for more than four weeks, they start to dislike social behavior,” he said. Isolation has become the norm, and having company is disruptive, he hypothesized.
The researchers also looked at how sensory inputs contribute to social need in mice. In one experiment, mice were physically separated from siblings but could see, hear, and smell them through a perforated divider. But the end result was similar to that of the social isolation experiment, suggesting touch stimulation is indispensable for the fulfillment of social need.
To explore this further, the researchers created a touch preference experiment, in which mice could choose to enter a tunnel lined with soft cloth or one of bare plastic. The mice had a clear preference for the cloth tunnel after social isolation.
“At least for mice,” concluded Liu, “touch is a super important modality to sense the change of social environment.”
This, he noted, may have direct relevance for humans. “For humans, touch is a very important part of social behavior as well,” he said. “We hug each other; we shake hands; and in intimate relationships we even have more touch-based behavior.”
These days, when more and more of our interactions are on screens rather than in person, such research may unlock clues to how we humans react. For people “overwhelmed by the internet,” hypothesized Liu, “touch is one thing that is missing.”
“Studying why we need to socialize helps us understand the biological and psychological foundations of human behavior,” said Mostafizur Rahman, a postdoc in the Dulac Lab and one of the paper’s authors. “By exploring these roots, we can better understand how social bonds influence our mental health, and relationships with others.”
Concluded Dulac: “Our discovery of similar neural circuit architectures to encode social need and physiological needs such as the needs for water, food, and sleep directly illustrates how fundamental social interactions are for healthy lives.”
This work was supported in part by funding from the National Institutes of Health.
Arts & Culture
Art from all corners
The Harvard University Band performing for the Office for the Arts 50th birthday celebration at Sanders Theatre.Photos by Niles Singer/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
February 26, 2025
5 min read
Office for the Arts celebrates 50 years with storytelling, music, dance, poetry, and more
As a first-year, Tiffany Onyeiwu
The Harvard University Band performing for the Office for the Arts 50th birthday celebration at Sanders Theatre.
Photos by Niles Singer/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
5 min read
Office for the Arts celebrates 50 years with storytelling, music, dance, poetry, and more
As a first-year, Tiffany Onyeiwu ’25 was excited to learn about the ceramics studio in the Quincy House basement. Onyeiwu had loved art in high school, but sacrificed taking classes in favor of rigorous courses that she felt would strengthen her college applications. The idea of creating again was irresistible.
“As I nestled my hand onto a neatly kneaded lump of clay on the potter’s wheel, chaos ensued,” Onyeiwu told an audience at Sanders Theatre. “Slip started moving everywhere, splattering across my limbs. But finally I found my center and got everything under control. I danced with the clay in that moment, directing it but also listening to its energy, spinning and turning and moving in a continuous rotation.”
President Alan Garber shared how his early interest in photography expanded his world.
With support from the OFA, Maranatha Paul ’26 produced a short film.
Professor of the Practice of Theatre Diane Paulus ’88 and Karina Cowperthwaite ’19 discussed their parallel career trajectories that brought them to the American Repertory Theater.
Actor Courtney Vance ’82 and his daughter, Bronwyn Vance ’28, told their stories.
Kate Vandermel ’25 performed an operatic rendition of the Harvard College mission statement.
African dance troupe Omo Naija X Wahala Boys brought action to the stage.
Many students had similar experiences to share at the OFA’s 50th birthday celebration this month, an evening filled with storytelling and performances in music, dance, poetry, and more. Students, administrators, and alumni took turns reflecting on their involvement with the arts on campus.
“The OFA is an idea and a promise,” said Office for the Arts Director Fiona Coffey. “The OFA is a declaration that the arts are not ancillary, but vital to a Harvard education. The OFA is confirmation that knowledge and pedagogy are produced in traditional academic classrooms and also in art studios, in music rehearsal rooms, and on stages.”
Maranatha Paul ’26 said he was awestruck the first time he read Shakespeare’s “Othello” in high school — a moment that inspired him to pursue writing seriously. Paul is now an English and Theater, Dance & Media joint concentrator, and has worked on student-written theater productions and produced a short film with support from OFA funding.
OFA Director Fiona Coffey invited audience members who saw themselves as “champions of the arts” to switch on flashlights they had received when entering the theater.
“When you read a short story or a poem or you go to see a film or watch a play, what you’re effectively witnessing is someone’s perspective of the world,” Paul said. “Not a single human being has ever seen your perspective on anything. There’s no telling who you might inspire, who might be seen by you. So just write it, get out there, and see what happens.”
President Alan Garber spoke about how his childhood interest in photography expanded to a love for films after he got a job working at a movie theater in high school while saving up to buy a camera.
“I think that’s something that art does for all of us,” Garber said. “The aperture, once open, tends to widen, tends to let in more work done in more ways, to include more artists. Each encounter causes us to see and appreciate the world in a different way, and to see and appreciate people in different ways.”
Professor of the Practice of Theatre Diane Paulus ’88 and Karina Cowperthwaite ’19 discussed their parallel career trajectories from on campus theater involvement to the American Repertory Theater. Actor Courtney B. Vance ’82 spoke about getting his start in theater at Harvard, while his daughter BronwynVance ’28 spoke about first hating, then loving, the piano.
The event also featured performances by Harvard Bhangra, African dance troupe Omo Naija X Wahala Boys, 2023 National Youth Poet Laureate Salome Agbaroji ’27, Mariachi Véritas, and others. Former OFA directors Jack Megan and Myra Mayman were recognized for their leadership, and Kate Vandermel ’25 and Henry Wu ’25 performed an operatic rendition of the Harvard College mission statement on voice and piano.
At the end of the show, Coffey invited audience members who saw themselves as “champions of the arts” to switch on tiny flashlights they had received on entry. In an instant, Sanders Theatre transformed into a shimmering galaxy of twinkling lights.
“Artmaking is born from courage, the courage to be vulnerable, to expose your soul, to see others and to be seen, to step into somebody else’s shoes, her voice or perspective, with compassion, openness, and humility,” Coffey told the students. “Be brave, work hard, dream harder, and let your light shine. We need more of your light in this world.”
Arts & Culture
‘A voice that must be heard’
Gabriela Ortiz.Courtesy of DRCLAS
Nikki Rojas
Harvard Staff Writer
February 25, 2025
5 min read
Grammy winner, Mexican classical composer Gabriela Ortiz on taking inspiration from folk music, ‘Glitter Revolution’ protests
She is a classical composer who is heavily influenced by the folk music and instruments of her native Mexico. Along the
Grammy winner, Mexican classical composer Gabriela Ortiz on taking inspiration from folk music, ‘Glitter Revolution’ protests
She is a classical composer who is heavily influenced by the folk music and instruments of her native Mexico. Along the way, some teachers and others judged her works to be too exotic.
But at the Grammys this month, Gabriela Ortiz’s “Revolución Diamantina,” inspired by Mexico’s 2019 eponymous “Glitter Revolution” feminist protest targeting gender violence, took home three awards, including one for performance for conductor Gustavo Dudamel and the Los Angeles Philharmonic, and one for Ortiz herself for composition.
Ortiz, 60, will join Alejandro L. Madrid, the Walter W. Naumburg Professor of Music, on Wednesday for a conversation on campus about her long career and her latest projects. Ortiz, who just finished a season as Carnegie Hall’s composer in residence, has long dedicated her work to infusing the sounds of Mexico into classical music.
“My childhood was around music all the time, and my parents founded this incredible group called Los Folkloristas, dedicated and devoted to promoting the music of Mexico,” she said. Band rehearsals with folk instruments from across Latin America served as the soundtrack of her home. “I felt very grateful and lucky to be able to listen to this incredible music and to learn how to play it,” she added.
Well-known in Mexico and throughout Latin America and Europe, Ortiz has been active in the U.S., drawing various orchestra commissions in Los Angeles and New York, according to Madrid.
“Arguably she is the most successful Latin American composer of today,” he said. “She’s the one that’s probably receiving some of the most important commissions of orchestras in the United States and in Europe.”
“Revolución Diamantina” was Ortiz’s first full album of orchestral works. She composed the ballet, also her first, in collaboration with her brother Rubén Ortiz-Torres, professor of visual arts at UC San Diego, and Pulitzer Prize-winning Mexican author Cristina Rivera Garza, the M.D. Anderson Professor in Hispanic Studies at the University of Houston.
“I always wanted to write a ballet. In another life I would have been a flamenco dancer because I love flamenco. I love dance in general. It’s my second passion,” Ortiz said. When she received the commission from the LA Philharmonic, she knew it was her chance to write a ballet about a significant topic.
Her brother’s artwork involving glitter paint led her to think about Mexico’s recent protest movement for women’s rights and legal protections.
“What brought them together was their interest in the feminist wave in Latin America and how it’s manifested in Mexico with this moment that was called the ‘Glitter Revolution,’ where women took to the streets demanding equality of rights and an end to violence against women,” Madrid explained.
The feminist movement began as a series of protests in 2019 after a 17-year-old girl reported she had been raped by four police officers. Demonstrators smashed bus stops, shattered windows of police stations, and painted graffiti on historic monuments. The crowds of mostly women demanded an end to gender violence in a nation where 10 women are killed a day on average and in a region where 98 percent of gender-related murders go unprosecuted.
The revolution earned its name from the fact that protesters showered police officers with glitter.
“I understand that kind of violence because I wouldn’t want to be in the place of the mother that has to deal with a dead daughter,” Ortiz said.
Although working in LA at the time of the marches, Ortiz solicited recordings from protesters and received thousands of responses. “At some point, I wanted to produce something with those recordings,” she said. The recordings would later inform her award-winning ballet, which included a dramaturgy written by Garza.
“Revolución Diamantina” is far from Ortiz’s first project focused on contemporary issues, Madrid said. The composer’s “Únicamente la verdad” (“Only the Truth”) revolves around the mythical origin story of Camelia la Texana, a character in the band Los Tigres del Norte’s narcocorrido “Contrabando Y Traición” (“Smuggling and Betrayal”). Ortiz has also written a choral composition called “Yanga,” about a 16th-century African prince who escaped enslavement and founded a free town in Mexico.
“She’s always writing about things that are very important in terms of our current world, but also in terms of politics,” Madrid said. The music professor is eager to introduce Ortiz to the Harvard community and discuss an upcoming showcase of “Revolución Diamantina” in Boston.
The campus event is being sponsored by the David Rockefeller Center for Latin American Studies, the Department of Music, the Department of Romance Languages & Literatures, and the Consulado General de México en Boston.
Madrid hopes students “get a sense that this tradition also belongs to them and there’s a woman who’s composing, is part of this tradition, and is in conversation with all of these artists from all over the world.”
Ortiz has broken many glass ceilings in Mexico, Madrid said; she “has a voice that must be heard.”
Health
Older adults at highest risk for suicide, yet have fewest resources
Study highlights imbalance in targets of online suicide prevention efforts
Katrina Fu
Mass General Brigham Communications
February 25, 2025
3 min read
Older adults, particularly those aged 75 and older, have the highest rates of suicide of any age group, yet a new study finds that well-known national suicide preve
Older adults at highest risk for suicide, yet have fewest resources
Study highlights imbalance in targets of online suicide prevention efforts
Katrina Fu
Mass General Brigham Communications
3 min read
Older adults, particularly those aged 75 and older, have the highest rates of suicide of any age group, yet a new study finds that well-known national suicide prevention organizations do not provide easily accessible resources targeting this population.
The study was led by researchers at Harvard-affiliated McLean Hospital. Their findings, published this month in The American Journal of Geriatric Psychiatry, highlight the urgent need for suicide prevention efforts that address the unique healthcare needs of older adults.
“As clinicians and researchers in geriatric psychiatry, we frequently work with older adults who express suicidal thoughts,” said senior author Ipsit Vahia, chief of the Division of Geriatric Psychiatry at McLean, a member of the Mass General Brigham healthcare system. “Our team was interested in understanding how an older adult in the community may seek resources around suicide prevention and what they are likely to find. What we uncovered was an imbalance in who online suicide prevention efforts are targeted toward, and a great unmet need for older adults.”
The work, carried out in the Technology and Aging Laboratory at McLean, was driven by the fact that older adults are increasingly using internet resources to seek health information. Investigators focused their online search on well-recognized, nonprofit organizations or federal agencies that appear on the first page of a Google search, intending to replicate the natural search process of older adults using the internet.
Their findings revealed that resources targeting older adults were scarce and not easy to find, even though most of the websites they came across acknowledged the high risk of suicide among this population.
Adults aged 75 and older have one of the highest suicide rates (20.3 per 100,000) according to the Centers for Disease Control and Prevention. CDC estimates have revealed declines in suicide rates in several age groups under 34 years old in recent years, whereas the rate in adults over 75 has increased.
This may be due to social isolation and loneliness, underrepresentation in research, and systemic implicit biases against older adults, according to Vahia.
“Public-facing suicide prevention campaigns have a record of effectiveness, and the need for such campaigns targeting older adults is greater than ever,” he said. “Our hope is that shedding a light on this imbalance may lead to major suicide prevention organizations considering ways to make their resources more easily accessible to older adults.”
Regarding next steps, the team emphasized that addressing the disparities in suicide prevention efforts for older adults will require targeted campaigns and tailored prevention programming that factor in their unique healthcare needs, and can be featured on easily accessible, online platforms. They add that increased funding and research focused on late-life suicide prevention is needed.
Vahia receives current research support from the National Institute on Aging, the National Institute of Mental Health, the Once Upon a Time Foundation, and the Harvard Dean’s Initiative on Aging. The study was funded by an unrestricted gift from the Eric Warren Goldman Charitable Trust and the McLean Technology and Aging Lab.
Photo illustration by Judy Blomquist/Harvard Staff; photos by Dylan Goodman
Campus & Community
The team behind the team
Dylan Goodman
Harvard Correspondent
February 25, 2025
4 min read
From analyzing statistics to setting out chairs, student managers help carry the sports they love
Behind every great team are student managers. To the coaches and players, they are indispensable, arriv
From analyzing statistics to setting out chairs, student managers help carry the sports they love
Behind every great team are student managers. To the coaches and players, they are indispensable, arriving well before the first whistle and staying long after the final play. Their duties are broad and are constantly evolving, from analyzing statistics to filling up water bottles. They embody the same commitment and passion as the athletes they support. They are the team behind the team.
To the managers themselves the role is more than a job — it’s a way to stay connected to a sport they love (and sometimes played themselves), contribute to something bigger than themselves, build relationships, and for some lay the foundation for a career in sports.
Debora Ortega-Maldonado ’26
Football Team
Debora Ortega-Maldonado.
Ortega-Maldonado, who took her high school manager’s job to Harvard football, is proud of the two Ivy Championships the team has earned during her watch.
“The most rewarding part of my job is getting to see how all the practice the team does and all their hard work is transferred over to game day,” she says.
Ortega-Maldonado is at every practice and game. Unlike the players, who follow strict schedules, managers set their hours themselves, balancing their responsibilities with an equally, if not more, time-consuming commitment.
Michael Poirier, J.D. ’25
Men’s Basketball Team
Michael Poirier.
“I’ve wanted to work in the NBA since I was a kid, so this has only reinforced that dream,” says Poirier.
A former player at Lakehead University, Poirier now plays a pivotal role in the inner workings of the men’s basketball team while balancing his studies as a 3L at Harvard Law School. His managerial work ranges from watching game films and tracking statistics to assisting with recruiting materials. Even small matters like setting up chairs during timeouts fall to him.
“It’s one of my favorite parts of my Harvard experience,” he says of his role as a student manager.
Tommy Amaker, the Thomas G. Stemberg ’71 Family Endowed Head Coach, emphasizes the vital role students like Poirier play in the program: “Our student managers are as important as anyone in our basketball program. They work incredibly hard and show an unwavering commitment. Our success is directly tied to our managers.”
Claire Pak ’26
Women’s Lacrosse Team
Claire Pak.
For Pak, the best part of working with the women’s lacrosse team is the relationships she has built with players and coaches. She has “gotten incredibly close to many girls on the team,” says the Quincy House resident.
Pak supports the team “in every way,” managing equipment, filming practices, inputting and analyzing key statistics, and making sure the snack bin is always full. The work requires sacrifice. She spends from eight to 12 hours each week with the team and sacrifices her weekends to travel to games.
“It’s all worth it,” she says.
Devon Wills, the Carole Kleinfelder Head Coach for Harvard Women’s Lacrosse, says, “Our student managers, especially Claire, … are the backbone of our team, ensuring that all the little details are taken care of at practice and on game days so we can focus on performing.”
Andrea Tchinda ’27
Women’s Basketball Team
Andrea Tchinda.
Tchinda had played her sport in high school and arrived at Harvard knowing she wanted to work with the women’s basketball team. The summer before her first year, she emailed Carrie Moore, the Kathy Delaney-Smith Head Coach for Harvard Women’s Basketball, to be sure she would be able to start as a manager on her first day. She stresses the importance of believing in the team’s mission and working toward maximizing their goals.
“A lot of times this means putting the team before yourself, even though you are not a player or a coach,” she says.
Moore recognizes this commitment, explaining that Tchinda “has a love for the game of basketball, but also a genuine love for our players and staff.”
Andrew Arkow ’27
Men’s Tennis Team
Andrew Arkow.
As the men’s tennis student manager, Arkow finds himself handling everything from video analytics and logistical support to operating the scoreboard and picking up freshly strung rackets.
Arkow is also a member of the team, but his connection to Harvard tennis runs even deeper — his brother, David, played for the Crimson from 2020 to 2024.
“Tennis has always been a big part of my life,” he says. The extra work as student manager is worth it — to help make the coaches’ and players’ “lives a little less stressful.”
Kinvard Bio co-founder Ben Tresco inspects a colony of drug-resistant bacteria.
Health
Harvard startup creating a new class of antibiotics
Compounds show promise against drug-resistant infections, diseases
Kirsten Mabry
Harvard Correspondent
February 25, 2025
7 min read
When penicillin, the first antibiotic approved for widespread use, became available in the 1940s, The New York Times rep
Harvard startup creating a new class of antibiotics
Compounds show promise against drug-resistant infections, diseases
Kirsten Mabry
Harvard Correspondent
7 min read
When penicillin, the first antibiotic approved for widespread use, became available in the 1940s, The New York Times reported it as “the most powerful germ killer ever discovered.” In 1945, many of the scientists involved in developing it were awarded a Nobel Prize for its significant impact on medicine. Humans had entered the antibiotic age, in which they could survive any number of infections and illnesses that had once been fatal.
But today, the picture has become much more complicated.
Antibiotics work by binding to or harming different parts of a germ’s structure. Penicillin, for example, binds to a part of the bacterial cell wall and degrades it. But germs are smart, and over time they can develop resistance mechanisms — like changing the target of an antibiotic so it can no longer bind properly or pumping the antibiotic out of the germ’s cell walls. These resistance mechanisms get passed on to other germs, meaning antibiotics once effective against an infection may not be any longer.
That has created one of the most serious health crises of our time. Antibiotic resistance, according to the World Health Organization, was responsible for more than a million deaths worldwide in 2019 and contributed to nearly 5 million deaths. Meanwhile, new classes of antibiotics are being approved at very low rates. Between 2017 and 2022, just a dozen antibiotics were approved worldwide and only two of those were from new classes that work in a different way than existing medicines.
Enter Kinvard Bio, a biotechnology company that on Monday announced its launch out of the Myers Lab in the Department of Chemistry and Chemical Biology at Harvard University. The startup is creating a new class of antibiotics in the hopes of treating drug-resistant infections and diseases.
Andrew Myers, the Amory Houghton Professor of Chemistry and Chemical Biology at Harvard, had already established himself as one of the world’s pre-eminent synthetic chemists when he decided to focus much of his lab’s efforts on addressing the global health crisis caused by antimicrobial resistance. Chemists have long come to Harvard to learn from Myers. And for over a decade, those scientists have contributed to innovations that can impact this significant unmet health need.
The lab’s research is not only creating new compounds that could alleviate an intractable problem but also cultivating the next generation of scientists who can continue confronting the challenge. Kelvin Wu, a Kinvard Bio co-founder who co-led the research team as a graduate student in the Myers Lab, hopes the company’s platform will help solve the “resistance crisis,” he says. “Antibiotic discovery is a global problem that I personally am very worried about.”
Kinvard Bio CEO Lloyd Payne echoed Wu’s concerns about treatment options becoming more limited. “There is a critical need for continued innovation to deliver new antibacterials into the pipeline to ensure that we are able to successfully treat challenging drug-resistant infections for generations to come.”
The new medicines that Kinvard Bio are developing focus on the bacterial ribosome, an antibiotic target that is highly clinically validated, according to Payne. Though there are already a number of antibiotics that target the ribosome, Kinvard Bio’s antibiotics — called the oxepanoprolinamides — are structurally preorganized for highly effective binding to the target.
“The bacterial ribosome is an incredibly important target as it is clinically validated and essential across a broad range of clinically relevant pathogens, but the important thing — and this really is key — is the fact that the oxepanoprolinamides bind to the ribosome in a highly differentiated way,” Payne said. “There is further work to do to progress the program into human clinical trials, but this binding mode affords promising potential for the avoidance of pre-existing resistance to currently used antibiotics.”
The Myers Lab has been working on developing this class of compounds for more than a decade. But they have even deeper roots — dating back to the 1960s, not too long after penicillin ushered the world into the antibiotic age. In 1964, the Federal Drug Administration approved lincomycin — an antibiotic isolated from a soil microbe — a significant breakthrough, says Payne, because, at that time, it was an alternative for people allergic to penicillin.
“This was an underexploited class of antibiotics that was ripe for revitalization,” said Wu.
Myers’ team received funding and other support from Harvard’s Blavatnik Biomedical Accelerator to help further their work, including the synthesis and testing of new compounds, leading to a 2021 paper in Nature.
For some elements of the design, the team had to invent entirely new chemistry. “One of the reasons that this program has been successful is our ability to put the molecules together very efficiently. Using chemical synthesis, we can start with simple building blocks and then stitch them together into a really complex molecule,” said Ben Tresco, Kinvard Bio co-founder, who led the research team along with Wu as a graduate student in the Myers Lab. “The reason these molecules are so different from their predecessors — the other molecules that bind in this site — is that they are so well optimized for binding to the bacterial ribosome.”
In 2024, the team received a $1.2 million grant from the Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) and additional support from the Blavatnik Biomedical Accelerator to further develop the antibiotics. Kineticos Life Sciences, an investment firm focused on companies in oncology, rare diseases, and antimicrobial resistance, through its relationship with CARB-X, was introduced to the technology via Harvard’s Office of Technology Development (OTD). Kineticos incubated and funded the company through the Kineticos AMR Accelerator Fund I.
“OTD was instrumental in making sure that investors were aware of what the research team was working on and that there was great potential for a new company to be formed,” said Curtis Keith, the chief scientific officer at the Blavatnik Biomedical Accelerator.
Early preclinical studies have shown the antibiotics are active against a broad range of pathogens implicated in a range of infections, including those resistant to other antibiotics.
The startup is initially building a pipeline focused on acute and chronic infections associated with high unmet patient need, such as bacterial pneumonia, complicated urinary tract infections, and chronic respiratory infections, with the aim of developing both intravenous and oral formulations. Both routes of drug delivery are important because oral antibiotics can be effective in reducing hospital admissions and lengths of hospitalization. Spending more time in a hospital increases the risk of acquiring new infections. Eventually, applications could expand to include notoriously challenging chronic infections such as nontuberculous mycobacteria lung disease.
According to Keith, the science is in line with what the Myers Lab is all about — applying synthetic chemistry to tackle some of the world’s most pressing challenges. “They’re not just conducting chemistry that will remain in the lab; the research team is focused on developing practical solutions that could lead to effective and accessible antibiotics.”
Research reported in this article is funded by the National Institutes of Health and by CARB-X, whose funding for this project is provided in part with federal funds from the U.S. Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority; Wellcome; Germany’s Federal Ministry of Education and Research; and the UK Department of Health and Social Care as part of the Global Antimicrobial Resistance Innovation Fund.
Niles Singer/Harvard Staff Photographer
Campus & Community
Stepping into the hot center
Liz Mineo
Harvard Staff Writer
February 25, 2025
5 min read
Tarek Masoud’s ‘Middle East Dialogues’ sparked many conversations — including about importance of having them
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
A week after the Oct. 7, 202
Tarek Masoud’s ‘Middle East Dialogues’ sparked many conversations — including about importance of having them
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
A week after the Oct. 7, 2023, Hamas-led attacks on Israel, Middle East expert Tarek Masoud led a well-attended forum with policymakers and scholars on the causes of the war and what might happen next in the conflict-ridden region.
Masoud, faculty director of the Middle East Initiative at Harvard Kennedy School, thought he was doing his part to educate and promote civil discourse on a divisive topic. A few weeks later, however, an HKS student complained in a Boston Globe op-ed piece that Harvard needed to do more to teach her about the Israeli-Palestinian conflict. Masoud was hearing similar complaints around campus and was taken aback.
“My first thought was to be very angry because I had been working hard to provide learning opportunities for our community on this issue,” said Masoud, Ford Foundation Professor of Democracy and Governance. “But I later concluded that there was a deeper truth to what the student was saying, that in fact we hadn’t fully engaged in a real debate about this very thorny issue.”
In response Masoud launched the “Middle East Dialogues” series last spring to hold conversations between people from across the political spectrum of the Israel-Palestine conflict. Masoud wanted the events to explore the historical, political, religious, and cultural complexities of what was going on. But he also wanted to model how to have hard conversations about hard topics on campus.
“Every single one of these speakers was being brought here not to be, quote-unquote, platformed or praised, but to be interrogated.”
“What students are really hungry for is to hear the most important arguments on either side,” said Masoud. “And instead of putting the speakers on panels, I was going to sit with them one on one and really probe their arguments. I wanted to create a space for us to give full voice to the debate.”
And debate there was. The discussions drew accolades and criticism, with some of the harshest rebukes directed at Massoud for inviting Jared Kushner ’03, President Trump’s son-in-law and former Mideast adviser, and Dalal Saeb Iriqat, Arab American University Palestine professor of diplomacy and conflict resolution, as guest speakers. Some objected to Kushner’s lack of credentials, and others blasted Iriqat for her controversial comments on X, which described the Oct. 7 terror attack as a “normal struggle for freedom.”
In hindsight, Masoud said had he seen Iriqat’s posts beforehand he might not have invited her. The pushback against her visit included hate mail addressed to him and calls to cancel the event. But he ultimately decided to go ahead, noting her views represent those of a significant contingent of others around the world and so should be aired and closely examined.
“Every single one of these speakers was being brought here not to be, quote-unquote, platformed or praised, but to be interrogated,” said Masoud. “We have all kinds of visiting dignitaries and powerful people who come through Harvard, and oftentimes we just celebrate them and celebrate our proximity to them. That’s never what we should do. We should be civil and respectful and even friendly, but also relentless in holding their feet to the fire.”
The entire Dialogues project was a testament to Masoud’s belief in free inquiry and intellectual diversity, according to Derek Penslar, William Lee Frost Professor of Jewish History and director of the Center for Jewish Studies.
“Tarek’s speaker series on Israel/Palestine has done exactly what Harvard needs at this time — bringing together public figures and experts representing different views, fostering lively exchange and respectful disagreement, and not shying away from difficult issues,” Penslar wrote in an email. “Tarek’s intellect, energy, and kindness are inspiring.”
Students want to hear alternative points of view, and faculty and administrators should provide them with opportunities to hear a variety of perspectives, Masoud said.
“The majority of our students are earnest seekers of the truth,” said Masoud. “The fact of the matter is that it’s our responsibility to our students to not do the easy thing, which is to tamp down anything that’s disagreeable. There’s this old American dictum that says that you shouldn’t talk about politics or religion at the dinner table. Well, if you say we shouldn’t talk about politics or religion at Harvard, you might as well close Harvard.”
Masoud plans to continue with the Dialogues in the spring, but he’s broadening it to other hot topics such as the competition between various Arab countries and Iran, the power race between the U.S. and China, and U.S. foreign policy in the Middle East.
“In an intellectual environment like this, that’s full of very high-powered, highly intelligent people who are all trying to make a difference in the world, you’re going to have a lot of contested ideas, a lot of debate, a lot of argument,” said Masoud. “Talking about these things does not make us happy, but these hard conversations have the potential to increase human happiness if they get us closer to the truth and closer to solutions to these very hard problems.”
A Ukrainian soldier launches a drone from a shelter in partially occupied Toretsk, the site of heavy battles with the Russian troops in the Donetsk region.Iryna Rybakova/Ukraine’s 93rd Mechanized Brigade via AP
Nation & World
What are the prospects for Ukraine?
Christina Pazzanese
Harvard Staff Writer
February 24, 2025
8 min read
Former top Ukrainian diplomat says options appear narrow as U.
A Ukrainian soldier launches a drone from a shelter in partially occupied Toretsk, the site of heavy battles with the Russian troops in the Donetsk region.
Iryna Rybakova/Ukraine’s 93rd Mechanized Brigade via AP
Former top Ukrainian diplomat says options appear narrow as U.S. aggressively pushes for ceasefire deal with Russia
Three years after Russia invaded Ukraine, the U.S. is now aggressively pushing both countries to reach a ceasefire deal. But critics of the Trump administration as well as most European nations are asking: At what price to Ukraine?
The U.S. has proposed a deal in which Ukraine would divert $500 billion in rare-earth mineral profits to Washington in exchange for aid but without a security guarantee. Ukraine’s President Volodymyr Zelensky, falsely attacked by Trump as a “dictator,” has thus far refused to sign the accord.
On Monday, the Trump administration voted against a United Nations resolution condemning Russian aggression against Ukraine and calling for the withdrawal of Russian forces. U.S. diplomats introduced a resolution calling solely for an end to the conflict. Both measures passed.
In this edited conversation held before the U.N. vote, Dmytro Kuleba, Ukraine’s chief diplomat from 2020 to 2024 and now a senior fellow at the Belfer Center for Science and International Affairs at the Harvard Kennedy School, shares his views on the war and Ukraine’s future.
In December, you said you remained optimistic about Ukraine’s position. How do you feel today?
Less optimistic. I personally, and Ukraine as a whole, we underestimated the pressure that Trump and his administration will begin to exert on Ukraine given his desire to strike a quick deal. We believed, based on our experience with President Trump during his first tenure, that he would be more balanced toward both Ukraine and Russia in this under these circumstances.
French President Emmanuel Macron and Keir Starmer, the British prime minister, plan to bring a proposal to the White House this week that would install 30,000 European troops in Ukraine to provide security, with the U.S. providing only backup support, possibly in the form of air and missile defense. If it comes to fruition, would that be enough to deter Russia?
Look at the size of Ukraine. Disperse 30,000 troops across the map, and you will see that it’s peanuts. The front line in the Russia-Ukraine war is essentially 3,000 kilometers [about 1,860 miles] long. Thirty thousand troops will not suffice to cover that line and that means they cannot serve as peacekeepers in the traditional understanding of this concept because they will not be able to stand between Russian and Ukrainian armies to prevent them from fighting.
So, we should not consider this idea as a real means of guaranteeing disengagement of forces. It is not a security guarantee; it is not even a security assurance, nor a stabilization force. It is just reassuring presence on the ground. Is the presence of such troops a good idea in principle? It is. Is it a real means of stopping the war? No, it isn’t.
We have to be realistic. Ukraine’s army is 1 million strong. About 400,000 troops are actively engaged in combat on both sides. Thirty thousand troops, even supported by air cover, can change very little. The second thing is that Russia most likely will be vehemently against this idea because, in their eyes, it will be the legitimization of at least some NATO armies on the ground in Ukraine. So, it’s a good idea, but I just don’t see how it can help to end the war.
Dmytro Kuleba.
Photo by Jodi Hilton
Trump officials are pressing Ukraine to agree to turn over a share of profits from Ukraine’s rare-earth mineral deposits in exchange for aid as part of ceasefire negotiations. Zelensky has said he won’t sign such a deal. Does he have much choice at this juncture?
Ukraine’s room for maneuvering is extremely narrow, to say the least. The main problem here is purely diplomatic. Russia has many gestures it can make to please or to engage with Trump and to show their constructiveness which are unrelated to the war itself. They released a U.S. citizen, which is, of course, welcome. This allowed President Trump to project strength and to demonstrate that a new attitude toward Russia pays off.
Ukraine does not have that luxury. Everything Ukraine has to offer or can do is related to the war. This puts Russia and Ukraine in completely different positions vis-a-vis Trump and his administration. This is the problem that Zelensky is facing.
Two hundred something drones attacked Ukraine just a couple of days ago. Did we hear a word of condemnation coming from the United States? No, we didn’t. This is what Putin will continue to do. He will continue to do something for Trump that does not slow down the pace of his aggression against Ukraine, and Zelensky will continue to fight against the unfair agreement without having anything else to suggest to Trump as an alternative. This is kind of the deadlock that Ukraine is currently in.
Will or should Zelensky step down if it brings about an acceptable agreement, as he’s offered?
We should be very clear: Ceasefire is not the end of the war. To the credit of the Trump administration, they have a very reasonable goal to establish a ceasefire as potentially a precondition to ending the war. But they’re only focused on this.
The reality is that establishing ceasefire is possible, but very difficult. Making it hold would be close to impossible, and ending the war is not looming on the horizon. Two completely different strategic goals.
Trump wants a ceasefire as a manifestation of his strengths and ability to strike the most difficult, challenging deal. Putin may agree to that, but his strategic goal of defeating Ukraine will remain unchanged. How to prevent him from doing that is not where the thinking of U.S. and Western strategists is — they did not really go that far. If, by the way, the notion of the West is still relevant at all.
Territory, money, and membership for Ukraine in NATO are the main issues on the negotiating table. What’s the best outcome Ukraine can hope for if the U.S. won’t provide further support?
Although I’m not a part of the government anymore, I’m still Ukrainian, and I cannot dwell on what kind of concessions Ukraine could make because that would simply weaken Ukraine’s position.
If Ukraine could be assured that there is a chance that putting NATO and territory issues on hold without legally recognizing that they are off the table, and Putin would stick to that agreement, that could work.
The problem is that everything we know about Russia suggests that it’s not going to stick to its word, and it will use any kind of pause or break just to prepare for the new attempt to destroy Ukraine. The issue is there is zero trust in Putin. Trump and his people manifest their belief that Putin can be trusted, and an agreement is possible, but everything we know about him suggests the opposite.
Would it be wise for Ukraine to consider ceding portions of its territory to Russia in exchange for an end to hostilities?
Putin’s goal remains unchanged. He wants the whole of Ukraine. He will ask President Trump: Who can guarantee that four years later the U.S. position will not reverse? There is no such guarantee that President Trump can give him. He can be promised that Ukraine will not be in NATO, but if Ukraine continues to exist as an independent nation, in Putin’s view, Ukraine will still end up in NATO five, 10 years later.
This is what this whole war is about. In dealing with another nation, it is fundamentally important to understand what its end goal is. The problem is that Putin knows what his end goal is, and the West doesn’t.
There is nothing easier in diplomacy than drawing lines on someone else’s map, deciding someone else’s destiny. We’ve seen it so many times in human history and also applied to Ukraine. Unfortunately, drawing these lines with a country that wishes to destroy another country is not a solution because it’s not going to hold. This is the fundamental issue: What will make the deal hold, if it is achieved at all?
Campus & Community
Keeping cool when debate turns hot
Dean Hopi Hoekstra gives opening remarks.Photos by Grace DuVal
Christy DeSmith
Harvard Staff Writer
February 24, 2025
5 min read
Inaugural global Ethics Center conference features scholarship, presentations on fostering civil, productive dialogue
Americans today are wrestling with how to turn down the heat when discussing politica
Inaugural global Ethics Center conference features scholarship, presentations on fostering civil, productive dialogue
Americans today are wrestling with how to turn down the heat when discussing politically and morally charged topics.
Students, professors, and education professionals from around the globe assembled at Harvard this month to chart their way to more productive discussions — and better relations. The inaugural Challenging Barriers to Civil Discourse conference, hosted by the Edmond and Lily Safra Center for Ethics, featured scholarship on fostering open, honest exchanges across deep divides.
It’s a pursuit central to a healthy democracy, said Hopi Hoekstra, Edgerley Family Dean of the Faculty of Arts and Sciences. “Civil discourse is one of my top priorities,” she told conference-goers. “Universities play a unique and critical role in modeling constructive dialogue, and I believe that our classrooms and campuses can — and should — serve as laboratories for meaningful engagement across differences.”
Several panelists provided practical tips drawn from Alternative Dispute Resolution (ADR), an umbrella term for methods used to resolve disputes without litigation. Julia Kolak, an instructor in the Department of Epidemiology and Population Health at the Albert Einstein College of Medicine and clinical ethics fellow at Montefiore Medical Center in the Bronx, offered a powerful account of the “values extraction” approach she uses when frictions arise between patients and clinicians.
Kolak told of mediating clashes that arose when women refused treatment for nonviable (and life-threatening) ectopic pregnancies, or when the family of a critically ill patient (suffering from cardiac arrest and septic shock) resisted end-of-life care. She works to unearth the principles guiding all parties, without elevating those with medical expertise. “When we treat others as capable of dialogue,” she offered, “it really changes the affective grip of conflict.”
Nicholas Buck onscreen at the conference.
Other conference speakers drew on historic wisdom. Nicholas Buck, a philosophy lecturer from American University, borrowed from Martin Luther King Jr.’s writings to illustrate why institutions should shift their focus from managing disagreement to building a sense of mutual belonging — what King called “the beloved community.”
One conference-goer asked how King’s ideas intersect with the worldwide rise of anti-intellectualism. “It seems to me it comes from a sense of exclusion,” Buck replied, circling back to King’s communal vision.
Philosopher Jeffrey Dunn invited attendees to join him for a little soul-searching. The associate director of the Prindle Institute for Ethics at DePauw University raised the critical question: “What is the long-term goal of this work?”
“It’s not really about changing views; it’s about building empathy or understanding for the other side,” he said. “Robert Talisse, the political philosopher, has a book where he argues that the way to increase empathy is not to discuss politics together, but to actually do nonpolitical things like play pickleball or join a softball team.”
The conference provided a taste of the sort of programming regularly offered by the FAS’ Civil Discourse initiative. It also marked a soft launch for the Ethics Center’s research and design studio, a hub for sharing civil discourse innovations.
“We hope this lab will advance basic research on civil disagreement, contribute to pedagogy, and advance social scientific measures of constructive dialog,” said Eric Beerbohm, the Alfred and Rebecca Lin Professor of Government and leader of the Ethics Center and the Civil Discourse initiative.
The fellows encountered a wealth of scholarship applying specifically to campus life. Marie Newhouse, an associate professor of law, philosophy, and public policy at the University of Surrey in the U.K., drew on Oxford philosopher Teresa Bejan’s “Mere Civility.” The 2019 title put philosophers Thomas Hobbes and John Locke in conversation with Rhode Island’s 18th-century founder Roger Williams.
“He established radically tolerant policies when it comes to religious and lifestyle differences in the community,” Newhouse explained. “He thought that keeping everybody talking to each other was the most important thing, and in order to achieve that he was prepared to deal with more rancor.”
Ideas from Bejan’s book were used to map a triangle of features inherent to any society wrestling with open inquiry: stability, discourse, and diversity. “It’s like that internet meme that gives you three things — fast, cheap, and good. Pick two!” Newhouse quipped.
She hypothesized that higher education had started to prioritize the Lockean ideal of social cohesion while suggesting it aim for something closer to Williams’ model.
“People enjoy living in cohesive communities,” Newhouse said. “But I wonder if it’s starting to interfere with the mission of the university, which requires robust discourse across deep disagreement.”
Equally relevant to current challenges besetting college campuses was a talk by St. Lawrence University education professor Jeff Frank about a recent project where faculty partnered with students to pilot a novel approach to advancing civil discourse.
An internal campaign they call “Be a Saint” trumpets the community’s shared values of listening, respect, and engagement with a bonus reference to the school’s athletics teams. The effort is currently being expanded to include initiatives tied to fortifying students’ mental health, Frank shared.
“It’s in everybody’s best interest to learn how to live in a pluralistic society,” he said. “So our messaging now is that this is in your personal best interest. You’re not just doing this for the institution.”
Illustration by Roy Scott/Ikon Images
Arts & Culture
Choice is a good thing, right?
Historian explores how having options became synonymous with freedom — and why it doesn’t always feel that way
Jacob Sweet
Harvard Staff Writer
February 24, 2025
4 min read
It often feels that we were put on earth to choose. Paper or plastic? Coke or Pepsi? “Have it your way,” Burger King beckons. In c
Historian explores how having options became synonymous with freedom — and why it doesn’t always feel that way
Jacob Sweet
Harvard Staff Writer
4 min read
It often feels that we were put on earth to choose. Paper or plastic? Coke or Pepsi? “Have it your way,” Burger King beckons. In controversial policy debates, Democrats and Republicans both use the language of choice to argue for their sides — pro-choice, school choice. Choice is a slam dunk, inseparable from contemporary notions of freedom.
It’s this sort of ubiquitous idea that most attracts Sophia Rosenfeld, Ph.D. ’96, professor of history at the University of Pennsylvania. After writing books on the history of common sense and truth, Rosenfeld tried choice. “It struck me as something particularly important that we rarely discussed,” she said. “Yet it was the unifying point, in many ways, for the way capitalistic culture and democratic culture intersect.”
In “The Age of Choice,” Rosenfeld traces choice’s meandering path to prominence and acceptance. She emphasizes that boundless choice wasn’t always accepted as the natural order of things — and wonders why, if it is supposed to be so freeing, it can often feel so burdensome.
The story of Adam and Eve, for instance, is not a testament to the powerful, freeing nature of choosing. Similarly, Rosenfeld points out that the allegory of Achilles’ choice between a long life or a heroic death is a scenario in which “decision making boiled down to two, unequal options.”
She references novels by Sylvia Plath, Margaret Wilkerson Sexton, and Frances Burney to trace the growing association between “choice-making and the construction of an autonomous, free self.”
In Rosenfeld’s view, consumerism ushered in centuries in which choice became increasingly important to social, economic, and political life. The first chapter delves into the origins of “shopping,” a once-novel experience invented by 18th-century British auctioneers.
The most prominent of the auctioneers, a Mr. Cock, pioneered a system of selling non-essential goods that turned the process of getting rid of inventory into a social event where people could peruse “choice” goods and flaunt their own powers of discernment. Instead of customers entering a market with a certain need, Mr. Cock encouraged them to view “shopping” as its own activity.
The practice spread, Rosenfeld writes: “[C]ustomers were repeatedly told by the mid-eighteenth century that they would confront situations in which plentiful ‘choices’ or ‘a great Choice’ or ‘the greatest of choice’ would be available, but also required of them.”
The centrality of choice moved from consumer life to social and political life, and often in ways that Rosenfeld acknowledges are positive.
Political movements for women’s suffrage, Civil Rights, and direct representation partially result from a public used to an expanded vision of personal choice. In various chapters, Rosenfeld traces how these changing norms influenced the freedom to choose religion, a partner, and elected officials in increasingly personal ways.
These explorations reveal unexpected origins for modern political and social practices.
Rosenfeld argues that the default way to vote in the U.S. — assembling in a public place only to vote in a private booth — results from an evolving view of personal choice. Whereas many American and English men once viewed voting individually and by personal whim as unbecoming, the growing primacy of individual choice helped lead voting away from public, often unanimous voting and toward the private ballot.
Throughout “The Age of Choice,” Rosenfeld challenges the idea that increasing the number of choices was always seen as the way to give people more freedom.
By narrating how the perception of choosing changed, she also reveals how, even in a broadly choice-happy society, there are still frameworks and historical precedents that shape the decisions we make. Though Americans take pride in the power to choose, few question laws against, say, choosing to give up a kidney for profit.
Similarly, Rosenfeld argues that more choice does not necessarily mean more freedom. Choosing one tube of toothpaste over several others might be a mild amusement, but having unregulated, ineffective toothpaste options would make that choice frustrating.
Sometimes, Rosenfeld believes, American emphasis on choice makes it hard to imagine political action that requires not a personal decision, but joint action. Instead of deciding between many healthcare plans with hard-to-predict contingencies, she said, “I think many of us would feel better off with one good plan.” Reaching that point would require more than just picking.
Rosenfeld is less concerned with the pitfalls of choice, though, and more interested in how it’s taken for granted. Choice has already won. But when we say we want choice, what do we really want?
Science & Tech
Hinting at answer to a chicken-or-egg question on evolution
Felix Elling, a former postdoctoral fellow at Harvard and lead author of the study.Courtesy of Felix Elling
Clea Simon
Harvard Correspondent
February 24, 2025
4 min read
Accidental find may help scientists resolve which evolved first: ability to produce oxygen by photosynthesis or consume it by aerobic metabolism
Hinting at answer to a chicken-or-egg question on evolution
Felix Elling, a former postdoctoral fellow at Harvard and lead author of the study.
Courtesy of Felix Elling
Clea Simon
Harvard Correspondent
4 min read
Accidental find may help scientists resolve which evolved first: ability to produce oxygen by photosynthesis or consume it by aerobic metabolism
For biochemists, it’s the which-came-first question: oxygen production by photosynthesis or oxygen consumption by aerobic metabolism?
In photosynthesis, algae and plants take in sunlight to turn carbon dioxide and water into fuel for growth, releasing oxygen as a byproduct. Animals, on the other hand, use oxygen to convert the fuel they consume into energy and emit carbon dioxide, a process called aerobic metabolism.
So which came first? A new paper in the Proceedings of the National Academy of Sciences details an accidental discovery by an international consortium of researchers of a possible missing-link molecule that may lead to an answer to the evolutionary question.
“Right from the start we had this idea that this might be related to the evolution of photosynthesis and the ability to breathe oxygen,” said Felix Elling, a former postdoctoral fellow in the Department of Earth and Planetary Sciences and lead author on the paper.
Elling, who was working in Professor Ann Pearson’s Lab for Molecular Biogeochemistry and Organic Geochemistry, was looking for specific molecules unrelated to questions about the evolution of aerobic metabolism when he discovered something unusual: a slight change in a molecule in a nitrogen-utilizing bacterium, Nitrospirota, that appeared more like something that a plant would need for photosynthesis, rather than a bacterium.
“We were screening bacteria for a completely different project,” said Elling, who is now on the faculty at the University of Kiel in Germany.
What the researchers had found was methyl-plastoquinone, a variation on a molecule type called a quinone. Found in all life forms, quinones had been thought to exist in two basic varieties: aerobic quinones that require oxygen and anaerobic ones that do not.
Aerobic quinones further subdivide into two types — ones used by plants to perform photosynthesis and another used by bacteria and animals to breathe oxygen.
“Basically, all forms of life use quinones for their metabolism,” explained Elling. Finding a quinone, “which is similar to what plants use to perform photosynthesis,” in a bacterium that breathes oxygen was highly unusual. Methyl-plastoquinone, the researchers realized, was a third type, and possibly a missing link between the two.
“This molecule is a time capsule. A living fossil of a molecule that has survived over more than 2 billion years.”
Felix Elling
The research sheds light on what is called the Great Oxidation Event. That period — roughly 2.3 to 2.4 billion years ago — marked when cyanobacteria (a type of algae) began generating significant quantities of oxygen as a result of photosynthesis, making aerobic metabolism possible.
While that development would seem to imply that photosynthesis came first, the discovery of methyl-plastoquinone supports another hypothesis. Simply put, some bacteria already had the ability to utilize oxygen — even before cyanobacteria began producing it.
In other words, “the chicken and the egg were at the same time,” Elling said.
Pearson, the PVK Professor of Arts and Sciences and Murray and Martha Ross Professor of Environmental Sciences, in whose lab Elling’s research began, stressed that having a biochemical processing system for oxygen at the advent of its generation by photosynthesis was a huge step.
“The reactions that involve oxygen are very damaging and can be quite deadly to cells that lack mechanisms to cope with the metabolic byproducts,” she said. Although we take them for granted, “the chemical systems that we all employ in our cells to survive our aerobic metabolic lifestyle are actually quite sophisticated.”
Put simply, “this is how we learned to breathe,” Pearson said. “And once you can breathe oxygen and do it safely, it paves the way for the diversification of all the life we see around us.”
Traces of the diversification of quinone structures can be found in our own bodies, including the fundamental distinctions between quinones in human mitochondria, compared to those in plants.
“We think what we found is the primary or ancestral form of this molecule that then later was adapted to have two forms — one with specific functions in the algae and plants, and the alternative form in mitochondria that we have today,” said Elling.
“This molecule is a time capsule,” said Elling. “A living fossil of a molecule that has survived over more than 2 billion years.”
This research was funded in part by the U.S. National Science Foundation.
Nation & World
‘Existential questions’ around U.S. climate policy, but resolve, too
Analysts weigh in on Paris withdrawal and other early moves by Trump administration
Alvin Powell
Harvard Staff Writer
February 21, 2025
5 min read
Actions by the Trump administration will almost certainly slow the shift from fossil fuels to cleaner energy sources, but they won’t halt it, and energy in
‘Existential questions’ around U.S. climate policy, but resolve, too
Analysts weigh in on Paris withdrawal and other early moves by Trump administration
Alvin Powell
Harvard Staff Writer
5 min read
Actions by the Trump administration will almost certainly slow the shift from fossil fuels to cleaner energy sources, but they won’t halt it, and energy innovation will continue abroad if not in the U.S., Harvard climate experts say.
The new president has moved swiftly to undo the climate efforts of his predecessors, including through an executive order initiating the yearlong process of withdrawing the U.S. from the Paris Climate Agreement, which provides a framework for nations to cooperatively attack warming. The administration has paused permits for new wind power installations, indicated it would remove incentives for electric vehicle purchases, and is attempting to claw back funds awarded to contractors under the 2022 Inflation Reduction Act, which included significant climate change provisions. It has also aggressively moved to reduce staff in federal agencies, including those tasked with fighting climate change.
“We are living in a very uncertain time and a somewhat dark time,” said Daniel Schrag, Sturgis Hooper Professor of Geology, professor of environmental science, and engineering and professor of public policy. “From my perspective, there are existential questions: Will the Trump administration try to block all funding for all climate science? Will climate science happen in the U.S. with federal funding anymore?”
Schrag was speaking Wednesday as moderator of a conversation organized by the Salata Institute for Climate and Sustainability. He was joined at the event by Elaine Buckberg, a senior fellow at the Salata Institute and former chief economist for General Motors; Jody Freeman, the Archibald Cox Professor of Law and director of Harvard Law’s Environmental and Energy Law Program; and Robert Stavins, A.J. Meyer Professor of Energy and Economic Development at the Kennedy School.
An appropriate analogy in recent U.S. history for climate policy may be the path taken by the Affordable Care Act, Buckberg said. Passed in 2010 after highly partisan debate, the ACA survived years of court cases and intense political warfare, emerging with some provisions altered but largely intact. Today it supports health insurance for some 45 million Americans while rancor over the law has eased.
“If you look at, for example, the EV transition — though I think this would apply to solar and other things — I think it’s simply irreversible,” Buckberg said. “You’re talking about changing timing. I think it’s irreversible because it’s a superior technology that’s on a path to becoming less expensive. There is also global regulatory pressure. It is a global auto industry. You cannot stop that progress. What you may impact is what’s the mix in sales in the U.S. in the next few years and who is selling them.”
Freeman suggested that the administration will target California’s exemption from federal vehicle pollution standards as a way to stop the state from setting more stringent standards that favor adoption of electric vehicles. It also appears, she said, that the president will target the “endangerment finding,” a 2009 EPA ruling that underlies the authority of government agencies to regulate carbon dioxide and other greenhouse gases.
“This is a swinging-for-the-fences, maximalist, hyperaggressive strategy that the administration is clearly adopting,” Freeman said. “So this is a maximalist, Article II, presidential-authority set of actions.”
She added: “The way that is unfolding is just stunning, with tremendous harm to things that people care about. But we haven’t yet seen the public health impacts and the day-to-day impacts of slashing and burning through the federal government.”
Addressing the U.S. withdrawal from the Paris climate deal, Stavins said that the global impact of the decision remains to be seen. For now, the absence of U.S. pressure will reduce momentum toward more ambitious goals by other nations, he said. Also, the likelihood that U.S. climate finance payments to developing countries will cease may affect the contributions of other governments. Already, Stavins noted, there’s evidence that three other countries, Indonesia, Argentina, and New Zealand, are considering withdrawing from Paris.
If enough countries pull out, he said, the Paris deal could collapse. While that would stall global advances in the near term, it might create new opportunities for swifter action, he said. The slow pace of progress under Paris has drawn criticism, and a follow-up accord with fewer nations, like the G20 — which represents a large part of the global economy and the vast majority of greenhouse gas emissions — might lead to faster, more substantive change, Stavins said.
“It’s possible that if the Paris agreement did actually collapse, that we would see countries turning to a different approach that might be more effective.”
Clearly, the climate problem isn’t going away, and despite the shift in U.S. policy, other nations — and global industries — will press forward, the panelists agreed.
“I’m not ready to throw in the towel and say it’s all done,” Schrag said. “We have lots and lots of work ahead of us and this effort on climate change doesn’t stop no matter what happens in the next few years of the Trump administration.”
Health
Eating citrus may lower depression risk
Physician-researcher outlines gut-brain clues behind ‘orange a day’ finding
Saima Sidik
Harvard Correspondent
February 21, 2025
5 min read
New findings add another dimension to “gut feelings.”
Eating an orange a day may lower a person’s depression risk by 20 percent, according to a study led by Raaj Mehta, an instructor in medicine at Har
Physician-researcher outlines gut-brain clues behind ‘orange a day’ finding
Saima Sidik
Harvard Correspondent
5 min read
New findings add another dimension to “gut feelings.”
Eating an orange a day may lower a person’s depression risk by 20 percent, according to a study led by Raaj Mehta, an instructor in medicine at Harvard Medical School and a physician at Massachusetts General Hospital. That might be because citrus stimulates growth of Faecalibacterium prausnitzii (F. prausnitzii), a type of bacteria found in the human gut, to influence production of the neurotransmitters serotonin and dopamine — two biological molecules known to elevate mood.
In this edited conversation with the Gazette, Mehta discusses key takeaways from the study.
What inspired this study?
I was working with a fantastic postdoc named Chatpol Samuthpongtorn, who was reading through the literature on depression, looking for an interesting project to take on. And he came across this one paper from 2016 that pointed to the possibility that citrus lowers the risk of depression.
“The effect seems to be specific to citrus. When we look at people’s total fruit or vegetable consumption, or at other individual fruits such as apples or bananas, we don’t see any relationship between intake and risk of depression.”
That piqued our interest because we had access to a rich data set that we could use to follow up on this finding. It’s called the Nurses’ Health Study II (NHS2), and it began in 1989 with the goal of finding risk factors for major chronic diseases in women. It involves over 100,000 women, and roughly every two years they provide researchers with detailed information about their lifestyle, diet, medication use, and health. So we decided to leverage these data to look for evidence that nurses who ate a lot of citrus had lower rates of future depression than those who did not. And that’s what we found!
How big an effect is this? Does it compare to traditional antidepressants?
We found that eating one medium orange a day may lower the risk of developing depression by about 20 percent. And the effect seems to be specific to citrus. When we look at people’s total fruit or vegetable consumption, or at other individual fruits such as apples or bananas, we don’t see any relationship between intake and risk of depression.
It’s hard to compare the effectiveness of citrus to traditional antidepressants, such as selective serotonin reuptake inhibitors, because we’re talking about preventing depression, and those drugs are usually used to treat depression once a person is already experiencing it. In the future, eating citrus could perhaps be part of a strategy for managing depression that also involves these more traditional pharmaceuticals. But more research is needed before we can conclude that.
“I think people know intuitively that the foods we eat impact our mood. We even have a term for this: comfort foods.”
So walk me through the logic. How exactly do you think eating oranges lowers the risk of depression?
One unique part of the study is that a subset of participants in the NHS2 gave researchers several samples of their stool over the course of a year. Using DNA sequencing results from these stool samples, we looked for links between citrus intake and particular species of bacteria in the gut microbiome. One species of bacteria stood out — F. prausnitzii was more abundant in people who were not depressed than people who were, and consuming a lot of citrus was also associated with high levels of F. prausnitzii. So we think this bacterium may link citrus consumption with good mental health.
Because the NHS2 only includes women, we wanted to confirm the findings in a study involving men. So we turned to a similar study, called the Men’s Lifestyle Validation Study, where we also saw increasing levels of F. prausnitzii were inversely correlated with depression risk scores.
So then the question became, how is F. prausnitzii making people feel better? One answer, we think, might be that these bacteria use a metabolic pathway known as the S-adenosyl-L-methionine cycle I pathway to influence levels of two neurotransmitters — serotonin and dopamine — produced by human cells in the gut. These neurotransmitters regulate how food passes through the digestive tract, but they can also travel to the brain, where they elevate mood.
Were you surprised by the findings?
Yes and no. There’s so much evidence now suggesting a strong link between the gut and the brain that I was not surprised to find more. At the same time, I had not associated citrus with the brain before we got these results. You often hear that fish is “brain food,” but nobody says that oranges are brain food. Similarly, F. prausnitzii has been linked to good health in lots of ways, like by lowering the risk of developing inflammatory bowel disease. But I wasn’t aware of a link between F. prausnitzii and mental health.
What’s next for this research?
I would love to see a clinical trial done to definitively show that eating citrus can lower the risk of depression, or maybe even alleviate the condition in some cases. There’s such a huge unmet need for depression treatments, and eating citrus doesn’t really have any major side effects, so it would be great to see how much this simple treatment can help.
More broadly, I hope our results inspire other researchers to look into the link between diet and mental health. I think people know intuitively that the foods we eat impact our mood. We even have a term for this: comfort foods, which make ourselves feel better in the short term. But researchers are just starting to understand the specifics.
The Nurses’ Health Study II was funded by the National Cancer Institute, National Institutes of Health.
Photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
4 things we learned this week
Sy Boles
Harvard Staff Writer
February 20, 2025
1 min read
How closely have you been following the Gazette? Take our quiz to find out.
AI is already changing the job market; doctors are people too; the digital divide is about more than internet access; support for the rule of law goes b
How closely have you been following the Gazette? Take our quiz to find out.
AI is already changing the job market; doctors are people too; the digital divide is about more than internet access; support for the rule of law goes beyond merely not breaking it.
Political scientist, historian examines why so many embrace ‘magical thinking that crowds out common sense and expertise’ in new book
long read
Excerpted from “Ignorance and Bliss: On Wanting Not to Know” by Mark Lilla, M.P.P ’80, Ph.D. 1990, which was published in December by Farrar, Straus and Giroux.
The faintest of all human passions is the love of truth. — A. E. Housman
There was a man who lived in a cave. He did not know that’s where he lived, because his legs had been chained to the ground and his head was enveloped by a device that projected a virtual life not his own. One day an unknown woman removed the device and unlocked the chains, and he saw for the first time where he and many others actually were. He was shattered. The woman comforted him as best she could and said she was there to take him away. As he was preparing to leave, the man noticed a young boy who had been sitting next to him, his legs also bound, his small head invisible inside the grotesque machine. Out of pity he asked the woman if he could take the boy along. She agreed, and they departed.
The climb out of the cave was difficult. When they emerged, the man and boy found themselves in a light so intense that at first they could hardly open their eyes. Little by little, as their vision adjusted, they began to see vague forms illuminated by the sun. These forms, though difficult to describe, were somehow pleasing. The woman called them Ideas and explained that they, and only they, “truly are,” and that all else is illusion. Neither the man nor the boy understood what she was saying, but they found it, too, somehow pleasing. The woman left and did not return for several years.
When she did, she made a request. Now that the man had been freed and lived happily in the light, would he be willing to return to the cave and bring someone else out, just as she had done for him? He agreed and said he would take the boy down with him. But the next morning, after thinking back on the hardships of the first journey, he decided to go alone. He could do the work himself, so why make the boy suffer and deprive him of time in the sun? He called the boy over and announced the good news: he would be staying behind.
The boy began to weep, softly at first, then in earnest. The man was touched by his devotion but told him he should remain in paradise. The boy then fell to his knees and grabbed the man’s cloak, pleading, No, no, you must take me back! I can’t live here any longer. I hate it. The man was stunned. He asked what was wrong, and the boy began to pour out his grievances between sobs:
I’m always cold here. The light is bright, but generates no heat. It reveals everything to my eyes, but doesn’t warm my body. It is so strong that all the colors are washed away; the Ideas are like bleached skeletons, like death. I miss shadows, the night sky, the stars, even if they were illusions.
I can’t sleep. Back in the cave I would sometimes dream at night of things I’d never seen, imagining myself in unknown places doing unexpected things. Now I no longer dream. I know too much. I know what is and that nothing else can ever be real. Isn’t that terrible? How can you stand it?
I’m sad all the time. And I miss my playmates, even if they were just pixels on a screen. Here, no one plays or pretends or even tells a joke. What would be the point? You don’t love me, I don’t love you: we know too much even for that. I want to go home.
And so he did
Just as we can develop a love of truth that stirs us within, so we can develop a hatred of truth that fills us with a passionate sense of purpose.
Aristotle taught that all human beings want to know. Our own experience teaches us that all human beings also want not to know, sometimes fiercely so. This has always been true, but there are certain historical periods — we are living in one — when the denial of evident truths seems to be gaining the upper hand, as if some psychological bacillus were spreading by unknown means, the antidote suddenly powerless. Mesmerized crowds follow preposterous prophets, irrational rumors trigger fanatical acts, and magical thinking crowds out common sense and expertise.
One can always find proximate causes of such surges in resistance to truth, whether historical events or social changes or new intellectual and religious currents promising a holiday from reality. The source lies deeper, though, in ourselves and in the world itself, which takes no heed of our wishes.
The world is a recalcitrant place, and there are things about it we would prefer not to have to recognize. Some are uncomfortable truths about ourselves; those are the hardest to accept. Others are truths about outer reality that, once revealed, steal from us beliefs and feelings that have somehow made our lives better, easier to live — or so we think. The experience of disenchantment is as painful as it is common, and it is not surprising that a verse from an otherwise forgotten English poem became a common proverb: Ignorance is bliss.
We can all come up with reasons why we and others avoid knowing particular things, and many of those reasons are perfectly rational. A trapeze artist, just before climbing the pole, would be unwise to consult the actuarial table for those in her line of work; a young poet should pass up the chance of asking an older one what she thinks of his verses. Even the question Do you love me? should not trip off our tongues, but rather pass through several checkpoints before being uttered. If we knew what every person thought of us at every moment (imagine a small LED screen embedded in every forehead, relaying every thought), we would not only feel paralyzed before them; we would also have trouble attaining any independent sense of ourselves, free from the opinions of others. Even self-knowledge, the beginning of wisdom, depends on resisting at least this kind of knowledge about the world.
So in particular cases we all have instrumental reasons for avoiding the truth, the whole truth, and nothing but the truth. Our lives, though, are not made up of a string of discrete, unrelated moments in which we decide to seek knowledge about one thing, then decide not to seek it about another. Life is not an assembly-line job where we are tasked with sorting experiences into one box or another — want to know, don’t want to know — as they chug down the conveyor belt. We all have a basic disposition toward knowing, a way of carrying ourselves in the world as experiences come our way. Some people just are naturally curious about how things got to be the way they are; they like puzzles, they like to search things out, they enjoy learning why. Others are indifferent to learning and see no particular advantage to asking questions that seem unnecessary for just carrying on. And then there are people who, for whatever reason, have developed a particular antipathy toward the search for knowledge, whose inner doors are fastened tight against anything that might cast doubt on what they believe they already know. We have all met people with these basic attitudes. Most of us have also fallen into moods where they emerge in ourselves, however uncharacteristically.
Knowing is an emotional experience. It is not simply a matter of the senses sending messages to the brain, synapses firing, propositions being formed and their logic tested. The desire to know is exactly that, a desire. And whenever our desires are satisfied or thwarted, our feelings are engaged. Even in trivial matters, we feel something about what we learn. Say, for example, a toaster I own breaks and needs to be fixed. I look at the manual, I watch videos, I ask questions, I tinker, and with any luck I learn how to make it work again. I feel satisfied, and doubly so. Not only can I use the machine again, I have also confirmed my sense of being the kind of person who can seek knowledge, find it, and use it. Toast and self-satisfaction: not a bad way to start the day.
But there is also the contrary disposition: the will not to know, the will to ignorance.
Socrates asserted that the unexamined life is not worth living for a human being — from which it does not follow that the relentlessly examined life is.
It was Nietzsche who coined the term, and his description of being in its grip is unforgettable. Opposed to the drive to knowledge, he wrote, is:
an apparently opposite drive, a suddenly erupting decision in favor of ignorance, of deliberate exclusion, a shutting of one’s windows, an internal No to this or that, a refusal to let things approach, a kind of state of defense against much that is knowable, a satisfaction with the dark, with the limiting horizon, a Yea and Amen to ignorance.”
Nietzsche was a hyperbolic thinker and writer, but in this case he was exaggerating nothing. There are people whose disposition toward seeking knowledge can grow weaker or stronger depending on their mood or circumstances. And then there are those whose basic psychological posture, so to speak, is to resist new knowledge. Just as we can develop a love of truth that stirs us within, so we can develop a hatred of truth that fills us with a passionate sense of purpose. If that seems an alien notion, consider this passage from Pascal’s “Pensées” and ask yourself if it doesn’t capture a feeling that has welled up within you at some point, or if it is an attitude you have observed in others:
The self wants to be great, and sees itself small; it wants to be happy, and sees itself wretched; wants to be perfect, and sees itself full of imperfections; it wants to be the object of men’s love and esteem, and it sees that its defects deserve only their dislike and contempt. This embarrassment in which it finds itself produces in it the most unrighteous and criminal passion imaginable, for it conceives a mortal hatred against this truth, admonishing it and convincing it of its faults. It wants to annihilate this truth, but, unable to destroy it in its essence, it destroys it as far as possible in its own knowledge and in that of others.
Resisting knowledge is an emotional experience, too.
Living in the shadow of the modern Enlightenment, we are accustomed to hearing curiosity extolled for the material benefits it brings and for the contribution it makes to what we today consider our most precious possession: inner freedom. For just that reason, perhaps, we are less accustomed to observing and reflecting on curiosity as a purely psychological drive charged with unruly passions. There is of course a long tradition of thinking that looks askance at the human passion for knowing and raises doubts about its value for life. Reasons can be given for the desire to know; reasons also can be given for constraining that desire.
But apart from this clash of reasons there is also a clash of unreasoning emotions, with the desire to defend and even cultivate our ignorance standing as a powerful adversary to the desire to escape it. Once one learns to recognize this clash of wills, one begins to see what an important role it plays in our individual and collective lives, and especially in how we think about those lives. As George Eliot put it: It is a common sentence that Knowledge is power; but who hath duly considered or set forth the power of Ignorance?
In my experience, the deepest treatments of the will to ignorance are to be found in works of the Imagination — ancient myths, religious scriptures, epic poetry, plays, and modern novels. This should probably come as no surprise: without the capacity to resist seeing what is right before our eyes, there would be no drama in human life, no movement. A story about someone who discovers that a truth has been kept from him by someone else reveals nothing particularly interesting about what it is to be human (except that some people are liars). A story about someone who has kept the truth from himself immediately becomes a work as complex as any watch, with innumerable gears and springs that labor just below the surface of a deceptively lethargic face.
In exposing the ruses of the will to ignorance, literature exposes us to ourselves, which is sufficient for its purposes. What we lack — or at least what I found lacking for my own purposes — is a nonpoetic reflection on the will to ignorance and its polymorphous role in human existence. How is it that we are creatures who want to know and not to know? How is it possible for both desires to inhabit the mind? What function does resistance to knowledge serve in shaping our emotions, our self-understanding, and our understanding of the world around us? How has it influenced our common life, our religions, and our cultures? And what does it mean for how we should live? Socrates asserted that the unexamined life is not worth living for a human being — from which it does not follow that the relentlessly examined life is. Where does that leave us? These are some of the questions I propose to explore.
Throughout it will be good here to return to the story I began with, a parody of Plato’s “Allegory of the Cave.” The little boy does know what knowing is like — and that is why he wants to escape. His is a knowing will to ignorance. I imagine him first emerging from the cave baffled and a little scared, but, like all youngsters, intrigued by a new place to explore. I imagine him looking at the Ideas and sometimes enjoying the feeling of having understood. And yet he snaps. The world as it truly is does not welcome him; it looms, oppressively. The price of living this way is too high. He wants to flee and forget what he already knows. He wants a different kind of life from the one that has been thrust upon him. Plato spoke of the eros of intellect; the young man is in the grip of the thanatos of intellect. If we do not understand both, we do not understand ourselves.
We want to know, we want not to know. We accept truth, we resist truth. Back and forth the mind shuttles, playing badminton with itself. But it doesn’t feel like a game. It feels as if our lives are at stake.
Nation & World
What jazz teaches about necessity of civil discourse
Musician, composer Wynton Marsalis visits campus to help launch Culture and Civil Society Initiative
Christina Pazzanese
Harvard Staff Writer
February 19, 2025
4 min read
Wynton Marsalis. Veasey Conway/Harvard Staff Photographer
Jazz offers an important lesson on the vital importance of civil discourse, according to j
What jazz teaches about necessity of civil discourse
Musician, composer Wynton Marsalis visits campus to help launch Culture and Civil Society Initiative
Christina Pazzanese
Harvard Staff Writer
4 min read
Wynton Marsalis.
Veasey Conway/Harvard Staff Photographer
Jazz offers an important lesson on the vital importance of civil discourse, according to jazz great Wynton Marsalis.
“If I’m playing in a rhythm and you’re playing a totally different rhythm, we’re not going to agree,” said the acclaimed composer and musician last week at a campus event. “Not only are we not going to agree, we’re not going to sound good. And if we don’t have the same understanding of what we’re trying to do on the bandstand, we’re going to have hard time.”
And, he said, when musicians agree less and less on what constitutes their common musical history, they lose the language that connects them.
A longstanding advocate for arts education and for wider recognition of jazz and its contributions to American culture and history, Marsalis spoke on Feb. 10 with Anthony Foxx, co-director of the Center for Public Leadership and the Emma Bloomberg Professor of the Practice of Public Leadership at Harvard Kennedy School, to launch the Culture and Civil Society Initiative.
A similar foundational agreement to the one that makes jazz possible undergirds this country, said Marsalis, who is managing and artistic director of Jazz at Lincoln Center. “If we cannot agree that the Constitution is a document that is designed to create agency for others and that it is a leveling document, we can’t have a democracy.”
There are some in the nation focused on “dismantling democracy with chaos and creating a working class that is disenfranchised — [they hope] all over the world,” so that everything “can be turned over to corporations who have done nothing to show you that they are trustworthy,” he said.
Marsalis, 63, broke out in the early 1980s as a trumpet-playing prodigy, winning Grammys in both jazz and classical music in 1983 and 1984, a historic first. In 2009, Harvard presented him with an honorary Doctor of Music. From 2011-2012, he gave a series of performances and lectures on music at Sanders Theatre.
Marsalis was on campus last week to help launch the new research and teaching program at CPL. The initiative seeks to harness the power of arts and culture to fortify democratic institutions and encourage civil dialogue. Foxx said the idea for the program evolved from his conversations with Marsalis.
Marsalis said he was not alarmed that today’s partisanship might irreparably divide Americans because he sees this as a clash over power and economics that’s been going on in the U.S. for centuries.
“I’m always optimistic because I understand what our history has been. We’re still fighting the Civil War; and now, the South is ahead,” he said.
As a young horn player, he recalled receiving valuable lessons from seasoned pros like his father, the late pianist Ellis Marsalis. He tries to offer similar guidance to students at his alma mater, Juilliard, where he is now director of jazz studies.
“I always say, take yourself seriously; take what you think seriously; take what you feel seriously; take your power seriously; take your word seriously. These are always serious times, and not because of any new president,” but because fighting for human rights and for everyone to have an equitable life is an “uphill battle” that never ends.
Marsalis could have become a classical music star (he has recorded 20 classical albums) but said he had little doubt about his career path, having grown up in a family of jazz musicians. For those students who aren’t sure which creative path to follow, however, he encourages them to write a mission statement.
“It’s three sentences: What I want to do, through what means am I going to do it, and why do I want to do it? And I tell them, work on this like it’s a poem to yourself and take words out of it. And just study it,” he said. As musicians, “we’re always studying other people — Charlie Parker or [Thelonius] Monk. It’s important to study other people, but study yourself and get to what you really want to do.”
Marsalis batted away the suggestion that jazz carries some extra historical or cultural burden because it, like the blues, is born from blood and pain.
“Everything is born in some kind of pain. It is a fact of life. It doesn’t make you able to do anything. A lot of people are in pain. It doesn’t mean they sing like Billie Holiday.” The central question in jazz, Marsalis said, is “can you play? If you can play, play it.”
Nation & World
Who sustains the rule of law?
The question is a personal one for voters, scholar argues — or should be
Christina Pazzanese
Harvard Staff Writer
February 19, 2025
4 min read
Legal and political philosopher Jeremy Waldron.Veasey Conway/Harvard Staff Photographer
The rule of law is often associated with the actions of government officials, prosecutors, and judges, but ordi
The question is a personal one for voters, scholar argues — or should be
Christina Pazzanese
Harvard Staff Writer
4 min read
Legal and political philosopher Jeremy Waldron.
Veasey Conway/Harvard Staff Photographer
The rule of law is often associated with the actions of government officials, prosecutors, and judges, but ordinary citizens also bear responsibility in upholding a society’s ethical and legal principles, says Jeremy Waldron, a professor at New York University School of Law.
A “fragile” but also “valuable and practicable ideal, ” the rule of law imposes on the government a “moral requirement” to legislate respectfully and to enact laws in a way that guides the conduct of citizens, but also “respects the agency” of those affected by such laws, Waldron, a scholar of legal and political philosophy, argued during the Edmond & Lily Safra Center for Ethics’ annual Kissel Lecture in Ethics on Thursday.
For ordinary citizens, support for the rule of law goes beyond merely not breaking it, he said.
“If government and its officials are constrained, then we, as voters and citizens and party members, must be constrained too in what we press for, in what we vote for, in what we pay for and organize for, and in the pressure we put on the state.”
Abiding by the rule of law means using the legal system in good faith, not to settle scores or to gain personal, political, or economic advantage, Waldron added. It also demands patience with officials who work within the often-slow pace and technical nature of the legal process, not to mention tolerance for actions we disagree with.
“If government and its officials are constrained, then we, as voters and citizens and party members, must be constrained too in what we press for, in what we vote for, in what we pay for and organize for, and in the pressure we put on the state.”
“Whenever an adverse decision is rendered to a citizen or an official, they immediately go onto the courthouse steps and say, ‘This is an outrage, and I’m going to appeal,’” he said. “Maybe we shouldn’t immediately denounce adverse decisions on the courthouse steps and move automatically to appeal. Maybe we should gracefully disclose a willingness to reflect on the verdict and consider our options in a responsible manner.”
Waldron noted that citizens help enforce the rule of law in a variety of ways — as jurors, witnesses, and civil complainants. Also as voters, who have an obligation to not allow self-interest to keep them from holding officials accountable, he said.
“If official compliance with law poses costs for the state and thus, for the taxpayer, we should be willing to bear them. Or if it results in missed opportunities for officials to confer benefits on us or lift burdens from us, then it’s incumbent on the ordinary voter not to urge that the rule of law be sidelined for those reasons, nor to acquiesce at it being sidelined, nor to request it being sidelined when officials do violate the rule of law.”
All the ways in which citizens comply with the law, from accepting their preferred candidate’s political defeat to following rules they don’t agree with, provide a model for the type of conduct we should expect from leaders, he argued.
Which is not to say that recent events, including court rulings, haven’t posed challenges to this principle.
For example, the idea that under the rule of law no one is exempt from legal accountability appears to conflict with the Supreme Court’s recent decision on the scope of presidential immunity, Waldon acknowledged.
“Any form of legal immunity is going to be a rule-of-law problem since it exempts some individual or class of individuals from legal obligations that apply to the rest of the community,” he said. The case of presidential immunity is “particularly troubling,” he added, because it affixes “a lack of legal accountability at the visible apex of the state to benefit the highest office holder.”
At the same time, citizens can still “insist that an office holder like the president has a particular obligation to respect all the laws, constitutional and non-constitutional, and to communicate respect for the whole legal enterprise, for all its processes, institutions and requirements,” Waldron said.
“We want what is called the highest power in the land — sometimes the highest power in the universe — to be associated with legality.”
Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Conflict is inevitable. Rancor isn’t.
Liz Mineo
Harvard Staff Writer
February 18, 2025
4 min read
‘Disagree curiously,’ says undergrad nonprofit founder. And she’s not alone.
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
Shira Hoffer’s vocation is rooted in the fami
‘Disagree curiously,’ says undergrad nonprofit founder. And she’s not alone.
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
Shira Hoffer’s vocation is rooted in the family meetings her parents led at their New Hampshire home to deal with conflicts or hard topics. The four would sit on the couch around a bowl filled with M&Ms, which would slowly disappear as they talked.
“I’m predisposed, you could say, to be invested in conflict resolution,” said Hoffer, a senior concentrating on social studies and religion. “Both my parents modeled for us how to give weight to different perspectives and exploring pros and cons and not writing things off immediately.”
Hoffer leaned on those experiences when she launched the Hotline for Israel/Palestine shortly after the Oct. 7, 2023, terror attacks to foster productive dialogue on campus about the war in Israel and Gaza. Her goal was to provide accurate, unbiased answers to questions about the conflict and its long history to help those who had little or no background and might otherwise get information from less-reliable sources.
“Some people told me, ‘You’re platforming the enemy,’ and others would say, ‘You’re supporting genocide,’” said Hoffer of the response to her project. “People had a lot of questions, and we need to nurture those questions, lest people become more close-minded.”
Over the last year, the hotline’s 20 volunteers have answered more than 300 questions, but along the way, Hoffer realized more work was needed.
Last spring, she founded the nonprofit Institute for Multipartisan Education to offer consulting to middle and high schools about how to advance civil discourse and constructive disagreement. A one-year fellowship for college students to do the same on their own campuses will start next fall.
“Humanizing, understanding, and bridge-building are not possible without a degree of curiosity.”
Hoffer’s goal is to help bring about a wider cultural shift that embraces dialogue across differences. It begins with helping students discover how to listen to views different from their own without shunning or canceling those on the other side. The way to do that, she said, is by nurturing curiosity and open-mindedness.
“We’re saying, ‘Disagree, but disagree curiously,’ and see what happens,” said Hoffer. “We want to help students learn the skills to approach difference with curiosity. Humanizing, understanding, and bridge-building are not possible without a degree of curiosity.”
It’s necessary work because people are not often taught how to talk about the most difficult topics, said David Seibel, associate faculty at Harvard Law School’s program on negotiation. An expert in mediation and dispute resolution, Seibel serves on the advisory board of Hoffer’s nonprofit.
“We don’t have a strong platform or foundation or habit for constructive dialogue,” said Seibel, who met Hoffer when she attended a mediation program at the Law School. “Shira’s organization is important because it is a platform for students to focus on how to create meaningful communication in a time when there’s so little of that.”
After graduation, Hoffer plans to devote herself to her nonprofit. In a way, it’s not far from what she expected to do after high school — something between the law and religion.
Attending a pluralistic Jewish high school in Waltham, Massachusetts, where students of Orthodox, conservative, reform, and other denominations of Judaism study together, allowed her to see the benefits of learning about her schoolmates’ differences and building community together, she said.
During her years at Harvard, Hoffer joined the Harvard Interfaith Forum and the Harvard Intellectual Vitality group and took part in several dialogue and conflict-resolution programs. Although she worries about the administrative and fundraising challenges facing nonprofits and startups, Hoffer underscores the importance of her mission of “spreading curiosity across education.”
Even before the Israel-Hamas war, U.S. society was experiencing heightened polarization over issues such as LGBTQ rights, abortion, and immigration. It’s critical to learn how to have conversations across divides for the sake of democracy, said Hoffer.
“Polarization and an unwillingness to understand each other create problems at all levels of society,” she said. “It creates academic problems when in the classroom, people are unwilling to entertain different perspectives on historical or current events. It creates social problems when we become siloed into communities based on our perspectives, and it creates problems for democracy when we’re unable to engage in a conversation with the other side.”
Veasey Conway/Harvard Staff Photographer
Health
Primary care has money problems. This might help.
Physician-researcher sees promise in five-year ‘prospective payment’ experiment
Alvin Powell
Harvard Staff Writer
February 18, 2025
5 min read
Many health experts say that U.S. primary care is in crisis, with demand for appointments rising and doctors scarce. A new five-year experiment might
Physician-researcher sees promise in five-year ‘prospective payment’ experiment
Alvin Powell
Harvard Staff Writer
5 min read
Many health experts say that U.S. primary care is in crisis, with demand for appointments rising and doctors scarce. A new five-year experiment might prove part of the solution.
Set in motion by Affordable Care Act provisions intended to boost financing innovations, the program, ACO PC Flex, will increase primary care spending while incentivizing doctors to use the funds to head off serious illness and expensive hospital visits. The goal, proponents say, is a healthy cycle of better, broader primary care options.
Soleil Shah, a policy researcher and physician at Harvard-affiliated Brigham and Women’s Hospital, co-authored a recent opinion piece on the new initiative in the Journal of the American Medical Association. In this edited conversation with the Gazette, Shah outlines some of the barriers to primary care and details the potential benefits of ACO PC Flex.
What’s wrong with U.S. primary care?
There are a few different factors at play. First is the burden placed on clinicians to see a lot of patients in a short time. This is getting worse. More often than not, primary care practices are owned by large corporate entities like health systems and insurance companies. These corporate entities want clinicians to see as many patients as they can because more volume means more people can be charged.
Second is that reimbursement is quite low for primary care relative to other providers. Our healthcare system prioritizes specialist care and overweights quick office procedures — dermatologists who perform procedures in the office, ophthalmologists who perform cataract surgery — over primary care, whose doctors do annual exams, provide preventative care, and work up acute medical complaints.
Another issue is the volume of medical information that exists today. It’s a lot for anyone to handle, and as data and knowledge grow exponentially, the scope of primary care is expanding rapidly.
“[This model] creates incentives for doctors to spend more time counseling patients and doing other things, outside of traditional clinic appointments, to try to keep them healthy.”
If primary care was valued properly, would practitioners make as much as brain surgeons? ER physicians?
I can’t say what the right number is, but they’d be paid much more than they currently are. Some advocate redoing the fee schedule so that specialists aren’t paid as much and primary care gets paid more. I don’t think that’s likely. For many decades, political societies that represent different specialties have advocated in Congress to keep rates high. Those societies have bargaining power, and primary care has historically not been able to get their rates up in the way that cardiologists and other specialists have.
So to improve primary care in a different way, we’ve created accountable care organizations?
Accountable care organizations are a different model for paying doctors. Their goal is to incentivize doctors to provide high-quality care at lower cost to patients. Under an ACO, doctors get paid as they normally would, which is fee for service. But in an ACO, if they’re able to keep their expenses under a certain threshold — let’s say that threshold is $100,000 and they end up spending $80,000 — then the remainder is considered shared savings. A portion gets paid to providers as an incentive while another portion is retained by government as savings.
The idea of shared savings has become popular and ACOs are a promising area of payment innovation in healthcare. They incentivize doctors to keep patients out of the hospital, where they incur high medical costs. ACOs are a decade old, and the next iteration — a new form of ACO — started in January: ACO PC Flex.
And this new plan increases payment for primary care?
In the typical ACO model, doctors get paid after they provide services. Here, the payment comes before any services are given. This is called “prospective payment,” where the ACO gets a large payment before any care is delivered. That payment is based on the average payment within the county where the ACO is located, with some adjustment if the patients seen by that ACO are medically complex. The amount that they’re planning on paying these groups up front is a huge increase compared to historical levels of payment for primary care doctors. We hope this is going to help these ACOs build more infrastructure around primary care and create special programs focused on keeping patients out of the hospital. It creates incentives for doctors to spend more time counseling patients and doing other things, outside of traditional clinic appointments, to try to keep them healthy.
Also, in typical ACOs, when you administer a service like ordering labs for a primary care patient, that expense counts against your expenditure goal — $100,000 in our prior example — and cuts into your potential shared savings. That might create a disincentive to invest heavily in primary care. The ACO PC Flex model handles it differently, and the upfront payment does not count as an expenditure.
These are design elements that we think will encourage more primary care, that will bring primary care providers’ payments closer to those of other specialties, and, hopefully, incentivize more upstream preventative care.
If it works well, could we see it replacing other primary care reimbursement models?
That is the classic question. These models apply to Medicare enrollees, but, if this is successful, to what extent will it trickle down to people who aren’t on Medicare? If this is good for Medicare beneficiaries, that’s welcome. But we also need more money for primary care providers in Medicaid, especially, because those are lower-income patients and reimbursement rates are lower. Plus, they’re often the patients with the highest need and who would benefit the most from more and better primary care.
Commercial insurance will be incentivized if ACOs see savings through this plan. If this is a successful program, keeping patients out of the hospital and saving money on the total cost of care, then private insurance companies could be interested in implementing something similar.
Members of the cast of “The Odyssey.”Nile Scott Studios and Maggie Hall
Arts & Culture
Star of new ‘Odyssey’ adaptation? Your imagination.
Eileen O’Grady
Harvard Staff Writer
February 14, 2025
4 min read
Puppet designer on power of negative space to provoke emotion — and creating a convincing Cyclops
Kate Brehm knelt behind a backlit screen in a Loeb Drama Center rehearsal room, hold
Star of new ‘Odyssey’ adaptation? Your imagination.
Eileen O’Grady
Harvard Staff Writer
4 min read
Puppet designer on power of negative space to provoke emotion — and creating a convincing Cyclops
Kate Brehm knelt behind a backlit screen in a Loeb Drama Center rehearsal room, holding a shadow puppet of the character Penelope from Homer’s “Odyssey.” Brehm and puppeteer Abigail Baird were discussing the movements required to ensure a sharp silhouette of the puppet during a scene in the A.R.T.’s new stage adaptation of the epic poem.
“Part of the skill of puppetry is to offer just enough information, but not all of it, so that you’re taking advantage of the negative space in between so that the audience can fill it in,” said Brehm, puppetry director and designer for “The Odyssey,” which opens at the American Repertory Theater on Feb. 18.
“Puppets are a blank slate in a way, which sometimes allows for more emotional engagement from the audience. I’m very excited about audience imagination, because what the audience can imagine is better than anything I could make.”
The artifice involved in shadow puppetry dovetails perfectly with a production that reflects on the illusions of heroism created by storytelling, said Brehm, lecturer in Physical Theater in the FAS’ Theater, Dance & Media program.
Written by Kate Hamill and directed by Shana Cooper, the adaptation reimagines the stories of Odysseus (played by Wayne T. Carr) and his wife, Penelope (Andrus Nichols), around themes of healing and forgiveness as ways to end cycles of violence and revenge. While most of the play is performed by live actors, puppets are used in several key scenes.
Niles Singer/Harvard Staff Photographer
“I’m intrigued by the non-verbal information that is conveyed through puppetry,” said Brehm, who has been directing, designing, and performing puppetry and experimental theater works for more than 20 years. “You can really tell difficult stories, stories about trauma, like this version of ‘The Odyssey.’ It makes sense to me to express these difficult ideas in something other than the human.”
Take the scene in which Penelope tells her son Telemachus (Carlo Albán) the story of his father’s departure. As many as five cast members are handling puppets behind the screen, including Nichols and Albán, who are puppeteering while also narrating the story. The actors must think about their puppets’ placement on the screen, how the size of their shadows changes with their proximity to light, as well as the emotions conveyed through their movement.
“It’s very much like choreography,” said Brehm, who is teaching a course titled “Puppet Theater” this semester. “There are two performances going on here. One is the performance the audience sees on the puppet screen, and one is the choreography of the actors and puppeteers behind the scenes, picking up and putting down puppets in precise locations.”
“I’m intrigued by the non-verbal information that is conveyed through puppetry,” says Kate Brehm.
Photos by Niles Singer/Harvard Staff Photographer
A puppet made of plywood.
One piece of the Cyclops’ eye.
Brehm (left) and Abigail Baird project the Cyclops’ eye.
Brehm uses a different illusion to portray the Cyclops’ eye, which appears when the giant Polyphemus (Jason O’Connell) captures Odysseus and his men. Brehm and Waltham puppeteer Sarah Nolen constructed three tiers of plexiglass above an overhead projector so they could manipulate the Cyclops’ eyelid to make it look like it is opening and closing. The eye, which Baird operates with another puppeteer, must be in sync with O’Connell’s performance.
“You have to breathe together and anticipate, and get to know the other performers,” Baird said, likening the experience to being part of an orchestra.
Brehm worked with Nolen to design and build the puppets. About a foot in length, the handheld shadow puppets are made from a combination of thin plywood, styrene, and acrylic, and some have movable joints constructed with wire.
Brehm sees her puppetry work as just one piece in the larger “puzzle” of the show, which she described as “literally epic.”
“What I hope the audience takes away from this show is a larger vision about the myths we create,” Brehm said. “Our capacity to both make them and to change them within our families and our societies. We have the power to make our own stories.”
A study co-authored by economist David Deming examines how technology has changed the U.S. labor market over 100 years.Stephanie Mitchell/Harvard Staff Photographer
Work & Economy
Is AI already shaking up labor market?
4 trends point to major change, say researchers who studied century of tech disruptions
Christy DeSmith
Harvard Staff Writer
February 14, 2025
6 min read
A new paper by
The study measures more than 100 years of “occupational churn” — or each profession’s share in the U.S. labor market — for a historical look at technological disruption. It revealed a stretch of stability between 1990 and 2017 that runs counter to popular narratives about robots stealing American jobs. But the research also uncovered a recent shift, with the authors identifying several trends driven, at least partly, by AI.
“We really thought the paper would say something like, ‘See, I told you so. Things aren’t changing all that much,’” said Deming, the Isabelle and Scott Black Professor of Political Economy at Harvard Kennedy School and Faculty Dean of Kirkland House. “But when we got into the data, we found the story was a bit more subtle — and more interesting in some ways — than anything we expected.”
For years, Deming and Summers had talked about gauging occupational churn in the U.S. labor market over time. “It would be a systematic way to measure how much all these different types of technology have affected work,” explained Deming, the paper’s lead author.
Labor market volatility over last century
Employment share by industry, 1880-2024.
Source: “Technical Disruption in the Labor Market”
Last year the economists applied the metric with help from Kennedy School predoctoral fellow Christopher Ong ’23, the paper’s third author. Their findings, drawn from 124 years of U.S. Census data, originally appeared in a volume published last fall by the Aspen Economic Strategy Group. Summers, a member of the OpenAI board of directors, shared further predictions in a live interview at the Aspen Ideas Festival.
Summers was initially surprised by the level of volatility uncovered in the 1950s, ’60s, and ’70s due to the rise of what are called “breakthrough general-purpose technologies.” “But when I thought about it, it wasn’t surprising,” said the Charles W. Eliot University Professor and Frank and Denie Weil Director of the Mossavar-Rahmani Center for Business and Government at Harvard Kennedy School. “It used to be that only a very limited number of people used keyboards. Now everybody uses keyboards and there are fewer people whose whole job is to use keyboards. That turned out to be a very big structural change that the economy managed.”
The 2000s and 2010s were characterized by what Deming called “automation anxiety.” As evidence, he pointed to an influential study from 2013 asserting that 47 percent of U.S. occupations were at imminent risk of displacement by computers. But the occupational churn metric showed the pace of disruption slowing by 1990 as the labor market entered a stretch of low churn.
Then another surprise appeared in the data. “From 2019 onward,” Deming said, “it looks like things were changing quite a lot.”
“Everybody should be thinking about AI, no matter what they do for a living.”
Lawrence H. Summers, study co-author
Is AI a breakthrough technology along the lines of keyboards, electricity, and computer-based manufacturing? The co-authors’ findings led them to believe so. As evidence, they outline four emerging trends in the U.S. job market.
The first concerns the end of what economists have termed job polarization — a barbell-shaped pattern, with the labor market growing at the top and bottom of the wage distribution.
What appeared more recently, the researchers found, is a one-sided pattern favoring well-compensated employees with high levels of training and skill. “The trend people were worried about in the 2000s was the downward ramp,” Deming said. “That meant low-paid jobs were growing but middle- and high-paid jobs were not. It’s only in the late 2010s that we see an upward ramp, with mostly high-paid jobs that are growing.”
Another trend, related to the first, finds a recent skyrocketing of science, technology, engineering, and math jobs following a surprising dip in the 2010s. The share of jobs in STEM — including software developers and data analysts — grew from 6.5 percent in 2010 to nearly 10 percent in 2024. “That doesn’t sound like a lot,” Deming said. “But it’s an almost 50 percent increase.”
Analyzing data sourced from the Census as well as the Federal Reserve Bank showed firms are not only hiring more technical talent, they’ve started to make record-breaking investments in frontier technologies such as AI. “You really don’t need to speculate about AI’s impact on the labor market,” Deming noted of these findings. “Investment in AI is already changing the distribution of jobs in the economy.”
The research also uncovered flat or declining employment specifically in low-paid service work. Charting the occupational churn in this sector, which saw enormous growth from 1980 to the early 2000s, revealed a cliff as of 2019. AI is just one possible explanation, Deming emphasized. Other contenders include higher wages, a tighter job market, and temporary disruptions related to COVID-19.
“But it doesn’t look like many of these jobs are coming back,” Deming added. “The ones that have returned are in food service, personal services like manicurists and hairdressers, medical assistants, and some cleaning jobs.”
The paper’s fourth trend suggests an especially deep plummet, driven by technology, in retail sales jobs. Between 2013 and 2023, the share of retail sales jobs dropped from 7.5 to 5.7 percent of the job market, a reduction of 25 percent.
The co-authors note that the e-commerce sector was an early adopter of predictive AI, and has more than doubled its share of all retail sales since 2015.
“I see the pandemic as an accelerant, as something that was going to happen anyway,” Deming said. “When people were told it’s dangerous, possibly even deadly, to go shopping — now they had to shop online — they discovered it actually wasn’t so bad and formed new habits.”
“Everybody should be thinking about AI, no matter what they do for a living,” Summers added. “Because AI can be highly empowering. But it also means certain types of activities won’t be done by people anymore.”
The paper contains a nugget of insight for knowledge workers in sectors like finance, management, and journalism. Automation has indeed claimed American jobs over the last century. In a Substack post, Deming cited the early 20th-century example of telephone operators. But AI’s impact is more likely to enable short-term boosts to productivity with longer-term threats of displacement by workers more adept with the technology.
“When companies start to get squeezed — when we hit the next recession or something — they’re going to start expecting more out of knowledge workers,” Deming said. “They won’t want that memo in two days, because they know this technology is available. They’ll want it in two hours.”
Karen Thornber.Photo by Grace DuVal
Campus & Community
New era for the Bok Center
Eileen O’Grady
Harvard Staff Writer
February 14, 2025
8 min read
Director shares vision for innovative teaching and learning
As Karen Thornber envisions the next chapter for the Bok Center, connection, collaboration, and innovation are her guiding principles.
Since Hopi Hoekstra, the Edgerley Family
Director shares vision for innovative teaching and learning
As Karen Thornber envisions the next chapter for the Bok Center, connection, collaboration, and innovation are her guiding principles.
Since Hopi Hoekstra, the Edgerley Family Dean of the Faculty of Arts and Sciences, appointed Thornber to the role of Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning in July, the Harry Tuchman Levin Professor in Literature and Professor of East Asian Languages and Civilizations has set her sights on expanding the reach and deepening the impact of the center, which has served the Faculty of Arts and Sciences community for 50 years.
For Thornber, who also co-chairs the FAS Civil Discourse Advisory Group and serves on the Generative AI Faculty Advisory Committee, fostering constructive conversations about difficult topics in the classroom and reimagining teaching in the age of AI are also top priorities.
“My vision is for the Bok Center to become a leading and integrated center for innovative teaching and learning,” Thornber said. “We have big goals, big aspirations, and I think we’re definitely on track for succeeding in this endeavor.”
In this edited conversation with the Gazette, she discusses her vision for the center’s future.
You’ve been in this role for six months so far. What pre-existing work have you been building upon, and what are your primary goals moving forward?
In the past, the Bok Center had been very good at working with faculty who were already exceptional and who wanted to take their teaching to an even higher level, creating exquisite and bespoke courses. The center was also really great at working with faculty and teaching fellows who were truly struggling in the classroom and getting them to a place where they could be more successful. My goal and our mission is to partner with all members of the FAS teaching and learning community, from the undergrad course assistants and graduate student teaching fellows to non-ladder faculty, tenure-track, and tenured faculty, and to continually reimagine and adapt courses and teaching, learning, and professional growth more broadly.
I’m fortunate to have a nimble, forward-thinking staff eager to be a part of Bok’s dynamic future. In the coming months we’ll be hiring extraordinary individuals who can help propel the center to a more central position in the FAS and University. We are absolutely committed to collaborating, so we’ve been working very assiduously with FAS leadership, the Office of Undergraduate Education, the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences, the Office for Faculty Affairs, and other units across the FAS.
“We have big goals, big aspirations, and I think we’re definitely on track for succeeding in this endeavor.”
How are you hoping to expand the way Bok serves faculty?
One thing I’m really excited about is creating a faculty advisory committee that will help me keep a pulse on what’s on faculty minds and assist me in determining priorities for the Bok Center. I’d like to make the Bok Center more accessible to a broader range of faculty, and one fundamental way to do this is to have a website that is a go-to source for concise guidance on all aspects of teaching, from course design to facilitating difficult discussions, and teaching in the age of AI. We’re also planning several speaker series, one of which will feature faculty sharing strategies and best practices with one another. And I think the Bok Center can improve its role in the new faculty orientation, introducing new faculty to teaching resources at Harvard and innovations in pedagogy. Last fall I visited a lot of peer teaching and learning centers to get a better sense of what excites folks in this field. From these visits, I took away many inspiring ideas, from new programming to ideas of how to engage more faculty.
And how are you planning to engage graduate students and teaching fellows?
We’re partnering with the Safra Center, the OUE, GenEd, and GSAS to develop new trainings for our teaching fellows — we rolled out the pilot program in January. Any first-time teacher needs some training and it’s now required for GenEd TFs — a major milestone in the TF training landscape. My hope is to expand this program to all TFs in future semesters. We’re also working with the OUE and GSAS to restructure the Pedagogy Fellows Program so departments will receive the support they need in running pedagogy seminars and providing guidance to TFs. We are additionally reviewing our Bok Teaching Certificates, which are very popular with Harvard graduate students but could become more rigorous and more integrated with departments and GSAS. This spring, we are running several new Bok Seminars including “Community and Civic Engagement in the Classroom,” with the Mindich Program in Engaged Scholarship. Another one, “Beyond the Classroom: Practical Tools for Teaching,” is focused on the actual, practical part of what happens in teaching — it’s going to be much less theoretical than in the past, because our current environment really demands that.
How can undergraduates get involved in the Bok Center?
Undergraduates have long been involved as Learning Lab Undergraduate Fellows (LUFFs), who bring fresh, incisive perspectives on media production, instructional design, and research. We also have Culture and Communication Consultants who work as course assistants in some Bok courses, offering feedback on teaching and language skills to our international scholars. Finally, we have Undergraduate Pedagogy Fellows, who work on programming related to equity and inclusivity in the classroom. We’re rethinking a lot of these programs, but one possibility is something I learned about while visiting Dartmouth and Barnard: course partners. These are undergrads who shadow a faculty member’s course and give candid feedback and advice on how to further engage undergrads or make the material more exciting and accessible. This is just one idea, but I’m excited about exploring this and other new ways to engage our undergraduates.
What work is the center doing to foster civil discourse on campus?
Civil discourse is at the heart of successful teaching and classroom engagement. It’s clear to us that nurturing the ability to foster and manage difficult conversations is an important part of teacher training. In January we partnered with the Safra Center, OUE, and GSAS on TF training that highlighted strategies to foster civil discourse. And in February we welcomed Matthew Sohm as the Bok Center’s first assistant director of civil discourse and classroom culture. Matthew is collaborating with faculty and TFs to create an open classroom culture for students to engage respectfully and collaboratively with different and novel viewpoints. His work addresses a culture of self-censorship, silence, and premature consensus that many students have identified as impediments to their pursuit of a liberal arts and sciences education at Harvard. Other Bok staff, including Chloe Chapin, Sarah Emory, and Jonah Johnson, have also been integrating civil discourse approaches into their areas of expertise.
“It’s clear to us that nurturing the ability to foster and manage difficult conversations is an important part of teacher training.”
This spring, we’ll be partnering with the Safra Center on a series of talks relating to civil discourse. We plan to build a robust civil discourse webpage as a faculty resource. A longer-term project is working with Education Support Services on classroom design and infrastructure. You need to have flexibility in your classroom space, whether we’re talking AV or the way the desks and chairs are placed. It’s hard to have a really meaningful conversation in a large lecture hall, just because of the way the chairs are configured. Loneliness and disconnection negatively impact students’ ability to learn. The classroom needs to be a space where students feel connected with one another, and with what they’re learning. Instructor training will prioritize this.
How is the center reimagining teaching and learning now that AI is increasingly impacting education?
Bok’s Learning Lab is focused on harnessing AI to design groundbreaking tools that personalize and enhance learning experiences and also foster critical understanding of AI’s broader implications. Our workshops and faculty collaborations don’t just react to technological trends; they’re aimed at anticipating and shaping the future, equipping our educators and students to thrive in an AI-augmented academic environment. We know some faculty want to learn more, but don’t know where to start. My aim is to equip a much broader range of faculty to teach in the age of AI. For some faculty members, this will involve partnering with the Bok Center to develop ways of harnessing AI to augment the teaching and learning process. For others, this might involve working with the center on how to encourage their students to think critically about the ethics of AI or how to give even greater emphasis to the in-person, experiential learning that is possible only in brick-and-mortar classrooms on a residential campus like Harvard’s. Ultimately, the faculty determine the learning objectives that matter in their classrooms, and the Bok Center stands ready to help them achieve the outcomes they desire.
Nation & World
How progress happens
Vice provost for research details crucial role of NIH support in science and medicine
Alvin Powell
Harvard Staff Writer
February 13, 2025
long read
On Feb. 7, the National Institutes of Health issued a notice, effective Feb. 10, to cap reimbursements for indirect costs (IDC) associated with its grants. The world’s largest public funder of biomedica
Vice provost for research details crucial role of NIH support in science and medicine
Alvin Powell
Harvard Staff Writer
long read
On Feb. 7, the National Institutes of Health issued a notice, effective Feb. 10, to cap reimbursements for indirect costs (IDC) associated with its grants. The world’s largest public funder of biomedical research, the NIH supports investigations into, among other things, efforts to fight cancer, control infectious disease, understand neurodegenerative disorders, and improve mental health. The agency is a significant sponsor of research at Harvard, with more than 1,500 active grants and $488 million in funding this past year; the new cap would result in a loss of more than $100 million annually for the University.
The move prompted multiple lawsuits to halt implementation of the change: one brought by the attorneys general of 22 states, including Massachusetts; one led by the American Association of Medical Colleges (AAMC); and a third led by the American Association of Universities (AAU), to which Harvard submitted a declaration of support. On Monday, a federal judge granted temporary restraining orders stopping NIH from taking steps to implement or enforce the change pending further orders from the court.
The Gazette discussed indirect costs with John H. Shaw, Harvard’s vice provost for research, who has kept the University community informed on recent changes and filed a declaration outlining Harvard’s position in the AAU case. This interview has been edited for clarity and length.
John H. Shaw, Harvard’s vice provost for research.
What are indirect versus direct costs?
Direct costs are costs related to the conduct of the work itself: in some cases, including salaries for those engaged in the project, equipment, travel expenses, and things of that nature. But when you think about the true cost of that work, other things also need to be considered: the building, the infrastructure, the labs that our researchers work in, electricity and utilities that support the building, and administrative staff that enables that research and ensures we are compliant with the terms and conditions associated with that research activity.
It is important to emphasize that all of those indirect activities are necessary to support the research activities. Reimbursements for indirect costs from sponsors such as the NIH don’t go into a slush fund for an institution to use as it sees fit. We have an obligation to the sponsor to ensure that those monies are spent to support the research.
So, though these costs are indirect, it’s not accurate to think of them as “incidental”?
No — they’re integral to the research. We need buildings; we need labs; we need computer resources; we need the networks to enable scholarship across so many fields and disciplines. Without the resources provided through reimbursement of indirect costs, the work essentially can’t proceed.
Over the last 20 years, there have been huge changes in how biomedical science is conducted. Have those changes affected indirect costs?
The innovation coming out of our labs is directly related to advances in technology over the last several decades. Consequently, the cost of research has increased across the board. For example, labs have become more sophisticated and imaging technologies have become more advanced. Equipment — much of it field-specific and highly specialized — has become more complex. And the costs of building and maintaining those lab facilities and specialized equipment, of providing the computers that power rigorous and novel analyses, have also increased.
Our strategy is to provide the resources needed for a particular lab through a sponsored research agreement or a University contribution. When something is needed by more than one investigator, we scale that resource and support it in a way that enables its use across the institution. This is the benefit of conducting research at a university level.
What is Harvard’s indirect cost rate?
The indirect rate varies somewhat across our Schools, but for the general University, the rate is 69 percent. That rate, considered in the context of other modifiers — such as subtracting elements like equipment expenses — determines the indirect costs that are reimbursed by the sponsor to support the research.
People often quote the 69 percent number. One point of clarification: This does not mean that 69 percent of the total funding goes toward indirect costs. It means that 69 percent of modified direct funding gets added on top to help defray some of the support costs. In the end, if you look at this all holistically, about 30 percent of the money we receive from the federal government for sponsored research goes toward indirect costs. The remaining 70 percent is used directly for the research activity.
The indirect funds we receive from a sponsor never cover the full cost of all the infrastructure and activity that are necessary to support research. The research partnership, between a university and a research sponsor, means that both of us contribute.
“However you do the accounting, less money invested in research and scholarship means fewer people engaged in research. It means less innovation and fewer discoveries from academic research labs that benefit the American people.”
In the NIH’s announcement, they cited lower numbers for other institutions. Why is Harvard’s rate higher?
Indirect rates across various sponsors, particularly between the federal government and foundations, are not directly comparable. They include and exclude different components to which the rate is applied.
Our indirect calculation is negotiated periodically between Harvard and the federal government. We calculate ours with the Department of Health and Human Services because of the degree of life science research in which we engage. The indirect rate calculation includes two components: an administration component and a facilities component.
The administration component encompasses, basically, the staff and systems needed to manage the project financially and ensure compliance with federal regulations and requirements. There’s a view that rising costs are due to administrative bloat — that the number of administrators is driving this up. But that’s not the case. The rate we receive for administration has been capped for more than two decades, and we spend more than we receive on indirect costs to ensure that these projects are properly supported.
The facilities component looks at our buildings, our labs, and the cost of maintaining and operating them, and that’s where variation between institutions happens. The portion of those facilities that is used for research is factored into this rate. That’s why different institutions in different parts of the country, with different real estate markets and scales and complexity of laboratory activities and other facilities, have different indirect rates.
You mentioned computing infrastructure as part of the growing expense of conducting research. Does the University provide computing resources centrally, or is it allocated to different grants?
Computing involves different components of support, some general and some research-specific. The general components tend to be covered within the IDC calculation. Those are items like the networks, basic data storage — things of that nature. Things that are project-specific — and often larger-scale — are typically included in direct charges. A good example is supercomputing resources. If you need access to a large GPU or CPU cluster to enable your science, there’s a rate you pay to whichever part of the University is supporting that cluster to give you access to that computer.
Another area where this is very important is in regulated data. These are data sets necessary for research that need to be kept private and secure, such as identifiable healthcare data. We have set up specialized systems and, over the last two years, have developed a University-regulated data environment that serves faculty across the institution. That’s an additional expense, dedicated to a specific type of research activity, and so faculty use would typically be included in the direct charges for a grant. So, there’s not one answer for computation. It really depends on the scale and the specific tie to the research activity.
So, since even just 10 years ago, we’re in a different environment with regard to dependence on big data, enormous computing power, and the associated costs?
Absolutely. I would add that we’re also facing an increasingly complex federal regulatory landscape. We need to ensure that the information and the findings supported by the federal government are secure. That means putting in place protections so that bad actors can’t access that data, which would not just undermine the contributions of our researchers, but also not be in the nation’s interests. So, this high-level computer capacity and the security systems that we put in place are both important national priorities — priorities that we share as an institution.
As vice provost for research, you filed a declaration in support of the AAU lawsuit. You estimated the cost of this change to Harvard as more than $100 million on an annualized basis for FY25, and $590 million through 2030. Can Harvard absorb these costs?
There would be pain associated with these changes. As a nonprofit, we reinvest our resources every year to advance our fundamental mission of teaching and research. To put these figures in context, the $100 million annualized cost is more than double the University’s operating surplus last year. So, despite having a significant endowment, we don’t have surplus resources readily available to meet that kind of shortfall.
Why can’t we use the endowment?
There’s a misconception that Harvard’s endowment can be used as a checking account. In reality, the endowment is made up of thousands of individual funds that are committed to specific purposes based on the legal terms of the donor’s gift. These philanthropic gifts are critical to supporting the University’s mission, including our commitment to student financial aid. Harvard distributes as much as it responsibly can from the endowment to serve current and future generations of students and scholars in advancing knowledge; to be clear, we do invest significant resources to support research beyond what we get from the IDC reimbursement. We strive to conduct all of this research at the highest level, and the investments we make signal our commitment to this goal. So, these changes would have a material impact on our ability to advance that research.
Another thing to recognize is that the NIH policy change does not mean that federal dollars will be redirected to support research in other ways — for example, through an increase in direct budgets. There will be less money invested in science. However you do the accounting, less money invested in research and scholarship means fewer people engaged in research. It means less innovation and fewer discoveries from academic research labs that benefit the American people.
What are recent examples of Harvard’s research benefitting the public?
There are many, such as gene therapies for disease — using novel gene-editing technologies as treatments for sickle cell anemia and other conditions. There are cellular and genetic therapies for treating certain types of cancer. There are investigations into understanding and mitigating the spread of infectious and drug-resistant disease. All those things have their foundation in academic research and would be impacted by this lower level of investment.
You mentioned in your filing a 75-year partnership between the federal government and research universities. How has this partnership worked?
It’s a partnership that is the envy of the world — one that’s driven scientific progress, economic growth, and American leadership in innovation and discovery.
The relationship is built around the recognition of the importance of fundamental research in driving scientific discovery. Fundamental research carries risk, because you often don’t know how it’s going to turn out and the path ahead is unclear. Academic institutions are well-suited to engage in true curiosity-driven discovery and innovation — more so than for-profit companies, which think on a shorter timeline and focus on how to develop research into things that will be profitable. This is the essence of the partnership: The government gets the most bang for its buck by partnering with institutions of higher learning and finding ways, as advances emerge, to translate them into positive economic and societal impacts in areas like healthcare.
You mentioned the economy. How significant are the economic benefits of research?
There’s a clear payoff, though its magnitude depends on who does the assessment. In Massachusetts, for example, every dollar of sponsored research invested by the federal government yields two to three times that benefit in its economic value to the region. It’s a win for both sides and serves as an economic engine for the state and the nation.
To take an example outside of the life sciences: Harvard is at the vanguard of quantum science, where there have been active scientific investigations for decades that were always viewed as fundamental and far from providing any benefit. But we’re now building quantum computers in the Massachusetts Green High Performance Computing Center. We have faculty members who are leaders in this space, who are developing new startup companies to ensure this transformation will have real, measurable economic impact across the state and the region. Federal funding has played a key role in quantum science research since its beginnings.
We’re rich with examples of fundamental research that takes time to percolate, whose ultimate impact is not known at the outset. That means it’s not a good idea to narrow your bets early on. Instead, you need to support broad scholarship and research and train the next generation of talent who, in some cases, are going to be the ones who take what you have learned and enable its impact.
How important is stability to the research? You make the point that research builds on what came before, and that disrupting research today slows things in the long run.
Disruption can hurt in a couple of different ways. For active research projects that involve cellular lines or animal research, you can’t simply stop without losing something significant. A pause means taking steps backward.
More importantly, though, this is about human beings. It’s about talent. It’s about the ability of people to learn and grow, to become more capable, to develop insight. In many ways, we are the world’s beacon for that process, that dream. People from across the world come to participate in that research mission. Turning off that pathway will have drastic long-term effects on the quality of the research that we engage in and, ultimately, on its impact on society.
Photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
Traffic death hot spots? Hidden chronic illness?
Sy Boles
Harvard Staff Writer
February 13, 2025
1 min read
How closely did you follow the Gazette this week? Take our quiz to find out.
A deep dive into the Department of Education. A change to what drives inequality in prison admissions in the U.S. What do you remem
How closely did you follow the Gazette this week? Take our quiz to find out.
A deep dive into the Department of Education. A change to what drives inequality in prison admissions in the U.S. What do you remember from this week in the Gazette?
Campus & Community
Legacy of Slavery expands work with oldest genealogical nonprofit in U.S.
Memorial Hall. Photo by Grace DuVal
Andrea Perera
Harvard Correspondent
February 13, 2025
long read
Partnership laying groundwork for University to engage with direct descendants
Harvard has expanded its partnership with American Ancestors, with the nation’s oldest genealogical nonprofit lea
Legacy of Slavery expands work with oldest genealogical nonprofit in U.S.
Memorial Hall.
Photo by Grace DuVal
Andrea Perera
Harvard Correspondent
long read
Partnership laying groundwork for University to engage with direct descendants
Harvard has expanded its partnership with American Ancestors, with the nation’s oldest genealogical nonprofit leading efforts to advance descendant research in the Harvard & the Legacy of Slavery Initiative. The University began the collaboration in 2022 upon the creation of the initiative, which was established to implement the recommendations of the Presidential Committee on Harvard & the Legacy of Slavery.
“American Ancestors is recognized globally for the thoughtfulness and rigor of its research efforts,” said Harvard University President Alan M. Garber in a Jan. 23 announcement. “We look forward to the expertise and skill with which [they] will continue to build on the foundation we laid in 2022.”
The initiative established the Harvard Slavery Remembrance Program, which includes the work being led by American Ancestors to research the individuals enslaved by Harvard leaders, faculty, and staff, and their descendants.
“Slavery was such a dark moment in our nation’s history, and through this research, we have an opportunity to bring light and greater understanding of its legacy for today,” said Evelynn Hammonds, a member of the initiative’s advisory council and the Barbara Gutmann Rosenkrantz Professor of the History of Science and professor of African and African American Studies, and professor in the Department of Social and Behavioral Sciences, T.H. Chan School of Public Health.
The Slavery Remembrance Program is one of several priorities the initiative is pursuing as the University moves into the next phase of the work to implement the Presidential Committee recommendations.
“In addition to unearthing the sad facts of the history of slavery in our University’s history, this research is reconstructing family histories that in most cases have been lost for generations.”
Annette Gordon-Reed
“In addition to unearthing the sad facts of the history of slavery — both directly and indirectly — in our University’s history, this research is reconstructing family histories that in most cases have been lost for generations,” said Annette Gordon-Reed, also a member of the advisory council and the Carl M. Loeb University Professor.
Members of the advisory council, such as Henry Louis Gates Jr., director of the Hutchins Center for African and African American Studies, and the Alphonse Fletcher University Professor, are guiding the work of the initiative across its priorities, including the descendant research.
Gates, who also serves as an honorary trustee of American Ancestors and a member of the advisory board for its 10 Million Names project, noted the ability of American Ancestors to tackle the enormity and complexity of researching the family histories of enslaved people — and the value that comes from the research.
“American Ancestors has been the gold standard in genealogical research for more than 100 years and has been a vital research partner to Harvard since 2022. In fact, its researchers are responsible for recovering virtually all the descendants of people enslaved by Harvard officials collected in our database thus far,” Gates said. “The results of their continued research, as interpreted by the advisory council, will be foundational to the engagement the University will have with living direct descendants.”
The Gazette recently sat down with Sara Bleich, vice provost for special projects and leader of the Harvard & the Legacy of Slavery Initiative; Ryan J. Woods, president and CEO of American Ancestors; and Lindsay Fulton, chief researcher at American Ancestors, to learn more about the partnership and what this next phase of work looks like.
Sara Bleich.
Stephanie Mitchell/Harvard Staff Photographer
Sara, what kind of research is American Ancestors doing in partnership with Harvard?
When Harvard released the Harvard & the Legacy of Slavery report in 2022, one of the commitments the University made was to identify the direct descendants of those who were enslaved by Harvard leaders, faculty, or staff. It was clear that the 79 enslaved people identified at the time of the report’s release represented only a fraction of those likely enslaved.
Since 2022, American Ancestors has been working on behalf of Harvard to identify additional enslaved individuals and their direct descendants. They will now build on and significantly increase their efforts as part of our expanded partnership.
How does this research fit into the Harvard & the Legacy of Slavery Initiative’s near-term priorities?
Early in the fall semester, we worked with our advisory council to think about our focus as we build on the foundation laid over the last 2½ years. That process reaffirmed three priority areas.
One is memorialization and education, which includes the University’s commitment to create a campus memorial to those whose labor contributed to the growth of Harvard. Our education efforts include continuing to build on initiatives like the creation of new courses, the campus walking tour, and lots of efforts to educate the Harvard community and beyond about Harvard’s complicity in slavery.
The third area is supporting descendant communities; this includes the reparative grant program, which aims to address systemic inequities in Boston and Cambridge and in regional tribal communities, and continuing the direct descendant research. On this last point, we are excited about the expanded partnership with American Ancestors to help us advance and scale descendant research.
Ryan J. Woods.
Claire Vail Photography/American Ancestors
Ryan, can you describe the work that American Ancestors does?
American Ancestors was founded in 1845 as the New England Historic Genealogical Society. We are a not-for-profit national center dedicated to the study of family history, heritage, and culture. We employ a staff of just over 100 individuals who are historians, genealogists, educators, archivists, librarians, and data specialists who help to support our more than 400,000 members and subscribers research their family history.
We do this work in any number of ways, including digitizing records, doing archival research, and publishing new information in the field of genealogy.
In 1870, we established something known as “register style.” It is one of the most widely used and accepted formats for presenting genealogical research in a scholarly fashion. That begins with identifying a person in the past and then researching and presenting their descendants down toward the present.
“What we have done in this work is start in the past, prior to 1870, and then we can identify and establish that person and begin to trace their descendants, essentially knocking down the brick wall from behind.”
Ryan J. Woods
Where does the Harvard research stand right now?
To date, the Harvard Slavery Remembrance Program has identified at least 229 Harvard leaders, faculty, and staff who enslaved individuals in the 17th, 18th, and 19th centuries.
Through HSRP-related research we’ve conducted here at American Ancestors, we’ve found thus far that those identified Harvard-associated individuals enslaved as many as 940 people who had as many as 1,211 descendants, who are now deceased, and at least 460 living descendants.
We update these numbers monthly and expect that the numbers will continue to grow as research progresses.
The mathematics of population demographics are such that, as research progresses, the numbers will grow exponentially. If you start with yourself, for example, you have two parents, four grandparents, eight great-grandparents, sixteen great-great-grandparents, and so on, by the time you go back 10 generations, you have 512 10th-great-grandparents.
Looked at from the opposite direction, the past toward the present, if you took somebody, say, born in 1750, they are likely nine to 10 generations beyond someone living today. A person born in 1750, mathematically, will have around 262,000 total descendants, living and deceased. So, as you can see, this research will likely result in a large number of people found.
Lindsay Fulton.
Claire Vail Photography/American Ancestors
Lindsay, how do you do this genealogical research? Does the approach differ depending on the population you are researching?
When people of European descent do work like this to discover their ancestry, they tend to start with themselves and then work back into the past, and they use record sets like vital records and church records. It’s about a specific person. That record was made for them, and then we work back in time.
When we look at enslaved people, you’re basically doubling the research because you have to research the enslavers and the people they enslaved. You research the enslavers and then the record sets created to account for an estate and its objects. We find enslaved individuals mentioned on inventory lists or an enslaver might die and then they leave a probate. That may include the number of acres that they owned, those they enslaved, cows, spoons, and forks. And those are the types of records that we need to use to extend this work back into the past.
Sometimes there might be a collection that is held not at a government entity, but maybe by a public institution. An enslaver or their descendant may have donated their estate records — journals, diaries, etc., to a university or a smaller historical society.
In those cases, we find a treasure trove of information about enslaved people. If an enslaved person had a child, for example, that might be recorded by the enslaver in a journal or diary. I know of an instance where there was a plantation that was reissuing shoes to everyone on the plantation. There was a list of the names of all those individuals and their shoe sizes in a particular year, and that’s why we know who was living there at a particular moment in time.
Those family records can be incredibly helpful, but they are not as easy to find as a census record, tax list, or even probate, for that matter.
Woods: This research can be particularly difficult for someone with enslaved ancestors because you begin to run up against what we refer to in the field as the “brick wall of 1870.” Eighteen-seventy is the first federal census after Emancipation that includes the full names of previously enslaved people.
You can likely get back to 1870, but going further back in the past becomes increasingly more difficult when you start with the present, research back, and then hit that wall.
What we have done in this work is start in the past, prior to 1870, and then we can identify and establish that person and begin to trace their descendants, essentially knocking down the brick wall from behind.
Sara, why does this research matter?
The plain truth is that Harvard leaders, faculty, and staff enslaved individuals. Part of our effort to address this harm is to give individuals their histories back, which is largely unknowable unless you know where to look.
American Ancestors knows how to do this research. They have deep experience in African American genealogy, they know that it’s going to take time, and that you have to look in unusual places.
Through this work, we want to give the gift of history and name people. This is a really important step, and it is something we take very seriously. The University is committed to doing this work and that is why we have engaged the best-in-class partner to do it with us.
Ryan, American Ancestors does this work with all kinds of different organizations. What’s it like when you’re able to give people their family histories?
Engaging in family history enriches lives. It’s a source of joy, education, inspiration, empowerment, and it’s also a means of healing and repair. Decades of research have shown the positive social and emotional benefits of knowing one’s family history. The literature on this is correlated to positive effects on young people, in particular.
There are also studies that look at how engaging in family history has positive effects on adult populations. This has shown that there are social and emotional benefits in family units and that the act of engaging in family history can develop and strengthen cognitive skills.
Sara, how are you beginning to think about engaging with direct descendants in the future?
We have to approach even the initial engagement with direct descendants with the utmost sensitivity. For many, they will be learning about their connection to Harvard’s Legacy of Slavery for the first time through our outreach.
Before we even begin taking further steps, we need to ask what’s most important to them. In our report, the University already expressed an interest in several kinds of activities, such as engaging in dialogue, programming, information sharing, relationship building, and providing educational support.
The other thing that we will do — because we’re not the first to think about engagement with direct descendants — is to look to our partners and other universities and institutions to understand what they did. What worked well? What didn’t work? What can we learn? What can we do differently and better?
There are many possibilities, but most importantly, we must approach this engagement with empathy, humility, grace.
Arts & Culture
Tech has changed. Dating? It’s complicated.
Illustration by Liz Zonarich/Harvard Staff
Eileen O’Grady
Harvard Staff Writer
February 13, 2025
8 min read
If you think algorithms and chatbots are ruining romance, ‘Labor of Love’ author has a history lesson for you
Moira Weigel began researching the history of dating in the early 2010s during a pivotal cultural moment in t
If you think algorithms and chatbots are ruining romance, ‘Labor of Love’ author has a history lesson for you
Moira Weigel began researching the history of dating in the early 2010s during a pivotal cultural moment in the U.S. The effects of the Great Recession were still deeply felt, mobile phone apps were taking off, and the internet buzzed with think pieces dissecting the state of modern romance.
“There was this whole discourse about how the recession was impacting men and women differently, undermining so-called traditional gender roles,” said Weigel, assistant professor of comparative literature. “At the same time, there was a lot of conversation about the impact of social media on romantic relationships. The intersection of those topics made me interested in this subject.”
The result was her first book, “Labor of Love: The Invention of Dating” (2016), which sought to challenge some pessimistic ideas that match apps were bringing about the “end of dating” or changing it beyond recognition. Instead, she argued, courtship had evolved with women’s entry into paid work and with consumer capitalism.
Weigel, who joined Harvard’s faculty in 2024, is teaching “Media, Technology & Social Change” and “Global Media” in the Department of Comparative Literature. While her current research focuses on data-driven technologies such as social media and marketplace platforms, and new developments in AI and machine translation, she remains fascinated by trends in tech and courtship.
In this edited conversation with the Gazette, Weigel discusses how dating has evolved over the years and the surprising historical precedent for chatbot girlfriends. (Spoiler alert: Dating anxiety is not just a modern struggle.)
Today, many dating apps boast highly personalized algorithms aimed at narrowing search parameters. What are the implications of such a high degree of personalization?
There is a promise that comes with these apps, particularly as their user base has gotten larger and algorithms more sophisticated and dynamic, that they are going to make courtship more efficient. Apps promise to provide a larger selection of possible partners than, say, your local bar, and to sort them into personalized results. The technical logic is not unlike that of online marketplaces.
But dating apps did not invent this. I always like to push back against thinking about these questions too techno-deterministically, as if technology alone makes culture change. In my research for “Labor of Love,” I looked at video dating libraries from the 1980s, where people would record VHS tapes of themselves and file them in a collection where members could go search according to different traits. People have placed personal ads in newspapers for centuries. The earliest versions of Match.com or OKCupid mostly used elaborate multiple-choice questionnaires to sort people. Now most of the famous dating apps use dynamic forms of machine learning to consider different data points and adapt based on user behavior. Desires for scale, efficiency, and personalization are older than algorithms.
Stephanie Mitchell/Harvard Staff Photographer
How has technology shaped how people date and find love?
The history of love and the history of technology have always been intertwined: We could talk about the automobile, or the telephone, or the steam engine as technologies that changed courtship. But among contemporary, data-driven technologies I think one very important change came with the normalization of mobile phone apps. These had this really interesting effect of blending the online and offline. When you look back at so-called “cyber-dating” in 1990s shortly after the World Wide Web was popularized, many people expressed this sense that the internet was another world that you went into through your desktop computer. A lot of the moral panic about people looking for sexual or romantic connections online revolved around the idea that such connections were “unreal” and would disconnect you from relationships that were supposed to be more appropriate and meaningful. Mobile phones and social apps have now totally eroded the boundary between online and offline. Dating has become something you can engage in on your phone, between responding to a work email and ordering a taxi or a burrito. That produced a bunch of different changes which are hard to disentangle.
What were some of those changes?
I think it removed a lot of the stigma that had been attached to online dating or older practices like video dating. I think it “re-rationalized” courtship, making people more comfortable with the idea that finding a partner was not entirely a matter of spontaneity, instincts, and effortlessness, that there might be some social scripts and search parameters involved.
Throughout history, has finding a partner been more about romantic spontaneity or a rational search process?
In the scope of human history, the idea of choosing partners based on chance encounters and their own personalities or sensibilities is a very new one. It emerged in the West, in 18th- and 19th-century Europe and the U.S., alongside political and industrial revolutions that produced new ideals about individuality, society, and freedom.
Before industrialization, if you worked on a farm with your extended family, it was rational to marry the guy who lived on one of the next farms and merge your property and labor. Besides, where else were you going to meet someone? Economic and technological changes changed the meaning and function of love and marriage. It’s no accident that so many of the great 19th-century novels were about the difficulty of making personal attractions and emotions the basis of marriage. Think of “Elective Affinities” (Johann Wolfgang von Goethe), “Madame Bovary” (Gustave Flaubert), or “Anna Karenina” (Leo Tolstoy).
Over time, there emerged an ideal of attraction and love as “anti-practical,” because it’s supposed to be an expression of freedom, excitement, and possibilities of modern life. Charles Baudelaire’s “À une passante” (“To a Passerby”), about walking past a stranger on the street, captures the idea that you might see anyone in a city, that anyone might be the love of your life, or you might never see them again. These ideals cast romance as the opposite of calculating.
Algorithms literally calculate, and dating apps use algorithms to optimize for certain kinds of partners. To me, that’s where dating apps bring in explicit rationalization that feels different from the dominant romantic ideals of the past century or two.
“The history of love and the history of technology have always been intertwined.”
Stephanie Mitchell/Harvard Staff Photographer
How are technologies like generative AI and chatbots impacting how people date?
What I have seen around dating apps mirrors what you see in all sectors of the digital world or the economy. I’ve anecdotally heard about people using chatbots to generate lots of messages to people or using AI to sort such messages. For years there has been this trend toward virtual dating assistants, who would look through people for you, like matchmakers, and it makes sense that folks might use GPTs to do some of that.
The other thing that people talk about is chatbot girlfriends and boyfriends. That, of course, has a very old cultural history.
Could you say more about that?
There have been so many different literary representations of this fantasy of creating your perfect partner — a dream come true that also usually turns out to be a kind of nightmare. We could look at the Greek and Latin myth of Pygmalion. We could look at so many narratives of automata in 19th-century Europe, from E.T.A. Hoffmann’s “The Sandman” to Auguste Villiers de l’Isle-Adam’s “The Future Eve.” To go way back, we could talk about Eve being made from Adam’s rib to be his helpmate. The depth of that trope of a human (usually a man) building the ideal partner is fascinating to me. It comes up in movies, too: classic films like Fritz Lang’s “Metropolis” (1927) or Ridley Scott’s “Blade Runner” (1982) or more recent ones like “Her” (2013) and “Ex Machina” (2014) or that HBO show “Westworld.” All these stories explore what humans want in one another, but also how we project our desires onto machines and other arts. We can develop deep attachments and emotions to made objects, but there’s always an undercurrent of danger and loss that comes with that kind of mastery. So even though something like Replika, the chatbot girlfriend, does not perhaps seem like an intellectually sophisticated thing, it ties into this deep history.
What about for people who are frustrated with the culture of modern app dating? Is there historical precedent for this?
A sense of crisis lies deep in the DNA of dating. There are no moments in the history that I researched where people were saying, “It’s great! It’s fine! I’m not worried about it!” At every moment there’s an anxiety about dating, which also becomes the occasion for a lot of cultural production, too: self-help books, romantic comedies, YA novels, not to mention all the things companies sell people to try to help them feel more desirable. That sense of anxiety is really culturally and economically productive. And so, even as it changes, it seems to find a way to carry on.
Campus & Community
Ballot finalized for Overseer and HAA director elections
John Harvard Statue covered in a fresh layer of snow.Photo by Grace DuVal
February 13, 2025
5 min read
Candidates listed in official ballot order
Eligible Harvard alumni will once again have the chance to participate in the elections for new members of the Harvard Board of Overseers and the elected directors of the Harvard
Ballot finalized for Overseer and HAA director elections
John Harvard Statue covered in a fresh layer of snow.
Photo by Grace DuVal
5 min read
Candidates listed in official ballot order
Eligible Harvard alumni will once again have the chance to participate in the elections for new members of the Harvard Board of Overseers and the elected directors of the Harvard Alumni Association this spring.
Voting begins on April 1, with completed ballots being accepted until 5 p.m. on May 20. Alumni can cast their votes either online or via paper ballot for five expected vacancies on the Board of Overseers and six available positions among the HAA elected directors.
Eligible voters include all Harvard degree holders as of Jan. 1, with the exception of Harvard’s officers of instruction and government, as well as members of the Harvard Corporation, for the Overseer positions. For the HAA elected directors, all degree holders as of Jan. 1 are welcome to vote.
The candidates listed below have been named by the nominating committee appointed by the Harvard Alumni Association’s volunteer leadership. The candidates’ names appear below in ballot order, as determined by lot.
Overseer candidates
Michael Rosenblatt M.D. ’73, magna cum laude B.A. ’69, summa cum laude, Columbia University Newton, Massachusetts
Anjali Sud M.B.A. ’11 B.S. ’05, University of Pennsylvania New York
Lanhee J. Chen A.B. ’99, magna cum laude, A.M. ’04, J.D. ’07, cum laude, Ph.D. ’09 Mountain View, California
Mark A. Edwards A.B. ’82, cum laude Brookline, Massachusetts
Mary Louise Kelly A.B. ’93, magna cum laude M.Phil. ’95, University of Cambridge, with distinction Washington, D.C.
Nathaniel Owen Keohane Ph.D. ’01 B.A. ’93, Yale University, magna cum laude New York
Courtney B. Vance A.B. ’82 M.F.A. ’86, Yale University La Cañada Flintridge, California
A previously announced candidate, Valerie Montgomery Rice, M.D. ’87, president and CEO of Morehouse School of Medicine and an alumna of Georgia Institute of Technology (B.S. ’83), has decided to withdraw her candidacy for the Board of Overseers. “Harvard holds a special place in my heart, and while I am honored by the nomination, my current responsibilities demand my full attention,” said Montgomery Rice. “I am grateful for the support and remain committed to Harvard’s mission in other ways.”
HAA elected director candidates
Angela M. Ruggiero A.B. ’02, cum laude, M.B.A. ’14 M.Ed. ’10, University of Minnesota Weston, Massachusetts
Allison Lee Pillinger Choi A.B. ’06 Bedford, New York
Sanjay Seth M.P.A. ’19, M.U.P. ’19 B.A. ’12, Goldsmiths, University of London East Boston, Massachusetts
Nicholas J. Melvoin A.B. ’08 M.A. ’10, Loyola Marymount University; J.D. ’14, New York University Los Angeles
Theresa J. Chung A.B. ’98, magna cum laude, J.D. ’02 Dallas, Texas
Daniel H. Ahn A.B. ’90, magna cum laude, M.B.A. ’97 Burlingame, California
Colin J. Kegler A.B. ’97 Provincetown, Massachusetts
Victoria “Vicky” Wai Ka Leung A.B. ’91, cum laude M.B.A. ’98, New York University London
Pavlos P. Photiades A.B. ’88, magna cum laude Nicosia, Cyprus
The nominating committee brings together 13 alumni with varied backgrounds and includes three current or recent Overseers who have direct experience with the workings and needs of the board. The committee invites and receives suggestions about possible candidates from across the alumni community and reviews information on hundreds of prospective candidates as part of extensive deliberations throughout the fall term.
The committee seeks to develop a set of Overseer candidates that takes account of the board’s present composition and the University’s future needs. The committee considers experience and accomplishment in an academic or professional domain important to the University; interest in and concern for higher education and for Harvard University as a whole; commitment to the overall quality and continual improvement of Harvard’s programs of education and research; willingness to invest the time and energy necessary for effective service; understanding of complex organizations, and leadership and consensus-building skills.
The Board of Overseers is one of Harvard’s two governing boards, along with the President and Fellows, also known as the Corporation. Formally established in 1642, the board plays an integral role in the governance of the University, complementing the Corporation’s work as Harvard’s principal fiduciary board. As a central part of its work, the board directs the visitation process, the primary means for periodic external assessment of Harvard’s Schools and departments. Through its array of standing committees, and the roughly 50 visiting committees that report to them, the board probes the quality of Harvard’s programs and assures that the University remains true to its charter as a place of learning. More generally, drawing on its members’ diverse experience and expertise, the board provides counsel to the University’s leadership on priorities, plans, and strategic initiatives. The board also has the power of consent to certain actions, such as the election of Corporation members. The current membership of the board is listed here.
The HAA board, including its elected directors, is an advisory board that aims to foster a sense of community, engagement, and University citizenship among Harvard alumni around the world. The work focuses on developing volunteer leadership and increasing and deepening alumni engagement through an array of programs that support alumni communities worldwide. In recent years, the board’s priorities have included strengthening outreach to recent graduates and graduate school alumni and continuing to build and promote inclusive communities.
Ann Marie Lipinski.Photo by Lisa Abitbol
Campus & Community
Nieman curator Ann Marie Lipinski to step down
Pulitzer winner steered foundation through a period of disruption for the news industry and deepened collaboration with the Harvard community
February 13, 2025
8 min read
Ann Marie Lipinski, the curator of the Nieman Foundation for Journalism at Harvard University, will step down on July 1, comp
“Ann Marie and I returned to Harvard at the same time — our appointments announced just days apart — and I have watched with admiration as she has met change after change with energy and optimism, always centering her efforts on recruiting and nurturing outstanding fellows,” said Harvard President Alan Garber. “Her influence on countless careers and her impact on the field itself will continue to shape how news is produced and consumed around the world. I cannot imagine a leader better suited to have led the Nieman Foundation through a period of profound transformation for journalism.”
“I am grateful to Ann Marie for her leadership over the past 14 years,” said Provost John Manning. “Her dedication to the foundation, to innovative journalistic practices, and to engagement with the larger Harvard community has been invaluable to both the Nieman Foundation and the University.”
A Pulitzer Prize-winning journalist and former editor in chief of the Chicago Tribune, Lipinski was appointed Nieman curator in 2011, the first woman to lead the program.
“It has been a profound privilege to lead Nieman, not in spite of the industry complexities but because of them,” Lipinski said. “Each year, journalism faced new challenges and each year, a new class of fellows rose to confront them. Fortifying those journalists for the future is essential. I am grateful to the colleagues who joined me in that work, strengthened collaboration here on campus, and supported a global community sometimes fighting for the very right to practice journalism.
“It has been a profound privilege to lead Nieman, not in spite of the industry complexities but because of them.”
Ann Marie Lipinski
“I have found both purpose and joy as Nieman’s curator and am deeply grateful for the trust that Harvard has placed in me. I believe it is now time for others to lead this work that I have loved.”
A 1989-1990 Nieman Fellow, Lipinski as curator guided the foundation through years of unprecedented disruption, including the pivot from print to digital; the proliferation of dis- and misinformation; growing reliance on artificial intelligence to report the news; the ascendance of social media; and the shuttering of hundreds of local news outlets. She also worked to bring attention to assaults on journalists, including the killing of two Nieman alumni on assignment (Associated Press photographer Anja Niedringhaus and documentary filmmaker Brent Renaud), and the imprisonment of others.
Nieman’s record of innovation
Lipinski recalibrated the fellowship to include more journalists from emerging news organizations. She collaborated with Harvard’s Berkman Klein Center for Internet & Society to launch the Nieman-Berkman Fellowship in Journalism Innovation; supported local reporters with a two-year fellowship for local investigative journalists; and bolstered writing on China by offering a specialized two-year fellowship in partnership with the AP.
In her first year as curator, she introduced the Nieman Visiting Fellowship, offering short-term research opportunities not only to journalists, but also technologists, publishers, and academics working to advance journalism. And she recommitted to Nieman’s support of journalists, some in exile, who have labored in countries where independent reporting is treated as a crime.
Lipinski focused Nieman’s publications on exploring journalism’s greatest threats and opportunities. Last year, she added writers to Nieman Lab, a widely read digital report on the future of news, to cover the rise of generative AI and the dramatic upheaval on the country’s local news landscape. Through the Nieman Storyboard website and translations of the foundation’s popular “Telling True Stories” guide for nonfiction storytelling, Nieman extended its support for narrative journalism.
Lipinski additionally led a redesign and digital expansion of Nieman Reports and directed numerous cover stories, from “Where Are the Women?,” about the dearth of female leadership in newsrooms, to the current “Dear America” issue, a collection of dispatches to the U.S. media from journalists working in countries where press freedom is under attack.
“International journalists are hearing echoes,” Lipinski wrote in that issue. “From countries around the world that have witnessed the rise of autocratic and populist leaders, they are watching the U.S. and warning of a characteristic of wounded democracies everywhere: an endangered free press.”
Commenting on Lipinski’s departure, Nieman Advisory Board chair John Harwood said: “There’s no better tribute to Ann Marie Lipinski’s leadership than recognizing that, as journalism faces mortal economic and political threats, she has made the Nieman Foundation stronger. Her foresight, creativity, and integrity have enriched not just 14 classes of fellows but our entire profession.”
Campus and public engagement
Lipinski committed to serving journalists beyond the fellowship and initiated a series of intensive workshops for reporters and editors covering immigration, climate change, housing, and nuclear issues. The conferences were planned in collaboration with Harvard faculty and researchers from across the University.
Nieman worked with the University of Chicago Institute of Politics to train political journalists on reporting beyond the horse race in the run-up to the 2016, 2020, and 2024 U.S. presidential elections. Lipinski also advanced Nieman’s efforts to mentor a new generation, expanding the Christopher J. Georges Conference on College Journalism, planned annually in partnership with The Harvard Crimson, to include public colleges and HBCUs far beyond the East Coast schools from which the conference had traditionally drawn attendees.
During Lipinski’s curatorship, Nieman brought leading thinkers to campus to probe our knottiest media problems, including the malevolent influence of some social media platforms on the integrity of news and information. Filipino journalist and Nobel Peace Prize winner Maria Ressa, founder and CEO of Rappler.com and a clarion voice in the fight against disinformation, joined Lipinski for public conversations on the often-corrosive effects of social media as well as for more intimate discussions with Nieman Fellows battling these challenges in their own countries.
In response to declining trust in media, Lipinski advocated for increased engagement between journalists and the public. In the wake of the 2013 Boston Marathon bombing, she planned a town hall with organizations ranging from The Boston Globe to the Boston Police Department to examine breaking-news coverage in the age of social media. In 2018, as “fake news” accusations against journalism accelerated, she moderated “The Future of News: Journalism in a Post-Truth Era,” a public forum hosted by then-Harvard President Drew Faust for an overflow audience in Sanders Theatre.
Journalism’s triumphs were also recognized. At the invitation of the Pulitzer Prize Board, Nieman designed an ambitious exploration of the best of American journalism, arts, and letters — a three-day celebration of the 2016 centennial of the Pulitzer Prizes. With colleagues from the American Repertory Theater, Lipinski staged a program that opened with Wynton Marsalis, the first musician to win the Pulitzer for a jazz composition, and featured dozens of Pulitzer winners including Nieman alumnus Robert Caro on how he learned to write about power; Watergate reporter Bob Woodward, documentary filmmaker Laura Poitras, and editor Dean Baquet in animated conversation about abuses of government power; playwrights Lynn Nottage and Lin-Manuel Miranda; and Harvard historians Annette Gordon-Reed, Caroline Elkins, and Fredrik Logevall. The Sanders Theatre event was Nieman’s largest-ever public convening.
Throughout her curatorship, Lipinski worked to maintain the bonds of the fellowship worldwide through reunions, regular newsletters, and “Nieman-to-Nieman” Zoom seminars. Her favored nickname for the community, now 100 countries strong, can be found on a button given to fellows: “Nieman Nation.”
A career dedicated to journalism
Before coming to Harvard, Lipinski served as senior lecturer and vice president for civic engagement at the University of Chicago. Prior to that, she was the editor in chief and senior vice president of the Chicago Tribune. As a Tribune reporter, Lipinski was awarded a Pulitzer Prize for investigative journalism. As an editor, she oversaw a newsroom awarded Pulitzers for international reporting, feature writing, criticism, explanatory reporting, editorial writing, and investigative reporting.
Campus & Community
With Summer Youth Employment program, Harvard sees ‘an infrastructure for opportunity’
View of Cambridge and Boston skyline from Smith Campus Center. Harvard file photo
Amy Kamosa
Harvard Correspondent
February 13, 2025
5 min read
Career pathway programs help youth, veterans, Cambridge, and Greater Boston
In a few months, Harvard will welcome a new cohort of Boston
With Summer Youth Employment program, Harvard sees ‘an infrastructure for opportunity’
View of Cambridge and Boston skyline from Smith Campus Center.
Harvard file photo
Amy Kamosa
Harvard Correspondent
5 min read
Career pathway programs help youth, veterans, Cambridge, and Greater Boston
In a few months, Harvard will welcome a new cohort of Boston and Cambridge teens to work in paid positions throughout the University as part of the Summer Youth Employment program (SYEP).
For more than 25 years, the program has provided much-needed jobs and career training opportunities for dozens of local youth — more than 600 since the program’s inception.
It is one of several career pathway initiatives the University supports, the benefits of which go beyond job training for individual participants, explained Vice President for Human Resources Manuel Cuevas-Trisán. “We call them pathway programs because they create an infrastructure for opportunity.”
The University’s career pathway initiatives engage with a broad range of participants. Among those are pre-career internships through SYEP; a partnership with Year Up United (Year Up) for underserved people aged 18 to 29; internships and co-op programs for college students; mid-career initiatives such as Apprenti, which provides formal on-the-job training for various technical roles; and SkillBridge, a partnership for transitioning military veterans to the civilian workforce.
Research shows that just over 50 percent of college graduates enter the workforce underemployed and that many remain underemployed 10 years later, which can have a significant impact on economic growth locally and nationally. Internships and apprenticeship opportunities are proven approaches to combat that trend.
“These programs not only benefit Harvard directly as an employer, because they supply workforce capability that we may need at any given time, but they also help the economy in a much broader way,” said Cuevas-Trisán. “Not only does Harvard help students, staff, and faculty, through our core mission of teaching, learning, and research, but we are also a major employer in the city of Cambridge and Greater Boston. Economic growth depends on productivity and growth of the workforce, so these initiatives directly tie to our region’s economic development.
“Ultimately, it’s all about meeting a workforce need, while at the same time having a social and individual impact. Through these initiatives we give participants tools for career success. Some of them end up here and some of them elsewhere, but their passage through Harvard has been transformative, and that’s where the excitement and the real magic happens,” Cuevas-Trisán said.
The range of workforce capabilities required to ensure large universities run smoothly makes them uniquely suited to support pathway programs like those at Harvard. “We have scholars, labs, infrastructure, hospitality, and development in a scale and spectrum that is similar to a city or municipality,” he added.
Jenitha Fingfing experienced the benefit of this career opportunity spectrum as a Year Up intern last year. Fingfing accepted an offer to work at the Harvard Visitor Center in the Smith Center. At first glance, the role seemed unrelated to the data analytics she had studied in her six-month Year Up training program.
“I almost didn’t do the internship because I thought I wanted to pursue data analytics, but trusted the process and started last January,” she said. “My very first day, I had the worst case of imposter syndrome ever. But after time, I started to assimilate and feel that I actually do have a place here.”
“I’ve learned so much about Harvard culture. I say I’m getting a Harvard education by working here.”
Jenitha Fingfing, Visitor Center staff
Fingfing has since been hired as a Visitor Center staff member while she pursues a bachelor’s degree in business and management.
“I feel like landing here was exactly what I needed to propel me forward. Had I not taken the internship, or tried to stick with data analytics, it might not have gone so much in my favor. So, it definitely feels like everything happened exactly the way that it needed to,” Fingfing said. “There are always a million doors that you could open. So, I am trying to open as many as possible while I’m here and learn as much as possible. I feel really grateful to be here, and I also feel very equipped for whatever my next role may be.”
To ensure success and support Harvard departments that take on interns, programs receive regular training and assistance from Harvard Human Resources and other organizations.
“A lot of what we do is provide context setting for young people. Even though they may be taking on a small task, like making photocopies, or cleaning up data, it can be very important in terms of an institution being able to function well. They get a better sense of what the ecosystem of a workplace looks like and how we all can collectively work to make sure that everyone’s able to do their jobs well,” said Jean Dao, who manages Harvard’s public school partnership programs with local high schools and provides weekly career readiness workshops for SYEP participants.
However, Fingfing is quick to point out that the impact of simply working in an environment like Harvard provides a wealth of learning experiences on its own. “A lot of people might not realize that there’s a lot of mentorship that happens just being in the environment, listening to phone calls and being cc’d on emails. I’ve learned so much about Harvard culture, about the Visitor Center, student life, about every and anything. Really, I say I’m getting a Harvard education by working here.”
Health
Big step toward targeted molecular therapies for cancer
Brian Liau.Photos by Stephanie Mitchell/Harvard Staff Photographer
Yahya Chaudhry
Harvard Correspondent
February 12, 2025
5 min read
Researchers develop innovative approaches to understand, target, disrupt uncontrollable growth of disease
Two new studies represent a big step toward developing innovative molecular therapies
Big step toward targeted molecular therapies for cancer
Brian Liau.
Photos by Stephanie Mitchell/Harvard Staff Photographer
Yahya Chaudhry
Harvard Correspondent
5 min read
Researchers develop innovative approaches to understand, target, disrupt uncontrollable growth of disease
Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the uncontrollable growth of cancers at their roots.
In a pair of papers recently published in Nature, a team of scientists led by Harvard’s Department of Chemistry and Chemical Biology (CCB) has demonstrated how both small molecules and genetic mutations can alter the same critical protein interactions in cancer cells. These studies provide insights into two areas: discovering new “molecular glues” and understanding the impact of genetic mutations within cancer cells, setting the stage for therapeutic approaches.
“Our research has centered on understanding how specific mutations in medulloblastoma, a pediatric brain cancer, mimic the action of ‘molecular glues’ to drive oncogenic processes,” said senior author Brian Liau, associate professor of chemistry and chemical biology. “During the course of these studies, we’ve detailed the convergence of genetic mutations and chemical modalities that alter protein interactions.”
Molecular glues are small molecules that force two proteins that normally wouldn’t interact to bind. That triggers a cell’s natural “garbage disposal system” to degrade one of the proteins. Researchers have been exploring the possibility of using molecular glues to target disease-causing proteins.
Until now, many of these interactions went unexploited because of their complexity and difficulty to find. This research, however, unveils a new scaffold and mechanism that can be used to design molecular glues to influence specific protein interactions and functions.
This work was led by members of Liau’s lab, including co-authors Megan Yeo, Olivia Zhang, Ceejay Lee, Idris Barakat, and Nicholas Chen (all Ph.D. students in the Griffin Graduate School of Arts and Sciences in CCB); postdocs Jiaming Lee, Pallavi Gosavi, Hui Si Kwok, Stefan Harry, and Amanda Waterbury, and research assistant Irtiza Iram. Additional contributions were provided by scientists at Harvard Medical School as well as the Broad Institute, the University of Washington, and St. Jude Children’s Research Hospital.
Brian Liau (front center) with his team in the Converse Laboratories. From left: Megan Yeo, Hui Si Kwok, Amanda Waterbury, Irtiza Iram, Stefan Harry, Liau, Nicholas Chen, and Idris Barakat.
One study explored how molecular glues alter essential protein interaction networks. The researchers showed that the molecule UM171 works as a glue that can trigger the breakdown of the CoREST complex, an organizing system that controls access to genes. UM171 works by engaging with a protein called histone deacetylase (HDAC), which is part of a larger complex with CoREST, and gluing it to another protein named KBTBD4, which is an effector enzyme of protein degradation. These findings demonstrate new ways for glues to be used to target proteins traditionally considered undruggable, like CoREST, providing new strategies for drug design.
“How this small molecule works was a big question in the field because at the time no one knew for sure that it was a molecular glue,” said Zhang. “We came at this problem with a multidisciplinary approach, leveraging both functional genomics and structural biology to give us new insights.”
In the companion study, the researchers investigated cancer-causing mutations in the KBTBD4 protein, often mutated in a type of brain cancer. These mutations can turn normal cell interactions into harmful ones by changing how proteins connect, causing aberrant degradation of the CoREST complex.
The team was able to identify which mutations in KBTBD4 contribute to cancer. They then used cryo-electron microscopy (cryo-EM) to “see” these mutations at the atomic level. Combining these techniques, the team discovered that cancer mutations alter protein structure and function, mirroring the interaction of UM171 and KBTBD4.
“It’s very hard to imagine what these insertion mutations actually do without a structure since they occur in a flexible region of the protein, so having the cryo-EM structure was very helpful,” Yeo said. “It was stunning to see the direct overlay of the small molecule and these cancer mutations, which we could not have imagined without this technology.”
A defining feature of this research was its focus on “convergence,” where a small molecule and a genetic mutation precisely mimic the effects of one another functionally and structurally.
In Liau’s lab, the researchers explored how understanding one mechanism can inform the development and application of the other.
“It’s really hard to find these types of molecular glue molecules, so if you could actually use genetics to look for them, it would be very helpful,” Liau said. “This chemical genetic convergence is a new paradigm.”
Going forward, Liau’s lab plans to further explore these molecular strategies, searching for more instances of genetic mutations that can induce new protein interactions to aid chemical design. The implications of this research offer a new strategy toward understanding and targeting proteins for small molecule drug discovery.
“I’m excited about the potential directions our research can take,” Liau said. “The implications extend beyond cancer, possibly reshaping our approach to studying a variety of diseases.”
The research described in this story received funding from the National Institute of General Medical Sciences and the National Institute of Health’s National Cancer Institute.
Deans Nancy Coleman and Hopi Hoekstra discuss the evolution of DCE.Images courtesy of DCE/One Brattle Studios
Campus & Community
DCE celebrates 50 years of innovation and impact
Yearlong fete kicks off with a look at the future of continuing education
Harry Pierre
DCE Communications
February 12, 2025
3 min read
The Division of Continuing Education began its yearlong celebration of its
Yearlong fete kicks off with a look at the future of continuing education
Harry Pierre
DCE Communications
3 min read
The Division of Continuing Education began its yearlong celebration of its 50th anniversary last week with a virtual kickoff event highlighting the division’s lead at the forefront of shaping the future of continuing education.
Now encompassing Harvard Extension School, Harvard Summer School, Harvard DCE Professional & Executive Development, and Harvard Institute for Learning in Retirement, DCE is considered one of the most diverse academic units at Harvard University.
The online event brought together alumni, faculty, staff, and students for a reflection on the past, a discussion of the present, and an exciting glimpse into the future.
In his opening message, President Alan Garber emphasized the importance of DCE’s place within the University, highlighting its role in allowing a broader spectrum of learners access to the institution.
Since its founding in 1975, DCE “has opened the doors of the University wide,” said Garber, adding that the thousands who have experienced Harvard through DCE are pursuing “their academic interests in an educational environment that embraces change and encourages innovation.”
His remarks set the tone for the event, reinforcing the DCE’s commitment to access and academic excellence.
DCE Dean Nancy Coleman and Hopi Hoekstra, the Edgerley Family Dean of the Faculty of Arts and Sciences, discussed the evolution of DCE and its numerous achievements. The oldest institutions, Harvard Extension School and Harvard Summer School, have been able to weave in its two “younger” departments — the Harvard Institute for Learning and Retirement and its Professional & Executive Development programs, noted the deans.
“The result is four academic units under one roof that truly bring learners together across their lifetime,” Coleman said. “In theory, a student could begin at DCE Harvard Summer School at 16 years of age and return multiple times throughout their lifetime to continue learning.”
Hoekstra remarked that DCE was a “special place that brings tremendous value not only to the FAS, but to the entire University and beyond.” She emphasized how DCE is rooted in the Harvard community, advancing innovation and access and extending opportunities globally for all learners.
Reflecting on the journey was Michael Shinagel, who was appointed DCE’s first dean in 1975 by then-FAS Dean Henry Rosovsky. Shinagel was the longest serving dean in Harvard history, leading DCE for nearly 40 years at the time of his retirement in 2013. He explained he was deeply passionate about the mission of continuing education and the opportunities it provides.
When asked by Coleman what he sees for the next 50 years, Shinagel laughed and said, “Nothing is permanent except change. And nothing changes more than, I think, continuing education. But where are we at the cutting edge? Where are we always testing, and so on? It’s continuing education.”
Illustration by Judy Blomquist/Harvard Staff
Nation & World
U.S. students need to start showing up
Liz Ross
Harvard Graduate School of Education
February 11, 2025
8 min read
Detailing latest recovery scorecard, Ed School researcher urges broader action to reduce absenteeism and a sharper focus on targeted catch-up efforts
For the latest report from the Education Recovery Scorecard, c
Detailing latest recovery scorecard, Ed School researcher urges broader action to reduce absenteeism and a sharper focus on targeted catch-up efforts
For the latest report from the Education Recovery Scorecard, co-authored by Harvard’s Thomas Kane and released Tuesday, researchers compared academic recovery in math and reading for individual school districts enrolling 35 million students in 43 states. Among the findings: Students are moving in the “wrong direction” in reading; tutoring seems to reward investment; and chronic absenteeism continues to be a drag on student performance.
The report — a collaboration among the Center for Education Policy Research at Harvard, the Educational Opportunity Project at Stanford University, and faculty at Dartmouth College — comes months after the expiration of federal relief funding for K-12 schools. Federal aid of approximately $190 billion was distributed to schools, which had until September to use the money.
In this edited interview with the Gazette, Kane, director of the Center for Education Policy Research and a professor at the Harvard Graduate School of Education, details both the latest results and the launch of a Harvard-led initiative to help states identify and share evidence-based policies to reduce chronic absenteeism and to improve reading and math skills.
You’re now in the third year of producing the scorecard. How would you describe the student recovery story at this point?
Students have continued to recover slowly in math, although the average student is still almost half a grade level behind. In reading, rather than recovering, students are going in the wrong direction, losing more ground between 2022 and 2024. The loss in literacy came despite initiatives to implement the “science of reading” in many states, including Massachusetts.
Literacy levels were declining even before the pandemic, correct?
There has been a slow decline since 2015, especially among those with weak reading skills. Not all of the losses that we’re seeing are due to what happened, or didn’t happen, with in-person or remote instruction during 2020 and 2021. Some of it has been due to trends that started before the pandemic.
National test scores (Grades 3-8, 2003-2024)
Source: “Pivoting from Pandemic Recovery to Long-Term Reform: A District-Level Analysis”
But some of it has been due to trends that started with the pandemic. For example, if the pandemic was an earthquake, the subsequent rise in absenteeism has been a tsunami that is continuing to disrupt learning.
There are areas of success that you point to in some higher poverty districts, including Compton, California, and Ector County in Texas. What has been the difference-maker?
It’s too early to say which strategies worked generally, but we can see the districts that recovered and we’re beginning to learn what they did. For instance, in Ector County, which includes Odessa, the district shifted to outcomes-based contracts for tutors. Tutoring contractors didn’t receive full payment unless students reached targets in terms of attendance and improvements in math and reading scores. Other places like Birmingham, Alabama, hired math coaches that helped teachers improve math achievement. So, there wasn’t one strategy that successful districts used. The most generalizable evidence of efficacy has been for high-dosage tutoring and summer learning.
The story seems to be that changes happened not so much at the state level, but from district to district. Can you explain the level of variation in test scores?
Ninety percent of the federal pandemic relief went directly to school districts. The federal Department of Education and state departments of education were given very little authority to coordinate efforts or encourage districts to spend the dollars in one way or another. This was an extreme example of devolution, of handing the money directly to local districts to decide. Some districts were more successful than others in helping students catch up.
Was the federal relief money effective?
Among districts with similar poverty rates and other characteristics, those receiving more federal funding caught up faster. The impact per dollar was about what prior research suggested you would get from a general revenue increase. It really depended on how districts spent the money. In California, where we had more details on spending, we saw that districts that spent more on academic interventions, such as tutoring and summer learning, as opposed to across-the-board salary increases, saw faster catchup.
The diluted impact of the pandemic relief on academic recovery was a result of the American Rescue Plan law; it granted tremendous flexibility to local communities to decide how to spend the money. They were only required to spend 20 percent on academic recovery. Some focused more on academic recovery than others.
The report shows increases in socioeconomic and racial disparities in math and, to a lesser extent, reading achievement. Can you talk more about that trend?
Horace Mann famously described public schools as “the balance wheel of the social machinery.” We definitely saw that in effect during the pandemic. When schools closed, losses were larger in higher-poverty districts. That has continued as chronic absenteeism has risen around the country. Although absenteeism has increased in most districts, it has grown more in higher-poverty schools. Each day missed is going to be more costly for students in higher-poverty districts.
“If the pandemic was an earthquake, the subsequent rise in absenteeism has been a tsunami that is continuing to disrupt learning.”
Veasey Conway/Harvard Staff Photographer
Now that all the federal relief dollars have been spent, the focus of your work appears to be shifting from short-term recovery efforts to longer-term reform. What should the priorities be for states and districts moving forward?
We’re trying to shift the conversation away from debating how the federal money was being used or misused toward deciding what must be done now. The top priority must be identifying funds to continue targeted academic catch-up efforts, like tutoring and summer learning. For instance, states are allowed to set aside 3 percent of federal Title I dollars for direct student services like tutoring. Currently, only one state exercises that authority — Ohio.
Second, we need a broad-based effort to lower absenteeism. Until now, we’ve left the responsibility for recovery entirely on the shoulders of principals, superintendents, and teachers. But lowering absenteeism is one of the few things that community leaders outside of schools could be helping with now. That could be through public information campaigns or through science museums supporting extracurricular activities at school to make school more attractive for students. Employers could be asking their employees if they need flexibility for school pick-up and drop-off activities.
A third thing is to ask teachers to inform parents when their child is below grade level. From the very beginning of the recovery, polls have shown that parents underestimate the impact of the pandemic on their child’s learning. Teachers know kids are behind, but it hasn’t affected the grades they give. If parents continue to think their own children are fine, they aren’t going to sign up for summer learning, they’re not going to be as concerned about absenteeism, and they may resist the types of changes, such as extending the school year, that may be required to help students catch up.
Your research center recently announced an initiative focused on states and districts learning from one another. How will this project work?
One potential strength of the U.S. system is that states and districts are choosing different solutions to shared problems such as absenteeism and declining literacy: “science of reading” initiatives vary dramatically from state to state; many, but not all, districts have implemented cellphone bans. I say it’s a “potential strength” because in order to benefit from it, we need to learn which interventions are working and which are not. States cannot learn from looking solely at what’s happening within their own borders; they need to see what’s working in other states.
Unfortunately, there’s no one organizing a cross-state effort focused on efficacy. Even if the policy debate in D.C. were less polarized, it would be awkward for the federal government to evaluate the efficacy of state reforms. I think that’s a role that a national university such as Harvard can play. We’ve launching a cross-state effort, called the “States Leading States” project. We’re going to work with a group of four or five states over the next few years to learn about the efficacy of various policies — including those focused on improving literacy, reducing chronic absenteeism, and boosting middle school math. We will work with states to learn what’s working and then spread what we learned to other states, through inter-state organizations such as the National Council of State Legislators, the National Governors Association, and the Council of Chief State School Officers. I can’t think of anything more important right now than supporting those state leaders who are willing to follow the evidence.
Imam Khalil Abdur-Rashid (left) and Rabbi Getzel Davis.Photos by Veasey Conway/Harvard Staff Photographer
Campus & Community
Key to healing riven communities? Getting people together.
Liz Mineo
Harvard Staff Writer
February 11, 2025
5 min read
Campus rabbi, imam work to ease pain in their groups caused by Israel-Hamas war, model power of personal ties
Part of a series of profiles foc
Key to healing riven communities? Getting people together.
Liz Mineo
Harvard Staff Writer
5 min read
Campus rabbi, imam work to ease pain in their groups caused by Israel-Hamas war, model power of personal ties
Part of a series of profiles focused on community-led efforts to promote dialogue across campus.
Many Muslim students used to regularly dine at Harvard Hillel as much of the kosher cuisine is also halal. And students of both traditions would join to host Sukkat Salaam, an annual interfaith dinner to celebrate the Jewish holiday of Sukkot, campus religious leaders say.
But the Oct. 7 terror attacks changed all that, damaging the sense of collegiality and community between the two groups, with lines drawn between pro-Israeli and pro-Palestinian supporters, according to campus Rabbi Getzel Davis and Muslim Chaplain Khalil Abdur-Rashid. Seeing the pain in their communities, the two chaplains joined forces to support each other and help bring their communities back together.
So far, reticence remains, and progress has been slow. But the two intend to persevere. They are convinced that the answer will eventually reside in restoring and strengthening personal connections between individual members of the communities, an effort they model.
“Given the divisions that were forming on campus, we knew that we had to be in relationship with each other,” said Davis, who has been working at Harvard Hillel for over 10 years. “We supported each other as colleagues and worked to bring together our communities, both of which are still in very difficult places and feeling a lot of alienation and a lot of fear.”
Since November of last year, the two have held weekly meetings, in which they mourned together, shared meals, met each other’s families, and built a strong bond of friendship.
“The thing that really drew me to Khalil was his deep care for his community and psychological training which is something we both share,” Davis said. “We also speak a lot about the deep commonalities in experience Jewish and Muslim students experience on campus today — both the amazing opportunities and also the challenges of being religious minorities.”
“One thing I can say about him is that his kids and family are the world to him,” Adbur-Rashid noted of Davis. And he added, “He also loves to work out, something I admire in him.”
“It’s scary for some people who want to cancel other narratives to suggest that two people who are legitimately different could care about each other.”
Rabbi Getzel Davis
Initially, the chaplains were singularly focused on preserving the work done through the Harvard Interfaith Forum, which was launched in 2014 to promote religious, spiritual, and ethical awareness and understanding on campus.
“We both wanted to protect the work students have done in the interfaith realm,” said Abdur-Rashid, who became Muslim chaplain in 2017. “And there was a need to find ways to bring students together and push back against efforts from off-campus groups to keep our students polarized.”
They came up with several ideas, including a communal mourning circle, an outdoor meditation activity, a joint field trip, and an interfaith iftar, but they all failed to materialize. Students were too hurt, too angry, and too scared to take part in activities with members of other faith communities, said Davis.
Realizing the deep emotions and the alienation felt by students, the religious leaders decided to ease off on interfaith events. Instead, they focused on helping their own communities find comfort and support in each other. “Both of our communities were dealing with significant fear and trauma,” said Abdur-Rashid. “We had to allow our student communities to heal inside first.”
Davis and Abdur-Rashid co-led an interfaith vigil outside Memorial Church last year.
Harvard file photos
There have been signs of the beginning of change, however. An interfaith vigil on the steps of Memorial Church held last year highlighted the importance of mourning together. A community dialogue series on what it means to be a good neighbor, led by five Harvard chaplains, drew a wide audience. And at last year’s Commencement, both Davis and Abdur-Rashid gave the opening benediction to the graduating class.
“We wrote our blessings in dialogue with each other, speaking distinctively from our own traditions, but in resonance with each other,” said Davis. “We wanted to model for others how we could be together through difference.”
The two religious leaders say building community with others from different backgrounds or religions, based on tolerance and respect, is not only possible but also critical, as is standing together against hate.
“There’s a lot of people who want to believe that it’s not possible that we could be friends with people who are different than us,” said Davis. “It’s scary for some people who want to cancel other narratives to suggest that two people who are legitimately different could care about each other.”
“One’s identity is important, but one only knows oneself through the discovery of others.”
Imam Khalil Abdur-Rashid
Despite the challenges, Davis and Abdur-Rashid believe the rifts across the University will be repaired. The University’s work to combat both antisemitism and Islamophobia over the last year makes them feel more optimistic. For the Muslim chaplain, the way to deal with different perspectives demands an interdisciplinary approach from academia to religion to ethics.
“We live in a world of robust diversity, one might even call it inescapable diversity,” said Abdur-Rashid. “The paradoxical beauty in that is that we learn more about ourselves through our encounters with difference. One’s identity is important, but one only knows oneself through the discovery of others.”
Davis agreed. “Being able to be friends across difference or to be in relationship with people who are different from us is important for future leaders of men,” he said. “There are many in the Jewish community and in the Muslim community that are feeling afraid and alienated, and the best antidote to that is togetherness.”
Health
Cancer claims are everywhere. Which to trust?
Illustrations by Liz Zonarich/Harvard Staff
Sy Boles
Harvard Staff Writer
February 11, 2025
1 min read
Our research-based quiz can help
There is no shortage of information about cancer risk in the news, at the water cooler, and on social media feeds. To help separate fact from fabrication, researchers at the Harvard T.H. Chan School of
There is no shortage of information about cancer risk in the news, at the water cooler, and on social media feeds. To help separate fact from fabrication, researchers at the Harvard T.H. Chan School of Public Health created the Cancer FactFinder. The online tool allows users to look up common claims about cancer risk to find out whether they are supported or debunked by research.
Timothy Rebbeck, Vincent L. Gregory Jr. Professor of Cancer Prevention and the FactFinder’s editor in chief, helped us develop the following quiz to help readers make healthier choices.
Dara Olmsted Silverstein.
Campus & Community
Class of 2000 elects Dara Olmsted Silverstein as chief marshal of alumni
Food sustainability advocate to serve in longstanding alumni tradition
February 11, 2025
3 min read
Food sustainability expert Dara Olmsted Silverstein ’00 will be chief marshal of alumni at this spring’s Harvard Alumni Day celebration, the Harvard Alumni Association (HAA) has announc
Class of 2000 elects Dara Olmsted Silverstein as chief marshal of alumni
Food sustainability advocate to serve in longstanding alumni tradition
3 min read
Food sustainability expert Dara Olmsted Silverstein ’00 will be chief marshal of alumni at this spring’s Harvard Alumni Day celebration, the Harvard Alumni Association (HAA) has announced.
Silverstein previously worked at the Harvard Office for Sustainability for eight years, focusing on topics including renewable energy and behavior change. She also led Harvard Dining Services’ Food Literacy Project — which fosters a holistic understanding of food through education on sustainability, nutrition, and food preparation — hosting student fellowships and guiding initiatives across campus and across the Cambridge community to help people make more informed choices.
While living in Boston, she wrote for the Boston Globe’s Green Blog. She also received a master’s degree from Tufts University in environmental policy.
Subsequently, she served as the sustainable food program manager at Stanford University’s Residential and Dining Enterprises, where she educated the Stanford community on sustainable food systems and collaborated on projects with faculty and students to spur innovations.
Silverstein was president of the Nueva School Parent Association and is currently an editor for Kiva, a microfinance nonprofit that helps expand financial access to underserved communities. A committed philanthropist, she and her husband have created an endowed engineering scholarship at Cornell University and an endowed scholarship at Harvard College.
“Dara’s unwavering dedication to sustainability and her commitment to strengthening the alumni community are inspiring. I am delighted that she will represent alumni as chief marshal on Harvard Alumni Day,” says Moitri Chowdhury Savard ’93, alumni president of the HAA, who will serve as this year’s Alumni Day program host.
Elected by her classmates, Silverstein carries on a tradition that is more than 125 years old. As chief marshal, her ceremonial duties include leading the alumni parade through Tercentenary Theatre on Harvard Alumni Day and hosting a special luncheon for University and alumni leaders, dignitaries, and this year’s Harvard Medalists.
A first-generation college student, Silverstein concentrated in social anthropology and was a tutor in Mather House for four years, in both resident and nonresident capacities. She also won the Derek Bok Award for Excellence in Graduate Student Teaching.
An active Harvard volunteer and alumni interviewer, she has served her class in a number of roles, including secretary, treasurer, and five-time reunion co-chair. Silverstein also produces a class newsletter and has hosted virtual events featuring authors, filmmakers, and politicians. In addition, she recently launched a podcast interviewing her classmates leading up to their reunion.
“When I signed up to be class secretary at age 21, never in my wildest dreams did I imagine I would still be doing it 25 years later,” Silverstein says. “I’ve found that keeping my class connected is one of my favorite things to do, and it’s because I have a truly phenomenal cohort of inspiring peers who have all impacted our world in their own way. I am honored to represent them.”
All alumni are invited to attend a full day of festivities in Cambridge on June 6, which includes the traditional alumni parade through Tercentenary Theatre, special guest speakers, symposia sessions, alumni meetups, and a party in the Yard with food trucks and lawn games. For those unable to make it to campus, virtual celebrations and local events will be held worldwide.
Rebecca Weintraub Brendel, director of Harvard Medical School’s Center for Bioethics.Veasey Conway/Harvard Staff Photographer
Health
It’s inoperable cancer. Should AI make call about what happens next?
Arrival of large-language models sparking discussion of how use of technology may be broadened in patient care, and what it means to be human
Alvin Powell
Harvard Staff Writer
February 10, 2025
8 min read
It’s inoperable cancer. Should AI make call about what happens next?
Arrival of large-language models sparking discussion of how use of technology may be broadened in patient care, and what it means to be human
Alvin Powell
Harvard Staff Writer
8 min read
AI is already being used in clinics to help analyze imaging data, such as X-rays and scans. But the recent arrival of sophisticated large-language AI models on the scene is forcing consideration of broadening the use of the technology into other areas of patient care. In this edited conversation with the Gazette, Rebecca Weintraub Brendel, director of Harvard Medical School’sCenter for Bioethics, looks at end-of-life options and the importance of remembering that just because we can, doesn’t always mean we should.
When we talk about artificial intelligence and end-of-life decision-making, what are the important questions at play?
End-of-life decision-making is the same as other decision-making because ultimately, we do what patients want us to do, provided they are competent to make those decisions and what they want is medically indicated — or at least not medically contraindicated.
One complication would be if a patient is so ill that they can’t tell us what they want. The second challenge is understanding in both a cognitive way and an emotional way what the decision means.
People sometimes say, “I would never want to live that way” but they wouldn’t make the same decision in all circumstances. Patients who’ve lived with progressive neurologic conditions like ALS for a long time often have a sense of when they’ve reached their limit. They’re not depressed or frightened and are ready to make their decision.
On the other hand, depression is quite prevalent in some cancers and people tend to change their minds about wanting to end their lives once symptoms are treated.
So, if someone is young and says, “If I lose my legs, I wouldn’t want to live,” should we allow for shifting perspectives as we get to the end of life?
When we’re faced with something that alters our sense of bodily integrity, our sense of ourselves as fully functional human beings, it’s natural, even expected, that our capacity to cope can be overwhelmed.
But there are pretty devastating injuries where a year later, people report having a better quality of life than before, even for severe spinal cord injuries and quadriplegia. So, we can overcome a lot, and our capacity for change, for hope, has to be taken into account.
So, how do we, as healers of mind and body, help patients make decisions about their end of life?
“I’d be hard-pressed to say that we’d ever want to give away our humanity in making decisions of high consequence.”
For someone with a chronic illness, the standard of care has those decisions happening along the way, and AI could be helpful there. But at the point of diagnosis — do I want treatment or to opt for palliation from the beginning — AI might give us a sense of what one might anticipate, how impaired we might be, whether pain can be palliated, or what the tipping point will be for an individual person.
So, the ability to have AI gather and process orders of magnitude more information than what the human mind can process — without being colored by fear, anxiety, responsibility, relational commitments — might give us a picture that could be helpful.
What about the patient who is incapacitated, with no family, no advance directives, so the decision falls to the care team?
We have to have an attitude of humility toward these decisions. Having information can be really helpful. With somebody who’s never going to regain capacity, we’re stuck with a few different options. If we really don’t know what they would like, because they’re somebody who avoided treatment and really didn’t want to be in the hospital, or didn’t have a lot of relationships, we assume that they wouldn’t have sought treatment for something that was life-ending. But we have to be aware that we’re making a lot of assumptions, even if we’re not necessarily doing the wrong thing. Having a better prognostic sense of what might happen is really important to that decision, which, again, is where AI can help.
I’m less optimistic about the use of large-language models for making capacity decisions or figuring out what somebody would have wanted. To me it’s about respect. We respect our patients and try to make our best guesses, and realize that we all are complicated, sometimes tortured, sometimes lovable, and, ideally, loved.
Are there things that AI should not be allowed to do? I’m sure it could make end-of-life recommendations versus simply gathering information.
We have to be careful where we use “is” to make an “ought” decision.
If AI told you that there is less than 5 percent chance of survival, that alone is not enough to tell us what we ought to do. If there’s been a terrible tragedy or a violent assault on someone, we would look at that 5 percent differently from someone who’s been battling a chronic illness over time and says, “I don’t want to go through this again, and I don’t want to put others through this. I’ve had a wonderful life.”
“If AI told you that there is less than 5 percent chance of survival, that alone is not enough to tell us what we ought to do.”
In diagnostic and prognostic assessments, AI has already started to outperform physicians, but that doesn’t answer the critical question of how we interpret that, in terms of what our default rules should be about human behavior.
It can help us be more transparent and accountable and respectful of each other by making it explicit that, as a society, if these things happen, unless you tell us otherwise we’re not going to resuscitate. Or we are when we think there’s a good chance of recovery.
I don’t want to underestimate AI’s potential impact, but we can’t abdicate our responsibility to center human meaning in our decisions, even when based on data.
So these decisions should always be made by humans?
“Always” is a really strong word, but I’d be hard-pressed to say that we’d ever want to give away our humanity in making decisions of high consequence.
Are there areas of medicine where people should always be involved? Should a baby’s first contact with the world always be human hands? Or should we just focus on quality of care?
I would want people around, even if a robot does the surgery because the outcome is better. We would want to maintain the human meaning of important life events.
Another question that comes up is, what will it mean to be a physician, a healer, a healthcare professional? We hold a lot of information and an information asymmetry is one of the things that has caused medical and other healthcare professionals to be held in high esteem. But it’s also about what we do with the information, being a great diagnostician, having an exemplary bedside manner, and ministering to patients at a time when they’re suffering. How do we redefine the profession when the things we thought we were best at, we may not be the best at anymore?
At some point, we may have to question human interaction in the system. Does it introduce bias, and to what extent is processing by human minds important? Is an LLM going to create new information, come up with a new diagnostic category, or a disease entity? What ought the responsibilities of patients and doctors be to each other in a hyper-technological age? Those are important questions that we need to look at.
Are those conversations happening?
Yes. In our Center for Bioethics, one of the things that we’re looking at is how does artificial intelligence look at some of our timeless challenges within health? Technology tends to go where there’s capital and resources, while LLMs and AI advances could allow us to care for swaths of the population where there’s no doctor within a day’s travel. Holding ourselves accountable on questions of equity, justice, and advancing global health is really important.
There are questions about moral leadership in medicine. How do we make sure that output from LLMs and future iterations of AIs comport with the people we think we are and the people we ought to be? How should we educate to make sure that the values of the healing professions continue to be front and center in delivering care? How do we balance the public’s health and individual health, and how does that play out in other countries?
So, when we talk about patients in under-resourced settings and about AI’s capabilities versus what it means to be human, we need to be mindful that in some parts of the world to be human is to suffer and not have access to care?
Yes, because, increasingly, we can do something about it. As we’re developing tools that can allow us to make huge differences in practical and affordable ways, we have to ask, “How do we do that and follow our values of justice, care, respect for persons? How do we make sure that we don’t abandon them when we actually have the capacity to help?”
Science & Tech
What electric fish can teach scientists about NeuroAI
The elephantnose fish, a weakly electric fish named for the trunk-like protrusion on its head, was studied by researchers.
Yohan J. John
Harvard Correspondent
February 10, 2025
5 min read
Modeling their behaviors may help in development of new AI systems
Electric fish are among the most intriguing specimens in natur
What electric fish can teach scientists about NeuroAI
The elephantnose fish, a weakly electric fish named for the trunk-like protrusion on its head, was studied by researchers.
Yohan J. John
Harvard Correspondent
5 min read
Modeling their behaviors may help in development of new AI systems
Electric fish are among the most intriguing specimens in nature’s cabinet of curiosities. They “see” their world and each other by sensing — and generating their own — electric fields. This unique ability provides a key area of exploration for the emerging field of NeuroAI, which explores the perceptual and cognitive capacities of both natural and artificial systems.
For Kanaka Rajan, Kempner Institute investigator and associate professor in the Department of Neurobiology at Harvard Medical School, electric fish represent a potential source of wider insight into “collective intelligence,” which emerges from interactions among different goal-oriented entities.
Rajan and her team believe that studying weakly electric fish might be a steppingstone to understanding multi-agent intelligence, potentially shedding light on the complex dynamics that are a hallmark of animal and human societies.
Rajan and her collaborators investigated the Gnathonemus petersii, or Peter’s elephantnose fish, a weakly electric fish named for the trunk-like protrusion on their heads. Native to the rivers of western and central Africa, elephantnose fish prefer to live in muddy pools and shady, slow-moving streams. With the help of electro-sense, the fish are able to penetrate their muddy environments by producing pulses known as electric organ discharges, or EODs.
“They do everything in their lives through electric pulses,” says Rajan. “Their communication, their mating habits, their pursuit, their aggression, cooperation, competition, everything is governed by these pulses that they emit.”
Because Rajan and her team are interested in how agents — which could be humans, animals, robots, or language models — interact with each other at different scales, elephantnose fish offer an opportunity to study emergent, coordinated communication, or agent interaction, in a relatively simple context.
Here’s where the weakly electric fish come in. Their “language” consists of streams of identical electrical pulses. Their “sentences” vary in terms of how often these “syllables” are emitted by each fish. But even though these animals’ forms of communication are simpler than humans’, they still display emergent, coordinated behaviors that could shed light on much more complex social dynamics. Modeling these behaviors can also help in the development of new AI systems.
The key idea when studying collective intelligence is that social dynamics are not simply the sum of individual behaviors, or even of pairwise interactions. For example, the distinctive behaviors that can arise in groups of humans at a party are much more complex than a collection of two-person conversations. This could be because each conversation carries with it a memory remnant from the previous conversation, even if it occurred with an entirely different person, or because a three-way discussion has nuances that cannot be captured wholly by the sum of every possible two-person chat. Plus, the overall context matters when it comes to human behaviors — whether it is a work or an after-work event, for example, or whether the situation takes place between peers or within a social hierarchy.
Elephantnose fish demonstrate this sort of collective intelligence in striking ways. In a study by Federico Pedraja and Nathaniel Sawtell, one of Rajan’s key collaborators at Columbia University, elephantnose fish in a group were seen to piggyback off each other’s ability to search for food. If one fish happens to find a promising source of food, it can send out pulses that nearby fish can detect. As a result, other fish can expend less energy on foraging directly and simply follow the leader. Through this and other types of collective communication, the fish are able to exhibit social behaviors that can help them survive and thrive in certain environments.
Rajan and her team built computer models using artificial agents that mimic elephantnose fish. By manipulating factors that would be impossible to control experimentally in real fish, Rajan and her team were able to simulate and study how collective intelligence emerges in different contexts.
Their work at the Kempner Institute has begun to reveal some fascinating results. Evolutionary simulations, in which artificial fish must survive in order to pass on their characteristics to the next generation, suggest that the availability of food determines whether the fish engage primarily in cooperation or in competition. Reducing the reliability of food sources increases the likelihood that the population will engage in competitive behaviors. Cooperation and competition aren’t hardwired into these artificial agents. Rather, these behaviors emerge over the course of multiple generations through a simulated version of natural selection.
Rajan aims to expand this project to gradually encompass more and more complexity, including better understanding the process of learning in individual agents and the emergence of different survival strategies.
One key question the team is starting to address is whether there are universal laws governing social interactions. Is there, for example, a “critical mass” of agents that can optimally cooperate? Or a threshold after which competition becomes excessive?
This kind of work has intriguing implications for human cooperation but is also relevant to applied AI research. Principles of collective intelligence may play an important role in how individual AI systems interact and communicate with one another. Cooperative teams of AI agents — sometimes referred to as “swarms” — are promising for tech applications, potentially allowing for faster, more complex, and more adaptable problem-solving. Only time will tell if such AI “hive minds” prove useful, but in the meantime, foundational work of the kind pursued by Rajan and her collaborators is shedding light on how both biological and artificial agents can work together to produce collective intelligence.
Nation & World
Class surges as factor in who gets sent to prison
Incarceration rates fall for Black Americans, soar for white Americans without college education, finds study
Nikki Rojas
Harvard Staff Writer
February 10, 2025
5 min read
Christopher Muller. Niles Singer/Harvard Staff Photographer
The incarceration rate of Black Americans has fallen sharply in the 21st century, accordin
Incarceration rates fall for Black Americans, soar for white Americans without college education, finds study
Nikki Rojas
Harvard Staff Writer
5 min read
Christopher Muller.
Niles Singer/Harvard Staff Photographer
The incarceration rate of Black Americans has fallen sharply in the 21st century, according to a new study, but the trend has coincided with a rise in imprisonment of white Americans with no college education.
“The good news is that there have been absolute declines in the rate of imprisonment among Black Americans both with and without a college education,” said Christopher Muller, co-author of the study published in Proceedings of the National Academy of Sciences and professor of sociology at Harvard. “It seems likely, given what we’re seeing in the data, that some of this has to do with the de-escalation of the drug war.
“The bad news is that some of the decline in racial inequality is driven by increases in the prison admission rate of white Americans with no college education, and that’s happening for all offense types.”
Data showed that from 1984 to 2019, the number of white Americans with no college education sent to prison more than doubled from roughly 60,000 in 1984 to around 160,000 in 2019.
Muller and Alexander Roehrkasse, assistant professor of sociology and criminology at Butler University, analyzed decades of administrative and survey data from the National Corrections Reporting Program, the National Prisoner Statistics Program, and the Current Population Survey. They found that educational inequality is now greater than racial inequality in imprisonment rates for all major crimes.
“The economic prospects of Black Americans born poor have improved, while the economic prospects of white Americans born poor have worsened.”
Christopher Muller
“We can’t say what the causes are, but it’s striking that our results mirror trends in life expectancy and intergenerational mobility. For instance, recent research from Harvard’s Opportunity Insights shows that the economic prospects of Black Americans born poor have improved, while the economic prospects of white Americans born poor have worsened,” Muller said.
Research by Princeton economists Anne Case and Angus Deaton has found similar results when looking at life expectancy. While life expectancy for Black Americans has been rising, the opposite is true for white Americans with no college education.
“Case and Deaton note that the large-scale job loss among low-education workers that hit Black Americans in the mid-20th century began to affect low-education white Americans in the 21st century,” Muller said. Meanwhile, Muller and Roehrkasse’s new study found that the white no-college imprisonment rate growth included rises in all crime categories.
Muller and Roehrkasse say their new work helps to show why racial inequality and incarceration for drug offenses have been a major focus of previous research. In 1971, for example, then President Richard Nixon launched America’s war on drugs, a governmental effort that heavily penalized those who sell or use drugs. Subsequent federal legislation, including the Anti-Drug Abuse Act in 1986 and the Crime Bill in 1994, established harsher drug sentences that disproportionally affected Black Americans, Muller said.
The incarceration rate for Black Americans with no college education sentenced for drug offenses has been “astronomically high,” said Muller. In 1992, Black Americans with no college education were 14 times likelier to be sent to prison for drug offenses than their white counterparts in the same education group.
“Given these numbers, it’s easy to understand why there has been so much attention paid to racial inequality in imprisonment for drug offenses,” Muller said. By 2019, though, the Black-white prison admission ratio among Americans with no college education had fallen to 1.5. “That’s still a substantial disparity, but it has fallen by a lot,” he said.
According to their findings, the imprisonment rate of Black Americans with no college education for drug offenses rose from 100 per 100,000 in 1984 to 1,405 per 100,000 in 1999. That rate ultimately dropped to 494 per 100,000 in 2019. Data from 2019 onward, including the COVID pandemic, was not included.
Roehrkasse added: “People shouldn’t misunderstand our paper to be saying that the prosecution and imprisonment of people for drug offenses doesn’t matter anymore. Drug offenses are still a meaningful portion of prison admissions today and account for a meaningful proportion of the disparities in admissions.”
Muller noted that Black Americans still bear a disproportionate share of the indirect harm of incarceration due to long historical legacies.
“Middle-class Black Americans are more likely than middle-class white Americans to live in poor neighborhoods, and because of historically low levels of wealth among Black families, middle-class Black Americans are also more likely than comparable white Americans to have poor family members,” he said. “As a result, Black Americans with high levels of education and income are more likely than white Americans with low levels of education and income to have an imprisoned family member or to live in a neighborhood with a high imprisonment rate.”
Muller and Roehrkasse already have their eyes on their next research objective. “The obvious next step is to try to understand the causes of the trends we document,” Muller said. “For example, to what extent was the decline in prison admissions among Black Americans with no college education a cause or a consequence of their improving economic prospects?”
Health
The lie that taints perfectionism
‘How to Be Enough’ author on the difference between admiration and acceptance, the power of ‘2 percent kinder,’ and why values should come before rules
Liz Mineo
Harvard Staff Writer
February 7, 2025
6 min read
Perfectionism has a dark side, says Ellen Hendriksen, a clinical psychologist and faculty member at Boston University, in her new book “Ho
‘How to Be Enough’ author on the difference between admiration and acceptance, the power of ‘2 percent kinder,’ and why values should come before rules
Liz Mineo
Harvard Staff Writer
6 min read
Perfectionism has a dark side, says Ellen Hendriksen, a clinical psychologist and faculty member at Boston University, in her new book “How to Be Enough: Self-Acceptance for Self-Critics and Perfectionists.” In this edited conversation with the Gazette, Hendriksen, whose résumé includes a fellowship at Harvard Medical School, shares her insights on how to roll back tendencies that can lead to painful patterns of self-criticism and isolation.
When is perfectionism a healthy personality trait?
Perfectionism has a healthy heart because its core is conscientiousness, which is the tendency to be responsible and diligent, to do things well and thoroughly, to care deeply. Research has shown that conscientiousness is the No. 1 trait for both objective and subjective success in life. Those of us with perfectionist traits are often highly accomplished. It might manifest as excellent academics, job performance, sports, music, or things that we don’t usually think of as performance, like healthy eating, keeping our space organized, or always looking put together.
How can perfectionism become unhealthy?
Unhealthy perfectionism encompasses over-evaluation, which is the conflation of worth and performance, and harsh self-criticism. It is also unhealthy when we strive to be perfect to try to earn belonging and acceptance. Perfectionism tells us a lie: that we can connect, belong, and be accepted by being good at things through performance. But it backfires because when we perform superbly, we might earn admiration, but that’s different than acceptance. When we’re admired, we’re put on a pedestal, but that means we’re alone.
According to the work of Roz Shafran, Zafra Cooper, and Christopher Fairburn, clinical perfectionism is when our self-worth is dependent on striving to meet personally demanding standards, and we evaluate whether or not we’ve reached those standards in an all-or-nothing way. And if we define failure as not meeting standards, ours or those of others, what will often happen is that we either get overwhelmed or intimidated, and we then avoid our task. Or we’ll try, but we’ll fail, not because we were incapable but because our standards were unrealistic. Either way, self-criticism comes in and leaves us feeling inadequate or not good enough. On the off chance that we pull out all the stops and reach our standards, we’ll decide that our standards were not demanding enough in the first place, and the cycle begins again.
What other manifestations of perfectionism can be problematic?
It also can manifest as a focus on rules, or as a preoccupation with mistakes — either trying to avoid future mistakes or criticizing ourselves for past mistakes. It can also manifest as procrastination because the prospect of meeting our unrealistic standards can be paralyzing. It manifests as social comparison; we’re trying to answer the question, “Am I good enough?” Finally, it manifests as feeling distant or isolated in relationships because we engage in what’s called perfectionistic self-presentation, where we talk about what’s going well and hide what’s going poorly, which makes us come off not only as performative but also unrelatable.
“When we perform superbly, we might earn admiration, but that’s different than acceptance. When we’re admired, we’re put on a pedestal, but that means we’re alone.”
Are there links between perfectionism and depression and anxiety?
If we define failure as not meeting our standards, and these are rigid and unrealistic, we’re going to rack up a lot of failures. Then, repeated over days, years, and potentially decades, we may start to feel like failures. Over time, the two pillars of depression, which are hopelessness (i.e., “This will never get better”) and helplessness (i.e., “Nothing I try works”) settle in.
Regarding anxiety, as we’re struggling with over-evaluation — conflating our performance and our worth — our worth is never a settled question. Every event becomes a referendum on our character: It could be every meeting at work where we expect ourselves to make erudite comments, or exams where we expect ourselves to get an A-plus, or a social event where we expect ourselves to be witty and articulate, or at least not awkward and weird. So, it makes sense that we anticipate every potential performance with trepidation, anxiety, and worry. Forgive my grammar, but it’s when “Did I do good?” means “Am I good? and “I did bad” means “I am bad.”
In your book, you offer specific steps to deal with perfectionism. Can you expand on that advice?
I take the subtitle of the book, “Self-Acceptance for Self-Critics and Perfectionists,” quite literally. By self-acceptance, I mean that we don’t have to change our self-criticism at all. Instead, we can change our relationship to self-criticism. What I suggest is that we can treat our self-critical thoughts like we treat the music at a coffee shop. It’s still there, but we don’t have to sing along. In perfectionism, the heart of which is conscientiousness, we take things seriously, including our own thoughts and feelings. What I suggest is that we can take our self-critical thoughts a little less seriously. We’ll still have them, but we don’t have to treat them as if they are true and literal. We can just let them float by or pass through our mind without getting yanked around.
Another way to overcome perfectionist tendencies is to focus on values rather than rules. Those of us with perfectionist traits like to follow rules, and if there are no rules, we make up personally demanding rules. Values are never coercive, so you freely choose to follow them, and you’re likely willing to tolerate some discomfort to do so. For instance, the value of giving back might mean that you’re willing to give up your Saturday morning to volunteer to pick up trash on the beach rather than spending that morning relaxing at the beach. If we start focusing on values rather than rules, we can choose what is meaningful and important to us rather than following unrealistic rules.
I want to emphasize that becoming less perfectionistic isn’t as laborious as it may appear. Those of us with some perfectionism usually default to gut renovations and total overhauls, but we don’t have to work that hard. Small tweaks are enough. We can aim for being 5 percent more understanding of ourselves, allowing 1 percent mistakes, being 2 percent kinder to ourselves, and that is often enough.
Magda Bader.Photos by Veasey Conway/Harvard Staff Photographer
Nation & World
‘Sorry to see that 80 years later, this is still an important subject’
Christina Pazzanese
Harvard Staff Writer
February 7, 2025
4 min read
Magda Bader was just 14 when the Nazis sent her to Auschwitz. But memory remains clear of losing parents, a sister and her baby, starvation, fear
Magda Bader slipped ou
‘Sorry to see that 80 years later, this is still an important subject’
Christina Pazzanese
Harvard Staff Writer
4 min read
Magda Bader was just 14 when the Nazis sent her to Auschwitz. But memory remains clear of losing parents, a sister and her baby, starvation, fear
Magda Bader slipped out of a packed cattle car at Auschwitz. The 14-year-old lost her grip of her mother’s hand amid the chaotic jostling.
“That’s the last time I saw my mother, my father, and my sister with the baby,” Bader said.
Now 94, Bader recounted in riveting detail the story of her life in a Nazi concentration camp at a JFK Jr. Forum talk Monday evening to mark the 80th anniversary of the liberation of Auschwitz-Birkenau, where an estimated 1 million Jews were murdered by the Nazi regime.
Moderator Mathias Risse, director of the Carr Center for Human Rights Policy at Harvard Kennedy School and Berthold Beitz Professor of Human Rights, Global Affairs and Public Policy, said the conversation was more than simply listening to the recollections of one of the few remaining survivors of the Holocaust.
Mathias Risse (left) and Magda Bader.
“It’s about hearing from somebody who was there, thereby becoming somebody who has heard about it from somebody who was there and can pass on that word down [through] the century,” said Risse.
Bader was living in a small town in Hungary with her parents, four of her sisters, and a baby when the Nazis forced them from their home.
She recalls being marched several kilometers to a vast expanse of concrete where guards in lookout towers fired on people randomly so they wouldn’t try to leave.
For days, the men, women, and children slept outside with no shelter, no bathrooms, and little food before being ordered into cattle cars, jammed in with hundreds of others in the dark, headed to southern Poland.
Once at Auschwitz-Birkenau, Bader, three of her sisters, and all the other prisoners turned over their belongings, including their clothes and shoes, and had their heads shaved.
Surrounded by large walls and electrified fences, the sisters were sent to a single barrack with 1,000 women, mostly Hungarian Jews, where they slept en masse on wood planks. Over time, the sisters, wearing lice-infested clothes and fed only one serving of watery rutabaga soup each day, barely recognized each other, she said. “We had no names anymore, no identification.”
By November 1944, Russian troops were closing in on Auschwitz, so the Nazis rushed to kill or move the remaining prisoners, more than 400,000 Hungarian Jews. Bader and her sisters were sent to a satellite site just outside of Bergen Belsen, a death camp in northern Germany.
Bader’s job was to chop stones outside to use as pavement for the road from the camp barracks to a nearby munitions factory. Just before the British liberated Bergen Belsen in April 1945, the prisoners could hear Allied planes flying overhead at night to bomb the factory.
“We were hoping that maybe the Americans or British would come and save us, but the guards said not to even dream that that will happen,” she recalled. The guards told them they intended to force the prisoners to dig a large ditch before shooting them and dumping their bodies there.
As the Allied forces drew near, the guards fled, creating an opportunity for Bader and her sisters to escape. Dressed in their striped prison dresses, they ran deep into a nearby evergreen forest and hid until the British arrived.
They were treated by the Red Cross and given army uniforms as fresh clothes. Though only 15, Bader was asked to ride with the British Red Cross, serving as an interpreter, while aid workers tended camp survivors.
With no money and no home to return to, Bader and one sister made it out of Germany to England; two other sisters joined them later. After finishing high school, Bader received a scholarship to attend Denver University in Colorado and came to the U.S., where she said she tried to blend in and kept her experience to herself.
“There is so much hate and so much distrust. I wish and I hope that people could learn to live like human beings, with each other, side by side. That’s why I talk to high school kids and college kids. I am sorry to see that 80 years later, this is still an important subject.”
Bader said after all these decades it made her sad to think that her story remains so relevant. “There is so much hate and so much distrust. I wish and I hope that people could learn to live like human beings, with each other, side by side. That’s why I talk to high school kids and college kids. I am sorry to see that 80 years later, this is still an important subject.”
Photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
Origins of Indo-European? Diagnosis bias?
Sy Boles
Harvard Staff Writer
February 6, 2025
1 min read
Have you been paying attention? Test your knowledge of this week's Gazette in our news quiz.
Primary care shortage. New context for history. An extraordinary gift. What do you remember from this week at Harvard?
Science & Tech
Even Bill Gates thinks AI is a little scary
Tech pioneer visits campus with his new memoir to discuss beauty of math, dropping out of College, founding Microsoft, value of curiosity
Christy DeSmith
Harvard Staff Writer
February 6, 2025
5 min read
Photos by Veasey Conway/Harvard Staff Photographer
Bill Gates remembers being “a tough kid.”
“Some teachers wanted to put
Tech pioneer visits campus with his new memoir to discuss beauty of math, dropping out of College, founding Microsoft, value of curiosity
Christy DeSmith
Harvard Staff Writer
5 min read
Photos by Veasey Conway/Harvard Staff Photographer
Bill Gates remembers being “a tough kid.”
“Some teachers wanted to put me ahead in school; some wanted to put me behind,” said the tech pioneer, who has noted in the past that he would likely be diagnosed on the autism spectrum if growing up today. “I exercised my IQ to give my parents a hard time.”
This self-assessment was shared Monday during a campus event marking the release of “Source Code,” Gates’ fifth book and first memoir. The new work charts the billionaire philanthropist’s suburban Seattle childhood and early successes with computer programming through the infancy of Microsoft, the software giant he co-founded in 1975.
Harvard Kennedy School professor Arthur C. Brooks opened the conversation by asking what Gates hoped readers would take from the book. Gates, 69, said he hoped readers would emerge with new ideas about “curiosity and trying out new things — letting kids take risks.”
He touched on the impact of his parents, emphasizing an “intense” relationship with his achievement-oriented mother, Mary. But in the end, Gates gave them credit for allowing a precocious son to experiment in the brave new world of personal computing.
Gates stepped down as Microsoft CEO in 2000 and as chair in 2014. Today he is a high-profile supporter of global initiatives in health, agriculture, development, and education, including the annual Gates Scholarship in the U.S. for outstanding students from low-income families.
“Source Code” returns him to the simpler days of college life. Gates landed on campus in the fall of 1973, more than 10 years before Harvard offered an undergraduate degree in computer science.
Microsoft co-founder Bill Gates (left) speaks at Sanders Theatre with moderator Arthur Brooks.
By then, he had years of experience writing code for the emergent world of personal computers, unleashed by California-based Intel with the 1971 debut of its thumbnail-sized 4004 microprocessor.
But Gates initially rebuffed any suggestion of taking computer-related coursework, as he relayed during a recent visit with current Currier House residents.
“It’s too easy,” he remembered telling friends.
He writes memorably of the way he idolized pure mathematicians — “the beautiful minds on the cutting edge” — and recounts tackling the notorious Math 55A and 55B sequence in advanced calculus, where he was met with academic rigor as well as the math whizzes-turned-College buddies Andy Braiterman and Jim Sethna, both ’77.
The course proved nothing short of humbling.
“For most of my school life I had viewed math as the purest area of intellect,” he writes. “In the bigger pool of Harvard, as obvious as it sounds now, I realized that despite my innate talent, there were people better than me. And two of them were best friends.”
“In the bigger pool of Harvard, as obvious as it sounds now, I realized that despite my innate talent, there were people better than me. And two of them were best friends.”
Despite a few blows to his self-confidence, Gates’ faith in the promise of microcomputing never wavered through two and a half years at Harvard. All along, he and his high-school pal, the late Microsoft co-founder Paul Allen, kept their sights on launching a company together.
“He wanted to do hardware; I wanted to do software,” Gates recalled Monday.
A turning point came during Gates’ sophomore year. Allen was working in Boston as a low-level programmer at Honeywell by then. One snowy afternoon, just before holiday break, Allen burst into the room Gates shared with Braiterman at Currier House. Allen had run straight to the Quad from the now-closed Out of Town News kiosk near the Harvard Square T stop.
In Allen’s hands was the January 1975 issue of Popular Electronics, with a giant photo of the Altair 8800 on its cover.
“He had bought this magazine with the very first personal computer on its cover,” Gates recalled. “It was a cold Boston winter, and he said, ‘Here we are freezing to death, and the revolution has happened without us.’”
Gates would drop out of Harvard that year to start Microsoft, and five years later the company would sign a contract with IBM to write the operating system for its first PC. The firm would go on to develop popular applications, including Word, Excel, and PowerPoint.
A sea of hands waved in the air as students vied to pose questions. A recurring theme involved concerns over the current state of technology, with Gates ringing a note of nostalgia for the techno-optimism of an earlier era.
“When we did things like Microsoft Word, nobody said, ‘Oh, no! People are going to use it to write kidnap notices or incorrect documents,’” he said. “They understood it was a productivity tool that would, by and large, be a very good thing.”
“Do you have concerns about the extent to which technology has utterly taken over the lives of young people?” Brooks asked the father of three.
Anything can be taken to excess, Gates answered, noting that bookish kids were once said to linger in libraries too long. He went on to volunteer that only his youngest daughter came of age during the social networking era, and she wasn’t allowed a smartphone until age 15.
“People always thought that’s weird — the guy who helped birth some of this stuff was trying to keep his daughter from becoming an over-user,” he said.
Late in the event a student stood to solicit Gates’ thoughts on the hot-button topic of where artificial intelligence is headed.
Gates predicted, with signature buoyancy, that the “free intelligence” of AI would soon ease shortages in medicine, teaching, and more. But he conceded the technology was “a little bit scary,” given the speed of its progress.
The parade fêting Hasty Pudding Woman of the Year Cynthia Erivo rolls through Harvard Square on Wednesday.Veasey Conway/Harvard Staff Photographer
Campus & Community
A ‘Wicked’ good time
Nikki Rojas
Harvard Staff Writer
February 6, 2025
3 min read
Actor, singer Cynthia Erivo celebrated as Hasty’s 2025 Woman of the Year
Cynthia Erivo braved frigid weather in a parade through Harvard S
Actor, singer Cynthia Erivo celebrated as Hasty’s 2025 Woman of the Year
Cynthia Erivo braved frigid weather in a parade through Harvard Square on Wednesday as she was honored as Hasty Pudding’s 2025 Woman of the Year. Later the Grammy, Emmy, and Tony Award-winning actor and singer finger-painted and belted out “Defying Gravity” during the theatrical group’s annual roast at Farkas Hall.
Erivo, who captivated movie audiences last year in her role as Elphaba in “Wicked,” was celebrated before previewing Hasty’s 176th production, “101 Damnations.” Hasty Pudding producers Willow Woodward and Daisy Nussbaum, both ’26, co-hosted the roast, which poked fun at Erivo’s close relationship to her “Wicked” co-star Ariana Grande.
The British actor was joined by “Finn Finger Painter” to make a painting for Grande in front of 200 of her “closest friends who have all paid to be here.” To help her along, the theatrical group brought out their own Ariana.
Proving to the audience that she was the “real Wicked Witch of the West,” Erivo delivered an electrifying rendition of “Defying Gravity” from the “Wicked” soundtrack.
Erivo kisses her Pudding Pot.
Niles Singer/Harvard Staff Photographer
Is a good sport as her friendship with “Wicked” co-star Ariana Grande gets roasted.
Niles Singer/Harvard Staff Photographer
Finds herself serenaded by The Harvard Krokodiloes.
Stephanie Mitchell/Harvard Staff Photographer
Shares a laugh with decked-out Hasty Pudding Theatricals cast members.
Veasey Conway/Harvard Staff Photographer
And hoists her prize.
Niles Singer/Harvard Staff Photographer
Following the roast, Erivo said music and song play an important role when developing her characters. “I love when you can combine both song and acting together because I think you get a bit more insight into who the person is, whether it be the way the melody is written or where the rhythm is written,” she said. “It tells you what they’re feeling on the inside about themselves and about the situation that they’re in.”
Erivo also reflected on her work in theater and film, noting that there is “something thrilling about the way you have to use your mind and your body to work your way around” things that happen on stage. After spending a long time embodying characters on screen, she said, she laments having to step away from them.
The actor, also known for her work in “The Color Purple” and “Harriet,” will reprise her critically acclaimed role as Elphaba in the sequel to “Wicked” later this year. “I don’t know that any of us could have expected what has happened with ‘Wicked,’” she said. “We knew it was special, but for the world to take it as its own this way has been really wonderful to behold. I hope that there’s more room for that, for the second one. We haven’t even really got halfway through the story, and to feel like this now is really wonderful.”
Erivo teased that audiences may soon see her in something that feels more “comedic.” She currently has five upcoming works that have been publicly announced, including an adaptation of the popular young adult novel “Children of Blood and Bone.”
Hasty Pudding honored the 2025 Man of the Year, Jon Hamm, with a roast and parade on Jan. 31.
Science & Tech
What prompts genetic adaptation? Ask a finch.
Bohao Fang holding a house finch during a field study trip in Kirtland, New Mexico.Photo by Kelsie Lopez
Clea Simon
Harvard Correspondent
February 6, 2025
4 min read
Groundbreaking pangenomic study suggests big DNA flip may have made small bird resistant to some diseases
Could a novel approach to genetic studies give us a c
Bohao Fang holding a house finch during a field study trip in Kirtland, New Mexico.
Photo by Kelsie Lopez
Clea Simon
Harvard Correspondent
4 min read
Groundbreaking pangenomic study suggests big DNA flip may have made small bird resistant to some diseases
Could a novel approach to genetic studies give us a clearer picture of how evolutionary adaptations occur? That’s what the findings of new research on a common backyard bird, the house finch, imply. A groundbreaking pangenomic study has revealed a major DNA flip that appears to have made the small bird resistant to certain diseases.
“Traditionally people study the genetic variation in a single base pair [of DNA],” explained Fang, a researcher in the Edwards lab. While earlier studies had focused on specific genes in the hope of deciphering what Fang calls “the heritable genetic mechanism underlying disease resistance,” the narrower focus of these studies offered no clear results. However, by studying a broader stretch of DNA, “We find the long-read sequencing that can help us catch important large-scale structural variations that otherwise might be missed.”
In the house finch, this new approach revealed a DNA inversion that has existed for millions of years — and that may have helped the bird fight off infection.
“This gives us a better picture about how in the wild, without vaccines, evolution can respond to new diseases.”
Bohao Fang
“The house finch is a really great model to study a coevolution of a host and a disease,” said Fang. This project, he said, began in the wake of the COVID-19 pandemic, when he became interested in the development of natural resistance to widespread diseases. The house finch and its reaction to a conjunctivitis-causing bacterial pathogen that spread across the U.S. beginning in 1994 provided a good example. The Museum of Comparative Zoology had maintained sequenced house finch DNA samples dating back to 2000, giving Fang “a really great resource” for research.
This large pool allowed Fang to “read the big picture in the DNA and see how this wild bird responded evolutionarily to this disease.” By studying genetic material collected over time — both before and after an epizootic — “You can see how it evolved to develop some immunity to this disease.
“This gives us a better picture about how in the wild, without vaccines, evolution can respond to new diseases.”
Although more research needs to be done, Fang said, this study shows how a structural variant — that is, a large DNA change — “might potentially be contributing this kind of adaptive evolution to fight the disease.”
“These offer a really great real-life example of how a species deals with a new pathogen,” Fang explained. “This also gives us clues about how other animals, even humans, might genetically respond to the infectious disease over time.”
“Bohao’s work really points the way to the future of population genomic studies in birds, and in other natural populations generally. The pangenome approaches that he used provide a better — and more balanced — representation of genetic variation within a species,” said Scott V. Edwards, professor of organismal and evolutionary biology, curator of ornithology, Alexander Agassiz Professor of Zoology in the MCZ, and the co-author on the study.
“By not using just a single reference individual to score variation of the whole population, the pangenome approach not only is much less biased but will also make it easier for scientists studying wild animals to make new discoveries. The large inversion that Bohao found was correlated with pathogen prevalence in the house finches that would have been invisible to us without these new approaches.”
Nation & World
Danger ahead
In advance of his lecture at Harvard Thursday, former national security official Ben Rhodes spoke to the Gazette about global trade, hotspots including Syria and Gaza, and the state of U.S. relations with China, Russia, and other nations.AP photos by Deccio Serrano (from left), Maxim Shipenkov, Omar Albam, and Mohammad Abu Samra; photo illustration by Liz Zonarich/Harvard Staff
Christina Pazzanese
Harvard
In advance of his lecture at Harvard Thursday, former national security official Ben Rhodes spoke to the Gazette about global trade, hotspots including Syria and Gaza, and the state of U.S. relations with China, Russia, and other nations.
AP photos by Deccio Serrano (from left), Maxim Shipenkov, Omar Albam, and Mohammad Abu Samra; photo illustration by Liz Zonarich/Harvard Staff
Christina Pazzanese
Harvard Staff Writer
8 min read
Former national security official surveys hot spots in Middle East, Asia, Eastern Europe — and how new president’s ideas are being received
Last year was a tumultuous one: conflicts in Gaza, Ukraine, Lebanon, and Sudan; the ouster of Syria’s Bashar al-Assad; increasing tension between Israel and Iran, and China and the U.S. and Taiwan; and a record 4 billion voters who ousted incumbent leaders in numerous countries. What’s in store for 2025?
In this edited Jan. 27 conversation, Ben Rhodes, former deputy national security adviser and speechwriter to President Barack Obama, discusses what may lie ahead in key global hotspots and how other countries are reacting to some new foreign policy ideas floated by President Donald Trump. Rhodes, who spoke to the Gazette before Trump’s Feb. 4 meeting with Israeli Prime Minister Benjamin Netanyanhu, will deliver the Warren and Anita Manshel Lecture in American Foreign Policy on Thursday.
Given the current state of upheaval around the globe, what would you flag as top concerns if you were advising the president on national security today?
I guess there are two things I would point to: We’re in this period where there is no longer the international order that governed geopolitics for the last several decades, and there is a normalization of conflict happening.
When you look at Ukraine, at the Middle East, and Taiwan, the possibility of great power conflict feels uncomfortably high right now. You have a return to a pre-World War I absence of rules, large countries ignoring norms and getting comfortable with territorial conquest without mechanisms to resolve conflicts because the system isn’t working anymore. And so, the first thing is to take seriously the risk of escalating global conflict.
The second thing are structural issues: climate, artificial intelligence, and nuclear weapons once again. We seem to be headed in a direction of a new nuclear arms race, an absence of rules around the proliferation of artificial intelligence, which is going to create all kinds of risks, and an absence of coordinated effort on climate. Those things are connected. In the absence of diplomacy and great working power relations, both the ability to stop conflict and avoid it and to address the defining issues is currently absent. And that, to me, is the biggest risk.
U.N. Secretary-General António Guterres recently said the Middle East “is in a period of profound transition, rife with uncertainty but also possibility.” What may be on the horizon?
There’s some promising developments. The removal of Assad, obviously, is a very positive development that creates an opening for Syria and Lebanon to have a better future. You have the Gulf states, not just in their relations, but in their autocratic prosperity model, trying to bring about a paradigm of stability and interconnection with the rest of the world.
But I just think you have massive challenges remaining. In addition to the Palestinians, one of the underappreciated risks right now is how brittle the governments are in Egypt and Jordan in a way that I feel some echoes of the pre-Arab Spring times. In Egypt, you have a very unpopular and corrupt military government and a very dissatisfied, if not angry, population. And in Jordan, you have a perennially somewhat-vulnerable monarchy with a large Palestinian population. And so, there’s the potential for surprises in the Middle East beyond what is already happening.
And then, of course, you have the unresolved question of Iran. Yes, Iran is weakened, but to what end when you consider the nuclear program? Does that lead you in the direction of trying to make a diplomatic agreement along the lines of what we did in the 2015 nuclear deal, or does that lead to the potential for a military conflict involving the United States and Iran?
The new administration has to determine whether they are going to pursue a regime-change type approach toward Iran or a military option related to the nuclear program, given how far advanced it is, or are they going to try to resolve that issue diplomatically, thinking they have a stronger hand to play? As clear as Trump has been on a lot of things the last few days, that remains kind of an open question.
“You have a return to a pre-World War I absence of rules, large countries ignoring norms and getting comfortable with territorial conquest.”
Russian President Vladimir Putin and Trump have signaled they may have an interest in a broader discussion that would include Ukraine but also nuclear arms control and lifting sanctions, according to The New York Times. If accurate, what might that all mean?
Putin would definitely want to enlarge the agenda because he sees Ukraine as connected to this larger conflict with the United States, from the future of NATO to nuclear arms control to the sanctions on the Russian economy. So, Putin has a lot of interest in enlarging that agenda.
It wouldn’t surprise me if Trump is inclined to do that because Trump is less viscerally focused on Ukrainian sovereignty and the right and wrong of the conflict. I don’t even mean that as a criticism: If you take Trump’s transactional worldview, Ukraine is more like a piece of a larger puzzle.
The Biden team did not accept this premise of seeing Ukraine in a bigger context, because to them, it was about the right and wrong of what Russia was doing in Ukraine. But ultimately, that’s the reality, and if it’s easier to make progress in a negotiation that might include some benefit to Ukraine by enlarging the agenda, it’s worth testing. I’m always in favor of diplomacy, or at least exploring it. But we have to be realistic that that may not work unless Trump is willing to trade away things past presidents weren’t willing to trade away in the U.S.-Russia relationship.
U.S.-China relations ran hot and cold during Trump’s first term. Now, with Trump’s willingness to resolve the TikTok ban but also increasing tariffs, the White House is sending more mixed signals. What direction is this relationship headed?
As with the Iran question, this is one where it’s not clear to me exactly where Trump is going to go. He has filled his national security team with people who see us not just in an economic conflict with China, but in a geopolitical and ideological conflict with China.
I took the TikTok ban as an early indication that Trump’s more pragmatic approach is more likely to prevail. TikTok is the ultimate example of an issue that is about ideology and influence, and, to some extent, geopolitics. Trump wasn’t willing to go to the mat on that despite having a piece of legislation that had been passed under the previous administration.
To me, it suggests that he’ll be more focused on the trade piece. I’d expect tariffs; I’d expect a trade war of sorts; but I’m not sure that it’s going to be the Republican Hawk version of a China policy that would have a huge Taiwan focus and be more focused on these ideological questions.
Some of the things Trump is doing are going to help China. Trump’s pivot back to fossil fuels is perfectly aligned with China’s focus on dominating clean energy technologies and supply chains. On AI, as we’ve been seeing, China’s figuring out how to work around all these sanctions and export controls.
If I’m China, what I’m doing in the Trump years is taking advantage of all the things Trump is going to break in Europe, in Africa, and Latin America. There’s more opportunity for China in a Trump presidency than people might see on the surface.
How are allies and adversaries interpreting talk about the U.S. annexing Greenland, the Panama Canal, or Canada?
I think people take the Greenland threat very seriously. I don’t like the idea of returning to territorial expansionism, but there is a credible interest the U.S. has. Greenland is a massive territory; it has enormous natural resources that are going to be more accessible with climate change, and it’s strategically located vis-a-vis Russia and China, to some extent.
Denmark’s hold on that is quite tenuous. So, of the three, Greenland feels like it could become a real source of tension.
The Arctic is incredibly important. It would definitely serve the strategic interest in the United States if Greenland were a part of the United States or a territory of the United States. My concern is that while there’s a lot of strategic interest, the global risk of it being part of a slide toward a larger conflict is real.
Science & Tech
Landmark studies track source of Indo-European languages spoken by 40% of world
Nick Patterson (from left), Iosif Lazaridis, and David Reich. Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
February 5, 2025
6 min read
Researchers place Caucasus Lower Volga people, speakers of ancestor tongue, in today’s Russia about 6,500 years ago
A pair
Landmark studies track source of Indo-European languages spoken by 40% of world
Nick Patterson (from left), Iosif Lazaridis, and David Reich.
Veasey Conway/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
6 min read
Researchers place Caucasus Lower Volga people, speakers of ancestor tongue, in today’s Russia about 6,500 years ago
A pair of landmark studies, published Wednesday in the journal Nature, has finally identified the originators of the Indo-European family of 400-plus languages, spoken today by more than 40 percent of the world’s population.
DNA evidence places them in current-day Russia during the Eneolithic period about 6,500 years ago. These linguistic pioneers were spread from the steppe grasslands along the lower Volga River to the northern foothills of the Caucasus Mountains, with researchers dubbing them the Caucasus Lower Volga people. Genetic results show they mixed with other groups in the region.
“It’s a very early manifestation of some of the cultural traditions that later spread across the steppe,” said senior author David Reich, a professor of genetics at Harvard Medical School and human evolutionary biology in the Faculty of Arts and Sciences.
The research provides the missing piece of a longstanding linguistic puzzle.
Scholars first noted similarities among the far-flung languages of Latin, Greek, and Sanskrit in the late 18th century. The so-called steppe hypothesis, formulated during the 19th century and formalized in the 1950s, postulated that speakers of the ancestor language of the Indo-European group lived on the Eurasian steppe. Scholars drew on linguistic reconstructions and archaeological evidence to place them in an area where Russia and Ukraine stand today.
These nomadic pastoralists were the first to “harvest the bioenergy of the Eurasian grasslands,” explained Anthony, an emeritus professor at Hartwick College in New York. The Yamnaya were probably the first to herd on horseback and early adopters (if not inventors) of oxen-towed wagons.
“I don’t think we can even imagine what it was like for other people to see a wagon coming,” marveled Anthony, a co-lead author of the new research and a 2019-2020 visiting scholar in the Reich laboratory. “It was moving across the landscape, creaking and groaning, pulling a ton of equipment. People had never seen anything like it before.”
With larger herds and superior mobility, the Yamnaya started exporting their economy — and their language — about 5,000 years ago. “They spread from the steppes north of the Black and Caspian seas all the way to Mongolia on one side and as far as Ireland on the other — 6,000 kilometers!” Anthony said.
Nick Patterson, deputy head of Reich’s Harvard-based lab and an associate in the Department of Human Evolutionary Biology (HEB), remembers reading the book and discussing it at a conference a few years following its publication.
“His book contained no genetics at all,” said Patterson, who is also a co-lead author of the new research. “But my genetic results were completely compatible with what he was saying.”
Reich’s lab has been pursuing proto-Indo-European speakers for more than 15 years. In 2014, they shared key insights in a Nature article on what Reich called “the profound mixing event” that shaped modern Europeans, with most descended from three highly differentiated populations.
The following year, the lab’s scientists offered a fuller picture of the continent’s Yamnaya set of ancestors. “They turned over the population of Europe with huge disruptions in Germany, Spain, Italy, Hungary,” Reich explained. “In Britain, there was a 90 percent-plus population replacement within decades.”
The 2015 Nature paper credited the Yamnaya with carrying Indo-European languages across Europe and into the Indian subcontinent. Later papers, published by Reich’s lab and others, followed their genetic footprints into Greece, Armenia, India, and China.
“It’s like a tracer dye,” Reich said. “You can actually see Yamnaya ancestry everywhere these languages went.”
But researchers encountered a hitch within the Yamnaya line in the Anatolian peninsula. An extinct set of Indo-European languages was spoken there during the Bronze Age. Linguists have long believed they represent an early split from proto-Indo-European. During the 21st century, ancient DNA science surfaced similar conclusions.
Genetic reconstruction of the ancestry of Pontic-Caspian steppe and West Asian populations points to four key locations.
“We know people like the Hittites spoke Anatolian from cuneiform tablets,” Reich noted. “But these people didn’t have Yamnaya ancestry. We looked hard, with lots of data. We didn’t find anything. So we hypothesized some deeper population was the ultimate source in Indo-European languages.”
The Caucasus Lower Volga people appear to be that original source, with newly uncovered links to both the Yamnaya and the ancient Indo-Anatolian speakers who inhabited an area that is now part of Turkey. The discovery marks a collaborative triumph that builds upon decades of work by linguists, archaeologists, and geneticists.
“It’s the first time we have a genetic picture unifying all Indo-European languages,” said co-lead author Iosif Lazaridis, a research associate in HEB.
“It’s the first time we have a genetic picture unifying all Indo-European languages.”
Iosif Lazaridis
But the Russia-Ukraine war forced an unusual splintering of the findings. A first paper, focused on the origins of Indo-European languages, draws on the ancient DNA of 354 individuals at archaeological sites in Russia and Southeastern Europe. A second, authored with researchers in Kyiv, is based on 81 ancient DNA samples drawn from Ukraine and Moldova. Also part of the analyses are genetic data on nearly 1,000 previously reported ancient individuals.
“At present it’s very difficult for Ukrainian scholars to co-author with Russians,” Reich said.
The first paper traces various lineages from the Caucasus Lower Volga people, including the Yamnaya and the Anatolians, while samples analyzed for the second provided rich new context on the “Yamna” (the Ukrainian term for Yamnaya). The paper finds evidence that the culture may have taken root somewhere near the small town of Mykhailivka in the southern part of the war-torn country.
“Where the worst of the fighting is happening right now — that’s the Yamnaya homeland,” Anthony said.
What is now clear is that a population of Caucasus Lower Volga people moved west and started mixing with locals, thereby forming the distinct Yamnaya genome.
Co-authors David Anthony, Pavel Kuznetsov, and Oleg Mochalov on a treeless steppe in the Samara River valley in 1995.
Credit: David Anthony, Pavel Kuznetsov, and Oleg Mochalov
“We can see there was a small group of villages 5,700 to 5,300 years ago with just a couple thousand breeding individuals,” Reich said. “And then there was a demographic explosion, with these people going everywhere.”
Language isn’t the only tradition the Yamnaya carried on from their Caucasus Lower Volga forebears. Both cultures buried their dead in kurgans, or large tombs with earth mounded on top. These graves, which still dot the region’s flat landscape, attracted generations of archaeologists and have now enabled “the genetic reconstruction of their makers’ origins presented here,” as Lazaridis wrote in the first paper.
“Suppose the Yamnaya had a different culture,” Patterson offered. “Suppose they had cremated their dead. Chances are, we wouldn’t even know about this crucial culture in human history.”
Some of the research for the papers was supported by the National Institutes of Health and the National Science Foundation.
Martin West.Niles Singer/Harvard Staff Photographer
Nation & World
Turns out pandemic wasn’t only cause for student setbacks
Education policy expert cites chronic absenteeism, easing of test accountability, other issues for poor marks in ‘Nation’s Report Card’
Clea Simon
Harvard Correspondent
February 4, 2025
5 min read
Those who thought public school students were recovering from pan
Turns out pandemic wasn’t only cause for student setbacks
Education policy expert cites chronic absenteeism, easing of test accountability, other issues for poor marks in ‘Nation’s Report Card’
Clea Simon
Harvard Correspondent
5 min read
Those who thought public school students were recovering from pandemic-era setbacks were shocked last week as the National Assessment of Educational Progress (NAEP) — known as the “Nation’s Report Card” — showed that test scores for fourth and eighth graders have continued to decline in reading and bounced back only slightly in math.
That’s because more than the pandemic is to blame, says Martin West, academic dean of the Graduate School of Education, who sits on both the NAEP board and the Massachusetts Board of Elementary and Secondary Education. West, the Henry Lee Shattuck Professor of Education, discussed the Massachusetts and U.S. results — and the other factors at play — in this edited conversation with the Gazette.
Chronic absenteeism, worsened by the pandemic, generally has been blamed for declining scores. Is that what you’re seeing?
Chronic absenteeism more than doubled nationwide amid the pandemic and has been very slow to come down and not yet reached pre-pandemic levels. But I don’t think that’s the entire story because the declines in reading achievement nationally started well before the pandemic, as early as 2015. At this point what we’re seeing is more a consequence of a decade of steady declines in students’ reading comprehension skills rather than the consequence of the pandemic.
What else might be contributing?
There are many possible theories, and unfortunately the national data on their own aren’t able to tell us which is correct. The two candidates that seem most plausible to me are, first, the rise of social media and what some call screen-based childhood in the 2010s and what that has meant for students’ reading habits outside of school. And second, the softening of test-based accountability policies that began around 2010 and has continued through today.
Do you mean testing is to blame?
I don’t think that’s accurate. We still test students annually in grades three through eight and once in high school. That remains a federal requirement. We’ve just given states much more latitude in how they act on the results of those tests, and most states have taken a very hands-off approach. So it’s not that students are taking fewer tests, it’s that we no longer pay a lot of attention to the results.
About two-thirds of white, Asian, and non-economically disadvantaged students scored at or above the “proficient” level on the fourth-grade math test, as compared to about one-quarter of Black, Latino, and economically disadvantaged students in Massachusetts, and a similar disparity was seen in reading scores.Would you discuss this disparity?
We have seen in recent data growing inequality in performance between higher-achieving and lower-achieving students. In the just-released 2024 results, the small gains that students made in fourth grade math were driven primarily by gains among higher-achieving students, while the scores of lower-achieving students were stagnant.
The declines that we saw in reading achievement at both fourth grade and eighth grade were driven primarily by declines for lower-achieving students. This divergence extends a trend that began in the middle of the last decade and has led to much more substantial inequality. And oftentimes that inequality falls along lines of demography like economic disadvantage and race and ethnicity.
In the past, national programs like “No Child Left Behind” have worked to raise test scores for low-achieving students. In Massachusetts, Gov. Maura Healey has announced the state’s Literacy Launch initiative to reverse recent trends.
The Healey administration has devoted considerable resources and political capital toward its Literacy Launch program, and I certainly hope that will be an important step toward a comprehensive approach to improving literacy rates in Massachusetts.
Massachusetts gets to pat itself on the back every two years when the NAEP results come out because it is the highest-achieving state in the nation across all four assessments.
But it’s important to keep in mind that there are two Massachusetts stories in this round of NAEP results. One is the “best in the nation” story. The other is that we continue to have persistent learning loss due to the pandemic and that we have declined substantially from peak achievement levels early in the prior decade.
We have also not been immune from this phenomenon of increasing inequality between higher-achieving and lower-achieving students. In fact, the achievement gaps associated with economic disadvantage in Massachusetts are as large or larger as those seen anywhere in the nation.
The patterns we see for Massachusetts in the 2024 results roughly mirror what we see for the nation as a whole. Students demonstrated some progress toward recovery from pandemic learning loss in fourth grade math. They did not make any progress toward recovery in eighth-grade math, where they had experienced even larger declines.
And although reading scores in Massachusetts were officially unchanged because they were not statistically distinguishable from the level that we saw in 2022, they did trend downward in a manner consistent with what we saw nationwide.
Can you explain the slight rebound in fourth-grade math scores? Why might we see a recovery in math alongside continued declines in reading?
We often find that math achievement is more sensitive to what students experience in school — the amount of instructional time, the quality of the curriculum and pedagogy — than is reading achievement, which is more heavily influenced by all that students experience in their lives outside of school. That could explain why we see recovery efforts translating into quicker progress in math than in reading.
Edvard Munch prints, paintings gifted to Harvard Art Museums
Works will go on display in March exhibition, examining the artist’s experimental printmaking and painting techniques
Harvard Art Museums Communications
7 min read
An extraordinary gift of 62 prints and two paintings by Edvard Munch, as well as one print by Jasper Johns, from the collection of Philip A. ’37 and Lynn G. Straus was announced by Harvard Art Museums on Tuesday.
The bequest is a final act of generosity from the Strauses following a relationship with the museums that began in the 1980s and that includes multiple gifts of artworks over the years; the support of a 1990s-era expansion, renovation, and endowment of the museums’ conservation center; and the endowment of specific conservation and curatorial positions.
The works by Norwegian artist Edvard Munch (1863–1944) in the Strauses’ bequest join an important concentration of paintings and prints by the artist already at Harvard and build upon multiple past gifts and assisted purchases of Munch’s work by the couple — 117 works altogether. The total number of works by the artist in the Harvard Art Museums’ collections is now 142 (eight paintings and 134 prints), constituting one of the largest and most significant collections of works by Munch in the U.S.
The Strauses have been among the Harvard Art Museums’ most generous benefactors. In 1969, the couple purchased their first print by Munch, “Salome” (1903), an acquisition that marked the start of their passion for the artist’s work. Following a commitment to a $7.5 million gift in 1994, the museums’ conservation center — the oldest fine arts conservation treatment, research, and training facility in the U.S. — was renamed the Straus Center for Conservation and Technical Studies. Philip, a New York investment adviser and portfolio manager, passed away in 2004, and their bequest comes to Harvard following Lynn’s passing in 2023. In total, the couple gifted or enabled purchases of 128 works to the Harvard Art Museums over their lifetimes, including works by Max Beckmann, Georges Braque, Alexander Calder, Timothy David Mayhew, and Emil Nolde.
Edvard Munch, “Two Human Beings (The Lonely Ones),” (1906–8). Oil on canvas.
Busch-Reisinger Museum, The Philip and Lynn Straus Collection, 2023.551.
“Two Human Beings (The Lonely Ones)” (1899). Woodcut printed on tan wove paper.
Fogg Museum, The Philip and Lynn Straus Collection, 2023.602.
“Train Smoke” (1910) is a landscape unlike those by Munch already in the collection.
“We are immensely grateful to Philip and Lynn Straus for their generosity and stewardship over these many years,” said Sarah Ganz Blythe, the Elizabeth and John Moors Cabot Director of the Harvard Art Museums. “Their enthusiasm for the work of Edvard Munch ensures generations of students and visitors can experience and study his prints and paintings here in Cambridge. Through their distinct style of collecting Munch’s prints — seeking out and acquiring multiple images of the same theme — they created a collection that affords deep insights into the artist’s practice and is therefore a perfect match for a university museum with a strong teaching and research mission.”
Ganz Blythe continued: “Their support of the conservators and conservation scientists in the Straus Center has had a transformative impact on the numerous fellows who have trained there, as well as provided a facility where every object in our collections can be cared for and scientifically researched.”
The Strauses’ recent bequest includes Munch’s iconic painting “Two Human Beings (The Lonely Ones)” (1906–8) and “Train Smoke” (1910), both of which are now in the collection of the Busch-Reisinger Museum, one of the Harvard Art Museums’ three constituent museums. These paintings join “Winter in Kragerø” (1915) and “Inger in a Red Dress” (1896), previously given to the museum by Lynn in memory of Philip in 2012.
Philip and Lynn Straus with their first Edvard Munch print, “Salome” (1903), c. 1969.
Courtesy Philip A. Straus Jr.
In “Two Human Beings (The Lonely Ones),” a man and woman stand side by side yet still feel isolated from one another, facing toward the sea and away from the viewer, each embedded in a colorfully sedimented landscape. Munch first painted this subject around 1892 and returned to it repeatedly in his printmaking and painting thereafter. “Train Smoke,” which depicts nature disrupted but also dynamically animated by the Industrial Revolution, is a landscape unlike those by Munch already in the collection. Both paintings demonstrate Munch’s experimentation with color and surface texture, through his varied use of thick impasto, diluted paint drips, and even areas of bare canvas, a hallmark of Munch’s artistic legacy.
“It is hard to overestimate the significance of Munch’s painting ‘Two Human Beings (The Lonely Ones).’ Capturing the tension between proximity and distance — spatial as well as emotional — the work addresses the universal theme of the human condition,” said Lynette Roth, the Daimler Curator of the Busch-Reisinger Museum at the Harvard Art Museums. “The Strauses had generously loaned their painting for the inaugural installation of the renovated Harvard Art Museums building that opened in November 2014, and we are thrilled to be able to teach with and display it alongside the other significant paintings from their collection going forward.”
Over the course of 2024, both paintings have undergone cleaning and other treatments by Kate Smith, senior conservator of paintings and head of the Paintings Lab, and Ellen Davis, associate paintings conservator, both in the museums’ Straus Center. “Two Human Beings (The Lonely Ones)” had been varnished at some point in its history, which is not consistent with Munch’s practice of leaving his canvases without a unified glossy surface. “Train Smoke” needed paint stabilization and cleaning to remove atmospheric grime. After careful study, removal of the varnish and grime from the paint surface, and treatment of small areas of paint loss, the paintings are now in closer alignment with their original appearance.
The 62 prints in the Strauses’ recent bequest have entered the collection of the Fogg Museum. The majority are highly prized impressions that Munch exhibited in his lifetime, and they speak to the aesthetic he preferred for the display of his prints: Some of the impressions are cut to the image, and adhered to larger, heavy brown paper, which Munch signed and often dated. Also included are multiple states of single compositions. They showcase the range of techniques the artist used in his printmaking practice: drypoint, etching, lithography, mezzotint, and woodcut, and innovations through the addition of hand-applied color such as watercolor, crayon, and oil, or printing with woodblocks sawn into pieces.
“With this bequest, the Harvard Art Museums have become an important destination for the research of Munch’s prints,” said Elizabeth M. Rudy, the Carl A. Weyerhaeuser Curator of Prints at the Harvard Art Museums. “There are innumerable ways the collection offers opportunities for teaching, exhibition, and further study. Noteworthy for its groups of versions, states, and variations of single compositions, this collection offers wide-ranging insights into Munch’s innovative practice as a printmaker.”
The Jasper Johns print included in the bequest, “Savarin” (1982), is a lithograph and monotype; it depicts a Savarin-brand coffee can filled with paintbrushes of various sizes. The backdrop incorporates the artist’s signature “crosshatch” work of the 1970s, which is represented in other prints by Johns in the museums’ collections. The arm shown at the bottom of the print is a reference to the skeletal arm shown in Munch’s “Self-Portrait” from 1895 — a connection the couple noted by hanging the two prints near each other in their own home.
Visitors are welcome to view the prints and paintings, by appointment, in the Harvard Art Museums’ Art Study Center. The special exhibition “Edvard Munch: Technically Speaking,” on display March 7 to July 27 at the Harvard Art Museums, will include many of the works from the Strauses’ recent bequest as well as from prior gifts. The exhibition will showcase roughly 70 works, with key loans from the Munchmuseet in Oslo, Norway, and will include examples of the artist’s materials used for printmaking.
Nation & World
‘We cannot let our past become our children’s future’
Former Harvard President Larry Bacow joined world leaders, delegates, and survivors at a Jan. 27 ceremony marking the 80th anniversary of the liberation of Auschwitz.
Liz Mineo
Harvard Staff Writer
February 4, 2025
8 min read
Larry Bacow, whose mother survived Auschwitz, represents University at ceremony marking 80th annivers
‘We cannot let our past become our children’s future’
Former Harvard President Larry Bacow joined world leaders, delegates, and survivors at a Jan. 27 ceremony marking the 80th anniversary of the liberation of Auschwitz.
Liz Mineo
Harvard Staff Writer
8 min read
Larry Bacow, whose mother survived Auschwitz, represents University at ceremony marking 80th anniversary of death camp’s liberation
Larry Bacow’s mother, Ruth Wertheim, was 15 when she was sent to Theresienstadt concentration camp in the Czech Republic. Two years later, she was sent to Auschwitz, where she was separated from her parents, and subsequently moved to Merzdorf in Germany. Wertheim, the only member of her family to survive the war, was 18 when her camp and Auschwitz were liberated in 1945. A year later, she came to the U.S.
Former Harvard President Bacow joined world leaders, official delegates, and survivors on Jan. 27 as a representative of the University in a solemn ceremony commemorating the 80th anniversary of the liberation of Auschwitz in southern Poland. The site, where the Nazis murdered nearly 1 million Jews, has become an enduring symbol of the Holocaust and is now a museum and memorial.
In this edited conversation with the Gazette, Bacow spoke about the event, his first visit to the Auschwitz complex.
Can you tell us about your family’s connections to the Holocaust?
My mother was the only member of her family and the only Jew from her town, Londorf, Germany, who survived the war. I never really talked much about my mother in my professional life until I became president of Harvard in 2018. That was a time in which the government was showing increasing hostility toward immigrants as well as refugees, and I thought it was important for people to understand that those who come to this country from abroad typically do so for a variety of reasons.
One is simply to seek a better life for themselves and their children. They also come in search of religious freedom, and they may not have much in the way of resources. They may not speak the language, but they have a fierce determination to provide a better life for their children than they would have if they had remained behind.
Both of my parents were refugees. My father was born in Minsk in Belarus, and he came before the war, but my mother came after the war, so I started talking about it.
“How could she have lived through this experience and not been totally traumatized by it?”
Larry Bacow: “I once asked her, ‘How could she have lived through this experience and not been totally traumatized by it?’ She was 15 when she went into the camps, 18 when she was liberated. She said, ‘At that point, Hitler had taken from me everything that I cared about: my parents, my friends, my entire family, our home, our possessions.’ She said, ‘I could have been angry or bitter for the rest of my life, and Hitler then would have deprived me of everything else, or I could live well, and that would be my revenge.’ And that was my mother. She was an amazingly resilient and strong person.”
Was this your first time in Auschwitz?
Yes. I had avoided going to any of the death camps previously. It was too close. My earliest memory as a child is my mother waking up in the middle of the night with a nightmare. I was 4 years old, and she was only nine years out of Auschwitz.
Having said that, my mother was a really remarkable woman, because first of all, she was very optimistic, determined, and forward-thinking; she was everyone’s favorite aunt. Everybody loved my mother. I once asked her, “How could she have lived through this experience and not been totally traumatized by it?” She was 15 when she went into the camps, 18 when she was liberated.
She said, “At that point, Hitler had taken from me everything that I cared about: my parents, my friends, my entire family, our home, our possessions.” She said, “I could have been angry or bitter for the rest of my life, and Hitler then would have deprived me of everything else, or I could live well, and that would be my revenge.” And that was my mother. She was an amazingly resilient and strong person.
How did the ceremony affect you personally?
When Alan Garber invited me to represent Harvard at the 80th anniversary of the liberation of Auschwitz, I thought this was something that I needed to do. In some ways, it was an opportunity to physically bear witness to the atrocities that had been inflicted upon my mother and her family, and so many others.
What made the trip particularly poignant is that Auschwitz was liberated on Jan. 27 of 1945, and my mother passed away on Jan. 27, 1994, so this was the anniversary of my mother’s death. I just felt like I had to do this. This was important, especially at a time in which antisemitism is rising throughout the world. I was with two dozen heads of state who attended and other delegates who were there to make a statement that this should not and cannot happen again.
In 2022, Bacow attended a Holocaust memorial in Londorf, Germany, the hometown of his mother, Ruth Wertheim. Her photo is on display, center right.
File photo by Stephanie Mitchell/Harvard Staff Photographer
What were the most moving aspects of the ceremony for you?
There are commemorative events every five years. At this year’s commemoration the only speakers were Auschwitz survivors. This being the 80th anniversary, the organizers recognized that five or 10 years from now, there are likely to be no remaining survivors. The focus of the event was on the testimony of survivors. They were the only ones who spoke, other than the heads of the foundation and the museum, each of whom gave brief remarks.
Each of the survivors was quite elderly, in many cases quite frail, and some were using walkers and canes. They needed to be assisted to get to the podium, but that made their testimony that much more powerful — that they were determined for the world to know what happened and what happened to them. There’s a quotation that’s often attributed to Stalin, “The death of one man is a tragedy, the death of millions is a statistic.” Hearing the survivors’ stories made a number that’s otherwise incomprehensible very, very real. It was extremely, extremely moving.
There were also a few additional poignant moments. We all took shuttle buses from a parking lot to get to the event. It wasn’t a long trip, maybe eight or nine minutes. The buses were quite crowded, with most people standing, and as the buses drove in, we passed a cattle car in part of the preservation area in Auschwitz. I couldn’t help but think: Here we were in a bus that had heat, and although we were closely packed, it was nothing in comparison to those in which people who were deported to Auschwitz faced. There were hundreds of people crammed into these cattle cars, in many cases, without food or water, or even space to lie down.
I was also struck at the end of the ceremony, when we all rose to be led in prayer. There’s a prayer called Kaddish that Jews say for loved ones who have died on the anniversary of their death. This was the anniversary of my mother’s death, and saying it there, where the ashes of her family were literally scattered, was something I will never forget for the rest of my life.
“Hearing the survivors’ stories made a number that’s otherwise incomprehensible very, very real.”
My mother talked about how she was separated from her parents as they went directly to the crematorium. I was also impressed by the commitment of those who had worked so hard to preserve this memory and to preserve Auschwitz itself. They were not Jews. They were Poles. I think they are to be commended for their good efforts.
What role can universities play in preserving the memory of the Holocaust?
Our motto is truth, Veritas, and this is a time in which people continue to deny the existence of the Holocaust, where major leaders suggest that the time has come to turn the page and stop focusing on what the Nazis did.
It’s in these times that universities have a role to play by helping to preserve the record and to teach what actually happened. There were many Holocaust scholars who were represented at the event. Ronald Lauder, who is the chairman of the Auschwitz-Birkenau Memorial Foundation, pointed out that five years ago, at the last commemorative event, it was unthinkable that the world could be awash in antisemitism as it is now.
He said, “All the more reason to capture these stories, to document them, to preserve Auschwitz for posterity.” The entire Auschwitz death camp is preserved as a museum, and the Polish people deserve enormous respect for having done that.
There was one speaker who quoted a survivor who had spoken at the 70th anniversary of the commemoration of Auschwitz, someone by the name of Roman Kent, a Polish Holocaust survivor who is no longer alive. Kent’s quote really captured the purpose of the event. He said, “We cannot let our past become our children’s future.” For me, that sums things up quite well.
Campus & Community
A family at School when home is far away
First-year Emmanuel Muriuki (left) and Sheila Thimba, dean of administration and finance.Veasey Conway/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
February 3, 2025
7 min read
Program has connected affiliates, new international students for more than 40 years
Every Thanksgiving, a handful of international Co
First-year Emmanuel Muriuki (left) and Sheila Thimba, dean of administration and finance.
Veasey Conway/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
7 min read
Program has connected affiliates, new international students for more than 40 years
Every Thanksgiving, a handful of international College students trek to Diane Gallagher’s house in Brookline to eat home-cooked turkey, mashed potatoes, and gravy, and to share the history of their home countries’ flags.
Isa Salmanu ’28 from Nigeria was part of the group this past November, along with classmates from Argentina, Honduras, Portugal, and Spain. “The table was lively and full, as Diane had invited her neighbors and children. It felt like a big, warm gathering,” the Pennypacker Hall resident said. “We talked about a little bit of everything.”
The tradition is one of many that Gallagher and her two daughters have maintained since she became one of the inaugural members of the Harvard Host Family Program more than 40 years ago.
The program began in the late 1970s as a way to link new international students to local families with Harvard affiliations. Run out of the College’s First-Year Experience office, the initiative has few formal requirements. Host parents often meet up with students for meals, celebrate holidays, and, most importantly, help them adjust to life at Harvard.
Gallagher, who was then married to a Harvard Medical School alumnus, became one of the first volunteers to sign on after expressing the need to support incoming students from Africa to the secretary of then-President Derek Bok. She made hosting first-years a family tradition, with daughters Maura and Claire joining the effort when Diane moved to Cape Verde to serve as a Peace Corps volunteer from 1990 to 1992.
Since then, the three women estimate they have helped dozens of students adjust to life on campus.
Diane Gallagher in her Brookline home.
Stephanie Mitchell/Harvard Staff Photographer
“It’s really been such a wonderful thread in the tapestry of the Gallaghers’ lives,” said Maura Gallagher. “It’s something that we all just enjoy immensely.”
Kevin Burke ’66 began hosting students in the 1980s. He took a break from participating in the program while raising his own family, but returned when he and his wife became empty nesters. “This time, I was able to put more time and effort into it,” he said.
Burke described his three-point process for meeting his new students. First, he picks them up at Logan Airport and drives them to campus. “It’s just really a lot of fun and a rare experience to share in the excitement, especially in cases where the students have never even been to Boston or the United States before,” he said.
Burke then takes students shopping for dorm essentials and helps them move in.
“It’s very uplifting and for me, it’s a mixture of nostalgia, optimism, and loyalty to my College,” said the Massachusetts native, who played defenseman for the men’s ice hockey team for two years.
Polina Galouchko ’23 from Moscow recalls how grateful she felt for Burke in her early days in Cambridge.
“The first couple of days, he really just took care of everything,” said Galouchko, who is now a graduate student in political science and has stayed in contact with Burke. “I was completely unaware of where one gets things, and he took me shopping and showed me around campus. It was just incredible and so helpful.”
Nekesa Straker, senior assistant dean of residential life and first-year students, said this year 142 families volunteered to host 174 undergrads, including 98 international students. An additional 65 students were put on a waiting list, highlighting the need for more hosts.
Reisa Volkert with some of her host students.
Courtesy image
Polina Galouchko and Kevin Burke.
Photo by Matthew P. Lomanno
Emmanuel Muriuki (left) and Sheila Thimba with their bracelets from Kenya.
Veasey Conway/Harvard Staff Photographer
Diane speaks about her clothing from Ghana.
Stephanie Mitchell/Harvard Staff Photographer
Maura Gallagher (right) and Ana Breznik.
Claire Gallagher.
Stephanie Mitchell/Harvard Staff Photographer
“Our expectation, really, is that they form a connection with the students. It can range from going out to dinner, having coffee, answering questions, or just being another resource,” Straker said. The First-Year Experience office also offers opportunities for hosts and students to meet up during family weekend or at various sports events on campus.
Reisa Volkert, whose husband, L. John Volkert ’56, is an alum, and Sheila Thimba, College dean of administration and finance, have grown close to all of the students they have hosted, many of whom they see regularly.
Thimba, once an international student herself at St. Elizabeth University in Morristown, N.J., from Kenya, remembered what it felt like to be in a country far from family and friends.
During the past decade, she and her husband, George, have hosted dozens of students, many from Africa, and remain in contact with many of them long after graduation. With each new student, she immediately adds them to her host family WhatsApp group.
“I think they will say that’s actually more valuable to them than talking with us old folks,” Thimba joked. “We’re useful for picking up at the airport or taking them to Target. But mostly they get to know each other. That’s been incredibly useful.”
She noted that past students who have graduated and returned to Kenya have established a “farewell committee” for first-years leaving the country to come to Cambridge.
Similarly, Volkert, who also primarily hosts students from Africa, has made it her mission to connect each new cohort of students to others who came before them and make up her extended host family.
Once at Harvard, she takes them out to dinner and shopping when they need it. “For me, this really works well in terms of being that person who would be the parent or there for what they need,” she said.
“It’s like a second family here in the United States,” said Kwame Boateng ’28, one of Volkert’s students this year. “Reisa is like a mother to us, and the other members of the host family are like brothers and sisters to me. I love them very much. We meet every two weeks for dinner, and we get to catch up away from all the academic stuff.”
“It’s like a second family here in the United States. Reisa is like a mother to us, and the other members of the host family are like brothers and sisters to me.”
Kwame Boateng
Boateng and Emmanuel Muriuki ’28, who is paired with Thimba, credited their host mothers for warning them about Boston’s tough winter weather. Muriuki, who comes from Kirinyaga County in Kenya, said he had “no idea where to start” when it came to finding warm clothing.
Thimba took him and other host students shopping for jackets and accessories that Muriuki started wearing as temperatures dipped this fall.
Two of Burke’s students, Galouchko and Sasha Khalo ’28 from Ukraine, described the enduring and endearing interactions he’s had with them — and their families.
When Khalo arrived in Boston with her mother and sister, they were all able to meet Burke. “He was just so thoughtful,” she said. “He’s a photographer, so he was taking professional pictures of us and making memories for us.”
Since then, Burke has kept Khalo’s family apprised of her time in Harvard through emails and photos.
Burke attended Galouchko’s wedding in New Hampshire the summer after she graduated, flying a camera-equipped drone over the nuptials to capture video of special moments, which he later gave to the newlyweds as a gift.
“It was super special, because we didn’t realize he was doing that. Six months later, he showed up and was like, ‘OK, here’s my gift to you guys!’” she shared. “There were so many precious moments captured from above, and it was such a unique and cool gift.”
Alumni, faculty, staff and other affiliates interested in becoming hosts can inquire with the First-Year Experience office.
Undated photo of Joseph Lindon Smith painting near the Sphinx at Giza.Courtesy of the Dublin Historical Society
Arts & Culture
An archaeological record that doubles as art
Eileen O’Grady
Harvard Staff Writer
February 3, 2025
3 min read
Painter captured ancient Egyptian tomb’s secrets in vivid brushstrokes
When artist Joseph Lindon Smith arrived in Giza a century ago, it was on the he
Painter captured ancient Egyptian tomb’s secrets in vivid brushstrokes
When artist Joseph Lindon Smith arrived in Giza a century ago, it was on the heels of an exciting discovery: a tomb chapel for a high-ranking Egyptian official named Idu dating to 2390–2361 B.C.E.
Color photography had not yet advanced enough to be of use to archaeologists in 1925, so the Harvard University-Boston Museum of Fine Arts Expedition had enlisted Smith, a former portrait artist trained in Boston, to document finds inside the Tomb of Idu. Such brightly colored renderings of archaeological sites remain valuable to scholars today.
“The monuments are changing. There’s deterioration, there’s the elements; sometimes, unfortunately, there’s mistreatment,” said Peter Der Manuelian, museum director and Barbara Bell Professor of Egyptology. “Any documentation you get from the old days that shows things in a different or better-preserved state than you see them today — maybe with more colors preserved — is always welcome.”
The painting depicts a statue of Idu from the waist up, framed within a decorative “false door” on the tomb chapel’s west wall. Ancient Egyptians would leave food offerings there, believing the souls of the deceased could freely enter and exit from the netherworld. Hieroglyphs above include spells, Idu’s name, and his job titles.
Photo of the statue of Idu emerging from the “false door.”
Courtesy of White Star Publishers
“The Royal Scribe, Idu” painted by Joseph Lindon Smith in 1925.
“There are thousands of false doors all over Egypt. What makes this one interesting is this upper torso of Idu himself, the tomb owner, as if he’s coming up out of the netherworld,” Manuelian said. “He’s even got his hands out, saying, ‘I’m ready to take the offerings.’”
In his 1925 diary, Smith wrote about painting the Idu statue, saying “I finished my study of the ‘Bachsheesh’ man and began one of his little son at the left of the doorway.” In Arabic, “baksheesh” refers to money given as a tip, likely a reference to the statue’s outstretched hands, according to Manuelian.
The underground tomb chapel of Idu was uncovered by Harvard-MFA archaeologists in 1925.
Courtesy of White Star Publishers
Scientists today chronicle dig sites using technology such as photogrammetry to make 3D models. But before photography became advanced enough to properly capture color and detail in low-light environments, archaeologists often used line drawings, Manuelian said. It’s no wonder the work of artists like Smith was highly valued by Egyptologist and Harvard Professor George A. Reisner, who directed the Harvard-MFA Expedition from 1905 to 1947 on the Giza Plateau and other sites in Egypt and Sudan.
“Reisner saw them as academically valuable as well as aesthetically beautiful,” Manuelian said. “He loved that Smith could get this three-dimensionality in his two-dimensional paintings and make them visually pleasing, but also a good source of documentation.”
Today the MFA owns more than 100 of Smith’s paintings. The Harvard Art Museums has close to 100 of his works, but only a few of these show ancient Egyptian subjects.
“We are really happy to have this connection to Joseph Lindon Smith at Harvard,” Manuelian said. “It’s an aesthetic piece, it connects to the Harvard-MFA Expedition, and it’s one of Smith’s Egyptian paintings. I think it helps tell that story.”
Campus & Community
Doing College with ball in one hand, bow in the other
Bradford Dickson.Harvard Athletics
Nicholas Economides
Harvard Correspondent
February 3, 2025
4 min read
Bradford Dickson plays on Crimson water polo team, and as a Harvard-Berklee cellist
Bradford Dickson usually dons a Speedo in preparation for matches. This time he wore a tuxedo.
Head coach Ted Minnis and
Doing College with ball in one hand, bow in the other
Bradford Dickson.
Harvard Athletics
Nicholas Economides
Harvard Correspondent
4 min read
Bradford Dickson plays on Crimson water polo team, and as a Harvard-Berklee cellist
Bradford Dickson usually dons a Speedo in preparation for matches. This time he wore a tuxedo.
Head coach Ted Minnis and a few players recruited Dickson, an accomplished cellist, to perform the national anthem before the women’s team’s senior day game against Princeton. The sophomore attacker on the men’s water polo team is one of 53 students enrolled in the Harvard-Berklee College of Music joint studies program.
“Those are some of my favorite types of performances,” Dickson said of last spring’s event. “I’m playing for all my best friends, and it brings together everything I love: the people I love, the sport I love, and the music I love — all in one. That’s really special to me.”
“It was awesome to watch Bradford bring his two passions together in the same place,” Minnis said. “He did a great job, and it showed how well-rounded he is as a student, athlete, and as a young man.”
Dickson’s musical journey began in the second grade. He initially picked up the violin as part of an elementary school requirement, but his time with that instrument proved short-lived.
“I tried the cello in third grade, and I really liked it,” Dickson said. “The cello has the closest range to the human voice. Over time, I learned that the cello could do so many things; it can be the percussion, the bass — it’s so versatile. There’s no role the cello can’t take on.”
Along with his undergraduate coursework at the College, the economics concentrator takes classes and does private sessions and public performances at Berklee, all of which will set him up to pursue a graduate degree there.
“All the classes are music-based and everything is centered around music, which I really enjoy,” Dickson said. “I get to take a wide variety of classes and receive a very open and broad music education.”
Finding a place where he could continue to study music at a high level played a significant role in Dickson’s college decision-making process. From music to academics to athletics, Harvard provided Dickson the best of all worlds, allowing him to practice cello, work toward his undergraduate degree, and play NCAA Division I water polo.
“Harvard was the only place where I could get an amazing education, play a Division I sport, and have the opportunity to pursue music at the best contemporary music school in the world,” Dickson said. “The fact that all three things aligned at Harvard was perfect.”
Whether in the pool with teammates or on stage playing the cello, Dickson credits his success to a strong work ethic and attention to detail, both of which allow him to continually improve.
“Bradford’s developed into his role as a defender on our team as he’s worked extremely hard on developing his skillset, and I’m very excited to see how he continues to progress,” Minnis said. “Out of the pool, just watching Bradford grow out of his shell and into a leader on this team has been remarkable to watch. He has been a major piece to our Boys and Girls Club program [of volunteers to Greater Boston chapters] and he’s such a great friend and role model to all his teammates.”
“Once you reach a certain level, the time you put in and the small details make a significant difference,” Dickson said. “It’s making that extra pass, practicing that shift on the cello a few more times. Those little things make us better than our competition. Cello is very similar. Everyone at Berklee can play, but when you have that extra bit of passion and the drive to be great, you stand out.”
Campus & Community
What a Hamm
Seniors Ava Pallotta (left) and Jessica Zisk kiss actor Jon Hamm during his roast Friday at Farkas Hall as Hasty Pudding’s 2025 Man of the Year.Niles Singer/Harvard Staff Photographer
Anna Lamb
Harvard Staff Writer
February 2, 2025
3 min read
Film and TV star has some fun as Hasty’s 2025 Man of the Year
Was it a slab of deli meat or the actor Jon Hamm t
Seniors Ava Pallotta (left) and Jessica Zisk kiss actor Jon Hamm during his roast Friday at Farkas Hall as Hasty Pudding’s 2025 Man of the Year.
Niles Singer/Harvard Staff Photographer
Anna Lamb
Harvard Staff Writer
3 min read
Film and TV star has some fun as Hasty’s 2025 Man of the Year
Was it a slab of deli meat or the actor Jon Hamm that Elle magazine once described as “having a characteristic Midwestern farm yumminess”? That question was one of several tricky moments in the “Ham or Hamm?” portion of Hasty Pudding’s 2025 Man of the Year ceremony Friday at Farkas Hall. You’re forgiven if you’re stumped.
Hamm, an Emmy and Golden Globe winner known for his work in “Mad Men,” “Fargo,” and the Boston-set crime drama “The Town,” was honored — and roasted — ahead of a preview of Hasty’s 176th production, “101 Damnations.” The theatrical group’s president, Catherine Stanton ’25, and cast vice president, Bernardo de Moura Sequeira ’26, poked fun at the actor’s height, handsomeness, and his relationship with fellow actor Paul Rudd. Hamm was happy to play along, reprising his “Mad Men” role, among other stunts.
Hamm with “The Real Paul Rudd” played by junior Weston Lewin.
Niles Singer/Harvard Staff Photographer
Kissing the Pudding Pot.
Niles Singer/Harvard Staff Photographer
Flanked on stage by Mattea Conforti ’28 (from left), Will Jevon ’27, and Christopher Rivers ’25.
Niles Singer/Harvard Staff Photographer
“Well, now I can say I got into Harvard,” the actor wrote as he signed the guest book.
Stephanie Mitchell/Harvard Staff Photographer
Hasty Pudding honorees through the years.
Stephanie Mitchell/Harvard Staff Photographer
Before the fun, Andrew Farkas ’82, for whom Hasty Pudding’s theater was renamed in 2018, took to the stage to welcome Hamm and to talk up the mission.
“We are an artistic and philanthropic organization whose proceeds from everything go primarily to finance contributions to performing arts-oriented educational institutions around the world,” he said. “We’ve learned that if you give people a stage and you let them write about what it is they want to write about … it does wonders for self-esteem and development, and that is what the Hasty Pudding is all about, helping everybody else while having a wonderful time together and creating art in various forms.”
After the roast, Hamm was asked about the fate of his character in the TV drama “Landman,” whom fans are concerned may not return for a second season. “I’ve said to most of the people that have seen the show, not to give spoilers or anything, but usually, when you’re surrounded by your loved ones on a hospital bed and they’re crying and the machine has a flat line on it, it’s not great.”
He also reflected on “Mad Men,” calling it “a high-water mark in my life and career.” When it comes to his humorous side, the chance to host “Saturday Night Live” was a breakthrough, Hamm said. The show’s creator, Lorne Michaels, “gave me that opportunity, which led to ‘30 Rock,’ which led to ‘Bridesmaids.’ . . . So I’ll be forever grateful to him for that.”
Asked about “The Town,” Hamm insisted that his Boston accent in the Ben Affleck-directed movie was “supposed to be bad.”
“That’s my story and I’m sticking to it,” he said before kissing his Pudding Pot.
Hasty Pudding will honor the 2025 Woman of the Year, Cynthia Erivo, with a roast on Feb. 5.
Arts & Culture
Why are so many novels set at Harvard?
Photos by Stephanie Mitchell/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
January 31, 2025
7 min read
Beth Blum notes campus is beautiful, romantic setting that lends itself to exploring collision of ideals, reality
In the 2022 novel “Tomorrow, and Tomorrow, and Tomorrow” by Gabrielle Zevin ’00, Sam Masur pitches
Photos by Stephanie Mitchell/Harvard Staff Photographer
Eileen O’Grady
Harvard Staff Writer
7 min read
Beth Blum notes campus is beautiful, romantic setting that lends itself to exploring collision of ideals, reality
In the 2022 novel “Tomorrow, and Tomorrow, and Tomorrow” by Gabrielle Zevin ’00, Sam Masur pitches a business proposal to his friend Sadie at the Harvard Museum of Natural History. “Everything I Never Told You” (2014) by Celeste Ng ’02 uses the River Houses near the John Weeks Footbridge to set a graduate-student love interest. And Selin Karadağ from “The Idiot” (2017) by Elif Batuman ’99 meets up with senior crush Ivan on the Widener Library steps.
Harvard’s campus has long served as the setting for narrative works by alumni as well as many others.
Beth Blum, Harris K. Weston Associate Professor of the Humanities, teaches an English Departmentcourse that explores books, films, television episodes, and even comics that engage with Harvard as object of cultural intrigue and critique. In her course, students discuss themes of belonging, tradition, privilege, and competition, research authors’ personal histories in the Archives, and even experiment with writing their own Harvard narratives.
In this edited conversation with the Gazette, Blum discusses the longstanding appeal of the genre, for both writers and readers.
What counts as a “Harvard Novel”? How do you define the genre?
I see the Harvard novel as a subset of campus fiction, which is simply any fiction set on a college campus — a classic example would perhaps be “Lucky Jim” by Kingsley Amis from 1954. These books are often either concerned with the tribulations of a professor who is up against a heartless administration, facing their own personal challenges and interpersonal dramas, or with the perspective of a student entering this new world and having to adjust to the realities of a very intense microcosm of the university.
Some stories are explicitly about Harvard and firmly set in the Yard, like Erich Segal’s 1970 hit “Love Story.” Zadie Smith’s “On Beauty,” which she wrote while at Radcliffe, is set at the fictional “Wellington College,” a place which shares some traits with Harvard but combines these aspects with those of an imaginary New England liberal arts college environment. Sometimes Harvard is simply part of a character’s formative backstory, as in “Everything I Never Told You” or “Tomorrow, and Tomorrow, and Tomorrow.”
What are some common themes you see across these types of novels?
One point that quickly comes across is that attending Harvard is often a family affair. It is entwined with parental expectations and sacrifices, but also with sibling dynamics. This is something we see in “Everything I Never Told You.”
Another prominent theme is student-teacher relationships and the experience of pedagogical projection or transference. In [the 1973 film] “The Paper Chase,” the protagonist, Hart, becomes increasingly obsessed with pleasing his domineering law professor, only to realize at the end that the professor barely knows who he is.
The “street-smart outsider underdog” versus “privileged Harvard insider” is another common trope. This is connected to the contrast between creative idealism and institutional assimilation.
Harvard novels can often become a sort of morality tale, where the protagonist learns to embrace their internal values over those imposed by the structures of academic competition.
Belonging is another tremendously prominent motif. The value of community, of the interesting people one meets here, becomes a focal point of the literature.
To what do you attribute the longstanding appeal of Harvard’s campus?
As my students have pointed out, the University is itself an object of beauty and history. But that romantic history can feel incongruous with the gritty realities of daily living, and the best Harvard stories bring this to the fore.
“As my students have pointed out, the University is itself an object of beauty and history. But that romantic history can feel incongruous with the gritty realities of daily living, and the best Harvard stories bring this to the fore.”
For instance, the protagonist Selin in “The Idiot” describes the University handyman having to work around the decorative antlers hanging from the ceiling of the dining hall, trying to avoid being gouged by them. The clash between apprehending Harvard spaces as romantic historical objects, as anticipated by the incoming student, and the pragmatic need to maintain such spaces, with all the labor this maintenance entails, can create poignant opportunities for contemporary fiction.
Another common tactic is to use the University’s compression of time into this four-year space to create opportunities for drama. For students, there is a limited amount of time to make the most of their courses and relations here, so the stakes feel high and lend themselves to suspense and narrative action.
Do you think these books translate the same for Harvard students versus outside readers?
In my course, we’ve found that the experience of reading many of these texts is completely different for a Harvard affiliate than for a reader unfamiliar with Harvard settings. We’ve even found that the experience of reading these works as student versus faculty is very different.
For students, one of most important and consistently compelling aspects of Harvard that comes up a lot in class discussions is the housing system, the different quirks and identities of the various Houses, the drama of House and roommate selection — a sort of updating of the medieval “wheel of fortune,” the arbitrariness of fate.
Whereas for a faculty member such as myself, the Houses are much less central to my daily experience of the University. Reading these texts affords me insights into these everyday aspects of my students’ lives.
How can it benefit current students to read these texts?
One risk of the course is that campus customs can start to feel faintly ridiculous, as if you are living in your own campus satire. But I think this is actually a healthy side effect, as it encourages a little bit of irony and detachment from institutional pressures.
But more seriously, the course makes students experience campus life, and the educational journey, in a new way. Harvard landmarks we pass every day make appearances in the writings, from W.E.B. Du Bois’s undergraduate writings on the Johnston Gate for his English 12 class, to the use of the same Johnston Gate as “the wall” for punishing rebels in Margaret Atwood’s “The Handmaid’s Tale.”
One of their assignments asks them to uncover a “Harvard story” in the University’s archive, and then attempt to reconstruct how an author’s encounter with campus culture may have informed their philosophy or artistic output. One student looked at the courses listed on E.E. Cummings’ Harvard transcript and how it may have influenced the development of his modernist aesthetic. Another examined T.S. Eliot’s critiques of Harvard’s “elective system” of education, and how they relate to his literary criticism.
On a broader level, reading these texts can help students situate themselves within a cultural tradition that they are themselves helping to shape and define, and to reflect on this institutional affiliation that will forever be a part of their lives.
If someone wants to dive into reading a “Harvard novel,” where would you recommend starting?
As a scholar of modernism, my temptation is to recommend William Faulkner’s “Absalom, Absalom!” a modernist novel published in 1936 and narrated as flashbacks by Quentin Compson to his Harvard roommate, Shreve.
But a book that I’m actually reading right now is “The Class” by Erich Segal. Like his earlier “Love Story,” it’s set at Harvard, but this novel follows five different students; it starts at their 25th class reunion and then flashes back to their freshman experiences. The double-temporality becomes both a reflection on the novelty of the student experience and a testament to how formative that experience became in the characters’ lives.
I definitely plan to incorporate it into future iterations of the course. I can’t wait to hear what the students will make of it.
Health
Different day, different diagnosis?
Study finds spike in ADHD cases on Halloween, highlighting stakes of cognitive bias in medicine
Clea Simon
Harvard Correspondent
January 31, 2025
6 min read
Anupam B. Jena (left) and Christopher Worsham. Niles Singer/Harvard Staff Photographer
In medicine, the first step is an accurate diagnosis. Yet many conditions, including attention deficit h
Study finds spike in ADHD cases on Halloween, highlighting stakes of cognitive bias in medicine
Clea Simon
Harvard Correspondent
6 min read
Anupam B. Jena (left) and Christopher Worsham.
Niles Singer/Harvard Staff Photographer
In medicine, the first step is an accurate diagnosis. Yet many conditions, including attention deficit hyperactivity disorder (ADHD), require physicians to rely on more subjective criteria such as observation of symptoms or behaviors. This opens the door for cognitive biases and external factors to influence medical assessments. In a recent paper published in the National Bureau of Economic Research, “Halloween, ADHD, and Subjectivity in Medical Diagnosis,” Harvard researchers spotted an opportunity for a natural experiment in a holiday that tends to make children hyper. Wondering whether changes in young patients’ behavior — related to the excitement of wearing a costume and collecting candy on Halloween — influence diagnosis of ADHD, they analyzed data on more than 100 million pediatric visits. They found a 14 percent increase in childhood ADHD diagnoses on Halloween compared with 10 surrounding weekdays.
We spoke with two of the study’s authors — Anupam B. Jena, the Joseph P. Newhouse Professor of Health Care Policy at Harvard Medical School, and Christopher Worsham, an assistant professor of medicine at HMS — about their findings. This conversation has been condensed and edited.
How is ADHD diagnosed?
Worsham: Speaking colloquially, ADHD is diagnosed by pediatricians and child mental health specialists over time. The goal is to assess a pattern of behavior across school life and life at home, gathering information from parents and from teachers. That said, the actual diagnosis is going to happen on a specific day. And so when the doctor is making that diagnosis, the conditions occurring on that specific day could influence whether a case that’s on the fence ends up being or not being [diagnosed as] ADHD.
Jena: There’s a formalism that goes into the diagnosis, but ultimately a diagnosis has to be made. It’s a snapshot of a given day. It’s not a laboratory test.
How does subjectivity come into play?
Worsham: The actual diagnostic criteria for ADHD have subjectivity baked in. Some of the diagnostic criteria are: “Is this kid fidgety? Is this kid moving a lot? Are they restless? Are they talking when they shouldn’t be talking?” If you are a kindergarten teacher and you’re looking at a kid’s behavior, you’re comparing it to your idea of how a kindergartner should behave. And that’s going to vary from teacher to teacher.
On Halloween, we get to focus on the subjectivity of the doctor. They’re going to have that one last piece, which is how that child is behaving in front of them on that day.
Jena: You might expect a response to Halloween in a child who either has ADHD or who is at risk of having ADHD because it’s an exciting holiday. Halloween is like a stress test.
Why does misdiagnosis matter?
Jena: Let’s say two or three children are being diagnosed. Two might be diagnosed on a non-Halloween day, and three on Halloween. That third child, that’s an extra medication prescription.
Worsham: Some of this goes to the broader discussion about ADHD. Approaching 10 percent of kids, more boys than girls are getting diagnosed. That’s a lot of kids. And the question is: Is this really a disorder? Is this some range of normal? Are medications the right answer? This is a huge debate in both medical and educational circles. There are concerns about both overdiagnosis and overtreatment of ADHD from kids who will not benefit and might be harmed by the drugs. And there are also concerns about under-diagnosis and undertreatment of kids in historically underserved populations.
Does your study shed light on ADHD itself?
Jena: What it highlights is the subjectivity of the diagnosis. Mental health diagnoses are different than physical health diagnoses. The government treats them differently. Health insurers treat them differently. The way they are diagnosed is different, in some sense necessarily. With mental health, there’s not a lab test that you can do. The question for us is how big of a deal is subjectivity and how do you measure what factors influence the subjectivity?
What controls do you think should be put in place?
Worsham: There’s a lot of literature supporting the idea of at least making people aware of the possibility of a cognitive bias. In this case, “Hey, it’s Halloween! You might be viewing this patient slightly differently than you otherwise would have. Remember that when you’re making a diagnosis.” At least planting that seed might help reduce some of the bias.
Jena: In my book “Random Acts of Medicine,” we talked about a finding a couple of years ago that showed that kids who are born in August are more likely to be diagnosed with ADHD than kids who were born in September. The reason is that kids who were born in August in states that have a Sept. 1 cutoff for entering school are the youngest kids in their class. And so their behavior is a little bit different. The implication is that those kids may not have ADHD. They’re just physiologically different because they’ve been alive for 20 percent less time than their peers who are in that same class who are nearly a year older.
If you are a physician who makes ADHD diagnoses, if you know that the child that you’re evaluating has an August birthday, you should at least pause, do a timeout, and say, “Am I making this diagnosis appropriately here?”
You can implement that kind of information very easily into an electronic health record. You have a child who’s being evaluated, and you are making a decision to write a prescription. There are multiple points at which the electronic health record could just flag you and say, “Are you aware of this possibility?”
Does this have any implications for other neurodevelopmental or psychiatric disorders?
Jena: Generally, it is interesting to think about situations where the doctor’s clinical decision could be affected by external factors that would make them more likely to make a diagnosis. For example, suppose a person is seen in a doctor’s office and the doctor is thinking about whether this person should be diagnosed with depression. Well, if a celebrity recently committed suicide or something was in the news about depression, maybe that doctor would make that diagnosis more often simply because it’s more salient in their mind.
Worsham: The other side of that coin is that this natural experiment is suited toward studying ADHD because Halloween brings out diagnostic criteria for ADHD in a way that it wouldn’t bring out diagnostic criteria for, say, an eating disorder.
The measurement is specific to ADHD, but it does tell us that maybe we should be looking for other circumstances because if we can show it here, there might be evidence of it under the right conditions for other diseases.
Research described in this story was supported by the Agency for Healthcare Research and Quality.
Robin Abrahams.Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
From sending thank-you notes to touching your co-worker’s food, she’s ruled on it all
Business School’s Robin Abrahams — aka Miss Conduct — reflects on 20 years of etiquette trends as she retires Globe advice column
Anna Lamb
Harvard Staff Writer
January 30, 2025
7 min read
Maybe you hate spending the holi
From sending thank-you notes to touching your co-worker’s food, she’s ruled on it all
Business School’s Robin Abrahams — aka Miss Conduct — reflects on 20 years of etiquette trends as she retires Globe advice column
Anna Lamb
Harvard Staff Writer
7 min read
Maybe you hate spending the holidays with your snarky brother-in-law or fear committing a social faux pas at an acquaintance’s wedding. For 20 years, Bostonians facing such quandaries have sought advice from Harvard Business School’s Robin Abrahams via the Boston Globe’s Miss Conduct column.
Abrahams, a research associate for Professor Boris Groysberg, reminisced about her career as an advice writer ahead of her final column in early February. She discussed what has changed over the years, what hasn’t, and how to be better at giving advice in everyday life. This interview has been edited for clarity and length.
Tell me a little bit more about your work at Harvard and how, if at all, it has related to writing an advice column.
I’ve had the column for about six months longer than I’ve been working at Harvard Business School. Professor Groysberg specializes in organizational behavior, and so a lot of what we’ve studied, and stuff that I’ve read up on and written on, is very applicable to what’s going on, because it’s group dynamics.
One of my favorite questions was from a young teenager who was babysitting and didn’t get the rate that she had expected. I had this whole thing about, “You’re a teen, so it’s fine if you don’t handle it perfectly, but afterwards, think about what worked well and what didn’t, and write down some notes about how you felt about the whole experience. Because someday you’re going to maybe start your own business, or get that big account, and you’re going to have a difficult client, and you’ll want to know that you dealt with this before.” I didn’t used to think that way, I wasn’t a business-minded person, so there’s been a tremendous level of synergy, and I’ve really enjoyed that.
What other kinds of questions have you answered as Miss Conduct?
Certain questions have come up over and over and over again, and the No. 1 is still thank-you notes. So many questions about friends, Romans, countrymen, grandchildren, and whoever not sending thank-you notes. I probably get about as many from people saying, “I keep putting no gifts on invitations, and yet people will bring me gifts, and I don’t have room.” After a while, you’re not going to do those anymore.
It’s also been kind of a big 20 years, and a lot’s gone down. So I’ve gotten a fair bit of social-change questions.
One of my favorite questions was when gay marriage was legalized in Massachusetts and a guy wrote in saying his brother and his brother’s partner were getting married, and he was the best man. He said, “I know best men throw the bachelor party, but they’re two guys, and they had the same friend group in common, and they’ve been together for 20 years, and what do we do?” I’m like, “I don’t know! Talk to your brother about it.” Even for straight couples, there’s a lot of variety. It’s not always the Vegas and hookers and blow kind of thing. Our ideas about marriage are different.
COVID, of course, was huge. And I wondered for a while, how I could be this alleged expert on social and organizational behavior who never leaves her house? But it turned out that there was some good stuff coming out of that. How do we not make each other sick came up a lot during COVID. “My co-workers touch my food.” “I see people who don’t wash their hands.” “There are people coughing on the subway.” That’s just a thing about living in groups. We have people with invisible disabilities. A woman wrote to me once saying she had a neurological condition that frequently made her appear drunk in public. We don’t live in a village anymore where everybody knows each other.
And the financial crisis in ’08 was really heartbreaking because I had a lot of people writing about not being able to do what they used to do socially. “I used to host a Christmas party, and I can’t this year.” Or “I know my kids can’t afford to give their teachers gifts.” And just people feeling so much shame and inadequacy, and I was like, “It’s not your fault.”
“I get an awful lot of questions that are fundamentally serenity prayer answers. You know, you can only control your own behavior.”
One thing that this column has really taught me is to be comfortable with being helpless. Being comfortable with saying, “That’s a really bad problem, and I don’t know the answer. There might not be an answer, but I see you, and I can help you understand why this is happening and that it’s not your fault and it’s not like you’re not smart enough to have figured out what to do.”
Do you think that there is a way to categorize the kinds of responses that people are looking for when they come to you for advice? Do certain people want to be coddled, want tough love, or just want to vent?
I don’t think I’ve gotten quite as many of the “I’m so clearly wrong, but I am so convinced I’m right.” Honestly, I always kind of envy other columnists who get a little bit more of those, because they can be fun. I have gotten a few, and especially since I have a really short word count, I give them advice as if their hearts were pure and make it very clear that this is what a good person would do.
I get an awful lot of questions that are fundamentally serenity prayer answers. You know, you can only control your own behavior. One thing I’ve repeated so many times over the years is the people who taught you manners when you were a little kid lied. There are no magic words. There is no way to tell someone they’re not getting something they want without making them unhappy. It doesn’t matter what they want.
Has anything drastically changed over the years that’s reflected in people’s questions?
The normalization of hate and the fact that people have to deal with that. When I started writing the column I said I don’t get directly political questions, and I do now. People are really afraid of being victims of bigotry — and that’s been an absolutely huge change, more ongoing than COVID.
Have you ever wished you gave different advice to someone?
At 30,000 feet, yes, but I don’t know what those questions are, because I used to do live chats, which was a really a lot of fun. But I wound up taking my advice back about half the time because people wouldn’t tell you everything. Someone would be like, “Whenever my friend and I go out for coffee, I always wind up picking up the tab.” You should say that, by the way, she’s my kidney donor. Maybe buy her a coffee.
Do you have advice for either seeking out or giving advice in our everyday lives?
Asking for feedback is absolutely fantastic. Do it more than you think you need to, because not only does it give you information, it builds relationships. People like being asked advice. It makes them feel powerful and connected, and that’s what people want to feel.
And be clear when you are asking for advice and when you are not, and what kind of advice you’re asking for. That was something that I learned from my mother, because if she was going to complain about something, she would always say “I’m just saying this to vent,” or “I need help figuring this out,” or “I just want you to hate this person with me for a while.”
Nation & World
Who’s softer on crime? Democrats or Republicans?
Justin de Benedictis-Kessner.Veasey Conway/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
January 30, 2025
7 min read
Turns out neither. New research finds mayors on both sides mixed in implementing effective policies.
Many Republican political candidates and leaders accused their Democratic counterp
Turns out neither. New research finds mayors on both sides mixed in implementing effective policies.
Many Republican political candidates and leaders accused their Democratic counterparts of being soft on crime during the run-up to the 2024 elections. Concerns over the safety of the nation’s cities has been a longstanding — and potent — political issue.
But how much influence do elected officials actually have over crime rates? Are localities with Democratic mayors less safe than those run by Republicans? Are they less generous with funding for police or more prescriptive on enforcement or diversity in hiring? New research examined data from 400 U.S. cities over nearly three decades and found the political affiliation of mayors made little difference when it comes to crime rates and policing.
The Gazette spoke with one of the researchers, Justin de Benedictis-Kessner, associate professor of public policy at Harvard Kennedy School, about what they learned. Interview has been edited for clarity and length.
What compelled your team to look into whether there was any data to back up partisan claims of whether one side was better on crime?
I don’t think those are just made-up claims coming from one side of the partisan aisle. One of the really interesting things about crime, specifically in cities, is that people on both sides of the partisan aisle have made claims that Democratic cities are not well-run, especially on crime and public safety. That includes everyone from President Trump, making claims that Democrats have driven cities into the ground and made them more dangerous, to post-2024 election, people on the Democratic side of the aisle saying that Democratic city leaders are not approaching crime well, and they’re not satisfying voters.
So, we wanted to get at the claim: Relative to Republican city leaders, are Democratic politicians making cities more dangerous for people in any way? Are they changing the way police are funded or staffed over the last three decades? And if they are funding the police at lower levels, is that leading to higher levels of crime?
Your research looked at the effect mayors had on police spending and staffing, and how their political leaning influenced the racial and gender composition of police forces and police chiefs. What did you find?
A lot of the post-2020 rhetoric around policing is about how Democrats are rethinking the role and enormous budgets of police departments in cities across the country. A lot of Democrats claim they’re changing the way policing happens — diversifying the police force, reducing racial disparities in arrests, changing the way it’s funded. We wanted to address that claim as well. Are Democratic and Republican mayors decreasing funding of the police, the way they’re staffed, and the way they make arrests, especially with relation to race? And it turns out, that claim is not true either.
Democratic politicians aren’t cutting the budgets of police, and they aren’t making the police force vastly less white relative to Republicans. They’re not increasing the number of women police officers. These are characteristics that might make a huge difference in how the police are perceived by the community and how they go about their jobs. If we saw changes in the people hired to be police officers, other research suggests we’re going to change racial disparities in people’s interactions with the police and police officers’ use of force against civilians. But we just don’t see those demographic effects.
And we don’t see those downstream differences in terms of how racialized the contact between people in cities and the police is. Some of our results are suggestive that Democrats might reduce the Black share of arrests, but these results are definitely not conclusive.
If there was a true effect, say, on the racial composition of arrests, we would expect all of our analyses to come back with the same answer, or at least in the ballpark of the same answer. We instead find what looks like maybe a negative effect on the Black share of drug crime arrests, and maybe the Black share of total arrests, but they’re not a large enough effect and not consistent across the many research designs we use.
So, we can’t say with a large degree of confidence that these aren’t the same results we would see if there were just chance differences across cities. And so I wouldn’t interpret these results to say, “Democrats are reducing racial disparities in arrests.” If Democratic leaders are doing that, they’re not doing it to a degree that is statistically detectable from how Republicans are changing the racial composition of arrests.
Politicians often point to a city’s overall crime rate or a reduction in certain types of crimes as evidence of their success. What influence do a mayor’s politics have on crime rates or the types of crimes committed?
I think anyone in the field of criminology would know that it’s not just local policies, at least in the short term, that are going to lead to big crime or arrest differences. Arrests are a discretionary policy choice by a police force, but crime is the result of a lot of different things. It’s not just the result of how many police you have and how well they’re doing their job. It’s the result of everything from economic conditions to youth job training programs to diversionary post-prosecution programs that reduce recidivism — all of these play a role. The national economic outlook could play a large role in reducing crime relative to a specific policy made by a mayor.
Often, these policies are having some marginal impact, but they’re rarely going to make huge shifts in crime, and they’re definitely not going to do it immediately.
Crime is a really hard problem to solve. You can’t just make one policy and crime disappears. So, blaming one party or the other for increases in crime is counterproductive to the goal of increasing public safety in cities.
Over the last 30 years, nearly every city in the United States has seen a big decrease in crime, both violent crime and property crime. But within cities, it fluctuates quite a great deal. Individual cities are going to see some fluctuations in crime and arrest rates.
It’s easy to try to point the finger at a specific mayor or other local politicians like prosecutors, but often it has to do with a systematic trend. Maybe they can make changes at the margin, which many of them do, but it’s often going to be hard to attribute those changes to a specific policy made by a specific politician.
So, neither party deserves credit when crime is down and shouldn’t be blamed when crime is up?
Exactly. There are a lot of policies that might make a difference in crime, but neither party is doing a better job than the other party at implementing those.
What were some things you weren’t able to measure or detect in this study that merit further investigation?
I think a lot of future research, and something that I know a lot of other researchers are working on right now, is looking at a single city or a handful of cities in the last five years and gathering really in-depth data on policy changes, police behavior, and crime or interactions between citizens and the police.
A lot of those researchers are doing a great job at informing policy in terms of how we can change how the police are perceived by the community, how we can improve citizen interactions with the police, and how we can decrease crime in a way that’s going to help public safety for everyone and reduce racial biases.
Our study shows that these things have very little, it turns out, to do with partisanship and who the political leaders are in a partisan sense. They likely have much more to do with our police forces being trained differently or hiring different people. That’s where a lot of the really promising research is. I’d love to see claims from politicians about some of that evidence on what actually works, and pointing to their efforts to implement those policies in cities.
Nicholas Carr.
Nation & World
Who can save us from social media? At this point, perhaps just us.
Nicholas Carr argues it may be too late for regulation as platforms took hold so quickly, outpacing our ability to spot darker effects on society, democracy
January 29, 2025
long read
Excerpted from “Superbloom: How Technologies of Connection Tear Us Apart” by Nicholas Carr, M.A. ’84.
It was a Sunday
Who can save us from social media? At this point, perhaps just us.
Nicholas Carr argues it may be too late for regulation as platforms took hold so quickly, outpacing our ability to spot darker effects on society, democracy
long read
Excerpted from “Superbloom: How Technologies of Connection Tear Us Apart” by Nicholas Carr, M.A. ’84.
It was a Sunday night, Oct. 19, 1952, and Frank Walsh, a Long Island electrician who moonlighted as a security guard, was worn out. He headed upstairs to bed while his wife, mother-in-law and five kids stayed down in the living room watching TV. They were engrossed in the latest episode of the new hit comedy “The Abbott and Costello Show.” Walsh tossed and turned but couldn’t fall asleep. The television was too loud, the laughter jarring. His irritation mounted, then turned to rage. He got up and grabbed the .38 Special he used in his guard job. Halfway down the stairs, the offending set came into view. He paused, took aim, and fired a bullet through the screen.
Walsh’s wife, furious, called the police. Officers arrived and confiscated the revolver, but they made no arrest. There’s no law, they explained, against shooting one’s own television. Two days later, The New York Times ran a brief, tongue-in-cheek notice about the incident, under the headline “Obviously Self-Defense.” The day after that, a Times columnist, Jack Gould, praised Walsh’s “public-spirited act.” He called on the authorities to give the man his gun back. “His work has barely started.” The paper’s coverage turned Walsh into a celebrity. Within a week, he appeared as a contestant on the popular prime-time game show “Strike It Rich.” He won a TV.
To shoot a television set, Frank Walsh discovered, is not to strike a blow against media and its dominion. It’s to merge into the televisual. It’s to act as someone on TV would act. As the producers of “Strike It Rich,” not to mention the editors of The New York Times, immediately recognized, Walsh’s shooting of his television was a made-for-media event — outrageous, funny, violent, relatable. Flattened into a figure of amusement and funneled into the media flow, Walsh succeeded only in turning himself into content. His act lived on, though. Firing a gun at a television would become a cultural trope, replayed endlessly in books, movies, songs, cartoons, and, of course, television shows. Elvis Presley made a habit of shooting his TVs and burying the carcasses in a “television graveyard” behind Graceland. He would then go out and buy more sets. He kept upwards of a dozen televisions in various locations around his mansion, plugged in and broadcasting. In surrounding himself with screens, the King was a trailblazer. We all live in Graceland now.
***
Thanks to its lack of attachments, its promiscuous flexibility, mass media has always been resilient. It absorbs the criticisms directed at it (even when they take the form of projectiles), turns them into programming, airs them, then distracts us from them with the next spectacle. Social media goes a step further. By encouraging an overheated style of rhetoric that breeds political polarization and governmental paralysis, it reduces the chances that it will be subjected to meaningful regulations or other legal controls. It’s protected by the conditions of distraction and dysfunction that it fosters. Politicians go on social media to express their disdain for social media, then eye the like count.
That’s not to say reform is impossible. The European Union, which has been much less sanguine than the United States about jettisoning the secrecy-of-correspondence doctrine, regularly passes laws and regulations aimed at restraining social media platforms. The rules provide citizens with more control over the information they share and the information they receive. Europeans are able to opt out of data-collection regimes, targeted advertising programs, and even, as of the summer of 2023, personalized news feeds. But the controls, however salutary, haven’t really changed the way social media operates. The reason is simple: they haven’t changed the behavior of most users. As surveys show, consumers have grown accustomed to trading personal information for tailored products and services. Few of them at this point are going to opt out of receiving content geared to their desires. Personalization has become central to people’s experience of media and to the enjoyment they derive from it. For avid TikTokers, taking the For You out of the For You page would be tantamount to switching off a pleasure center in the brain. Strong engagement isn’t only good for the platforms; users like it, too.
Antitrust actions against companies such as Google and Meta, which may be justified in economic terms, are also unlikely to change social media’s workings. Technological progress has an inertial force that rolls on independently of the maneuverings of the companies making money off it. While breaking up the tech giants or curbing their ability to enter into oligarchic alliances might well intensify competition and innovation in the internet industry, it’s unlikely to push media off the technological path it’s already on — a path that has been and will continue to be appealing to consumers and lucrative for companies. The point of antitrust prosecutions, argues Tim Wu, the Columbia law professor, is not to punish the big platforms but to force them “to make way for the next generation of technologists and their dreams.” That sounds stirring — until we remember that it’s the dreams of technologists that got us into our current fix. The next wave of innovations — larger language models, more convincing chatbots, more efficient content generation and censorship systems, more precise eye trackers and body sensors, more immersive virtual worlds, faster everything — will only drive us further into the emptiness of hyperreality.
The boldest and most creative of social media’s would-be reformers, a small group of legal scholars and other academics, joined by a handful of rebel programmers, have a more radical plan. They call it frictional design. They believe the existing technological system needs to be dismantled and rebuilt in a more humanistic form. Pursuing an approach reminiscent of the machine-breaking strategy of the 19th-century British Luddites, if without the violence, they seek, in effect, to sabotage existing social media platforms by reintroducing friction into their operations — throwing virtual sand into the virtual works.
“The relentless push to eliminate friction in the digital networked environment for the sake of efficiency,” explain two of the movement’s leading thinkers, Villanova’s Brett Frischmann and Harvard’s Susan Benesch, in a 2023 article in the Yale Journal of Law & Technology, has imposed large, hidden costs on society. “A general course correction is needed.” Invoking the “time, place, and manner” restrictions that have long been imposed on public speech — the prohibition on using a megaphone on a neighborhood street in the middle of the night, say, or the requirement that protesters get a permit before marching through a city — Frischmann and Benesch argue that legal restrictions can in a similar way be imposed on media software to encourage civil behavior and protect the general public interest. Unlike antitrust actions, privacy regulations, and opt-in requirements, which fail to address “the rampant techno-social engineering of humans by digital networked technologies,” government-mandated design constraints would, they write, transform the “digital architectures [and] interfaces that shape human interactions and behavior.” The constraints would change social relations by, to once again draw on sociologist Charles Horton Cooley’s terms, altering the mechanisms that determine how information flows and associations form.
Many kinds of “desirable inefficiencies” have been proposed. Limits could be set on the number of times a message can be forwarded or the number of people it can be forwarded to. The limits might become more stringent the more a message is shared. A delay of a few minutes could be introduced before a post appears on a platform, giving the person doing the posting time to reconsider its content and tone and slowing down the pace of exchanges. A similar delay or a few added clicks could be imposed before a person is allowed to like or reply to someone else’s post. A small fee might be required to broadcast a post or message to, say, more than 1,000 recipients. The fee might be increased for 10,000 recipients and again for 100,000. A broadcasting license might be required for any account with more than a quarter million followers or subscribers. Pop-up alerts could remind users of the number of people who might see a post or a message. Infinite scrolls, autoplay functions, and personalized feeds and advertisements could be banned outright.
There’s much to be said for the frictional design approach. It introduces values other than efficiency into media technology, and it would promote the construction of networks that, like the analog systems of old, encourage more deliberation and discretion on the part of viewers and listeners. If “code is law,” as Harvard Law School professor Lawrence Lessig argued years ago, then shouldn’t the public’s values and interests be taken into account in the formulation of software that shapes how society works? We have speed bumps on roads to slow people down and safeguard the public; why not on the net? The approach also has precedents in recent experiments undertaken by the platforms themselves. In 2020, some Twitter users began seeing a pop-up asking “Want to read the article first?” when they were about to retweet an article they hadn’t read. The pop-ups stirred some irritation — “Who made you god?” one user tweeted — but they did seem to have an effect, increasing the likelihood that people would at least glance at an article before sharing it. Two years later, Twitter tested a similar pop-up to deter “abusive language” in tweets. It, too, seemed to have an effect, with users canceling or revising about a third of the flagged messages. Apple and Instagram have introduced algorithmic interventions aimed at curbing the exchange of nude photos among minors. Teenaged users of Apple’s Messages and Instagram’s direct-messaging service are warned before sending or receiving messages that include nude images, and the images themselves are sometimes automatically blurred.
But while frictional design may help curb certain well-defined types of undesirable online behavior, it is likely to prove as futile as Frank Walsh’s gunplay when it comes to changing how social media operates. Unlike traditional time, place, and motion laws, which don’t affect the day-to-day lives of most people, changes to the basic workings of social media would affect pretty much everyone all at once. Although the frictional design proposals focus on regulating how technological systems work rather than on what people say, they would still raise free-speech and free-press concerns. Many people, even among the growing number who would like to see stiffer controls placed on platform companies, would rebel against what they’d see as patriarchal overreach or nanny-state meddling. Others would object to the government imposing a single set of values on the general public’s means of communication and entertainment. Many would ask whether politicians and bureaucrats can be trusted to meddle with software without mucking everything up. Would every shift in the political winds bring sudden and confusing alterations to the way apps work?
The biggest obstacle to adding friction to communication, though, is likely to be the habits of social media users themselves. The history of technological progress shows that once people adapt to greater efficiency in any practice or process, reductions in efficiency, whatever the rationale, feel intolerable. The public is rarely willing to suffer delays and nuisances once it has been relieved of them. In a culture programmed for ease, speed, and diversion, friction is the hardest of all sells.
The distinguished technology historian Thomas Hughes, having spent decades studying electric utilities, manufacturing plants, and transportation and communication networks, argued that complex technological systems are difficult if not impossible to change once they become established. In a system’s early, formative days, the public has an opportunity to influence how it’s designed, run, and regulated. But as it becomes entwined in society’s workings and people’s lives — as the technology gains “momentum,” in Hughes’s formulation — it resists alteration. Changing the system in any far-reaching way causes too many disruptions for too many people. Society shapes itself to the system rather than the other way around.
In the 1990s, when the internet was just beginning its transition from an academic to a commercial network, we could have passed laws and imposed regulations that would have shaped the course of its development and, years later, influenced how social media works.
We could have updated the secrecy-of-correspondence doctrine for a new era of online communication. We could have applied the public-interest standard to internet companies. We could have made the companies legally responsible for the information they transmit. We could have drawn technological and regulatory distinctions between private and public communication. But none of that happened. It was hardly even talked about. The public’s enthusiasm for the web and its apparent democratizing power, an enthusiasm that swept through Congress, the White House, and the Supreme Court, was too strong. Our faith in the benefits of ever more efficient communication overrode any concerns about risks or unintended consequences. Now, it’s too late to rethink the system. It has burrowed its way too deeply into society and the social mind.
But maybe it’s not too late to change ourselves.
Copyright (c) 2025 by Nicholas Carr. Used with permission of the publisher, W. W. Norton & Company, Inc. All rights reserved.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Arts & Culture
More than kind of blue
Imani Perry’s lyrical new book weaves memoir, history to consider central place of a color in Black America
Nikki Rojas
Harvard Staff Writer
January 29, 2025
7 min read
Imani Perry often slept in her grandmother’s bedroom as a child. The walls were grayish, a tile missing in the ceiling,
Imani Perry’s lyrical new book weaves memoir, history to consider central place of a color in Black America
Nikki Rojas
Harvard Staff Writer
7 min read
Imani Perry often slept in her grandmother’s bedroom as a child. The walls were grayish, a tile missing in the ceiling, which had been dropped to save on heat. Through that gap, she could see the room’s original color, a bright blue “like the sky in August.”
In her latest book, “Black in Blues,” the National Book Award-winning author reimagines the gap as a “portal” to consider the significance of the vibrant color within Black history and culture. Perry weaves memoir and history to consider shades of blue from Africa, across the Atlantic, and to the Americas through the eyes of the Black diaspora.
The Gazette spoke with Perry, the Henry A. Morss Jr. and Elisabeth W. Morss Professor of Studies of Women, Gender, and Sexuality and of African and African American Studies, and Carol K. Pforzheimer Professor at the Harvard Radcliffe Institute, about her new book, the first since her 2022 bestseller “South to America.” This interview has been edited for clarity and length.
What was the writing process like for “Black in Blues”?
I was really inspired by African American artist Romare Bearden. There’s this article where music critic and novelist Albert Murray describes Romare Bearden’s process of making collages. You look at the painting, and you see an image of something, but each of the pieces he’s cut out are in and of themselves art pieces.
Trying to put them all together to make a picture in a way that coheres or that makes sense was, for Bearden, the way that the aesthetics of [classical jazz] made their way into his visual work. For me, that’s how both make their way into my written work. Trying to get that compositional piece that I am so inspired by both visual arts and music.
The book reads as both a memoir and a lesson in Black history and culture. Why was it so important for you to weave in your personal experiences and connections to the color blue into this project?
Much of what I was sensing my way toward — and I mean sensing on not just an emotional level, but an emotional, intellectual, and spiritual level — was rooted in experiences and encounters with blue. So, that piece was important.
The relationship I felt to blue that came about as a result of sleeping in my grandmother’s bedroom was important. In some ways, I treat this missing tile and her ceiling as the portal that becomes this pathway for me to think about — not just why it produced this feeling and why I was seeing all these things, but then figuring out how to tell a story about that.
Your book underscores the fact that blue is often written about and explored by Black writers, scholars, and artists. Why do you think that is?
On one level, it’s because of the universality of blue. That is to say, blue is cherished the world over, and you can find references to blue in every tradition.
There’s something, in particular, that takes shape in Black life that is a result of the reality of the transatlantic slave trade and our relationship to ports. These were places that were nurturing and of worship and reflection that become places of devastation. That is part of why I say that Black life is a water epic. That crossroad of the site of the disaster, but also these places where people continuously go to have kind of spiritual encounters.
I try to make clear at the beginning of the book this idea of Black people as relatively new in human history. People were all these other things. It is a concept that comes about through empire and the disasters of empire, but people make something meaningful of it.
That also has to do with the color blue. I think that’s why the music became known as blues music. Blue is contrapuntal. It’s both a color of sorrow and joy. It’s the color of the water as terror, but also as possibility.
“Blue is contrapuntal. It’s both a color of sorrow and joy. It’s the color of the water as terror, but also as possibility.”
Early on in “Black in Blues” you write: “Black was a hard-earned love. But through it all, the blue blues — the certainly of the brilliant sky, deep water, and melancholy — have never left us … the blue in Black is nothing less than truth before trope. Everybody loves blue. It is human as can be. But everybody doesn’t love Black — many have hated it — and that is inhumane.” Can you delve into that powerful passage?
At the core I want to make clear that there’s this color that captivates people because it’s a universal human experience. We see the waters, and we see the sky. And it does this work upon us.
Then you have this categorization of human beings that’s meant as degradation and insult. But because we are human, we make something meaningful — even out of that condition — and create culture and art. All of these things are at once an insistence upon the fullness of the humanity of Black people and also an engagement with this universally captivating color.
You later discuss the revival of the blues and the renaissance of writing by Black women in the 1970s and 1980s. Why do you feel like this was such a distinct period for the color, sound, and artistry of blue?
In a sense, the mainstream Civil Rights Movement is an olive branch. It’s an insistence upon rights, but it’s also an olive branch to the larger society, from Black Americans, that is met with some legal gains, but also in many instances, with hostility, whether it’s white flight or the backlash against civil rights. Then there’s a moment of turning inward in Black communities. There’s this extraordinary bubbling up of artistic production.
For Black women, this also becomes particularly important, because we had the women’s movement, the beginnings of the gay rights movement, as well as Black Power. All these movements are people who have been on the margins, finding voice and space.
In this combination of the power of the freedom, you get this beautiful outpouring of creative production and access to mainstream publishing houses for the first time. For me, that work was being made literally as I was coming of age. I was born in 1972 and all of that work of the ’70s was all around me. It was an inheritance that I feel very passionate about.
What are you hoping readers take away from this latest project?
I always think of my books as artifacts, and I hope people find them interesting and pleasurable, or at least moving. But more than anything, I think of them as offerings that are companion pieces to living and to other work. I hope my readers will read a passage and then they’ll go out in the world, and something will resonate in the way that they encounter blue, and it will spur ideas, or become somehow nurturing, healing, or inspiring.
With all of my books — and my work in the classroom — I’m always both standing in a tradition and in a conversation. I’m always sort of trying to emphasize these threads of connection with other people, present and past and future. I want to make an invitation to the people who read the book to be in conversation with me.
Sina Schuldt/AP photo
Health
Gambling problems are mushrooming. Panel says we need to act now.
With recent leap in legalized sports betting and online options, public health experts outline therapeutic, legislative strategies
Clea Simon
Harvard Correspondent
January 28, 2025
5 min read
Problems with gambling issues have surged over the past half-dozen years with the rise of legalized sp
Gambling problems are mushrooming. Panel says we need to act now.
With recent leap in legalized sports betting and online options, public health experts outline therapeutic, legislative strategies
Clea Simon
Harvard Correspondent
5 min read
Problems with gambling issues have surged over the past half-dozen years with the rise of legalized sports betting and 24-hour online casino games. It’s gotten to the point where some researchers say something needs to be done now — and there are remedies.
That was the conclusion of a panel of public health and gambling experts gathered at a Zoom panel moderated by WBZ-TV journalist Laura Haefeli and hosted by the Studio at the Harvard T.H. Chan School of Public Health.
Betting on the election, stocks, and more has become common, said Timothy Fong, co-director of UCLA Problem Gambling Studies Program. Although gambling has been “part of human behavior for hundreds of thousands of years,” said Fong, this new surge “is not only endemic … it has changed the fabric of our bodies and our minds.”
A confluence of the gambling, technology, and financial industries has made this possible, added Shekhar Saxena, a Chan School adjunct professor of global mental health. “Tech makes sure the experience is seamless; the gambling industry make it tantalizing; and the financial industry makes it possible to put your money in with just a click or a tap,” he said. The combination “makes it more dangerous.”
Currently sports betting in casinos or racetracks is legal in 38 states and Washington, D.C., and at least 27 of those allow wagers online. Experts date the proliferation to a 2018 Supreme Court decision that struck down a federal law banning legalized sports betting in most states.
In addition, seven states allow online casino games and one other, Nevada, permits poker.
2.5 millionAmericans have severe gambling problems, according to the National Council on Problem Gambling
The National Council on Problem Gambling estimates that about 2.5 million adults in the U.S. have severe problems and another 5 to 8 million have significant issues. And the dilemma may be getting worse, as gambling addiction hotlines have noted a rise in calls, and the age of callers is skewing younger.
Industries, particularly sports betting, are targeting young people, said Lia Nower, director of the Center for Gambling Studies and co-director of the Addiction Counselor Training Certificate Program at the Rutgers University School of Social Work.
“The groups most at risk are emerging adults and adolescents,” she said. Citing an upcoming study, the school’s associate dean for research noted how various workarounds, such as framing gambling as “sweepstakes,” help the industry evade age restrictions to lure new and younger gamblers.
Other well-known risk factors include low education and low economic status, said Victor Ortiz, director of the Massachusetts Office of Problem Gambling Services. That, however, is changing. Increasingly, he explained, “What we are seeing is that people with higher economic status and higher education are now at risk. We’re getting calls from people in significant distress who are not our typical callers.”
The problem, said the experts, is exacerbated by the constant availability of online gaming. Nower summoned an image of people “lying in bed [gambling] while their partners are asleep.”
“Online gambling is a public health issue and requires a public health strategy,” Ortiz said.
For starters, Fong said, recasting problems as a “gambling disorder” is a necessary step toward addressing it. Making clear that it is a mental health disorder with biological, psychological, and social components, he continued, helps alleviate the shame often attached to those unable to control their gambling.
This also helps the public understand that, as with other such disorders, medication and psychotherapy can help and can reconnect the sufferer with their family and community. “When you come into treatment,” he said, “you are going to do a lot better.”
“We need a federal presence like we have for cigarettes, alcohol, and other forms of addiction.”
Lia Nower, Center for Gambling Studies, Rutgers University School of Social Work
Enacting legislation to address the problem is the next step, experts agree.
“We need a federal presence like we have for cigarettes, alcohol, and other forms of addiction,” said Nower. Specifically, she noted the need for legislation that mandates online apps have an “opt out” system for various controls.
Right now users must specifically request to opt in to access controls that will automatically limit factors such as how much time they spend in the app and how much money they can spend. That setting should be the default, she said.
The recent surge in online gambling has left researchers, public health officials, and legislators playing catch-up.
“We don’t have advocacy groups and, unlike with substances, no one is tracking gambling-related health problems, gambling-related suicides, so we don’t have the public health data like we had with alcohol, like we had with cigarettes,” noted Nower. “And there’s a lot of shame, so families aren’t coming forward.”
“Responsible gambling is something that companies love to talk about,” added Saxena. “That puts the responsibility on the individual.”
This is especially problematic because of the shame surrounding gambling disorder, he explained. Framing the issue as one of public health instead of one of self-control involves “talking about the environment, the kind of incentives that are there.”
“Yes, people have some responsibility, but it’s the environment — the tech environment, the social environment, and the economic environment in which people live — that is important,” he stressed.
Credit: CDC
Health
One way to save lives in jails
Researchers who studied healthcare in dozens of facilities link accreditation to better collaboration and treatment and fewer deaths
Christina Pazzanese
Harvard Staff Writer
January 28, 2025
6 min read
A 1976 Supreme Court decision said that while the Constitution requires that incarcerated people receive healthcare, the quality of the car
Researchers who studied healthcare in dozens of facilities link accreditation to better collaboration and treatment and fewer deaths
Christina Pazzanese
Harvard Staff Writer
6 min read
A 1976 Supreme Court decision said that while the Constitution requires that incarcerated people receive healthcare, the quality of the care doesn’t need to be top-notch, only “reasonably adequate.”
Too often, it’s not adequate, according to Marcella Alsan and Crystal Yang, who study healthcare in U.S. correctional facilities.
In a first-of-its-kind study, the researchers found that jails that undergo accreditation, like most hospitals, saw a marked improvement in healthcare delivery and standards, a substantial decrease in deaths, and millions in cost savings.
To identify accreditation’s potential effects, the researchers conducted a randomized trial of 44 jails over a four-year period. Half (described as treatment facilities) were given generous subsidies toward accreditation costs, while the other half (control facilities) were offered a more modest subsidy at the end of the study. Jails hold people awaiting adjudication on a short-term basis and are usually run by local law enforcement. The population experiences higher-than-normal rates of hepatitis and sexually transmitted infections and faces a range of mental health challenges.
In this edited conversation with the Gazette, Alsan, Angelopoulos Professor of Public Policy at Harvard Kennedy School, and Yang, Bennett Boskey Professor of Law at Harvard Law School, discuss their findings.
What prompted this study and how would you characterize the quality of healthcare provided to people in jail?
ALSAN: We had been looking at the intersection of health and corrections and we realized that there were some key differences between the healthcare you and I might receive as civilians and the healthcare people who are incarcerated receive. People who are incarcerated have a constitutional right to healthcare; they’re the only group that does. Over 90 percent of hospitals are accredited, but there’s nothing like that for corrections.
YANG: The quality of healthcare is generally quite low and varies to a great degree. Our study focused on county jails; you might see more uniformity and a little more oversight at state prisons or federal prisons. In July, President Biden signed a Federal Prison Oversight Act that sets up an inspector general to perform independent audits of all federal Bureau of Prisons facilities. That type of framework doesn’t exist for our nation’s 3,000-plus county jails. It’s estimated that only about 17 percent of all correctional facilities have voluntarily sought accreditation.
There are unique problems specific to the correctional setting. One is that there are major staffing retention and recruitment concerns. That means there might be difficulties with getting high-quality personnel and with training. That’s where accreditation might help, because there are standards that govern personnel and training.
Crystal Yang.
Courtesy photo
What are some of the study’s most significant findings?
YANG: Collaboration between custody staff and medical staff is crucial to the delivery of healthcare in correctional facilities. We administered confidential staff surveys at the beginning of the study, as well as the end. One of the things that significantly improves is collaboration and coordination between medical and custody staff. That suggests accreditation is helping people work together better.
There were two major categories of quality standards where we saw increased compliance at treatment facilities versus control facilities. One is personnel and training. We also see substantial improvements in patient care and treatment — improvements in timeliness of early stage screenings for everyone who’s admitted. If county jails are analogous to an ER, it’s really important to get individuals in front of a qualified healthcare professional immediately after admission to figure out the best course of treatment.
Maybe the biggest finding is a 90 percent reduction in mortality in the treatment versus control facilities. That comes out to an estimate of almost 20 lives saved during the study. That’s huge, and makes accreditation also highly cost-effective. We also find suggestive reductions in six-month recidivism among individuals booked into the treatment facilities. This points to potential improvements in community safety. If you do a rough cost-benefit analysis, the net benefit of accreditation can be upward of $60 million in terms of saved lives and suggestive reductions in recidivism per jail per year.
Marcella Alsan.
Niles Singer/Harvard Staff Photographer
Why does accreditation appear to have a positive effect?
ALSAN: What we learned from this experience is that there are very few instances where people are intending to produce harm. Oftentimes people don’t have the information they need as to how they should be conducting their training procedures, delivering their healthcare services. Sheriffs will say they did not volunteer to be the mental health providers for the U.S. But because of the upsurge in mental health challenges — the opioid epidemic and so on — they have become the default mental health care providers. So, there’s obviously a role for decarceration and improving mental health in the community.
But there’s also a role for providing support to sheriffs. The accreditation process is like a game plan: This is what you should be doing; this is what good care looks like. And this is how you translate those inputs into outputs. We subsidized the accreditation process for these facilities. We didn’t think the subsidy would be that crucial for obtaining accreditation. It’s about $5,000 to $10,000 for these small and medium-sized jails, which is the majority of jails in the United States. But just that amount of money is quite challenging to reallocate and budget for. We’re talking about county budgets, which are not always very fungible. So, this subsidy was really a facilitator for them becoming accredited.
What should policymakers and law enforcement learn from this research?
YANG: The main takeaway is that obtaining accreditation from the National Commission on Correctional Health Care is highly cost effective. It saves lives and might also have benefits for community safety given that we find suggestive reductions in recidivism. These findings might be important for a sheriff or local county official who hasn’t heard about accreditation but wants to minimize deaths, which will, in turn, minimize their litigation and liability risk, something sheriffs care a lot about. Sheriffs also care about community safety, and so, if recidivism is lower as a result of obtaining accreditation, that can be another attractive benefit.
ALSAN: Coming from a public policy standpoint, the federal government can affect the budget constraints of the states. It can provide subsidies; it can provide incentives for jails to take certain actions. Staffing is an issue — some jails don’t even have the staff to fill out the forms to get accredited.
So many systems have failed the people who find themselves arrested and in jail. Many of the men arrested have never seen a dentist. And so, there’s a level of frustration. Ninety to 95 percent of these people are going back into their communities. Why are we not using this as an opportunity for rehabilitation, for treatment, for screening? And that’s not even in our cost-benefit estimate; we’re just talking about the value of a statistical life. We’re not even including the potential prevention of community-based spread of different types of habits, different types of diseases, or just of despair. These are human beings. Not only that, they’re your neighbors.
Health
The brain’s gatekeepers
Differences in neuronal activation in mice with intact immune cells called regulatory T cells or Tregs (left) and depleted Tregs (right). The finding demonstrates that Tregs play a role in ensuring healthy neuronal activity under normal conditions. Credit: Mathis/Benoist Lab
Ekaterina Pesheva
HMS Communications
January 28, 2025
6 min read
HMS research IDs special cla
Differences in neuronal activation in mice with intact immune cells called regulatory T cells or Tregs (left) and depleted Tregs (right). The finding demonstrates that Tregs play a role in ensuring healthy neuronal activity under normal conditions.
Credit: Mathis/Benoist Lab
Ekaterina Pesheva
HMS Communications
6 min read
HMS research IDs special class of cells that safeguard immunity and memory, and may one day treat neurodegenerative disease
Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of infection, these so-called Tregs keep the immune system from going into overdrive and mistakenly attacking the body’s own organs.
Now scientists at Harvard Medical School have discovered a distinct population of Tregs dwelling in the protective layers of the brains of healthy mice, and their repertoire is much broader than inflammation control.
The research, published Tuesday in Science Immunology, shows that these specialized Tregs not only control access to the inner regions of the brain but also ensure the proper renewal of nerve cells in an area of the brain where short-term memories are formed and stored.
The research, funded in part by the National Institutes of Health, represents an important step toward untangling the complex interplay of immune cells in the brain. If replicated in further animal studies and confirmed in humans, the research could open up new avenues for averting or mitigating disease-fueling inflammation in the brain.
“We found a thus-far-uncharacterized, unique compartment of regulatory T cells residing in the meninges surrounding the brain and involved in an array of protective functions, acting as gatekeepers for other immune cells and involved in nerve cell regeneration,” said study senior author Diane Mathis, the Morton Grove-Rasmussen Professor of Immunohematology in the Blavatnik Institute at HMS.
The work adds to a growing body of research showing that Tregs go above and beyond their traditional immune-regulatory duties and act as tissue-specific guardians of health, the researchers said. Earlier work led by Mathis showed that Tregs in the muscles get activated during intense physical activity to fend off exercise-induced inflammation and maintain muscle health.
“The Tregs that we found in the meninges are endowed with skills customized to fit the needs of this particular tissue,” said study lead author Miguel Marin-Rodero, a doctoral student in the immunology program at Harvard Medical School in the Benoist-Mathis lab. “These findings are consistent with other studies showing that Tregs turn on and off specific genes to match the identity and needs of the organ they reside in — they are really the best immune cells ever.”
Illustration of the three protective layers under the skull.
Hank Grebe, 2018/Getty Images
Tregs dwelling at the brain border act as gatekeepers
The meninges, three protective tissue layers under the skull, shield the brain and spinal cord from injury, toxins, and infection. This brain border hosts a diverse population of immune cells. Most of these cells are innate, and their roles and functions have been fairly well defined. But the brain border is also home to adaptive immune cells, many of which develop after birth, whose roles in brain immunity have remained somewhat elusive. The new study provides a detailed profile of Tregs — a type of adaptive immune cell — at the body-brain interface.
To understand the role of Tregs in this context, the researchers used a genetic technique to deplete them from the meninges of mice. The meninges of animals lacking Tregs produced higher than normal levels of an inflammatory chemical called interferon-gamma, causing widespread inflammation of the meninges. The removal of Tregs also opened the brain’s inner regions to interferon-producing, inflammation-fueling immune cells and activated immune cells that reside nearby but are normally kept at bay by Tregs. No longer restrained by Tregs, these immune cells infiltrated the brain and caused widespread inflammation and tissue damage. The resulting inflammation, the researchers said, was reminiscent of the damage and immune-cell activity seen in human and mouse brains with Alzheimer’s disease.
“These experiments demonstrate that Tregs in the meninges act as gatekeepers to guard the innermost regions of the brain,” Marin-Rodero said.
Absence of Tregs scars a memory-making region of the brain
Next, researchers examined the effect of depleting Tregs on various brain regions. Not all brain regions were affected equally. In the absence of Tregs, inflammatory cells clustered mostly in the hippocampus, an area of the brain involved in learning, memory formation and storage, and spatial navigation. The hippocampus is also one of few regions in rodent and human brains that continues to produce neurons into adulthood, so an assault on this area could have repercussions for memory formation.
Neural stem cells in the hippocampus underwent the most dramatic changes as a result of Treg depletion. These cells are critical because they are capable of becoming many other specialized brain cells. But in the absence of Tregs, their ability to differentiate into other cells was critically hampered. Their activity slowed down or altogether ceased, and they started to die off.
Treg depletion appeared to leave a “scar” in the hippocampus, leading to a persistent functional defect in short-term memory formation, the researchers said. Treg-deficient animals developed problems with short-term memory that persisted even months after their Tregs were restored to normal.
But how exactly do Tregs keep other cells in check?
In a final set of experiments, the researchers found that in the brains of healthy mice, Tregs keep inflammation-driving immune cells under control by competing for a shared resource — a growth factor called IL-2. When Tregs were removed, other immune cells were able to gobble up this cellular fuel, multiply quickly, and produce inflammatory proteins.
A pathway to understand and treat neurodegenerative diseases
Inflammation has been long implicated in multiple neurodegenerative diseases, so the question that comes next, Mathis said, is: Do Tregs in human brains play a role in curbing the inflammation that drives these degenerative processes?
Mathis’ team is currently studying this very question using a mouse model of Alzheimer’s disease. Simultaneously, they are also working with colleagues in the neuropathology and neurosurgery departments at Massachusetts General Hospital to investigate this process in human brains with Alzheimer’s.
In recent years, Treg-based therapies have generated excitement about the possibility of using these cells in an organ-specific or tissue-specific manner to treat immune-mediated diseases. These efforts include lab-modified Tregs (CAR-Tregs and T-cell receptor Tregs) as well as the design of therapeutic molecules that could alter Treg function in a precise and site-specific manner.
“Understanding exactly how Tregs perform their protective duties could one day help us design treatments that boost their activity to modulate a wide range of disease processes,” Mathis said.
Additional authors included Elisa Cintado, Alec J. Walker, Teshika Jayewickreme, Felipe A. Pinho-Ribeiro, Quentin Richardson, Ruaidhrí Jackson, Isaac M. Chiu, Christophe Benoist, Beth Stevens, and José Luís Trejo.
The research described in this story was supported by the JPB Foundation, the Spanish Ministry of Science and Innovation, National Institutes of Health, NIH Director’s New Innovator Award, and the Crohn’s & Colitis Foundation. Additional support was provided through HHMI and the Cure Alzheimer’s Fund and by a predoctoral fellowship from the Spanish Ministerio de Economia y Competitividad (Ministry of Economy and Competitiveness).
Nation & World
Need to boost population? Encourage dads to step up at home.
Christy DeSmith
Harvard Staff Writer
January 27, 2025
5 min read
New historical research by economist Claudia Goldin finds link between fertility rates, gender roles
Fertility rates have fallen everywhere outside of sub-Saharan Africa. And they have fallen faster, and dropped even further, in some developed
Need to boost population? Encourage dads to step up at home.
Christy DeSmith
Harvard Staff Writer
5 min read
New historical research by economist Claudia Goldin finds link between fertility rates, gender roles
Fertility rates have fallen everywhere outside of sub-Saharan Africa. And they have fallen faster, and dropped even further, in some developed nations than others.
In a new paper, Claudia Goldin, the Henry Lee Professor of Economics, explains this divergence with a data-tested model that shows gendered and generational conflicts arising with swift economic change. The 2023 Nobel laureate notes countries whose economies grew gradually over the 20th century — including the U.S. and Sweden — now average around 1.7 children born to each woman. However, latecomers to development like Japan, Korea, and Italy average far fewer children.
The study illustrates how women in transitioning modern economies can be especially disadvantaged by traditional gender roles. “Children take time, and that time isn’t easily contracted out or mechanized,” said Goldin in a presentation of the research to the European Central Bank’s Annual Research Conference last fall. “Therefore much of the change in fertility will depend on if men assume more work in the home as women are drawn into the market, particularly if the home has children.
“If they don’t,” she continued, “women will be forced to cut back on something.”
Claudia Goldin.
File photo by Stephanie Mitchell/Harvard Staff Photographer
Her analysis builds upon findings from a 2009 study published in the Journal of Economic Perspectives titled “Will the Stork Return to Europe and Japan?” The paper — by economists James Feyrer, Bruce I. Sacerdote, Ph.D. ’97, and Ariel Dora Stern, Ph.D. ’14 — found birthrates are highest in countries with low-income levels and low female employment. But a surprising pattern was observed in wealthier countries.
“They note that women’s participation in the economy is actually greater in countries with higher fertility,” said Goldin, who is also the Lee and Ezpeleta Professor of Arts and Sciences.
Her paper compares fertility rates in two groups of six countries. The first set — comprised of Denmark, France, Germany, Sweden, the U.K., and the U.S. — saw relatively continuous economic development over the 20th century even with the disruptions of the Great Depression and two world wars. All had reached a total fertility rate of around two children per woman by the 1970s. Not until the 2010s did rates fall below that figure.
The second group — Greece, Italy, Japan, Korea, Portugal, and Spain — developed quickly from the mid-1950s and ’60s after long periods of economic stagnation or decline. Each averaged three children or more per woman in 1970. But all six had dropped below two by the mid-1980s. Most had converged to around 1.3 by the mid-1990s, with Korea being the extreme case. Its total fertility rate for 2022 (the last year included in Goldin’s analysis) was 0.78 children per woman.
Demographers have dubbed the fertility rates of those nations the “lowest-low.”
Total fertility rates for two groups of nations, 1920 to 2022
Source: “Babies and the Macroeconomy”Source: “Babies and the Macroeconomy”
Goldin theorized that families in the second set of countries had been “catapulted” into the modern economy, with less time for adjusting gender norms. Korea, for example, saw incomes quadruple between the 1960s and ’80s, with 30 percent of the population moving from rural areas to urban areas (usually Seoul) over the same period.
“Rapid economic change often challenges strongly held beliefs,” she summarized. “And beliefs change more slowly than economies do.”
Her paper introduces a framework for understanding how such conflicts lead to lower fertility. It assumes that family traditions and beliefs inform a person’s fertility plans. But so do economic conditions observed in young adulthood. This all comes together as couples plan family size, with men putting more weight on factors inherited from previous generations and women acting as “agents of change” by emphasizing economic self-interest.
“It’s not that boys are more traditional than girls; it’s that boys have more to gain from the traditional home,” Goldin explained. “But girls suddenly see that their options have changed. They can get an education. They can go out and work.”
Goldin’s model demonstrates that greater macroeconomic growth from childhood to adulthood means greater generational conflict and wider gulfs between men’s and women’s preferred family size. It assumes that men who contribute more at home have more of an influence on family size. But women’s desires win out when caregiving and other household tasks fall primarily on them.
Goldin’s model demonstrates that greater macroeconomic growth from childhood to adulthood means greater generational conflict and wider gulfs between men’s and women’s preferred family size.
To test her ideas, Goldin started with 100 years of economic and geographic data from all 12 countries. Sure enough, the “lowest-low” nations saw meteoric growth in per-capita gross domestic product, combined with huge rural-to-urban migrations, beginning in the mid-20th century. Meanwhile, GDP charted a slow, steady incline in the first set of countries, with far fewer migrations to big cities.
Time-use surveys, assembled by the Organization for Economic Cooperation and Development, provided Goldin with evidence of gendered divisions of unpaid caregiving and household labor between 2009 and 2019. She uncovered a bigger gap between men and women in the “lowest-low” countries. Women, on average, devoted 3.1 more hours per day to household duties in Japan and three more hours per day in Italy. Compare that with the U.S., where women logged about 1.79 more daily hours on household duties, or Sweden, where the difference was just 0.8 hours.
“The bottom line is,” Goldin said, “countries that saw this very, very rapid increase in standards of living are probably at sub-optimal birthrates.”
The labor economist and economic historian ends by floating a novel solution. The U.S. baby boom, which peaked above 3.5 children per woman in the late 1950s, is the rare example of a wealthy country temporarily increasing its fertility rate. It was accomplished by “glorifying marriage, motherhood, the ‘good wife,’ and the home,” Goldin writes.
Societies that want to encourage more babies today, she suggests, should try venerating fatherhood.
Health
How exactly does ketamine work? New research offers insight.
Marc Duque Ramírez in the lab.Photos by Grace DuVal
Clea Simon
Harvard Correspondent
January 27, 2025
4 min read
Anesthetic growing in popularity as game-changing therapy for severe, treatment-resistant depression
The anesthetic ketamine has become increasingly popular as a treatment for people with severe depression th
How exactly does ketamine work? New research offers insight.
Marc Duque Ramírez in the lab.
Photos by Grace DuVal
Clea Simon
Harvard Correspondent
4 min read
Anesthetic growing in popularity as game-changing therapy for severe, treatment-resistant depression
The anesthetic ketamine has become increasingly popular as a treatment for people with severe depression that resists conventional therapies. A number of studies have documented the drug’s game-changing effects, but scientists have been unsure exactly how it works. Now, a tiny, translucent fish appears to provide important new insights.
Zebrafish, a member of the minnow family popular as a model for neuroscience research and in home aquariums, do not get depressed, exactly. However, when placed in a virtual environment that simulates the lack of forward movement, they do seem to “give up” — that is, they stop swimming.
Researchers have leveraged this behavior, which is reminiscent of persistent traits in human depression, as well as the tiny fish’s see-through body to observe how their tendency to give up changes when ketamine is introduced. In research published last month in the journal Neuron, scientists at Harvard and the Howard Hughes Medical Institute Janelia Research Campus were able to trace the drug’s interaction with an unexpected neural partner.
Alex Chen (left) and Marc Duque Ramírez study the movements of zebrafish.
As in humans, ketamine makes zebrafish “more resilient to this kind of futility,” said Alex Chen, a Ph.D. student in the Engert Lab in Harvard’s Department of Molecular and Cellular Biology and the Ahrens Lab at Janelia, who co-authored the paper.
Most research attention has focused on neurons, said Chen and co-lead author Marc Duque Ramírez, but their team found that supporting cells called astroglia were the ones in play with this fish “depression” and its treatment.
When the fish first perceive they aren’t moving, activity in the astroglia cells ramps up, and the zebrafish begin to swim harder. The astroglia eventually reach a threshold that signals the fish’s neurons to stop swimming. Ketamine, however, appears to overstimulate the astroglia, making them less sensitive. This overstimulation, which occurs through its stimulation of noradrenergic neurons that activate astrocytes (like astroglia), paradoxically calms the “giving up” response, so the fish continues to swim.
“That was definitely a surprise for us,” said Chen. “We knew these cells were involved in the behavior, and so we are wondering whether giving the fish ketamine would affect these cells after the drug is washed out. But we had no idea that the cells would react so strongly to the drug.”
“We expected it to have the opposite effect,” added Duque Ramírez, a Ph.D. student in the Griffin Graduate School of Arts and Sciences who is also in the Engert Lab.
The first 10 seconds show the larval zebrafish at rest. When the pattern changes to one simulating being stuck in place, the ketamine-treated fish struggles at first, but does not give up as easily and is less passive than an untreated fish.
Credit: Duque, Chen, Hsu, et al.
Duque Ramírez explained that the drug alters calcium levels in the cells, blocking increases that usually lead to the “giving up” trigger. “The hypothesis we have is that by causing this hyperactivation of astroglia, it somehow readjusts the system to a new homeostatic set point where it takes a lot more calcium to induce giving up.”
While the study increases understanding of how ketamine works, the light it has shed on the role of astroglia is key.
“Astroglia cells have historically been thought to play more of a passive role in the brain,” said Chen. “More recently we have seen that these cells can act as active signaling partners to neurons. What seems to happen is that the astroglia cells respond to norepinephrine, which is a transmitter that is released in times of stress or high arousal. The effect in fish is that when these astrocytes are activated by norepinephrine, they suppress swimming, and the fish give up.”
But while the reaction sheds light on how ketamine works, the insight does not appear to apply to other drugs.
“We also tested a bunch of other antidepressants,” said Duque Ramírez. “With some of the psychedelic compounds, even though we saw the same effect behaviorally, they didn’t cause this increase in astroglia in calcium. We think that this could suggest that these other drugs are working on parallel pathways, that they might eventually converge into the same targets, but that this effect was very specific to ketamine.”
“Most of the work being done right now on ketamine and other fast-acting antidepressants has focused primarily on their effects on neurons,” said Chen. “It seems possible that by ignoring these other cell types in the brain, it’s been an obstacle in how the field understands how these drugs work.”
This research was partially funded by the National Institutes of Health and the National Science Foundation.
Nation & World
What makes a good teacher?
One skill — arguably the most important for educators — is also hardest to define
January 27, 2025
4 min read
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
Teachers can have a lasting effect on our success later in life. We asked Heather Hill, the Hazen-Nicoli
A series of random questions answered by Harvard experts.
Teachers can have a lasting effect on our success later in life. We asked Heather Hill, the Hazen-Nicoli Professor in Teacher Learning and Practice at Harvard’s Graduate School of Education, what skills a good teacher possesses.
Most scholars would say that a good teacher does three key things: They establish strong, caring teacher-student relationships; challenge students to think, reason, and communicate their ideas; and convey subject matter accurately and clearly.
Good teachers have strong knowledge of their students as individuals — how they think and think about themselves as learners — as well as of their students’ culture and community.
They not only understand the subject matter they teach; they understand it in ways that are particular to their work in a classroom. For instance, they know how to coordinate different definitions of fractions (as a part of a single whole object, as part of a set of objects, and as a point on number line) in ways that help their learners develop a robust understanding of the topic. In the fraction lesson, good teachers know to use Piaget’s theory of cognitive development — that the world becomes gradually more complex as students progress — and what mistakes students will make when solving one-half plus one-quarter.
It’s impossible (believe me, I’ve tried) to identify objectively “good decisions” in classrooms unless you have knowledge of almost everything about the content taught, the students, and the teacher.
Good teachers can solidly explain content to learners, lead whole-class discussions, and set up and manage small-group work. But perhaps one of the most important, but hardest to define, skills is teachers’ decision-making capability.
Knowing what to do or say next during the flow of instruction is never easy, partly because there’s no “one best way” to engage students, present content, or address a student mistake. In fact, what next instructional step works will vary by the teacher’s goals for a lesson, who the kids are, and how those kids are thinking about the content being taught. It’s impossible (believe me, I’ve tried) to identify objectively “good decisions” in classrooms unless you have knowledge of almost everything about the content taught, the students, and the teacher.
The best teachers check all of the above boxes. They can respond smoothly in the moment when students don’t understand material or get distracted. And students in these classrooms not only do better academically, they enjoy school and get excited about learning — in other words, they thrive.
In some places, teaching is very prescribed, which leaves educators unable to use good judgment. This is fine for novices, who need a lot of support, but probably not so fine for experienced teachers, to whom it can be demoralizing.
I often get asked whether good teachers are born or made. While there’s a fraction of educators who are just not a good fit for the job, it’s also true that teachers learn a ton in the first few years. All of this learning shows up quite clearly in student test score data — students of experienced teachers gain a lot more over the course of a year than students of inexperienced teachers.
Good (and bad) teachers also learn a lot from colleagues. Some of this learning can be less than optimal. I once watched one teacher tell another to use a “Tarzan” division worksheet from Pinterest and spent the rest of the day making a mental list of all the ways implementing that worksheet could go wrong. But a lot of teacher collaborative learning is really positive — it’s teachers with more expertise helping others solve all sorts of problems, with well-established benefits for student learning.
And some kinds of formal training can help OK teachers turn into good ones. For instance, in STEM teaching, it benefits student learning when teachers learn how to use curriculum materials. Coaching is relatively effective in helping teachers develop instructional skills, and there are some effective and relatively brief ways to help improve student-teacher relationships, like helping teachers develop empathy for their most challenging learners.
Campus & Community
Boston, Harvard announce affordable housing funding
A 43-unit development at 65 Seattle St. in Allston is one of two Harvard-enabled affordable housing projects to receive funding from the city of Boston.Rendering provided by Urbanica Inc.
Amy Kamosa
Harvard Correspondent
January 27, 2025
4 min read
Nearly 100 units to be created in Allston
Celebrating the funding
A 43-unit development at 65 Seattle St. in Allston is one of two Harvard-enabled affordable housing projects to receive funding from the city of Boston.
Rendering provided by Urbanica Inc.
Amy Kamosa
Harvard Correspondent
4 min read
Nearly 100 units to be created in Allston
Celebrating the funding of more than $60 million to create and preserve affordable housing throughout Boston, Harvard Executive Vice President Meredith Weenick welcomed city leadership — including Mayor Michelle Wu’s chief of staff, Tiffany Chu, and chief of housing, Sheila Dillon — to the Harvard Ed Portal in Allston to announce awards for 12 projects.
“We know that the housing crisis is one of the biggest sources of stress for families in our city, and that’s why every action we need to take creates more housing production and ensures affordability,” Chu said. “The 12 projects receiving funding here today include affordable units for rent and purchase, affordable housing, senior housing, supportive housing, and will be built on both public and private land.”
“At a time when affordable housing need has never been greater, these awards are an important step forward,” said Weenick. “We’re proud to partner in this effort, and I want to recognize that it takes a village to support these types of projects. All of you have so many partners, including the city, and we’re lucky to have such terrific partners all across our neighborhood.”
“At a time when affordable housing need has never been greater, these awards are an important step forward.”
Meredith Weenick, Harvard executive vice president
Meredith Weenick.
Photos by Veasey Conway/Harvard Staff Photographer
Once complete, the funded projects will provide 637 units of income-restricted housing in the neighborhoods of Allston, Brighton, Chinatown, Dorchester, Fenway, Jamaica Plain, Mattapan, Mission Hill, and Roxbury.
The Harvard-enabled Allston projects included in this funding announcement are the creation of 43 affordable homeownership units on land donated by Harvard at 65 Seattle St. in Allston, and the transformation of the historic Hill Memorial Baptist Church on North Harvard St. into 49 affordable rental units for Boston seniors. Harvard contributed $4.8 million to fully fund site acquisition for the latter.
“As a longtime member of the Allston-Brighton community, Harvard has developed a complex housing strategy that adapts to the dynamic needs of city requirements and city residents,” Weenick said. “And we are excited to be involved in enabling two of the projects that will be announced today. These two projects represent nearly 100 units of affordable housing in Allston and they exemplify what we can activate through creativity, responsiveness, and partnership.”
Harvard’s efforts beyond the campus in Allston already have enabled more than 1,300 new housing units, approximately 25 percent of which are affordable. Harvard donated land at the former site of Brookline Machine at 90 Antwerp St., enabling the creation of 20 homeownership units, 12 of which are affordable. Through regulatory agreements associated with construction of the Enterprise Research Campus, Havard has committed $25 million over 12 years to support affordable housing creation in the neighborhood and will ensure that 20 percent of the residential units in the ERC are affordable.
Additionally, the Harvard-funded All Bright Homeownership Program supports homeownership stabilization in Allston-Brighton by enabling the Allston Brighton Community Development Corp. to purchase and resell homes with deed restrictions to ensure housing remains owner-occupied. On a regional scale, the long-standing Harvard Local Housing Collaborative has funded more than $20 million in low-interest revolving loans since its creation in 2000, helping create and preserve more than 7,000 units of affordable housing in Greater Boston.
According to Boston officials, all of the new construction projects funded in this round will be required to follow the Zero Emissions Building requirements outlined in the MOH Design Standards, and new developments will use electricity and on-site solar panels as the sole (or primary) fuel sources.
Expressing appreciation for the award recipients, Dillon remarked, “You responded to our request for proposals and our funding awards, because you seized an opportunity out there. You saw a great development idea. You put together quality applications. You agreed to make your developments carbon-neutral, and have made commitments to ensure that local businesses, local Boston businesses, are benefiting from this economic activity. Your housing developments will not only house our residents, but they’ll contribute to Boston’s climate goals and economic equity goals, so thank you for all that you have done through this funding round.”
“We’re delighted to celebrate this milestone with all of you. The announcement of these awards is not just financially significant, but is a testament to the hard work and dedication of everyone involved in the effort to create and preserve housing throughout the city of Boston,” stated Weenick.
Work & Economy
How to avoid really bad decisions. (Hint: One tip is just hit pause.)
Business ethicist details ways to analyze complex, thorny issues, legal gray areas, and offers advice we can all use
Christina Pazzanese
Harvard Staff Writer
January 24, 2025
7 min read
Joseph Badaracco.Photo by Susan Young
The business world is certainly no stranger to executives who either intention
How to avoid really bad decisions. (Hint: One tip is just hit pause.)
Business ethicist details ways to analyze complex, thorny issues, legal gray areas, and offers advice we can all use
Christina Pazzanese
Harvard Staff Writer
7 min read
Joseph Badaracco.
Photo by Susan Young
The business world is certainly no stranger to executives who either intentionally or accidentally cross ethical or even legal lines.
Take, for instance, the cases of Sam Bankman-Fried and Elizabeth Holmes.
Bankman-Fried was convicted in 2023 of financial crimes after the collapse of FTX, the high-profile cryptocurrency exchange he founded and ran. Holmes’ tech startup, Theranos, sold home blood testing devices that never worked. She is now serving a prison sentence for defrauding investors out of millions.
These cases are, of course, outliers. The vast majority of business leaders routinely make sound, ethical, and legal calls for their firms. But they do face challenges, and it takes a solid process to work through the complexities of many decisions, says Joseph Badaracco, John Shad Professor of Business Ethics at Harvard Business School.
Badaracco has been teaching M.B.A. students and business leaders for 30 years. His work led to the launch of the School’s first required ethics course in 2004. The Gazette asked Badaracco about how business ethics have changed and to offer some decision-making strategies. Interview has been edited for clarity and length.
How has the definition of business ethics changed over the last 30 years?
When I got started, a lot of business ethics was essentially applied moral philosophy. So, you would teach students the basics of utilitarianism or deontology, and maybe some Aristotle, and then apply that to particular problems.
I think that approach has faded. Certainly, the philosophical concepts are still important, but this idea of top-down application has faded.
At HBS, we approach things in more of a bottom-up way. We focus on the problem, the circumstances, the situation, and then we ask what ethical and practical perspectives are going to be helpful in figuring out what’s right in this situation? So that would be one shift.
Secondly, things are much more in flux now. So many more ethical issues are now in a context that’s international compared to, say, 30 years ago. And then, you’ve got these big technological transitions like AI and robotics and trying to figure out what the ethical implications of that are for your workforce and intellectual property. If you are a student, there’s the question of how do you use AI? What is your work and what isn’t?
One other thing I’m writing about now: During much of the last century, there was much more of a sense of a company as an independent economic unit competing in markets. It had some rules, laws, and regulations that it had to follow. And the major question was: How much, if at all, should executives pay attention to the stakeholders as opposed to the shareholders?
Now, so many companies are enmeshed in really complicated relationships with other organizations — through their IT systems, because societies have delegated so many social responsibilities to companies (clean the air, keep the workplaces safe, hire fairly, and things like that). Companies, in response, have become much more politically active and sophisticated, and they’re much more involved in all these complex relationships with regulators, interest groups, state, local, federal.
“Our minds are a kind of black box, and what matters is what we put into the box as we get ready to make a decision.”
Are the ethical challenges themselves different today than they once were?
When an executive or a manager or even a young manager from an M.B.A. program is trying to figure out what’s right, their accountability is much more complicated because of all these different groups they’re enmeshed with.
When they try to figure out what’s really important in a situation: What are the critical facts? What are the risks? What are the expert opinions? That is vastly more complicated. They also have different legal and ethical responsibilities to all these groups. And then, when they have to think about what is practical, that becomes even more complicated, as well.
So, there’s an open-endedness to the fundamental managerial questions of what’s important, what’s responsible, and what’s practical, that just wasn’t there a couple decades ago.
In a recent paper, you say that good and bad judgments are not black or white, they exist along a spectrum, and that making ethical decisions more closely resembles aesthetic or artistic judgments rather than statistical or logical conclusions. If it’s more art than science, how can those striving to act ethically be confident that’s what they’re, in fact, doing?
There are two kinds of problems, that is, two kinds of questions and decisions. Sometimes there are black-and-white lines. Sam Bankman-Fried may not have been sufficiently aware of them, but he crossed the lines and so did some of his fellow executives.
There is right and wrong, legal and illegal, and it’s hazardous to even get close to those lines because you may stumble across them, and if you’re a leader at any level, the people working for you may think, “Let’s see how close to the line, just like our boss.”
Then there are other complex issues we call “gray areas.” One obligation conflicts with another, or there’s just so much uncertainty you’re not sure what the key facts are. This is where personal judgment plays a much bigger role.
So, how do you know you’re doing something responsible? A lot of it has to do with how you approach the decision. If you have thought in depth and carefully about what really matters in the situation, about your central responsibilities, and what will work, you’ve loaded the dice in favor of a responsible, practical decision.
How do decision-makers get around the problem of seeing beyond their own cognitive biases to avoid making self-serving decisions that are potentially unethical or illegal, particularly in situations that are full of gray areas?
What may have happened at FTX and has happened in a lot of other cases is somebody takes something that’s black-and-white, legal or illegal, and they say, “Wait a minute. It’s not really clear.” That’s a dangerous activity, and that can certainly be done in self-serving ways.
But with a gray problem, there really isn’t a clear right decision. If there was, you wouldn’t be struggling with it, the people you work with might not be disagreeing with you on it. A lot of biases can come into play with gray-area decisions.
So, one question is: Have you tried to wring the biases out by working with other people and focusing sharply, honestly, and analytically on what matters, what is responsible, and what is practical? This will help you make the best decision you can.
But we are inevitably influenced by all sorts of factors, conscious and unconscious. In the end, you want to be able to feel that you have done all you can to make a sound, responsible decision, but with gray-area problems, there are no guarantees.
It’s one thing to make an ethical decision based on facts laid out in a book or case study, but quite another to do so while surrounded by outside factors and changing circumstances. How do people prevent these things from obscuring the best way forward?
I wrote a book a number of years ago about reflection, based on in-depth interviews with 100 executives and managers. I discovered that almost everybody had some way of reflecting. It took all different forms: driving to work, exercising, sitting quietly and looking out the window, talking with someone they trust and respect, and praying. One executive said when he was struggling with a really hard decision, he would put on earphones and listen to some of his favorite Broadway show tunes, and then he would often find that his mind was clearer and he was comfortable making a decision.
My fundamental conviction is decision-making and reflection should be guided by the questions of: What really matters; what are my central responsibilities; and what will work? Then the final question is: What can I live with? Then you decide. I don’t think we really understand how we make these final decisions and judgments. And the current state of neuroscience, our minds are a kind of black box, and what matters is what we put into the box as we get ready to make a decision.
Harvard University Housing (HUH) manages approximately 3,000 apartments, offering a broad choice of locations, unit types, amenities, and sizes to meet the individual budgets and housing needs of eligible Harvard affiliates (full-time graduate students, faculty members, and employees). Harvard affiliates may apply for Harvard University Housing online at www.huhousing.harvard.edu. The website also provides information about additional housing options and useful Harvard and community resources for incoming and current affiliates.
In accordance with the University’s rent policy, Harvard University Housing charges market rents*. To establish the proposed rents for 2025–2026, Jayendu Patel of Economic, Financial & Statistical Consulting Services performed and endorsed the results of a regression analysis on three years of market rents for more than 14,700 apartments. The data on apartments included in the analysis were obtained from a variety of sources, including rentals posted on the HUH Off-Campus Housing website by private-market property owners, information supplied by a real estate appraisal firm, and various non-Harvard rental websites, in order to provide comparable private rental market listings for competing apartment complexes in Cambridge, Boston, and Somerville. As always, all revenues generated by Harvard University Housing in excess of operating expenses and debt service are used to fund capital improvements and renewal of the facilities in HUH’s existing residential portfolio.
The rents noted in this article have been reviewed and endorsed by the Faculty Advisory Committee on Harvard University Housing and will take effect for the 2025-2026 leasing season. Written comments on the proposed rents may be sent to the Faculty Advisory Committee on Harvard University Housing, c/o Harvard University Housing, Richard A. and Susan F. Smith Campus Center, 1350 Massachusetts Ave., Room 827, Cambridge, MA 02138. Comments to the committee may also be sent via email to leasing@harvard.edu. Any written comments should be submitted by Feb. 7.
2025–2026 rents for continuing HUH tenants
Current HUH tenants who choose to extend their lease will receive, on average, a 5 percent rent increase, with actual increases ranging from 0 percent to 6.5 percent. Heat, hot water, electricity, and gas, where applicable, are included in all Harvard University Housing apartment rents; internet service and air conditioning may also be included where available.
Harvard University Housing tenants will receive an email in March 2025 with instructions on how to submit a request to either extend or terminate their current lease. Tenants who would like additional information or help in determining their continuing rental rates for 2025–2026may call the HUH Leasing Office at (617) 495-1459.
2025–2026 rents for new HUH tenants for the 2025-2026 leasing season
The results of this market analysis and of other market research indicate that Harvard University Housing 2025–2026 market rents will be as listed below. Heat, hot water, electricity, and gas, where applicable, are included in all Harvard University Housing apartment rents; internet service and air conditioning may also be included, where available.
Haskins Hall: studios $2,364–$2,460; one bedrooms $2,628–$2,904.
Holden Green: one bedrooms $2,508–$2,880; two bedrooms $2,880–$4,056; three bedrooms$3,768–$3,852.
2 Holyoke Street: one bedrooms $2,856–$3,024.
Kirkland Court: one bedrooms $2,532–$3,000; two bedrooms $3,336–$3,588; three bedrooms $4,296–$4,596.
8A Mt. Auburn Street: one bedrooms $2,856–$3,024.
Peabody Terrace: studios $2,316–$2,976; one bedrooms $2,796–$3,312; two bedrooms $3,228–$3,852; three bedrooms $4,740–$5,160.
16 Prescott Street: studios $2,316–$2,472; one bedrooms $2,676–$2,880.
18 Prescott Street: studios $2,256–$2,328; one bedrooms $2,664–$2,928.
85–95 Prescott Street: studios $2,376–$2,628; one bedrooms $2,688–$3,132; two bedrooms $3,144.
Shaler Lane: one bedrooms $2,544–$2,736; two bedrooms $2,904–$3,444.
Soldiers Field Park: studios $2,772–$3,264; one bedrooms $3,192–$3,648; two bedrooms $3,912–$4,932; three bedrooms $4,332–$5,668; four bedrooms $5,688-$5,856.
Terry Terrace: studios $2,448–$2,532; one bedrooms $2,700–$3,000; two bedrooms $3,336–$3,372.
9–13A Ware Street: studios$2,352–$2,496; one bedrooms $2,664–$2,988; two bedrooms $3,324–$3,348.
15 Ware Street: studios $2,580; one bedrooms $3,504; two bedrooms $4,080.
19 Ware Street: two bedrooms $3,876–$3,924; three bedrooms $4,164.
One Western Avenue: studios $2,532–$2,820; one bedrooms $2,724–$3,180; two bedrooms $3,192–$3,984; three bedrooms $4,608–$4,980.
Wood Frame Buildings: studios $1,728–$2,448; one bedrooms $2,496–$3,468; two bedrooms $3,132–$4,800; three bedrooms $3,504–$6,384; four bedrooms $5,400–$6,000.
The comments received will be reviewed by the Faculty Advisory Committee, which includes: Suzanne Cooper, Edith M. Stokey Senior Lecturer in Public Policy, Harvard Kennedy School; Nancy Hill, Charles Bigelow Professor of Education, Harvard Graduate School of Education; Howell Jackson, James S. Reid Jr. Professor of Law, Harvard Law School; Jerold S. Kayden, Frank Backus Williams Professor of Urban Planning and Design, Graduate School of Design; John Macomber, Gloria A. Dauten Real Estate Fellow, senior lecturer, Harvard Business School; Daniel P. Schrag, Sturgis Hooper Professor of Geologyand Professor of Environmental Science and Engineering, Faculty of Arts and Sciences; and Sean Caron, vice president for Campus Services (chair), Office of Executive Vice President for Administration.
*The rents for tenants of Harvard University Housing are set at prevailing market rates, in keeping with the University’s affiliated housing rent policy. This policy was established in 1983 by President Derek Bok based on recommendations from a study led by Professor Archibald Cox and the Committee on Affiliated Housing. The original faculty committee determined that market rate pricing was the fairest method of allocating apartments and that setting rents for Harvard University Housing below market rate would be a form of financial aid, which should be determined by each individual School, not via the rent setting process. Additionally, the cost of housing should be considered when financial aid is determined.
Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Harvard partners with national nonprofit to recruit high-achieving low-income students
First QuestBridge Scholars will matriculate in fall 2026
January 23, 2025
2 min read
Harvard University has announced a new partnership with QuestBridge, a national nonprofit program that connects high-achieving students from low-income backgrounds wi
Harvard partners with national nonprofit to recruit high-achieving low-income students
First QuestBridge Scholars will matriculate in fall 2026
2 min read
Harvard University has announced a new partnership with QuestBridge, a national nonprofit program that connects high-achieving students from low-income backgrounds with top liberal arts colleges and research universities with a promise of full financial aid for four years. This new effort, said Dean of Admissions and Financial Aid William Fitzsimmons, will help strengthen Harvard Admissions’ outreach to recruit the most exceptional students from a broad range of backgrounds and experiences.
“The Harvard College Office of Admissions and Financial Aid is committed to bringing the most promising students to Harvard from all socioeconomic backgrounds. We are excited to partner with QuestBridge,” said Fitzsimmons. “We look forward to working together to attract the nation’s brightest students from low-income backgrounds and enhancing our efforts to provide educational opportunities to talented students everywhere.”
“Harvard’s world-class financial aid allows any talented student to attend, if admitted, and our relationship with QuestBridge greatly expands our reach around the country.”
Jake Kaufmann, Griffin Director of Financial Aid
Beginning in the fall, Harvard will be part of the QuestBridge National College Match program, a college and scholarship application process that matches QuestBridge’s finalist students with admission and four-year scholarships to its college partners. Finalists can list up to 15 partner institutions during the match process, and typically receive match results in early December. Finalists who do not match with any institutions may then apply to any college or university through their regular-decision programs. Harvard’s first QuestBridge Scholars will matriculate in fall 2026.
“QuestBridge has created an attractive program for extraordinary high school students from less-resourced families to navigate the application process at many top colleges. We hope that by joining QuestBridge, we have created another compelling opportunity to consider Harvard,” said Director of Admissions Joy St. John.
“Harvard’s world-class financial aid allows any talented student to attend, if admitted, and our relationship with QuestBridge greatly expands our reach around the country,” said Jake Kaufmann, Griffin Director of Financial Aid.
“We are delighted that Harvard College has joined the QuestBridge partnership. A campus dedicated to the power of a liberal arts and sciences education that strives to educate citizen-leaders is an excellent place for our scholars to call home,” said Ana Rowena Mallari, co-founder and CEO of QuestBridge.
For more information about how Harvard works with QuestBridge, visit our Admissions page.
Jodie Foster.
Campus & Community
Jodie Foster to receive Radcliffe Medal
Will be recognized for her barrier-breaking career
January 23, 2025
2 min read
Academy Award-winning actress and filmmaker Jodie Foster will receive the Radcliffe Medal on May 9, the Harvard Radcliffe Institute announced Thursday.
Each year, the institute awards the medal to an individual who embodies Radcliffe’s commitment t
Will be recognized for her barrier-breaking career
2 min read
Academy Award-winning actress and filmmaker Jodie Foster will receive the Radcliffe Medal on May 9, the Harvard Radcliffe Institute announced Thursday.
Each year, the institute awards the medal to an individual who embodies Radcliffe’s commitment to excellence and impact. The medal was first awarded to Lena Horne in 1987; recent honorees include Sonia Sotomayor, Ophelia Dahl, Sherrilyn Ifill, Melinda French Gates, and Dolores Huerta.
In making its announcement, Radcliffe noted that Foster will be honored for her barrier-breaking career, which has contributed to important progress in an industry that has long been male dominated, inspiring countless individuals in and beyond her field. In addition to her work in front of and behind the camera, she has advanced efforts to improve the safety and well-being of LGBTQ+ young people.
The afternoon program will begin with a panel on the representation of women in film, featuring industry and scholarly perspectives on gender and age stereotypes, role modeling, the role of cinema in illuminating social issues and creating change, and future opportunities for progress and creativity. Following a testimonial, Foster will engage in a keynote conversation with Henry Louis Gates Jr., Alphonse Fletcher University Professor and director of the Hutchins Center for African & African American Research at Harvard University. The program will conclude with the formal award presentation by Tomiko Brown-Nagin, dean of Harvard Radcliffe Institute, and a community reception for all registered in-person attendees.
Additional event and registration details will be available in March. Please note that Radcliffe Day 2025 will occur in advance of Harvard University Commencement Week (May 26–30).
James J. Husson.
Campus & Community
New VP named for alumni affairs and development
James J. Husson returns to Harvard to succeed Brian K. Lee this spring
January 22, 2025
4 min read
James J. “Jim” Husson has been appointed the new vice president for alumni affairs and development, President Alan Garber announced Wednesday.
“An accomplished and admired leader in the field of advancement, Jim has d
James J. Husson returns to Harvard to succeed Brian K. Lee this spring
4 min read
James J. “Jim” Husson has been appointed the new vice president for alumni affairs and development, President Alan Garber announced Wednesday.
“An accomplished and admired leader in the field of advancement, Jim has devoted his career to strengthening institutions through both philanthropy and engagement,” said Garber in a message to the Harvard community. Garber praised “Jim’s curiosity and humility, as well as his belief in universities as a force for social good. These qualities and others will serve him well as he works to strengthen the University at a critical moment for all of American higher education.”
Husson brings more than three decades of leadership in higher education to the role. Currently serving as vice president for development and alumni relations at the University of Pennsylvania, Husson got his start in higher education at Harvard and has developed over the years a strong record of fostering engagement with alumni and driving successful, cross-university fundraising initiatives.
“I’m thrilled to be returning to Harvard, a place that was my professional home for much of my early career and that continues to inspire me. Harvard’s role in higher education has never been more important, and its extraordinary alumni community — through their commitment, engagement, and generosity — will be essential partners in advancing the University’s academic and societal mission,” said Husson.
In his new role, Husson will oversee the University Development Office, Faculty of Arts and Sciences Development, and the Harvard Alumni Association. Husson will officially assume his duties on April 1.
“I’m deeply grateful to President Garber for this opportunity to join his leadership team. I look forward to working with Harvard’s dedicated alumni affairs and development professionals to ensure that the University remains a beacon of excellence, innovation, opportunity, and global impact for generations to come.”
Prior to Penn, Husson oversaw development and alumni relations at Boston College (BC), where his two-decade tenure included the then largest philanthropic campaign in that institution’s history. BC’s Light of the World campaign raised $1.6 billion, enabling enhanced financial aid and current-use scholarships along with the creation of over three dozen professorships, and 10 major research centers including the Shea Center for Entrepreneurship, Rappaport Center for Law and Public Policy, and McGillycuddy-Logue Center for Undergraduate Global Studies. The campaign also played an important part in the expansion of the University’s campus, with significant gifts supporting the construction and renovation of numerous buildings and facilities.
At Harvard, Husson served in various development roles across the University. He began his career in higher education as director of annual giving at the Graduate School of Design in 1989. He also held leadership roles in the Faculty of Arts and Sciences and the University Development Office, including as director of major gifts during the University’s then-record-breaking $2.6 billion capital campaign in the 1990s. Between Harvard and Boston College, Husson oversaw development at Brown University.
A prominent leader in the field of advancement and alumni affairs, Husson served on the faculty and as chair for the Council for Advancement and Support of Education (CASE) Summer Institute in Educational Fundraising. Husson’s exceptional teaching skills have been recognized by his peers with CASE’s Crystal Apple Award for Teaching Excellence.
Husson’s appointment concludes the search to replace Brian K. Lee, who has served as vice president since 2018 and announced in July that he would step down. Lee will continue in his current role through the end of March. “With customary generosity and grace, Brian has offered to see the University through this important leadership transition,” said Garber. “I join countless others in thanking him for his extraordinary contributions to our mission and to our community.”
Garber also expressed gratitude to members of the community who advised on the search. “The excellent result of our search process was guided by the perspectives and insights of individuals throughout our community,” he said. “I am grateful to everyone who devoted time and attention to this effort, especially the members of our search advisory committee.”
A native of Lowell, Massachusetts, Husson is a first-generation college graduate whose grandparents immigrated from Greece and Lebanon in the early 20th century. He is a grad of the University of Rochester and Northfield Mount Hermon School, where he also began his career in philanthropy as an annual giving officer. Parents of two adult children, Husson and his wife are longtime residents of Arlington, Massachusetts.
Health
New study maps the ‘dental deserts’ in the U.S. — and there are lots of them
Harvard research shows 1.7 million lack access to care
Heather Denny
HSDM Communications
January 22, 2025
4 min read
Imagine having to travel for hours for a routine dental cleaning or wait days to get treatment for a toothache. For nearly 1.7 million people in the U.S., this is a reality.
A new study
New study maps the ‘dental deserts’ in the U.S. — and there are lots of them
Harvard research shows 1.7 million lack access to care
Heather Denny
HSDM Communications
4 min read
Imagine having to travel for hours for a routine dental cleaning or wait days to get treatment for a toothache. For nearly 1.7 million people in the U.S., this is a reality.
A new study published in JAMA Network Open takes a look at the issue of access to dental care, using a more nuanced approach to identify areas with limited dental services across the U.S.
Led by Hawazin Elani, assistant professor in oral health policy and epidemiology at Harvard School of Dental Medicine, the study is one of the first to map spatial accessibility to dental clinics nationally at a granular level. By analyzing data at the block group level — the smallest geographical unit used by the U.S. Census Bureau defined by clusters of blocks — the researchers provide a more detailed picture of dental care access, revealing significant disparities within specific geographic areas of the country.
“These areas are really ‘dental deserts’ where you’d have to go to great distances to find a dentist. Our findings highlight a concerning geographic maldistribution of dentists, with many rural and disadvantaged communities left without access to care,” Elani said.
The study’s approach builds on existing efforts to understand dental care access, including the Health Resources and Services Administration’s designation of Health Professional Shortage Areas for dental services, but takes it a step further by using an advanced gravity-based method to assess the availability of clinicians, accessibility, and adjustments for demand and supply factors at the block group level.
“We were able to identify areas with limited access to dental care that may have been missed by previous studies,” said Md. Shahinoor Rahman, co-author of the study.
This disparity is evident in the ratio of dentists to population, with rural areas having one dentist available for every 3,850 people, compared with urban areas, which have more than 2½ times more dentists, with one dentist for every 1,470 people.
By state, Alaska had the highest percentage of the population (10.4 percent) living in dental deserts, followed by Montana (7.8 percent) and North Dakota (7.7 percent). Only four states — Connecticut, Delaware, Indiana, and New Jersey — along with Washington, D.C., were identified as having no dental deserts.
Elani and her co-authors also examined socioeconomic data to contrast racial and ethnic composition, population by age group, poverty level, educational attainment, median household income, and health insurance. The results showed that nearly 24.7 million individuals lived in dental care shortage areas. In these counties, nearly 15.6 percent of the population lived below the federal poverty level. Racially, more white populations lived in rural areas with a shortage of dentists, as compared with Hispanic and Black populations. However, in urban areas with segregation and a concentration of poverty, Hispanic and Black individuals were likelier to live in areas with a shortage of dental care. A high proportion of individuals in rural shortage areas were also uninsured, and more likely to experience spatial disparities in access to dental care.
Elani noted that this has serious implications for oral and overall health, saying, “The situation is likely even more dire for Medicaid and Medicare beneficiaries, who face additional barriers due to low dentist participation, worsening existing disparities. This can lead to people putting off much-needed care due to access challenges.”
“With this more precise data, we hope our findings can inform dental workforce planning efforts and targeted interventions at the federal and state levels to encourage dentists to practice in underserved areas and reduce disparities in access to dental care,” Elani said.
This work was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health under Award No. R01MD017093.
Cynthia Erivo. Photo by Mark Seliger
Campus & Community
Cynthia Erivo is Hasty’s Woman of the Year
‘Wicked’ star will receive Pudding Pot on Feb. 5
January 21, 2025
2 min read
“Wicked” star Cynthia Erivo has been named the recipient of the 2025 Hasty Pudding Woman of the Year Award, Hasty Pudding Theatricals announced on Tuesday.
From Erivo’s celebrated performances in the film “Harriet” and Broad
From Erivo’s celebrated performances in the film “Harriet” and Broadway’s “The Color Purple” to her recently critically acclaimed role as Elphaba in Universal’s “Wicked: Part One,” the Pudding is proud to celebrate her truly unique and impactful presence in the world of entertainment, said organizers.
Erivo is a Grammy, Emmy, and Tony Award-winning actress, singer, and producer, as well as an Academy Award, Golden Globe, BAFTA, and SAG nominee. Erivo will guest star in the second season of “Poker Face,” Peacock’s critically acclaimed series starring Natasha Lyonne.
“We are holding space for Cynthia Erivo’s arrival,” said Hannah Frazer, Man and Woman of the Year events coordinator. “We’re sweeping out our broomstick closets and prepping some wicked smart humor as we eagerly await her in February. Before she flies off with her Pudding Pot, she’ll have to work a little magic to earn it.”
“Looks like someone might need to hold Cynthia’s hand — or finger — during this roast,” joked Hasty Pudding producer Daisy Nussbaum. “That said, we promise not to be as mean as the wizard. By the end, she’ll be the one who’s truly popular with the crowd.”
The Woman of the Year Award is Hasty Pudding Theatricals’ oldest honor, bestowed annually on performers who have made lasting and impressive contributions to the world of entertainment. Established in 1951, the prize has been given to many notable and talented entertainers including Meryl Streep, Julia Roberts, Scarlett Johansson, Anne Hathaway, Kerry Washington, and most recently Annette Bening, the 74th Woman of the Year. The Hasty Pudding Theatricals is a program of The Hasty Pudding Institute of 1770.
The Hasty Pudding Theatricals will host a celebratory roast for Erivo on Feb. 5 at 7 p.m., after which she will be presented with her Pudding Pot at Farkas Hall, the Hasty Pudding’s historic home in Harvard Square since 1888. A press conference will follow the presentation at 7:20 p.m. Afterward, Erivo will attend a performance of the Hasty Pudding Theatricals’ 176th production “101 Damnations.”
Eric Beerbohm.File photo by Dylan Goodman
Campus & Community
Spreading gospel — and strategies — of productive disagreement
Eric Beerbohm looks back on successes, challenges of first year of new Civil Discourse initiative
Christy DeSmith
Harvard Staff Writer
January 21, 2025
8 min read
Eric Beerbohm believes disagreement — whether with people or texts — fuels research and brings out t
Spreading gospel — and strategies — of productive disagreement
Eric Beerbohm looks back on successes, challenges of first year of new Civil Discourse initiative
Christy DeSmith
Harvard Staff Writer
8 min read
Eric Beerbohm believes disagreement — whether with people or texts — fuels research and brings out the best in teaching. “It’s really the lifeblood of a university,” says the inaugural Alfred and Rebecca Lin Professor of Government.
Beerbohm was engaged with similar work as faculty director of the Edmond & Lily Safra Center for Ethics when Hopi Hoekstra, Edgerley Family Dean of the Faculty of Arts and Sciences, tapped him to lead her new Civil Discourse initiative. The Quincy House Faculty Dean and affiliate with the Department of Philosophy has spent the last year guiding a wide-ranging exploration of strategies to foster more open, respectful dialogue across campus.
“These conversations need to be handled in ways that affirm others with empathetic listening,” Beerbohm said. “As a first step, what we’ve done is to set out the conditions for, model, and then provide opportunities to practice civil discourse.”
As the Civil Discourse initiative enters its second year, we asked Beerbohm about first-year successes and challenges around the effort. He also previewed its next generation of programming. The interview was edited for length and clarity.
What have you learned over the past year about the FAS community’s ability to engage with civility on ethically charged topics?
We’ve learned that many students are eager to jump right in, but they’re not always sure how. In interviews I did with Tomiko Brown-Nagin for the University’s open inquiry report and in the listening sessions David Laibson and Maya Jasanoff led for the FAS Classroom Social Compact Committee, students kept telling us the same thing: They want to speak up in class, but they need clearer norms. They want more explicit frameworks and a better sense of what’s expected when they share deep convictions versus when they offer a knee-jerk conjecture.
And it’s not just students. Faculty and graduate students — myself very much included — bring a lot of smuggled assumptions into the classroom. Many students think that any argument they make will be seen as a deep reflection of who they are. Some believe that disagreeing with peers or professors is rude, when in fact it’s often exactly what good learning looks like. We need to flip that script. Open disagreement isn’t a roadblock; it’s a sign we’re doing our jobs. Helping everyone see that even contentious contributions are welcome and productive has been central to our efforts this year.
“Open disagreement isn’t a roadblock; it’s a sign we’re doing our jobs.”
How exactly can faculty go about setting the explicit frameworks you mentioned?
Some Law School faculty use the Chatham House Rule to create a space for candid discussion, while faculty from other Schools have emphasized co-creating norms with students at the start of the semester.
We’ve hosted several workshops and events where faculty shared the norm-setting strategies they use in their classrooms. One was a webinar featuring Meira Levinson, Archon Fung, and Janet Halley, who shared how they set the tone for open dialogue in their classrooms, offering practical methods like fostering intellectual humility, establishing structured participation guidelines, and modeling respectful disagreement.
The Ethics Center has been collecting these strategies and consolidating them into a database that faculty can draw from to tailor approaches to their teaching needs. We have also modeled constructive engagement through our “Ethics Monday” and “Ethics in Your World” lunchtime talks. These events tackle pressing issues — from legacy admissions to political threats to democracy — using a format that showcases open, structured dialogue. The strong attendance at these sessions shows that our community is eager for better ways to disagree productively.
We are also working with the Bok Center and the Intellectual Vitality initiative to bring innovative tools into classrooms. One of our key efforts involves piloting simulations where teaching fellows tackle challenging scenarios, such as managing a class in which students are reluctant to take on assigned roles. By combining faculty insights, curated resources, and live demonstrations of these techniques, we’re equipping educators with the tools they need to foster inclusive and dynamic discussions in any classroom.
How does this work carry into House life?
We are breaking down walls between the classroom and the House communities, fostering richer, ongoing conversations. For example, in the 800-student course “Justice: Ethical Reasoning in Polarized Times,” many sections met in the Houses just before dinner. This scheduling encouraged debates to spill over into mealtime discussions, creating a seamless flow between academic learning and communal life.
The Ethics Center’s Fellows in Values Engagement (FiVE) program has further deepened this connection. Proctors and tutors have hosted intimate sessions on topics ranging from moral dilemmas in public service to the ethical implications of living forever and questions of animal status and veganism. Looking ahead, they are planning live podcasts in the Houses this spring. Imagine a lively conversation on a hot-button topic unfolding right in a common room — students can watch, jump in with questions, and shape the direction of the dialogue.
What more can we expect in the initiative’s second year?
This fall, Dean Hoekstra assembled an FAS-wide advisory group on civil discourse, which I co-chair with Director of the Bok Center Karen Thornber. We have students, staff, and faculty all working together to scale up last year’s pilot programs. With help from the Harvard Initiative for Learning & Teaching (HILT), we are planning to convene Harvard’s experts on negotiation and facilitation, whose teaching doesn’t always travel beyond our professional Schools. The idea is to connect the dots among the Ethics Center, the Bok Center, the College’s Intellectual Vitality initiative, and the Office of Undergraduate Education. We want to weave civil discourse practices through every layer of campus life.
This spring, we’ll launch two new event series. The first pairs longtime FAS faculty friends who passionately disagree — across disciplines and within them. The second spotlights faculty whose research challenges basic assumptions about disagreement. We’ll learn from poets and social scientists alike, digging into depolarization, exploring the differences between “civil” and “civic,” and even looking at the fight-or-flight neuroscience behind conflict.
We’re also kicking off an interdisciplinary research lab focused on civil disagreement and hosting a February conference to highlight new research and evidence-based practices. Plus, we’ll hold a roundtable on listening — both the theory and the practice.
Were there any public events from year one that you found particularly successful in modeling or inviting civil discourse?
Philosopher Emily McTernan’s talk on “Taking Offense” was a standout. She tackled the tough question of what to do when conversations get uncomfortable. Her message: “Don’t run away. Lean in.”
Another high point was “Who Wants to Be a Trillionaire?” — a panel on extreme wealth featuring scholars with wildly different viewpoints. It got heated, but never crossed the line. The result? A deeper, more illuminating conversation that revealed new insights and strategies.
Which ethically charged topics will you tackle in 2025?
We’ve got a full slate, including the ethical dilemmas raised by social media, the manipulative power of generative AI, and the nuances of academic freedom. We look for issues that don’t fit neatly into left/right binaries but instead open space for unexpected agreements and creative solutions. Curiosity and empathy will remain at the core, along with the know-how to push back constructively when we disagree.
This year, we’re also piloting a new format inspired by the original PBS “Ethics in America” series at Harvard Law School. In this approach, a moderator will guide participants through a labyrinth of ethical dilemmas, assigning roles — sometimes unsettling ones — on the spot. A journalist might find themselves stepping into the shoes of a legislator, or a student might be asked to think like the dean of the College.
Our belief, supported by robust research, is that the ability to engage in empathetic disagreement is like a muscle — it grows stronger with deliberate practice. These kinds of scenarios, where participants are challenged to inhabit new perspectives and make tough calls, provide exactly that kind of exercise.
I see you have a new title — Alfred and Rebecca Lin Professor of Government — named for two alumni who specifically set out to support civil discourse.
I’m honored and grateful. It shows how closely my scholarship has merged with this initiative. With support from this professorship, I planned to write a book about how formal parliamentary rules can be misused to manipulate decisions. But after a year of watching how people navigate tough topics in classrooms and House lounges — even testing ideas with Quincy House students in their weekly Big Questions gathering — I’m starting at a more personal level: everyday disagreements among friends and family. The working title is “How to Disagree.” It will draw on all the lessons we’re learning here and hopefully help foster a braver, more open discourse culture far beyond Harvard’s gates.
Arts & Culture
How maps (and cyclists) paved way for roads
Sy Boles
Harvard Staff Writer
January 21, 2025
6 min read
Map of the road from Dublin to Wexford, circa 1845. Courtesy of Harvard Library
Curator takes alternative route through cartographic history and finds a few surprises
Today many people would be lost without the interactive, highly mathematical GPS maps that we carry in
Map of the road from Dublin to Wexford, circa 1845.
Courtesy of Harvard Library
Curator takes alternative route through cartographic history and finds a few surprises
Today many people would be lost without the interactive, highly mathematical GPS maps that we carry in our pockets. But entire traditions of mapmaking exist outside the norms of latitude and longitude, from routes drawn in sand to itineraries for early traders to topographical guides for the earliest hobby cyclists.
“Rivers & Roads: The Art of Getting There,” an exhibit on display through Jan. 31 in the corridor gallery of Pusey Library, explores methods of mapmaking “that don’t adhere to this latitude and longitude system but are still very effective,” said curator Molly Taylor-Poleskey, Harvard Map Librarian. Taylor-Poleskey spoke to the Gazette about what these unusual maps can tell us about how we think about getting from here to there. This interview was edited for length and clarity.
What inspired you to focus on maps that don’t rely on a grid system?
There is a Western tradition of mathematical mapping that undergirds digital wayfinding like what you have on your Google Maps. Other ways of saying this are Cartesian, universal, or Ptolemaic maps, from the ancient Greek mathematician who came up with the idea of placing an imaginary grid over the globe from which you could measure one point to another.
Molly Taylor-Poleskey, Map Librarian at Harvard Library.
Veasey Conway/Harvard Staff Photographer
But that’s only one kind of distance, and it’s not the way that I think about distance when I move around in my everyday life. I think, “OK, I’m going to bike to work today. Where are the hills, where’s the dangerous intersections?” Mapping throughout time and in different cultures has approached the question of getting around in so many ways, but we’ve become so used to thinking about mapping in this one way.
We’ve had this idea about accuracy that goes along with math as universally and completely objective. I wanted to say, it’s not objective. A lot of the maps in this exhibit are hyperlocal, and they need to be seen in their contexts to understand what they’re trying to accomplish. I wasn’t interested in the global worldview; it’s really about communication between the mapmaker and the map user. What I found in the process of curating the exhibit was a beautiful variety of ways of doing that.
Sultan Bello’s Map of the Niger River’s Course, 1826, misrepresents the river.
Courtesy of Harvard Library
You have on display a map of the Niger River, published in 1826, that was originally drawn in the sand by Muhammad Bello, Sultan of the Sokoto Caliphate, for a British explorer named Hugh Clapperton. You say it’s believed that Bello purposefully misrepresented the river to discourage Europeans from further exploration of the area. What does that tell us about the balance between objective and objectivity in these hyperlocal maps?
Mapmakers are always selective. In that particular map, we know Sultan Bello is giving some misinformation about something he knew quite intimately. We can conjecture about the things he wanted to hold back. Maps are about control of information, so there’s a specificity about what’s useful and what’s not.
I’ll also say that the question of objectivity comes up in another way in the history of mapmaking. Western maps in a certain era would say “There be monsters here,” and that was code for “We don’t know, and what we don’t know is dangerous.”
There’s a switch in about the 19th century in Western maps where you stop seeing what today we think of as ornamental elements. That’s because there’s this idea that people have conquered nature, and it’s not so scary.
What other themes emerged as you put together this exhibit?
Roads started appearing in European maps much later than I would have thought, not until the 17th century. I was curious about what Europeans used for wayfinding before that, and I discovered it was itineraries. It came out of the medieval pilgrimage tradition. You’d convey the route from one place to another by listing the places along the way. In the early modern period, merchants created itineraries showing the routes connecting sites of production to market cities. Those maps didn’t have political boundaries because you didn’t need them. That’s a different perspective than we get 100 years later in the 17th century when rulers were making state-sponsored maps.
Also, maps don’t just document roads: In a way, they led to the development of roads themselves. In the late 19th century, we have a huge transition. For the first time, there was a middle class in Europe and America that had money and time for leisure activities. At the same time, bicycles become safer and massively popular. You have a lot of newly urban people who are venturing out to enjoy the countryside recreationally. So how do they know how to get around? There are no road signs. This vogue for excursions into the countryside led to the development of route maps that you could fold up and put in your pocket. We have a map of bicycle routes in Paris that shows elevation change because you want to know when you’re going to have to push. It’s so interesting to me because it has some features like a GPS navigation system would have today that say, “turn left,” or “straight ahead.” It’s just one little instruction because you are simultaneously navigating and riding and do not want to be distracted by extraneous information.
Bicycle routes near Paris, circa the early 20th century.
Courtesy of Harvard Library
Hobby cyclists would find themselves lost or broken down with no information about where they were or where they could get help, and the roads were almost all unpaved. So they became huge road advocates. We have an 1888 cyclists’ road book from Connecticut, the first modern tourist guidebook. It was made by the League of American Wheelmen, and they had a campaign for marking roads and systematizing them. That kind of advocacy work in government and through their publications is copied by automobile associations right afterward, which become democratized shortly after. Organizations like the American Automobile Association, AAA, took on the same methods of advocacy starting in the 1920s. It was largely thanks to the Good Roads bicycle movement that early motorists had any passable roads to travel through the American countryside.
A visitor examines a map during a tour of “Rivers & Roads: The Art of Getting There.”
A team led by Kang-Kuen Ni (center), including Gabriel Patenotte (left) and Samuel Gebretsadkan, among others, successfully trapped molecules to perform quantum operations for the first time. Photo by Grace DuVal
Science & Tech
Researchers make leap in quantum computing
Yahya Chaudhry
Harvard Staff Writer
January 21, 2025
5 min read
Trapping molecules for use in systems may help make ultra-hig
A team led by Kang-Kuen Ni (center), including Gabriel Patenotte (left) and Samuel Gebretsadkan, among others, successfully trapped molecules to perform quantum operations for the first time.
Trapping molecules for use in systems may help make ultra-high-speed experimental technology even faster
Molecules haven’t been used in quantum computing, even though they have the potential to make the ultra-high-speed experimental technology even faster. Their rich internal structures were seen as too complicated, too delicate, too unpredictable to manage, so smaller particles have been used.
But a team of Harvard scientists has succeeded for the first time in trapping molecules to perform quantum operations. This feat was accomplished by using ultra-cold polar molecules as qubits, or the fundamental units of information that power the technology. The findings, recently published in the journal Nature, open new realms of possibility for harnessing the complexity of molecular structures for future applications.
“As a field we have been trying to do this for 20 years,” said senior co-author Kang-Kuen Ni, Theodore William Richards Professor of Chemistry and professor of physics. “And we’ve finally been able to do it!”
Physicists and engineers have been working to develop quantum computing for several decades. The technology, which exploits aspects of quantum mechanics for computation, promises speeds exponentially faster than classical computers, which could enable game-changing advances in fields including medicine, science, and finance.
“Our work … is the last building block necessary to build a molecular quantum computer.”
Annie Park, study co-author, postdoctoral fellow
Dominating the world of quantum computing are experiments with trapped ions, neutral atoms, and superconducting circuits. In these systems, tiny individual particles can be reliably trapped to serve as qubits and form quantum logic gates. The Harvard team’s paper details the far more complicated process involved with using molecules to form an iSWAP gate, a key quantum circuit that creates entanglement — the very property that makes quantum computing so powerful.
The researchers started by trapping sodium-cesium (NaCs) molecules with optical tweezers in a stable and extremely cold environment. The electric dipole-dipole (or positive-negative) interactions between the molecules were then used to perform a quantum operation. By carefully controlling how the molecules rotated with respect to one another, the team managed to entangle two molecules, creating a quantum state known as a two-qubit Bell state with 94 percent accuracy.
Logic gates enable information processing in quantum computers just as they do in traditional computers. But while classical gates manipulate binary bits (0s and 1s), quantum gates operate on qubits — which can achieve what are called superpositions, existing in multiple states simultaneously. That means quantum computers can do things that would be impossible for traditional machines, such as creating entangled states in the first place — or even performing operations in multiple computational states at once.
Quantum gates are also reversible and capable of manipulating qubits with precision while preserving their quantum nature. The iSWAP gate used in this experiment swapped the states of two qubits and applied what is called a phase shift, an essential step in generating entanglement where the states of two qubits become correlated regardless of the distance in between.
“Our work marks a milestone in trapped molecule technology and is the last building block necessary to build a molecular quantum computer,” said co-author and postdoctoral fellow Annie Park. “The unique properties of molecules, such as their rich internal structure, offer many opportunities to advance these technologies.”
Scientists have dreamed since the 1990s of harnessing molecular systems, with their nuclear spins and nuclear magnetic resonance techniques, for quantum computing. A series of early experiments showed encouraging results, but molecules proved generally unstable for use in quantum operations due to their unpredictable movements. That can interfere with coherence, the delicate quantum state necessary for reliable operations.
But trapping molecules in ultra-cold environments, where the molecule’s intricate internal structures can be controlled, helps overcome this hurdle. Once holding these molecules with optical tweezers — with precisely focused lasers for controlling tiny objects — researchers were able to minimize the molecules’ motion and manipulate their quantum states.
Making this breakthrough possible were several members of Ni’s lab including Lewis R.B. Picard, Annie J. Park, Gabriel E. Patenotte, and Samuel Gebretsadkan, as well as physicists with the University of Colorado’s Center for Theory of Quantum Matter.
To evaluate the whole operation, the research team measured the resulting two-qubit Bell state and studied errors caused by any motion that did occur. This left them with ideas for improving the stability and accuracy of their setup in future experiments. Switching between interacting and non-interacting states also enabled researchers to digitize their experiment, providing additional insights.
“There’s a lot of room for innovations and new ideas about how to leverage the advantages of the molecular platform,” Ni said. “I’m excited to see what comes out of this.”
This research was supported by multiple sources including the Air Force of Scientific Research, the National Science Foundation, the Physics Frontier Center, and Multidisciplinary Research Program of the University Research Initiative.
Health
Now that we have new ‘miracle’ diet drugs, what’s the point of exercising?
Getty Images
Anna Lamb
Harvard Staff Writer
January 17, 2025
6 min read
Experts say weight loss isn’t at top of list of health, longevity gains that come from activities like walking, hitting gym
New diet drugs are making it easier to lose weight. So does that mean we can stop exercising? Health experts say
Now that we have new ‘miracle’ diet drugs, what’s the point of exercising?
Getty Images
Anna Lamb
Harvard Staff Writer
6 min read
Experts say weight loss isn’t at top of list of health, longevity gains that come from activities like walking, hitting gym
New diet drugs are making it easier to lose weight. So does that mean we can stop exercising? Health experts say no. There is a long list of upsides to going for a walk or hitting the gym, and weight loss isn’t necessarily at the top.
“Exercise is good for everything from cognition and mental health benefits such as preventing neurocognitive disorders like Alzheimer’s disease to cardiovascular benefits like preventing mortality from cardiovascular disease, maintaining vascular function, and improving lung strength and lung function,” said Christina Dieli-Conwright, an associate professor in the Department of Nutrition at the T.H. Chan School of Public Health.
“Exercising regularly can even benefit the gastrointestinal system, like gut motility, digestion and the gut microbiome. … Depression, anxiety, sleep, fatigue, pain — I can’t think of a body system that is not benefited by exercise,” she added.
But, while exercise can help in losing weight, it isn’t a magic bullet, she said.
“Historically speaking, the thought behind exercise and weight loss is a little bit erroneous. Exercise alone does not typically put an individual into enough of a caloric deficit to cause weight loss,” she said.
Why? For starters consider that exercise, on average, can burn from 200 to 700 calories an hour, while consuming that many calories can be done in minutes.
And most of us appear to be poor at keeping track of what we’re taking in vs. what we’re burning.
According to the Centers for Disease Control, more than 73 percent of Americans are overweight or obese. At the same time, almost half of all adults met activity guidelines for aerobic physical activity during the period of a year, and nearly a quarter met guidelines for both aerobic and muscle-strengthening activity.
7 to 15Hours of exercise a week significantly lowers cancer risk, according to 2019 study
Medical experts say both exercise and maintaining a healthy weight are important components of promoting overall health and longevity.
“Because the effects of weight loss on diabetes control and risk of diabetes is stronger than for exercise, but for other things like heart disease and living longer — they look like they’re about equivalent,” said I-Min Lee, a professor in the Department of Epidemiology at the Chan School and professor of medicine at Harvard Medical School.
In 2019, Lee helped author a study on physical activity and cancer risk that showed that seven to 15 hours of exercise a week can significantly lower one’s risk of seven types of cancer. That benefit decreases with an overweight BMI, but still shows an improved risk for six cancers: colon, breast, kidney, myeloma, liver, and non-Hodgkin lymphoma.
“Depression, anxiety, sleep, fatigue, pain — I can’t think of a body system that is not benefited by exercise.”
Christina Dieli-Conwright, T.H. Chan School of Public Health
Lee advises those who are looking to begin an exercise regimen to start small.
“That way you get a little bit of benefit,” she said, “and it’s also very encouraging, because if it’s an amount that’s doable, and you succeed, it might make you want to do more.”
And doing more is good for everyone, she said. A good strategy, according to Lee, is to try to add 10 minutes to your routine — whatever it may be. If you walk for 20 minutes a day, go for 30 until you meet or exceed the recommended 150 minutes of weekly exercise.
Edward Phillips, an assistant professor of physical medicine and rehabilitation at HMS, and founder and director of the Institute of Lifestyle Medicine at Spaulding Rehabilitation Hospital, agrees.
“If I ask someone how easily they think they could add a bottle of water in the morning or in the afternoon to combat dehydration, they’re going to say, ‘That’s not so hard.’ If they start doing that, and they also add in a five-minute walk after lunch, which is really healthy, and also easy to achieve, then when I check in with them three weeks later, they go, ‘I’m drinking more water. I feel better. And by the way, the five-minute walk turned into a 10-minute walk.’”
Phillips is also host of the WBUR podcast “Food, We Need to Talk,” covering health and fitness. He said when patients don’t see changes on the scale, they need tangible reasons to keep working out — and there are apparent reasons.
“People need a good story in order to make changes that would result in meaningful health changes,” he said. “Exercise allows you to be more functional. You can get out of a chair more easily. You can sit in the chair more easily. … Or when a friend says, ‘Let’s go downhill skiing this weekend,’ and you’re like, ‘I haven’t done that in years,’ you say. ‘I could try it, because I’ve been exercising.’”
Dieli-Conwright said it helps to do anything a couple of times a week that gets you out of breath.
“You’re going to get more bang for your buck if you do both aerobic and resistance exercise, though,” she said. “The reason is that aerobic exercise is going to tax the cardiorespiratory system more than resistance or weightlifting. That type of exercise is fantastic for muscle strength. But with both you are going to target glucose metabolism, which is going to be important for managing hyper- and hypoglycemia, diabetes management, things like that.”
She adds that it’s also important to interrupt sitting time or sedentary behaviors.
“Once an hour, get up for two to three minutes even, and just stand up and down and squat or take a two-minute little walk, and go up and down the stairs a couple of times. That can actually help to also manage glucose, which leads, again, back into diabetes risk,” she said.
But Dieli-Conwright emphasizes that creating an exercise habit is key.
“We all know that obesity is incredibly bad. It leads to so many different other co-morbid conditions, specifically heart disease and diabetes. However, there’s so much data that’s overlooked that supports the paradigm that I generally call, and others call, being fit and fat,” she said, essentially being overweight, yet metabolically healthy.
Work & Economy
Is small thinking the new American way?
Photo illustration by Judy Blomquist/Harvard Staff
Christy DeSmith
Harvard Staff Writer
January 16, 2025
8 min read
Study says tighter land-use controls have hurt productivity and innovation among builders, fueling housing crisis
U.S. productivity soared in the second half of the 20th century, creating benefits for consumers in
Photo illustration by Judy Blomquist/Harvard Staff
Christy DeSmith
Harvard Staff Writer
8 min read
Study says tighter land-use controls have hurt productivity and innovation among builders, fueling housing crisis
U.S. productivity soared in the second half of the 20th century, creating benefits for consumers in the form of lower prices across a wide range of goods. But one critical sector proved a glaring exception: housing.
Today the country faces a housing affordability crisis, with ownership out of reach for a growing set of Americans. The price of a new single-family home has more than doubled since 1960, due to a variety of commonly cited factors including labor and material costs. But a recent economics working paper highlights another reason for the rising cost of putting a roof over one’s head: the stifling impact of “not in my backyard,” or NIMBY, land-use policies on builders.
“If there’s one thing we’ve known since the time of Adam Smith, but even more so since the time of Henry Ford, it’s that mass production — repetition — makes things cheap,” said Edward Glaeser, a co-author of the research and the Fred and Eleanor Glimp Professor of Economics. “But land-use regulation stops us from building a mass-produced home and requires instead a very idiosyncratic home. It means every project will be micromanaged. Every project will be small. Every project will be a bespoke build to satisfy five different requirements from the community.”
The new research was inspired by a 2023 paper by University of Chicago economists Austan Goolsbee and Chad Syverson, who documented what they termed “the strange and awful path” of declining productivity in U.S. construction. The building sector, they found, had outpaced the rest of the U.S. economy throughout the 1950s and well into the ’60s. Then came a dramatic shift. Between 1970 and 2000, even as the overall economy continued to grow, productivity in the construction sector, measured in housing starts per worker, fell by 40 percent.
At one point during the post-WWII building boom, the biggest builders worked with land parcels averaging more than 5,000 acres, developing thousands of homes on each.
They had scale on their side: In housing construction, firms with 500 or more employees produce four times more units per employee than firms with fewer than 20 employees. Today, firms are much smaller than those of the past.
Innovation has fallen, too. Patenting levels for construction and manufacturing moved together for much of the 20th century. After 1970, patents per employee soared in manufacturing — but they declined in construction.
New homes now cost twice as much in real terms as they did in 1960, putting homeownership out of reach for a growing set of Americans.
The findings resonated with Leonardo D’Amico, a Ph.D. economics candidate in the Griffin Graduate School of Arts and Sciences who arrived at Harvard from Italy in 2019. “America is extremely productive in so many industries, especially compared to Europe,” he said. “But housing construction was this glaring example of missing productivity.”
Glaeser and D’Amico partnered with three co-authors, including William R. Kerr, the Dimitri V. D’Arbeloff – MBA Class of 1955 Professor of Business Administration at Harvard Business School, to investigate whether the rise of NIMBYism had driven the sector’s divergence. They started in the early 1900s, seeking a broad view of innovation and productivity among U.S. builders.
The century of Census data the team collected showed a steep increase in housing productivity from 1935 to 1970. In fact, the researchers saw that the number of homes produced per construction worker during this period often grew faster than total manufacturing output per industrial worker — including the number of cars produced by auto workers. “This goes against the idea that there is something about the housing sector that makes it impossible to grow,” D’Amico emphasized.
Like Goolsbee and Syverson, D’Amico and colleagues found that construction productivity hit reverse circa 1970 — just as the volume of local and regional land-use regulations picked up. In contrast, the authors saw that productivity in auto manufacturing continued to climb, with cars today costing 60 percent less (when adjusted for inflation) than in 1960.
As land-use regulations climbed, housing construction productivity sank compared with auto manufacturing
Source: “Why has construction productivity stagnated? The role of land-use regulation”
To explain the role of regulation in high housing costs and falling construction productivity, the new paper presents a model in which the proliferation of land-use regulations served to limit the size of construction projects. Smaller projects, in turn, led to smaller firms with fewer incentives to invest in cost-saving innovations associated with mass production. Testing the model meant quantifying the size of housing developments over time. Drawing on historical real estate data from CoreLogic and other sources, the researchers found that the share of single-family housing yielded by large-scale building projects has indeed been in decline.
“Documenting the size of projects over time is something we’re particularly proud of in terms of empirical contributions,” said Glaeser, an urban economist who has studied housing for more than 25 years. “It enabled us to show the decline or even elimination of really big projects over time.”
The paper includes a section comparing the scale of current projects against that of Long Island’s famous Levittown development, home to more than 17,000 cookie-cutter houses built in the late ’40s and early ’50s.
Edward Glaeser.
Niles Singer/Harvard Staff Photographer
Leonardo D’Amico.
“Entrepreneurs like William Levitt figured out ways to mass-produce housing on America’s suburban frontier,” Glaeser said. “They sent carpenters up and down the street; they sent plumbers up and down the street. It was all moving toward economies of scale, with Levitt moving into modular, prefabricated housing by the 1960s.”
Post-war builders developed thousands of single-family homes on land parcels that averaged more than 5,000 acres. Today, the researchers write, the share of housing built in large projects has fallen by more than one-third, while developments on more than 500 acres are “essentially nonexistent.”
The researchers also detail the productivity advantages enjoyed by large builders like Levitt. Using economic and business Census data, they show that construction firms with 500 or more employees produce four times as many housing units per employee than firms with fewer than 20 employees. Yet employment by large homebuilders started falling in 1973, with no comparable decline in manufacturing or the economy at large.
Firms proved smallest — and least productive — in areas most inclined toward NIMBYism, the researchers found. Homebuilders in these regions navigate rules covering everything from lot size and density to design as well as planning commissions, review boards, and sometimes even voter referendums. But a closer look at the construction sector’s patenting and R&D activity uncovered nationwide impacts.
Since the 1970s, construction patents have lagged other industries
Source: “Why has construction productivity stagnated? The role of land-use regulation”
“We see in the data that the construction industry was patenting and innovating as much as other industries before the 1970s,” said D’Amico, who is working with fellow Ph.D. candidate Victoria Angelova on a separate paper that investigates the connection between housing costs and fertility rates — underscoring how housing affordability can influence the most fundamental decision-making.
More than 150 years of patenting activity showed the construction industry lagging in the last three decades of the 20th century. “At first we thought maybe it’s because building suppliers were innovating; it’s just not the builders themselves,” D’Amico said. “But we looked at manufacturing firms that serve the construction industry and, remarkably, even their share of innovation has gone down compared to manufacturing firms overall.”
One upshot is what Glaeser characterized as “a massive intergenerational transfer” of housing wealth. He cited his 2017 paper with University of Pennsylvania finance and business economist Joseph Gyourko, who is also a co-author on the new paper. The pair showed that 35- to 44-year-olds in the 50th percentile of U.S. earners averaged nearly $56,000 of housing wealth in 1983, while the same demographic held just $6,000 by 2013. Compare that with median earners ages 65 to 74, who averaged more than $82,000 in 1983 and $100,000 in 2013.
$87,120
Average home equity for 45- to 54-year-olds at the 50th percentile of U.S. earners in 1983
$30,000
Average home equity for 45- to 54-year-olds at the 50th percentile of U.S. earners in 2013
Source: Survey of Consumer Finances
“For me, it harkens back to a model of economic growth and decline that was put forward by Mancur Olson in the 1980s,” said Glaeser, citing the economist/political scientist who described a historical pattern of stable societies generating powerful insiders who guard their own interests by effectively shutting out up-and-comers.
Glaeser was pursuing his Ph.D. at the University of Chicago in the early 1990s when he first encountered Olson’s “The Rise and Decline of Nations” (1982). At the time, the book’s ideas struck him as apt descriptions of the country’s coastal housing markets. But today, Glaeser said, the problem is more widespread.
“Olson captured the unfortunate reality that insiders — or people who have already bought homes — have figured out how to basically stop any new homes from being created anywhere near them,” Glaeser said.
Science & Tech
Wish you had a better memory?
Illustrations by Liz Zonarich/Harvard Staff
January 16, 2025
1 min read
Take our research-based quiz for tips on improving recall when it matters most
Have you ever struggled to remember somebody’s name at a party or crammed for an exam only to blank during the test? In their 2023 book “Why We Forget and How to Remember Better,” brain scientists Andrew Bu
Take our research-based quiz for tips on improving recall when it matters most
Have you ever struggled to remember somebody’s name at a party or crammed for an exam only to blank during the test? In their 2023 book “Why We Forget and How to Remember Better,” brain scientists Andrew Budson and Elizabeth Kensinger, both Harvard alums, explain how memory works and offer research-based tips on optimizing your ability to recall. They helped us develop the following quiz so readers can test how much they really know about memory.
Health
Death, destruction — and trauma — of L.A. wildfires
Malibu home destroyed in the Palisades wildfire outside Los Angeles.Brandon Bell/Getty Images
Alvin Powell
Harvard Staff Writer
January 15, 2025
8 min read
Psychiatric epidemiologist discusses mental health toll from displacement and loss, the path forward for victims
Lives have been lost and disrupted, and thousands of homes and
Death, destruction — and trauma — of L.A. wildfires
Malibu home destroyed in the Palisades wildfire outside Los Angeles.
Brandon Bell/Getty Images
Alvin Powell
Harvard Staff Writer
8 min read
Psychiatric epidemiologist discusses mental health toll from displacement and loss, the path forward for victims
Lives have been lost and disrupted, and thousands of homes and businesses have been destroyed as wind-whipped wildfires continue to burn around Los Angeles a week after they began. Mental health professionals expect emotional and psychological wounds will endure long after the blazes have been extinguished.
The Gazette spoke with Karestan Koenen, an expert in psychological trauma at the Harvard T.H. Chan School of Public Health, who investigated the mental health impacts of the 2018 Paradise fire, which destroyed the town of Paradise, California, killed 85, and became the deadliest and costliest fire in state history. Koenen, a professor of psychiatric epidemiology, talked about what to expect in the days and weeks ahead.
In the Los Angeles fires, we have at least two dozen dead, more than 100,000 have been evacuated, more than 12,000 structures burned. That’s a lot of loss and upheaval. Are you expecting mental health impacts right away or more likely later?
We would expect mental health concerns to manifest right away, but the first thing is that everyone needs to be safe. Their basic needs have to be addressed. People lost homes but also places of employment, schools, churches, community structures, support systems, and different aspects of life. There’s a lot of research that shows that one of the things that predicts poor mental health outcomes after disasters is the disruptions in things like employment, housing, etc. So, one of the best things to prevent long-term mental health consequences is to address people’s basic needs for a safe place to live, for food, for work.
How much variability do you see in such a situation? I imagine there’s a different impact if you just had to evacuate versus your home burning down or you know a neighbor who died.
There’s a lot of variation in experience. One of the reasons the Paradise fire was so traumatic was because people had little warning. It is particularly traumatic when your life is threatened, and they were evacuating while fire was burning around them.
I’ve done a lot of interviews on trauma over the years and the person I did the Paradise interviews with, Dr. Roger Pitman, an expert on PTSD, said the only interviews where he saw as much trauma were in war, in combat veterans and civilian war survivors. It’s because of all the losses. When people lose their homes, it’s the loss of the home itself, but they also lose their clothing, stuffed animals, family photos, heirlooms, boxes of their kids’ newborn stuff. And pets. Losing a pet can have a really big impact. Pets often run away when there’s a fire, and their owners experience guilt that they were not able to save them.
Family members sift through the remains of a relative’s home in Altadena, California.
Justin Sullivan/Getty Images
Is it different for firefighters versus people who are victims and being evacuated?
Yes. Firefighters and first responders are trained in how to deal with the situation. Being prepared, having rehearsed what to do will reduce the chance of having negative outcomes.
Firefighters and first responders can still experience trauma, especially if their lives are threatened, but they have a purpose. They’re doing something to help. One of the hardest things to handle in a disaster is the feeling of helplessness, that loss of control. If you’re evacuated, you don’t know where you’re going — maybe to temporary housing — and you don’t control when you can go back to your house. So, when we talk about trauma, we talk about losses and things that are out of your control, that are threatening and unpredictable. Fires are all of those things.
Are there some people who, under the same circumstances, are unaffected, and can we predict who that will be?
We can’t predict that very well, but there are things that make people more or less vulnerable. People with a history of mental disorders, depression, or physical health problems might be more vulnerable. People who don’t have good supports, don’t have stable employment, don’t have insurance, they would be more vulnerable, under more stress after the fires.
Then there’s the exposure itself, whether you saw your home burn or someone die versus being safely evacuated. Maybe bad things happened, but you didn’t witness them. There’s a lot of evidence that how kids feel will be influenced a lot by how their parents respond to what’s going on. Kids are vulnerable but can be buffered by their parents and other supports, like the school still being open, so they can still go even though they’ve been evacuated. That’s a better situation, because then they at least still have a normal school day.
So, if you’re a parent, you should try to kind of act as if things are under control, even if that’s not what you feel?
No, I’m not saying that. Rather, it’s an argument for parents to make sure they’re attending to the things they need, like when you’re on an airplane: Put on your own oxygen mask first, before you put on your kid’s oxygen mask. If parents can do things that help them feel better, it will trickle down. Supporting parents and caretakers is one of the best ways to support kids.
“There’s a lot of research that shows that one of the things that predicts poor mental health outcomes after disasters is the disruptions in things like employment, housing.”
Karestan Koenen
Is there an ideal time frame after we take care of basic needs that mental health assessments and care interventions should start?
After fires like this, a lot of people will show distress. That might look like being hypervigilant, on guard, being tense, feeling anxious, worrying, being reactive to things in the news about a fire, for example. They could be depressed, sad, have trouble sleeping, or trouble concentrating. It’d be normal to experience those things after what happened.
But many people heal on their own, even with pretty extreme trauma. A lot of people go through a natural recovery process, talking to friends, speaking with people in the community. In a few weeks to a month — after the fires are out and things are stable — people should be feeling better, their anxiety should be going down.
If it’s persisting or getting worse, that might be a time to get some help. Another thing to watch for is avoidance, isolating, or using substances to cope. Keep in mind too that the things you used to like to do, like exercising and going outside to enjoy nature — activities interrupted by the fires — there’s evidence that they help people’s mental health. So as soon as possible, take some time to do things you enjoyed.
How do you know when it’s time to seek professional help?
When the things I mentioned — anxiety, feeling sad most of the time, problems sleeping, problems concentrating — start interfering with things like work: You are back, but you can’t get your work done; you can’t concentrate. Also, if they’re interfering with relationships: You find yourself avoiding people you normally like spending time with or you’re losing your temper a lot more, in an extreme way. If you’re feeling bad, it’s not getting better, and it’s interfering with your life, that’s definitely time to get help.
Is there anything you learned from the Paradise experience that might be helpful in the aftermath of the fires in L.A.?
We already talked about the importance of attending to people’s basic needs — a safe place to live, food, etc. But there’s also the importance of rebuilding the community. In Paradise, the loss of a community as well as individual homes was what made it even worse for people because they lost their way of connecting with people. So, if there are ways to connect people, provide places to gather and connect, that’s important. We often focus on the basic needs, like food, shelter, clothing — which totally makes sense — but we also need to focus on the community connection.
So, if you belong to a church that burned down, maybe get people together somehow?
It should probably be others, leaders or relief organizations, who facilitate that. If people are overwhelmed, dealing with their own basic needs, they’re not going to have a lot of extra energy to organize things.
One thing with the L.A. fire is it seemed to affect people with different socioeconomic statuses, including superstars. My hope is that those with more resources will be able to help those with fewer. Negative mental health consequences of disasters, like the L.A. fires, are common but they can be mitigated and even prevented if the right supports are in place and the community comes together.
Where to get help
Koenen suggests the following resources for those affected by the wildfires:
Health
Aha moment in psych class clarifies childhood mystery
Niles Singer/Harvard Staff Photographer
Samantha Laine Perfas
Harvard Staff Writer
January 15, 2025
6 min read
Inspires Susan Kuo’s research probing role of genetics in schizophrenia, autism
A series focused on the personal side of Harvard research and teaching.
When Susan Kuo was growi
Aha moment in psych class clarifies childhood mystery
Niles Singer/Harvard Staff Photographer
Samantha Laine Perfas
Harvard Staff Writer
6 min read
Inspires Susan Kuo’s research probing role of genetics in schizophrenia, autism
A series focused on the personal side of Harvard research and teaching.
When Susan Kuo was growing up, a relative came to live with her and her immediate family in Vancouver, Canada. Previously warm and affectionate, the family member had become suspicious and withdrawn and struggled to communicate needs.
What Kuo didn’t know at the time, but realized later while taking psychology classes as an undergraduate at the University of British Columbia, was that some of the behaviors exhibited by her family member were signs of schizophrenia. Being able to label what she witnessed brought clarity to a confusing time in her life. Kuo resolved to bring that same clarity to others about neuropsychiatric disabilities — and how they can vary across people’s lifetimes.
“If we had been able to figure out more specific services earlier, that would’ve been really helpful in terms of getting my family member back on track,” said Kuo, now a postdoctoral researcher at the Center for Genomic Medicine and Department of Psychiatry at Mass General studying autism and schizophrenia. She is also affiliated with the Stanley Center for Psychiatric Research at Broad Institute.
Kuo had always been drawn to medicine, and once exposed to psychology it cemented her professional path. While earning her Ph.D. in clinical psychology at the University of Pittsburgh, she zeroed in on schizophrenia.
Uncovering developmental patterns
Kuo wanted to better understand genetic effects contributing to schizophrenia that may be associated with changes in brain and behavior throughout people’s lifetimes. Her relative, for example, showed signs of schizophrenia upon reaching young adulthood, which is in line with the typical onset age of 18 to 25 years.
She wondered whether there were notable patterns among relatives, compared to people without a family history of schizophrenia, that suggest genetic effects.
“First-degree relatives, siblings and such, share on average 50 percent of their genes in common” with a person with schizophrenia, explained Kuo’s Ph.D. adviser Michael Pogue-Geile, whose lab studies family genetics to pinpoint potential factors that might contribute to the onset of schizophrenia.
Working closely with Pogue-Geile, Kuo conducted a study that divided biological relatives of people with schizophrenia into three age groups: pre-20s, 20s, and post-20s. Kuo and Pogue-Geile discovered subtle differences in cognitive function and brain structure among relatives in their 20s who did not have schizophrenia diagnoses but carried more schizophrenia-associated genetic variants than the general population.
The findings suggest some genetic effects that may contribute to the onset of schizophrenia are more salient around this time of life. Pogue-Geile offered some possible explanations for why that may be: Some genes turn on and off during different times in a person’s lifespan (think puberty); also, people often experience significant change and stress as they enter adulthood.
“That was very innovative research that not really any other people had done in the field,” Pogue-Geile said.
Predicting intervention responses
Kuo continued working with people with schizophrenia during her clinical internship at UCLA Medical Center. Keith Nuechterlein, whose lab at UCLA is also a clinic for people experiencing their first episode of schizophrenia, said that Kuo’s “superb research skills” and talent for psychotherapy contributed significantly to the lab. The team published a paper that suggested childhood and teenage experiences before a first episode of schizophrenia predict how well certain interventions would work.
“If we can intervene successfully at the beginning of this illness, the hope is that we can change the trajectory.”
Keith Nuechterlein, director, UCLA Semel Institute of Neuroscience and Human Behavior
While on average many young people adapt well to various roles and responsibilities before their first episode of schizophrenia, Kuo noticed that the average was hiding a wide range of experiences. People with schizophrenia generally follow one of three developmental trajectories from childhood through adolescence: Some maintain social ties and keep up schoolwork; others progressively show challenges leading up to the onset of their first episode of schizophrenia; and others struggle with social ties and schoolwork starting in childhood. Kuo’s work suggests those who fall in the last group showed the highest levels of improvement with cognitive training interventions.
“That’s actually encouraging; it helps us know how to target that kind of cognitive training,” Nuechterlein said. “If we can intervene successfully at the beginning of this illness, the hope is that we can change the trajectory.”
Planning clinical and educational resources
For Kuo, she’s noticed that genetics research to date has rarely captured how phenotypes, particularly those that impact quality of life, may shift over time for people with neuropsychiatric disabilities. She hopes to change that.
Now at the Mass General, where her research focuses on autism as well as schizophrenia, Kuo has another opportunity to study relationships between genetic variation and phenotypic variation throughout development.
Elise Robinson, an epidemiologist and geneticist who supervises Kuo’s research, discussed Kuo’s contribution to the lab.
“Heterogeneity in autism is massively underdiscussed, which has implications for clinical practice and family experience,” said Robinson, whose lab is based at Mass General Hospital’s Center for Genomic Medicine and Department of Psychiatry and at Broad Institute’s Stanley Center for Psychiatric Research.
“By understanding the genetic and phenotypic diversity, the hope is that we can better match different services to folks who could use them,” Kuo said. “What are the supports they could use down the line as you’re anticipating some of the challenges — or some of the strengths — they might develop?”
Since joining the Robinson lab, Kuo has been studying this variability among people with neuropsychiatric disabilities at scale, with an eye toward building clinical and educational resources. The team analyzed patterns of attaining early developmental milestones, such as walking and talking, in over 17,000 autistic children compared to over 4,000 siblings without an autism diagnosis. They found that while some autistic children reached these milestones on time, autistic children on average reached milestones up to 20 months later. Later milestones like speaking phrases had longer delays than earlier milestones like smiling.
Building on these findings, Kuo’s team is currently working on a suite of online, public resources designed for clinicians and families of autistic children to learn about the latest genetics research and navigate considerations surrounding clinical genetic testing.
As for Robinson, she continues to be impressed by Kuo’s drive.
“She’s incredibly diligent; she’s also invariably thoughtful and nonjudgmental and wonderful about mentoring people in our team,” Robinson said. “It’s a large part of why she’s such a natural leader, an obvious budding leader in our community.”
Campus & Community
Alumni donations drive progress in Economics Department
The site of the Economics Department’s future home, Pritzker Hall.Photo by Grace DuVal
January 15, 2025
5 min read
Gifts support professorships, spaces in future Pritzker Hall
Alumni from classes spanning 40 years have stepped forward to support Harvard’s vision for a new era of economics education and research. Gifts from
Alumni donations drive progress in Economics Department
The site of the Economics Department’s future home, Pritzker Hall.
Photo by Grace DuVal
5 min read
Gifts support professorships, spaces in future Pritzker Hall
Alumni from classes spanning 40 years have stepped forward to support Harvard’s vision for a new era of economics education and research. Gifts from Joseph T. Tsai ’98; Jeffrey T. Tsai ’01, S.M. ’04; Jason T. Tsai ’05; Alexander Slusky ’89, M.B.A. ’92, and Danna Slusky; and Don Smith ’66 will bolster the department’s future home, Pritzker Hall, and establish two new professorships.
“The collective generosity of these alumni is powering a transformative vision for the future of economics research at Harvard, shaping the next generation of scholars and policymakers,” said Hopi Hoekstra, Edgerley Family Dean of the Faculty of Arts and Sciences. “We are deeply grateful for their support, which is advancing the creation of an innovative new building and endowed professorships, firmly establishing the critical intellectual role Harvard’s economics program will play in developing the future of the field.”
For more than 100 years, the Economics Department in the Faculty of Arts and Sciences has produced scholarship and policy ideas aimed at the world’s most pressing problems, including recessions, gender and racial inequality, climate change, and global poverty. Revered for its top undergraduate and graduate programs, the department educates more than 500 undergraduate concentrators and nearly 200 graduate students every year. Economics faculty have earned countless accolades including multiple MacArthur Awards, Clark Medals, and Nobel Prizes, including the Nobel awarded in 2023 to Claudia Goldin, Lee and Ezpeleta Professor of Arts and Sciences and Henry Lee Professor of Economics.
New spaces for new kinds of work
The new support will help to build the future home for the Economics Department, which began with an impactful gift from Penny Pritzker ’81 and Bryan Traubert. Pritzker Hall will bring research and teaching together under one roof, in a space designed for interaction and collaboration.
“Our hope is that the new building will be a machine for interactions that will connect students and faculty and generate ideas that change the world,” says Ed Glaeser, Fred and Eleanor Glimp Professor of Economics. “Pritzker Hall has been designed to pull in hopeful undergraduates — to make economics as exciting and inclusive as possible — to educate them to lead and do cutting-edge research that will inform policymaking everywhere. The spaces are both beautiful and functional, designed so that knowledge will flow freely and that the ‘aha’ moments that have happened in the Harvard Economics Department will continue for decades.”
The three Tsai brothers made their gift to name the event and teaching space in honor of their father, Hong-Tu Tsai, chairman of Cathay Financial Holdings. The Tsai Family Event Area and Terrace will be a high-profile venue for convening faculty, visiting scholars, community members, and civic and world leaders for scholarly and public audiences.
“We wanted to be part of Harvard’s new vision for economics,” said Joe Tsai. Members of the Tsai family have been avid supporters of Harvard College for decades, including through a notable gift to the Center for Government and International Studies in 1996 and the named Tsai Auditorium. “We were inspired by the approach being taken to the development of Pritzker Hall, which will draw scholars together in a highly interactive space and nourish the intellectual immersion at the foundation of the Harvard undergraduate experience. Our father helped make Harvard possible for us, and we’d like to help others have the same transformational opportunities that we did.”
Investing in talent and fresh perspectives
Two separate gifts, one from the Slusky family and another from Smith, will support new professorships in important fields of study, ensuring the department can meet the needs of a rapidly evolving research landscape. The Slusky Family Professorship of Economics and Markets Fund will be awarded to an eminent scholar of economics who studies real-world applications.
“Economics faculty gave me a great foundation of knowledge that I’ve benefited from ever since,” says Alexander Slusky, reflecting on his opportunity to attend Harvard six years after emigrating from the former Soviet Union. He established the professorship in part due to the mentoring he received as an undergraduate by department luminaries including N. Gregory Mankiw, Martin Feldstein, and Richard Caves.
“The Harvard Economics Department is a critical part of educating future leaders of America,” said Slusky, who is founding partner of Vector Capital. “I want to help it grow this community.”
Smith also feels deep gratitude for his ties to the department and the mentoring he received from faculty member John Kenneth Galbraith. Smith has been passionate about environmental economics ever since his days as a Harvard student and as a longtime entrepreneur focused on developing clean energy. His gift will establish the Donald M. Smith Professorship Fund, to be awarded to a pioneering scholar who works in climate change, natural resources, or energy economics.
“I wanted to help Harvard find the best scholar in environmental economics,” said Smith, CEO and chief technology officer for EnviroBeef, a company dedicated to providing environmentally friendly beef. “It’s so wonderful for me very late in my professional life to be doing something that’s meaningful to Harvard.”
Campus & Community
Alumni committee announces Harvard board candidates
Photo by Grace DuVal
January 15, 2025
6 min read
Voting for Overseers and HAA elected directors starts April 1
The Harvard Alumni Association nominating committee has announced its candidates for the spring 2025 elections of the Harvard Board of Overseers and elected directors of the Harvard Alumni Association.
The nominating
The nominating committee brings together 13 alumni with varied backgrounds and includes three current or recent Overseers who have direct experience with the workings and needs of the board. The committee invites and receives suggestions about possible candidates from across the alumni community and reviews information on hundreds of prospective candidates as part of extensive deliberations throughout the fall term.
“The process of considering this year’s candidates for Overseer and HAA elected director has again revealed the extraordinary depth and diversity of talents and accomplishments across our alumni community,” said Robert N. Shapiro ’72, J.D. ’78, chair of the nominating committee, former Overseer, and past president of both the Harvard Alumni Association and the Harvard Law School Association. “These candidates exemplify a wide range of backgrounds and perspectives that will benefit the university. They share a devotion to Harvard as a beacon of academic excellence and a belief in its boundless potential to serve the wider world.”
The committee seeks to develop a set of Overseer candidates that takes account of the board’s present composition and the University’s future needs. The committee considers experience and accomplishment in an academic or professional domain important to the University; interest in and concern for higher education and for Harvard University as a whole; commitment to the overall quality and continual improvement of Harvard’s programs of education and research; willingness to invest the time and energy necessary for effective service; understanding of complex organizations, and leadership and consensus-building skills.
“I’m grateful to my committee colleagues for their thoughtfulness and insights in identifying this outstanding group of candidates,” Shapiro said. “And all of us are grateful to the candidates themselves for their willingness to invest their time and care in the Harvard community and its reach far beyond campus.”
Overseer candidates
Lanhee J. Chen ’99, magna cum laude, A.M. ’04, J.D. ’07, cum laude, Ph.D. ’09
David and Diane Steffy Fellow in American Public Policy Studies, Hoover Institution, and Director of Domestic Policy Studies, Public Policy Program, Stanford University; Partner, Brunswick Group Mountain View, California
Mark A. Edwards ’82, cum laude
Co-founder and CEO, Upstream USA; founder and former executive director, Opportunity Nation Brookline, Massachusetts
Mary Louise Kelly ’93, magna cum laude
M.Phil. ’95, University of Cambridge; journalist and broadcaster, co-host of “All Things Considered,” NPR Washington, D.C.
Nathaniel Owen Keohane, Ph.D. ’01
B.A. ’93, Yale University; president, Center for Climate and Energy Solutions New York, New York
Valerie Montgomery Rice, M.D. ’87
B.S. ’83, Georgia Institute of Technology; president and CEO, Morehouse School of Medicine Atlanta, Georgia
Michael Rosenblatt, M.D. ’73, magna cum laude
B.A. ’69, summa cum laude, Columbia University; advisory partner, Ascenta Capital; senior adviser, Bain Capital Life Sciences and Flagship Pioneering; former executive vice president and chief medical officer, Merck & Co.; former dean, Tufts University School of Medicine Newton, Massachusetts
Anjali Sud, M.B.A. ’11
B.S. ’05, University of Pennsylvania; CEO, Tubi; former CEO, Vimeo New York, New York
Courtney B. Vance ’82
M.F.A. ’86, Yale University; actor, producer, writer; president and chair, SAG-AFTRA Foundation La Cañada Flintridge, California
HAA elected director candidates
Daniel H. Ahn ’90, magna cum laude, M.B.A. ’97
Managing partner, Clearvision Ventures
Burlingame, California
Allison Lee Pillinger Choi ’06
Author
Bedford, New York
Theresa J. Chung ’98, magna cum laude, J.D. ’02
Administrative judge, U.S. Merit Systems Protection Board
Dallas, Texas
Colin J. Kegler ’97
Senior software engineer, HealthEdge Inc.
Provincetown, Massachusetts
Victoria “Vicky” Wai Ka Leung ’91, cum laude
M.B.A. ’98, New York University; managing director and consultant, EC M&A London, England
Nicholas J. Melvoin ’08
M.A. ’10, Loyola Marymount University; J.D. ’14, New York University; elected board member, Los Angeles Unified School District
Los Angeles, California
Pavlos P. Photiades ’88, magna cum laude
CEO, Photos Photiades Group
Nicosia, Cyprus
Angela M. Ruggiero ’02, cum laude, M.B.A. ’14
M.Ed. ’10, University of Minnesota; co-founder and chair, Sports Innovation Lab
Weston, Massachusetts
Sanjay Seth, M.P.A. ’19, M.U.P. ’19
B.A. ’12, Goldsmiths, University of London; former chief of staff and senior adviser for climate and equity, U.S. EPA New England
East Boston, Massachusetts
Candidates for Overseer may also be nominated by petition, by obtaining a required number of signatures from eligible voters. The deadline to submit petitions for the 2025 Overseers election is Jan. 30. Find more information on the nomination and election process here.
The election begins April 1. Completed ballots will be accepted until 5 p.m. on May 14. Harvard degree holders can vote online or by paper ballot for five anticipated vacancies on the Board of Overseers and for six openings among the HAA elected directors.
All Harvard degree holders as of Jan. 1, except for officers of instruction and government at Harvard and members of the Harvard Corporation, are eligible to vote for Overseer candidates. All Harvard degree holders as of Jan. 1 may vote for HAA elected directors.
The Board of Overseers is one of Harvard’s two governing boards, along with the President and Fellows, also known as the Corporation. Formally established in 1642, the board plays an integral role in the governance of the University, complementing the Corporation’s work as Harvard’s principal fiduciary board. As a central part of its work, the Board of Overseers directs the visitation process, the primary means for periodic external assessment of Harvard’s Schools and departments. Through its array of standing committees, and the roughly 50 visiting committees that report to them, the board probes the quality of Harvard’s programs and assures that the University remains true to its charter as a place of learning. More generally, drawing on its members’ diverse experience and expertise, the board provides counsel to the University’s leadership on priorities, plans, and strategic initiatives. The board also has the power of consent to certain actions, such as the election of Corporation members. The current membership of the board is listed here.
The HAA board, including its elected directors, is an advisory board that aims to foster a sense of community, engagement, and University citizenship among Harvard alumni around the world. The work focuses on developing volunteer leadership and increasing and deepening alumni engagement through an array of programs that support alumni communities worldwide. In recent years, the board’s priorities have included strengthening outreach to recent graduates and graduate school alumni and continuing to build and promote inclusive communities.
U.S. Supreme Court.Graeme Sloan/Sipa via AP Images
Nation & World
Is TikTok’s time nearly up?
Privacy and cybersecurity law expert examines national security, First Amendment issues as popular video website faces legal deadline
Christina Pazzanese
Harvard Staff Writer
January 14, 2025
6 min read
The clock appears to be winding down on TikTok’s future in the U.S. Beijing-based ByteDanc
Privacy and cybersecurity law expert examines national security, First Amendment issues as popular video website faces legal deadline
Christina Pazzanese
Harvard Staff Writer
6 min read
The clock appears to be winding down on TikTok’s future in the U.S. Beijing-based ByteDance, the firm behind the popular video-sharing website in the U.S., has until Sunday to sell TikTok to a non-Chinese owner or close.
In a law passed last year, Congress cited national security concerns in barring internet service providers and firms from hosting or offering apps controlled by foreign governments hostile to the U.S. Lawmakers say China could manipulate personalized video feeds to influence U.S. public opinion, and they note the website also gathers massive amounts of user data in the process.
ByteDance claims the law infringes on its First Amendment rights as well as those of users.
On Friday, the U.S. Supreme Court heard oral arguments in the case, TikTok v. Garland, and is expected to rule soon.
The Gazette spoke with Timothy Edgar, J.D. ’97, a privacy and cybersecurity law expert who teaches at Harvard Law School and Brown University. Edgar’s position is that the law limits the First Amendment rights of ByteDance and TikTok users in the U.S. This interview has been edited for clarity and length.
What question is the Supreme Court considering?
The court is being asked to consider whether the Protecting Americans from Foreign Adversary Controlled Applications Act is constitutional, whether it infringes on either the First Amendment rights of TikTok in TikTok v. Garland or the American video creators who use the platform in Firebaugh v. Garland.
The first question they’re going to have to decide is if TikTok has any First Amendment rights here. And then, if it does, does the government have a compelling interest that is narrowly tailored to its concerns, which is the test under the First Amendment for restrictions on speech.
My own view is that they do have First Amendment rights. Perhaps much more importantly, the 170 million Americans who are users of the platform and over 1 million creators obviously have First Amendment rights, so even if TikTok itself loses on that issue, the Supreme Court will still have to decide the First Amendment issue.
The second step is: Does the government’s argument satisfy the standard of strict scrutiny, which is the very demanding standard that the Supreme Court has set out for restrictions on free speech. In my opinion, it doesn’t.
“The main reason I side with TikTok in this case is that even if the risks are real, there are better alternatives than shutting down a whole platform.”
Timothy Edgar, privacy and cybersecurity law expert
Proponents of the law say it doesn’t ban TikTok or put national security above free speech. Can you talk more about the government’s position?
They’re disputing that it’s a ban by saying, “No, this is just an ownership regulation.” And in the area of broadcast regulations around TV stations, radio stations, and so forth, there’s precedent for restrictions or limits on foreign ownership of those media platforms.
The argument against that is that those cases have to do with a different era in media, dealing with the government having to make choices about which companies get the rare privilege of having a broadcast license, which is inherently limited because of spectrum scarcity.
The internet is not like that. There is no limit on how many websites or platforms can exist. It’s up to the public to decide whether to go to a website or not. And so the case is much closer to magazines or books, where the standard is very protective: The American people have the right to read whatever magazines or books they want. If the U.S. government thinks they’re foreign propaganda, as they did during the Cold War, that didn’t affect the rights of the companies to publish or the public to read them.
Foreign ownership restrictions might work in the context of broadcast licenses, but they shouldn’t work in the context of the internet for the same reason that they shouldn’t work in the context of publishing.
The second claim is: “It’s just an ownership restriction; it’s not a restriction on speech.” In the real world it is a restriction on speech because divestiture is not legally or practically or financially possible for TikTok because the Chinese government restricts the ability of foreign companies to acquire sensitive technology.
Chinese leaders believe the TikTok recommendation engine is valuable intellectual property that they will not permit to be exported. That means TikTok cannot find another owner and so, its only choice is to shut down.
What were some of the stronger arguments the U.S. government made?
The U.S. government does have some important arguments on its side. Maybe you can distinguish those broadcast-era cases, but they’re still there. Ultimately, the law is an ownership restriction rather than a ban, and there’s some history of ownership regulations being upheld by the Supreme Court.
I think they have strong national security arguments about the risk of U.S. user data being obtained by Chinese intelligence and about the risk of the Chinese government pressuring this social media platform to change its algorithm in order to serve Chinese government propaganda goals.
Those are both strong arguments. It’s reasonable for the Supreme Court to defer to the executive and the legislative branch on whether that’s a real risk.
The main reason I side with TikTok in this case is that even if the risks are real, there are better alternatives than shutting down a whole platform. I think it’s a terrible message for the U.S. to be sending to the rest of the world, to erect a great firewall when it comes to one of the world’s leading social media platforms. And it’s a very bad message for internet freedom and for our role in standing for internet freedom.
During oral arguments, the justices did not sound very receptive to TikTok’s argument. How likely is TikTok to prevail?
If I’m a betting man, I’m going to bet on the government winning this case. But that said, it’s always a mistake to listen to the arguments and the questions and assume that’s how it’s coming out. All the questions I heard were perfectly legitimate questions I might have asked counsel if I were trying to probe the weaknesses in a position I was considering adopting. The Supreme Court could end up surprising us and at least enjoining this law to have it go through a more regular process of judicial review.
Courtesy of Jon Hamm via Hasty Pudding Theatricals
Campus & Community
Jon Hamm named Man of the Year
Hasty Pudding to honor award-winning actor on Jan. 31
January 14, 2025
4 min read
Actor Jon Hamm is the recipient of the 2025 Man of the Year award, The Hasty Pudding Theatricals announced Tuesday.
The Hasty Pudding Theatricals, the oldest theatrical organization in the U.S., annually presents the
The Hasty Pudding Theatricals, the oldest theatrical organization in the U.S., annually presents the Man and Woman of the Year Awards to performers who have made lasting and impressive contributions to the world of entertainment. The Man of the Year award was established in 1967, with past recipients including Clint Eastwood, Tom Hanks, Robert De Niro, Harrison Ford, Samuel L. Jackson, Ryan Reynolds, and last year’s recipient Barry Keoghan, the 57th Man of the Year.
The Man of the Year festivities will take place on Jan. 31, when The Hasty Pudding Theatricals hosts a celebratory roast for Hamm at 6 p.m. and presents him with his Pudding Pot at Farkas Hall, the Pudding’s historic home in the heart of Harvard Square since 1888. A press conference will follow the roast at 6:20 p.m. Afterward, Hamm will attend a preview of the Hasty Pudding Theatricals’ 176th production “101 Damnations.”
“Let’s hope our roast doesn’t give him any heart palpitations — he’s had enough drama with that,” said Producer Willow Woodward. “But with his work ethic, we’re confident he’ll take on our stage with as much grit as Texas oil fields. He’s the perfect man to strike gold and earn his Pudding Pot this January.”
“We are beyond excited to honor Jon Hamm as our 2025 Man of the Year,” said President Cathy Stanton. “Of course, to claim his Pudding Pot, he’ll have to prove he’s the real Jon Hamm — we’ve seen how good he is at keeping an identity under wraps!”
Hamm’s nuanced portrayal of the high-powered advertising executive Don Draper on AMC’s award-winning drama series “Mad Men” firmly established him as one of Hollywood’s most talented and versatile actors. He earned numerous accolades for his performance, including an Emmy Award in 2015 for Outstanding Actor in a Drama Series, Golden Globe Awards in 2016, Television Critics Association Awards in 2011 and 2015, a Critic’s Choice Television Award in 2011, as well as multiple Screen Actors Guild nominations.
Currently, Hamm can be seen in the Paramount drama series “Landman.” Hamm appears opposite Billy Bob Thornton and Demi Moore in the modern-day tale of fortune seeking in the world of West Texas oil rigs. The series broke records when it debuted as the most-watched original show in Paramount+ history during its first four weeks.
Next, Hamm will star in the upcoming Apple TV+ series, “Your Friends and Neighbors.” The series will premiere on Apple TV+ in April. Additionally, Hamm will lead the live-action television series adaptation of the psychological thriller podcast “American Hostage,” in which he also starred. Hamm will reprise his role from the audio series that tells the true story of a radio reporter who is thrust into a life-or-death situation when a hostage taker demands to be interviewed on his show. Hamm starred in the fifth season of FX’s critically acclaimed anthology series “Fargo,” which premiered in November 2023. Hamm received an Emmy, Golden Globe, and Screen Actors Guild Award nomination for his outstanding performance as the villainous Sheriff Roy Tillman and the show received a 2024 Critic’s Choice Award nomination in the category of Best Limited Series. Hamm could also be seen in season three of Apple TV+’s “The Morning Show,” where he received an Emmy nomination as Outstanding Supporting Actor in a Drama Series.
A native of St. Louis, Missouri, Hamm received his bachelor of arts in English at the University of Missouri-Columbia and currently resides in Los Angeles.
Stephanie Mitchell/Harvard Staff Photographer
Health
Should we be panicked about bird flu? William Hanage says not yet.
But he warns that there is real cause for concern, CDC should take much closer look
Alvin Powell
Harvard Staff Writer
January 14, 2025
8 min read
The nation’s first human death due to the bird flu occurred this month, the latest development in a global outbreak that, whi
Should we be panicked about bird flu? William Hanage says not yet.
But he warns that there is real cause for concern, CDC should take much closer look
Alvin Powell
Harvard Staff Writer
8 min read
The nation’s first human death due to the bird flu occurred this month, the latest development in a global outbreak that, while mostly limited to birds and mammals such as minks, polar bears, cows, and domestic cats — has also sickened 67 Americans and has public health officials watching closely for signs that a human pandemic is in the offing.
There’s been more news of bird flu lately, including mounting poultry outbreaks and the first report of the death of a person in the U.S. The CDC’s assessment is that risk remains low. What’s your take? Is it time for the public to sit up and take notice?
I think it’s past time, but the recent death in Louisiana is not, in and of itself, reason to be more concerned. Bird flu deaths are rare events, but sooner or later we would expect one to occur.
It happened to a person who was relatively elderly and is reported to have had other underlying conditions, which is not to dismiss it in any way. They contracted it from birds in their backyard — I believe they kept chickens who likely were infected by wild birds.
Although this shows that we should be concerned about bird flu, it does not mean that there is necessarily a greater risk of it starting to transmit among humans, which would be really worrying.
“We will certainly see another flu pandemic. That’s not an ‘if’; it’s a ‘when.’”
One common characteristic in the outbreak in California dairy workers and the death in Louisiana seems to be “close contact.” Why is that important?
These viruses are not particularly good at infecting humans. It’s thought that’s because they don’t stick to the receptors in the upper part of the respiratory tract. Instead, they stick to receptors buried in the lower lung or in other tissues, like the conjunctiva in the eye.
That is one of the reasons we think we have been seeing conjunctivitis as a feature of infections in dairy workers. It’s easy to see how somebody exposed to infected milk — there’s a huge amount of virus in that milk — could splash a droplet into their eye or inadvertently touch their face, and the virus could gain access to them that way.
But for enough virus to get into the lower lung where these receptors are takes quite a lot of close contact.
California has recalled some raw milk products in which the virus has been detected. Does the pasteurization process kill the virus?
The pasteurization process renders the virus unviable. It can be detected in rare cases with very sensitive methods. But there’s a big difference between that and it being able to infect someone.
How concerning are reports that there may be many asymptomatic or mild cases among humans?
Mild cases, if they lead to transmission, are really important. Even if severe outcomes are rare, if a lot of people get infected then the severe cases will pile up.
The big question is whether infected farmworkers have transmitted to other people. If so, it hasn’t happened a lot because we would have detected more symptomatic cases. But blood tests could show if contacts of known cases show signs of having been exposed to the virus.
Hasn’t the CDC looked at that?
The CDC has done studies of farmworkers for evidence of having been exposed, but not of their contacts. That’s crucial.
“A key thing that we’ve not seen in the case of H5N1 and cattle are superspreading events.”
What worries you most?
We will certainly see another flu pandemic. That’s not an “if”; it’s a “when.” We cannot say how severe it will be, but we can say that it has the potential to be bad. We don’t talk enough about how we would detect it early and what we would do when it happens.
It won’t necessarily come from H5N1 in cattle. Most people I know think that probability is pretty low. But they also think that the probability is increased with more exposures among humans and opportunities for the virus to adapt to mammalian cells.
One serious potential concern is H5N1 outbreaks in swine, because if a pig gets infected with two different flu viruses, what comes out can be a mixture of the two, capable of transmitting among humans.
Are we doing enough with bird flu right now?
No. I would like to see more thorough investigation of the potential for transmission. I would like to see more careful surveillance of the adapting virus. I would like to understand more about the nature of the infections in the people we’ve identified them in.
The infection of the person who passed in Louisiana was reported to have mutations that indicated it was adapting to humans. Those mutations were not present in the birds from which the infection was obtained, suggesting the virus adapted in that person.
If the infection was relatively long-term, it recalls variants of COVID that almost certainly result from long-term infections in cases among people with difficulty mounting an effective immune response. Long-term infections with bird flu might be capable of doing something similar.
When they say, as in the Louisiana case, that there are “concerning” variations better adapted to infect humans, are they talking about respiratory spread?
They’re not talking about transmission. They’re talking about an adaptation to replicate effectively in human cells once the infection has started.
One of the tensions in the evolution of infectious diseases is that adapting to survive well inside you is not the same as adapting well to transmit to another person. Often there’s a tradeoff.
If you have enough cases, though, the chances of a mutation that eases transmission don’t need to be very high for the virus to spread. The difference between H5N1 and COVID is that there were literally millions of infections in COVID, while there have been very few human infections with H5N1.
That’s an important point. It takes a lot of tries for a mutation to hit on something that makes it dangerous, from a pandemic standpoint, but that’s not what we’re seeing.
Agreed. But what we are seeing is a generalist virus, and that’s a concern. Generalists that are capable of causing short transmission chains in a new species — like cattle or humans — have the opportunity to adapt to infect that species more effectively. That’s what we think happened at the very early stage of COVID. It probably caused a number of short transmission chains — superspreading events — and gained the ability to transmit effectively.
A key thing that we’ve not seen in the case of H5N1 and cattle are superspreading events. The transmission events to humans have been rare and required close contact. A superspreading event can, even if rare, lead to a lot of descending transmission chains, which take a while to burn out and provide opportunities for adaptation. Most introductions go extinct. But the ones that don’t eventually make up for it.
You mentioned there will be another flu pandemic. Have any of the previous pandemics been H5N1?
None, but what is concerning is that when virologists look at H5N1 and at the disease it causes in people unlucky enough to get sick, it awakens unpleasant thoughts of H1N1 in 1918-1919.
You said the public should sit up and take notice of bird flu. What does that mean?
If you come across a dead bird or if you keep chickens and they die, don’t touch them. And if you consume raw milk, be conscious that there is a risk in doing so.
Early on in COVID, I said, “Don’t panic; do prepare.” There is no reason at present to panic about H5N1. But there is reason to be aware of the outbreak.
What would ring my alarm bells would be any evidence of transmission among humans of the cattle adapted strain, or indeed of any flu virus to which there is not a large amount of immunity in the population.
We have vaccines, and I think it’s a good idea to vaccinate farmworkers and others who might be exposed. That would mean fewer infections that will be more likely to clear quickly and provide fewer opportunities for the virus to get a toehold in humans.
Martin Karplus in 2016.File photo by Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Martin Karplus, pioneering figure in theoretical chemistry, dies at 94
Nobel Prize winner helped transform understanding of molecular systems
Yahya Chaudhry
Harvard Correspondent
January 13, 2025
5 min read
A giant in the field of theoretical chemistry, Martin Karplus was renowned for
Martin Karplus, pioneering figure in theoretical chemistry, dies at 94
Nobel Prize winner helped transform understanding of molecular systems
Yahya Chaudhry
Harvard Correspondent
5 min read
A giant in the field of theoretical chemistry, Martin Karplus was renowned for transforming our understanding of molecular systems, his groundbreaking work in computational modeling, and his contributions to molecular dynamics simulations. He will also be warmly remembered for his mentorship and his devotion to advancing theoretical chemistry research and education across the world.
“Karplus made theoretical chemistry a legitimate field of chemistry,” said Eugene Shakhnovich, a former postdoc in Karplus’ lab who is now the Roy G. Gordon Professor of Chemistry in the Department of Chemistry and Chemical Biology. “His work showed that by doing computational work, without experiments, one can gain great insights and help experimentalists not only understand but also predict outcomes.”
Karplus, the Theodore William Richards Professor of Chemistry, Emeritus, was a member of the National Academy of Sciences, the American Academy of Arts & Sciences, and a foreign member of the Netherlands Academy of Arts & Sciences and the Royal Society of London. He received many honors and awards over his long career, including the Nobel Prize in chemistry. Karplus passed away Dec. 29 in Cambridge at the age of 94.
Interview with Nobel Prize winner Martin Karplus as part of the Experience series.
Born into a Jewish family on March 15, 1930, in Vienna, Karplus’ childhood was interrupted by the rise of the Nazi regime, which forced his family to flee following the Anschluss in 1938. Their refugee journey took them through Switzerland and France before they reached the U.S.
Settling in Greater Boston, Karplus pursued his undergraduate degree at Harvard, graduating in 1951. He earned his Ph.D. at the California Institute of Technology in 1953 under the supervision of Linus Pauling, one of the founders of the fields of quantum chemistry and molecular biology. Pauling, who received the Nobel Prize in chemistry in 1954, recognized Karplus’ talent and potential, describing him as “my most brilliant student.”
Upon earning his doctorate, Karplus completed a postdoctoral fellowship at Oxford before joining the faculty at the University of Illinois Urbana-Champaign, where his research on molecular structure led to the formulation of the widely taught “Karplus equation,” a fundamental principle relating molecular structure to nuclear magnetic resonance data. He moved to Columbia University in 1960, working on chemical reaction dynamics with early digital computers to break new ground.
Karplus addresses the media after winning the Nobel Prize in chemistry in 2013.
Harvard file photo
In 1966, Karplus returned to Harvard as a tenured professor, a position he held for more than five decades. Here, he applied the fundamental laws of physics and chemistry to proteins and macromolecules, envisioning methods to understand life processes.
“Martin was a great unifier of physics, chemistry, and biology, showcasing his broad impact across multiple scientific disciplines,” said James Anderson, Philip S. Weld Professor of Atmospheric Chemistry and a longtime colleague. “History will clarify the fact that he was the backbone of quantum mechanics during its flowering years, from an analysis of the hydrogen atom all the way to the formation of molecules, molecular structures, and the way in which molecules change their structure during a chemical reaction.”
“Martin was a great unifier of physics, chemistry, and biology.”
James Anderson, Philip S. Weld Professor of Atmospheric Chemistry
Karplus made seminal contributions in the field of molecular dynamics, where he developed simulations that allowed researchers to visualize and predict the motion of molecules in complex systems. In 1983, Karplus and his co-authors developed the widely used software program Chemistry at HARvard Macromolecular Mechanics to simulate biological interactions across a wide range of scenarios. Karplus’ innovations transformed the study of chemical reactions and protein folding.
Having long dreamed of working in France, Karplus joined the faculty at the University in Strasbourg, splitting his time between there and Cambridge. In 2013, Karplus, alongside Michael Levitt and Arieh Warshel, was awarded the Nobel Prize for “the development of multiscale models for complex chemical systems.”
In addition to his vital research, Karplus was a dedicated educator who sought to teach chemistry to students at different levels across higher education. His textbook “Atoms and Molecules” has been a mainstay in undergraduate physical chemistry courses for years. He also fostered a robust and international network of scholars who studied in his lab, providing both professional and personal support. Shakhnovich, who was born and trained in the Soviet Union, recalled Karplus’ warm reception when he came to the U.S. in 1990.
“Martin was first person I saw in the United States, because he was kind enough to come to the airport to pick up me and my family,” Shakhnovich said. “His support at the very beginning of my career in this country was absolutely crucial and instrumental.”
Said Anderson of Karplus’ global influence: “His postdocs, graduate, and undergraduate students are found on the faculty of virtually every major university in the United States and Europe. That’s a legacy that speaks for itself, reflecting his profound impact in academia worldwide.”
Dan Kahne, Higgins Professor of Chemistry and Chemical Biology and chair of the Department of Chemistry and Chemical Biology, recalled Karplus’ pioneering research as pivotal.
“He was way ahead of his time, anticipating the importance of the biological tools he was developing to address protein dynamics and folding long before anyone else did,” Kahne said.
Karplus is survived by his wife, Marci; son, Mischa; daughters Reba and Tammy; and granddaughter, Rachel.
Nation & World
Nuclear has changed. Will the U.S. change with it?
The first two nuclear reactors built in the U.S. in decades opened recently, alongside older reactors, at the Vogtle plant in Waynesboro, Georgia.Mike Stewart/AP Photo
Christina Pazzanese
Harvard Staff Writer
January 7, 2025
7 min read
Citing safety improvements and rising demand, analyst expects revival of energy with a checker
Nuclear has changed. Will the U.S. change with it?
The first two nuclear reactors built in the U.S. in decades opened recently, alongside older reactors, at the Vogtle plant in Waynesboro, Georgia.
Mike Stewart/AP Photo
Christina Pazzanese
Harvard Staff Writer
7 min read
Citing safety improvements and rising demand, analyst expects revival of energy with a checkered history
Editor’s note: This story has been updated to reflect that Daniel Poneman served as CEO of Centrus Energy, a supplier of nuclear fuel, from 2015 through 2023.
Fueled by artificial intelligence, cloud service providers, and ambitious new climate regulations, U.S. demand for carbon-free electricity is on the rise. In response, analysts and lawmakers are taking a fresh look at a controversial energy source: nuclear power.
Two new reactors in Georgia are the first in consecutive years in the U.S. since 1990. In June, Congress overwhelmingly passed the ADVANCE Act, a bipartisan bill that boosts the number of reactors coming on line. Late last year, tech giants Google, Amazon, and Microsoft all pledged to invest in small reactors to help meet their future energy needs.
In this edited conversation with the Gazette, Daniel Poneman, a senior fellow at the Belfer Center, discusses the growing momentum behind nuclear power plants. Poneman served as deputy secretary of energy and chief operating officer at the U.S. Department of Energy from 2009 to 2014. From 2015 through 2023 he was CEO of Centrus Energy, a supplier of nuclear fuel to power plants around the world.
Is nuclear power making a comeback?
I believe the answer is yes, because we have new factors present and they’re all converging to add momentum to nuclear. For a long time, a lot of people have been worried about climate change and reducing carbon emissions. The only source of clean power that’s been proven to work — day or night, season in, season out, in any geographic location, and successfully operating at large scale — that’s nuclear. It’s just shy of 20 percent of our total electricity production and nearly half of our carbon-free electricity.
On top of that is this vertiginous increase in electricity demand that’s driven by 1) the AI revolution and 2) the effort to decarbonize not only power generation, which is about one-quarter of total emissions, but also transportation and industrial processes. If you have electric vehicles and you get the power for the vehicles from coal plants, you haven’t solved the emissions problem.
The last factor is the hyper scalers, which have the wherewithal and frankly the balance sheets to support these very substantial investments in nuclear. So, you have all of those market-driven factors and strong recognition by the government of the importance of nuclear. I don’t think there’s any issue that has broader or deeper bipartisan support than this one. All of these things are converging to add new momentum to American nuclear energy.
Historically, opposition to nuclear power has been linked to safety and environmental concerns —including waste— and on the business side, to high costs and low profits. What’s different — is today’s nuclear power safer, cleaner, more cost-effective?
In terms of security, when people were concerned after 9/11, changes were undertaken. And obviously, a lot of lessons were drawn after Fukushima. There has been a continuous set of improvements over the years.
When you ask what’s different: There is a whole new generation called advanced reactors. One of the problems over the years is that large reactors got larger and larger, and each one became a bespoke project. There were too many change orders within a single reactor project, and that just kills you on budget.
One thing is to go to factory-built, small reactors that can be standardized, punched out like a cookie cutter, the same design over and over. The more of these things you punch out, the cheaper it gets, and the more practice you have installing them, the cheaper it gets. If you do things like that, you can improve on safety and budget.
The waste issue depends on the specific reactor technology. Some advanced reactors are based on existing Gen III designs, so their waste would be the same but with smaller quantities because the reactors are smaller. Gen IV reactors use fast neutrons, which allow a more efficient use of fuel and therefore a reduction of total volumes. Some Gen IV reactors can burn used fuel that has already been irradiated, which would have the effect of both burning out some of the minor actinides and turning what is now considered “waste” into a source of more energy. At the end of the day, all nuclear waste, whether from current generation or advanced reactors, will need to be disposed in deep geologic formations; this is a safe process with well-known technology.
“I don’t think there’s any issue that has broader or deeper bipartisan support than this one.”
The Biden administration late last year announced several new U.S. nuclear benchmarks at the United Nations Climate Change Conference. Are those goals realistic?
They’re ambitious, but I think they’re necessary if we’re going to reach our targets. At the Belfer Center, I’m working on a project on how to get 200 gigawatts of new nuclear built in the United States by 2050. A bunch of things have to happen right for that to be achievable. But I have great confidence that when there’s something that’s truly important, and people in the United States put their minds to it, we can do great things. But it’s going to take smart government policies. We’re going to have to have lean and effective regulations. We’ve got to figure out a way to spread the cost and risk sufficiently, so you induce people to act sooner rather than later.
Government loan guarantees that reduce the cost of capital can both defray first-mover risks and also give confidence to the private sector to co-invest. If we concentrate our efforts, we have a chance to restore U.S. global leadership.
What factors will determine whether those goals are reached or derailed?
Government is going to have to be there in terms of smart tax policy, in terms of providing things like cost-overrun insurance. The government also can be an important source of demand, especially for small and micro reactors that have potential applications such as supporting micro grids for things that can’t afford to go dark — military bases, things of that character. If there’s a cyber threat from an enemy or from some natural event, I would recommend the government buy a bunch of these small reactors to help them get over that first-of-a-kind challenge that is so hard to overcome for private entrepreneurs who can’t wait decades for an adequate return on investment. Private capital can then take the confidence that comes from having strong co-investment and commitments from the federal side.
You’re going to have to have the engineering, procurement, and construction contractors who got rusty over the last few decades get back into the game and execute well. And we’re going to have to have the talent pool grow and training programs at the university level, but also in the trades and organized labor. Many thousands and, ultimately, hundreds of thousands of jobs are needed.
You’re going to need well-trained people in the supply chain manufacturing these very precise components and parts. It’s going to take a group effort. And to maintain the social license to do this, we have to bring all of civil society along with us. So far, in recent years, you see a lot of very positive movement in that direction.
Landon Hughes, lead author on the study.
Health
Gender-affirming care rare among U.S. youth, study says
Fewer than 1 in 1,000 received hormones or puberty blockers
Maya Brownstein
Harvard Chan Communications
January 6, 2025
3 min read
Puberty blockers and gender-affirming hormones are rarely prescribed to U.S. transgender and gender diverse (TGD) adolescents, according to a new study from
Gender-affirming care rare among U.S. youth, study says
Fewer than 1 in 1,000 received hormones or puberty blockers
Maya Brownstein
Harvard Chan Communications
3 min read
Puberty blockers and gender-affirming hormones are rarely prescribed to U.S. transgender and gender diverse (TGD) adolescents, according to a new study from researchers at Harvard T.H. Chan School of Public Health, Harvard Pilgrim Health Care Institute, and FOLX Health.
The study was published Monday in JAMA Pediatrics.
“The politicization of gender-affirming care for transgender youth has been driven by a narrative that millions of children are using hormones and that this type of care is too freely given. Our findings reveal that is not the case,” said lead author Landon Hughes, Yerby Fellow in Harvard Chan School’s Department of Epidemiology and postdoctoral fellow at Harvard Chan School and Harvard Pilgrim Health Care Institute’s LGBTQ Health Center of Excellence.
A 2024 study led by researchers at Harvard Chan School and Harvard Pilgrim Health Care Institute documented the rarity of gender-affirming surgeries among adolescents. But little is known about hormone use among transgender and gender-diverse adolescents. The researchers analyzed private insurance claims data from 2018 to 2022, representing more than 5.1 million young patients ages 8 to 17. They identified transgender or gender-diverse patients based on a gender-related diagnosis and then checked if they received puberty blockers or gender-affirming hormones. They then calculated the rate of adolescents who are TGD and receiving this care per 100,000 privately insured adolescents according to age and sex assigned at birth.
The study found that less than 0.1 percent of minors with private insurance are TGD and received puberty blockers or gender-affirming hormone treatment. No TGD patients under age 12 were prescribed gender-affirming hormones. Use of puberty blockers and gender-affirming hormones was more common among TGD adolescents assigned female sex at birth than those assigned male sex at birth.
The researchers noted that higher rates of puberty blocker and hormone prescriptions for TGD patients assigned female sex at birth aligned with an earlier onset of puberty for people who are female vs. male sex assigned at birth.
“Our study found that, overall, very few TGD youth access gender-affirming care, which was surprisingly low given that over 3 percent of high school youth identify as transgender,” said senior author Jae Corman, head of analytics and research at FOLX Health. “Among those that do, the timing of care aligns with the standards outlined by the World Professional Association for Transgender Health, the Endocrine Society, and the American Academy of Pediatrics.”
The researchers also noted that the study likely reflects the highest rates of puberty blocker and hormone use by adolescents, given the study used private insurance data, likely reflecting greater access to gender-affirming care. Lower rates would be expected among the uninsured, Medicaid recipients, and those with less comprehensive private insurance.
Isa Berzansky, research analyst at Harvard Pilgrim Health Care Institute, and Brittany Charlton, associate professor in the Department of Epidemiology at Harvard Chan School and founding director of the LGBTQ Health Center of Excellence, were co-authors.
Assistant professor of sociology at Howard University, Nicole Dezrea Jenkins is one of four visiting professors from Historically Black Colleges and Universities. Niles Singer/Harvard Staff Photographer
Campus & Community
Natural Black hair, and why it matters
Visiting Howard sociologist gathering data for global research project on cultural, economic, legal significance of styles, textures
Nikki Rojas
Harvard Staff Writer
Assistant professor of sociology at Howard University, Nicole Dezrea Jenkins is one of four visiting professors from Historically Black Colleges and Universities.
Visiting Howard sociologist gathering data for global research project on cultural, economic, legal significance of styles, textures
Nikki Rojas
Harvard Staff Writer
4 min read
During a recent research trip to Cuba, sociologist Nicole Dezrea Jenkins was stopped on the street by three teary-eyed local women. The women — just a few of the dozens around the world whom Jenkins will speak to as part of her Global Crowns Project — thanked her for sharing their stories and caring about their experiences.
“There is something about having an exchange where there is an interpreter in between us but we can still connect,” she said. “It’s really powerful.”
As a qualitative researcher, Jenkins, an assistant professor of sociology at Howard University, conducts interviews and focus groups to gather and analyze data on Black women’s lives. This year, she is in the Faculty of Arts and Sciences’ Sociology Department — one of four visiting professors from Historically Black Colleges and Universities (HBCUs) supported by the FAS and the Harvard & the Legacy of Slavery Initiative — pursuing research on the cultural significance of natural hair and working on her first book.
“African American students of mine have talked about their hair, and a lot of experiences around their hair being something that is different from other young people’s hair,” said Mary Waters, John L. Loeb Professor of Sociology and interim department chair. “But it wasn’t until I sat down with Nicole that I really understood — not only that this is an interpersonal issue and an identity issue, but also the far-reaching effects of African American women’s hair and the fact that it’s legal to discriminate against somebody based on their hair. I was blown away when she told me about that!”
Laws vary by jurisdiction, but presently 25 states have enacted the CROWN Act (Creating a Respectful and Open World for Natural Hair), a law that prohibits race-based hair discrimination, and two states have passed an executive order inspired by the legislation.
Jenkins is traveling to different countries — including France, Brazil, and Cuba — to interview Black women about their experiences wearing natural hairstyles and textures.
“The research I’m conducting right now is very intimate. Women are sharing experiences with me that bring out so much emotion,” she said. “I’m hearing stories of joy, where I’m busting out laughing with my participants. I’m also having moments where I’m tearing up because a woman is crying because she’s sharing a story with me about how someone made her feel terrible or embarrassed her.”
As part of her work, Jenkins has incorporated AI to help her during and after the interview process, particularly for those conversations conducted in languages other than English. “With these multilingual interviews, the use of AI makes this a nearly seamless process,” she said.
As a researcher, Jenkins not only leverages AI tools for translation and transcription, but also helps her with coding.
“Along with the interviews, we want to identify patterns in what folks are saying, and AI technology can do that really well. This is not something that is just easily a one-off and it’s done,” she explained. “You have to really work. AI is like a calculator; you have to know what numbers to input and what problem you’re solving. To use AI the same way, you have to know how to prompt the AI work with these tools.”
Jenkins acknowledged that some scholars are hesitant to employ AI, but she encouraged them to embrace the tools for their scholarship.“I’m hoping that researchers will use these tools not just to save money … but to be able to expand the scope of what we could do by saving costs in these other areas,” like transcription and translation, she said.
While at Harvard, Jenkins is also working on a book based on a two-year ethnography project she conducted at an African braiding and weaving hair salon in Las Vegas. With a semester under her belt, Jenkins said the resources she’s been provided at Harvard for her book and research have “propelled me to be very productive.”
She and Waters underscored the importance of scholarly exchanges between HBCUs and institutions like Harvard.
“I’m really hopeful that these exchange programs will set up longer-lasting relationships, so that we can visit each other and share our research,” Waters said.
“The exchange between faculty and students in these collaborations is really important for a number of reasons. Providing opportunities for networking across institutions provides more opportunities for collaborative work, whether through research publications or teaching. There’s a lot to learn from HBCU faculty, and students from Harvard could really benefit from being exposed to them,” Jenkins added.
Nation & World
Unfuzzy math: U.S. needs to do better
Ed School expert has some ideas, including a rethink of homework bans, after ‘discouraging’ results
Liz Mineo
Harvard Staff Writer
December 19, 2024
6 min read
The latest results of the Trends in International Mathematics and Science Study show that U.S. students’ math scores trail those of many of their global peers. They also re
Ed School expert has some ideas, including a rethink of homework bans, after ‘discouraging’ results
Liz Mineo
Harvard Staff Writer
6 min read
The latest results of the Trends in International Mathematics and Science Study show that U.S. students’ math scores trail those of many of their global peers. They also reveal that U.S. math scores were lower in 2023 than they were in 2019. The test was given last year to fourth- and eighth-graders around the world.
In this edited conversation with the Gazette, Heather Hill, Hazen-Nicoli Professor in Teacher Learning and Practice at Harvard Graduate School of Education, details a “disappointing picture,” including the damage inflicted by pandemic learning loss, and offers ideas on how schools and students might rebound.
How do you interpret these results?
They first show that the U.S. is not where it wants to be in terms of these international comparisons. They also show that the work that we’ve put in over the last 20 to 30 years to try to improve our standing internationally has not paid off. There are not a lot of surprises here because we’ve been also seeing the same signal coming from the National Assessment of Educational Progress. It is a disappointing picture. If you think about kids sitting in classrooms who are going to graduate without being able to reason mathematically or apply mathematical concepts to new problems, it’s just discouraging.
How much of the decline has to do with pandemic learning loss?
A large majority of the decline is due to COVID. Many kids, particularly our most disadvantaged children, lost half a year of math learning because they weren’t in school or they were in a hybrid learning situation. A couple of things about this. First, while the majority of this learning loss occurred at the beginning of the pandemic, teachers reported that even after schools were back to in-person learning, students had forgotten how to “student,” meaning they had forgotten how to attend to instruction, how to do homework in a timely manner, and had lost ground on some of the positive social behaviors that we expect in classrooms. I think most teachers would say that things are now back almost to where they were before COVID, with maybe the exception of cell phones being so distracting for children, but it took several years.
Second, math is cumulative, and students who missed half a year of math are going to struggle to learn new material. A student who has not learned basic fractions in the fourth grade is going to have trouble with more sophisticated fractions in the fifth, sixth, and seventh grades, and when they reach algebra, they are going to have trouble with equations that contain rational expressions. And this leaves teachers struggling with the dilemma of whether to present new material or to spend time helping kids finish up the learning they didn’t quite get through during COVID. Math teachers’ time with their students is limited, and many teachers feel this dilemma acutely.
“Kids’ primary pathway to learning math is in school, and the only way to improve math instruction is through the constant improvement of what happens between teachers and students.”
Heather Hill.
How would you describe the state of math education in the U.S.?
It is highly variable. When I watch classrooms, I see some teachers knocking it out of the park — meaning I see kids talking about the math, solving sophisticated problems, and applying mathematics to new situations. And in other cases, the math is not taught very crisply, in the sense that the lesson might be a little bit conceptually disorganized, or the math may be hard to understand. Many teachers have a mix — a fair amount of student reasoning but also some disorganization around the mathematics.
Another thing is that the pandemic has changed the teaching labor force in the U.S. There are many more novice teachers, and they are therefore inexperienced with the math curricula.
One of the things that’s been promising is that in the last eight or nine years, there’s been more of a focus on high-quality curriculum materials and getting those in front of teachers, and having teachers learn how to use them and adapt them smartly for their children. As this movement continues to build steam, I’m hopeful that we will see improvements in math classroom quality.
Why is math so hard for so many U.S. children?
Some of this is about social pressure. Kids take in the messages that they hear from society about math. It’s common to hear messages like, “Oh, I’m not good in math” from friends or, from adults, “It’s OK not to be good in math; you’ll find something else to do.” Whereas in many other countries, math is seen as a prerequisite to a good life, and the understanding that even if it is a hard thing, you’re going to invest in it, and you’re going to do well.
Also, for many kids, math feels very foreign. They don’t see people like them doing math, and what happens in their math classroom doesn’t connect to their own interests and knowledge. Recently, scholars in my field have begun to think about how to revise curriculum materials so that they feature, for instance, mathematicians from other cultures or successful doers of math that look like the kids that are learning math.
Finally, we’ve moved away from giving students opportunities to practice the mathematics they’ve learned in class. This move comes from two sources: curriculum materials whose lessons contain little time for practice, and recent homework bans. Many of the homework bans are predicated on concerns about children’s unequal access to caregiver support for homework as well as concerns that some schools assign too much homework. But for a content area like math, it matters that kids have a chance to practice what they’ve learned in class.
How can the U.S. education system help students improve their math scores?
One thing that could help is changing the narrative about mathematics from one that says, “It’s OK if you don’t do well in math” to one that says, “If you work hard, you’re going to learn math because it’s logical and there is help.” There are ways everybody can learn math.
Working on teacher-student relationships can, maybe surprisingly, assist with math learning. When teacher-student relationships are strong, they result in better outcomes for kids across the board. In math, one reason may be that teachers can more easily engage kids in the work.
There’s such a scarcity of math teachers, which is driving some of the instructional quality issues. We have teachers who don’t have a background in math teaching math, and we also have folks without a background in teaching or math teaching math. Solving teacher pipeline issues is also key.
Kids’ primary pathway to learning math is in school, and the only way to improve math instruction is through the constant improvement of what happens between teachers and students. This means continuing to work on the quality of curriculum materials and engineering ways to enhance instruction.
Bob Dylan recording his first album, “Bob Dylan,” in November 1961 at Columbia Studio in New York City.Michael Ochs Archives/Getty Images
Arts & Culture
Voice of a generation? Dylan’s is much more than that.
Classics professor who wrote ‘Why Bob Dylan Matters’ on the challenge of capturing a master of creative evasion
Sarah Lamodi
Harvard Correspondent
December 19, 2024
6 min read
“A
Voice of a generation? Dylan’s is much more than that.
Classics professor who wrote ‘Why Bob Dylan Matters’ on the challenge of capturing a master of creative evasion
Sarah Lamodi
Harvard Correspondent
6 min read
“A Complete Unknown,” James Mangold’s new film about Nobel laureate Bob Dylan, will be released in the U.S. on December 25. Based on Elijah Wald’s 2015 book, “Dylan Goes Electric! Newport, Seeger, Dylan, and the Night That Split the Sixties,” the film, with Timothée Chalamet starring (and singing) in the lead role, depicts Dylan’s life from his 1961 arrival in New York to his controversial electric set at the Newport Folk Festival in 1965.
Mangold’s movie has been nominated for three Golden Globes, praised by critics, and blessed by Dylan himself, but the judgment of audiences, including hardcore fans, awaits. How to portray an artist who seems to take pride in his talent for evasion? And why try?
In this edited conversation with the Gazette, Richard F. Thomas, the George Martin Lane Professor of the Classics and author of “Why Bob Dylan Matters,” discusses Dylan’s complex career, his singular voice, and his lasting impact as a songwriter and performer.
Dylan’s voice is extremely important to his music. How hard is it to get that voice right?
Dylan never strives to recover in performance the sound of a studio album. The crowd may want to hear what they heard when they first dropped the needle on the record. Dylan’s not interested in that. Dylan is interested in the living song, and so, the living song will change from performance to performance. Take a great song like “Don’t Think Twice, It’s All Right,” and that final verse. Now, if you say it: “Don’t think twice, it’s all right,” that gives the song a certain meaning. If you sing “Don’t think twice, it’s all right,” that gives the song a very different meaning, both in its last verse and back onto the whole song. Dylan constantly is doing that. He’s upsetting audience expectation of the lyrics themselves, which change in performance as well as in drafts. He’s an oral poet in that way.
Should we be looking for an exact Dylan impression in this film? Is it possible to accurately depict someone who has never wanted to be categorized?
I think it’s a challenge. Dylan was a little more open, though still dealing with the personas, in the early years. It’s in some ways easier to capture the Dylan of ’61, ’62, ’63, even though we don’t have much documentation of him. He was clearly concerned to not reveal too much from an early stage, but that of course intensified as he as he said himself, “I’m only Bob Dylan when I have to be.” That’s why I liked Todd Haynes’ movie [“I’m Not There,” which came out in 2007]. I thought Haynes’ way of dealing with the personae by having different characters of different ages and races and even gender playing Dylan was a brilliant move. Obviously, Mangold went at it more directly. That’s a greater challenge, in a way.
Timothée Chalamet as Bob Dylan in “A Complete Unknown.”
Photo by Gotham/GC Images
What are your expectations for the film?
I don’t really care that much about the lived everyday life of Dylan as, partly from being a classicist, my poets have been dead for 2,000 years, and most of the biographical information is invention about them. Invention, from a century or more later, after they’d been classics, after they were being taught in the schools. Now, with Mangold, he sat down and I guess had two or three long conversations with Dylan and, from what I’ve read, Dylan told Mangold a few things that are not known from those years. So, will those be in the movie? And if so, will they reflect reality and truth, or will they reflect what Dylan was creating in 2023 or 2024, whenever he spoke to Mangold? Even the new biographical detail that we may get in the movie will not necessarily be reliable because it may well be a creative act by Bob Dylan.
Even if I personally end up being slightly disappointed, that won’t mean that the movie has failed. I don’t think it’s made for people like me. It’s made to depict a lifetime, or just a slice of a lifetime of the genius of our age, in terms of use of the English language in song.
After 20 years, why continue teaching a course on Dylan?
It’s partly the lyrics. He’s a poet; the lyrics are enduring. They’re not tied to a chronological moment or a political or cultural moment, they’re about issues that are enduring, that repeat over time, over history. Is that partly me, because I have followed Dylan so closely, whereas I haven’t necessarily followed or replayed Herman’s Hermits, Gerry & The Pacemakers, or other singers and groups I loved when I was young? Maybe it’s partly that, but I think it’s also Dylan. The classic status is one that establishes itself retrospectively. Dylan’s unusual in that the career continues in new and newly creative ways. There may even be another album — praise God if so! The story is still going on. And even when the story’s over, there will be performances and versions that we haven’t heard.
“Why do I keep teaching Dylan? The same reason I keep teaching Virgil or Horace or Ovid: because it’s great literature, performance, great whatever you want to call it, and it represents the best that human genius can give us. ”
Why do I keep teaching Dylan? The same reason I keep teaching Virgil or Horace or Ovid: because it’s great literature, performance, great whatever you want to call it, and it represents the best that human genius can give us. That’s a gift that we should treasure and keep passing on as long as we have breath to do so.
Science & Tech
A small slice of time
This video shows Rubin’s Simonyi Survey Telescope in action, taking on-sky observations with the 144-megapixel test camera called the Commissioning Camera.Credit: RubinObs/NSF/DOE/NOIRLab/SLAC/AURA/Hernan Stockebrand
Clea Simon
Harvard Correspondent
December 19, 2024
5 min read
An NSF project builds a special camera to shoot the night sky, light up dark mat
This video shows Rubin’s Simonyi Survey Telescope in action, taking on-sky observations with the 144-megapixel test camera called the Commissioning Camera.
An NSF project builds a special camera to shoot the night sky, light up dark matter, and map the Milky Way
The night sky is now a little clearer.
With the ultimate goal of creating a comprehensive map of the universe, the 10-year Legacy Survey of Space and Time project passed a major milestone in October when its testing camera at the NSF-DOE Vera C. Rubin Observatory captured its first images of the night sky.
“With on-sky images obtained with our engineering camera, Rubin Observatory demonstrated that the Simonyi Survey Telescope and Rubin software frameworks are operational,” said University of Washington Professor Željko Ivezić, the observatory’s construction director.
As the team makes regular updates, its members are “excited about our next milestone: integrating our main camera, the largest astronomical camera ever constructed, with the telescope,” Ivezić said.
That main imager is the much larger LSST Camera, which will be capable of obtaining images 21 times bigger than the test camera’s. Work is now ongoing to prepare this camera for installation on the Chile-based telescope with the aim of having it up and running by the end of January. A commissioning period of approximately six months will follow, with the first public release of astronomical images expected in mid-2025.
The team plans to “make all the data immediately available to the entire community of scientists, [with] education outreach for K through 12th grade, and participating countries and institutions.”
Christopher Stubbs
Stubbs is currently working with the telescope’s team in Chile.
Credit: RubinObs/NSF/DOE/NOIRlab/AURA/A. Alexov
The LSST camera’s size and resolution are needed for “cosmic cinematography,” said Harvard Professor of Physics and of Astronomy Christopher Stubbs, who is currently working with the telescope’s team in Chile and was Rubin’s inaugural project scientist.
Explaining the project, which was conceived roughly 30 years ago, he said: “Astronomers had built large-aperture telescopes, which collect a lot of light to look at things that are faint. Astronomers had built wide-field telescopes that can look at a lot of things at the same time. The idea here was to put those two things together and make a wide-field, large aperture telescope that can look at lots of faint things all at once.”
By scanning the sky every few nights for 10 years with such a powerful telescope and camera, the observatory will garner “a time-lapse image of the sky every single night and look for everything that changes or moves,” Stubbs said.
The project, which is funded by the U.S. National Science Foundation and U.S. Department of Energy’s Office of Science, breaks ground on two fronts. The first, said Stubbs, is philosophical, as the team plans to “make all the data immediately available to the entire community of scientists, [with] education outreach for K through 12th grade, and participating countries and institutions.”
“The idea of completely wide-open data set is a new way of doing business,” he said.
The project is revolutionary in another way as well, said Stubbs, author of “Going Big: A Scientist’s Guide to Large Projects and Collaborations.” Previously, “people would point the telescope at their favorite object,” a particular galaxy or star. The wide field of the new telescope and its camera makes such a tight focus unnecessary. “The same stream of images will serve a wide span of scientific appetites, ranging from finding potentially hazardous killer asteroids in the solar system to mapping out the structure of our Milky Way to finding exploding stars halfway across the universe” he said.
The breadth and duration of this 10-year project may help unlock other secrets, such as the nature of dark matter and dark energy. Dark matter, Stubbs said, is the name we give to “90 percent of the mass of the Milky Way.”
“We infer its existence from its gravitational effect on things,” said Stubbs. So far, however, scientists have been unable to exactly define dark matter. Dark energy is a similar catch-all term for a force not yet identified, but which is making the universe expand “faster and faster and faster,” he said.
“With this instrument and system, which can do a super-precise job on calibration, we’re optimistic about our ability to look at dark matter and dark energy with unprecedented resolution.”
Ideally, the project will shed light on these mysteries and more. “This is the first instrument that we’ve really engineered from scratch to maximize our ability to study open questions in fundamental physics with astrophysical tools,” Stubbs said.
“The initial plan is to collect data for a 10-year period and process that through computer centers in California and in France, and then disseminate those results as broadly as we possibly can and empower both the formal astronomical community and informal education to make the most of this data set.”
Nation & World
What to expect when you’re elected
Professor Jonathan Zittrain leads a discussion, “Implications of Artificial Intelligence,” with newly elected members of Congress.Photos by Martha Stewart
Christina Pazzanese
Harvard Staff Writer
December 18, 2024
5 min read
Bipartisan group of lawmakers gets to know Washington by way of the IOP
Starting a new job can be intimidating
Professor Jonathan Zittrain leads a discussion, “Implications of Artificial Intelligence,” with newly elected members of Congress.
Photos by Martha Stewart
Christina Pazzanese
Harvard Staff Writer
5 min read
Bipartisan group of lawmakers gets to know Washington by way of the IOP
Starting a new job can be intimidating and stressful — what are the unwritten rules, whom can I ask for help? Similarly, the first day of school can be both exciting and a little daunting — will I do well, where will I sit at lunch? Combine the two and you have a sense of what newly elected members of Congress are experiencing right now.
Every two years since 1972, the Institute of Politics has attempted to ease that transition by inviting first-year lawmakers to Harvard Kennedy School for an intensive three-day briefing about what they can expect once they’re sworn into office.
This year’s program, held Dec. 8-10, offered 37 new members from both parties an opportunity to talk to current and former lawmakers and hear from Harvard faculty on key domestic and international policy topics such as economics, national security, and artificial intelligence. The event included an address by Kennedy School Dean Jeremy Weinstein, who also took questions.
The institute’s director, Setti Warren, said that fostering bipartisanship is one of the conference’s main objectives.
“Bringing people from across the aisle together … is extremely important to us, giving them an opportunity to forge relationships in a place that’s not Washington, D.C.,” he said.
John Mannion of New York and Sarah McBride of Delaware.
Veteran lawmakers such as Republican Dan Crenshaw of Texas and Democrat Cheri Bustos of Illinois (who held office from 2013 to 2023) provided new members guidance on media coverage, effective messaging, and how to manage relationships with their new “classmates.”
“One of the things that was particularly important … was the message that that we heard time and time again from current and former members about the importance of kindness and collegiality toward our colleagues on the other side of the aisle,” said Representative-elect Sarah McBride, a Delaware Democrat.
The first openly transgender woman elected to Congress, McBride was the focus of national news coverage when Speaker Mike Johnson changed House rules at the urging of some Republican lawmakers to restrict restrooms to biological sex.
“Just as Americans every single day go into workplaces with people with different backgrounds and different perspectives but find a way to work together with kindness and collaboration,” said McBride, “we too should summon that basic common sense and basic common decency to work with our colleagues, regardless of our party affiliation or ideology in ways that reflect the kind of diversity of thought and diversity of experience that we see in workplaces across the country.”
Representative-elect Michael Baumgartner, M.P.A./I.D. ’02, a Republican in Washington state’s 5th district, said that while he’s “really proud” to be an HKS graduate, he was hesitant to publicize that he was attending because of what he called the School’s “unwelcoming reputation” on the right when it comes to conservative viewpoints.
IOP Director Setti Warren (left), Missouri Democrat Wesley Bell, Colorado Republican Jeff Hurd, and Florida Republican Mike Haridopolos.
“And so, I was really pleased to hear the dean recommit to viewpoint diversity and intellectual diversity and to making sure that conservative Republicans feel like they have a place at the Kennedy School, too,” he said.
While looking forward to Republican control of Congress and the White House, Baumgartner noted the party’s razor-thin margin in the House and also the temporary nature of political victories.
“So, even though we’re going to be in charge this session, it may not always be that way,” he said. “And I hope some of the contacts and relationships that I made at the Harvard orientation will be helpful in the event that we’re not in the majority.”
Representative-elect Janelle Bynum, a Democrat who flipped a Republican-held seat in Oregon’s 5th district to become the state’s first Black member of Congress, said that there were two panels she found “very helpful.”
“The first was the one on AI. That just spun up a lot of different thoughts like moral authority and who gets to participate in that research or in that ecosystem; the financial impact of what’s being developed in AI.
“I’m always thinking, ‘How can we use a technology that may not be being deployed to our benefit right now, but how can we shift that or how can we [get it to] do more good than it is doing?” said Bynum, who also credited a talk about polls and Gen Z voters with John Della Volpe, the IOP’s director of polling.
Asked about her hopes for the new Congress, Bynum said, “The key word that has been emerging for me is governance. I hope Democrats and Republicans take seriously the need to govern” rather than squabbling or attention-seeking.
Panelists Dov Waxman, University of California, Los Angeles (from left), Rebecca Kobrin, Columbia University, Anna Shternshis, University of Toronto, Maurice Samuels, Yale University, and Derek J. Penslar, Harvard University.Photo by Ilene Perlman
Nation & World
Defining and confronting campus antisemitism
Scholars in Jewish Studies say education, conversation can bolster efforts to defeat hate
Christy DeSmith
Harvard Staff Write
Panelists Dov Waxman, University of California, Los Angeles (from left), Rebecca Kobrin, Columbia University, Anna Shternshis, University of Toronto, Maurice Samuels, Yale University, and Derek J. Penslar, Harvard University.
Scholars in Jewish Studies say education, conversation can bolster efforts to defeat hate
Christy DeSmith
Harvard Staff Writer
5 min read
Jewish Studies faculty from eight North American universities came to Harvard this month to discuss rising antisemitism on their campuses.
The half-day conference, convened Dec. 10 by Derek J. Penslar, the William Lee Frost Professor of Jewish History and director of Harvard’s Center for Jewish Studies, kicked off with a panel discussing campus challenges during the 14 months since Hamas’ Oct. 7 massacre. Professors whose schools experienced high-profile protests in the spring touched on everything from media coverage to hidden gender dynamics within student activism. On the topic of antisemitism, the scholars said that the worst animus has been directed at Israeli students, staff, and faculty, while members of the broader Jewish community have endured targeted pressure to denounce Israel.
“What we’ve seen over many years is growing anti-Zionist sentiment on many college campuses, which often becomes a kind of anti-Israelism,” said Dov Waxman, professor of Israel studies and director of the Y&S Nazarian Center for Israel Studies at the University of California, Los Angeles. “In other words, it’s not just a principled demand for equal rights for Palestinians. It’s not just an opposition to Israel as a Jewish state … but an aversion to anything to do with Israel or anybody associated with Israel.”
Maurice Samuels, a French professor at Yale and director of the Yale Program for the Study of Antisemitism since 2011, emphasized an urgent need for Jewish studies curricula amid the emergence of a “new antisemitism.”
“How are student protesters supposed to know that they’re recycling tropes of classical antisemitism if they’ve never studied those tropes? We need to provide that education.”
Maurice Samuels, director of the Yale Program for the Study of Antisemitism
Classic forms of antisemitism, he said, excluded Jews for their supposed racial difference. “By contrast, the new antisemitism would be more likely to accuse Jews themselves of being racist for supporting what they see as a Jewish ethnostate in Israel,” said Samuels, who has pushed to include antisemitism in campus conversations on race.
Related to these issues, he added, is the place of anti-Zionism in competing definitions of antisemitism. Some organizations, like the International Holocaust Remembrance Alliance, equate all forms of anti-Zionism with antisemitism, while other groups allow for various shades of distinction. The definitions converge around anti-Zionist expression that relies on the racist tropes of classic antisemitism, Samuels said.
“We’ve all seen examples of this over the past year, in which hoary conspiracy theories about Jews controlling finance and the media are trotted out to protest against Israel along with signs and symbols from the Nazi era,” he said. “Are all of these kinds of protests antisemitic? Are some of them? How are student protesters supposed to know that they’re recycling tropes of classical antisemitism if they’ve never studied those tropes? We need to provide that education.”
Picking up on the themes of anti-Zionism and anti-Israel bias was the University of Toronto’s Anna Shternshis, who directs the Anne Tanenbaum Centre for Jewish Studies. Shternshis, whose campus has seen increased calls to halt collaborations with Israeli researchers and institutions, has heard from Israeli graduate students who were dropped by their advisers and from others who felt pressured to condemn their own family and friends living in Israel.
“It doesn’t matter what political views they had,” Shternshis said. “People with Israeli names, Israeli accents — they were immediately put on the stand.”
On the positive side, the school’s Jewish community has united like never before, she said, including through collaboration on their own definition of antisemitism. Shternshis excerpted one of the statement’s key passages: “Using ‘Zionist’ or ‘Zionism’ as a proxy for ‘Jewish’ or ‘Judaism’ does not excuse discriminatory or harassing actions.”
The conference featured a second session on teaching Jewish studies in a time of crisis, with faculty from Fordham, Princeton, Brandeis, and the University of California, Berkeley, stressing the need to bolster civil discourse skills for the classroom and beyond. Penslar, who also co-chairs Harvard’s Presidential Task Force on Combating Antisemitism and Anti-Israel Bias, ended both sessions by fielding audience inquiries on everything from the role of advocacy and “safe spaces” to why some U.S. universities have struggled far less with antisemitism.
Rebecca Kobrin, an associate professor of American Jewish history and co-director of Columbia University’s Institute for Israel and Jewish Studies, picked up on the last topic by praising Dartmouth College, highlighting its popular course on the Arab-Israeli conflict, co-taught by two scholars with complementary expertise in Jewish and Middle East Studies.
“What happens in the classroom is how you change the narrative,” Kobrin said. “It is really helpful to have a class where two professors show that there are two opposing views — and the students have to learn to talk to each other about it, just like the professors.”
Nation & World
Are reparations the answer?
Marcus Hunter (from left), Daniel Fryer, Christopher Lewis, Debora Spar, Erin Kelly, and James Gibson.Photos by Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
December 18, 2024
3 min read
Harvard symposium explores case for restitution to Black Americans legally, economically, ethically
In 2021, the city of Evanston
Marcus Hunter (from left), Daniel Fryer, Christopher Lewis, Debora Spar, Erin Kelly, and James Gibson.
Photos by Niles Singer/Harvard Staff Photographer
Nikki Rojas
Harvard Staff Writer
3 min read
Harvard symposium explores case for restitution to Black Americans legally, economically, ethically
In 2021, the city of Evanston, Illinois, established a program to make reparations to Black residents for historic housing discrimination. The first phase of the project gave 16 residents $25,000 each for home repairs or property costs.
The Evanston program was one topic explored at the recent Center for Race, Inequality, and Social Equity Studies symposium “Are Reparations the Answer?” in which experts across disciplines explored the case for restitution to Black Americans legally, economically, and ethically.
Daniel Fryer, an assistant professor of law and philosophy at the University of Michigan and a speaker at the forum, praised the Evanston example because it targeted a specific injustice that the city was trying to repair. Fryer argued that practitioners must consider the different avenues to attain justice.
“An essential question is, what are we trying to repair?” said Fryer, who also serves as a board member for the Board of Commissioners’ Advisory Council on Reparations in Washtenaw County in Michigan. “In order to repair something, we need to know what’s broken, and it also helps to know why it’s broken.”
“An essential question is, what are we trying to repair? In order to repair something, we need to know what’s broken, and it also helps to know why it’s broken.”
Daniel Fryer
Christopher Lewis, an assistant professor at Harvard Law School, also called for a need to clarify the distinctions between different types of reparations — under either compensatory justice or utilitarian justice, a moral principle that considers the greater good for the greatest number of people.
Lewis, along with Assistant Professor of Sociology and of Social Studies Adaner Usmani, has conducted research on what is owed to the estates of formerly enslaved people for their forced, unpaid labor. Using historic data on government bond yields, they arrived at a “conservative” estimate of the amount due for unpaid slave labor. The number reached into the quadrillions.
“It’s more wealth than exists in the entire world. That can tell you something about the scope and size of the injustice,” he said. These results prompted Lewis to consider other ways to look at the issue of reparations, including those shared by Duke University’s William Darity Jr., and museum curator Kirsten Mullen, who gave the keynote address earlier in the conference.
Darity and Mullen, founder of Artefactual, co-authored “From Here to Equality,” which focused on how to close the racial wealth gap, suggesting an intraracial redistribution of $16 trillion, with Black American families receiving at least a million dollars each.
Raj Chetty analyzed empirical patterns in Black-white economic disparities in a panel. The William A. Ackman Professor of Economics and director of Opportunity Insights discussed his research on how income evolves across generations for Black children versus white children.
Black children who come from high-income families tend to trend downward in terms of economic mobility as adults, compared to their white counterparts, who tend to remain at the top, he said. “In my view, this is really fundamental to understanding how to close the persistence of racial disparities in the U.S.,” he said.
The economist acknowledged that when conducting this research he had expected racial disparities for communities of color would narrow if individuals had sufficient income. The data proved him wrong, he said. “Understanding what’s happening there strikes me as really crucial to make progress, and addressing those disparities is really fundamental,” Chetty said.
“On Display Harvard,” an hourlong performance undertaken by Harvard students, staff, and community members, captures the audience’s attention in the Calderwood Courtyard at the Harvard Art Museums.Photos by Grace DuVal
Campus & Community
Universal, adaptable, wearable, vulnerable
Grace DuVal
Harvard Correspondent
December 18, 2024
5 min read
‘On Display Harvard’ uses performance, zip ties, to
“On Display Harvard,” an hourlong performance undertaken by Harvard students, staff, and community members, captures the audience’s attention in the Calderwood Courtyard at the Harvard Art Museums.
‘On Display Harvard’ uses performance, zip ties, to bring attention to the UN’s International Day of Persons With Disabilities
As you walk past the columns of the Harvard Art Museums and step into the bright light of Calderwood Courtyard, you see a group of 16 people dressed in white. They are arranged in various positions, some standing, some sitting, some using wheelchairs or crutches. They all are wearing garments made of zip ties — plastic spikes protruding at different angles. The forms drape around each performer’s arms, shoulders, legs. The only sounds to break the silence are the low murmurs from visitors who wend between the performers, watching intently, photographing, taking video. Moment by moment the performer’s movements change, gentle shifts in their body, each gesture intuitively executed slowly and thoughtfully.
The scene you are witnessing is “On Display Harvard,” a durational performance installation presented by the Office for the Arts at Harvard (OFA) Dance Program. A mix of Harvard staff, students, and community members come together each year on Dec. 3 as part of “On Display Harvard,” an annual commemoration of the United Nations’ International Day of Persons With Disabilities. This worldwide social justice initiative, created by physically integrated dance company Heidi Latsky Dance, brings together performers across the spectrum of abilities, ages, sizes, and races, into a singular space.
Founded in 2015, the durational performances of “On Display Harvard” create living sculpture parks that the audience is invited to wander through, viewing each performer up close.
“By exposing the general public to our widely diverse sculpture courts, we are expanding what inclusion looks like,” states the “On Display” website.
The sculptural garments worn during this year’s “On Display Harvard” were created by Harvard Graduate School of Design ’24 alumni Pin Sangkaeo and Benson Joseph, collectively known as (snobs._). Collaborators since they met at the School of Architecture at Syracuse University, for the past three years (snobs._) has created one-of-a-kind wearables for “On Display Harvard.” On its statement, (snobs._) explained that to build the garments for each performer “you have to create something that is universal, but at the same time has the capability to be adaptable. Zip ties are the way that we did the wearables. We pre-model a series of implied poses and where they can be put, and then we lay the pictures out on the wall, and we let [the performers] pick and … we modify it to fit the person better. It’s like sketching at full scale.”
Using more than 8,000 zip ties and taking more than a year and a half to complete, the wearables are part of an ongoing, ever-evolving project for (snobs._). Collaborating with the performers of “On Display” allows the creative team to see and understand their work more profoundly. After the event the performers and designers sat together in the greenroom sharing their performance experiences.
“The feedback is the most important part. There’s a validation that comes in when other people offer all the insights of things that maybe you weren’t thinking about … it’s not possible to do that kind of work without feedback,” noted (snobs._).
Graduate student Sandra El Hadi peers through one of the sculptural garments made of zip ties by Harvard Graduate School of Design alumni, collectively known as (snobs._). The zip ties were reconstituted from an earlier, large-scale sculptural installation exhibited in Harvard Square.
Harvard College student Sarah Yee strikes a durational pose. Each zip tie garment was chosen by the performer and custom-fit to his or her body.
Olivia Schrantz, Harvard student-led dance group coach, closes her eyes during an enduring gesture. (snobs._) ruminated on the intensity of the hourlong performance: “It does something to your mind in a vulnerable state, it forces you to be with yourself for an hour.”
The community was invited to move through the performers during the durational work, allowing each audience member to closely observe the performers’ slow movements and intricate garments.
More than 8,000 tessellated zip ties were linked together to create the wearable art embodied by dancer Jassi Murad.
Sanders Theatre staff member and Extension School student Mindy Koyanis moves her hand in slow, cyclical gestures. Koyanis has performed with “On Display Harvard” multiple times over the years.
Harvard graduate student Jessica Sun assists audience members in a tactile tour of the custom wearables. Guided tours of the garments and performance were provided to all audience members, allowing greater access to the event.Community members engage with the performance from different perspectives in Calderwood Courtyard, taking photos, videos, and quietly discussing the work.
Yarumi González slowly slides off a chair during the performance. “Oftentimes people think ‘On Display’ [is about] staying still and you’re moving slow, but it requires so much control that it actually ends up being more work,” explains (snobs._).
Nicolai Calabria is investigated by an observer’s guide dog as he performs.
Nora Rodas, a community member and undergraduate student at Dean College in Franklin, Massachusetts, moves in and out of her wheelchair throughout the performance.
Harvard retiree Jeffry Pike wears a mask of zip ties. Responding to the wearables provided, Pike chose to put the piece over his face, surprising the designers.
Koyanis focuses intently as she performs.
Local musician Charles Murrell III slowly leans against a pillar of the Harvard Art Museums.
Health
Nature offers novel approach to oral wound care
Slug’s sticky mucus inspiration behind adhesive hydrogel that can seal wounds in wet environment
Heather Denny
HSDM Communications
December 18, 2024
4 min read
A discovery inspired by the humble slug may soon be the answer to managing painful oral lesions associated with chronic inflammatory conditions and sealing surgical wounds in
Slug’s sticky mucus inspiration behind adhesive hydrogel that can seal wounds in wet environment
Heather Denny
HSDM Communications
4 min read
A discovery inspired by the humble slug may soon be the answer to managing painful oral lesions associated with chronic inflammatory conditions and sealing surgical wounds in the mouth.
Scientists at Harvard had been searching for a biomaterial that would hold up in wet conditions — that’s when they turned to Mother Nature for inspiration. When slugs feel threatened, they secrete a sticky mucus that protects them from predators. This mucus has strong mechanical properties allowing it to stick to wet surfaces and stretch about 10 to 15 times its original length.
Inspired by these properties, researchers in the Mooney Lab of the Harvard John A. Paulson School of Engineering and Applied Sciences, and the Wyss Institute for Biologically Inspired Engineering, developed a strong adhesive patch composed of 90 percent water from a natural polymer derived from algae, and present in dental impression materials. The adhesive patch will work on wet surfaces and is not toxic to humans. After finding it successfully stuck to animal tissues, acting as a surgical wound sealing biomaterial in lab testing, their findings were published in Science in 2017.
Now, its applications for oral health and treatment of painful oral lesions may be coming soon to a dental office near you. David Tiansui Wu, D.M.Sc. ’23, instructor of oral medicine, infection, and immunity, has been involved in the development of an adhesive hydrogel patch that can seal wounds and act as an intraoral Band-Aid capable of strong adhesion in wet environments and on dynamically moving surfaces. His work as a postdoctoral research fellow and periodontology resident at Harvard School of Dental Medicine first exposed him to the slug-inspired biomaterial, and connections he made in the Mooney Lab fueled his interest in developing a product for use in dental medicine.
“When I started at Harvard University, I had the privilege of meeting Professor David Mooney, who is a world-renowned expert in tissue engineering and biomaterials and decided to start my doctoral thesis at the lab,” Wu said. “At that time, Benjamin Freedman, a postdoctoral fellow at the lab, was working on the preclinical translation of the tough adhesive hydrogel technology for diverse medical and health care applications, such as hemostasis in general surgery, tendon repair in orthopedic surgery, and wound sealing in dermatology. As a periodontist in training, the possibility of bringing this revolutionary technology from benchtop to patient care appeared to be a great opportunity to solve unmet needs in our field,” Wu said.
“This technology can be applied to seal surgical sites such as gingival graft harvest sites, extraction sockets, bone augmentation surgical sites, and much more.”
David Tiansui Wu
Benjamin Freedman and David Tiansui Wu, the developers of Dental Tough Adhesive (DenTAl).
Wu collaborated with Freedman to advance the preclinical testing and development of the technology and expand its functionality with drug-release capabilities that would allow the hydrogel to deliver a range of medications relevant for dental, oral, and craniofacial applications.
In parallel, Wu and Freedman began working with other faculty collaborators at the Massachusetts General Hospital departments of Oral and Maxillofacial Surgery and of Dermatology respectively, including Fernando Guastaldi and Yakir Levin, to conduct preclinical validation of the adhesive technology in oral applications.
Together, they developed what they call “Dental Tough Adhesive (DenTAl).” Their findings were published in a landmark paper in the Journal of Dental Research, paving the way for the technology’s clinical translation to one day impact patient care.
Chronic inflammatory conditions, such as oral lichen planus and recurrent canker sores, “negatively affect patients’ quality of life,” said Wu. “Current treatment approaches are mainly palliative and often ineffective due to inadequate contact time of the therapeutic agent with the lesions.
“This novel technology has the potential to impact several areas in dentistry, including applications in oral wound repair and regeneration, and drug delivery. In periodontics and oral surgery, this technology can be applied to seal surgical sites such as gingival graft harvest sites, extraction sockets, bone augmentation surgical sites, and much more. Our vision is to one day develop sutureless wound repair,” he added.
This innovative technology is now being translated into the clinical arena through a license for continued development beyond the laboratory. The multidisciplinary team is taking the next steps to bring the technology into the dental office by obtaining clearance from regulatory authorities such as the U.S. Food and Drug Administration.
“My goal as a clinician, scientist, and innovator is basically to bridge the gap between benchtop research and the clinical arena,” Wu said. “We are excited to translate this technology to impact millions of patients and their dentists in improving their oral health.”
Health
Time for a rethink of colonoscopy guidelines?
Mingyang Song. Stephanie Mitchell/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
December 17, 2024
3 min read
Change informed by new findings would help specialists focus on those most at risk, researcher says
A new analysis of nearly 200,000 adults shows that those with a clean result on their first colonoscopy may not n
Change informed by new findings would help specialists focus on those most at risk, researcher says
A new analysis of nearly 200,000 adults shows that those with a clean result on their first colonoscopy may not need another for longer — perhaps significantly longer — than the current recommendation of 10 years.
Colorectal cancer is the nation’s second-deadliest after lung cancer, killing an estimated 52,550 in 2023. While cases among older patients have been declining, younger patients — those 40 to 49 — have seen cases rise 15 percent over the past two decades. Experts aren’t sure of the cause, but in 2021, the U.S. Preventive Services Task Force lowered the recommended age of first screening to 45 from 50. They also recommend that those with average risk get screened 10 years afterward.
Mingyang Song, an associate professor of clinical epidemiology and nutrition at the Harvard Chan School, said that the increase in screenings has also increased appointment wait times.
“Especially with the lowered age, the clinic is overwhelmed,” said Song, also an associate professor at Harvard Medical School. “It was overwhelmed before, now it’s even worse.”
In the research, published last month in JAMA Oncology, Song and colleagues examined colorectal cancer screening results and colorectal cancer incidence among 195,453 participants in three long-running studies: the Nurses’ Health Study, the Nurses’ Health Study II, and the Health Professionals Followup Study. They compared incidence between two groups: those who received negative results in their initial colorectal cancer screening — meaning no polyps or cancer — and those who had not yet been screened.
The researchers found that the risk of developing colorectal cancer was significantly lower among those who had received a negative cancer screening compared with those who had not yet been screened. The research team, led by first author Markus Knudsen, a postdoctoral fellow in Song’s lab, then divided the negative screening result group according to lifestyle risk factors for colorectal cancer. The work was supported in part by the National Institutes of Health.
The results showed that, among individuals with a negative screening result, it took 16 years for those with an intermediate-risk profile to have the same colorectal cancer incidence of the high-risk group at 10 years, and those with a low-risk profile — including maintaining a healthy diet and exercise — didn’t reach the 10-year cancer incidence of the high-risk group until 25 years from their negative screening.
The results, Song said, show that cancer screening should be individualized and discussed between patient and physician. While it is likely that additional evidence will be needed before national screening guidelines are changed, those with a negative screening result may be able to safely extend the screening interval beyond the recommended 10 years and, for those also living a low-risk lifestyle, perhaps as long as 20 years.
What this more tailored approach would do, Song said, is spare those who might get little benefit from a colonoscopy while focusing increasingly scarce resources where they’re most needed: on people who’ve never been screened — only about 70 percent of eligible U.S. adults have been screened — on disadvantaged groups with historically lower screen rates, and on those whose lifestyle or family history puts them at increased risk.
“What we have seen generally is that the more advantaged groups of individuals are more likely to receive colonoscopy, whereas those who are disadvantaged and who actually have a higher risk of developing colon cancer are less likely to receive colonoscopy,” Song said. “We’ve tried to correct this mismatch and improve colonoscopy delivery at the population scale.”
Campus & Community
Three Harvard students named Marshall Scholars
Ryan Doan-Nguyen (from left), John Lin, and Laila Nasher.Photos by Stephanie Mitchell/Harvard Staff Photographer; Grace DuVal; and courtesy of Laila Nasher
Eileen O’Grady
Harvard Staff Writer
December 16, 2024
6 min read
‘Chance of a lifetime’ for recipients whose fields include history, biology, education policy
Three
Ryan Doan-Nguyen (from left), John Lin, and Laila Nasher.
Photos by Stephanie Mitchell/Harvard Staff Photographer; Grace DuVal; and courtesy of Laila Nasher
Eileen O’Grady
Harvard Staff Writer
6 min read
‘Chance of a lifetime’ for recipients whose fields include history, biology, education policy
Three Harvard students will take their passions for journalism, health equity, and education equity to the United Kingdom next year as members of the 2025 Marshall Class. Ryan Doan-Nguyen, John Lin, and Laila Nasher are among 36 students nationwide to receive 2025 Marshall Scholarships, which support two years of study at a U.K. college or university.
Stephanie Mitchell/Harvard Staff Photographer
Ryan Doan-Nguyen
Joint concentration in History & Literature and Government, with a secondary in Ethnicity, Migration, Rights
Doan-Nguyen ’25, of Westborough, Massachusetts, strives to bridge research, writing, and advocacy in journalism and history. Having grown up listening to his family’s stories about fleeing the Vietnam War as refugees, he is passionate about amplifying marginalized voices in his work. His senior thesis includes oral history interviews with 40 Vietnamese refugees impacted by imperialism.
“There’s so much knowledge and innovation and ways of thought and approaching the world that are excluded because of the way in which we value certain voices more than others,” Doan-Nguyen said. “I’m trying to help break that down in the work that I do.”
The night the Mather House resident learned that he had been named a Marshall Scholar, he ran straight to his roommate to share the good news. Then he called his family and his closest mentors.
“It’s the chance of a lifetime, and I did not expect to receive it in the slightest,” Doan-Nguyen said. “I just remember receiving the call and being so overwhelmed with gratitude.”
Doan-Nguyen plans to attend the University of Oxford, where he will study global and imperial history the first year and U.S. history the second year.
Photo by Grace DuVal
John Lin
Human Developmental and Regenerative Biology; secondary in Global Health and Health Policy
Lin ’25, of Boston, wants to know what different rare diseases have in common, and what factors link them together.
As a member of the Greka Lab at the Broad Institute of MIT and Harvard, Lin studies how cells harness cargo receptors to recognize, degrade, or trap misfolded proteins. He has investigated how cargo receptors regulate disease severity in a rare kidney illness and is applying his findings to other rare diseases.
“We’re finding that if you target these cargo receptors, you can clear misfolded protein in each of these diseases, suggesting that these different misfolded proteins are trapped through this common mechanism,” Lin said. “Just by targeting these common pathways, you can resolve many different rare diseases.”
Lin is also interested in using science journalism to make information more accessible to the general public. The Currier House resident said he became passionate about health equity after seeing his parents, working-class immigrants from China, face linguistic and economic barriers in accessing care.
“Even though I was really interested in solving these diseases and at the most direct level through research, I realized through observing my family’s experiences that it’s not just discovering the science that’s important but also getting the science to the people who are impacted by it every day,” Lin said.
Lin was swimming in the Malkin Athletic Center pool when the call came that he had been named a 2025 Marshall scholar.
“I was really surprised,” said Lin, who immediately phoned his mom to share the news. “I’m very, very grateful for the opportunity.”
Lin plans to spend his first year as a Marshall Scholar studying biological sciences at the Wellcome Sanger Institute for genomics research at the University of Cambridge, and his second studying medical anthropology at the University of Oxford.
Laila Nasher
History and Anthropology; secondary in Ethnicity, Migration, Rights
Nasher ’25 wants education to be a protected American right for all students. A first-generation college student, Nasher said that coming to Harvard after attending public school in her low-income neighborhood in Detroit fueled her desire to make change.
“For me it was the question of, why not us?” said Nasher. “Why did I and why did the people in my community never have these types of educational opportunities that are and should be the norm?”
Nasher was in her Mather House dorm room when she got the call that she had received a Marshall, and immediately celebrated the news with her roommate.
“I was just in shock and very, very grateful,” Nasher said.
On campus, Nasher founded the First-Generation Low-Income Task Group, served on the board of Primus, and was co-director of diversity and outreach for the Institute of Politics. Off-campus, she interned with Congresswoman Rashida Tlaib and the Tawakkol Karman Foundation in Istanbul, and organized with the Michigan Education Justice Coalition.
She’ll spend her first year as a Marshall Scholar studying education at the University of Oxford, where she plans to do a comparative study on how primary and K-12 education systems in the U.K. and the U.S. shape the experiences of people in low-income, urban Yemeni communities.
Health
Should pharmacists be moral gatekeepers?
‘The problem is not opioids,’ says author of ‘Policing Patients’ — it’s overdose, pain
Samantha Laine Perfas
Harvard Staff Writer
December 16, 2024
8 min read
Since the opioid epidemic was declared a public health crisis in 2017, it has claimed the lives of nearly half a million Americans. High-profile cases like that against Purdue Pharma
‘The problem is not opioids,’ says author of ‘Policing Patients’ — it’s overdose, pain
Samantha Laine Perfas
Harvard Staff Writer
8 min read
Since the opioid epidemic was declared a public health crisis in 2017, it has claimed the lives of nearly half a million Americans. High-profile cases like that against Purdue Pharma and the Sackler family put the focus on prescription drugs, but the reality is far more complicated, says Elizabeth Chiarello, author of “Policing Patients: Treatment and Surveillance on the Frontlines of the Opioid Crisis” and a former fellow at the Harvard Radcliffe Institute. Over the course of 10 years, she spoke to healthcare workers who face difficult choices between treating and punishing patients, and the problems that have arisen from policing drugs at the pharmacy counter. The Gazette spoke to Chiarello about what she learned. This interview has been edited for length and clarity.
At the beginning of your book, you say the problem is pain, not drugs. Why should pain be centered in conversations about the opioid epidemic?
When we talk about the opioid crisis, we usually categorize two groups of people: those with substance use disorders and those in chronic pain. We act as if these are two different groups of people who have little in common, with the implication that people with pain have a legitimate claim on opioids and the people with substance use disorders do not. Pain is the throughline that connects these two groups. Whether we’re talking about pain from mental health disorders or the pain of trauma, substance use disorders are often a mechanism of self-medication or avoiding pain. People with substance use disorders are often taking opioids not to chase a high, but because they’re trying to avoid the pain of withdrawal.
It’s worth mentioning that when we think about pain, the boundaries we’re willing to set around other people’s bodies are very different than the boundaries we’re willing to set around our own. When we are in pain, we are very eager to stop it, and we’d want any resources available to help us.
“People with substance use disorders are often taking opioids not to chase a high, but because they’re trying to avoid the pain of withdrawal.”
During your research, you were surprised to learn pharmacists are on the front lines of this crisis.
Culturally, pharmacists don’t loom particularly large in our collective imagination; they’re often behind the scenes filling prescriptions and we don’t always know their names (whereas we tend to know a lot about our doctors and are very selective about who we choose). People often believe that pharmacists just dispense whatever it is that the doctor orders. But in fact, they are professionals who work under their own licenses; they have extensive discretion at the pharmacy counter. Pharmacists act as medical, legal, fiscal, and moral gatekeepers; they balance those different gatekeeping roles in different organizational settings, but ultimately decide who receives medications.
Pharmacists use something called prescription drug monitoring programs, or PDMPs. What are they and what role do they play?
PDMPs are two-tiered “big data” surveillance systems. When a patient goes to the pharmacy with a prescription for an opioid, the pharmacist dispenses the medication and then sends that information to the organization that runs the PDMP. It varies from state to state but could include the Board of Pharmacy, the Board of Health, the Department of Justice, or Department of Consumer Affairs. They then partner with a private company that compiles that information and feeds it back to healthcare providers who can use it to make decisions about patient care.
However, they also feed that information to law enforcement, who can use it to make decisions about targeting healthcare professionals and access individual patient data. You might wonder, isn’t this all covered under HIPAA? And the truth is it’s not. PDMPs are not afforded the same privacy protections as other healthcare data. We see both physicians and pharmacists reorienting towards policing, away from care, and toward using this surveillance system. As a result, patients are routed out of healthcare and left incredibly vulnerable.
Credit: Raquita Henderson, Pinxit Photo & Cinema
One aspect of the opioid crisis that has received a lot of media attention is the role of organizations like Purdue Pharma. In what ways has their role — while not to be minimized — become an oversimplification of what’s happening?
The Purdue story has been everywhere; it’s been in bestsellers, movies, TV shows, and in lawsuits. The problem is not that the story is wrong, but that it’s incomplete. It places a lot of blame on the shoulders of a single medication and a single company. What we lose is the last 100 years of drug policy, where we’ve seen the drug policy pendulum swing back and forth between medicalization and criminalization.
For example, at the turn of the 20th century, there were a lot of middle-class, rural housewives who were hooked on opium and it wasn’t considered a social problem. But when Asian men came over to build the railroads, we saw the criminalization of opium. Then in 1914 we passed the first drug law, the Harrison Narcotics Tax Act, that made it illegal to give people medication just for the purposes of preventing withdrawal. Supreme Court cases followed, and we saw the arrests of thousands of physicians and pharmacists that led to a chilling effect around opioids for around 50 years. In the 1980s we had the hospice movement in England that argued people shouldn’t have to die in pain. On the heels of that movement followed the pain-management movement in the United States that said if people shouldn’t have to die in pain, they shouldn’t have to live in pain either. They pushed for increased access to opioids and drew attention to chronic pain patients who had been undertreated for decades.
If you don’t know that story, it seems as if OxyContin came out of nowhere and did an extraordinary amount of harm. But a lot of the increase in prescribing that we saw at the end of the 1990s was really a corrective to underprescribing that had been happening for decades before that.
You go as far as saying that we should reframe the current epidemic as an overdose crisis, rather than one of opioids.
With drug policy, we have a tendency to put our blinders on and focus very narrowly on a single drug or class of drugs. Crack was the problem in the 1980s and ’90s, then meth was the problem in the early 2000s, then prescription opioids, then heroin, and then fentanyl, and now xylazine [also know by street name “tranq.”] But when we treat these as individual, isolated crises, we miss the throughline and the larger story. The problem is not opioids. The problem is overdose. I think we need to talk about it as both an overdose crisis and a pain crisis, because millions of people are suffering in chronic pain and cannot get help.
“We need a three-pronged approach to addressing the overdose crisis, one that’s grounded in treatment, harm reduction, and prevention.”
What stories stuck with you the most during the course of your research?
My dad is a doctor. Hearing what doctors have to say and the ways they feel trapped is hard. And for some doctors, the kind of callousness that they bring to their patients was incredibly disheartening. You know, the doctors who are like, “I tell the patient, I’m going to taper them down, and I don’t care how they feel about it.” Or they stop seeing patients if their urine tests come back positive.
But then there are other physicians like Megan. She worked in a federally qualified health center, which ironically, gave her a little bit more leeway than those who work in private clinics. She had a lot of patients with substance use disorders, so she went out and got the credentials she needed to treat those patients. She had a lot of patients in pain, so she went out and got those credentials. She pushed back on other doctors who were using punitive mechanisms. She was the quintessential patient advocate, and doctors like that really give me hope.
There was a police officer in California who lost his brother to overdose and that drove a lot of the work that he did. He experienced a tragedy, and then his mission became trying to prevent that from happening to other people.
What next steps do you recommend to change our approach to this issue?
We need a three-pronged approach to addressing the overdose crisis, one that’s grounded in treatment, harm reduction, and prevention. When people think about treatment, they often think about either a 28-day inpatient treatment facility or self-help programs like Narcotics Anonymous. But in head-to-head comparisons, we know medications for opioid use disorder are the most effective treatments. We should also expand the types of pain treatment that are available; manipulative therapies like massage and Rolfing therapy can really help.
Then harm reduction. That includes things like Narcan, syringe service programs that provide sterile syringes to people who inject drugs, hotlines like SafeSpot and Never Use Alone, and overdose-prevention sites.
And finally, prevention. I mean capital “P” prevention. We need to uplift our communities and reinforce our social safety net. People have a hard time finding housing, jobs, access to high-quality healthcare. Addressing these issues is an upstream way of dealing with drug crises. Otherwise, we end up with just one crisis after the next.
Go Deeper
Listen to Liz Chiarello’s interview on the BornCurious podcast about the US pain and overdose crises.
Planning a holiday meal and need inspiration? The Schlesinger Library at Harvard Radcliffe Institute has you covered. It holds the papers of the late celebrity chef Julia Child, author of the iconic cookbook “Mastering the Art of French Cooking” and personality behind the long-running PBS television series “The French Chef.” She famously hosted other cooking shows from the kitchen of her Cambridge home. Radcliffe curators helped pull together the following recipes for festive desserts drawn from their vast collection, which includes correspondence, documents, books, photos, audio, and videotapes.
I am particularly fond of the free-form turnover, since one can make it any size and shape, from mini to gargantua. Round is pretty, but either square or rectangular is more practical because it uses less dough and the leftovers are evenly shaped and therefore easily turned into decorations.
For 1 large turnover about 9 by 9 inches (23 x 23 cm), serving 6 to 8
Sweet pie dough (Pate brisée fine, sucrée)
1 ½ cups (215 g) all-purpose flour, unbleached preferred
½ cup (70 g) plain bleached cake flour
1 ½ sticks (6 ounces or 170 g) chilled unsalted butter and 2 tablespoons shortening
2 tablespoons sugar
¼ teaspoon salt
½ cup (1 dL), more or less, iced water
Other ingredients for the turnover
4 to 5 apples that will keep their shape in cooking, such as Golden Delicious, Rome Beauty, Newton, Monroe, Northern Spy
3 tablespoon or more sugar
½ teaspoon, more or less, powdered cinnamon (optional)
The grated rind and the juice of ½ lemon (optional)
1 teaspoon or more melted butter
Egg glaze (1 egg beaten in a cup with 1 teaspoon water)
The dough
Of course you can make the dough by hand or in an electric mixer, but the food processor is sensationally fast and foolproof using these proportions. Proceed as follows: With metal blade in place, measure the flours into the bowl of the machine, cut the butter rapidly into pieces the size of your little-finger joint, and drop into the flour, along with the sugar shortening, and salt. Using the on-off flick technique lasting ½ second, press 7 to 8 flicks, just to start breaking up the butter.
Then, with water poised over opening of machine, turn it on and pour in all but 1 tablespoon of the iced water. Process in spurts, on and off, just until dough begins to mass together but is still rough with some unformed bits. Turn it out onto your work surface and mass together rapidly with the heel of one hand into a somewhat rough cake. (Dough should be pliable — neither dry and hard nor, on the other hand, sticky. Pat in sprinkles more of all-purpose flour if sticky; cut into pieces and sprinkle on droplets more water if dry and hard, then re-form into a cake). Wrap in plastic and refrigerate for at least an hour, to congeal the butter in the dough so that it will roll easily, and to allow the flour particles to absorb the water so that it will handle nicely and bake properly.
May be made 2 or 3 days in advance and refrigerated — but if you have used unbleached flour it will gradually turn grayish; it can still be baked at that point if only mildly discolored since it will whiten in the oven. Or freeze the dough, which is the best plan when you want to have ready dough available; defrost at room temperature or overnight in the refrigerator — dough should be cold and firm for easy rolling.
The apples
Quarter, core, and peel the apples, then cut into thinnish lengthwise slices. Toss in a mixing bowl with sugar and optional cinnamon and lemon rind and juice. Cover with plastic wrap and let macerate for 20 minutes or longer, so that apples will exude their excess juices.
Forming the turnover
(Always work rapidly from here on to prevent the dough from softening; if it becomes difficult to handle, refrigerate it at once for 20 minutes or so, then continue). Roll the chilled dough into a rectangle 20 inches long, and 10 inches wide (50 x 25 cm) and trim off the edges with a pastry wheel or a knife — refrigerate trimmings for decorations later.
Lightly flour surface of dough, fold in half end to end, and center on the buttered pastry sheet. Place a piece of wax paper at edge of fold, and unfold top of dough onto paper. Paint a border of cold water around the 3 edges of the bottom piece and pile the apples onto it, leaving a ¾-inch (2-centimeter) border free at the 3 edges. Sprinkle on more sugar, and a tablespoon or so of melted butter. Flip top of dough over onto the apples, and press edges firmly together, to seal. Turn up the 3 edges all around, then press a design into them (to seal further) with the tines of a table fork and, if you wish, press a decorative edging all around those sides with the back of a knife.
If you have time, it is a good idea at this point to refrigerate the turnover (covered lightly with plastic wrap) for half an hour (or for several hours); it will bake more evenly when the dough has had time to relax, and you, in turn, will have time to turn your leftover bits of dough into a mock puff pastry which will rise into a splendid design.
Mock puff pastry decorations
(Formassedscrapsaboutthesizeof a half tennisball)
Knead leftover raw pastry scraps briefly into a cake, roll into a rectangle, and spread 1 teaspoon of butter down two-thirds of its length. Fold into 3 as though folding a business letter; repeat with another roll and fold (but omit butter) 2 more times. For the simple decorations I used on this turnover, roll out again into a rectangle about 10 inches (25 centimeters) wide. Refrigerate, covered, until ready to use.
Decorating and baking the turnover
Preheat oven to 400°F/200°C. Paint top of turnover lightly with cold water. To simulate wrapping ribbon for your turnover “parcel,” crisscross 2 strips of dough, laying them from corner to corner, lay 1 crosswise from top to bottom, and a final one horizontally. Loop the final strip into a loose knot and place on top. Pierce 2 steam holes 1/16 inch (¼ centimeter) in diameter in top of dough with the point of a knife, going down through the dough to the apples. Paint top of dough and decorations with a coating of egg glaze, wait a moment, and paint on another coat. (Egg glaze goes on just the moment before baking). Make crosshatchings in the glaze with the back of a knife or the tines of a table fork to give it a more interesting texture when baked.
Set turnover in the middle level of preheated oven and bake for 20 minutes, then check to see if it is browning too much. It bakes 35 to 40 minutes in all and does best at high heat so the pastry will crisp; if it seems to be cooking too fast, turn oven down a little and/or cover top of turnover loosely with foil. It is done when bottom has browned nicely and when juices begin to bubble out of steam holes.
Remove from oven and slide it out onto a rack. Serve hot, warm, or cold. You may wish to accompany the turnover with vanilla ice cream, fresh cream, lightly whipped and sweetened cream, or custard sauce.
Remarks:
Other sizes, other fillings
You can, of course, make turnovers any size and shape you wish, and you can use all sorts of fillings as long as they are not too juicy. Always macerate fresh fruit first with sugar and lemon to force out their excess juices, and a very juicy fruit should first be cooked. Canned fruits or jams bake well in turnovers, as do all sorts of dried nut and fruit mixtures.
Julia Child & Company. Scripts and recipes, show #101: Holiday lunch, 1978. Papers of Julia Child, 1925-1993, MC 644: T-139: Vt-23: Phon 15, 620., Box: 53. Schlesinger Library, Harvard Radcliffe Institute.
Cooked chocolate is heavy in itself, and requires special treatment to avoid a pudding-like soufflé. Therefore, instead of a flour sauce-base, one of cornstarch is used, and 3 egg yolks instead of the 4 which are usual for a soufflé of the following dimensions. Chocolate soufflé also takes 10 to 15 minutes longer to cook than other sweet soufflés.
This recipe will serve 4 people.
A 6-cup soufflé mold
Preheat oven to 375 degrees. Butter the soufflé mold and roll cornstarch in it. Knock out excess starch. Measure out all your ingredients.
2∕3 cup (4 ounces) semi-sweet chocolate bits
2 tablespoons strong coffee
Stir the chocolate and coffee in a small saucepan over hot but not simmering water until the chocolate is melted and smooth. Keep over hot water until ready to use.
A 1-quart saucepan
A wire whip
¼ cup sifted cornstarch
1 cup milk
⅓ cup granulated sugar
Beat the starch and 3 spoonful of the milk in the saucepan until smooth and blended. Beat in the rest of the milk, and the sugar. Stir over moderate heat until the boil is reached. Boil 3 seconds. This will be rather gluey. Off heat, beat in the hot melted chocolate until well blended.
2 tablespoons softened butter
Clean off the sides of the saucepan and divide the butter over the sauce. Allow it to cool until tepid.
5 egg whites
Pinch of salt
¼ teaspoon cream of tartar
1 tablespoon granulated sugar
Beat the egg whites, salt and cream of tartar together until soft peaks are formed. Sprinkle on the sugar and beat until stiff peaks are formed.
A 3-quart mixing bowl
A rubber scraper
3 egg yolks
Scrape the chocolate sauce into the mixing bowl. Beat in the 3 egg yolks, which may be added all at once. Stir in ¼ of the egg whites; delicately fold in the rest. Turn the scuffle mixture into the prepared mold, leaving at least 1-¼ inches between the top of the soufflé and the rim of the mold.
Demonstrations with recipes, 1963-1965. Papers of Julia Child, 1925-1993, MC 644: T-139: Vt-23: Phon 15, 664., Box: 58. Schlesinger Library, Harvard Radcliffe Institute.
Homemade peanut brittle — a simple and inexpensive present that is unbelievably irresistible, and must be hidden away after each serving if you ever want to see any of it for another nibble. Have all equipment and ingredients right at your side because it goes fast and you must be at the ready.
Lightly butter a large tray (1 ½ by 2 feet), or two jelly roll pans, or a pastry marble.
Measure out 3 cups of toasted salted skinned peanuts (the regular, not the dry-roasted kind), ½ teaspoon bicarbonate of soda, and 4 ½ cups of sugar stirred together with 1 ½ cups of water in a heavy 2 ½- to 3-quart saucepan.
Also have ready a cover for the pan, 2 metal spoons, a flexible-blade metal spatula, and a triple thickness of buttered wax paper folded handkerchief size.
Bring the sugar and water to the boil, swirling the pan by its handle to dissolve the sugar. When boiling, remove pan from heat, swirling gently, until liquid is perfectly clear — to make sure sugar does not crystalize later.
Cover the pan and boil over high heat until bubbles thicken, then uncover and boil, swirling pan slowly by its handle (but never ever stirring!) until syrup begins to color lightly — not too much, since it will continue to darken.
At once remove from heat and blend in the with a metal spoon peanuts, turning rapidly with a metal spoon to coat the nuts with caramel. Immediately stir in the bicarbonate of soda — the mixture foams and whitens — the soda changes the caramel texture so it will be brittle but won’t break your teeth.
Scoop it all out onto the oiled surface, spreading it with your spoon. While still warm, continue spreading and thinning, lifting under it with your spatula, pulling with the bowl of a spoon, and, when cool enough, stretching it with your fingers (protected by the wax paper). When cool, in 10 minutes or so, break it up into serving pieces. Store in plastic, then airtight tin box — and hide it!
Remarks:
One Variation: Toasted hazelnuts make a delicious brittle, too. To toast them, which brings out their flavor, spread in a baking pan and set in the middle level of a 350°F oven, tossing and turning them frequently until a light toasty color. Rub in paper towels to remove loose skin, then proceed as for peanut brittle but stir ½ teaspoon of salt into the sugar as you make your caramel.
Another: Grind up small pieces of brittle and use as “streusel,” to scatter over ice creams and custard desserts — this makes a nice gift, too, packed in a pretty screw-topped jar.
Parade typescripts. Christmas, December 1982. Papers of Julia Child, 1925-1993, MC 644: T-139: Vt-23: Phon 15, 912., Box: 83. Schlesinger Library, Harvard Radcliffe Institute.
For about 6 cups baked in an 8-cup mold, serving 12 people at least
Timing: Like a good fruit cake, a plum pudding develops it’s full taste if made at least a week ahead and allowed to cure. It’s then reheated 2 hours before serving.
3 cups (lightly pressed down) crumbs from white homemade type bread (a ½ pound loaf, crust left on)
3 cups (1 pound) mixed black and yellow low raisins and currants, chopped
1 ⅓ cups (½ pound) sugar
½ teaspoon each (more if needed) cinnamon, mace and nutmeg
½ pound (2 sticks) butter, melted
4 large eggs, lightly beaten
A few drops, almond extract
½ cup bitter orange marmalade
½ cup bourbon whiskey or rum
Special equipment:
An 8-cup bowl or uncomplicated mold; a cover for bowl or mold; a roomy kettle with cover; a trivet or steamer basket to hold mold.
Step 1: Pudding mixture
Toss the bread crumbs with the raisins, sugar and spices. Then toss thoroughly with the melted butter before tossing with the rest of the ingredients listed. Taste carefully for seasoning, adding more spices if needed.
Step 2: Steaming — about 6 hours
Pack the pudding into the container, cover with a round of wax paper, and a cover. Set on a trivet or steamer basket in the kettle, and add water to come ⅓ the way up.
Parade typescripts. Christmas, December 1985. Papers of Julia Child, 1925-1993, MC 644: T-139: Vt-23: Phon 15, 948., Box: 84. Schlesinger Library, Harvard Radcliffe Institute.
Ingredients for 8 x 1 ½ inch cake pan
¼ pound softened butter
⅔ cups granulated sugar
3 egg yolks
4 ounces or squares semisweet baking chocolate melted with 2 tablespoon strong coffee or rum
¾ cups sifted cake flour
⅓ cups pulverized almonds
¼ tsp almond extract
3 stiffly beaten egg whites
Cream butter and sugar together then beat in the egg yolks.
Beat in the melted chocolate, then the flour, almonds, and almond extract.
Stir in ⅓ the egg whites, fold in the rest.
Turn into a buttered and floured cake pan and bake in middle level of a preheated 350° oven for about 20 minutes.
Cake should remain slightly moist. Cool 10 minutes, then reverse on a cake rack.
Ice with chocolate and decorate with almonds.
FOR THE ICING: 2 squares melted chocolate creamed with 2 tablespoons unsalted butter, and 10 to 12 whole almonds.
Pasadena Guild of Rosemary Cottage, 1961-1962. Papers of Julia Child, 1925-1993, MC 644: T-139: Vt-23: Phon 15, 662., Box: 57. Schlesinger Library, Harvard Radcliffe Institute.
Mastering the Art of French Cooking. Vol. 2. Original drawings: graphic material. Papers of Julia Child, 1925-1993, MC 644: T-139: Vt-23: Phon 15, 804., Box: 71. Schlesinger Library, Harvard Radcliffe Institute.
Health
The deadly habit we can’t quite kick
Vaughan Rees. Veasey Conway/Harvard Staff Photographer
Alvin Powell
Harvard Staff Writer
December 13, 2024
7 min read
Actions by tobacco companies worry researcher even amid ‘dramatic decrease’ in smoking among young Americans
Smoking has declined in the U.S., but 49.2 millions Americans, about 20 percent, still use tobacco products. And the to
Actions by tobacco companies worry researcher even amid ‘dramatic decrease’ in smoking among young Americans
Smoking has declined in the U.S., but 49.2 millions Americans, about 20 percent, still use tobacco products. And the tobacco wars rage on, with rates rising globally even as they’re falling in many developed countries. Tobacco companies have created new active compounds to replace cooling menthol and mimic addicting nicotine in an end run around state laws seeking to reduce the harm tobacco products do. Those steps forced California in September to pass legislation closing loopholes in laws banning menthol and regulating nicotine. The Gazette spoke with Vaughan Rees, director of the Center for Global Tobacco Control at the Harvard T.H. Chan School of Public Health, about the increasing sophistication of the tobacco battlefield. This interview has been edited for length and clarity.
Tobacco companies have developed new formulations of nicotine and menthol, sparking an argument as to whether the new compounds can be regulated by current laws. How big a loophole is this?
It could be an enormous loophole, and tobacco manufacturers have exploited it in some states. For example, in Massachusetts, when a ban on the use of methylation went into effect, tobacco manufacturers came up with an analog product that functions like menthol, that imparts a cooling sensation, and that was not technically banned under the Massachusetts law. So tobacco manufacturers continued to sell products that looked, tasted, and functioned almost exactly like mentholated cigarettes.
That subverted the intention of the law, which was to prevent consumers from being misled about the health risks of smoking and to prevent young people from starting smoking, in part because of menthol’s cooling sensation.
How big a problem is the substitution of ingredients to circumvent restrictions? Is this a blip and once lawmakers understand the strategy, they can get ahead of it? Or is this potentially opening a new front in the tobacco wars?
Relatively few jurisdictions in the United States have put product standards like this in place. Massachusetts and California are leaders in that area with bans on methylation, and a ban on the use of synthetic nicotine compounds is about to go into effect in California. So tobacco manufacturers haven’t really had to do much, in a wider way, in terms of subverting those laws.
If a federal ban did go into effect, tobacco manufacturers would very likely seek to introduce menthol or nicotine analogs. Better-crafted regulations should eliminate the opportunity for tobacco manufacturers to substitute analog chemicals for menthol or nicotine. But it’s been a long-term theme of tobacco manufacturers to subvert the intention of laws put in place to protect the health of the public.
Another example was the adoption of clean indoor air laws. There was a lot of pushback from tobacco manufacturers or allies of tobacco manufacturers. The owners of hospitality venues argued that they could create smoking sections in pubs or restaurants, for example, that would meet the needs of all of their customers. But the science doesn’t support that. When people are smoking in one part of a room or building, the smoke infiltrates other areas, exposing nonsmokers and workers to secondhand smoke.
In the end, public health and science prevailed, but it took some effort to ensure that public venues were 100 percent smoke-free. Tobacco manufacturers have prevailed in other parts of the world, though. In other countries, laws have been put in place that allowed smoking if portions of the building are open-air.
1%Or less of Massachusetts high school students smoke cigarettes
Are there other significant developments on the tobacco-control scene?
Nicotine is the constituent that causes or promotes addiction, so there’s a rationale for thinking about reducing the nicotine in tobacco products below the level at which those products can be considered addictive. That is something that the FDA has proposed as a potential strategy to reduce harm associated with tobacco products.
The idea is that tobacco manufacturers might one day be required to sell cigarettes and other tobacco products that have such low levels of nicotine that people would never become addicted to them. Those products would still produce smoke that contains carcinogens and other dangerous constituents, but consumers wouldn’t be addicted, and the product couldn’t satisfy anybody’s nicotine dependence.
How far along are plans for this new, low-nicotine cigarette?
The FDA issued a proposed federal rule in 2018. The FDA has regulatory authority for tobacco products and can issue regulations around the way products are designed, formulated, sold, and marketed.
A few years ago, the FDA issued what is called “an advanced notice of proposed rulemaking” to seek public comment and input from stakeholders — which includes public health agencies and tobacco manufacturers — to guide a proposed final rule.
We haven’t seen any further action on that from the FDA, so this is something that could be taken up by states such as California, who have the prerogative to advance those kinds of rules themselves. Regulating product standards is an important strategy, but we have seen less come to fruition in that area.
“Among the lowest-income populations in the United States, we’ve seen little decline in the rate of smoking over the past 30 years.”
Where we’re seeing a lot of impact is around the accessibility of tobacco products: Four years ago, the legal age to purchase tobacco products went from 18 to 21.
Another thing that shouldn’t be overlooked is a dramatic decrease in the use of traditional combusted cigarettes, particularly among youth. Kids who might have smoked 15 or 20 years ago now are vaping instead. That’s not a perfect outcome but presents a lower health risk for those individuals than might have been the case. So we’ve seen a dramatic change in the tobacco landscape with regard to the products used and preferred by young people.
Does that mean the tobacco companies are still making profits with e-cigarettes?
Yes and no. Not all cigarette manufacturers have found a way to pivot to the sale of e-cigarettes — at least in the United States. But the bigger companies, Philip Morris and RJ Reynolds, for example, seem to be increasingly attracted to the idea that nicotine vaping products are the way forward, at least in countries like the United States. In low- and middle-income countries, there’s relatively little interest in moving in that direction. The evidence suggests they’re selling more cigarettes in those countries than they’ve ever sold in the past.
What is the broad trend right now? My understanding is that smoking is down in the U.S.
In the United States and many developed countries, we’re seeing year-over-year declines in the prevalence of smoking, most particularly among younger populations. In Massachusetts, 1 percent or less of high school students smoke cigarettes — that doesn’t include those vaping.
But among the lowest-income populations in the United States, we’ve seen little decline in the rate of smoking over the past 30 years. People who live in federally subsidized housing, for example, smoke at perhaps four times the rate of the general public. People with substance use disorders and mental health disorders smoke at a vastly greater prevalence than the general population. People who’ve been historically oppressed — for example, people of gender and sexual minority — smoke at much greater rates than the general population.
In other parts of the world, it’s very different. We haven’t seen the same impact from tobacco control interventions. There are higher rates of smoking among men in some countries, among both men and women in others.
Optimistically, we may see improvements in many global regions in the near future, as tobacco control initiatives are put in place, as high excise taxes are implemented, as clean indoor air laws are implemented, as restrictions on marketing and advertising go into effect. These all reduce demand for tobacco. So regulations really do matter. These battles need to be fought until the public is no longer being harmed by these products.
Harvard Kennedy School Dean Jeremy Weinstein. Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Seeing is believing
Personal and global events made Jeremy Weinstein want to change the world. As dean of the Kennedy School, he’s found the perfect place to do it.
Alvin Powell
Harvard Staff Writer
December 12, 2024
long read
A series focused on
Personal and global events made Jeremy Weinstein want to change the world. As dean of the Kennedy School, he’s found the perfect place to do it.
Alvin Powell
Harvard Staff Writer
long read
A series focused on the personal side of Harvard research and teaching.
The ruins of apartheid were still smoldering in 1995 when Jeremy Weinstein stepped off a plane in South Africa. A former political prisoner named Nelson Mandela had become president months earlier and the country’s new constitution was still being drafted.
It was a period of hope in a nation whose racist policies had made it an international pariah. But it was also a time of challenge. After a decades-long struggle against white minority rule, once-disenfranchised South Africans had to shift from protest to citizenship, from tearing down an unjust system to building up equality for all.
“There’s this extraordinary moment of change in a country that, like the United States, has race and identity as a critical feature of its makeup and also structural inequality, both in an economic sense and in a political sense,” Weinstein said. “And I thought, ‘Maybe there’s something really important for me to learn from what’s unfolding in South Africa.’”
During his nine months in the country, Weinstein lived with a local family in the township of Gugulethu, took classes at the University of the Western Cape, and nurtured a newhigh school pilot initiative in democracy and public service. The program’s aim was to foster citizenship among youth born as second-class citizens in a divided nation, but who would mature into full participants in South Africa’s new democracy.
“It’s no surprise, given the kind of environment that I was growing up in, that my eyes were open to lots of things around me that I wouldn’t have otherwise seen.”
Jeremy Weinstein
Weinstein, who started as dean of Harvard Kennedy School in July, remembers that seminal moment in one nation’s history as inseparable from his own development as a scholar and a person. In some ways, his upbringing had primed him for his time in South Africa to make a significant impact on his worldview. He had been sensitized to the power of government for both good and ill by a tragedy that destroyed his grandfather’s life. He had been exposed to lively political discussions at the dining room table, where colleagues and graduate students of his academic parents visited regularly. And he had become alert to inequality through the stark differences between his comfortable life in Palo Alto, California, and the struggle for economic security and safety he saw nearby, in East Palo Alto, a town with almost the same name, he observed, but one in which life couldn’t have been more different.
“It’s no surprise, given the kind of environment that I was growing up in, that my eyes were open to lots of things around me that I wouldn’t have otherwise seen,” he said.
‘Case’ tragedy
Weinstein grew up the son of a psychologist mother who was a professor at the University of California, Berkeley, and a psychiatrist father who served as director of student health at Stanford University. His mother’s passion as a researcher was whether teachers’ beliefs about the ability of their students affected the students’ educational outcomes and how to create classrooms where all could thrive. His father’s passion was “The Case.”
Weinstein’s grandfather, Lou Weinstein, was once a prosperous Canadian businessman. In middle age, Lou experienced a series of panic attacks and a bout of anxiety. After consulting with a psychiatrist, was admitted to a psychiatric institution. Over four years, he was hospitalized a total of four times and emerged from his treatments diminished and broken.
“He came back from his hospitalizations a different person, lost his business, lost his identity, lost a lot of basic functioning,” Weinstein said. “My dad was a teenager at the time and became a psychiatrist to figure out what happened to his father.”
In the 1970s, news articles appeared about a CIA program called MKUltra, whose aim was to develop mind-control techniques to be used in interrogation during the Cold War. Among the participating physicians was Donald Ewen Cameron, a psychiatrist who led, at various times, the Canadian Psychiatric Association, the American Psychiatric Association, and the World Psychiatric Association. He was also the doctor who admitted and treated Weinstein’s grandfather.
Cameron’s experiments on unwitting subjects included high doses of PCP and LSD, drug-induced sleep for months on end, and repeated electroshock treatments intended to break down existing behavior patterns. The treatments also included sensory deprivation with the playback of verbal messages to imprint new behavioral triggers for up to 24 hours per day over three months.
“It clicked for my father when he saw a New York Times story and learned what MKUltra was,” Weinstein said. “He realized that this is what, potentially, happened to his dad. It became his life’s work for more than a decade to bring to the public eye what had happened and seek justice for his father.”
“The Case,” as the Weinsteins called it, brought an array of extraordinary people into the family’s orbit, including Joseph Rauh, a noted civil rights lawyer who led Lou’s lawsuit against the CIA.
Evidence was difficult to obtain and the case dragged through the 1980s. Files were classified or had been destroyed, forcing Lou and other plaintiffs in the lawsuit to settle. The justice that might have emerged from a public trial was denied, but one ancillary result was the impact of the ordeal on Weinstein’s home. He grew up in a place where ethics, justice, and politics weren’t theoretical and remote, but rather personal, affecting the people he loved.
“This case was emblematic of what happens when a government loses sight of its obligations to those that it represents, loses sight of the dignity of individuals, loses sight of a commitment to civil rights and civil liberties,” Weinstein said. “It’s painful to think about Guantanamo Bay. It’s painful to think about the wars after 9/11 and the Abu Ghraib prison. It’s painful to think about how these patterns of gross injustice at the hands of government have ways of repeating themselves over time.”
Real-world experience
The summer after enrolling at Swarthmore College, Weinstein headed to Washington, where he worked on the founding of AmeriCorps, a national service program launched by President Bill Clinton to address unmet needs in disadvantaged communities.
While in D.C., Weinstein heard about an opportunity in the new democracy taking root in South Africa. Leaders in the African National Congress were enthusiastic about establishing pilot programs to promote national service. He jumped at the chance, with support from a Swarthmore scholarship.
After he arrived, Weinstein began teaching a course on democracy at a local high school. To enrich the student experience, he arranged public service internships with government organizations and nonprofit partners. Teaching was an energizing experience for Weinstein, but the biggest impact came from his experiences outside the classroom. Weinstein became close with a student and activist named Malala Ndlazi, who was also studying at the University of the Western Cape. Ndlazi wasn’t shy about his belief that the deal ending apartheid was a bad one. It didn’t go far enough in redistributing wealth and resources, he said.
Weinstein and his friend, Malala Ndlazi, during his time in South Africa.
“Almost every night it was me and Malala in the back of the house talking about this moment of extraordinary change,” Weinstein recalled. “I was living in a society that was negotiating the terms of its own constitution — not in the 1700s but in the 1990s — with everything that the democratic project had experienced over hundreds of years about who has voice, who’s included, how you design mechanisms of accountability, how you preserve the rights of individuals but also take advantage of the potential good that government can do, how you think about issues of redistribution. All of these things were being negotiated in real time every day, being contested in the streets, and talked about in the cafes.”
Weinstein threw himself into life in Gugulethu, seeking to build relationships and get to know the community. He ate dinners with his host family and joined a local basketball team. Though Jewish, he attended services with his host family at the Seventh Day Adventists church on Saturday and headed to Catholic Mass with Ndlazi on Sundays.
In September 1995, Weinstein returned to Swarthmore for his junior year. The young person who had been attuned to injustice at home had had his eyes opened to the breadth of the problem globally and the role government might play in remedying it. He studied politics and economics and wrote an honors thesis on Kenya’s struggle for democracy. After graduating, he headed to the Harvard Kennedy School, a place he believed would nurture his dual interests in scholarship and policy.
After his first year in graduate school, Weinstein spent the summer of 1998 working at the National Security Council in Washington, energized by the prospect of peaceful post-Cold War transitions from authoritarian to democratic rule in Africa. Instead, the council’s four-person Africa team faced a summer of unrest: a border war between Ethiopia and Eritrea, an invasion of the Democratic Republic of the Congo by Rwanda and Uganda, embassy bombings in Kenya and Tanzania, and U.S. military strikes in Sudan.
“Africa was very much on the president’s agenda every week, but not because of progress toward democracy and economic growth,” Weinstein said. “Africa was on the agenda because we were dealing with the emergence of conflicts and instability that were associated with this moment of tremendous transition in the region.”
‘Inside Rebellion’
In the summer of 1999, Weinstein returned to Africa. In Zimbabwe, he interviewed people about the country’s military intervention in the DRC. In Zambia, he visited refugee camps on the DRC and Angolanborders.
“Many of these revolutionary movements and even governments purported to speak for citizens, purported to be for things that people wanted,” he said. “Yet tens of thousands of people were fleeing, walking 1,000 kilometers with their most valuable possessions — a sewing machine for one family — on their back. I would go house to house or tent to tent, asking people about why they left to understand what their experience had been of the conflict coming to their community: what the insurgents said about what they were doing, what violence they experienced, and why they made the decision to leave.”
That experience led to his dissertation on rebel violence against civilians. Published in 2007 as a book, “Inside Rebellion: The Politics of Insurgent Violence,” the work explored why some revolutionary movements commit horrific acts of violence againstcivilians and others do not. It was the product of 18 months in the field, traveling alone or with a local graduate student as a research assistant. Living out of a backpack, Weinstein interviewed ordinary people and former fighters. Some of the revolutionaries — such as Uganda’s National Resistance Army — were now leaders of a recognized government. In Mozambique, they were less prominent, settling for peace in an agreement that fell short of the goals for which they’d fought.
Peru was different for a number of reasons. It was the sole location Weinstein visited outside of Africa and the only country whose revolutionaries — the Shining Path — were still active. It was also the only place he encountered trouble.
Weinstein first spent time in Lima, interviewing former rebels in prison and those who had fought them on behalf of the government. From there he traveled to the countryside, where he interviewed ex-fighters and civilians in Ayacucho and illegal cocoa growers in the upper Huallaga Valley, where Shining Path remnants remained active. Late one evening, Weinstein heard a knock on his door.
“It was my research assistant, who had gotten word that the Shining Path was aware of my presence and unhappy with it,” Weinstein said. “We left in the middle of the night.”
The pair took a late bus back to Lima and remained in the capital for several weeks, wrapping up their work.
Weinstein saw a pattern in the numerous accounts he’d collected for “Inside Rebellion.” A key factor in insurgencies, he wrote, is the availability of external resources, such as mining wealth or foreign support. Groups that are able to tap that wealth to build their armies act more coercively toward local populations because they are less dependent on them. Revolutionary groups without those resources are forced to use persuasion rather than coercion.
“It is unusual for someone writing a dissertation to do in-depth fieldwork in three different places, but it’s also one of the things that made the book so convincing,” said Stephen Walt, the Kennedy School’s Robert and Renee Belfer Professor of International Affairs, who was a member of Weinstein’s dissertation committee.
“Indeed, it was necessary to show that the theory could explain not just one type of rebel organization but other types as well. None of these were places where it was easy to do research, and Jeremy deserves a lot of credit for persistence, audacity, and dedication.”
‘Uniquely inspirational’
Weinstein’s first academic job after earning his Ph.D. was as an assistant professor at Stanford, where his work on violence, war, and post-conflict transition continued. He returned several times to Africa as a researcher and became an adviser to the first Obama campaign for the White House. After the 2008 election, he joined the administration as director for democracy and development at the National Security Council. His time in the White House spanned several posts — including chief of staff and then deputy to Ambassador Samantha Power at the U.S. Mission to the United Nations — and numerous international crises, including the Arab Spring, the Ebola epidemic, the Syrian civil war, Russia’s 2014 invasion of Ukraine, and the Iran nuclear deal.
“He proved to be someone who brought this unusual, encyclopedic, academic rigor — the best of academia — and leveraged it to be useful in the meeting, in the moment of crisis, in the strategic review, in the bilateral dialogue,” said Power, a former Harvard faculty member who today is the administrator of the U.S. Agency for International Development.
“Jeremy can see a blank slate and have a vision for what’s to be planted there or what should be built there.”
Samantha Power
“Jeremy has an uncanny ability to see what is not there,” she said. “I might see what is there and it might frustrate me and I’ll try to fix or amend or do away with it. Jeremy can see a blank slate and have a vision for what’s to be planted there or what should be built there. It’s very, very unusual.”
In the years to come, Weinstein, back at Stanford, would refocus on key topics he’d wrestled with while in D.C.
The Syrian Civil War had sent refugees fleeing the country and sparked a crisis that eventually included migrants from Africa, Afghanistan, and elsewhere. With colleagues, Weinstein co-led Stanford’s Immigration Policy Lab, focusing on how best to promote immigrant and refugee integration and the role of national policies in shaping patterns of migration.
With the tech revolution well underway, more undergraduates were entering computer science and related fields, and Weinstein again saw what was not there: instruction in social science, ethics, and public policy that would influence how young computer scientists designed applications, programs, and devices that would influence lives far beyond Silicon Valley. He collaborated with colleagues in philosophy and computer science on teaching and writing projects, and co-authored the 2021 book “System Error: Where Big Tech Went Wrong and How We Can Reboot.”
In addition to his work on immigration and tech, Weinstein co-founded the Stanford Impact Labs, which grew out of his belief that walls between academic disciplines and between researchers and practitioners hinder problem-solving. The initiative brought to the social sciences a research and development approach familiar from engineering and the life sciences, investing in collaborative teams of researchers and practitioners. The organization also launched a fellowship program to help faculty members pursue their ambitions for impact beyond their scholarly contributions. It also created a public service sabbatical to provide faculty the opportunity to embed in nonprofits and in government to better understand how they might contribute to solving major social problems.
Fundamental to Weinstein’s academic achievements is his ability to learn and apply new knowledge, to inspire, and to see across disciplines, traits that will suit him well in his new role, Power said.
“I think that that cross-pollination throughout his career has been what has defined him,” Power said. “Despite the many challenges facing the world right now, Jeremy is a uniquely inspirational person in reminding people of the good that they can do. No matter what the odds are, he finds a way to convince you — you have a chance of making a huge difference.”
Weinstein said that the chance to return to the Kennedy School, an institution at the intersection of scholarship and practice — a place where he can learn, teach, and above all be useful — was irresistible.
“It represents everything I have tried to pursue as a scholar and policymaker,” Weinstein said. “The extraordinary thing about this institution is that it attracts people, whatever role or function they have, who are motivated by problems in the world that they want to solve and believe that universities have an essential role to play.”
Science & Tech
Real reason ACL injury rate is higher for women athletes
Christy DeSmith
Harvard Staff Writer
December 12, 2024
5 min read
Study finds flaw in key sports science metric
Amid news coverage of the 2023 Women’s World Cup, researchers with Harvard’s GenderSci Lab spotted a familiar narrative concerning rampant ACL tears.
There was an immediate attribution of women athl
Real reason ACL injury rate is higher for women athletes
Christy DeSmith
Harvard Staff Writer
5 min read
Study finds flaw in key sports science metric
Amid news coverage of the 2023 Women’s World Cup, researchers with Harvard’s GenderSci Lab spotted a familiar narrative concerning rampant ACL tears.
There was an immediate attribution of women athletes’ disproportionately high injury rates to biological sex differences, remembered Sarah S. Richardson, Aramont Professor of the History of Science and professor of studies of women, gender, and sexuality. “Do women’s hormonal cycles mean that their ligaments are more likely to tear? Does their hip structure mean that their knees are not meant for a certain level of activity?”
In a new study in the British Journal of Sports Medicine, Richardson and her co-authors cast doubt upon explanations that rely solely on sex-linked biology. The researchers specifically homed in on “athlete-exposures,” a metric widely used in the field of sports science — and repeated without question by many journalists covering women’s higher rates of ACL injury. The popular measure embeds bias into the science, the researchers say, because it fails to account for different resources allotted to male and female athletes. They find women may face a greater risk of anterior cruciate ligament (ACL) injury because they play on smaller teams and spend a greater share of time in active competition.
“We knew from previous research that the real story is usually a complex entanglement of social factors with biology,” said Richardson, who founded the GenderSci Lab in 2018. “Our goal was to elevate the consideration that social factors can contribute to these disparities — and to show that it matters quantitatively in the numbers.”
Sports science literature reviewed by the research team included a recent meta-analysis, which arrived at an ACL injury rate 1.7 times higher for female athletes. Most of the 58 studies cited by the meta-analysis calculated athlete-exposures rather simply: the number of athletes on a given team multiplied by total number of games and practices. Exposure was rarely calculated at the individual level. Nor was weight given to time spent in active competition, when injuries are up to 10 times likelier to occur.
Example of the impact of men’s and women’s ice hockey roster size on calculated exposure time, injury rate, and injury risk. This figure represents one men’s and one women’s team participating in one 60-minute ice hockey match, in which six players per team are allowed on the ice at a given time and unlimited substitutions are allowed.
Source: Limitations of athlete-exposures as a construct for comparisons of injury rates by gender/sex: a narrative review, British Journal of Sports Medicine
Men
Women
Roster size-based AEs
28
25
Participant-based AEs
19
17
Player-hours
6
6
Men
Women
Injury rate per 100 roster-based AEs
3.6
4.0
Injury rate per 100 participant-based AEs
5.3
5.9
Injury rate per 100 player-hours
16.7
16.7
Injury risk per team member
0.036
0.040
Injury risk per participant
0.053
0.059
A systematic analysis revealed the folly of this approach. “For every match that a team plays, a women’s team will, on average, train less compared to men,” explained co-author Ann Caroline Danielsen, a Ph.D. candidate studying social epidemiology at the T.H. Chan School of Public Health. “This is significant not only because injuries are more likely to happen during matches. It’s also true that optimal conditioning helps prevent injuries from happening in the first place.”
Underinvestment in women’s sports also means lower rates of participation, with playing time distributed among smaller numbers of athletes. “If you look at one individual woman ice hockey player, for example, her risk of injury is going to be larger than a man who’s playing on a much larger team,” noted co-author Annika Gompers ’18, a former Crimson runner now pursuing her Ph.D. in epidemiology at Emory University. “At the same time, the actual rate of injury per unit of game time is exactly the same.”
Recommendations for more accurately calculating ACL injury risk include careful considerations of structural factors. “We wish, for example, there was more systematic data on inequities in the quality of facilities,” said Gompers, noting the high-profile example of the NCAA’s 2021 March Madness basketball tournament. Also helpful would be better numbers on each player’s access to physical therapists, massage therapists, and coaching staff.
Sarah S. Richardson (left), Annika Gompers, and Ann Caroline Danielsen.
Photo by Dylan Goodman
But the co-authors also call for improving the very metric used to calculate ACL injury rates. That means disaggregating practice time from game time and specifying each player’s training-to-competition ratio. It means gauging athlete-exposures at the individual level. It also means controlling for team size.
The paper is the first in the GenderSci Lab’s Sex in Motion initiative, a new research program promising thorough investigations into how sex-related variables interact with social gendered variables to produce different outcomes in musculoskeletal health. Its fourth co-author is U.K. sports sociologist Sheree Bekker, who led a 2021 paper that called for greater attention to social inequities in approaching ACL injury prevention.
“There’s a deep story here, and a nice case study, of how gender can be built into the very measures that we use in biomedicine,” Richardson said. “If the athlete-exposures construct is obscuring or even effacing those gendered structures, we’re not able to accurately perceive the places for intervention — and individuals are not able to accurately perceive their level of risk.”
View of the scaffolding and damaged Notre-Dame Cathedral after the fire in Paris, April 16, 2019. Christophe Ena/AP Photo
Nation & World
Exact cause of Notre-Dame fire still unclear. But disaster perhaps could’ve been avoided.
Christina Pazzanese
Harvard Staff Writer
December 12, 2024
7 min read
Leadership expert says foreseeable factors all contributed to complex failure. Consistent focus n
Exact cause of Notre-Dame fire still unclear. But disaster perhaps could’ve been avoided.
Christina Pazzanese
Harvard Staff Writer
7 min read
Leadership expert says foreseeable factors all contributed to complex failure. Consistent focus needed on best practices, rules, procedures.
Notre-Dame Cathedral re-opened to worldwide acclaim last weekend after a massive fire ravaged the Parisian landmark in April 2019. French authorities still have not been able to pinpoint an exact cause for the fire, but a new analysis may provide insights into how to avoid such a catastrophe.
The beloved Gothic cathedral, built from wood, limestone, iron, and lead in 1163 along the banks of the Seine, was long the city’s top tourist attraction and the site of many iconic events in French political and literary history. Reconstruction and restoration, from spire to sanctuary, cost an estimated ₵700 million, or about $740 million.
While an official cause has yet to the determined, a new Harvard Business School case study examines the complicated series of mishaps and operational breakdowns that allowed a small roof fire to become a catastrophic blaze. The Gazette spoke to Amy Edmondson, co-author of the case study and Novartis Professor of Leadership and Management at HBS, about what the fire has to teach us about preventing such disasters. Interview has been edited for clarity and length.
The Notre-Dame Cathedral reopened more than five years after a fire brought the entire Gothic masterpiece within minutes of collapsing.
Jeanne Accorsini/SIPA via AP Images.
Why were you interested in the Notre Dame fire for a case study?
Jérôme Barthelemy, a professor at ESSEC Business School in France, reached out to me to ask whether I was interested in co-authoring a case on the fire with him. I said yes, because, for me, this was a quintessential complex failure. I just wrote a book called “Right Kind of Wrong: The Science of Failing Well” in which I identify three kinds of failure — basic, complex and intelligent.
The “right kind of wrong” refers to intelligent failures, which are the undesired results of thoughtful experiments. But complex failures are a fact of life, and they are a phenomenon that when we are at our very best as individuals, but more importantly, as organizations, we can prevent. My research is about what more can we do to prevent tragic events like this, failures like this.
You delineate a number of poor decisions and troubling actions that may have contributed to the fire’s size and destruction. Five years later, why do you think French authorities still have no definitive answer on the cause?
I don’t know for sure. I know only what we could learn from published sources. With that in mind, I think the cause will likely remain elusive, because multiple factors — multiple culprits, if you will — were present. Multiple deviations from best practice are highlighted in the case — everything from workers smoking to a confusing fire code system to a built-in 20-minute delay between a call and the arrival of firefighters in the best of circumstances.
As with all complex failures, contributing factors interacted in complex ways. Identifying a single cause is rarely the best way to think about these kinds of failures. Every one of the small factors, like the workers smoking on the roof or storing electrical equipment near very old wood or doing hot work in the vicinity of the rafters, the way the fire alarm and warning system was set up, and the built-in delay is a potential contributing factor.
I can say confidently that it was devastating to all of those involved, both inside and outside the organization. So, they should be motivated to make changes, but identifying a definitive answer is unlikely.
Given that complex failures are caused by a set of contributing factors, rather than one factor, it can be difficult to motivate change. What I argue in the book is that complex failures are on the rise because of the complexity of our systems. But they are theoretically and practically preventable. And the only way to prevent them is through vigilance — absolute commitment to best practices, a dedication to getting the little things right, all of them.
This is not as expensive or laborious as it might sound. It is about a habit of excellence, driven by the belief that rules and procedures matter, and deviations can escalate in dangerous ways. It’s far more expensive and laborious to clean up a failure like this than to run a tight ship, so to speak.
“Complex failures are on the rise because of the complexity of our systems. But they are theoretically and practically preventable.”
Photo by Evgenia Eliseeva
Could the fire have been avoided or done far less damage if one or two of these particular things had not occurred?
Yes, and that’s characteristic of complex failure. Often, all you need is to remove one or two of these contributing factors, and the failure is prevented. For example, if you didn’t have the fire department showing up 20 minutes after the call, you’d probably catch the fire before it turns into a devastatingly large fire. If you had very strict rules about where the electrical equipment goes, where smoking happens, etc. Take out any one of these factors, and it might have been a different outcome. I can’t tell you which, because we don’t really know.
More than 30 years ago, I was studying DuPont, which conducted multiple high-risk manufacturing activities but nonetheless had an extraordinary safety record, to understand how it worked. And I discovered that people in the company wouldn’t let an executive walk down the stairs without holding the banister; if you did that, you’d get reprimanded. You couldn’t walk around with an open coffee cup. No one at any level would put their key in the ignition of the car until they heard the click of each seatbelt. It was almost second nature.
Now, these seem downright silly. But their belief was: “Watch out for the little stuff.” If you apply that logic to the factory, if you aspire to have everything as close to excellent as possible, you can avoid the tragic perfect storms that cause complex failures.
You study leadership. Was this a failure of leadership?
Yes. By definition, leaders are accountable for the whole. Even if you could say, “Well, I didn’t do it; I didn’t smoke in the rafters.” Well, that is not quite right. As a leader, you did do it. You led in a way that allowed such deviations to occur. Sins of omission are every bit as important as the actual acts that may have contributed to the fire.
What issues do you want students to grapple with from this case study?
Exactly what we’re talking about. First, I want them to understand the difference between a basic failure — with a single, simple cause — and a complex failure, and then to take a close look at the organizational factors, which means managerial factors that allow such failures to happen. And then, I want them to think about what the leader’s role is: what they need to put in place to run an excellent operation. The lesson is that leaders can insist on the discipline and the vigilance needed to prevent complex failures.
Improbably, the building has been carefully restored in record time. Do you think anything else positive can come out of this situation or this tragedy?
Yes. The thing that’s positive that will, I hope, come out of it is that other important landmarks will be less vulnerable. This tragedy was a wake-up call for anyone who has responsibility for an important and fragile landmark, or any public good like a national park or even human safety in a complex operation. The insights do not apply only to ancient cathedrals.
Anytime you are leading or in charge of an important resource, especially anything related to human life, you have a responsibility for being vigilant and thoughtful, and encouraging voice, and for stress-testing your hypotheses rigorously. I think there’s a lot of prevention insight that comes from this case, and because of the emotional nature of that loss, it gets people’s attention and could make a difference in that way.
Illustration by Gary Waters/Ikon Images
Science & Tech
‘Harvard Thinking’: Can people change?
One thing is certain in the new year — we’ll evolve, with or without resolutions. In podcast, experts consider our responsibility.
Samantha Laine Perfas
Harvard Staff Writer
December 11, 2024
long read
Nothing is certain except death and taxes, the saying goes — but there’s another sure thing
One thing is certain in the new year — we’ll evolve, with or without resolutions. In podcast, experts consider our responsibility.
Samantha Laine Perfas
Harvard Staff Writer
long read
Nothing is certain except death and taxes, the saying goes — but there’s another sure thing to add to that list: change.
“The more we resist change, the more we suffer. There’s a phrase I like. It says, ‘Let go or be dragged,’” said Robert Waldinger, a professor of psychiatry at Harvard Medical School and the director of the Harvard Study on Adult Development, one of the longest-running studies on human happiness and well-being.
As humans, we are constantly changing. Sometimes change is pursued intentionally, when we set goals, for example. But change also happens subconsciously, and not always for the better. Richard Weissbourd, a lecturer at the Harvard Graduate School of Education and director of Making Caring Common, said that disillusionment is often underappreciated as a factor in change.
“People can respond to disillusionment by becoming bitter and withdrawing — and cynical,” he said. “They can also respond to disillusionment by developing a more encompassing understanding of reality and thriving.”
Mahzarin Banaji, an experimental psychologist who researches implicit beliefs, said that even our biases can change over time as we experience new circumstances. It’s one reason why it’s important we do not lose agency when it comes to changing ourselves.
In this episode of “Harvard Thinking,” host Samantha Laine Perfas talks with Waldinger, Weissbourd, and Banaji about the value of embracing change.
Transcript
Robert Waldinger: The more we resist change, the more we suffer. There’s a phrase I like. It says, “Let go or be dragged.” There is just constant movement of the universe and all of us as individuals as part of the universe.
Samantha Laine Perfas: You can’t teach an old dog new tricks, goes the saying, and sometimes this feels true. But the idea that people can’t change is a myth. Research shows that people are capable of making dramatic shifts at nearly every stage of life in spite of our habits and biases.
So how much of that change is within our control and how much is at the mercy of our circumstances?
Welcome to “Harvard Thinking,” a podcast where the life of the mind meets everyday life. Today, we’re joined by:
Mahzarin Banaji: Mahzarin Banaji. I’m an experimental psychologist. I live and work in the Department of Psychology at Harvard University.
Laine Perfas: Her work focuses on implicit bias, and she co-wrote the best-seller “Blindspot: Hidden Biases of Good People.” Next:
Waldinger: Bob Waldinger. I’m professor of psychiatry at Harvard Medical School
Laine Perfas: He also directs the Harvard Study on Adult Development, one of the longest-running studies on human happiness and well-being. It tracks the lives of participants over 80 years. And finally:
Richard Weissbourd: Rick Weissbourd. I’m a senior lecturer at the Grad School of Education. I’ve also taught at the Kennedy School of Government for many years.
Laine Perfas: He’s a psychologist and is the director of the Making Caring Common Project at GSE.
And I’m Samantha Laine Perfas, your host, and a writer for The Harvard Gazette. Today, we’ll discuss how, when, and why we change, intentionally and otherwise.
It feels like we live in a culture that is constantly pushing us to do more, be more. Why do we focus on changing ourselves so much?
Waldinger: What’s so striking is that for a long time, developmental scientists focused almost exclusively on children, because children change so dramatically, right before our eyes. And people thought once we got into our 20s, we found work, if we were lucky we found love, and then we were good to go, we were set, and people didn’t change much across adulthood. People began to look more closely and look at their own experience and realize how much change happens psychologically and biologically across the adult lifespan. And so you began to see the kinds of studies of change across adulthood that my study represents that was begun in 1938. But for a long time, adult development was the kind of poor stepchild of developmental science.
Banaji: Psychologists, I think, have been remiss in really studying the two ends of life, right? As Bob said, because we are interested in development for a variety of reasons, we focus on from the day a baby is born and we go through, really, well, the adolescent years because we’re interested in the emotional mind and what happens, the volatility during adolescence, and change and so on. And then we know nothing until again, we get to a much older age where we worry and think about the last decade of life. But every decade we’re changing. We’re entirely different people.
Weissbourd: There’s so many different domains of change, right? And I think we do have a pretty strong belief in our culture that we can become more effective or competent, that we can become happier. There’s a billion-dollar self-help industry out there that is trying to make people feel better.
My work is primarily on moral development, and I don’t think we have strong notions of change in adult life, and that’s a real problem. There’s a notion in many parts of the country that you’re born good or bad, and you’re going to be good or bad your whole life, and I think we’d be a much healthier culture if we saw ourselves as having the capacity to love other people well and more deeply and empathize more deeply. You can have better relationships. And that’s probably the strongest source of happiness we have.
I would just say one other thing, and it’s really partly a question for all of you. But, I think sometimes people don’t think they change because the narrator doesn’t change. Meaning the person, the thing telling the story of their lives doesn’t feel like it changes. And when I ask people about their narrator, do they have the same narrator when they were 8 or 16 or 30 or 50? Most people think the narrator is the same. So if you think of the narrator as the self and the continuity of the self, I think that’s one of the reasons people often think we’re not changing.
Banaji: I’m remembering my good friend Walter Mischel’s theory of personality and this idea that we believe so much that we and other people are largely consistent across different situations. The lovely example that Walter gives is that we meet people in certain roles so we don’t even know the variability of those people. I know the janitor who stops by my office every evening as a janitor, I don’t know him as a father or as a jazz musician or whatever else. These things give us a false sense of continuity. And I think this spills over into feeling change isn’t present or happening when in fact it is. It’s like our skin. I think I’m right that the epidermis, once a month, we have a new skin and even in older people, it’s only a little slower. It’s every two months. But I don’t notice that and that might be an interesting metaphor for us, that something so close to us on our body that we see all the time is going through an entire regeneration every month, but we don’t notice it.
Waldinger: It’s interesting because I think we’re ambivalent about change, that the mind in many ways craves permanence. Rick, as you’re saying, we have this sense of the narrator being the same narrator when I was 8 years old and now when I’m in my 70s, and of course that’s absurd. I’m a Zen practitioner, and the core teachings of Zen and Buddhism is that the self is a fiction. It’s a helpful fiction that we construct to get through the world, but it’s actually fictitious, and constantly changing. But at the same time, as we want permanence, we want something fixed, we say, “Oh, I want to improve.” And so we get on this endless treadmill of self-improvement. So we really have quite a complex relationship with the idea of change, we human beings.
Weissbourd: I’m one of those people who do have a strong sense of self-sameness, that I am the same person when I was 8. Is that not true for you?
Waldinger: When I was 8, I really thought I could be Superman; and I had a cape and I had a Superman outfit, and I ran around and I jumped on and off my bed. I don’t do that anymore, Rick.
Laine Perfas: Maybe you should. Sounds like a great Saturday afternoon.
Banaji: You know, there’s a lovely piece that Robert Sapolsky, the neurobiologist, wrote, in, I think it was in the ’80s. I remember reading it and smiling because I was still in my 20s. And he said something like, “My research assistant colors his hair purple one week and green the other week. He listens to classical music and pop. He eats regular foods and weird foods.” And he said, “Look at me, I’ve had the same shoulder-length ponytail for the last 40 years and I only listen to reggae and so on.” And he concluded that piece by saying if you haven’t changed by a certain age for certain things, you never will. If you haven’t eaten sushi by the age of 22, you never will. If you haven’t had your nose pierced by 17, you never will. So there are certain things that, yes, it feels that way, but maybe there are bigger changes that happen later in life.
Waldinger: One thing that I’ve been impressed by as I study people getting older is that the big change is in our perception of the finiteness of life. That we all know we’re going to die from a pretty young age, but most of us say, “Ah, it’s way in the future” or “I’m going to be the exception here. I won’t die. Everybody else will.” And then what Laura Carstensen’s work shows, and many people’s, is that in about our mid-40s, we really begin to get a more visceral sense of the finiteness of life and that sense of our mortality increases from the mid-40s onward. You can document it pretty precisely and that institutes a whole set of shifts in how we see ourselves, how we see this narrator moving through the world, and how we see our time horizon. There are some things that are going to change just because of the fact of death.
Laine Perfas: It does seem like some people are very open to change, and they’re constantly learning and growing, But then there are other people who are very comfortable with how they are, even if other people maybe think they should change. It makes me wonder, are there some people who are more susceptible to change than others, or more open to it?
Banaji: As with almost any other psychological physical property, yes, there are individual differences and far be it for me to bring up anything political in this moment. But one of the differences between what we consider to be liberal versus conservative, the dictionary definition, is that one group looks forward and wants change and wants to leave behind old ways of doing things. And the other wants tradition and stability. There’s nothing good or bad here. These are both forces. But this is a real difference, I think, in almost every culture. I was born and raised in India, I’ve lived most of my adult life here, and in both cultures, I’ve seen these two big movements pull and push in opposite directions. And I guess at some level, I’d like to think theoretically that it’s good to have a bit of that pull and push.
Waldinger: And as I understand it, there’s some theory and some grounding in empirical data that some of this may be biologically based, that some of us are temperamentally more inclined to resist change. We humans are arrayed on a spectrum, perhaps even biologically, about how much we welcome versus resist change.
Banaji: I can’t help but mention my colleague Jerry Kagan. Jerry’s notion of temperament in early childhood, he had this view that there were certain personality dimensions that are biologically present in early childhood. And I really believe that some of those very much link up to what you’re saying, Bob. So for example, I have a sister who was very shy, anxious, would hold my little frock and hang behind me. And I was so extroverted that at age 6, I wanted to leave home and go off somewhere else. And I feel that this difference in shyness or anxiety or whatever you want to call it, has played a role in our political beliefs. I am open to new experiences. I meet very different people and packed a bag at 21 and with $40 in my pocket took off without knowing anybody in this country. She wouldn’t leave home without thinking for three hours about what she’s going to do. And this does lead to very different outcomes.
Weissbourd: Yeah, there’s some people who are temperamentally very risk-averse and there are other people who are risk junkies.
Laine Perfas: It is worth mentioning, you know, not all change that we experience is desirable or beneficial. You know, if we encounter trauma or negative experiences, if you’ve been in a really bad breakup and the experience leaves you cynical and love-averse. When we’re going through life and we’re experiencing negative experiences that might push us to change ourselves in ways that might be more harmful or cause us to withdraw, how do we wrestle with that tension versus still being open to the world, not really knowing what might happen?
Waldinger: A lot of my clinical work is psychotherapy. That’s my specialty; actually, I still, every day, I see a couple of people in psychotherapy. And what you see is tremendous variability in people’s willingness, interest in, and ability to make internal shifts in how they see the world and how they experience themselves. And some of that, Sam, is based on what you’re describing, which is some people have had negative experiences that seem to have really baked in certain ways of experiencing themselves in the world and certain expectations of the world and of people as being reliable or not reliable, as being intentionally harmful or basically good.
Weissbourd: I would say that most of us experience disillusionment at some point in our lives. My dissertation was on the disillusionment of Vietnam veterans, but I think it’s a very common experience. And I think people can respond to disillusionment by becoming bitter and withdrawing and cynical. They can also respond to disillusionment by developing a more encompassing understanding of reality and thriving, flourishing in the world. We have huge literatures on grief and trauma and depression. We don’t really talk enough about disillusionment, and I think it’s a powerful experience for a lot of people.
Banaji: My colleague Steve Pinker is very fond of pointing out to us something that I think is true, that we may think that we are not changing for the good, but whether you look at women’s rights, whether you look at homicide rates, unemployment, other measures of the economy, happiness — if you take even a 20-year view on most of them, there’s improvement. If you take a 100- or 200-year view, there’s no question that there’s a lot of improvement. Yes, there are pockets where things are getting worse. I’ll put climate in that box and make sure that we don’t forget that. But on many of these things, we are improving. And I come from a country that got independence in ’47, and the remarkable changes I’ve seen over the course of my lifetime in India are just mind-boggling. But our aspirations, I think, for better, which is a very good thing, I think often lead us to not see real progress that has also been made.
Waldinger: And to your point, our cognitive bias that’s built in, our bias to pay more attention to what’s negative and to remember what’s negative longer than what’s positive. When we’re younger, that changes as we get older, but that cognitive bias makes us vulnerable to having this sense that everything’s falling apart and inflamed.
Banaji: I myself showed that bias. When we began to do research on implicit bias, I said to my students, don’t even bother looking for change in it. It’s not going to change. It’s implicit. It’s not controllable. That’s the nature of this beast. We can focus on changing people’s conscious attitudes, but this thing is not going to change, not in my lifetime, and I was completely and utterly wrong on that because even implicit bias, which is not easy to control, we’ve seen something like a 64 percent drop-off in anti-gay bias in a 14-year period. This alone is mind-boggling. How did our culture change so dramatically? How did we go from being so deeply religiously based, all sorts of social pressures, how did grandparents and parents change? All of this happened in a 14-year period, not just on what we say and the rights we’ve given a group of people, but way deep inside of us, our implicit bias has changed.
Weissbourd: Mahzarin, I love this work you’re doing. I’m wondering if you can answer your own question, though. How did this happen?
Banaji: You know, I have many hypotheses, but being an experimentalist makes it really difficult to test these because it doesn’t lend itself to laboratory tests. I think both of you doing the work you’ve done may have better hypotheses, so I would love to hear what they are, but I have a few. The first one is that sexuality had going for it a very positive feature, and that is that sexuality is embedded in all aspects of our society at all levels. There are gay and straight people and everybody in between on the coasts and in the middle of the country, among the rich and the poor, among the educated and the less-educated. I think that’s one of the reasons. I also think that these biases were based in religion, and I think we are becoming a less religious country. So I think perhaps secularism has a small role to play, but I think primarily we are not segregated by sexuality, the way we are on age, the way we are on race. And so I think that just allows for the possibility of change.
Waldinger: One of the things I’ve been impressed by is how powerful stories are. Personal stories, like my son says he’s gay and then, whoa, I’m rethinking a lot of things. But also some of the stories, many people have talked about the influence of media and stories, shows about gay people. And I think that those emotional connections and those very personal stories move us in ways. It’s often when a senator or a congressperson has someone in their family with a mental illness that finally there’s some movement that lessens some of the national policy stigmatization of mental illness. It’s because people have it in their own lives and see it in their own lives in a way.
Laine Perfas: We’ve been talking about the ways that we pursue change or people are open to change. I want to talk a little bit about the people who do not embrace change and who might even fear it.
Banaji: Think about Brexit and also some of what’s going on in this country around immigration and just how much the fear of the outsider has been easy to evoke. There’s certain fears that are just right below the surface. Thinking about groups. It is one of those that I think is a very powerful and easy way to say we don’t want change because it’s so easy to evoke the idea that these people who are not us are going to take our stuff. Somebody just wrote me a week ago and said, do you think there’s a difference between foreign tourists and immigrants? And I said, yes, tourists give us money and we fear that immigrants will take our money. And of course there is a difference. But even within them, there are words that we use. I think this distinction in the word has gone away. But when I was younger, I remember that the word emigre would often be used to refer to white high-status immigrants. And immigrant would be the word to refer to non-white, poorer people coming to our country. So even there, we distinguish to tell ourselves that they come in different kinds, and one is to be feared and the other not.
Waldinger: We also assign these groups who are not us, we assign them the characteristics that we fear are part of us, and we don’t want any part of. So those other people are greedy, those other people are dirty, whatever epithets we apply are often reflections of what we don’t want in ourselves, and we notice glimmers of in ourselves. And so to resist those outsiders, to resist changes that come from the outside, is also saying I’m not going to let this stuff loose.
Weissbourd: I think change also involves grief sometimes and loss, it means a new way of being and foregoing a way of being that’s been very familiar, and the relationships in an old way of being, that you can change in ways that make it so it’s hard to be close to your high school friends. Or you can change in ways that may threaten your romantic relationship.
Laine Perfas: What I was thinking about as I was listening to all of you talk, it’s a fear of the unknown. If I change in some way, I can’t fully predict what that life for me will look like. If it changes, will I even recognize it anymore? Who am I? Do I belong? Is there still a place for me in this new and different world? And I think sometimes that alone can be enough to be like, maybe I’ll just keep doing what I’m doing. It’s a lot to think about.
Banaji: So you’re right, Sam, in bringing this up, because I’ve been worried about a particular issue. You said people for whom their life may not be what they were expecting it to be or had hoped to be, and I think about the group “men” as going through this. Of course, the world still is male-dominated and so on. We just have to look at the disproportionate number of men in power. But I’ve been worried a lot about men being left behind. As somebody who studies bias, I look for it everywhere, especially in places where we would not think to look. And there is something going on in this country. I don’t know how magnified it is elsewhere. But today, 60 percent of college-going people are women. And very soon it will be 65 percent. I think this is terrible for the country. I really believe that we need to hold this to 50/50. It’s not good for the group, but it’s not good for society. In 20 years, I think we will be in a position where we will really regret not having paid attention to this. And it’s not just going to college. There’s just many shifts that are happening for men, that are not getting attention and that I believe should, and it’s a kind of a change, but it’s seemingly having a negative impact on a particular group.
Waldinger: Could you say a little more about that? To hear you say this is really interesting.
Banaji: There’s a book that was written recently, and I wish I were remembering his name, but the book’s name is “Of Boys and Men.”
Laine Perfas: Richard Reeves.
Banaji: Yes, at the Brookings Institute. That book really changed my thinking. I had been feeling this. I had been noticing it because I teach in a concentration, a major, at Harvard that has been slowly turning much more female. And so I began to worry about it because I wondered like, where are the men? Why aren’t they coming to psychology? So when I was the director of undergraduate studies, I started to just collect some back-of-the-envelope data. I said to my colleagues, I’m very concerned about this. I brought it up once in an APA meeting, this is the American Psychological Association group of chairs of psychology departments. And I was slapped down by men and women who said, sorry, we don’t want to worry about this. I was just stunned that we would say such a thing. What can I say? I just feel that there’s now enough evidence that men are saying they’re feeling they’re being left behind. The data are, certainly for college. Now, I know that college is not the be-all and end-all of life and not everybody needs to go to college and so on. But you and I know that going to college changes your life’s trajectory, the way our society is set up currently. It is a very strong path to success. And we’re taking that away from one group of people. To see this happening deserves some attention, in my opinion.
Laine Perfas: I know we’ve been talking at the society level, so I want to bring it a little bit back to the individual. Is it more common for people to change intentionally and purposefully, like they’re pursuing a change in their own life? Or is it more common that we change subconsciously or just simply because of the life experiences that we have?
Waldinger: I would argue it depends on how much pain we’re in. If you have a motivation to change, a conscious motivation, you’re more likely to take steps that are hard and require persistence. But to do that, if things are good, you’re probably not likely to make conscious, deliberate efforts to change because things are good.
Laine Perfas: That’s really interesting. It makes me think about this pursuit of happiness: I still feel unhappy, therefore I’m motivated to constantly keep changing, even though it never actually makes me happier sometimes.
Weissbourd: That’s the kicker, right? That’s the irony, that all the pursuit of happiness often makes you less happy. I certainly agree with Bob about suffering, but I might land differently on the question, just in the sense that I do feel like we’re always evolving, whether we intend to or not. Early adulthood changes you. Parenthood changes you. Midlife often changes people. Aging changes people. So there are inevitable developmental changes that are happening.
Laine Perfas: I was going to ask if we ever get to a point where it’s good to just accept who we are and how we are and to be OK with where we’re at in life.
Weissbourd: I think we have a lifelong responsibility to shield other people from our flaws.
Banaji: I love how you said that.
Waldinger: I also think there’s a distinction between the responsibility to keep trying to be better, to spare other people our worst aspects. And I totally agree with you, Rick. And on the other side, because I see this as a psychiatrist, is this problem of low self-esteem. The Dalai Lama, when he started having more contact with Westerners, said that one of the most striking things for him was that Westerners are much more commonly beset by low self-esteem and harsh self-criticism, much more than the people he encountered in Eastern cultures. Partly because self-esteem is an issue of self-absorption, particularly low self-esteem. And so I think it’s both. I think that we have a responsibility to be better, but that there is also a path to greater self-acceptance, which makes us much more fun to live with when we talk about other people.
Banaji: I never heard the phrase “self-esteem” until I was 24 and arrived in America. And yet there is a positive side to it that I want to point out, and I think this is true of maybe not even Western culture, but the United States. I think Alexis de Tocqueville said something in his book on “Democracy in America” that America was not a better country than other countries, but it had this magnificent ability of looking at its flaws. I feel that this is one of the things that I have loved about this culture. That there is something public about looking at our flaws. And I think it’s the mark of a culture that’s evolving in a very positive direction.
Laine Perfas: Thinking about the coming new year, ’tis the season for New Year’s resolutions and all of these dramatic statements of changes that people are going to make. I’m curious what you all think is beautiful about change and how it can have a healthy place in our lives as we think about changes we might want to make this upcoming year?
Waldinger: Zen perspective? Change is absolutely inevitable. Change is constant. Change is the only constant. And the more we resist change, the more we suffer. There’s a phrase I like, it says, “Let go or be dragged.” That there is just constant movement of the universe and of us as individuals as part of the universe. So I would say, it’s like gravity. It’s just here, it’s with us.
Banaji: But which direction it goes in, the change it’s going to have? That, I think, is for every single one of us to continue to try to shape as best as we see it. And I think in that sense, this year is going to be even more important than other years.
Laine Perfas: Thank you all for joining me for this really wonderful conversation today.
Waldinger: Yeah. What fun.
Laine Perfas: Thanks for listening. To find a transcript of this episode and to listen to all of our other episodes, visit harvard.edu/thinking. This episode was hosted and produced by me, Samantha Laine Perfas. It was edited by Ryan Mulcahy, Simona Covel, and Paul Makishima, with additional editing and production support from Sarah Lamodi. Original music and sound design by Noel Flatt. Produced by Harvard University, copyright 2024.
We ingest equivalent of credit card per week — how worried should we be? In ‘Harvard Thinking,’ experts discuss how to minimize exposure, possible solutions.
Campus & Community
Life stories with a beat you can dance to
Photo by Kevin Grady/Harvard Radcliffe Institute
Anna Lamb
Harvard Staff Writer
December 10, 2024
5 min read
Renowned actress and tap dancer Ayodele Casel premieres her autobiographical musical at A.R.T.
For Ayodele Casel, tap dancing is like a second language — or third, for the woman who grew up both in the Bronx and Pue
Renowned actress and tap dancer Ayodele Casel premieres her autobiographical musical at A.R.T.
For Ayodele Casel, tap dancing is like a second language — or third, for the woman who grew up both in the Bronx and Puerto Rico.
“It is a very improvisational form that is informed by your lived experience … where you grew up, the music you grew up listening to, the music that you respond to, the languages that you speak,” said Casel, 49, a renowned actress and dancer as well as a former Radcliffe fellow. “It’s power to communicate across like barriers of other languages or cultures.”
Casel’s new production, “Diary of a Tap Dancer,” will have its premiere run Dec. 12-Jan. 4 at the American Repertory Theater. The play weaves together Casel’s unique brand of rhythmic tap with song and a narrative that traces her career as well as those of often forgotten female dancers throughout history.
Casel recalls the first time she saw a tap performance. One of her high school teachers showed her video of a performance by Hollywood dancing legend Ginger Rogers alongside her equally famed partner Fred Astaire.
“I just remember tunnel vision, like all of a sudden everything went away. And I was just looking at them float through the screen,” she said. “I thought, ‘Man, that is so cool!’”
Casel was hooked. She began immersing herself in classic movies that featured the form.
But it wasn’t until she was at NYU’s Tisch School of the Arts that she actually tried it. In her sophomore year, she began studying tap under veteran dancer Charles Goddertz. She also befriended Baakari Wilder, a hoofer who would become famous for his starring role in the Tony-nominated musical “Bring in ’da Noise, Bring in ’da Funk.”
As she watched hoofers like Wilder, she found herself increasingly drawn to it. Hoofing is a style of tap developed in African American communities that uses makes greater use of stomps and stamps to create unique and more expressive percussive rhythms.
Casel says she was so taken with hoofing that she took the advice of other dancers and went to a construction site to get a piece of discarded plywood to use as a dancing surface so she could hear her rhythms more distinctly. (Cassel still recalls the hassle of getting her board on the subway to take it home.)
The style still deeply influences Casel, who won the Hoofer Award from the American Tap Dance Foundation in 2017.
In 2019, Casel brought her talents to Cambridge for the first time, becoming the 2019–2020 Frances B. Cashin Fellow at Radcliffe. At Harvard, Casel worked to put together an earlier version of“Diary” — one that was a one-woman history of female tappers.
“The project I submitted was this idea of creating a theatrical work that centered the lives of the Black women tap dancers from the ’30s to the ’50s, whose stories aren’t widely known, and whose stories were almost really completely lost to history,” she said.
“I just felt like as a woman of color in these tap shoes, that it was my responsibility to bring them with me so that as folks get to learn about me, they also inevitably learn about them,” she added.
“I just felt like as a woman of color in these tap shoes, that it was my responsibility to bring them with me so that as folks get to learn about me, they also inevitably learn about them.”
Ayodele Casel
Tomiko Brown-Nagin, dean of the Harvard Radcliffe Institute, echoed the importance of uncovering the legacies of those history has forgotten.
“It was here at Radcliffe that an early version debuted in February 2020,” she said. “More than just a theatrical work, ‘Diary’ contributes to a more complete history of a remarkable American art form by centering the lives of unnamed women within a broader context. I am eager to join so many others in the audience at the A.R.T. to celebrate this history and Ayodele’s considerable talent.”
After seeing Casel’s Radcliffe presentation, A.R.T. Director of Artistic Programs Ryan McKittrick asked her to develop the project for their stage. Since then, it has come to include an ensemble cast of actors and dancers, directed by longtime Casel collaborator Torya Beard.
And although Beard herself has a history as a dancer and choreographer, she wants to be clear that the show’s story about the lives of Casel and the other women tappers lies at the heart of the project.
“‘Diary’ is really rooted in personal narrative, and there is embodied storytelling. [But] when we’re talking about like an Ayodele Casel project, I don’t think it exists without music, and perhaps, at least right now, it doesn’t exist without tap dancing, but this is not a dance concert.”
Nation & World
How the presidency was won, lost
Senior staff from the Harris and Trump campaigns (from left): Molly Ball, Chris LaCivita, Tony Fabrizio, Jen O’Malley Dillon, Julie Chavez Rodriguez, Quentin Fulks, Rob Flaherty, and Molly Murphy.Photos by Niles Singer/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
December 10, 2024
7 min read
Top campaign leaders from both s
Senior staff from the Harris and Trump campaigns (from left): Molly Ball, Chris LaCivita, Tony Fabrizio, Jen O’Malley Dillon, Julie Chavez Rodriguez, Quentin Fulks, Rob Flaherty, and Molly Murphy.
Photos by Niles Singer/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
7 min read
Top campaign leaders from both sides talk about what worked, didn’t at Kennedy School postmortem
Both campaigns agreed the presidential election was unprecedented with only an extremely narrow slice of the electorate up for grabs and the Democrats having to retool strategy and organization for a new candidate in the final stretch. And the thing that may have made the biggest difference was how and where you talked to undecided voters.
Senior staff from the Harris and Trump campaigns gathered at Harvard Kennedy School Friday to explain their thinking at critical junctures during the 2024 election. The postmortem, organized by the Institute of Politics, has been held after every presidential election since 1972.
Jen O’Malley Dillon, who had managed President Joe Biden’s 2020 and 2024 campaigns before taking the helm of Vice President Kamala Harris’ campaign after Biden dropped out in July, acknowledged the considerable difficulty they faced trying to shift a political operation built for one candidate to another with a little more than three months left in the race.
“But when the call came and the president said he was getting out, we really did flip the whole thing without knowing exactly how to do it,” she said. “And then the vice president was so strong out of the gate that I think it made momentum a little bit easier for us to pick up on and gave us a little bit of space to figure out the stuff we hadn’t worked out yet.”
“When the call came and the president said he was getting out, we really did flip the whole thing without knowing exactly how to do it.”
Jen O’Malley Dillon, Biden campaign manager
Jen O’Malley Dillon (left) and Julie Chavez Rodriguez.
The Harris team said they knew from the start that they would be facing significant headwinds because the economy was emerging as a top issue, and voters felt the Biden-Harris administration had not done enough to address the inflation rate.
Beyond that, the Harris campaign leaders walked through other challenges they faced.
They pushed back on the accusations by pundits that they took certain demographic groups, like Black and Latino men, and younger voters, for granted, assuming that Harris’ race and gender would override economic or national security concerns.
“We weren’t running this campaign as an identity politics campaign,” said Quentin Fulks, principal deputy campaign manager for Harris. “We came out of the gate talking to everyone. If you think the economy sucks, it doesn’t get better if there’s a Black candidate.”
At the same time, Fulks said, “It didn’t help that the Trump campaign was obviously targeting these voters and making them feel … whether it be through [an anti-] trans ad, ‘She’s for they/them and Trump is for you,’ they were making her seem as if she was out of touch and out of line with their issues.”
Where the Harris team saw the biggest shift in support was among third-party voters, particularly those who had been dissatisfied with both Biden and Trump. Once Harris got in the race, however, “those voters snapped back very quickly” to the Democratic side, said Harris pollster Molly Murphy. Surprisingly, older voters, a group that Biden had always done well with, ended up being much more supportive of Harris than the campaign expected.
Responding to a common complaint from progressives that Harris’ elevation to the top of the ticket without a primary process was undemocratic, Fulks noted there were just 107 days left after Biden dropped out in which to identify a new candidate, unify the party, and launch an entirely new campaign before Election Day.
To hold an open primary and bypass Harris, Biden’s preferred choice, would have risked alienating Black women, a key Democratic Party voting bloc, and meant fielding a lesser-known candidate with no infrastructure, he said.
“I hear your concern, and I’m not saying that … open primaries are not important, but I also think [the campaign was] such an anomaly [that] it would have almost been virtually impossible to have an open primary of any success that would have put the Democratic Party in a position to be able to defeat Donald Trump,” he said.
Trump did unconventional things like attend mixed martial arts fights to show those voters he understood them and was reaching out.
Chris LaCivita , Trump campaign co-manager
Chris LaCivita (left) and Tony Fabrizio.
The Trump team said that early on one of their biggest challenges involved negative impressions of Project 2025, a collection of conservative policy proposals pushed by the Heritage Foundation and other conservative groups.
Voter concern started to gain traction while Biden was still in the race, especially on TikTok, and it caught the Trump team by surprise. That worry grew to alarm after seeing persuadable voters start to move in response to reports about it and Trump blowing up in anger over news stories tying the document directly back to him, they said.
“Obviously, we recognized that it was an issue, and we needed to kill it quickly,” said Chris LaCivita, co-manager of the Trump campaign.
In fact, Project 2025 was one issue where Democrats had a leg up on the Trump team, but by the time the Harris campaign began to focus on it, noted Tony Fabrizio, a veteran Republican pollster, the race had evolved, and that earlier stickiness and momentum was very hard for Harris to reclaim.
Both sides agreed that communication strategies may have made the biggest difference in 2024. The Republicans proved more effective at crafting and amplifying messages that resonated with 2024’s undecided voters. With so few up for grabs this election, finding and persuading those folks was critical.
Seeing that these voters were part of a larger, growing cohort of Americans who had unplugged from network and cable television, the Trump campaign invested heavily in targeting “streamers” (those who exclusively used streaming services), fans of internet-only programs, and listeners of entertainment podcasts, Fabrizio said.
And it’s why candidate Trump did unconventional things like attend mixed martial arts fights to show those voters he understood them and was reaching out, LaCivita added.
The media asymmetry turned out to be a decisive advantage for Republicans this year, but maybe not for much longer, Fabrizio said.
“Republicans were always more distrustful of what we’ll call the mainstream media than Democrats or independents. And so, what happened is, when the technology became available for alternative sources of information, Republicans were the first ones to flock to it because they weren’t happy. It’s the reason why Fox [News]exploded, it’s the reason why so many online sites are right-of-center sites,” he said.
There are signs the left is also becoming disillusioned with mainstream media after controversies over endorsements at The Washington Post and The LA Times led to the cancellation of more than 250,000 subscriptions, and plummeting ratings at CNN and MSNBC post-election. Younger voters now turn increasingly to TikTok and other online platforms for news, an arena in which the Trump campaign conceded that the Harris team outplayed them. Most importantly, a recent Gallup poll shows only 31 percent of Americans still trust the media.
“That means there’s a chunk of Democrats that don’t trust the media anymore,” Fabrizio said. “As that distrust grows across the partisan spectrum, you’re going to see a greater proliferation of news sources and information sources, both on the right and the left. It’s just going to take a little bit more time for the left to get to where the right has been for several years about the news media.”
Campus & Community
Reckoning with past, striving for better future
Flora Way at the Arnold Arboretum.Niles Singer/Harvard Staff Photographer
Anna Lamb
Harvard Staff Writer
December 10, 2024
5 min read
Street at Arnold Arboretum renamed Flora Way to honor enslaved woman
The roads, walkways, and collections throughout Harvard’s Arnold Arboretum bear the names of influential local
Street at Arnold Arboretum renamed Flora Way to honor enslaved woman
The roads, walkways, and collections throughout Harvard’s Arnold Arboretum bear the names of influential local philanthropists, landowners, and politicians. A new name, Flora, now joins the ranks of those being honored for their roles in shaping the history of the region.
In October, the city of Boston approved changing Bussey Street, named after merchant Benjamin Bussey, to Flora Way in honor of an enslaved woman who lived on an area estate in the 18th century.
Bussey, a sugar, coffee, and cotton merchant in the late 1700s and early 1800s, built much of his wealth through the trans-Atlantic trade of products produced by enslaved workers. He eventually retired from that business and turned his attention to farming.
“He accumulated all these small farm holdings and put it together into what is the Jamaica Plain side of the Arnold Arboretum,” Ned Friedman, director of the Arboretum, said. Friedman is the Faculty Fellow of the Arnold Arboretum and Arnold Professor of Organismic and Evolutionary Biology.
In 1842 Bussey donated to Harvard College his estate, which was combined in 1868 with land donated by New Bedford whaling merchant James Arnold for the creation of the Arboretum.
Bussey is one of several philanthropists identified in the University’s 2022 Harvard & the Legacy of Slavery report as a beneficiary of enslavement. Friedman said the Arboretum has been actively considering how best to acknowledge its past while looking to the future.
“We have a Bussey Hill; we have a Bussey Brook Meadow. We want to honor Benjamin Bussey for his philanthropy, because I feel personally that writing him completely out of history removes the historical context,” said Friedman of Bussey’s complex legacy.
The idea to remove his name from the street, he said, didn’t originate with the Arboretum. Last spring, a group of neighbors across Jamaica Plain and Roslindale came together to suggest the change. They came up with five alternatives to Bussey. The list included Flora and two other enslaved people, Dick Welsh and Cuffe, along with transcendentalist Margaret Fuller, who wrote fondly of the hemlocks and pines on the site, and botanist Shiu-Ying Hu, Ph.D. 1949, a highly respected emeritus senior research fellow at the Arboretum.
“I would have been happy with any of the five names that they suggested,” Friedman said. “I just stepped back and let the community do their business.”
Ultimately, organizers reached a consensus to select Flora — a woman enslaved by William Dudley, the son of Gov. Joseph Dudley.
The Dudley estate was located in current-day Roslindale on Weld Street and included a small commercial farm. Flora was one of four people enslaved on the property, and the only woman.
“Renaming this street to Flora Way makes a powerful statement that Flora mattered.”
Sara Bleich, Harvard & the Legacy of Slavery Initiative
Not much is known about Flora, other than records that detail her purchase price of 40 pounds and the fact that Dudley bought shoes and an apron for her. The only other record of Flora is a probate file showing her sale by Dudley’s estate, again for 40 pounds.
“Flora was connected to what is now the Arnold Arboretum, a place that holds a commitment to public health and accessibility and is intentional about creating equitable access to urban green space,” said Sara Bleich, the University’s inaugural vice provost for special projects in charge of the Harvard & the Legacy of Slavery Initiative at a renaming ceremony at the end of October.
The name change signifies not only Harvard’s acknowledgment of the past, but also a promise to strive for a better future.
“Flora Way is just part of a bigger set of conversations we’re having here about justice, about equity,” Friedman said.
The Arboretum, which is free and open to the public and receives millions of visitors each year, is surrounded by several “environmental justice” communities, where 40 percent or more of the residents are people of color and median incomes fall below city averages.
City-run entrances to the park from those neighborhoods have fallen into disrepair, with gates welded shut and stone walls covered in graffiti. Friedman, and Harvard, have been advocating for their renovation, and in some cases, pledging to support efforts financially.
“Access is really important,” Friedman said. “Because that’s part of what I think matters a great deal about whether people feel welcome.”
Of the nine entrances to the park, five are slated for renovation, including Poplar Gate at the intersection of the new Flora Way and South Street, which is set to be completed within the next month or two.
“Renaming this street to Flora Way makes a powerful statement that Flora mattered,” Bleich said. “Reckoning with past history gives us a fuller view of what came before us, the injustices done that society needs to be held accountable for, and how this should shape our future for the better,” she added.
Since the release of the Legacy of Slavery report, efforts continue across the University to implement recommendations and continue digging into the past. To learn more, a historical tour of 10 stops around Cambridge that explore the University’s connections to slavery is available, and the full report is online.
The Arnold Arboretum is open every day from sunrise to sunset.
James Wood (left) and Laila Lalami.Niles Singer/Harvard Staff Photographer
Arts & Culture
How a ‘guest’ in English language channels ‘outsider’ perspective into fiction
Laila Lalami talks about multilingualism, inspirations of everyday life, and why she starts a story in the middle
Eileen O’Grady
Harvard Staff Writer
December 9, 2024
5 min read
Laila Lalami reached for her phone early
How a ‘guest’ in English language channels ‘outsider’ perspective into fiction
Laila Lalami talks about multilingualism, inspirations of everyday life, and why she starts a story in the middle
Eileen O’Grady
Harvard Staff Writer
5 min read
Laila Lalami reached for her phone early one morning and found a baffling notification. If she were to leave her house right then, it said, she could make it to YogaWorks by 7:30 a.m.
The award-winning novelist did not immediately leave for yoga class. Instead, she spent the day pondering technology and its access to people’s unexpressed thoughts and unrealized actions. The experience, now more than 10 years in the past, left her with the idea for her forthcoming novel.
“I turned to my husband, and I said, ‘Pretty soon, the only privacy we’re going to have is in our dreams,’” Lalami recalled at a recent Writers Speak event hosted by the Mahindra Humanities Center. “Then I thought, ‘What if someday even that boundary starts to become porous? What might happen?’”
Lalami, author of “The Moor’s Account” (2014) and “The Other Americans” (2019), read an excerpt from “The Dream Hotel,” available in March. Moderator James Wood, professor of the practice of literary criticism, also asked her about multilingualism, narrative structure, and finding inspiration in everyday life.
Even after publishing four novels, Lalami — the 2023-2024 Catherine A. and Mary C. Gellert Fellow at Harvard Radcliffe Institute — said she still describes herself as a “guest” in the English language.
The trilingual author grew up speaking both Arabic and French in post-colonial Morocco. Enrolled at a French primary school, her introduction to the written word came via French children’s classics like “Tintin” and “Asterix.” As an English major at Université Mohammed-V in Rabat, Lalami began to resent how early French education had prevented her from developing that initial literary connection to Arabic.
“I developed a dislike of writing in French,” Lalami said. “I felt that the more I did it, the more I felt awkward doing it. It felt to me there was a bizarre sort of colonial gaze that I could not detach from the writing.”
Now working in English, Lalami still feels a sense of estrangement from the language. But she’s able to channel it into her creative process. As a writer, she sometimes imagines her dialogue is taking place in Arabic and she is translating it to English. This was particularly the case with her second novel, “Secret Son” (2009).
“If the story is successful, we forget to question things like what language they are speaking,” Lalami said.
As for narrative structure, Lalami spoke to the tendency of starting her books in the middle of a story, including multiple character perspectives and adding elaborate backstories.
She stumbled upon the approach “organically” with her first novel, “Hope and Other Dangerous Pursuits” (2005), which opens with the capsizing of an inflatable boat carrying four Moroccans across the Strait of Gibraltar. From there, the narrative shifts between each of the characters, detailing their lives before and after the crossing.
“I started writing the story of this character as he’s going through this journey, and the story kept getting longer because I was doing these flashbacks about his life before he got onto that boat,” Lalami explained. “I thought, ‘Well, what happens to this other person that’s sitting next to him?’ So I decided to write a story about them.”
Similarly, “The Other Americans,” her fourth novel and a National Book Award finalist, begins with a car crash and unfolds through nine different first-person accounts. Wood, who is also a staff writer and book critic at The New Yorker, noted the rich details that bring the book’s immigrant characters to life — from the main character, a Moroccan man who names his California business “Aladdin’s Donuts,” to his wife’s confusion over an English sign that reads: “Don’t even think about parking here.”
“If we think of the fiction of immigration, it’s so centrally about varieties of estrangement, right?” Wood said. “It’s about trying to see things with new eyes.”
Lalami said she loves building characters’ backstories right down to the smallest detail. “As somebody who constantly feels as an outsider, I’ve come to realize that it’s very much the outsider-ness that makes me a writer,” she said. “That feeling of being on the outside looking in.”
The outsider perspective is what prompted Lalami to write “The Moor’s Account,” which won the American Book Award and was a finalist for the Pulitzer Prize. The novel is the fictionalized memoir of Estevanico, an enslaved Moroccan on the ill-fated 1528 Narváez expedition to Florida. His name appears only in passing in historical records, inspiring Lalami to reconstruct his backstory before and after the expedition.
During the Q&A session, a student asked Lalami about the steps on her journey to becoming a writer, which included a linguistics Ph.D. program and a stint at a majority-male tech company.
Lalami responded with the same advice she gives to students in MFA programs: Every life experience can become material for fiction. Case in point? Her forthcoming novel features a female main character working at a large tech company.
“That is what helps you become a writer, is that feeling that you’re kind of weird and different from everybody,” Lalami said. “Don’t ever try to be like everybody else. Embrace that weirdness, because that’s what fiction comes out of.”
Campus & Community
Garber installed as Harvard’s 31st president
President Alan Garber.Photos by Stephanie Mitchell/Harvard Staff Photographer
Samantha Laine Perfas
Harvard Staff Writer
December 9, 2024
5 min read
Friends and family, colleagues honor leader who ‘radiates trustworthiness’
Alan Garber was installed as Harvard’s 31st president in a celebration attended by colleagues, Uni
Photos by Stephanie Mitchell/Harvard Staff Photographer
Samantha Laine Perfas
Harvard Staff Writer
5 min read
Friends and family, colleagues honor leader who ‘radiates trustworthiness’
Alan Garber was installed as Harvard’s 31st president in a celebration attended by colleagues, University leaders, and family and friends Saturday at the Harvard Art Museums.
Provost for almost 13 years, Garber was named president in August, after serving as interim leader since January, and has navigated the University through a period of extraordinary challenges and intense scrutiny. Penny Pritzker, senior fellow of the Harvard Corporation, pointed to Garber’s character and experience in praising him for meeting the moment.
The University’s new president “is a person of deep learning, strong values, bedrock integrity, and a fierce commitment to academic excellence,” she said.
Garber, an economist, physician, and health policy scholar, opened his remarks by thanking those in attendance, including his wife and children, for preparing him for his new role. Among those gathered for the ceremony were past Harvard presidents Larry Summers, Drew Faust, Larry Bacow, and Claudine Gay.
“Nothing fortifies quite like a room full of colleagues and dear friends, including my partners in the work and my predecessors in the Holyoke chair,” he said. “This is, in some ways, an inverted lecture. Each of you has taught me important lessons that have guided me to this point.”
He went on to note that the University is facing uncertain times that will require both robust collaboration and an unwavering commitment to integrity and excellence, including in its pursuit of the research and teaching that define its mission. Success will depend in part on embracing risk, he said.
President Garber holding the ceremonial copy of the Harvard Charter with Harvard Corporation Senior Fellow Penny Pritzker (left) and President Emerita Drew Faust.
The Holyoke chair.
President Garber with his wife, Anne Yahanda, and their four children.
“An excessive aversion to risk is a risk in and of itself. We must keep in mind, always, that the mistakes we have made — individually and collectively — may have been plentiful, but we have our long history to celebrate because they have not been fatal. Assuming that this trend continues, our history demands that we plan — boldly — for a very long future. We need to think not only in years and decades, but also in centuries.”
He added: “We forfeit opportunities when we feel as though the University cannot make a move without considering every possible ramification, without fully understanding every possible consequence. In a world that confronts us with challenges and opportunities more frequently than ever before, we will need to move forward with greater alacrity — and to correct course more quickly — than has been our custom.”
Faust, who as president named Garber provost in 2011, recruiting him from Stanford University, described a colleague whose hunger for knowledge is deep and inspiring.
“Alan is interested in everything, curious about everything … he is an intellectual and a practitioner, a thinker and a doer,” she said, nodding to Garber’s experience in medicine, economics, and policy, as well as his love for the arts and humanities. “At a time when trust in institutions generally, and in higher education in particular, has eroded so markedly, Alan radiates trustworthiness.”
William F. Lee, who preceded Pritzker as senior fellow of the Corporation, praised Garber as a leader of “unflappability and humility” who has demonstrated a “fundamental and unwavering determination to advance the best interests of the institution and the broader Harvard community.”
Vivian Y. Hunt, president of the Board of Overseers, said that Garber’s long record of contributions to the University reflects his strengths as a person and a leader.
“Since being formally elected to this presidency this summer, you continued to carry the mantle of leadership with humility, heart, spirit, humor, resilience, and resolve,” Hunt said.
The ceremony included the presentation by Garber’s predecessors of several insignia of the office. Dating to the 17th century, the insignia are traditionally given to each new Harvard president. Faust said that the tradition was not just an opportunity for Garber to pledge his leadership to the community, but also for the community to pledge its support to him.
“It’s a ritual that encompasses all of us, not just the man of honor,” said Faust, the Arthur Kingsley Porter University Professor. “We affirm our support for Alan as he embarks on his presidency, and as he navigates through change and through storm. And we pledge our commitment to doing all we can to ensure that Harvard thrives and the pursuit of veritas prevails in the decades and the centuries to come.”
The impact of that commitment extends far beyond campus, Garber noted, citing the promise of young scientists, pioneering research by recent Nobel laureates, and the service of Harvard veterans.
“The work done at Harvard — the good it does in the world — the good it will do in the world — is wonderfully abundant,” he said.
The ceremony concluded with a benediction by Rabbi William G. Hamilton of Congregation Kehillath Israel and the singing of “Fair Harvard” by Carolyn Y. Hao ’26.
Roberto Lugo during a workshop at the Harvard Ceramic Center.Photos by Stephanie Mitchell/Harvard Staff Photographer
Arts & Culture
Potter gets fired up about helping students find their own gifts
Nikki Rojas
Harvard Staff Writer
December 6, 2024
5 min read
Roberto Lugo says his art creates conversations and ‘that’s where the magic happens’
Ceramicist Roberto Lugo shared his work and
Potter gets fired up about helping students find their own gifts
Nikki Rojas
Harvard Staff Writer
5 min read
Roberto Lugo says his art creates conversations and ‘that’s where the magic happens’
Ceramicist Roberto Lugo shared his work and his best advice with students who dropped by his residency at the Office for the Arts in mid-November.
“I really want to demystify that idea that art is only for people who have those gifts or people who have historically had access to it,” Lugo said in an interview. “For me, art is for everyone. One of the most satisfying parts about art is seeing someone figure out something that they offer that they didn’t think they did.”
The Puerto Rican artist, activist, and educator, whose pots can be found in a growing number of museum collections, worked with more than a dozen undergraduates — most of them women of color — over two days of campus workshops. Each visitor was offered a chance to work on cups or tiles, with Lugo providing generous coaching on everything from perfecting patterns to painting over gray clay. He even opened up about his Philadelphia upbringing and the inspiration he draws from hip-hop.
Aarna Pal-Yadav ’27 during the tile making session.
Underglaze materials line the table.
An overhead camera projection shows Lugo’s tile technique.
“During each workshop with undergraduates, Roberto inspired students to think about their lives and cultural backgrounds as a starting point and an indicator of what makes them unique,” observed Kathy King, director of the Ceramics Program and Visual Arts Initiatives at the OFA. “He then asked them to think about the words that came to mind, creating a visual vocabulary to decorate both cups and tiles with florals, text, and colorful patterns, among other things.”
Institutions including the Museum of Fine Arts, Boston, and the Metropolitan Museum of Art have acquired Lugo’s work in recent years. Tiffany Onyeiwu ’25, who has a concentration in film and visual studies, is a frequent visitor to these spaces and was excited to meet the artist behind some of her favorite pieces.
“It’s been really inspiring to see an artist who has such a significant part of themselves embedded in their work,” said Onyeiwu, who attended both of the workshops Lugo offered. “Contemporary ceramics is becoming more prevalent in American culture, which is something that I’m excited and grateful for.”
Lugo also engaged with the community during a packed public lecture Monday evening at Harvard’s Ed Portal in Allston.
The event opened with performances by Salome Agbaroji ’27 and Elyse Martin-Smith ’25, social studies concentrators who delivered rhymes loaded with clever pottery references. Martin-Smith commemorated the 19th-century work of David Drake, a Black potter who produced a body of vessels while enslaved in South Carolina. Agbaroji, the 2023 National Youth Poet Laureate, captured attention with witty lyrics that cautioned listeners to “just stay out of the kiln” if they can’t “take the heat.”
“I was trying to write something that was very accessible and engaging to honor what pottery is and also honor the hip-hop culture that is so heavily infused in Roberto Lugo’s work,” said Agbaroji.
Lugo with Tiffany Onyeiwu ’25.
Lugo’s presentation covered some of his most popular artwork as well as the people, music, and life events that affected his creative process. While most of Lugo’s art takes inspiration from European and Asian ceramic practices, he is also deeply influenced by Mexican and Peruvian ceramics as well as the textile traditions of Indigenous communities of the Americas.
“One of the specific things that is a challenge for me is that a lot of those communities are still struggling for representation of their own culture,” he said. “Even though I’m inspired by it and some of my work is influenced by it, I quite often stick to formats that are in many ways tropes or familiar visual elements from ceramics history. I try to be very thoughtful with where I borrow from, because I don’t want to replace a culture.”
Another of Lugo’s trademarks is pottery that incorporates portraits, from historical figures such as Frederick Douglass and Martin Luther King Jr. to influential musicians like Biggie Smalls and Erykah Badu. Lugo linked his penchant for portraiture to growing up amid Philadelphia’s great mural scene, with walls featuring people of color.
“Since I didn’t have any art history in school, that was really my perception of what art was,” Lugo said.
More recent works mix traditional methods with broader representative narratives. His “Orange and Black” series, for example, plays on ancient Greek glazed terracotta with modern depictions of city life.
Back at the Ceramics Program studio, Lugo shared a testament of the connective powers of artwork. “As an artist, there’s many different ways to engage with people outside of your own body,” he said. “One of them is through the physical artwork itself. There’s the display of the artwork and how it interacts and engages with people. There’s the educational facet to it, which is giving people the autonomy to make their own artwork. And then there’s the conversations that get created through both education and art-making. For me, that’s where the magic happens.”
Campus & Community
Corporation deepens engagement to advance key priorities
Penny Pritzker. File photo by Stephanie Mitchell/Harvard Staff Photographer
December 6, 2024
long read
Pritzker expresses optimism on efforts to bring community together
Penny Pritzker ’81, senior fellow of the Harvard Corporation, reflected on a year of transition and challenge for the campus community and outlined her pla
Corporation deepens engagement to advance key priorities
Penny Pritzker.
File photo by Stephanie Mitchell/Harvard Staff Photographer
long read
Pritzker expresses optimism on efforts to bring community together
Penny Pritzker ’81, senior fellow of the Harvard Corporation, reflected on a year of transition and challenge for the campus community and outlined her plans for the year ahead in a recent conversation with the Gazette. Pritzker touched on engagement efforts underway at the Corporation, including a new approach to inform the next presidential search, and shared her perspective on ongoing work across the University to advance constructive dialogue and bring the community together.
A leader in business and philanthropy and former U.S. secretary of commerce, Pritzker joined the Harvard Corporation in 2018 and was elected senior fellow in 2022. She also served on Harvard’s Board of Overseers from 2002 to 2008.
This interview has been edited for clarity and length.
We’re coming toward the end of the semester and the end of a difficult year for Harvard and for higher education. How do you reflect on where we are now and how you and the Corporation are thinking about the year ahead?
Let’s not sugarcoat it — it’s been a painful and challenging year for Harvard, and I believe it’s important to acknowledge that even as we’ve begun to build for the future. We’ve faced relentless scrutiny about every aspect of the University, from stakeholders inside and outside the institution. We’re dealing with deep divisions that have emerged in our community due to the war in the Middle East. We are addressing longstanding challenges related to constructive dialogue on our campus and beyond, and we are cognizant of the need to ensure that a wide range of opinions and perspectives can be heard on campus. All of us on the Corporation are grateful to President [Alan] Garber and his team for charting a path through these difficult challenges. I feel optimistic that we are making progress, at the same time as all parts of the University are driving forward remarkable progress and excellence in our teaching and research mission.
Reflecting on the year, what are the lessons that the Corporation is taking on board and how are you planning to respond to those?
There are many lessons. We’ve certainly sought to listen and learn from the community. We have heard the community’s desire for greater transparency. We’ve heard concerns that the Corporation hasn’t engaged with the community sufficiently — and that feedback has informed our approach. We have made an intentional commitment to strengthen engagement and communication. My fellow Corporation members and I have participated in faculty town halls, regular dinners, and small group meetings with faculty members, meetings with the various task forces, and robust engagement with alumni on campus, locally and through virtual events around the country. In the last few weeks I met with the co-chairs of the Presidential Task Forces on Combating Antisemitism and Anti-Israeli Bias and on Combating Anti-Muslim, Anti-Arab, and Anti-Palestinian Bias, and I have been on campus often to meet with faculty, students, administrators, including at events around the Harvard-Yale game.
It is important to ensure we have the pulse of the community and that we are listening intently to the stakeholders in our community so that we understand how to best support Alan and his leadership team in advancing the priorities of the University. We understand that for the well-being of all our students, our community, and our mission, we need to be more open. So, our engagement will continue particularly as we approach discussions around advancing key academic or other priorities, as well as, importantly, the next presidential search. We know in such a dynamic institution that neither the Corporation nor the administration has all the answers. That is why listening, engaging, and taking advice are so critical.
“I feel optimistic that we are making progress, at the same time as all parts of the University are driving forward remarkable progress and excellence in our teaching and research mission.”
On the presidential search, you recently announced a new committee to look at the process moving forward. How is the Corporation thinking differently about the next search?
The new Presidential Search Process Committee will provide advice to the Corporation about best practices for the search for the 32nd president of Harvard, which will begin in late spring of 2026. The work this committee is undertaking, including engagement across our community and externally, will inform how we ultimately undertake that search. Everything from who should be on the search committee, to how faculty and the broader community are engaged. What kind of external support do we need to undertake the search? The mandate for this committee is broad and our interest in advice is sincere.
I will say that our last search was both robust and wide-ranging. We consulted extensively and considered a wide range of candidates before selecting Claudine Gay, who was unanimously selected as the right choice at that time. But we recognize circumstances have changed and we need to think about the search with that in mind and how we best proceed from where we are. We approach this with a lot of humility and a determination to get the right leadership for an institution we all care about so deeply.
Can you say more about the new committee?
In the months ahead, this committee will engage our community to hear thoughts and considerations on how we undertake the next presidential search. They will also continue to gather information on how other institutions conduct these types of searches and look broadly for best practices. The membership is made up of three members of the Corporation — Biddy Martin, Ken Frazier, and Diana Nelson — and three members who will bring perspectives from outside the Corporation: Sylvia Burwell, who is on the Board of Overseers and was president of American University; Patti Saris, who is a former president of the Overseers and federal judge; and Brad Bloom, who has been a successful business leader. All three are alums who have contributed a wide range of other service to the Harvard community.
Alan Garber has been widely praised for his leadership during a tough period. How would you reflect on his presidency so far?
I believe Alan Garber is doing an outstanding job. He has been thoughtful and intentional in advancing our mission and priorities, as well as leading in ways to heal and strengthen our community during a very challenging period. This isn’t just my view, as I also hear this from faculty, alumni, and other leaders. He has helped the community come together, set in motion important initiatives to tackle hate and to encourage and foster open inquiry and constructive dialogue, and all the while helped move forward our incredibly important teaching and research mission.
What would you say has been the hallmark of his leadership to this point?
What we hear from people within Harvard and from many outside is that Alan engages with authenticity and without defensiveness. He is willing to acknowledge that Harvard is not perfect and that of course we have more work to do. I believe Alan is well-positioned to bring the community along with him as we address these challenges.
A great example of this is the work he set in motion on constructive dialogue and open inquiry. In this area, Alan has encouraged deans and faculty to create opportunities for debate and discussion across difference. He and Provost [John] Manning deserve huge credit for that and for leading the work on institutional voice and open inquiry. The report of the working group led by Tomiko Brown-Nagin and Eric Beerbohm brought into sharp focus the problem of students and faculty self-censoring and the implications of that for an academic community.
At the same time, Alan and the entire Corporation are deeply dedicated to ensuring that we center academic excellence in Harvard’s teaching, learning, and research mission. As chief academic officer when he was provost and now as president, Alan firmly believes in the work that happens in classrooms and labs as the core of our mission. So, you see, we can strengthen our community, bridge the divides that exist, and model the very forms of constructive dialogue that are vital to a place like Harvard, while simultaneously celebrating and advancing the teaching, learning, and scholarship that are core to our mission.
“It is important to ensure we have the pulse of the community and that we are listening intently to the stakeholders in our community so that we understand how to best support Alan and his leadership team in advancing the priorities of the University.”
How should the University be considering engaging with the new political landscape in Washington?
While we don’t know precisely what proposals that affect higher education will look like, we believe that engaging with leaders in Washington is critical. Harvard and institutions of higher education across the country must continue to make a strong case for the effective and strong partnership between higher education and the federal government. We cannot take it for granted. This is a partnership that has offered considerable return for the American people in the form of medical discoveries and treatments, insights and innovations that provide personal opportunity for so many in our country, and research and extraordinary innovations that power the U.S. economy as well as improve U.S. competitiveness in critical industries and across the globe.
Fundamentally, in this time of great change I believe that higher education can do more to expand opportunity for many, whether that’s economically or from a well-being standpoint.
Alan has been in Washington on six occasions in the last year, and I know he is planning to continue his advocacy for this partnership in research funding, financial aid, and other areas. This is work that has my support as well as that of all the other fellows.
It’s been widely discussed that the portrayal of Harvard from some outside the University bears little resemblance to the day-to-day experience of those living, working, studying, and researching within the community. Do you feel that some things get lost in the noisy swirl around higher education right now?
Yes, it is frankly striking to be on campus and to speak with hundreds of students, faculty, and others over the course of the last year. The focus here remains — as it has always been — on the pursuit of excellence on every front. Supporting that campus environment is something the fellows take incredibly seriously, and several times throughout this semester — so far — we’ve been reminded of what is possible here at Harvard.
This includes the eight Harvard College students selected as Rhodes Scholars in recent weeks. Harvard Medical School Professor Gary Ruvkun was named a Nobel laureate. Earlier this semester, we had the announcement of a new AI-driven cancer diagnostics tool developed by HMS researchers. Just last month, we saw the launch of the Lavine Learning Lab at the A.R.T., with support from Jonathan and Jeannie Lavine, which will strengthen engagement between public high schools and the A.R.T.’s groundbreaking theatrical programming.
These are all exciting developments and recognitions. They are also powerful examples of how our community provides the opportunity for our students and faculty to pursue excellence, and along the way impact lives well beyond the boundaries of our campus.
Advancing excellence is where President Garber is focused and the Corporation is fully supportive. Together, we are listening and learning. The University is on the right track and making progress under Alan’s leadership. Of course, we will face hurdles and challenges. But let’s step back. Harvard is a special place and a special community. All of us are committed to the mission of excellence in teaching, learning, and research, as well as to the goal of ensuring the well-being of all members of our community — students, faculty, staff, and more.
Campus & Community
Why I changed my mind
Harvard students describe a time they saw the world in a new light
Danny Laughary '25
Harvard Correspondent
December 5, 2024
8 min read
‘I never once thought that I didn’t want to believe in something’
Dara Omoloja ’26
Dara Omoloja Stephanie Mitchell/Harvard Staff Photographer
I’ve had a lot of conversations with my peers at dinner
Harvard students describe a time they saw the world in a new light
Danny Laughary '25
Harvard Correspondent
8 min read
‘I never once thought that I didn’t want to believe in something’
Dara Omoloja ’26
Dara Omoloja
Stephanie Mitchell/Harvard Staff Photographer
I’ve had a lot of conversations with my peers at dinner and in class about religion. I grew up very Christian, but when I came to Harvard, I started questioning a lot of the beliefs I grew up with: Maybe what I believed to be true wasn’t exactly what I thought it was.
When I look at Christianity now, as much as I see a message of love, I also see a lot of issues with the way that it’s practiced. I wanted to become more open, learning more about my friends’ religions and also getting involved with multiple different populations. There are so many people with so many different mindsets and beliefs here and so I felt like it was the best place to explore.
At one point, I was bordering on being agnostic or spiritual, but one thing that stuck with me is the fact that I never once thought that I didn’t want to believe in something. Even after I spoke to so many people, I find importance in religion, not just because it’s something you should follow, but because it’s just nice to have faith in something even if it might not be real. I think it’s an important comfort for some people that they might not be able to find it anywhere else.
After this class, I washed my hands of germophobia
Ricardo Fernandes Garcia ’27
Ricardo Fernandes Garcia.
Stephanie Mitchell/Harvard Staff Photographer
I took a class called “Microbial Symbioses,” and I’m not a STEM person but that class really expanded my mind. We saw the different ways we interact with bacteria or microorganisms, and the way society tends to see microbes as enemies. We tend to be germophobic and sanitized. We tend to see them as related to plague and illness. But this class showed that we live because of microbes. Everything that is living interacts with microbiology. Even in coral reefs, the microbes allow the coral to survive.
One of the chapters we read talked about how hospitals usually keep their windows shut. But because of the way microbes flow in the air, it is better to have open windows in hospitals. There have been studies that show having open windows in hospitals allows patients to recover faster. We tend to see health as correlated with sanitation. We don’t want to get infected. But this class was reframing it as having people infected with the correct microbes, microbes that are beneficial, as opposed to not being infected. It’s an interesting way of reshaping medicine.
A dining hall chat led me on a listening and tasting tour of 4 countries
Joseph Foo ’26
Joseph Foo.
Photo by Jodi Hilton
Last summer I was going to do research on noodles. It was the most bizarre and random topic I could think of. I was really confused when I was writing my proposal. There were so many theories, so many methodologies, so many different ways of doing it. There was so much information out there. HOLLIS was swarming me with texts.
So I was going to Friday dinner at Pfoho, and I happened to meet a Dining Services worker whom I see every week. It just so happened that day they were serving a cuisine that was native to her. And she was talking to me about the food, where it came from, and how happy she was to see her own local traditions being represented. She gave me a whole backstory about her upbringing, her recipes, her life experiences. I was amazed by her passion and the joy she had in talking about food. And then that got me thinking: “What if I throw away all that theory for a second, and I just steep myself in good old ethnography? Forget the theory, forget all these big academic ideas. Listen to the stories, learn from them, collect them, make sense of them later.” That’s what I did. So for the past three months, I’ve been doing noodle research in Japan, Mongolia, Korea, and Greece. I went through a typhoon, I went to the mountains, got lost on a bus, I went through all sorts of different things. It was amazing, an absolute blast. And it all started with me getting answers to a question I didn’t know I had.
You expect the best conversations to be in class, to be with your professors, to be with your teaching fellows, to be with your classmates. And that’s true, you know. They give you wonderful conversations. But sometimes, it’s the places you least expect that you get the most out of. To that end, I always say that conversation is about two things: It’s about trust, and it’s about humility. You need to be humble enough to learn from anyone and everyone you meet. Also, from that trust, from that bond between people that gets you talking not just from the mind but from the heart. Get them to share what really means something to them. That’s something that really changed my life this summer.
I was an introvert until I had to live with 4 strangers
Juhee Kim ’28
Juhee Kim.
Photo by Jodi Hilton
During the summer, when we first got our rooming assignments, I found I was going to be in a room with four different girls. This is a hallway situation, so there’s one shared bathroom. We had three singles and one double. All of us obviously wanted a single, including myself. And because I’m very introverted, I didn’t know how to say it to them. So I sucked it up. Me and this other girl were like, “You know what? Let’s stop fighting. We’ll be in the double together.” When I got here, I wasn’t in the best mood because of this entire situation. But I ended up loving all of them. I love the hallway situation. We actually opened our suite doors so that we would have one long suite together. And I’m so close with all of them. I don’t know where my introvertedness went to — it’s definitely still there — but I’m definitely so much more extroverted than I was in high school. I love my roommate, and I really like everybody in the hallway. I don’t know how I got here. I’m so extroverted now, and I’m so social.
Even if you’re in a room of four girls you’ve never met in your entire life — one is international, we’re from everywhere all over the country — even if it’s completely random, there’s so many different ways to get along and connect with them, even if you’re so introverted like I was in high school. I’ve loved my experience at Harvard so far, and I’m sure I’ll enjoy it for my next four years. And I’m actually planning on blocking with them. I’m not really the type to say my thoughts very much. Even if I have opinions, I just keep it to myself so that there’s no conflicts. But my roommates are very straightforward. They will come to me and be like, “No. Speak your truths. Say your things. Don’t keep it to yourself.” That made me a lot more open with all of them, and that definitely improved our relationship.
‘When I was growing up, the idea of studying gender and race seemed like a waste of time’
Michelle Chang ’26
Michelle Chang.
Stephanie Mitchell/Harvard Staff Photographer
Last year, I took a class, “Race, Gender, and Performance.” Growing up in a very traditional Asian household, the ideas of sexual orientation and gender are not really talked about. I started from knowing what a man is and what a woman is. I didn’t really understand the psychological aspects of gender. After this class, my perspective changed, in the sense that I’d thought that gender was really a biological factor, but I realized it’s something that changes between different individuals. Despite the fact there are psychological differences between people, there’s actually a very logical explanation for a lot of things. That’s what I learned through the different gender theories in the class. When I was growing up, the idea of studying gender and race seemed like a waste of time, especially because my parents valued hard technical classes like STEM, math, physics, etc. Learning gender theory helped me understand individuals who don’t relate to heterosexual norms.
Best advice I’ve gotten here: Put passion first, money will follow
Trevor Sardis ’28
Trevor Sardis.
Stephanie Mitchell/Harvard Staff Photographer
Coming in, I was looking to do a major where I made the most money. I talked to a lacrosse teammate, and he told me I should focus on what I’m interested in. I should enjoy my time here as much as I can. The major doesn’t matter. You could go find a job where you’ll make money, and with a major that you’re interested in, you can find a job that you’re interested in as well. That was probably the best piece of advice I’ve gotten here. That made me change the way I look at how I’ll do school over the next few years.
— As told to Danny Laughary ’25, Harvard Correspondent
Health
Why do gliomas tend to recur in the brain?
Researchers revealed which neurons in a mouse brain, shown in red, connect to a human glioma, shown in green.Image: Annie Hsieh
Stephanie Dutchen
HMS Communications
December 5, 2024
6 min read
First look at the interplay between neurons and tumors sheds light on formation, spread
Every week, Harvard Medical School neuro-oncologist Annie H
Researchers revealed which neurons in a mouse brain, shown in red, connect to a human glioma, shown in green.
Image: Annie Hsieh
Stephanie Dutchen
HMS Communications
6 min read
First look at the interplay between neurons and tumors sheds light on formation, spread
Every week, Harvard Medical School neuro-oncologist Annie Hsieh treats patients with gliomas — the most common type of brain cancer, including the deadliest, glioblastoma.
After Hsieh’s neurosurgeon colleagues remove a glioma surgically, it often looks like none of the cancer is left behind, she says. Radiation and other treatments may follow. Yet gliomas tend to come back, not just at the original site but in distant parts of the brain, threatening neurological harm and, in some cases, death.
What happens in the brain to encourage these tumors to regrow there, while only rarely appearing in other parts of the body? The question has stumped scientists for decades and made gliomas one of the hardest-to-treat cancers. It’s also a mystery that physician-scientist Hsieh has long wanted to solve.
Now, she and HMS collaborators have filled in a piece of the puzzle by providing the first look at the types of neurons in the brain that connect to gliomas.
The team’s findings were reported Wednesday in PNAS.
Profiling the identities and properties of such glioma-innervating neurons in mice provides new insights into what drives these cancers’ formation and spread in the brain. The findings can also help researchers devise new treatment strategies to stop these tumors from coming back.
“This is a first step that provides a visual explanation for why the tumors can be everywhere in the brain,” said Hsieh, first author of the study and HMS instructor in neurology at Mass General Hospital. “We can now see where the connected neurons originate, study how they integrate with gliomas, and look for opportunities to interrupt growth.”
“It’s fascinating how the neural network functions and how these super-scary tumors integrate with and infiltrate the entire nervous system.”
Annie Hsieh, neuro-oncologist
The study overcomes a long-standing obstacle to visualizing and analyzing the neurons that link with gliomas and demonstrates a way to advance the study of interactions between tumors and the nervous system more broadly.
Hsieh conducted the work when she was a research fellow in neurobiology in the lab of Bernardo Sabatini and in cell biology in the lab of Marcia Haigis in the Blavatnik Institute at HMS. Haigis and Sabatini are co-senior authors of the study.
How gliomas hack the network
Gliomas arise from glia, cells that perform essential functions in sculpting and maintaining neural circuits. Scientists already knew that neurons form synapses onto glioma cells, but they couldn’t see where the other ends of those neurons (the cell bodies) are in the brain. That obscured the neurons’ identities.
Hsieh and team successfully traced the glioma-innervating neurons back to their sources using a rabies virus engineered to infect only specific cells of interest and to light up those cells when it gets in. The virus travels from the tumor cell back through the neuron that connects to it.
The researchers injected human glioma cells into the brains of mice and waited for neurons to connect with the tumors. They then applied the rabies virus to light up cells of interest. Soon, they had a picture illuminating the mouse brains showing all the glowing neurons that led to the glioma.
The maps revealed that the gliomas hook into existing patterns of neuronal wiring.
“The wires are already there; the gliomas just connect to them,” Hsieh said. “They hijack what’s already in place rather than forming their own arbitrary connections.”
And those neurons originate from across the brain, the researchers observed.
“They come all the way from the interior part of brain to go to the tumor,” Hsieh said. “It’s fascinating how the neural network functions and how these super-scary tumors integrate with and infiltrate the entire nervous system.”
Unmasking neurons’ secret identities
The team found that most of the glioma-innervating neurons extending from the far reaches of the brain are the type that makes glutamate, a major brain chemical that excites neurons. This finding aligns with previous observations that neuronal excitation stimulates glioma growth, and that neuron-glioma communication involves glutamate.
Subsets of the far-reaching glioma-innervating neurons, though, showed signs that they make both glutamate and another chemical called GABA, which inhibits neuronal activity. In some brain areas, glioma-innervating neurons from near the tumor site appeared to be largely GABAergic.
The results suggest that neurons that interact with glioma cells are more diverse than currently appreciated. The implications of this for tumor growth and spread are not yet known.
“We see that the tumor is connected to everywhere. Whether these connections provide a path for them to go everywhere is something we need to study,” Hsieh said.
The team probed the electrical properties of the glioma-innervating neurons and found certain differences between them and similar neurons in brains without glioma. Such variations between normal and glioma-innervating neurons or between neuron-neuron and neuron-glioma interactions offer valuable clues to researchers like Hsieh, who seek ways to intervene in cancerous processes while preserving normal function.
The need to develop glioma treatments is urgent, Hsieh said. Researchers have tried to treat gliomas with drugs that work for other types of cancers, but most of them have failed, she noted.
“By unraveling the drivers of glioma-neuron interactions and identifying unique mechanisms, we can explore strategies to interrupt them, potentially stopping the tumors in their tracks and preventing their return,” Hsieh said.
Although she knows it will be many years before discoveries made in the lab translate into therapies for her patients with glioma and others around the world, Hsieh remains optimistic that these latest insights can help move the field forward.
“It’s not close to the clinic yet,” she said, “but it’s one inch forward.”
Additional authors include Sanika Ganesh, Tomasz Kula, Madiha Irshad, Emily A. Ferenczi, Wengang Wang, Yi-Ching Chen, Song-Hua Hu, Zongyu Li, and Shakchhi Joshi.
This work was supported the National Institutes of Health (including National Cancer Institute award K12CA090354), Howard Hughes r Institute, Lubin Family Foundation Scholar Award, American Academy of Neurology, Burroughs Wellcome Fund, Ludwig Center at HMS, and Glenn Foundation for Medical Research. Confocal images were acquired at the Core for Imaging Technology & Education at HMS, and fluorescence in situ hybridization was performed by the Neurobiology Imaging Facility at HMS.
Haigis received research funding from Agilent Technologies and ReFuel Bio; serves on the scientific advisory boards of Alixia, Minovia Therapeutics, and MitoQ; is on the editorial boards of Cell Metabolism and Molecular Cell; and is a consultant and founder of ReFuel Bio.
Health
Probe the gut, protect the brain?
Illustrations by Judy Blomquist/Harvard Staff
Alvin Powell
Harvard Staff Writer
December 5, 2024
long read
In fight against Parkinson’s and other disorders, two-way connection may someday lead to a breakthrough
For Jo Keefe, the trembling hands and trouble walking were bad, but it was the nausea that was truly debilitating.
“For two or three ye
In fight against Parkinson’s and other disorders, two-way connection may someday lead to a breakthrough
For Jo Keefe, the trembling hands and trouble walking were bad, but it was the nausea that was truly debilitating.
“For two or three years, I was having nausea for several hours every day,” said Keefe, a retired lawyer living in New Hampshire who suffers from Parkinson’s disease. “I’d wake up in the morning feeling sick and I couldn’t make any plans at all. Fortunately, I was retired, but I wasn’t planning on this for my retirement.”
Parkinson’s is a neurodegenerative disorder affecting cells that control movement. Patients and the doctors who treat them have long known that severe gastrointestinal issues — nausea, abdominal pain, diarrhea, constipation — are a feature of the condition, in some cases preceding neurological dysfunction by decades. But in recent years research around the disease has started to point to a connection that is more than incidental. The gut, experts say, may be where Parkinson’s starts.
Such a model, if supported by future research, would revolutionize our understanding of the nation’s second most common neurodegenerative disorder, opening a path for specialists to help patients like Keefe before neurological symptoms appear. It would also have the potential to inform treatment of other neurodegenerative disorders, including some of the most devastating in human health.
“What if you were able to get your screening colonoscopy and be told there’s a sign that you’ll progress to Parkinson’s unless we intervene now. And wouldn’t it be wonderful if we had a way to intervene now?”
Trisha Pasricha, specialist in neurogastroenterology and director of clinical research at Beth Israel’s Institute for Gut-Brain Research
Trisha Pasricha.
Niles Singer/Harvard Staff Photographer
“Everyone’s goal is to find an early biomarker for Parkinson’s and our hope is that we can find one in the gut,” said Trisha Pasricha, a specialist in neurogastroenterology and director of clinical research at Beth Israel Deaconess Medical Center’s Institute for Gut-Brain Research. “What if you were able to get your screening colonoscopy and be told there’s a sign that you’ll progress to Parkinson’s unless we intervene now? And wouldn’t it be wonderful if we had a way to intervene now? There are many steps that need to happen, but that’s the goal.”
Central to Pasricha’s vision is the gut’s enteric nervous system, which contains as many neurons as the spinal cord and presides over digestive processes that function as the body’s intake department: proteins, carbohydrates, alcohol, drugs, fiber, agricultural pesticides, hormones given to livestock, chemicals used in food processing, bacteria, viruses, and on and on. The system processes signals about what we’ve consumed and how to respond: throw it back up or move it along; speed it up or slow it down.
Also key: a focus on the two-way nature of the gut-brain connection. Stress caused by the perception of potential danger can cause digestive ills, for example, while signals from the gut’s own nervous system, the enteric nervous system, can spur the brain into mobilizing the body via hunger, cravings, nausea, and pain.
“The enteric nervous system is this large network that runs throughout the gut,” Pasricha said. “It’s constantly signaling, influencing our mood, our wants, our needs. Some of the earliest animals had an enteric nervous system well before anyone developed a brain, well before anyone developed a central nervous system, because we all had to eat. It’s like the OG of our bodies.”
The gut-brain connection goes both ways. Stress caused by the perception of danger can cause digestive ills, for example, while signals from the gut’s enteric nervous system can spur the brain into mobilizing the body via hunger, nausea, and pain.
The gut is also home to the microbiome, a symbiotic community of thousands of species of bacteria and other microbes whose chemical byproducts promote health by protecting against pathogens and regulating immunity. Except, that is, when the balance fails, and symbiosis turns to “dysbiosis,” in which the chemicals released by our microbial companions interfere with healthful processes. Researchers have only scratched the surface of the microbiome’s complexity, but they’ve identified shifts in the gut microbial community — some bacteria populations rise and others fall — not only in Parkinson’s but in Alzheimer’s disease, multiple sclerosis, and amyotrophic lateral sclerosis.
“Parkinson’s disease is very well known and that galvanizes a lot of research,” Pasricha said. “What we often find in science is that when we understand mechanisms behind one disease, it teaches us lessons that we can apply to the other diseases too.”
Theories of the case
There is some variation in Parkinson’s disease, which affects nearly 1 million Americans, but the most common form of the condition, sporadic Parkinson’s, is believed to stem from a complex interaction of environmental and genetic factors.
The disease develops over decades and is caused by a misfolded protein — alpha-synuclein — accumulating in dopaminergic neurons, which play a key role in regulating movement, cognition, and emotion. This process leads to the disease’s characteristic tremors, followed by slowed movements, altered gait, and impaired balance. The impact on neck and facial muscles slurs speech. Patients can experience difficulty swallowing, leading, in later stages, to the need for a feeding tube. The degeneration can spread to other types of neurons and, in some cases, contribute to dementia.
In 2016, researchers examined samples of gut tissue taken from Parkinson’s patients before they developed symptoms. They found alpha-synuclein present in the gut as early as two decades before it appeared in the brain. Additional studies have offered clues to how the protein might travel to the brain, showing that peptic ulcer patients who underwent vagotomies — severance of the main nerve connecting the gut and the brain — experienced significantly lower incidence of Parkinson’s disease.
These findings have led some scientists to embrace the idea that alpha-synuclein appears first in the gut in some forms of Parkinson’s. There, the protein — or changes associated with it — may create disturbances in the enteric nervous system, causing severe constipation, gastroparesis, and other hallmark Parkinson’s gut symptoms. It then moves up the vagus nerve to the central nervous system, where it begins the assault that leads to neurodegeneration.
Some researchers think alpha-synuclein, a protein associated with Parkinson’s, first appears in the gut and then travels the vagus nerve to the central nervous system, leading to neurodegeneration.
In September, Pasricha and colleagues added to that emerging picture, linking damage to the mucosa that lines the upper small intestine to Parkinson’s disease. The study, published in the Journal of the American Medical Association, found that among more than 9,000 patients with no signs of Parkinson’s when they were examined, those with mucosal damage experienced a dramatically increased risk — 76 percent — of later developing the disease.
Subhash Kulkarni, an assistant professor at Harvard Medical School and co-author on the paper, cautioned that while the results are intriguing, much work remains. Scientists still don’t know for sure what alpha-synuclein does in the gut, he noted, and the protein has also been found in the skin and salivary glands.
“These are initial forays,” Kulkarni said. “The relevance of these proteins in the gut to Parkinson’s is still not well understood.”
Beyond Parkinson’s
Laura Cox arrived at Brigham and Women’s in 2019 for postdoctoral studies on the microbiome, focusing on multiple sclerosis, a neurodegenerative condition in which the immune system attacks the myelin insulation that sheathes nerve cells. She worked in the lab of Howard Weiner, the Robert L. Kroc Professor of Neurology, who kept a plaque on his desk that read “Cure as many diseases as possible.” She took that admonition to heart.
“We said, ‘If we’re going to do the microbiome and MS, we’re going to work with our neighbors across the hall,’” said Cox, today an assistant professor of neurology at Harvard Medical School and the Brigham’s Ann Romney Center for Neurologic Diseases. “A really important thing that’s emerging is that there is clear evidence that the gut microbiome can influence neurologic disease.”
In addition to MS, Cox’s lab works on Parkinson’s, Alzheimer’s, and ALS, trying to decipher how gut microbes influence diseases that a few decades ago were thought to be confined to the brain and central nervous system. What she and other experts have found is that “dysbiosis” — shifts in the microbiome favoring one species of bacteria over another — occurs in each condition. And some of the same names keep popping up: Bacteroidetes, Akkermansia, Blautia, and Prevotella, among others.
Neurologist Laura Cox works on MS, Parkinson’s, Alzheimer’s, and amyotrophic lateral sclerosis.
Part of her aim is to illuminate how these conditions might be affected by gut microbes.
One area of intense focus is “dysbiosis,” shifts in the microbiome favoring one species of bacteria over another, and some of the same names keep popping up: Bacteroidetes, Akkermansia, Blautia, and Prevotella, among many others.
These bacteria ingest and secrete metabolites that protect or harm health as they live, reproduce, and die, and can trigger neurodegeneration in two major ways, according to Cox. They can interfere with immune function that otherwise might remove harmful proteins such as the amyloid beta that accumulates in Alzheimer’s disease. They can also boost inflammation, an important contributor to the neurological damage in Parkinson’s disease.
“What we found in Alzheimer’s was that Bacteroidetes drove immunosenescence and it blocked this important repair process in which microglia go into the brain and clear out plaques,” Cox said. “In Parkinson’s there’s really strong evidence that the gut microbiota contribute to disease by driving inflammation.”
There are three routes through which gut metabolites affect the brain, according to Francisco Quintana, a professor of neurology at the Brigham whose lab studies the gut-brain axis and neurodegeneration. As in Parkinson’s, they can travel via the nervous system and the vagus nerve. They can also move directly to the brain via the bloodstream, crossing the blood-brain barrier. Third, they can activate immune cells in the gut that travel to the brain and release signaling molecules called cytokines. Those molecules can also cross the blood-brain barrier and trigger the brain’s own immune cells into action.
“I don’t know if it is cause or consequence, but if we model that gut flora, there might be effects on central nervous system pathology — and I think that’s extremely exciting,” Quintana said. “The gut affecting our central nervous system health, our brain health, gives us a unique opportunity to track the brain.”
Forward thinking
In 2020, Aaron Burberry was a postdoctoral researcher in the lab of then-Harvard Professor Kevin Eggan, who had developed a strain of mice that replicated the rare but fatal neurological disease ALS.
Burberry and Eggan created a second population of mice for a lab at the Broad Institute of MIT and Harvard. These animals were genetically identical to the first set and exposed to similar environmental conditions — same food, same light-dark cycles — but they never developed the ALS-like immune response and nervous system inflammation of their predecessors. That divergence sparked a scramble to understand the difference between the two populations, with the evidence eventually pointing to the microbiome. Some microbes present in the guts of Harvard mice were absent in the Broad Institute mice, the researchers discovered.
Burberry and Eggan also found that manipulating the microbiome with antibiotics or fecal transplants from the Broad mice improved or prevented ALS symptoms in the Harvard mice. Burberry, now a professor at Case Western Reserve University, has built on those results, recently identifying a protein produced by immune cells in response to gut microbes that drives up an immune factor called Interleukin 17A, which triggers inflammation in the genetically engineered mice. The FDA has already approved a drug targeting IL-17A, for psoriasis and rheumatoid arthritis, that potentially could be repurposed for ALS. In addition, human trials testing fecal transplant in early ALS patients have begun in Europe.
Work toward gut-based therapeutics for other brain diseases is also moving forward. Rudy Tanzi, an Alzheimer’s specialist and the Joseph P. and Rose F. Kennedy Professor of Child Neurology and Mental Retardation at Harvard Medical School, is developing a “synbiotic” to boost microbiome health. The synbiotic combines probiotics — healthy bacteria — and prebiotics, high-fiber compounds that encourage their growth. Meanwhile, Quintana is using the tools of synthetic biology to engineer microbes — bacteria, yeast, and viruses — to deliver medication that tamps down inflammation before it becomes a problem.
“We might never be able to tell whether it is actually the microbiome exacerbating it or whether it is just reacting to a deeper perturbation in the body,” Quintana said. “But we can look: Is there something in the microbiome that I can use as a biomarker? Can we exploit the microbiome, or perturbations in the microbiome, to develop novel therapies?”
Dustin Tingley.Stephanie Mitchell/Harvard Staff Photographer
Science & Tech
A common sense, win-win idea — and both right, left agree
Poll measures support for revenue-sharing plan on renewable energy that helps states, localities, and environment
Alvin Powell
Harvard Staff Writer
December 5, 2024
6 min read
Democrats and Republicans don’t see eye-to-eye on much. And they often don’
A common sense, win-win idea — and both right, left agree
Poll measures support for revenue-sharing plan on renewable energy that helps states, localities, and environment
Alvin Powell
Harvard Staff Writer
6 min read
Democrats and Republicans don’t see eye-to-eye on much. And they often don’t agree on various aspects of renewable energy. But a recent report finds there is one area in which they’re pretty much in sync: how certain national proceeds should be divvied up.
Results of a recent national poll shows most rank-and-file members of both parties think some revenue from renewable energy produced on federal land should go to states and local communities adjacent to these projects. Right now, it all goes to Washington, D.C.
“I figured that there would be bipartisan support just because of the way people talked about it, but I never expected those sorts of numbers.”
Dustin Tingley
The agreement surprised Dustin Tingley, the Thomas D. Cabot Professor of Public Policy and deputy vice provost for advances in learning, who led the survey.
“I figured that there would be bipartisan support just because of the way people talked about it, but I never expected those sorts of numbers,” Tingley said. “It tells me there are a lot of very reasonable people, common-sense people, in both parties.”
The nationally representative survey of 2,000 Americans, conducted last spring, showed that 91 percent of Democrats and 87 percent of Republicans, along with 87 percent of Independents and 88 percent identifying as “other,” support distributing revenues from solar, wind, and other renewable energy projects sited on federal land to host states and the nearby communities most likely to be impacted by them.
Further, a large majority — 83 percent — said they believe renewables on federal lands have the potential to contribute to U.S. energy needs either “greatly,” or “somewhat.” The party breakdown of those responding “greatly” or “somewhat” was 93 percent Democrat, 72 percent Republican, 82 percent Independent, and 78 percent “other.”
The survey also contained questions about how such funding might be allocated, with respondents suggesting 21 percent to local governments, 27 percent to the federal government, 22 percent to the state, and 30 percent to ecological restoration.
The poll responses reinforce the report’s contention that federal lawmakers should, in this case, do something that climate activists generally don’t recommend: follow the path forged by fossil fuels.
Some 30 percent of the country’s land area is owned and managed by the federal government, mostly the Bureau of Land Management. Coal, oil, and other fossil-fuel-extraction operations pay significant rent and royalties to the government: $7 billion in 2023. Federal law also requires revenue-sharing payments to state and county governments, which amounted to some $4 billion that year.
That money, Tingley said, provides critical support for public programs, including schools and county governments. With the exception of someoffshore wind installations and the nation’s relatively few geothermal plants, revenue from renewable energy projects on federal lands goes directly to the U.S. Treasury.
As of April 2024, the report said, 41 wind, 53 solar, and 67 geothermal projects were permitted on public lands, which, when all are built, will generate 17.3 gigawatts of power, about enough to power 13 million homes. At the end of 2023, there were 150.5 GW of wind and 137.5 GW of solar in the U.S., according to the U.S. Department of Energy.
The different treatment of revenue-sharing between different types of energy generation makes no sense, either to Tingley or to many in the industry and in those nearby communities, said Tingley, who, in drafting the report, also conducted interviews with stakeholders.
“At first, honestly, I couldn’t believe it,” Tingley said about his reaction when he understood the discrepancy. “It’s just so odd. And no matter the angle — if I looked at it as if I’m the Biden administration or a Democrat, or as if I’m a Republican, I was left just puzzled about why it was set up this way.”
Tingley eventually gave up trying to figure out the logic and put it down to a quirk of recent political history. After all, when relevant legislation on solar and wind permitting was being drafted, the U.S. had little renewable energy, so it was a difference that perhaps didn’t matter much.
Today, the situation has changed. Many more wind and solar projects have gone up. And the prospect of getting a significant revenue share might generate local support for renewable power at a time when the nation’s plans to fight climate change demand an increase in installations.
Tingley pointed out that, though members of the two parties might align on this issue as a practical matter, the philosophy behind that agreement likely comes from different points of view.
“There are tons of renewables in Republican areas, and I think people there ask, ‘Why are we keeping all the money with the feds?’” Tingley said. “On the Democrat side, you’re trying to push renewables. And then there’s a common-sense, kind of ‘plain jeans’ feeling of ‘Why are we treating different types of energy differently to begin with?’”
Tingley said the agreement on the topic appears to extend from the grassroots to Congress, where proposals have been drafted on both sides of the aisle. Those proposals, however, have languished for reasons that are unclear. Any shift would take money from the federal budget, but the figures are small enough that they shouldn’t be deal-breakers, Tingley said.
In addition, he pointed out, passage of such legislation would signal to voters that Washington still can pass common-sense policies that benefit ordinary people and local communities, in this case those on the front lines of the energy transition.
“We’re not talking Wall Street; we’re talking Main Street and people living in rural areas,” Tingley said. “People on both sides, when presented with reasonable policy, will support it. There’s not enough of that being brought home by our elected officials because each side just wants to win for their own purposes rather than win for the American people.”
Health
Why be kind? You might live longer.
Illustrations by Liz Zonarich/Harvard Staff
December 5, 2024
1 min read
Take our research-based quiz on biological benefits of being good
Technically, when doing something nice for another person you’re not supposed to think about what’s in it for you. Yet it turns out putting others first is one of the kindest things you can do for yourself. In “The Biology of
Take our research-based quiz on biological benefits of being good
Technically, when doing something nice for another person you’re not supposed to think about what’s in it for you. Yet it turns out putting others first is one of the kindest things you can do for yourself. In “The Biology of Kindness: Six Daily Choices for Health, Well-Being, and Longevity,” Harvard’s Immaculata De Vivo and co-author Daniel Lumera explore the scientific evidence that prosocial behavior can unlock longer, healthier, happier lives. We asked De Vivo — who holds posts at Radcliffe, the Medical School, and the Chan School of Public Health — to help us develop the following quiz based on her book.
Go deeper
De Vivo recommends the following podcasts and book for those interested in learning more.
Helen Vendler.File photo by Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Helen Vendler, 90
Memorial Minute — Faculty of Arts and Sciences
December 5, 2024
6 min read
At a meeting of the Faculty of Arts and Sciences on Dec. 3, 2024, the following tribute to the life and service of the late Helen Vendler was spread upon the permanent records of the Faculty.
Helen Vendler, Arthur
At a meeting of the Faculty of Arts and Sciences on Dec. 3, 2024, the following tribute to the life and service of the late Helen Vendler was spread upon the permanent records of the Faculty.
Helen Vendler, Arthur Kingsley Porter University Professor, was born Helen Hennessy into a devout Boston Irish Catholic family in 1933. She died on April 23, 2024, at 90 years of age and is survived by her beloved son, David; her daughter-in-law, Xianchun; and her grandchildren, Killian and Céline (Harvard Class of 2020). Vendler is interred on “Harvard Hill” in Mount Auburn Cemetery.
The New York Times called Vendler a “Colossus of poetry criticism.” That is true, but how she would have smiled at the image of herself bestriding those turbulent seas! A truer image of her is as a formidably learned proponent of the educational importance of poetry — a knight of poetry, as one colleague described her, riding out to do battle for bards. She was also the most gracious and generous of colleagues, delightful in conversation, meticulous and cheerful in curricular deliberations. Her kindnesses to students and visiting scholars are legendary.
Vendler inspired generations of students at Harvard and beyond with her exquisite sense of poetic form and her swift grasp of what a poet is doing as an artist. Of her many famous books, she seemed proudest of her textbook for students, refined over years, “Poems, Poets, Poetry.” She wrote for everybody, showing newcomers to Elizabeth Bishop or John Ashbery how amply these poets reward close attention. To lifelong specialists on earlier poets, whether Shakespeare or Milton, Herbert or Keats, she revealed new and unsuspected strata of meaning. No other critic of our time, or, indeed, of the past century, has written about poetry with such illuminating power.
Proficient from girlhood in Latin, Spanish, Italian, and French, Vendler might have gone to any elite college then open to women but was forbidden by her devout parents to attend a secular institution. She therefore matriculated at Boston’s Emmanuel College, where she graduated summa cum laude in chemistry and mathematics. Proceeding on a Fulbright Fellowship to the Catholic University of Louvain to study mathematics, she soon changed to the arts and, in pursuit of them, traveled widely in Italy and France. To prepare for the Ph.D. program in English at Harvard, Vendler enrolled as a special student at Boston University. There she formed a lifelong friendship with her teacher Morton Berman (1924–2022), with whom she shared a passion for music and with whom she would later renew her travels in Europe.
At Harvard in the 1950s, when open hostility to women was the norm, Vendler still found wonderful teachers, among them the Miltonist Douglas Bush, the literary theorist I.A. Richards, the Renaissance scholar Rosemond Tuve (a visitor), and especially John Kelleher, creator of the field of Irish studies in the United States. Kelleher’s example inspired the future spokesperson for Irish poetry and world authority on William Butler Yeats and Seamus Heaney.
After taking her Ph.D., in 1960 Vendler went to Cornell University with her then husband, the philosopher Zeno Vendler. Later, as a single mother, she taught freshman writing at Cornell before moving on to appointments at Haverford, Swarthmore, Smith, and Boston University. She always wrote at night, after her son David had gone to bed. Her growing reputation as the finest critic of her generation brought her the honor of being the long-serving poetry critic for The New Yorker. In 1980 Vendler was invited to Harvard but, out of loyalty to embattled colleagues at BU, continued there in alternate terms until she joined Harvard in 1985. She was appointed William R. Kenan Professor of English in 1986 and later served as Associate Dean of the Faculty of Arts and Sciences and as a Senior Fellow in the Harvard Society of Fellows. In 1990 she became Harvard’s first woman University Professor.
Vendler’s books have all become classics, including the stimulating volumes from her five invited lecture series. In her 2001 Haskins Lecture for the American Council of Learned Societies, she quotes Joseph Conrad on “that mysterious power … of producing striking effects by means impossible of detection which is the last word of the highest art.” Not impossible of detection to Vendler, however, who wrote brilliantly on George Herbert, authoritatively on Emily Dickinson, fundamentally on Wallace Stevens, and indispensably on Seamus Heaney, Nobel Laureate and Boylston Professor of Rhetoric and Oratory. Her landmark study of Shakespeare’s 154 sonnets reveals time and again what centuries of commentary have missed. For example, our former summa in chemistry says the phrase “Time’s best jewel” in sonnet 65 describes not the beloved’s natural beauty but rather its “carbonized allomorph.”
The most challenging English-language poets of the past century have been Americans, successors of Wallace Stevens (who studied at Harvard from 1897 to 1900), on whose long poems Vendler achieved pioneering feats of exposition, as she did with the poetry of T. S. Eliot, Robert Lowell, Langston Hughes, John Berryman, Sylvia Plath, Lucille Clifton, James Merrill, A. R. Ammons, James Wright, Frank Bidart, Nobel Laureate Louise Glück, Rita Dove, Lucie Brock-Broido, and the Boylston Professor Jorie Graham, whose genius Vendler recognized early.
Vendler’s many honors include the presidency of the Modern Language Association; 28 honorary doctorates; the Jefferson Lecture, the highest honor the federal government confers in the humanities; plus election to the Norwegian Academy of Sciences and Letters, the American Academy of Arts and Sciences, the American Philosophical Society, which awarded her its Jefferson Medal, and the American Academy of Arts and Letters, which, last year, awarded her its Gold Medal for Lifetime Achievement in Belles Lettres and Criticism. In 2023 Magdalene College, Cambridge University, of which she was an Honorary Fellow, commissioned an oil portrait of her in which she wears on a chain her Irish grandfather’s pocket watch. Vendler’s greatest delight — after her family — was the esteem in which she was held by poets whose work she revered, especially Seamus Heaney and Jorie Graham, who became close friends. She once quoted Czeslaw Milosz to the effect that every achieved poem is a symbol of freedom. This is rarely true of criticism, but it is always true of hers.
Respectfully submitted,
Homi Bhabha Stephanie Burt Stephen Greenblatt Elaine Scarry Gordon Teskey, Chair
Peter Tufano (clockwise from top left), Jim Stock, Robert Stavins, and Jody Freeman. Niles Singer/Harvard Staff Photographer
Science & Tech
Climate change experts see dark clouds ahead
Salata Institute panelists predict legal, regulatory setbacks and areas of hope as Trump administration prepares to take over
Alvin Powell
Harvard Staff Writer
December 4, 2024
7 min read
Climate expert
Salata Institute panelists predict legal, regulatory setbacks and areas of hope as Trump administration prepares to take over
Alvin Powell
Harvard Staff Writer
7 min read
Climate experts expect a second Trump administration to feature multipronged attacks on recent years’ climate change progress, with battles in the courts, in Congress, and involving the enormous administrative power vested in the presidency.
Supporters of efforts to reduce planet-warming fossil-fuel emissions should begin to focus on working to keep gains already made and prepare for a slowdown in progress, according to a panel of specialists gathered at a Salata Institute for Climate and Sustainability discussion Nov. 26 on likely changes ahead as a new administration prepares to take over.
There may, however, also be some bright spots ahead, the experts said, stemming from some states continuing to push for carbon-free energy, the economic momentum behind ever-cheaper clean technology, and from the desire by American businesses to profit from the sale of green products and technology to the world.
“There’s a lot of interest in what lies ahead with the new administration and Congress,” said James Stock, vice provost for climate and sustainability and director of the Salata Institute. “This is pretty complicated, and it’s multifaceted.”
The second Trump administration, with a pro-business bent and taste for deregulation, will bear hallmarks of the first, but with control of the White House, Congress, and a friendly majority on the Supreme Court, the action likely will be more aggressive, said several panelists.
“This version of the Trump administration is not just prepared to roll back federal regulations, but to target the states and the private sector actors that actually want to replace the gap left by the federal government.”
Jody Freeman, Harvard Law School
One prime target for the new administration will be 2022’s Inflation Reduction Act, perhaps the nation’s most ambitious efforts ever to fight climate change. That legislation includes billions of dollars in tax credits, subsidies, and other financial incentives that aim to make carbon-free energy more attractive.
Although some 80 percent of the funding authorized by the legislation has been spent or is under contract, the Biden administration is pushing to get as much money out the door as possible before Inauguration Day, according to Jody Freeman, the Archibald Cox Professor of Law and faculty director of Harvard Law School’s Environmental and Energy Law Program.
That might not be enough, she said, as, with control of Congress as well as the White House, there may be attempts to “claw back” money already awarded and to revise or repeal the law. Among the most endangered targets is the $7,500 tax credit for electric vehicle purchases, she said.
The administration can do quite a lot without having to go through Congress or the courts, Freeman said. At the president’s direction, government agencies tasked with administering climate-related legislation can ease rules or change direction via the governmental regulatory process.
They can alter the government’s position in lawsuits and begin new suits against those pursuing climate-friendly action, as occurred in the first Trump administration, which encouraged an antitrust lawsuit against four automakers that were negotiating with California on auto emissions standards. Similar suits can be pursued against states that challenge federal initiatives, against environmental nonprofits, and against business groups that cooperate to help create a level playing field for competition.
Freeman said these efforts don’t even have to be successful to damage U.S. climate efforts. A widespread “chilling effect” will stem from the attacks themselves, regardless of merit, that may prompt people and organizations to be less aggressive in their activities, or to choose not to fight back.
“This version of the Trump administration, Trump 2.0, is not just prepared to roll back federal regulations, but to target the states and the private sector actors that actually want to replace the gap left by the federal government,” Freeman said. “If that happens to come to fruition, I think that is much more dangerous and much more far-reaching, even if it’s ultimately unsuccessful. All that litigation will help to chill activity, will help to scare people off, and intimidate action, and will also grind it to a halt by tying it up in litigation.”
Stavins, who had recently returned from the annual international climate talks, held this year in Baku, Azerbaijan, said Trump’s re-election loomed over the talks and was a regular topic of conversation among the delegates and other attendees. If Trump again moves to withdraw the U.S. from the Paris Agreement, the timeframe for withdrawal would mean that the nation would no longer be part of the global talks by early 2026.
Other countries, including the U.K., the European Union, and China, indicated they would step up efforts at global leadership in the absence of the U.S.
Beyond withdrawing from the Paris accord, Stavins said that some in Trump’s orbit want the U.S. to withdraw from the underlying treaty that establishes the international framework to collectively address climate change, the United Nation’s Framework Convention on Climate Change, signed in 1992.
Internationally, Stavins said, there is also concern that Trump’s stance may embolden other nations to follow suit.
The churning and uncertainty around the issue are what will be most damaging to the business community, Tufano said. Businesses generally look for opportunities to make a profit, which can occur in the climate space — though profitability will decline if IRA incentives are lost — but stability is key. In the absence of stability, Tufano said, business leaders often will wait to make decisions until the situation stabilizes.
“Businesses react negatively to volatility and uncertainty,” Tufano said. “The amount of jawboning and social media pressure and other kinds of pressure that can be put on firms cannot be underestimated.”
While some industries may be content to slow activities with respect to climate change until the business environment shifts again, some industries can’t afford to, Tufano said. Insurers are already on the front lines of the climate crisis and will still have to respond to climate-related weather disasters regardless of whether their connection to a shifting climate is in political vogue.
Similarly, the low price of installed wind power has made windy states such as Iowa and Texas prime locations for wind farms, a trend unlikely to be reversed. The fight to contain emissions of the potent greenhouse gas methane may also be past the tipping point where political opposition can stall efforts to curb emissions.
The recent launch of methane-sniffing satellites that share their data publicly provides a roadmap for natural gas companies to target leaks, a relatively straightforward task once the leaks are found, Stavins said. The fact that they can then sell gas that otherwise would leak into the atmosphere provides a powerful incentive to lower methane leaks, helping both their bottom line and climate efforts, Stavins said.
“We’re likely to see a lot more action in the oil and gas sector in the United States, but in other countries as well because it’s become newly profitable to fix those leaks,” Stavins said, “a point of optimism.”
Bill Adair. Stephanie Mitchell/Harvard Staff Photographer
Nation & World
Rising ‘epidemic of political lying’
Founder of PolitiFact discusses case studies from his new book that reveal how we got to where we are now
Anna Lamb
Harvard Staff Writer
December 4, 2024
5 min read
Many Americans feel like the spin and outright lying in politics has gotten worse in recent decades. And that it
“For many years, no political journalist that I’d ever worked with nor myself had ever asked a politician: Why do you lie? And so it’s sort of this topic that is omnipresent and yet never discussed. I decided to discuss it, and I decided to ask politicians about it,” said Adair, the Knight Professor of the Practice of Journalism and Public Policy at Duke University.
“They make a calculation — am I going to gain more from making this statement that is false than I’m going to lose. It’s that simple.”
Following several years of research and reporting, Adair ended up zeroing in on about a half dozen people’s stories in his book as case studies that reveal what he calls “truths about lying.”
He also laments that calling out the fabrications and misinformation has not worked to alter the behavior of political actors and that the internet has made it all worse.
“Lying is not a victimless crime. When politicians choose to lie, there are often people who suffer, and often an individual who suffers a great deal, often someone whose reputation is damaged, whose life is turned upside-down,” he said.
At the event, Adair told the story of Nina Jankowicz, a disinformation researcher and writer who had been put in charge of an advisory board within the Department of Homeland Security in 2022 meant to help combat the spread of false information online. She ended up resigning under pressure after opponents of the board spread conspiracy theories online that her real goal was to crack down on free speech.
Adair also recounted the tale of Eric Barber, a city councilor from West Virginia, who became radicalized through Facebook to join the group that attacked the Capitol on Jan. 6, 2021. Adair said that despite serving jail time, Barber still believes that the 2020 election was stolen and Donald Trump won.
Adair also discusses the case of Stu Stevens, a strategist for the 2012 Mitt Romney campaign. Stevens’ group produced an ad making the false claim that then-President Barack Obama was responsible for Jeep shifting production from Ohio to China. Jeep officials publicly stated that claim was false, noting that the company was expanding operations in China but “the backbone of the brand” would remain in the U.S. Adair said Stevens refused to admit the ad was wrong, insisting “it’s technically true.”
So why do politicians bend the truth? And where did it start? According to Adair, it’s a very calculated decision.
“They make a calculation — am I going to gain more from making this statement that is false than I’m going to lose?” he said. “It’s that simple. They want to build support for the base, and they believe that lie, in some small way, will help them do that.”
While both sides lie, Adair says his research finds Republicans do it more often. He writes in his book that from 2016 to 2021, 55 percent of the statements made by Republicans and investigated by PolitiFact were false, while 31 percent of those made by Democrats were.
“I asked that question of a whole bunch of Republicans and former Republicans who were willing to talk to me, and I heard a lot of answers,” Adair said. “One was that it’s just become part of their culture.”
“We went state by state, and we found that in half the states there are no political fact-checkers. That’s like having interstate highways where there’s no risk of getting a speeding ticket.”
Denver Riggleman, a former GOP congressman from Virginia, told Adair that Republicans view their work as part of an epic struggle, and that in that struggle anything is OK.
Adair took pains, however, to underscore that Democrats also lie. For example, a PolitiFact check on Joe Biden in May finds he wrongly stated that the rate of inflation he inherited when he took office was much higher than it actually was.
Overall, he went on to say, fact-checking is not working.
“Fact-checking is not stopping the lies. Fact-checking is not putting a serious dent in the lies,” Adair said.
“There’s plenty of fact-checkers who check politicians when they are running for president, but what about the senators and governors and members of the U.S. House?” he said. “We went state by state, and we found that in half the states there are no political fact-checkers. That’s like having interstate highways where there’s no risk of getting a speeding ticket.”
That leads Adair to his first recommendation.
“We need to be creative in getting [fact-checking] to more people, in using it as data so that we can suppress misinformation,” he said. He added that in addition to increasing the volume of fact-checkers in underreported areas, there needs to be more conservative organizations doing their own fact-checking.
“This can’t just be for people who listen to NPR and read The New York Times,” he said.
Adair suggests that AI might help fact-checkers by allowing them to track lies across multiple platforms. He also pointed to efforts by Facebook to fact-check posts on their site.
“I think that we need to reboot how we do this and how we think about this, because the lies are running rampant,” he said.
Beijing’s central business district.Creative Commons
Work & Economy
How China tariffs could backfire on U.S.
Asia scholar says they could spark higher prices, supply-chain disruptions for Americans — and possibly help Beijing weaken our ties to allies
Christina Pazzanese
Harvard Staff Writer
December 3, 2024
long read
President-elect Donald Trump’s longstanding plans to hit China with
Asia scholar says they could spark higher prices, supply-chain disruptions for Americans — and possibly help Beijing weaken our ties to allies
Christina Pazzanese
Harvard Staff Writer
long read
President-elect Donald Trump’s longstanding plans to hit China with stiff tariffs would likely deal a blow to China’s already faltering economy, but it could also trigger some unintended negative consequences for the U.S. economy and foreign relations, economists say.
Trump warned last week that on his first day back in office he will impose 25 percent tariffs on goods from Mexico and Canada and an additional levy of 10 percent on Chinese imports. (He said during the campaign he would hit China with tariffs of 60 percent or more.) He said the nation’s largest trading partners need to take swifter, harsher action to halt the flow of illegal migrants and drugs into the U.S.
A revived trade war would further destabilize China’s economy, but economists and tax experts caution it would also harm the U.S. economy by increasing prices for American consumers and could lead to supply chain disruptions, labor shortages, and a currency war with China. In addition, it could provide China with new opportunities to get closer to traditional U.S. allies in Europe, the U.K., Australia, and Japan.
Rana Mitter, S.T. Lee Professor of U.S.-Asia Relations at Harvard Kennedy School, spoke with the Gazette about how China is viewing the prospect of new tariffs and preparing to respond. This interview has been edited for clarity and length.
The Chinese economy is already facing headwinds from a battered housing market and sluggish consumer demand. How is Beijing viewing the possibility of another trade war with the U.S.?
There are at least two different strands of thinking, which point in different directions. One of them is extreme concern about the way in which a tariff policy could essentially make China’s global export drive much more difficult to achieve, particularly into U.S. markets, which still remain very important despite the political difficulties between the two countries.
The other is much more about medium-term thinking. Some think that the imposing of tariffs could be the beginning of some new, hard-nosed, realistic negotiation with the United States, which could end up being a version of the Phase One trade deal that did exist under the first Trump administration. I would say the first is more dominant, as far as I can tell. But that second thought, that there might be an opportunity for China, is not absent.
“I think the biggest fear on the Chinese side at the moment is uncertainty on what the phrasing of ‘60 percent tariffs on goods coming in from China’ actually means — or the most recent statement that there might be an additional 10 percent.”
Rana Mitter
What worries China the most right now?
I think the biggest fear on the Chinese side at the moment is uncertainty on what the phrasing of “60 percent tariffs on goods coming in from China” actually means — or the most recent statement that there might be an additional 10 percent. Defining where goods come from isn’t simple; there are different rules of origin; there are different components. Many products that are very popular in the U.S. and the world — Apple smartphones would be a very good example — have many components from China.
So, the question is: What does it actually mean to impose 60 percent tariffs? Until you know the answer to that question, you can’t very easily plan for it. I suspect that is part of the intention. The aim is to make it clear what direction of travel is on this issue, not to give a detailed, laid-out plan as to how it’s going to operate. And for many of the Chinese, I suspect they see this as the starting point for negotiation, and they see a new Trump administration wanting to be on the front foot in terms of that negotiation.
In 2023, China fell behind Mexico as the top supplier of U.S. imports. The value of China’s share of U.S. imports in semiconductors, smartphones, and laptops was 35 percent lower than when Trump first imposed some tariffs in 2017. How damaging could a U.S. tariff of 60 percent or more be to China’s economy? And could China make up for that elsewhere?
First of all, yes, it would make things difficult. Clearly, export of manufactured goods into the United States is a very significant part of China’s economy. But it’s worth remembering that other key markets, including the European Union and Japan, are also part of China’s strategy of selling to highly developed, advanced economies. Nonetheless, the U.S. is a very important market, and in fact, even during the last few years of U.S.-China political controversy, trade figures between two sides have actually often gone up rather than down. So, it is significant, there’s no doubt about that.
In terms of opening up new markets, there’s certainly very, very strong efforts, and have been for some years, to try and do that.
Think about the signature policy that China has used in terms of international exports and foreign direct investment, what’s been known as the Belt and Road Initiative [a global infrastructure development plan to connect Asia with Africa and Europe to strengthen China’s geopolitical and economic influence]. In the last year or two, the term GDI, Global Development Initiative, has been much more widely used by the Chinese for the next phase of their plans.
The aim is essentially to create new and higher value markets in emerging economies — Southeast Asia, Latin America, and to some extent, Sub-Saharan Africa, although the latter is still of more interest in terms of raw materials than it is in terms of new markets for sales. Or think about EVs (electric vehicles), both Chinese exports of EVs and the export of intellectual property, including Chinese technology, to areas like Southeast Asia is becoming a bigger factor than it would have been four or five years ago even.
Nonetheless, these are still small markets compared to the number of Chinese goods that are sold into very advanced markets like the United States — half a trillion dollars according to U.N. figures.
Trump has been promising for some time to impose additional tariffs if re-elected. Has China been preparing for that possibility?
Yes, they’ve been preparing for quite some time for this possibility. Since it became clear that President Trump would likely be the Republican candidate, and then could quite possibly win, there has been plenty of strategizing in Beijing about what that outcome would mean in a whole variety of areas, including security, as well as trade.
On trade, the question of how China tries to move to protect their markets and also deal with the shaky state of the domestic economy has been a really key question. But there is no clear answer yet.
If you look at the economic policies the Chinese government has undertaken in the last few months, it involves repeated use of fiscal stimulus to try to stimulate domestic consumer spending. But since China is very, very determined to maintain a global trade surplus, it’s going to be much harder for them to use domestic consumption as a means of boosting the economy. So, exports still really matter.
Getting around that involves a policy decision they don’t want to make: to release large amounts of the savings that ordinary Chinese have in their accounts, reduce their trade surplus, and redirect spending into the domestic consumer market. That is something that has been advocated by Chinese policymakers for more than 20 years. They always step back from it because, in the end, exporting more has seemed more politically attractive and a solution more suited to where they are at the moment in terms of global supply chains.
Which countries stand to benefit most from a decline in Chinese imports to the U.S.? Is anyone poised to step in to meet U.S. demand?
You put your finger on the key issue. Filling that gap in short order will be very, very difficult. There is a reason that China has become so dominant over 30 years. If there was some reason — terrorists or a conflict or something else — that made China no longer viable, then India is probably one place that would attract investment on that front. But it would take time to bring its supply chains and its technical capacity up to standards.
Vietnam, but of course Vietnam borders China, and it’s possible that issues with supply-chain problems might well affect Vietnam more directly. There are also places where you can get niche manufacturing of various sorts done. But in terms of that kind of higher-value-added manufacturing, that demands technical skills, lots of components, supply chains, those are very complex things.
A slightly different issue, but not unrelated, is the dominance that Taiwan has on the very-high-end semiconductor market. That’s still a very vulnerable part of a global supply chain and that will remain relevant in terms of trying to shift capacity from China. Because it’s never just about China, it’s also about the things that get sent to and sent from China as part of the wider manufacturing process.
Harvard economist Larry Summers recently said if the U.S. takes a broad brushstroke approach to tariffs on imports, that may provide Beijing with a ready excuse for China’s own internal economic problems, further straining U.S.-China relations. Do you share that view?
I think that’s quite plausible, but I’d say there’s another “yes, and.” It also provides an opportunity for something else that China could do that the U.S. would find unattractive.
What’s being proposed is not just a 60 percent tariff on Chinese goods, but also 25 percent on all goods from Mexico and Canada. [And Trump said during his campaign that European Union nations might also face tariffs.] That gives China an opportunity to talk to the EU, to talk to mid-sized, independent economies like Australia, the U.K., Japan, and say, “Because we are all being targeted by these tariffs at different levels, it makes more sense for us to find some common cause.”
It would be a real reversal if the United States chose to undertake a trade policy that got the Chinese and Europeans closer to each other rather than the U.S., as is traditional, being close to its democratic allies.
So that may be an unintended consequence that could have lasting harm to the U.S. well beyond spiking prices for American consumers?
It opens an opportunity for China that doesn’t exist at the moment but would exist if there was a very wide-ranging, broad-brush approach on tariffs imposed on all imports. Since all advanced economies do import as well as export, they’re going to find themselves very vulnerable.
And if they feel the United States is trying to prevent exports into the U.S. rather than encourage them, they will look to other large markets. There aren’t that many of them of that size and even larger in the world, but China is very clearly one of them.
Arts & Culture
The 20th-century novel, from its corset to bomber jacket phase
Machado de Assis (clockwise from upper left), Gertrude Stein, Colette, and Ernest Hemingway.Photo illustration by Liz Zonarich/Harvard Staff
Liz Mineo
Harvard Staff Writer
December 3, 2024
9 min read
In ‘Stranger Than Fiction,’ Edwin Frank chose 32 books to represent the period. He has some regrets.
In his
The 20th-century novel, from its corset to bomber jacket phase
Machado de Assis (clockwise from upper left), Gertrude Stein, Colette, and Ernest Hemingway.
Photo illustration by Liz Zonarich/Harvard Staff
Liz Mineo
Harvard Staff Writer
9 min read
In ‘Stranger Than Fiction,’ Edwin Frank chose 32 books to represent the period. He has some regrets.
In his new book, Edwin Frank ’82 charts the history of the 20th-century novel through 32 key works, from Fyodor Dostoevsky’s “Notes from Underground” and H.G. Wells’ “The Island of Dr. Moreau” to Marcel Proust’s “In Search of Lost Time” and W.G. Sebald’s “Austerlitz.”
The Gazette interviewed Frank — founder and editorial director of the publishing house New York Review Books — about “Stranger Than Fiction: Lives of the Twentieth-Century Novel,” including why he selected certain titles, controversial omissions, and his hopes for the future of the art form. This interview was edited for clarity and length.
Your book traces the trajectory of the 20th-century novel through 32 titles. What made, in your view, those works and authors exemplary of that century?
The authors in the first and largely the second part of the book are authors who represent new beginnings and new ways of thinking about the novel. H.G. Wells invents a certain kind of popular fiction. André Gide invents a certain kind of art novel that stands apart from the popular 19th-century novels. Kipling and Colette are looking at what it is to be at the start of a new century and to be young people, and what it means to hope for a new world or to be impatient with the old world. I include Gertrude Stein and Machado de Assis because they represent new ways of writing that emerge in the New World, which of course, has a shorter history of producing novels. Most of those writers were at the beginning of the last century young people, and I wanted to map the new terrain, and these writers serve to do that.
In a way, the book has behind the scenes a single character: the 20th-century novel. You could say that at the beginning she dresses Edwardian style, not always happily, and by the end, she’s wearing a bomber jacket. I wanted to explore the changes that took place over the course of a lifetime of the novel as literary form.
In the second part of the book, the novelists are dealing with issues having to do with the conclusive destruction of the Victorian ways of life by World War I. They know they live in a new world altogether, one where all sorts of old codes have been destroyed, and the question is how to chronicle this new world.
“I thought that the book should be introducing people to wonderful writers who are less well known to the Anglosphere and suggesting ways in which books that sometimes seem daunting to read are entirely engageable books and still very much alive.”
Were you worried that many of the novels you chose are not well known and that those that are well known are not even read by many people?
I thought that the book should be introducing people to wonderful writers who are less well known to the Anglosphere and suggesting ways in which books that sometimes seem daunting to read — let’s say Robert Musil’s “The Man Without Qualities” — are entirely engageable books and still very much alive. I saw that as being, frankly, part of my own story of expanding publication and translation of books from different parts of the world so that readers learn to read across barriers that once seemed challenging.
You include American authors Ralph Ellison, Gertrude Stein, and Ernest Hemingway. Why not William Faulkner or others that some may see as glaring omissions?
The conception of the book was international, and the presence of American writers had to be circumscribed. And even so, certainly the largest contingent of writers in the book reflects my own linguistic competence. I speak briefly about Faulkner and state his importance. Several people said that the omission of Dos Passos is, just from the point of view of the international novel, perhaps the most glaring one because along with Faulkner and Hemingway, Dos Passos is undoubtedly the single most influential American writer on writers abroad in the last century. The panoramic novel he invents is a major genre, and I’m very fond of Dos Passos. It was with some regret.
With Stein, I wanted to suggest that she does pass on to, certainly Hemingway and Faulkner, a sense of American literature as posing a question of scale; what kind of sentence can be big or small enough for the almost unimaginable uncertainties that the new world opens up. We often forget how provisional a country America was, and perhaps still is. Stein realized how an open form could particularly address that situation. As she famously said, “There is no there there.” That is Stein’s sort of peculiar genius. Even if we don’t think of her as having written a book that is as beloved as any of those writers’ books, she made a remarkable contribution.
There are other novels I wrote about, but they ended up on the cutting-room floor. For example, Naguib Mahfouz’s “The Cairo Trilogy,” which looks back to 19th-century European novels, but also introduces a heady, lyrical, almost fantastical dream narrative that he takes from the ancient tradition of Arabic writing. And then there is also the surrealist Louis Aragon, who didn’t make the cut. I regret that because I wanted to bring out how surrealism, largely neglected or seen as a visual art in the Anglophone world, was a major contributor to the novel in the 20th century. Magical realism came out of surrealism.
What influence, if any, did the novels written in the 18th and 19th centuries have in this literary form in the 20th century?
The novel is a popular form starting really in the 18th century. But in the 19th century, it becomes truly popular, and the growth of literacy and industry allows novels to be produced on a larger scale for a larger audience. In a way, the 20th-century novel is impatient with the novel’s success. It’s impatient to prove that the novel is a fully serious form of art and not just a popular form of art. The novel is also skeptical of the political and social arrangements that have emerged in the 19th century; wanting more freedoms for individuals, sexual freedoms, artistic freedoms, and freedom to talk about the whole range of lived experience. If the 19th-century novels tend to balance the claims of self and society, saying that that balance is the precondition for a life of, as Freud would say, “ordinary unhappiness,” or even perhaps a happy life, in the 20th century, that balance becomes suspect, and the novel explores the ways in which things can be set out of balance.
What do Gabriel García Márquez’s “One Hundred Years of Solitude,” or Elsa Morante’s “History,” which are in the last part of the book, say about the end of the century?
The last part was the part where books surprised me most often. I didn’t quite know how I was going to end the book. I thought it should end the way a pop song ends, by fading out, but you have to fade out on a strong chorus. As it happened, the book was writing me as much as I was writing the book. Those post second World War books end up as a person does: entering middle age and looking back at a history that is in many ways already set. There are novels that stand as models of innovation, but they are now older novels. You get to a book like “One Hundred Years of Solitude,” whose very title announces itself as a book of a century, though it never mentions the 20th century, but it is a book, in some sense, about what is the meaning of these 100 years that we have lived through. And that struck me a good deal. Books like Georges Perec’s “Life: A User’s Manual” or Elsa Morante’s “History,” or García Márquez’s novel have a quality of trying to sum up, and I hadn’t really anticipated that. I was getting to the end of my book, and I suddenly realized that, in fact, a lot of books from the last part of the century were about summing up; they were about ending.
What are your hopes and concerns about the future of the novel and its place in the cultural conversation?
I would worry that the novel becomes a sort of a special property of the educated classes, that it becomes a little precious and loses its connection to the larger life of society and to a whole range of different kinds of people who have emerged in modern societies.
It strikes me that here in America we are living through changing times, and it’s remarkable to me how few novels there are that deal with — as Dickens, a brilliant stylist in his own right — financiers, scallywags and shameless politicians and what you will. I hope that those novelists do emerge. People always talk about how people no longer have the stamina to read long books, but then you have George Martin’s books, which are very long indeed, and people seem to gobble them up. Those books have a range of characters and events that shows an appetite to be comprehensive. And recently, Karl Ove Knausgård’s “My Struggle” too. I think, to some extent, that the literary novel is still a little overshadowed by the sheer range of accomplishment in the previous century and is struggling to find a new footing, a new sensibility and a new way of responding to the new world that we inhabit.
Nation & World
‘Because Larry has shown up for us’
Friends, colleagues gather for 70th birthday conference honoring economic scholar, former Treasury Secretary and University President Lawrence Summers
Alvin Powell
Harvard Staff Writer
December 2, 2024
4 min read
Jason Furman (from left), Olivier Blanchard, and Brad DeLong. Photos by Niles Singer/Harvard Staff Photographer
In introdu
Friends, colleagues gather for 70th birthday conference honoring economic scholar, former Treasury Secretary and University President Lawrence Summers
Alvin Powell
Harvard Staff Writer
4 min read
Jason Furman (from left), Olivier Blanchard, and Brad DeLong.
Photos by Niles Singer/Harvard Staff Photographer
In introducing the final panel, Gene Sperling, who directed the National Economic Council for Presidents Bill Clinton and Barack Obama, remarked, “This is not a roast.”
But the recent economic policy conference marking Lawrence H. Summers’ 70th birthday was often roast-like — although always affectionate — interspersed with anecdotes from computer labs during Summers’ student days, the halls of Washington, D.C., and the president’s office in Mass Hall. Pointed comments about economic concepts prompted laughter, as did Summers — seated in the front row — who offered some good-natured rebuttals to the ribbing.
The gathering featured panels on Summers’ impact on modern finance, labor and public economics, and macroeconomics and policy. Speakers described a colleague and friend who has had a deep impact on those around him. His trademark probing questions have pushed others to think deeper, while his public positions have made a difference on topics as disparate as the recent rise and fall of inflation, passage of the Affordable Care Act, and his early recognition, in 1992, of the importance of educating girls in the developing world.
Summers offered some good-natured rebuttals to the ribbing.
“No one was talking about this, but Larry did, and he single-handedly took that issue from something that education ministers care about to something finance ministers care about,” said former Meta chief operating officer Sheryl Sandberg, “And we all know the power difference between those two posts. Literally millions and millions of girls owe a change in their lives and futures to that speech.”
Today, Summers is the Charles W. Eliot University Professor and the Frank and Denie Weil Director of the Mossavar-Rahmani Center for Business and Government at the Kennedy School. His career spans studies at MIT and Harvard; the World Bank, where he was chief economist; the U.S. Treasury department, where he was secretary from 1999 to 2001; Harvard’s president’s office from 2001 to 2006; and the National Economic Council, which he directed from 2009 to 2011 under Obama.
Panelists painted a portrait of a scholar and public servant who is an innovative thinker and fearless in his thoughts and beliefs: Summers at one point remarked about a fundamental concept he still disagrees with, to knowing laughter. “I’ve lost that argument with the world, largely. I’m aware of that, but not to the extent of giving it up.”
Sheryl Sandberg described Summers’ impact on her career as profound.
Jason Furman, former chair of the Council of Economic Advisors and HKS’ Aetna Professor of the Practice of Economic Policy, described Summers’ ability to extract knowledge from those around him by focusing on a single issue or question and probing it until he was satisfied he had learned all he could. UC Berkeley Professor Brad DeLong said Summer’s questioning style went both ways: People learned more than facts and figures from him. They learned how to think differently.
“Larry’s nearly unique edge, I think, is an extremely, extremely sharp eye for what pain points are about to become salient, over and over seeing when things are changing in the macro economy so we really need to change our models to deal with skating where the puck is going to be,” said DeLong, who has been a co-author with Summers. “Because the important questions are about now and the next decade. You write even a good paper about an important question in macro from a decade ago, and you have written a paper about an unimportant question.”
Sandberg, who graduated from Harvard Business School in 1995, said Summers’ impact on her career has been profound. She met him as a student, he advised her thesis, gave her a job at the World Bank when he was chief economist, and later at the Treasury, where she was his chief of staff. Through her career he was always willing to listen, she said, and she knows he listened to others even when they were facing public scrutiny, a time when many would shrink from associating with them.
“He never worried that he would somehow get dragged into someone else’s mess. He just showed up,” Sandberg said. “I know all of us here showed up for this day because Larry has shown up for us.”
Health
Score another point for the plants
Study finds 1:2 ratio of plant to animal protein lowers risk of heart disease
Maya Brownstein
Harvard Chan School Communications
December 2, 2024
4 min read
Increasing the ratio of plant-based protein in your diet may reduce your risk of cardiovascular disease and coronary heart disease, finds a new study led by researchers at Harvard T.H. Chan S
Study finds 1:2 ratio of plant to animal protein lowers risk of heart disease
Maya Brownstein
Harvard Chan School Communications
4 min read
Increasing the ratio of plant-based protein in your diet may reduce your risk of cardiovascular disease and coronary heart disease, finds a new study led by researchers at Harvard T.H. Chan School of Public Health.
According to the researchers, these risk reductions are likely driven by the replacement of red and processed meats. The researchers also observed that a combination of consuming more plant protein and higher protein intake overall provided the most heart health benefits.
While global dietary guidelines recommend higher intake of plant protein, the ideal ratio of plant to animal protein has remained unknown. The study is the first to investigate this ratio and how it impacts health, specifically heart health.
Risk reductions are likely driven by the replacement of red and processed meat with several plant protein sources, particularly nuts and legumes.
“The average American eats a 1:3 plant to animal protein ratio. Our findings suggest a ratio of at least 1:2 is much more effective in preventing cardiovascular disease. For coronary heart disease prevention, a ratio of 1:1.3 or higher should come from plants,” said lead author Andrea Glenn, visiting scientist in the Department of Nutrition. Glenn worked on the study as a postdoctoral fellow at Harvard Chan School and is now an assistant professor in the Department of Nutrition and Food Studies at NYU Steinhardt.
The study was published Dec. 2 in the American Journal of Clinical Nutrition.
The researchers used 30 years of data on diet, lifestyle, and heart health among nearly 203,000 men and women enrolled in the Nurses’ Health Studies I and II and the Health Professionals’ Follow-up Study. Participants reported their dietary intake every four years. The researchers calculated each participant’s total protein intake, measured in grams per day, as well as their specific intakes of animal and plant proteins. Over the course of the study period, 16,118 cardiovascular disease cases, including over 10,000 coronary heart disease cases and over 6,000 stroke cases, were documented.
After adjusting for participants’ health history and sociodemographic and lifestyle factors, the study found that eating a higher ratio of plant to animal protein was associated with lower risks of cardiovascular disease and coronary heart disease. Compared to participants who consumed the lowest plant to animal protein ratio (~1:4.2), participants who consumed the highest (~1:1.3) had a 19 percent lower risk of cardiovascular disease and a 27 percent lower risk of coronary heart disease. These risk reductions were even higher among participants who ate more protein overall. Those who consumed the most protein (21 percent of energy coming from protein) and adhered to a higher plant to animal protein ratio saw a 28 percent lower risk of cardiovascular disease and a 36 percent lower risk of coronary heart disease, compared to those who consumed the least protein (16 percent of energy). No significant associations were found for stroke risk and the ratio; however, replacing red and processed meat in the diet with several plant sources, such as nuts, showed a lower risk of stroke.
The researchers also examined if there’s a point at which eating more plant protein stops having added benefits or could even have negative implications. They found that risk reduction for cardiovascular disease begins to plateau around a 1:2 ratio, but that coronary heart disease risk continues to decrease at higher ratios of plant to animal protein.
According to the researchers, replacing red and processed meat with plant protein sources, particularly nuts and legumes, have been found to improve cardiometabolic risk factors, including blood lipids and blood pressure as well as inflammatory biomarkers. This is partly because plant proteins are often accompanied by high amounts of fiber, antioxidant vitamins, minerals, and healthy fats.
“Most of us need to begin shifting our diets toward plant-based proteins,” said senior author Frank Hu, Fredrick J. Stare Professor of Nutrition and Epidemiology at Harvard Chan School. “We can do so by cutting down on meat, especially red and processed meats, and eating more legumes and nuts. Such a dietary pattern is beneficial not just for human health but also the health of our planet.”
The researchers pointed out that the ratios they identified are estimates, and that further studies are needed to determine the optimal balance between plant and animal protein. Additionally, further research is needed to determine how stroke risk may be impacted by protein intake.
The Nurses’ Health Studies and Health Professional Follow-up Studies are supported by National Institutes of Health grants UM1 CA186107, R01 CA49449, R01 HL034594, U01 HL145386, R01 HL088521, U01 CA176726, R01 CA49449, U01 CA167552, R01 HL60712, and R01 HL35464.
Shriya Srinivasan, artistic director of Anubhava Dance Company (second from left), performing at the Harvard Art Museums.Photo by Jodi Hilton
Arts & Culture
Dance the audience can feel — through their phones
Eileen O’Grady
Harvard Staff Writer
December 2, 2024
5 min read
Engineer harnesses haptics to translate movement, make her art more accessible
Shriya Srinivasan danced with preci
Dance the audience can feel — through their phones
Eileen O’Grady
Harvard Staff Writer
5 min read
Engineer harnesses haptics to translate movement, make her art more accessible
Shriya Srinivasan danced with precise steps, using graceful flicks of her wrists to depict a heroine holding a mirror and applying makeup and perfume, her expressions lit by hope and excitement. Behind her, centuries-old Indian watercolors depicted similar heroines.
The assistant professor of bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences was performing a bharata natyam dance about a common archetype in Indian paintings and dance — a vasakasajja nayika, or heroine eagerly preparing to meet her lover — for a recent event at the Harvard Art Museums. Before the dance, she explained to the audience how the brain’s prefrontal cortex heightens feelings of excitement and anticipation in love by tapping into memories and activating reward centers.
“As a dancer, I aim to enter the emotional and physiological state of the character I am playing, inducing a faster heart rate or slowing the breath, to simulate anxiety or deep loss, for example,” she said. “Mirror neurons in the viewer then assimilate these cues and allow them to resonate with the emotional experience and catharsis of the character.”
A recent collaboration between the lab and Anubhava led to the creation of an app that allows audience members to feel dancers’ movements through a smartphone’s vibrations, a project featured last month on the PBS Nova docuseries “Building Stuff.”
“The scientific question at hand was: How can we enhance the experience of dance, reaching beyond just audio and visual input into tactile or other forms of sensory input?” Srinivasan said.
Her research and development team, which included Isabella Gomez ’24 and Krithika Swaminathan, Ph.D. ’23, developed custom sensing devices that are placed on the ankles of Anubhava dancers to capture and classify their complex footwork into patterns. A smartphone app transmits the movements into audience members’ hands. Srinivasan says the technology has the potential to make dance performances more accessible for the lay viewer, as well as visually- or hearing-impaired people.
“Choreographing a piece is akin to designing a system — both involve carefully crafting elements to achieve a specific effect.”
Shriya Srinivasan
Srinivasan, assistant professor of bioengineering, in her office.
Photo by Grace DuVal
To make the haptic feedback stimuli convey the feel of the footwork, researchers set the vibrations to different intensity levels. Light, flowing movements were represented by vibrations targeting surface-level mechanoreceptors in the skin, while more intense, punchier movements penetrated to deeper skin layers, Srinivasan explained. The project culminated in a dance titled “Decoded Rhythms” for an audience at the ArtLab, where Srinivasan did a 2023-2024 faculty residency.
“For me, dance and engineering are similar in process,” Srinivasan said. “Choreographing a piece is akin to designing a system — both involve carefully crafting elements to achieve a specific effect. Just as engineers design a system to meet certain requirements, dancers create choreography to evoke a particular emotion or reaction from the audience. It’s about problem-solving and design.”
Srinivasan, who grew up dancing bharata natyam under the tutelage of her mother Sujatha Srinivasan, established Anubhava in 2015 with co-founder Joshua George in the hopes of creating a space for Indian forms in the American dance world while also merging arts, science, and humanities onstage.
“There’s a high level of rhythmic and mathematical complexity that goes into the choreography that we produce that might not always translate to an audience if they’re not familiar with the style of music that we utilize, or if they’ve not been trained in the dance form,” George said.
Since this collaboration, Srinivasan said Anubhava has been diving deeper into neuroscience, psychology, and mental health, incorporating portrayals of emotions such as fear and anxiety, which she said are not commonly explored in Indian classical dance tradition, into their recent performances.
“I find it immensely fulfilling to engage in work at the intersection of disciplines,” Srinivasan said. “Exploring a problem from different perspectives can help you envision solutions that aren’t visible from traditional silos.”
Srinivasan is especially interested in further research on how physiological changes in the body of a dancer portraying emotions onstage might evoke a similar response in audience members.
“There are vast opportunities to study why the world makes us feel the way we do. When I experience art, it evokes a certain emotional response in me. Understanding why is deeply fundamental to the work of an artist, but doing so with the lens of science gives me this tangible way to say, ‘OK, if I modulate ABC, I can get somebody to feel XYZ.’ To me, that’s nuanced insight.”
Health
How HIV research has reshaped modern medicine
Colorized transmission electron micrograph of an HIV-1 virus particle (yellow/gold) budding from an infected cell. Credit: NIAID/NIH
Shafaq Zia
HMS Communications
November 27, 2024
long read
Decades of scientific work turned the tide on a fatal disease and yielded insights into immunity, vaccines, and more
In 1981, fresh out of medica
Colorized transmission electron micrograph of an HIV-1 virus particle (yellow/gold) budding from an infected cell.
Credit: NIAID/NIH
Shafaq Zia
HMS Communications
long read
Decades of scientific work turned the tide on a fatal disease and yielded insights into immunity, vaccines, and more
In 1981, fresh out of medical school, physician-scientist Bruce Walker began his internship at Massachusetts General Hospital. One day, a young patient showed up with an unusual cluster of infections and cancers. Baffled and powerless to treat him, Walker and his colleagues could only watch as the patient quickly succumbed to the mysterious condition.
“I distinctly remember the first case we saw at Mass General,” said Walker, who is the Phillip T. and Susan M. Ragon Professor of Medicine at Harvard Medical School and the director of the Ragon Institute of Mass General, MIT, and Harvard. “The attending physician said that although we didn’t know what this condition was, we probably would never see another case like it.”
Two weeks later, another patient came in with the same set of symptoms. It quickly became clear to Walker and his colleagues that they weren’t dealing with a rare disease — it was the beginning of a new epidemic.
The baffling condition was acquired immunodeficiency syndrome (AIDS) — the most advanced stage of infection with the human immunodeficiency virus (HIV), which attacks and destroys infection-fighting immune cells. By 1993, HIV had become the leading cause of death in Americans aged 25-44 years.
In the 40-plus years since it was identified, scientists have made notable progress against HIV, transforming the infection from a death sentence into a manageable chronic condition, one that affects some 1.2 million people in the United States and nearly 40 million worldwide.
This decades-long quest for a cure for HIV has also yielded broader insights that have implications for the treatment of COVID-19, cancer, and other diseases.
From molecular insights to frontline medicines
Since the identification of HIV as the cause of AIDS, basic science and animal research have played a critical role in illuminating the virus’ complex behavior.
Some of the pivotal studies toward unraveling the structure, biology, and behavior of HIV have emanated from labs across Harvard Medical School. Using a range of imaging techniques, Stephen Harrison’s lab has identified key portions of HIV and studied the evolution of HIV antibodies, which is critical to understanding how the immune system interacts with the virus. The work of Joseph Sodroski, Bing Chen, and Alan Engelman has elucidated how HIV enters host cells and interacts with cell receptors, studying the structure and behavior of the virus’ protein envelope during this process.
This research has illuminated how HIV integrates its genetic material into host cell DNA, a crucial step in the virus’ life cycle. These insights have enhanced vaccine and therapeutic development by revealing how broadly neutralizing antibodies work and guiding the design of new immune-targeting strategies.
Early analyses of patient samples revealed that HIV is a human retrovirus — a type of virus that converts its RNA into DNA upon infecting a host cell. This tricks the host cell into copying the virus’ genetic material into its DNA as part of the cell’s normal replication cycle. The maneuver enables it to use the host cell machinery to make more viruses. HIV specifically goes after CD4 T lymphocytes or so-called helper T cells. These white blood cells coordinate immune response by signaling other immune cells to fight invaders. The virus begins by hijacking the cells’ molecular machinery to assemble thousands of viral particles, which go on to infect other CD4 T cells, spreading the pathogen throughout the body.
Today, the standard treatment for HIV is antiretroviral therapy (ART) — a combination of HIV medications, typically taken daily, that disrupt the virus’ replication cycle. When taken consistently, ART can lower the amount of actively replicating virus in the body — or viral load — to undetectable levels, lowering risk of transmission and allowing people with HIV to live nearly as long as uninfected individuals.
ART has also proved to be useful as a pre-exposure prophylaxis (PrEP) — an approach that can prevent up to 99 percent of sexually transmitted HIV infections from developing after exposure. Notably, a new class of medicines has raised hopes as a game-changer in HIV prevention. Two recent clinical trials of more than 7,500 cisgender men and transgender and nonbinary people showed that twice-a-year injections with the long-lasting drug lenacapavir prevented HIV infections in nearly all participants.
Yet, millions around the world are already infected. Once inside the body, HIV persists because of its remarkable ability to hide within healthy CD4 T cells, where it can lie dormant for years without triggering an immune response, said Daniel Kuritzkes, HMS Harriet Ryan Albee Professor of Medicine and chief of the division of infectious diseases at Brigham and Women’s Hospital.
Although these latent reservoirs of HIV do not actively produce new virus particles, they can reawaken at any time, leading to active HIV infection. This chronic immune activation among infected people — even when the virus is kept at bay — can amplify the risk for several chronic conditions.
“People living with HIV often have elevated markers of inflammation. This chronic immune activation can predispose people to long-term complications, including cardiovascular illness.”
Daniel Kuritzkes, chief of the division of infectious diseases, BWH
“People living with HIV often have elevated markers of inflammation,” Kuritzkes said. “This chronic immune activation can predispose people to long-term complications, including cardiovascular illness.”
Indeed, research has shown that people with HIV have a somewhat elevated risk for cardiovascular disease, diabetes, kidney disease, and certain types of cancer. Now, the latest research from Advancing Clinical Therapeutics Globally — a global network of experts conducting HIV research — has found that daily use of statins could reduce risk of cardiovascular disease in people living with HIV by 35 percent. This pivotal work was conceived by and led by Steven Grinspoon, HMS professor of medicine and director of the Metabolism Unit at Mass General Hospital.
While this offers a path toward managing HIV-related complications, Kuritzkes emphasizes that the ultimate quest of research efforts remains achieving sterilizing immunity through a vaccine that halts the virus in its tracks, preventing infection from taking hold in the first place.
The roadmap to a vaccine
With some 1.3 million new infections a year, a vaccine remains the best way to end the HIV epidemic, said Dan Barouch, the William Bosworth Castle Professor of Medicine at HMS and director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center.
“We should use all of our prevention and treatment tools, including education and pre-exposure prophylaxis with antiretroviral drugs, to prevent HIV, but to really end the epidemic, we need a vaccine,” Barouch said.
Despite great strides with PrEP, Barouch notes, it will only reach high-risk individuals, and as many as half of new HIV infections occur in people who are not designated as high risk. Thus, Barouch notes, even if PrEP were available for free and accessible to everyone in the world, which is far from reality, it would still invariably reach a ceiling of population efficacy.
Yet, after 40 years of effort, the HIV vaccine field is at a crossroads. Since the dawn of HIV research, there have been hundreds of attempts at vaccine design, and dozens have made it to early-stage clinical trials, but only five have been tested in large-scale clinical trials.
“There is a lot of exciting basic, preclinical, and early clinical research, but currently no vaccine candidate has a clear trajectory for advanced clinical development,” Barouch said.
Why?
First, the ability of the virus to shapeshift within the host and across the population. The virus mutates rapidly, resulting in an astonishing genetic diversity not seen with any other virus.
“With HIV, you are not targeting a single virus, you’re targeting millions of different viruses,” said Barouch.
Another problem is the fact that the virus integrates itself into the host genome quickly — within days following infection — then goes into hiding, establishing a latent reservoir that can reactivate at any time. This means that a vaccine needs to induce rapid immune response that counters viral maneuvers very rapidly. No other virus seeds reservoirs so quickly, and no other vaccine has been capable of inducing such rapid defense.
Finally, the virus is cloaked in an envelope of sugar molecules — or glycans — that render it largely impervious to antibodies. There are only three or four targets on HIV that render it vulnerable to antibodies. Thus, for antibodies to work, they must be hyperprecise to latch on to these hotspots in order to disrupt the viral shield. This, Barouch notes, may be one of the greatest hurdles to developing a potent enough vaccine.
Among the most recent efforts was a vaccine developed by Barouch and Johnson & Johnson that was tested in Africa and in South and North America. The approach used a so-called “mosaic” platform optimized using computational biology to target multiple strains of the virus.
The researchers used computer design to create a mosaic antigen in the lab. The trial, which concluded in 2021, showed the vaccine had great safety but low efficacy — around 14 percent. A vaccine needs to be at least 50 percent effective, but ideally 70 percent or more, Barouch noted, meaning that it would have to prevent at least seven out of 10 infections.
Despite the disappointing results, Barouch said, the findings helped refocus the field of HIV vaccine research on the importance of neutralizing antibodies — the types of immune proteins that are capable of disabling rather than merely recognizing the virus.
To that end, Barouch and team have redoubled their efforts to design vaccines that create precisely such broadly neutralizing antibody response as well as spark a robust T cell response, thus activating both major arms of the immune system.
Lessons from elite controllers
In the early 1990s, researchers noticed a tiny subset of HIV-infected patients who were living healthy and symptom free without medication. These patients, who came to be known as elite controllers, had undetectable viral levels in their bodies. Their immune systems were powerful enough to naturally keep the virus from replicating. Between 0.15 and 1.5 percent of HIV-infected individuals are estimated to be elite controllers.
“In these individuals, the immune system is able to suppress HIV replication,” said Yu, whose lab focuses on the molecular and cellular mechanisms behind this remarkable immune response, with the hope of harnessing these insights to develop new antiretroviral treatments for HIV. “And in a rare subgroup, the immune system may even eliminate all cells infected with replication-competent HIV, curing the infection entirely.”
When Gaurav Gaiha, then a first-year student in the Harvard-MIT Program in Health Sciences and Technology, learned about elite controllers, he was captivated by the concept of using insights from these unique individuals to develop an HIV vaccine.
At that time, a prevailing scientific theory was that elite controllers had an exceptionally powerful T cell response to HIV. However, when Gaiha began comparing the T cell responses in elite controllers to that of people living with progressive HIV, he discovered something surprising: While T cell function in elite controllers was important, there was another important piece to this biological riddle. Gaiha therefore shifted his focus and instead began to zero in on the specific regions of the virus that these T cells were targeting.
In a 2019 study, Gaiha, Walker, and colleagues applied network theory to tackle this question. They treated each amino acid in the viral proteins as a node in a network, allowing them to quantify how central each amino acid was to the protein’s function. Their findings offered a breakthrough: T cells in elite controllers consistently targeted critical regions of the virus protein network — areas that were essential for its survival and losing or mutating them would significantly hinder the virus’ ability to replicate.
“It’s similar to key players in a network,” said Gaiha, now an assistant professor of medicine at HMS and a principal investigator at the Ragon Institute of Mass General, MIT, and Harvard. “Key players keep the network connected, while others may be more on the periphery. If T cells target key player amino acids from these critical regions of viral proteins, you may have a chance to control the virus for a long period of time without therapy.”
These insights, Gaiha noted, have implications beyond HIV — they helped guide COVID-19 vaccine developments that stimulate T cells and induce a robust and long-lasting immune response.
Encouraged by promising results in humanized mice, Gaiha and Walker are now collaborating with two biotech companies to translate these insights into a viable HIV vaccine. The group’s viral vector-based vaccine candidate is set to enter a first in human clinical trial in Zimbabwe and South Africa in early 2025, while a second RNA-based vaccine trial is meant to begin in 2026 at Mass General.
“I am hopeful that we will see good outcomes from these initial vaccine trials,” said Gaiha. “But more importantly, I am looking forward to learning key lessons that will guide us, so we can continue to refine. We’re in this for the long haul.”
Ripple benefits beyond HIV
The search for a cure continues, but the sinuous 40-plus-year journey has fueled advances well beyond HIV.
For starters, many of the successes in the identification, testing, and treatment of SARS-CoV-2, the virus that ignited the COVID-19 pandemic, were built on knowledge and hard-earned experiences with HIV.
“Research on HIV really paved the way for the advances that were made with COVID, by laying the platforms for vaccine development that, in particular, the vectors that were used to generate immune responses, the mechanisms for rapid diagnostics, the understanding of viral pathogenesis — all were really contributed by work that had been done on HIV,” Walker said.
“If it wasn’t for the decades of HIV research, we would not have had the COVID-19 vaccines so rapidly.”
Dan Barouch, director of the Center for Virology and Vaccine Research, BIDMC
“If it wasn’t for the decades of HIV research, we would not have had the COVID-19 vaccines so rapidly,” Barouch said.
HIV research also equipped scientists with the tools and know-how to unravel viral structures and monitor the behavior of viruses inside their hosts. This work also led to the development of animal models that allow researchers to study how the body responds to vaccines and treatments and laid the foundation for the modern-day infrastructure needed to conduct clinical trials.
HIV research has catalyzed understanding of immune system function in myriad ways. For example, recent advances in gene therapy and CAR T cells were heavily influenced by research conducted in HIV infection.
“Fundamental mechanisms of how the immune system can recognize, engage, and target virally infected cells were first discovered in the context of HIV infection, and a lot of this progress has subsequently been translated to alternative disease contexts,” said HIV researcher Xu Yu, professor of medicine at HMS and a principal investigator at the Ragon Institute of Mass General, MIT, and Harvard.
For example, gene therapy uses lentiviruses as vectors to deliver therapeutic genes into the target cells.
“These lentiviruses are very similar to HIV, and a deeper understanding of HIV allowed researchers to use lentiviruses for therapeutic gene transfer,” Yu said.
HIV research also helped advanced the field of CAR T-cell therapy, which uses genetically engineered immune cells for the treatment of blood cancers. One of the first CAR T-cell studies was done in the context of treating HIV infection, more than 20 years ago.
“Experience gained with CAR T cells in this setting was instrumental in advancing them for oncologic indications,” Yu said.
Campus & Community
Not so much the form, but the function
Gund Hall on Quincy Street.Photos by Jon Ratner
Christina Pazzanese
Harvard Staff Writer
November 27, 2024
5 min read
Gund Hall may look the same but a major renovation has improved its energy efficiency and accessibility. (And, now, hopefully, the roof will stop leaking.)
Gund Hall, it is safe to say, was overdue for an updat
Gund Hall may look the same but a major renovation has improved its energy efficiency and accessibility. (And, now, hopefully, the roof will stop leaking.)
Gund Hall, it is safe to say, was overdue for an update after weathering 50 Cambridge winters.
The iconic Quincy Street home of Harvard Graduate School of Design (GSD) is open after a major renovation this year, its most significant since the building opened in 1972. While the changes may not be readily apparent, the need was.
The hall’s concrete-and-glass stepped exterior, which encloses GSD’s beloved five-story, central studio area known as “the trays,” had badly deteriorated over the years, allowing moisture and cold air to seep in, and heat to escape. The space was so inefficient, it consumed nearly half of the building’s total energy. Before rainstorms, students covered their desks with tarps.
“The main purpose of this work is to get rid of the leaks once and for all. This building, for the 52 years it has been open, has always leaked. When it rains hard, you see the buckets everywhere,” said David Fixler, a lecturer in urban planning and design at GSD who chairs the faculty building committee, which has been advising on this first phase of what will be a multiyear project.
Other improvements include boosting the amount of natural light coming into the trays and making the adjacent outdoor terraces wheelchair-accessible for the first time.
For decades, the building’s unique design, as well as its historic and educational importance to GSD, have presented major obstacles to undertaking any substantive restoration that would fix these persistent problems without compromising the look and feel of the original design by Australian architect John Andrews, March. ’58.
The five-story, central studio area known as “the trays.” Nearly all of the original windows were badly degraded and couldn’t be salvaged.
Gund Hall Project Fact Sheet
15,475
Square feet of studio tray glazing area
1,617
Panels of glass
160,830
Total square footage of Gund Hall, excluding terraces
28%
Amount of floor area taken up by studio trays
46%
Building’s total energy consumption attributed to studio trays
“When John Andrews was originally tasked to design a new facility for the Departments of Architecture, Landscape Architecture, and Urban Planning and Design, he surprised his clients with a unique building that was at once solid and transparent and that prioritized the student body, united within an enormous, light-filled, single space,” Sarah M. Whiting, dean and Josep Lluis Sert Professor of Architecture at GSD, said in a statement. “Though much has changed since Gund Hall first opened in 1972, the careful rehabilitation of the structure underscores the school’s commitment to this same priority: our students.”
Gund, like other examples of mid-century Brutalist architecture, was constructed before the 1973 global “oil shock” and widespread awareness of climate change. It features large surfaces of exposed concrete, many windows, and is not well-insulated, all of which make it less than well suited to the harsh climate of New England.
“Philosophically, one of the compelling things about brutalism is the structure is the building. What you see is what it is. There’s nothing hidden,” said Fixler, an architect who specializes in mid-20th century building conservation. That means “sometimes they fail spectacularly, and they’re hard to fix.”
Nearly all of the original windows were badly degraded and couldn’t be salvaged. Above, clerestory windows on the roof were replaced with triple-glazed windows.
The curtain walls on each end of the building now have windows made from custom vacuum-insulated glass, a state-of-the-art material not widely used in North America. They provide energy efficiency and noise reduction comparable to traditional triple-glazed windows without the bulk, allowing the new windows to hew very closely to the original window profiles and glass sizes, while delivering two to four times better energy performance than standard glass. They will yield future savings in both carbon and dollars spent on utilities.
Gund Hall features large surfaces of exposed concrete and numerous windows.
The project takes an aging facade that “had the problems of its time to a facade that is the best-performing glazing system anywhere,” said project architect George Gard, MAUD ’14, of Bruner/Cott Architects. The firm has restored other mid-century buildings at Harvard, including Smith Campus Center and Peabody Terrace.
With so many Brutalist-era buildings around the country now confronting similar challenges because of age, the School hopes the project serves as a model for others, by identifying innovative technology, techniques, and materials and helping define best practices.
“We see a lot of future potential as it becomes more common. And we hope that, this project being a high-profile building on Harvard’s campus, can be part of a growing acceptance of this technology,” said Gard.
Given the project’s unique complexity, Fixler, a conservation architect for many decades, has been incorporating the renovation into his teaching.
“What I find heartening is that [among] the students, there’s a growing understanding that it’s a really responsible thing to do to recycle old buildings, whether you like them or not, and to use that opportunity to test new ideas to make them more resilient, make them more sustainable,” he said.
Not everyone appreciates Brutalist behemoths like Gund Hall or Boston City Hall, often called one of the country’s ugliest buildings, or thinks they’re worth preserving.
“One of the biggest challenges, frankly, is getting people to understand why these are good, interesting buildings, and getting people to love them — because so many people hate them,” he said.
“There are a lot of people, especially younger people of the generation that I’m teaching now and my kids, [who] think these buildings are cool. But an awful lot of people of my generation just don’t.”
Science & Tech
Ever wonder why your dog does this?
Study decodes neural mechanism that causes hairy mammals to shake their fur when wet
Alvin Powell
Harvard Staff Writer
November 26, 2024
6 min read
It’s a regular occurrence when taking our canine pals for drizzly walks and summer swims. But until recently, the biology behind the water-flinging, human-drenching, muzzle-distorting “we
Study decodes neural mechanism that causes hairy mammals to shake their fur when wet
Alvin Powell
Harvard Staff Writer
6 min read
It’s a regular occurrence when taking our canine pals for drizzly walks and summer swims. But until recently, the biology behind the water-flinging, human-drenching, muzzle-distorting “wet dog shake” has mystified scientists working to decode the sense of touch.
Last month, researchers in the lab of David Ginty, the Edward R. and Anne G. Lefler Professor of Neurobiology and chair of Harvard Medical School’s Neurobiology Department, reported in work published in the journal Science that they’d used cutting-edge techniques to track sensory signals that underlie wet dog shakes from receptors on the skin to a part of the brain called the parabrachial nucleus.
Using tools — many developed in the Ginty lab — that allow researchers to isolate and trace single neurons and stimulate or block them using light, the researchers determined that the shaking behavior can be evoked by activating a class of sensory neurons called C-LTMRs and, conversely, the number of wet dog shakes evoked by mechanical stimuli decreases when C-LTMRs and the parabrachial nucleus are muted.
The researchers determined that the shaking behavior can be evoked by activating a class of sensory neurons called C-LTMRs.
Though unseen in humans, the motion is universal among fur-bearing mammals, serving as something of an early warning system that insects, dirt, water, and other substances are about to come into contact with the skin. Occurring in everything from grizzly bears to dogs and cats to lab mice, the response is innate, Ginty said, meaning that, though reflexive, it can be controlled by the animal. In humans, Ginty compared it to feeling a bug landing on your arm: You may jerk your arm or flick at it with your other hand with little thought, but it can be controlled if desired. In Ginty’s lab, researchers used droplets of sunflower oil applied to the upper back to trigger the response in mice who’d been genetically engineered so that specific neurons could be stimulated or blocked using light.
“One thing we’ve done over the last 15 to 20 years is generate genetic tools that allow us to study each of the sensory neurons that associate with the skin in isolation and that’s been incredibly powerful,” Ginty said.
The skin has approximately 20 different types of sensory receptors, including those that detect hot, cold, itch, and touch. Twelve or so receptors detect different types of touch, from a quick stab of pain to vibration to steady pressure to a soft caress. The signal triggering the “wet dog shake” starts in C-LTMRs, or C-fiber low threshold mechanoreceptors, which wrap around the base of a hair follicle. The receptor is one of the body’s most sensitive and can pick up the slightest movement of the hair or a depression of the skin around the hair’s base.
From the receptor, the signal travels along nerve cells into the spine, where it joins with the spinal cord. The signals then emerge from the spinal cord and travel to the brain stem and the parabrachial nucleus. Beyond enhancing our understanding of a basic and familiar mammalian behavior, Ginty said that the techniques developed have allowed researchers to overcome a major hurdle — understanding what’s going on inside the spinal cord.
“We understand the logic of organization of the neural circuitry that underlies visual information processing and sound information processing,” said Ginty, whose lab has been focused on unravelling the neurobiology of touch for decades. “For touch — for somatosensory information processing — we’re kind of in a black box trying to understand it because it’s been so challenging to access and record neural activity in the spinal cord.”
Though they’ve tracked the signal to a specific location in the brain, Ginty said many questions remain. An important one is understanding whether the pathway they identified accounts for all the wet dog shake response or, given the limitations of their functional manipulations, if there’s more going on than they were able to see.
“We’re struggling to answer that question, because the tools we typically use are rarely 100 percent effective in blocking one of these steps,” Ginty said. “So, you never know if a residual 10 percent underlies the remaining behavior or if there’s another pathway or another cell type that you’re missing. In this case, I guess it’s the latter, but we can’t be sure.”
Another important question in the work, supported by the National Institutes of Health and the Lefler Center for the Study of Neurodegenerative Disorders, is why, if C-LTMR receptors are located all over the body, do only those on the upper middle back trigger the response?
“It’s a very exciting time to understand brain-body physiology: how the body is represented in the brain and how the brain, in turn, controls organ systems of the body.”
David Ginty
From a behavioral standpoint, the answer is clear — that part of the body is out of reach of claws and paws and hooves for swatting or scratching — but that doesn’t explain how nerve signals from that part of the body trigger the wet dog shake while other signals that begin in the same type of receptor and go to the same part of the brain do not. Perhaps, Ginty said, the signals emanating from the nerves originating on the upper middle back propagate to unique regions of the parabrachial nucleus from those originating elsewhere on the body. Another possibility, he said, is that the signal from the upper back is somehow amplified in the spinal cord before reaching the brain.
Though Ginty is a dog lover, he said the work began not out of an appreciation for dogs but by accident. Dawei Zhang, then a graduate student in Ginty’s lab, was using optical tools to activate the then-mysterious pathway beginning with C-LTMR and noticed that every time he did, the mouse would give itself a shake. When Zhang and Ginty saw the reaction, they immediately realized what it was.
“It’s a very exciting time to understand brain-body physiology: how the body is represented in the brain and how the brain, in turn, controls organ systems of the body,” Ginty said. “Some of the new tools coming online are really powerful for helping us unravel these circuits.”
Polaroid gave her a shot. She helped revolutionize photography.
HBS Communications
4 min read
Meroë Morse — focus of Baker Library exhibition — led company’s researchers during innovative era
Meroë Morse had no formal background in business or science when she started at Polaroid in 1945, but within a few years she rose to become manager of black-and-white photographic research and later to director of special photographic research, a notable achievement for a woman in the 1950s and ’60s.
A new exhibition at the Business School’s Baker Library is putting the focus on Morse and her contributions to the development of instant photography — launched commercially by Polaroid in 1948. The collection, “From Concept to Product: Meroë Morse and Polaroid’s Culture of Art and Innovation, 1945–1969,” on view in Baker’s north lobby through April 18, draws on the library’s extensive holdings of the Polaroid Corporation Collection.
“The function of industry is not just the making of goods, the function of industry is the development of people.”
-Edwin Land, the founder of Polaroid
A culture of innovation
Edwin H. Land, Polaroid’s founder, cultivated a creative culture within his research and manufacturing enterprise, building an interdisciplinary community devoted to technical and artistic excellence.
Morse, an art history graduate of Smith College, found exceptional opportunities for women in the post-war era at Polaroid. She oversaw round-the-clock shifts of researchers conducting thousands of experiments in the company’s Cambridge laboratory, and met increasing demands for new Polaroid films as the popularity of instant photography soared.
Morse’s affable and commanding presence among her male colleagues.
Instant photography is launched
The first instant film and camera sold for $1.75 and $89.75 respectively on Nov. 26, 1948, in Boston’s Jordan Marsh department store. The camera measured 10½ by 4½ by 2½ inches and weighed four pounds, two ounces. It featured an optical foldout viewfinder, a three-element 135-mm f/11 lens, and shutter speeds from 1/8 to 1/60 of a second. All 56 cameras sold out that day.
Morse holds a hand-made wheel containing names of some of the developing chemicals used in instant photography.
Early Polaroid test photograph of Edwin Land in November 1945.
The first Polaroid film, Type 40, produced sepia-toned prints with a limited tonal range.
Children pose for a test photo.
In 1950, the company introduced black-and-white film Type 41.
Research in black and white
In 1948, Morse became the laboratory supervisor responsible for photographic materials. The earliest Polaroid film, Type 40, produced sepia-toned prints that had limited tonal range. Morse and her lab looked to produce black-and-white images that exhibited greater detail and a color palette more familiar and appealing to consumers. In 1950, after two years of intensive work, the company introduced black-and-white film Type 41. The film produced prints that exhibited finer detail and, as U.S. Camera enthused, created “pictures-in-a-minute of exceptional tonal values.” The Detroit Free Press reported that Land credited Morse with “valuable assistance in research that led to the new film.”
Meroë Morse poses for Polaroid test photos.
Ansel Adams and Polaroid
Morse also served as chief liaison to Ansel Adams, the renowned landscape photographer. A principal consultant for Polaroid from 1948 until his death in 1984, Adams tested the company’s prototype cameras and film. He reviewed technical and design aspects of Polaroid prototypes, from the wording of instruction manuals to the tonal values of finished prints.
The exhibition was organized by Baker Library Special Collections and Archives, with support from the de Gaspé Beaubien Family Endowment. This text is drawn from the exhibition catalog.Find more information at the Baker Library website.
Passing through an autumn campus at Harvard University.Photos by Stephanie Mitchell/Harvard Staff Photographer
Campus & Community
Updating their 3-word bios
Stephanie Mitchell
Harvard Staff Photographer
November 25, 2024
8 min read
Juniors who talked to us when they first arrived here — and again as sophomores — reflect on how they’ve changed
Gazette photographer Stephanie Mitchell h
Juniors who talked to us when they first arrived here — and again as sophomores — reflect on how they’ve changed
Gazette photographer Stephanie Mitchell has been conducting a bit of an experiment inspired by her own college years — specifically the address by Nora Ephron to Wellesley’s Class of 1996 expressing, “You are not going to be you, fixed and immutable you, forever.” She met with a group of Harvard students during their first year and sophomore year, photographed them, and asked them to describe themselves in three words. The students, now juniors, participated in the exercise once again. The three words they chose appear below in gray (2022), dark gray (2023), and black (2024).
Free. Independent. Friendly.
Independent. Free. Possibility.
Free. Independent. Creativity.
First Year
Sophomore Year
Junior Year
Sofia Chavez
Currier House
When we first spoke to Chavez in 2022, the student from Hidalgo, Mexico, noted that she was “learning how to be independent for the first time, leaving home and my country.”
This year, she said: “I’m growing. I’m an adult. I have the freedom of choosing my own path, making decisions, making mistakes, and learning from them.”
In all three of her interviews, Chavez described herself as “free” and independent.” She added a new descriptor this year: creativity. “It gives you the tools to solve problems, not only academically, but in your life.”
As a first-year, she listed women’s and gender studies and sociology as academic interests. By the fall of her sophomore year, she was leaning toward a government concentration in the law and justice track with a secondary in economics. Chavez has since declared a government concentration with a language citation in French. She is considering a senior thesis in political theory and a career in law.
“As a perfectionist or overachiever, you always want to have things in control,” said Chavez, but lately she is happier because “I don’t think about those expectations anymore, only my own.”
God-loving. Adventurous. Passionate.
God-loving. Adventurous. Kind.
God-loving. Grateful. Composed.
First Year
Sophomore Year
Junior Year
Bradley Chinhara
Lowell House
Two years ago, Zimbabwe native Chinhara characterized himself as an “adventurous” person with “diverse interests,” from electrical engineering to rugby to playing the marimba. He credited Christianity and love of family as guiding forces.
“I still pray every day. I still love my religion,” said Chinhara. He’s added two new descriptors this year.
“Grateful, because I wake up every day, and I realize that I go to Harvard, which was one of my biggest dreams growing up. … Grateful for my mom. She passed away, but she lived a beautiful life. … And then composed, because I’m a junior now. I know how things work. I’ve made mistakes, and I’ve learned from them. I’m now at a point where I know what I want. I know how to pursue it.”
Chinhara’s interest in computer science hasn’t wavered as he tilts toward tech entrepreneurship and product management. In 2023, he launched a software development startup. He said he will declare a secondary in economics and is considering business school.
Last spring, he “started reaching out more, talking to more people, going to office hours.”
“It dramatically improved my academic life, my social life, my mental health.”
Fun. Kind. Excited.
Grateful. Motivated. Hopeful.
Energized. Grateful. Inspired.
First Year
Sophomore Year
Junior Year
Myra Bhathena
Pforzheimer House
“Building relationships is the most important thing to me,” said Bhathena in her first-year interview. That theme continues today. She feels energized, she said, “reflecting on the people who have gotten me here.”
“It brings me back to my family — my grandparents, my parents, my siblings. I was lucky to spend the end of the summer with a lot of them, and they always ground me.”
Bhathena has completed many foundational requirements for her economics concentration and is turning to her secondary in global health and health policy. Interning at Boston Children’s Hospital doing research this past summer has only reaffirmed her pre-med track. “I am really excited to dedicate my career to medicine and to caring for people.”
She has moved into mentorship roles in clubs and the classroom, for example serving as a Teaching Fellow for EC10. “I love teaching, and I’m excited to meet new freshmen in the class who are just as nervous and scared as I was.”
This year, “I am a more balanced person,” Bhathena said. “Time has given me more freedom to just be myself and take some deep breaths and enjoy my last two years here.”
Friendly. Excitable. Ambitious.
Approachable. Adaptable. Vibrant.
Evolving. Ambitious. Present.
First Year
Sophomore Year
Junior Year
Dara Omoloja
Leverett House
Omoloja spent the summer back home in Wisconsin. “I had a lot of time to think and contemplate my priorities. There’s so much I need to do and that I want to do in this life.”
In her first Gazette interview Omoloja said she was most looking forward to “immense personal discovery that everyone mentions when thinking about college.”
Now a junior cognizant of how quickly time is passing, she said, “In the past, I spent so much time looking down, be that at my phone, or as I walk, looking at the floor, because I’m thinking about how all these people are seeing me. But now, I really want to pay attention, to be present. Every time I look around, I think, ‘Wow, this world is so pretty, and I want to just take that in more.’”
Reflecting on last year, Omoloja said, “I learned to advocate for myself more. … My biggest lesson was although it is important to show kindness and to have community, it shouldn’t go at the expense of your personal comfort and happiness. … I’m more comfortable in my identity this year. I’m very happy to be me.”
“Ambitious,” a word she used to define herself in 2022, re-emerged as she studies for the MCAT and takes the courses “Medicine and Health in America” and “Therapeutic Rationalities,” concrete steps toward becoming a doctor.
Adventurous. Ambitious. Authentic.
Excited. Fun. Adventurous.
Excited. Relaxed. Melancholy.
First Year
Sophomore Year
Junior Year
Austin Wang
Lowell House
Wang describes himself as both excited and relaxed this year. “I think believing in yourself and having confidence is really important,” and when things become hectic “it’s good to be relaxed and Zen.”
Rejuvenated from a summer of seeing friends and family, doing genetic computational research at the Medical School, and volunteering at the Harvard Square Homeless Shelter, Wang also feels a bit melancholic.
“I looked down at my Pset, and I look up, and it’s already junior year. It went by really quickly … I’m looking forward to the second half.”
Since his last interview, the Canada native has declared his concentration in chemical and physical biology with a secondary in computer science and has continued to find ways to break out of his comfort zone, a goal he emphasized in previous years.
Ringing the Lowell House bells every Sunday has been “super fun.” He shares the recruitment joke for the bells, known for waking up students at the bright hour of 1 p.m. on Sundays: “If you feel like you’re too well liked, feel free to join!”
Creative. Passionate. Fun.
Enthusiastic. Creative/Artistic. Natural.
Creative. Mellow. Open.
First Year
Sophomore Year
Junior Year
Nali Gone
Eliot House
Creativity has been a constant for Gone over the past three years. “It’s a great way for me to engage with the world and understand what people think and feel.”
This year, “I’m not as worried about what’s going to happen. I’m just living in the moment. I am really trying to put myself out there and try new things. Now is such a formative time in my life.”
Gone has declared a concentration in women, gender, and sexuality with a secondary in psychology, and is currently taking a history class about the relationship between guns, property, and power, as well as a First Amendment seminar. “I’m in my amendment era, one might say.”
Last year Gone helped stage-manage for the Harvard-Radcliffe Dramatic Club musical “Jekyll and Hyde” and the musical comedy “The 25th Annual Putnam County Spelling Bee,” and continues this year with the musical “Pippin.”
A key lesson from sophomore year: how to find balance and take breaks between time commitments.
Excited. Determined. Outgoing
Excited. Passionate. Ambitious.
Growth. Excited. Passionate.
First Year
Sophomore Year
Junior Year
Riley Flynn
Eliot House
Softball continues to be a focus for Flynn, a rise ball and curveball pitcher who was named Ivy League Rookie of the Year in 2023. While athletics can be time-consuming, she enjoys the camaraderie while traveling the country with her teammates.
Last season, Flynn underwent elbow surgery. “I’m finding my way, working through rehab, and my team has been great through all of that, supporting me and helping me. I should be able to play in the spring.”
What else has changed? “My first years were definitely more about exploring, and this year, I have found things that I am passionate about, whether it’s making friends, playing sports, what I’m studying, and I’m definitely going to go deeper into that in the next two years.”
She’s delving into her concentration in human developmental and regenerative biology with a neuroscience secondary, taking courses in organic chemistry and psychopharmacology.
“I feel that I’ve found my place here and now it’s more about growing in order to continue finding people and places that I love.”
From left top row Aneesh Muppidi, Sofia Corona, Thomas Barone, Laura Wegner; second row, Matthew Anzarouth, Ayush Noori, Lena Ashooh, Shahmir Aziz.Photos by Stephanie Mitchell and Niles Singer/Harvard Staff Photographers; photo illustration by Liz Zonarich/Harvard Staff
Campus & Community
Rhodes scholars share their Oxford ambitions
Anne J. Manning and Eileen O’Grady
Harvard Staff Writers
November 22, 2024
8 students to pursue social, political, computational sciences
Whether examining animal ethics, combating AI bias, or weighing the values essential to a functioning democracy, Harvard’s newest Rhodes Scholars have made their mark across a wide expanse of disciplines. These eight seniors, representing four countries and several U.S. states, will continue their academic pursuits at the University of Oxford next year. They shared their plans, accomplishments, and what it was like to receive the news of their award.
Matthew Anzarouth.
Niles Singer/Harvard Staff Photographer
Matthew Anzarouth
Montreal, Canada
Concentration: Social studies
Matthew Anzarouth was at home with family in Montreal when he got the phone call that he had won a Rhodes Scholarship for Canada. Anzarouth was one of two recipients from the region that includes Ontario, Quebec, and the Maritime provinces.
“I felt a mix of shock, excitement, and profound gratitude,” Anzarouth said. “This opportunity is an extraordinary privilege, and I’m really keen to make the most of it.”
Anzarouth is currently writing a thesis on Canadian federalism and multiculturalism, with an emphasis on language policy in Quebec and Indigenous self-determination. The Mather House resident is using political theory to examine the challenge of reconciling universal individual rights with group rights specific to Canada’s national minorities.
“I’m using political theory as a way of understanding — and hopefully better resolving — the challenge of coexistence in a culturally diverse federation,” Anzarouth said. “The thesis work has helped me stay engaged with my country’s politics and reflect on how I want to contribute.”
At Oxford, he hopes to continue his studies of political theory, focusing on questions of how to balance competing claims for cultural preservation and how to balance power between legislative and judicial bodies of government. He hopes to eventually attend law school.
Lena Ashooh.
Stephanie Mitchell/Harvard Staff Photographer
Lena Ashooh
Shelburne, Vermont
Concentration: Special concentration in animal studies
The summer after her first year on campus, Lena Ashooh worked as a research assistant in Puerto Rico, studying the impacts of natural disaster and trauma on the behavior of a colony of free-ranging macaque monkeys. It was a pivotal moment for the Kirkland House resident, who said it felt like observing an “extremely sophisticated society of individuals.”
“That was where I initially had the idea that, were the conditions that animals are in to change completely, they might behave in ways that we never imagined,” Ashooh said. “This led me, in philosophy, to working out how we might wrong animals in the beliefs we have about them and to be interested in how we’re managing land, the decisions we’re making about who has access to land, and who should be involved in the decision-making process.”
Ashooh designed a special concentration in animal studies, combining political philosophy, government, and animal psychology. She is an undergraduate fellow at the Edmond and Lily Safra Center for Ethics, has written for the Harvard Review of Philosophy, and co-founded Harvard College Animal Advocates. Off-campus, she works as a lab manager in animal cognition scientist Irene Pepperberg’s parrot lab at Boston University.
“I say that to study animal studies is to study social injustice and gives us a new way of understanding how oppression and violence occurs, and how moral complacency and inaction occur,” said Ashooh, who is planning to eventually attend law school. “One of the key questions that animal studies allows us to address is: How is it that people can be led to look at suffering and decide not to act on it?”
Ashooh hopes to study philosophy next year, focusing on the question of what it means to treat and respect an animal as an individual.
Shahmir Aziz.
Stephanie Mitchell/Harvard Staff Photographer
Shahmir Aziz
Lahore, Pakistan
Concentration: Biomedical engineering and mathematics, secondary in computer science, language citation in French
As an undergraduate researcher in different Harvard labs, Shahmir Aziz has analyzed the impact of physical exertion on the glycolytic levels of diabetes patients and has investigated nano-lipids as potential drug delivery vesicles. As an intern at Novo Nordisk, he has focused on optimization of drug-delivery processes.
He wants to keep working on the cutting edges of biotechnology, and he wants to help others do so as well, in his native Pakistan.
“In the long run, I hope to help start a culture of startups and biotech in Pakistan, so that students and other innovators can grow out their ideas,” said the Adams House resident named one of two Rhodes Scholars for Pakistan.
A first-year course in quantitative physiology taught by Linsey Moyer solidified Aziz’ chosen field of study. He also took courses in government and political philosophy, feeding an equal passion for international relations.
At Oxford, Aziz plans to pursue a master’s in bioengineering, followed by a second degree in diplomacy and global governance — arenas in which he’s also made meaningful contributions on campus.
A member of the leadership team of Harvard’s International Relations Council, Aziz helped the University’s Model United Nations team win two major intercollegiate competitions. “The opportunity I have cherished most at Harvard has been to interact with students from all extremes and opposites of background, pursuing all nature of subjects, and dreaming all ranges of noble dreams,” Aziz wrote in his scholarship application.
Some of those interactions have come in his four years playing Harvard Club Tennis, as a sports editor with The Harvard Crimson, and as a course assistant in the Department of Mathematics.
Thomas Barone.
Niles Singer/Harvard Staff Photographer
Tommy Barone
Little Falls, New Jersey
Concentration: Social studies
Tommy Barone wants to understand what people believe, and why.
Barone currently is studying what he calls a “crisis of liberalism,” or the philosophical values essential to healthy democracy. In particular he’s interested in how best to understand the beliefs of people engaging in illiberalism in democratic societies.
“It’s so easy to create a narrative about why something important or worrying or disruptive in society is happening that serves your ends,” Barone said. “I think it’s a civic obligation that we listen to what people have to say and try to understand them. If you are trying to theorize something that involves people without speaking and listening to the people who are part of that phenomenon, you’re going to be missing something.”
Barone said that when he learned he had been named a Rhodes Scholar, all he could do was start “breathing heavily.”
“I didn’t cry until I called my parents,” Barone recalled. “Then I cried. Then I had to get it together to talk to the judges afterward.”
The Currier House resident, who hopes to pursue journalism in the future, is co-chair for the editorial board at The Crimson. Their coverage won first place for editorial writing in collegiate journalism in the Society of Professional Journalists’ 2023 Mark of Excellence Awards.
“I’ve had the unique challenge, but also the really educational, enriching experience, of being tasked with bringing people together to have difficult discussions in one of the most challenging years on campus in decades,” said Barone, who plans to study history at Oxford. “I’ve had the privilege to publish a really broad diversity of perspectives on a range of important issues on campus.”
Sofia Corona.
Stephanie Mitchell/Harvard Staff Photographer
Sofia Corona
Miami, Florida, and Pereira, Colombia
Concentration: Applied mathematics and economics, secondary in government
From watching her mother commute several hours a day for work in Maryland to biking throughout her community, Sofia Corona learned early on that how people move is fundamental to the human experience.
Helping people get where they need to go — within cities, towns, and systems that benefit all — has become her life’s work. “I’m interested in how communities are engaged in infrastructure planning, especially when the benefits of that infrastructure are collective and widespread, but the burdens are localized,” said Corona, a Currier House resident graduating in December.
Corona, who hopes to work in the transportation sector, thinks seismic shifts toward sustainable modes of transportation are possible. “At the same time, our transportation networks are often superimposed on inherited, segregated landscapes, both racially and socioeconomically,” she said. “We can’t be agnostic to that.”
At Oxford, Corona’s master’s coursework will contextualize mobility systems within broader economic development and sustainability frameworks. At Harvard, she worked in the Allen Lab for Democracy Renovation, conducting research on inclusive decision-making in renewable energy projects. She also spent time in the MIT Transit Lab. Her professional experience includes internships at Uber, BMW, the U.S. Department of Transportation, and McKinsey & Co.
Her interests have taken her all over the world, from working on carbon dioxide pricing for the Chilean Ministry of Finance to collaborating with researchers at the Technical University of Munich on a tool that advises local transit agencies.
The Colombian American was a walk-on on Harvard’s varsity sailing team and is an avid mountaineer with the summits of Denali and Kilimanjaro among her feats, and she has run the Boston, New York, and Berlin marathons. Among her most cherished moments at Harvard have been as a dog-walker to Currier House dogs Huckleberry and Ari.
Aneesh Muppidi.
Niles Singer/Harvard Staff Photographer
Aneesh Muppidi
Schenectady, New York
Concentration: Computer science and neuroscience, concurrent master’s in computer science
Waiting in a room with other Rhodes Scholar finalists, Aneesh Muppidi did a homework problem set and chatted about South Asian politics, having already made peace with not winning.
“In my head I thought, ‘This has been an amazing process, but now it’s time to go back to the real world,’” the Lowell House resident said.
Then, he heard his name.
“I called my little brother first,” he said, followed by his parents and two best friends.
Muppidi has spent time mulling the question Alan Turing famously posed in 1950: Can machines think? He’s come to believe that understanding human intelligence — and computationally scaling up that intelligence — can solve some of the world’s biggest problems, such as diagnosing complex medical conditions or giving personalized tutors to every child in every classroom.
At Harvard, he’s immersed himself in the power and promise of artificial intelligence through projects on deep reinforcement learning in Assistant Professor Heng Yang’s Computational Robotics Lab; particle filter machine learning algorithms with the Fiete Lab at MIT; and autonomous agent detection with Professor Sam Gershman’s Computational Cognitive Neuroscience Lab.
Outside the lab, Muppidi is equally passionate about AI policy and ethics. Ensuring technologies are developed safely is a cornerstone of Muppidi’s research, which he plans to continue while pursuing master’s coursework in computer science and public policy at Oxford.
Muppidi served as president of Harvard Dharma and as president of the Harvard Computational Neuroscience Undergraduate Society. He includes among his mentors Sanskrit instructor Nell Shapiro Hawley, now at Vassar College, with whom he took two years of the ancient language of India. “How she taught had a very beautiful effect on my life, in the sense that I was able to get closer to my spiritual identity, who I am as a person, and what I believe in.”
Ayush Noori.
Stephanie Mitchell/Harvard Staff Photographer
Ayush Noori
Bellevue, Washington
Concentration: Computer science and neuroscience, concurrent master’s in computer science
When Ayush Noori was 7, his grandmother, Munira Brooks, was diagnosed with progressive supranuclear palsy, a rare neurodegenerative disease that slowly robbed her of the ability to speak, move, or breathe. Assisting in her care and witnessing her long struggle inspired Noori to pursue science and medicine. “My mission is to give people with neurological disease more time with their loved ones,” said Noori.
Noori has championed this mission for nearly a decade. Since the age of 12, working or volunteering in various labs, he has conducted research at the intersection of neuroscience, artificial intelligence, and precision medicine, seeking to develop new AI-enabled diagnostic and treatment options for patients with neurological disorders.
As an undergraduate, Noori has authored 25 peer-reviewed publications — including seven as first author — in scientific journals including Cell, Nature Neuroscience, Nature Machine Intelligence, Nature Aging, Alzheimer’s & Dementia, and NBD, and his work has been featured at more than a dozen international conferences. He has been advised by professors including Marinka Zitnik at Harvard Medical School; George Church at the Wyss Institute for Biologically Inspired Materials; and Sudeshna Das, Alberto Serrano-Pozo, and Bradley T. Hyman in the Department of Neurology at Massachusetts General Hospital. He plans to do graduate study in clinical neurosciences at Oxford next year.
The recipient of more than a dozen fellowships at Harvard and a Roberts Family Fellow at Harvard Business School, the Goldwater Scholar and Adams House resident is also devoted to teaching and mentorship as co-founder of the Harvard Undergraduate OpenBio Laboratory and as a peer adviser at Harvard College.
“I have an immense debt of gratitude toward Harvard because I’ve studied and trained here since I was a teenager,” he said. “The College, SEAS, MGH, and Harvard Medical School have enabled me to contribute to the global fight against neurological disease and given me hope for a healthier future, for my loved ones, and for the world.”
Laura Wegner.
Photo courtesy of Laura Wegner
Laura Wegner
Walsrode, Germany
Concentration: Economics, secondary in computer science
Laura Wegner, Currier House resident and Germany Rhodes Scholarship recipient, wants to address patients’ fragmented medical records and revolutionize healthcare technology to improve patient outcomes.
It’s a cause driven by personal experience. While in high school, Wegner, formerly a competitive swimmer, had to undergo surgery for a knee injury. Doctors used the “wrong surgical method,” Wegner said, due to not having access to her full medical history, including information about a pre-existing health condition, leaving her unable to continue swimming.
“That was a personal experience where I thought, ‘Wow, parts of my patient data are stored in so many different places, and I wish they were together somehow.’”
To improve experiences for future patients, Wegner co-founded the startup Mii in 2022, a patient healthcare passport that securely stores patient data so patients can bring their medical history from doctor to doctor, around the world.
Wegner has taken Harvard courses in health economics, privacy and technology, and entrepreneurship, and has worked as a fellow with the Lemann Program on Creativity and Entrepreneurship. Eager for global perspectives, Wegner has studied digital healthcare systems in the U.S., Germany, and Australia, and she is writing her thesis on systems in Estonia and Lithuania.
Looking forward to improving her technical skills at Oxford with the hope of continuing her work in healthcare technology, Wegner says she loves both the creative and technical sides of entrepreneurship.
“It’s just about having an idea and then immediately being able to build a prototype, test it out, and see where it goes. It’s an amazing opportunity to bring any idea to life, and hopefully have it improve people’s lives.”
Nation & World
What Trump got right
Setti Warren and Kellyanne Conway.Photos by Niles Singer/Harvard Staff Photographer
Christina Pazzanese
Harvard Staff Writer
November 21, 2024
3 min read
Kellyanne Conway, president-elect’s 2016 campaign manager and former senior adviser, discusses recent election, what comes next
The Democrats got it wrong.
It wasn’t threats to national securit
Kellyanne Conway, president-elect’s 2016 campaign manager and former senior adviser, discusses recent election, what comes next
The Democrats got it wrong.
It wasn’t threats to national security or democracy, and it wasn’t the U.S. Supreme Court’s undoing of Roe v. Wade. What voters cared most about this election was “safety, affordability, fairness, and education,” said Republican operative Kellyanne Conway during a sometimes testy 90-minute talk at the JFK Jr. Forum about the 2024 election and what to expect from the incoming Trump administration.
That’s why ads and other messaging about crime, inflation, immigration, student loan forgiveness, and school choice proved so effective in the campaigns of President-elect Donald Trump and several other Republican candidates, she told Setti Warren, director of the Institute of Politics at Harvard Kennedy School.
Trump won by running up the numbers of voters already predisposed to vote for him and “peeling off” some support among “core Democratic” Party constituencies, including African Americans, Hispanic Americans, union households, Jewish, and younger voters, improving on his own 2016 and 2020 numbers, said Conway, who managed the final months of Trump’s 2016 campaign and served as an adviser during his first term.
Conway said she thinks Democrats underestimated how motivating the issue of K-12 education was to many across the political spectrum, particularly women, who did not support Harris as robustly as they had Presidents Joe Biden and Barack Obama.
Trump was seen as “authentic” and a proven commodity who had already done the job and ran a “joyful” and “forward-looking” campaign, she said, pointing to Trump’s visit to a McDonald’s franchise, rallies at concert venues, and his garbage truck ride.
Conway credited the campaign’s embrace of “new, new media” like TikTok, podcasts, and social media influencers, as a strategic move that paid real dividends in the final weeks reaching young men and low propensity voters. Also important was the campaign’s under-reported effort to educate disengaged voters about the many ways they could cast a ballot before Election Day, which also helped the former president prevail.
Over the past two weeks, Trump has announced more than two dozen nominees for White House and Cabinet positions, primarily top campaign staffers and high-profile business executives.
“What they all have in common is they know him; he knows them; and they are fluent in the America First agenda, meaning: This is what we’ve been elected to do,” Conway said. “So he’s got people who are willing to work with alacrity and energy to get that agenda through.”
At times, Conway flashed the quick and cutting fast-talk that has made her a polarizing figure on the left, sparring with student questioners.
She called for students to try to bring their friends who suffer from “Trump derangement syndrome” back to their senses.
“You all know someone afflicted by it. … It wrecks the nervous system. It addles the brain. There is no vaccine, cure, or therapeutic, but you all have a role to play in helping people at least unwind a little bit from it” by not canceling those who have a different point of view.
“I certainly hope that the new government that’s forming can rely upon, if not all of you right away, most of you along the way, to help in any way, shape, or form that you possibly can,” she said.
Health
Use of new diet drugs likely to mushroom
Study estimates over half of Americans eligible to take them based on diagoses, underscoring need to ensure equity of access.
BIDMC Communications
November 21, 2024
4 min read
In a new analysis of national data, an estimated 137 million U.S. adults, more than half of the adult population, would qualify for the anti-obesity drug semagludtide.
“Thes
Study estimates over half of Americans eligible to take them based on diagoses, underscoring need to ensure equity of access.
BIDMC Communications
4 min read
In a new analysis of national data, an estimated 137 million U.S. adults, more than half of the adult population, would qualify for the anti-obesity drug semagludtide.
“These staggering numbers mean that we are likely to see large increases in spending on semaglutide and related medications in years to come,” said corresponding author Dhruv S. Kazi, associate director of the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center. “Ensuring equitable access to these effective but high-cost medications, as well as supporting individuals so that they can stay on the therapy long-term, should be a priority for our clinicians and policymakers.”
The findings, which were presented at the American Heart Association Scientific Sessions and simultaneously published in JAMA Cardiology, underscore the need to increase equitable access to this new class of pharmaceuticals.
Semaglutide belongs to a class of drugs known as GLP-1 receptor agonists. It is currently approved to manage diabetes, treat overweight or obesity, and of recurrent cardiovascular disease. About 15 million adults take semaglutide, which stimulates the pancreas to produce insulin and reduces the hunger hormone ghrelin, decreasing the appetite and slowing down the rate of stomach emptying. As a result, semaglutide helps lower blood sugar levels and promotes weight loss.
Semaglutide is found to improve symptoms in sleep apnea and in some types of heart failure, and slows the progression of chronic kidney disease.
In 2023, it was the top-selling drug in the U.S. in terms of total pharmaceutical spending. But rapidly emerging data about its effectiveness for other health conditions is likely to further expand its use in future years. For instance, semaglutide is found to improve symptoms in sleep apnea and in some types of heart failure, and slows the progression of chronic kidney disease. Semaglutide and others in its class are currently being evaluated for treatment of liver and kidney diseases, substance use disorders, and dementia.
Ivy Shi, who is a resident in internal medicine at BIDMC, worked with Kazi to produce the analysis. They used five years’ worth of recent data from the National Health and Nutrition Examination Survey, a long-running survey of the U.S. population run by the U.S. Department of Health and Human Services, to identify U.S. adults aged 18 years or older who would be eligible for semaglutide treatment based on currently approved indications. They analyzed information about 25,531 survey participants gathered through in-person interviews, physical examinations, and laboratory testing.
They found that of the 136.8 million U.S. adults who qualified for semaglutide, 35 million would administer it for diabetes management, 129.2 million for weight loss, and 8.9 million for secondary prevention of cardiovascular disease. The semaglutide-eligible population includes 26.8 million adults covered by Medicare, 13.8 million covered by Medicaid, and 61.1 million covered by commercial insurance.
“The large number of U.S. adults eligible for semaglutide highlights its potential transformative impact on population health,” said Shi. “Prior studies have shown that more than half of the individuals who have taken these medications state the therapy was difficult to afford. Interventions to reduce economic barriers to access are urgently needed.”
Co-authors: Ivy Shi, Robert W. Yeh, Jennifer E. Ho, and Issa Dahabreh of BIDMC; and Sadiya S. Khan of Feinberg School of Medicine, Northwestern University.
Disclosures: Sadiya S. Khan reported grants from the National Heart, Lung, and Blood Institute outside the submitted work. Jennifer E. Ho reported grants from the National Institutes of Health during the conduct of the study. Issa Dahabreh reported a contract with the Patient-Centered Outcomes Research Institute and grants from the National Institutes of Health during the conduct of the study. Kazi reported grants from the National Heart, Lung, and Blood Institute, American Heart Institute, Agency for Healthcare Research and Quality, Patient-Centered Outcomes Research Institute, and Institute for Clinical and Economic Research outside the submitted work. No other disclosures were reported.
Funding/support: Dahabreh is supported by grants from the National Library of Medicine (R01 LM013616), the National Heart, Lung, and Blood Institute (R01 HL136708), and the Patient-Centered Outcomes Research Institute (ME-2021C2-22365).
Campus & Community
He didn’t come all this way to lose to Yale
Harvard coach Andrew Aurich answers questions from the media. Niles Singer/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
November 21, 2024
5 min read
Dream job and a winning season for Aurich, but one big test remains: The Game.
For many Crimson football fans, devotion can be measured by consecutive year
Harvard coach Andrew Aurich answers questions from the media.
Niles Singer/Harvard Staff Photographer
Christy DeSmith
Harvard Staff Writer
5 min read
Dream job and a winning season for Aurich, but one big test remains: The Game.
For many Crimson football fans, devotion can be measured by consecutive years of attendance at the Harvard-Yale game. But Saturday’s showdown will be a first for the man who now leads their beloved program.
“All the time I was playing at Princeton, and coaching at Princeton, I was kind of jealous of Harvard-Yale,” said Andrew Aurich, Thomas Stephenson Family Head Coach for Harvard Football. “I’m really excited to experience it.”
The first-time head coach, who came to Harvard from Rutgers University, has led the Crimson to an impressive 8-1 record. The team clinched at least a share of the Ivy League title with a dramatic win over the University of Pennsylvania last weekend, making Aurich the first head football coach in Harvard history to win a league title in his first season.
We caught up with Aurich to learn more about preparations for one of the biggest dates on the Crimson calendar. The interview has been edited for length and clarity.
The Crimson are having a great season under your leadership. To what do you attribute your early success?
Former head coach Tim Murphy played a big part in what’s happening this year. When I got here, it was very clear these players were already training to win a championship. They are very tough mentally. We’ve had some close games where our ability to focus at the end, and really execute, has allowed us to win.
Tell me about your leadership style.
One of the core parts of our culture is 100 percent honesty; the players are always going to get 100 percent honesty from me. Whether or not they like what they hear, they should know it’s coming from a good place. I expect the same from them. If there’s a better way to do something, I want to find a way to do that.
Aurich on the sidelines during the Harvard-Stetson game in September.
Credit: Harvard Athletics
What changes have you brought to the program?
My plan all along was to get an Ivy League head coaching job. But my experiences outside the league helped me see there were opportunities to help these young men become better players and a better team overall. If you ask them, they’ll say there’s a little more emphasis on sports science, whether it’s in the weight room or the emphasis we’re putting on nutrition, hydration, and sleep.
You said something interesting just now — that you always wanted to be a head coach in the Ivy League. Say more about that.
I knew I wanted to get into coaching when I was playing at Princeton. My dad had been my high school football coach, so I went back to St. Paul, Minnesota, and coached with him for a year and confirmed that I loved it. I ended up at a small Division 3 school in Pennsylvania for two years, and then I got the opportunity to go to Rutgers for my first stint as a defensive assistant.
From there I got the running backs coaching job at Princeton. My experience with the student-athletes there was so enjoyable. They’re just so driven and fun to be around. The next year I went to the Tampa Bay Buccaneers with my former boss at Rutgers, coach Greg Schiano. But as soon I got to the NFL, I immediately thought: “The Ivy League is where it’s at, I’ve got to do everything I can to become an Ivy League head football coach.”
What happened next?
I ended up back at Princeton. I was there for a long time, but saw that I needed something more than just Ivy League experience. When coach Schiano got the head coaching job at Rutgers again, I knew that working for him would help prepare me for success.
Landing the top job at Harvard must have felt like a dream fulfilled.
I was on the road recruiting with coach Schiano as the whole hiring process was underway. He doesn’t know the Ivy League all that well, so he was trying to get some perspective. “What is it like?” he wanted to know. I told him: “Coach, this is like being at Ohio State or [University of] Michigan in the Big Ten.” The entire time I was at Princeton — whether I was a player or a coach — I saw Harvard as top dog in the Ivy League.
How are you preparing for Yale?
Well, there’s definitely a different kind of energy right now. My job is to make sure our players are going about their business the same way they have been for the last nine weeks. This game means a lot to a lot of people. Even the level of the interest from the outside, including the number of media requests, is completely different from previous weeks. But ultimately, I can’t get caught up in it. Because if I am, I know the players are.
The Crimson fell to the Bulldogs in 2022 and ’23, but you’re the favorite this year. What do you hope to see on the field Saturday?
I want to see a team that is protecting the football on offense, that is taking the ball away in defense. I want to see a team that is executing 11 guys every play. I want to see a team that’s on the attack every single play. That’s how we define ourselves as a football program.
Will you get to participate in any of the fun stuff this weekend?
Hopefully the fun stuff I’ll be doing is celebrating a win.
Campus & Community
Ketanji Brown Jackson? Present!
Supreme Court Justice Ketanji Brown Jackson (left) with Michael Sandel and Margaret Marshall, former chief justice of the Supreme Judicial Court of Massachusetts.Photo by Grace DuVal
Christy DeSmith
Harvard Staff Writer
November 20, 2024
3 min read
Supreme Court justice revisits Michael Sandel’s class, which left her with lessons that lasted l
Supreme Court Justice Ketanji Brown Jackson (left) with Michael Sandel and Margaret Marshall, former chief justice of the Supreme Judicial Court of Massachusetts.
Photo by Grace DuVal
Christy DeSmith
Harvard Staff Writer
3 min read
Supreme Court justice revisits Michael Sandel’s class, which left her with lessons that lasted long beyond her time in it as first-year
In a passage from “Lovely One,” Supreme Court Justice Ketanji Brown Jackson ’92, J.D. ’96, is a Harvard College first-year drawing a smiley face in her notes for the course “Justice.”
“I want to laugh at the way my mind spins as I listen to the opinions being expressed,” she writes in a College essay excerpted in the new memoir. “I want to know the answers. I glimpse that there are no answers. Yet to wonder is not enough. We must never stop asking the questions.”
On Tuesday, Jackson was met by 800-plus smiles — and a standing ovation — as she returned to visit a course that proved influential in her life. Welcoming her at Sanders Theatre was Michael J. Sandel, the Anne T. and Robert M. Bass Professor of Government, who has taught “Justice” since 1980. Jackson credits Sandel’s Gen Ed offering with building her confidence while instilling a passion for healthy debate.
“I felt myself expanding and growing more visible to myself as I engaged the great philosophical conundrums,” she writes in the book. “The animated discussions about open-ended ethical dilemmas made me come completely alive.”
Seated with Jackson under the bright stage lights, Sandel invited students to engage with the issue of affirmative action while drawing on insights from influential philosophers, ancient and modern. Primary readings this semester include works from Aristotle, Immanuel Kant, and John Rawls. But the syllabus also features the 2022 U.S. Supreme Court decision rejecting affirmative-action policies at Harvard College and the University of North Carolina.
Some students lined up to share responses to Jackson’s dissent in the UNC case. (She recused herself in the case of Harvard, having served on its Board of Overseers.) Jackson may have been a quiet participant in “Justice” three decades ago, as she notes in the book. But she was much less so on her return to the two-hour lecture as she laid out her legal and moral reasoning on affirmative action. The whole exchange was off the record.
Taking the stage to address the class for the final 45 minutes of the session was Margaret Marshall, Ed.M. ’69, former chief justice of the Supreme Judicial Court of Massachusetts. Sandel assigned students to read her 2003 opinion in Goodridge v. Department of Public Health, which established the right to same-sex marriage for the first time in U.S. history. Sandel said that Marshall’s opinion is a rare piece of legal writing with the resonance of prayer. It has found second life as a popular reading at weddings nationwide.
Campus & Community
Harvard, MIT, Mass General form renewable energy collaboration
Group will include higher education, healthcare, and cultural institutions, seek to leverage buying power to advance cost-effective projects
Amy Kamosa
Harvard Correspondent
November 20, 2024
4 min read
The Big Elm Solar Project located in Bell County, Texas, came online this year.Credit: Apex Energy
Har
Harvard, MIT, Mass General form renewable energy collaboration
Group will include higher education, healthcare, and cultural institutions, seek to leverage buying power to advance cost-effective projects
Amy Kamosa
Harvard Correspondent
4 min read
The Big Elm Solar Project located in Bell County, Texas, came online this year.
Credit: Apex Energy
Harvard announced on Wednesday the formation of the Consortium for Climate Solutions, a first-of-its-kind renewable energy collaboration of higher education, healthcare, and cultural institutions, as well as state and local government entities, led by Harvard, Mass General Brigham (MGB), and the Massachusetts Institute of Technology (MIT).
The consortium will leverage its members’ collective purchasing power to overcome market conditions that serve as barriers to development of projects that advance cost-effective renewable energy and allow for larger-scale investment.
“With these new utility-scale renewable electricity projects, Harvard will purchase the equivalent of 100 percent of its electricity from renewable sources, fulfilling a key component of our approach to meet our goal to be fossil fuel-neutral by 2026.”
Heather Henriksen, chief sustainability officer
“Investing in new, large-scale renewables marks a significant step forward for Harvard in its commitment to a clean energy future,” said Meredith Weenick, executive vice president. “By founding the consortium with MIT and MGB, we are not only catalyzing the transition to a cleaner grid but also demonstrating a collaboration model that will enable a variety of nonprofit organizations and municipalities to work together to address the urgent challenges of climate change.”
The consortium recently finalized negotiations that will result in the development of 408 megawatts of new renewable energy through two large-scale, utility-grade projects — the Big Elm Solar in Bell County, Texas, and the Bowman Wind Project in Bowman County, North Dakota. The 200-megawatt Big Elm Solar project came online earlier this year, and the 208-megawatt Bowman Wind project is expected to come online in 2026. Collectively these projects will generate clean power equal to the electricity use of 130,000 U.S. homes annually.
“With these new utility-scale renewable electricity projects, Harvard will purchase the equivalent of 100 percent of its electricity from renewable sources, fulfilling a key component of our approach to meet our goal to be fossil fuel-neutral by 2026, while we simultaneously work on the longer-term effort to decarbonize our historic and urban campus,” explained Heather Henriksen, Harvard’s chief sustainability officer.
Achieving fossil-fuel neutrality by 2026 is a bridging strategy to mitigate the negative impact of fossil fuels on emission levels and air pollution while the University develops longer-term technology and infrastructure changes to eliminate its use of fossil fuels by 2050. In addition to purchasing electricity from renewable sources, the University looks to seek greater energy efficiency and heat recovery on campus, replace fossil-fuel equipment at the end of life, increase its electric vehicle fleet, and find other reductions of fossil-fuel use.
“There is plenty of scientific evidence that fossil fuels are negatively impacting health, community stability, and ecosystems around the world. As Harvard continues on its path to become a fossil fuel-free campus, it is critical that the University not only conduct research on how to drive down global emissions and bolster adaptation, but to use our purchasing power to help produce cost-effective renewable energy solutions at scale,” said Mike Toffel, the Senator John Heinz Professor of Environmental Management at Harvard Business School, faculty chair of the Business and Environment Initiative at HBS, and co-chair of the Presidential Committee on Sustainability. “The consortium is an excellent example of engaging with the renewable electricity markets to expand their scale and impact.”
The consortium founding members, Harvard, MGB, and MIT, sought opportunities to collaborate with smaller nonprofits and municipalities. This resulted in the partnership with PowerOptions, a nonprofit energy-buying organization, enabling the city of Cambridge, Beth Israel Lahey, Boston Children’s Hospital, Dana-Farber Cancer Institute, Tufts University, the Mass. Convention Center Authority, the Museum of Fine Arts, and WGBH to join under the PowerOptions umbrella. The consortium is providing PowerOptions members with access to affordable, large-scale renewable energy purchases that would typically be out of reach for individual buyers.
The creation of the consortium, supported by Harvard’s leadership, was led by the Office for Sustainability working with faculty and other key stakeholders. The projects chosen for investment align with the recommendations and criteria set forth by the Fossil Fuel-Neutral by 2026 Subcommittee of the University’s Presidential Committee on Sustainability. The consortium vetted more than 100 potential projects, ultimately choosing the Big Elm Solar and Bowman Wind projects from developer Apex Clean Energy.
Locally, the consortium’s power-purchase agreements with the Big Elm and Bowman projects will enable its members to accelerate progress toward their individual sustainability goals consistent with local emissions-reduction regulatory targets, while simultaneously reducing fossil fuel emissions at a national scale.
“The locations and scale of each project, in two of the most carbon-intensive electrical grid regions in the United States, mean that the potential positive impact is significant, creating a more robust and cleaner grid,” explained Henriksen.
Health
Rapid relief for the severely depressed? There’s a catch.
Liz Mineo
Harvard Staff Writer
November 20, 2024
6 min read
Ketamine carries risks, say researchers. Yet for some patients, it’s ‘the only thing that works.’
At the Ketamine Clinic for Depression at Massachusetts General Hospital, patients make their way each day to receive intravenous infusions of the powerful anesthetic
Rapid relief for the severely depressed? There’s a catch.
Liz Mineo
Harvard Staff Writer
6 min read
Ketamine carries risks, say researchers. Yet for some patients, it’s ‘the only thing that works.’
At the Ketamine Clinic for Depression at Massachusetts General Hospital, patients make their way each day to receive intravenous infusions of the powerful anesthetic that has become an alternative therapy for treatment-resistant depression.
Many of the clinic’s patients have not been helped by traditional treatments, including psychological counseling, antidepressant medication, transcranial magnetic stimulation, and electroconvulsive therapy. With its rapid antidepressant effects, ketamine is sometimes the only option that provides relief, said clinic founder and director Cristina Cusin, who has been researching depression and mood disorders for the past 25 years.
“We don’t have good weapons to treat some severe forms of depression, just like we don’t have treatments for advanced-stage cancer,” said Cusin, who is also an associate professor in psychiatry at Harvard Medical School. “We’re always looking for the next thing so that we can continue to offer hope to patients who don’t respond to standard treatments.”
In 2000, after a study reported that small doses of IV ketamine rapidly reversed symptoms of depression while standard antidepressants often took several weeks to have an effect, ketamine became the next new thing. In 2019, based on years of research, the FDA approved a nasal spray medication, derived from ketamine, to be administered under medical supervision.
Depression is a mental health disorder characterized by feelings of sadness and hopelessness, that affects 18 percent of Americans. One-third of those diagnosed with depression don’t respond to standard treatments, with acute consequences to their personal and professional lives. The stigma associated with depression makes it harder for people to seek treatment, said Cusin.
“There are some forms of depression that have a strong biological component; there are neurocircuits in the brain that are not functioning right. In many cases, it’s not for lack of trying.”
Cristina Cusin
“In our society, if you suffer from depression, you may be told to ‘try harder,’ ‘stop complaining,’ ‘pick yourself up by your bootstraps,’ and so on,” Cusin said. “But there are some forms of depression that have a strong biological component; there are neurocircuits in the brain that are not functioning right. In many cases, it’s not for lack of trying.”
Patients follow a strict protocol to be admitted to the MGH Ketamine Clinic; not only do they have to be referred by their primary prescribers, but also prior treatments for depression must have failed. Ketamine therapy is integrated with other treatments and is done in the clinic under medical supervision and in coordination with patients’ primary medical teams. The clinic doesn’t admit self-referred patients or those with active substance use disorders or a history of psychosis. Ketamine produces hallucinogenic effects and dissociation, which can exacerbate psychotic symptoms.
Other risks associated with ketamine are the possibility of developing addiction and a host of medical problems, but for patients who experience rapid relief from their symptoms of depression after treatment, ketamine is a game-changer, said Cusin. “Our patients have failed other treatments, so they don’t have a lot of other options,” she said. “If this is the only thing that works, they keep coming.”
Scientists continue researching ketamine’s antidepressant effects on treatment-resistant depression. A recent clinical trial found that ketamine was as effective for non-psychotic treatment-resistant depression as electroconvulsive therapy (ECT), which has long been the gold standard for hard-to-treat depression.
Conducted by Amit Anand, professor of psychiatry at Harvard Medical School, the study found that 55 percent of those receiving ketamine and 41 percent of those receiving ECT had at least a 50 percent improvement in their self-reported depression symptoms. Anand co-authored the pivotal 2000 study that revealed the rapid antidepressant effects of ketamine.
Encouraged by his recent study’s results, Anand is conducting a follow-up clinical trial comparing ketamine and ECT treatments among patients with suicidal depression. If ketamine can affect suicidal thoughts, it could be lifesaving. “What we’re trying to see is that if ketamine can cause a very rapid reversal of the troubling kind of depression leading to suicidality,” he said. “People are suffering, and even if it is for a short time, it is beneficial to provide a rapid change.”
“What we’re trying to see is that if ketamine can cause a very rapid reversal of the troubling kind of depression leading to suicidality.”
Amit Anand
Even though doctors and researchers are hopeful regarding the promise of ketamine, there is growing concern about the proliferation of private ketamine clinics, which began to crop up around the country after restrictions on telemedicine relaxed during the pandemic. These clinics offer IV ketamine infusions, with prices ranging from $600 to $800 per infusion.
Most ketamine private clinics operate in a gray zone, with almost no oversight, and function as for-profit businesses, said Peter Grinspoon, a primary care physician, educator, and cannabis specialist at MGH.
“The end result is that now our population has broad access to ketamine, and it’s a little bit of an uncontrolled experiment,” said Grinspoon. “Whether it’s going to alleviate many people’s depression or whether it’s going to get a lot of people addicted to ketamine is going to be an open question. We don’t know how much it is going to help or harm things.”
Ketamine is not nearly as addictive as alcohol or opioids, but its use as a recreational drug poses serious risks. Actor Matthew Perry died last year of “acute effects of ketamine.” His autopsy also found opioids in his blood, but the level of ketamine found was equivalent to the amount that would be used during general anesthesia.
The other troubling issue for Grinspoon is affordability. “I work as a primary care doctor in an inner-city clinic,” he said. “None of my patients can afford six $800 injections. … The last thing we need is for ketamine to be another treatment for just the well to-do. … This has got to be affordable.”
At the MGH clinic, patients receive low doses of ketamine in long intervals and have mixed experiences. While some report feeling relaxed, others find it unpleasant, but most said their symptoms of depression improve and don’t interfere with day-to-day functioning. Still,
Cusin warns that ketamine should not be a first-option treatment for depression.
“If someone is depressed or suicidal, there are alternatives out there,” said Cusin. “There are 50, 80 different treatments to consider. It’s rare that somebody has tried everything. Usually, there are entire classes of medications or treatments that have not been considered. There is always hope.”
Campus & Community
Culture Lab Innovation Fund grants awarded to 12 projects
Grant recipients foster a culture of innovation and belonging on Harvard campus
Laurie Rodriguez
Harvard Correspondent
November 20, 2024
6 min read
The Lighting for Diverse Skin Tones project holding an in-person lighting master class for Harvard media professionals. Photo by Julia King
Twelve projects have r
Culture Lab Innovation Fund grants awarded to 12 projects
Grant recipients foster a culture of innovation and belonging on Harvard campus
Laurie Rodriguez
Harvard Correspondent
6 min read
The Lighting for Diverse Skin Tones project holding an in-person lighting master class for Harvard media professionals.
Photo by Julia King
Twelve projects have recently been awarded grants from the Harvard Culture Lab Innovation Fund (HCLIF) for the 2024–2025 cycle. Harvard students, faculty, staff, postdoctoral researchers, and fellows submitted grant proposals for projects aimed at fostering an inclusive environment at the University. Each project aligns with HCLIF’s mission to “encourage experimentation, build a culture of inclusion, and grow a network of equity, diversity, inclusion, and belonging innovators at Harvard,” while also supporting the University’s goal of achieving inclusive excellence. Funded by the Office of the President and administered by the Office for Equity, Diversity, Inclusion, and Belonging, these grants range from $5,000 to $15,000.
“Harvard is committed to continuing its investment in innovative ideas that promote a campus culture of inclusion and belonging,” said Sherri Charleston, chief diversity and inclusion officer. “These grassroots projects unite community members at all levels of the University — researchers, students, faculty, postdocs, and staff — who identify pressing campus needs and apply their expertise to develop solutions. From a series exploring faith and justice to a project creating inclusive medical illustrations, the HCLIF projects are transforming ideas into action and making a significant impact.”
“From a series exploring faith and justice to a project creating inclusive medical illustrations, the HCLIF projects are transforming ideas into action and making a significant impact.”
Sherri Charleston, chief diversity and inclusion officer
This year’s project teams showcase cross-University collaboration, with members representing Schools and units from across Harvard.
The awardees include the Lighting for Diverse Skin Tones project, a second-year grant recipient. It is a University-wide training resource that educates video producers and media professionals at Harvard on how to create lighting that captures a variety of skin tones effectively in photography, especially skin tones previously overlooked in photography and film training. With additional funding, they will work to identify a host site for the project and complete editing of previously recorded videos. “This project started with the intention of honing media producers’ skills in the craft of inclusive cinema lighting, but we ended by finding the time and space to really see people and understand how they want to be represented,” said Julia King, creative video producer at the Harvard T.H. Chan School of Public Health, and Jacob Beizer, senior digital content producer and strategist at the Harvard Kennedy School in a statement. “We are excited to provide this resource to the entire Harvard community.”
The Inclusive Anatomical Images project stems from collaborations between Harvard Medical School, Harvard Art Museums, and the University of Global Health Equity based in Rwanda. The project seeks to ensure diverse patients have a higher chance of being better served and aims to improve patient outcomes by creating more inclusive educational medical literature. It creates materials reflecting a diversity of bodies — including various sizes, ancestries, genders, and skin tones — to better serve a wide diversity of patients. With this year’s funding, the team will expand their reach by making their resources more accessible to institutions, researchers, and health professionals beyond Harvard, while expanding their team to meet the demand for their expertise and images. Martha Ellen Katz, a faculty member of the Harvard Medical School, said, “Our project has the potential to validate the life experience of historically excluded patients, physicians, dentists, and student learners at HMS, and curricula worldwide. Our equitable work culture, which strives to be as non-hierarchical as possible, also encourages student leadership and acknowledges the essential contributions of all team members, collaborators, and supporters.”
The Connecting Community Through Food project celebrates Harvard’s student body through food. By collaborating with Harvard College students, student organizations, and employees, the Harvard University Dining Services team aims to develop recipes and menus authored by Harvard undergraduates from a diversity of backgrounds. These meals will be served more regularly in dining halls. Smitha Haneef, executive director of the Harvard University Dining Services, explained, “We want students to experience the dining halls as welcoming, comforting places, hopefully like their home kitchens. For this to happen, the menus must feel like home. This project helps us realize that vision for more community members.”
Additional 2024 HCLIF Recipients
Community Project on Faith and Justice cultivates inclusivity and engagement centered on faith by hosting speaker series and community events where affiliates can explore the influence of faith in their lives.
Disability Awareness Series aims to increase awareness about the resources available for, and challenges faced by, those with disability and accessibility needs at Harvard. It engages Harvard College students, staff, researchers, and faculty through an awareness campaign and series of events.
Disability in Health Professions Mentorship Program cultivates a supportive community for current and future health professionals living with disabilities and chronic illness, fostering a greater sense of belonging at Harvard.
Emerging Scientists Program connects high school students from Cambridge and Boston with Harvard graduate students, postdoctoral researchers, and staff, providing meaningful and accessible life sciences research experiences.
Harvard Career Capsule empowers graduate students by providing professional attire and equipment to support their career development.
Harvard University Peer Coaching Initiative aims to reduce loneliness and enhance interpersonal skills by pairing Harvard students and researchers. Participants engage in weekly sessions over the course of a semester to practice effective listening with one another.
Justice-Impacted Inclusion seeks to make Harvard more inclusive of formerly incarcerated people and others impacted by the justice system. The initiative consults with formerly incarcerated policy experts and creates resources, such as a guide on inclusive language and practices.
LifeSaveHer develops trainings to address misconceptions regarding performing CPR on women, including modifying male CPR mannequins to represent female bodies, ultimately aiming to reduce cardiac arrest survival disparities for women.
Trans+ Community Celebration at Harvard seeks to uplift the trans+ community by creating inclusive spaces within the University.
Applications for the 2025-2026 funding term of Harvard Culture Lab Innovation Fund grants are now open to Harvard students, faculty, staff, postdoctoral researchers, and academic personnel. Harvard community members interested in participating as judges for the 2025-2026 HCLIF grant applications can now sign up.
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Health
‘Harvard Thinking’: New frontiers in cancer care
In podcast, experts discuss breakthroughs in treatment, from genomic sequencing to AI, and how close we are to personalized vaccines
Samantha Laine Perfas
Harvard Staff Writer
November 20, 2024
long read
Cancer kills nearly 10 million people worldwide every year, but advances in genomic sequencing, artificial intelligenc
In podcast, experts discuss breakthroughs in treatment, from genomic sequencing to AI, and how close we are to personalized vaccines
Samantha Laine Perfas
Harvard Staff Writer
long read
Cancer kills nearly 10 million people worldwide every year, but advances in genomic sequencing, artificial intelligence, and other technologies are ushering in a new era of treatment.
Alumnus Levi Garraway, who runs late-stage drug development at the biotech company Roche and previously worked at the Dana-Farber Cancer Institute, said the field has come a long way.
“Although cancers may look the same under the microscope, they can be very different when you look at the DNA,” Garraway said. That’s why the pillars of cancer treatment — surgery, radiotherapy, and chemotherapy — are so limited in their applications. Moving to more personalized treatments based on a patient’s genetics has revolutionized the field. “[Genetic sequencing] was one of the first breakthroughs that allowed cancer treatment to start to become a bit more personalized.”
Connie Lehman, a professor of radiology at Harvard Medical School and a breast imaging specialist at Mass General Brigham, said artificial intelligence has shown remarkable promise in detecting breast cancer, with success rates that far exceed what the human eye can detect alone. “What [other industries] are doing in computer vision is just unbelievable. And bringing that into healthcare to improve the lives of our patients is incredibly exciting.”
Treatment and prevention will only become more personalized and effective as researchers continue to explore the human genome and genetic structure of cancers, said Catherine Wu, a professor of medicine and chief of the Division of Stem Cell Transplantation and Cellular Therapies at the Dana-Farber Cancer Institute. One question that drives some of her research: Is it possible to vaccinate against cancer?
“That’s the vision,” said Wu, a recent recipient of the Sjöberg Prize for cancer research. “Can we, for example, make cancer vaccines as available as, say, the COVID vaccine was? That was a huge rollout given to all citizens of our country. How were we able to roll that out quickly and safely?”
In this episode of “Harvard Thinking,” host Samantha Laine Perfas talks with Garraway, Lehman, and Wu about some of their most cutting-edge cancer research — and what hope lies on the horizon.
Transcript
Levi Garraway: And now all of a sudden, it’s not quite such a blunt instrument. You’re able to get a much more selective killing effect of the cancer. Now you have a way to tell in advance who might respond to this treatment. That was one of the first breakthroughs that allowed cancer treatment to start to become a bit more personalized.
Samantha Laine Perfas: Advances in technologies like genomic sequencing and artificial intelligence have ushered in a new era in the fight against cancer, which kills nearly 10 million people worldwide every year. Researchers are now working on therapies that can be genetically tailored to individual patients and they’re also working on methods for discovering cancers at much earlier stages. Someday, we might even have vaccines that can prevent the disease altogether.
How close are we to turning a corner on cancer?
Welcome to “Harvard Thinking,” a podcast where the life of the mind meets everyday life. Today, we’re joined by:
Garraway: Levi Garraway. I run late-stage drug development at Roche, which in the U.S. is known as Genentech.
Laine Perfas: Levi attended Harvard as an undergraduate, graduate, and medical student. He also worked at the Dana-Farber Cancer Institute for 11 years. Then:
Connie Lehman: Connie Lehman. I’m a professor of radiology at Harvard Medical School and I’m a breast imaging specialist at Mass General Brigham.
Laine Perfas: She’s also a founding partner at Clairity, which uses the power of artificial intelligence to better inform precision care. And finally:
Cathy Wu: Cathy Wu. I am a professor of medicine and division chief for transplant and cellular therapies at Dana-Farber Cancer Institute.
Laine Perfas: She was an undergraduate at Harvard and completed her clinical training at the University. Recently she received the Sjöberg Prize for cancer research.
And I’m Samantha Laine Perfas, your host and a writer for The Harvard Gazette. This episode looks at the future of cancer treatment.
Historically, how have we approached cancer treatment and how has that shifted in recent years?
Garraway: Historically you had surgery, you had radiotherapy, and you had chemotherapy. I put historically in quotes because these are all in wide use today, and they’re probably not going anywhere anytime soon. And the reason why they’re not going anywhere is because they actually can be effective in treating many cancers, even curing some cancers, but there are well-known limitations. And of course, I think for all of us who went into this field, it was in part to try to counter those limitations. And one is that there’s a whole lot of cancers that can’t be cured with those therapies, and the other is that these are all blunt instruments. I mean, often you get damage to normal or adjacent cells and tissues as well as cancer cells. And that’s a big problem. You often can’t tell in advance who’s going to respond or who’s not going to respond, for example, to chemotherapy. So it’s a vexing issue when you have a patient and you know they need treatment, but you can’t tell them that they’re going to benefit from a potentially toxic treatment.
Wu: Yeah. I agree with Levi. I think we were taught that the pillars of cancer care have been chemotherapy, radiotherapy, and surgery. I think what’s been exciting in the lifetime that we are going through our training and treating our patients is that we’ve seen so much evolved that there are actually new pillars that have been coming up and so I think that one of the things that kind of worldwide that we’re excited about is immunotherapy because this has emerged as a fourth pillar that is touching on all the different disease types and has proven to be really important.
Lehman: It is really exciting to see this transition to more targeted and more personalized treatment. Also at the other end of the spectrum is, can we actually even prevent cancers? Like, are there domains where we don’t need to wait until they’re so far advanced that cure is really elusive even with the most advanced therapies? So in my part of the sandbox, we’re really focused on early detection and also accurate risk assessment so we can have the right interventions to prevent the cancer from developing. It’s so interesting to look at the changes in how breast cancer presents. You can have women moving from one country to another, to adopting different diets, different lifestyles, and their breast cancer risk goes up within their lifetime. So there are these correlations between modifiable risk factors and lifestyle, diet, exercise, environmental, carcinogens, and how can we be better at identifying those and really stopping the cancer from occurring?
Laine Perfas: Treatment has become a lot more personalized in many ways. The historical treatment, if this is accurate, it seems like it was very much one-size-fits-all. What were some of the problems of that approach and why did that need to change?
Garraway: One major recognition that happened over time is that you could have two women with breast cancer, they’re both called breast cancer, but they behave very differently. They may show up very differently. They respond differently to treatment. There’s now a lot more understanding about why that is. And one big reason is that although cancers may look the same under the microscope, they can be very different when you look at the DNA, the genomes of those cancers. They’ve acquired mutations of various types. Some of them are completely random and they don’t matter to the cancer, but others are critical. They become what we call drivers of the cancer. So when we talk about what made cancer become more personalized, it was the recognition that some of those mutations, they occur over again in certain subsets of cancer, but you can design medicines against the resulting mutated proteins that drive the cancer. And those medicines are now much more selective. Now all of a sudden, it’s not quite such a blunt instrument. You’re able to get a much more selective killing effect of the cancer. Now you have a way to tell in advance who might respond to this treatment. That was one of the first breakthroughs that allowed cancer treatment to start to become a bit more personalized.
Wu: A lot of innovation follows technology. So I think that it’s always been recognized that you can try to do one-size-fits-all. But the reality is that not everyone responds and patients do or do not have toxicities. So I think the kind of technology that has brought so much insight has been through unraveling the molecular secrets of cancer cells through sequencing. I think that very, perhaps, simple technological advance has meant the world to what we understand about cancer now. And at some level, I think that the personalization is what is fighting fire with fire. You’re confronting that heterogeneity up front. You’re not trying to hide from it. You’re acknowledging that it exists and that it actually mandates that we become more selective in terms of how and what we can offer to our patients.
Lehman: I really like how both Levi and Cathy talk about [how] this personalized domain is about getting the fit with the patient and that patient’s tumor and the treatment. We see that in other domains of medicine. So, for example, we can look back at old studies and there was a drug therapy that people were very excited about, and the results were mediocre and everyone abandoned and moved on. But there were some patients that responded really well. So you want to go back and say, it wasn’t necessarily a bad treatment. It was a bad selection of the patients that could benefit. If we can be more tailored and more personalized and more targeted, will there be a lot of drugs that had been like, this isn’t a great way to approach treating quote, breast cancer, which is far too broad of a term to use. Exactly the same analogy happens in the imaging sciences and radiology. We had a boon in developing new technology for breast imaging from old film screen to digital mammography to tomosynthesis to contrast-enhanced mammography to MRI to nuclear medicine scans to ultrasound. Everyone’s really excited, and we were trying to use these in screening, and some of them give orders that, well, we can’t screen with ultrasound, there are too many false positives, we can’t screen with MRI, it’s too expensive and we can’t afford it and the value proposition isn’t there. But what we needed to do was to say, what if you targeted the right population, that, one, is disadvantaged with mammography and, two, is really at high risk for having a cancer aggressively grow and fail to be detected by mammography? And if you targeted those high-risk patients, all of a sudden these technologies look a lot better, look a lot more powerful.
Laine Perfas: Cathy, one of the things you mentioned that I wanted to ask about was genetic sequencing. I believe it just was so time-consuming and expensive in the past that it wasn’t really a practical thing that could be done on a patient-by-patient basis. How has that changed and what doors has that opened with research?
Wu: It’s been huge. In short, I think the big change happened around 2008-09, more or less, where suddenly from the exorbitantly expensive experience of running the Human Genome Project, there was new technology available that suddenly made it possible to sequence on the order of hundreds to low thousands, which still sounds like a lot. That was back then. Now we’re coming down to the low hundreds per sample. We are already testing the waters, but I really do think it’s a reality that in the not-too-distant future that this should be a diagnostic test that can be offered that is a standard part of your cancer workup. As we as a community gain more experience, this experience can be aggregated and we can look for patterns and we can look for opportunities that can at one level afford personal opportunities, but also at a population level find perhaps therapies that can benefit another population that may share those kind of genetic characteristics.
Garraway: I’ll add a couple of points. One is that what Sam described, the laborious nature of sequencing, the unlock, as you point out, that happened coming close to two decades ago, was the ability to sequence at scale. So this technology called Massively Parallel Sequencing came on the scene, and now all of a sudden, where it used to be so laborious to even sequence one gene, and there are 20,000 genes in the genome and there are many hundreds that are critical in cancer, now all of a sudden you can sequence dozens or hundreds of genes at a time. Eventually, as Cathy mentioned, it’s become possible to sequence whole genomes routinely and many times over. So the expansion of technology has been remarkable. The other thing that it is enabling is possibly a new generation of what Cathy mentioned: immune therapy. It may be that in the fullness of time, the same sequencing technologies will figure out mutations that actually now cause a tumor to look more foreign. There can be new ways to target the immune system with that information, but that’s also very personalized information. Each tumor will have a different set of mutations or changes like that. So this is a direction that immunotherapy is taking. It’s early days but it looks very intriguing.
Laine Perfas: Is it accurate to say that there could be a future where we might be able to vaccinate against cancer or treat people with personalized vaccines for their specific case?
Wu: That’s the vision. I think that if we are going to be able to offer sequencing as a routine test, then the information content that is provided by that test not only allows you to understand maybe some of the origins of where that kind of cancer came from, what were the steps that made it into the cancer that it was, but it also provides you with different therapeutic opportunities. That gets into another interesting topic, which is, how can we, for example, make cancer vaccines as available as, say, the COVID vaccine was, right? So that was a huge rollout given to all citizens of our country. How were we able to roll that out quickly and safely? A cancer vaccine is far more complicated. Some of the principles, though, are very similar. But because of the scale of that difference in the personalization, it is more complex. On the other hand, the ingredients to make that type of vaccine are contained within the sequencing information that I think we would all envision would be a routine test in the not-too-distant future.
Lehman: I also think it’s exciting, and we’re becoming more and more sophisticated and not thinking of the multitude of cancers as cancer. So a vaccine against cancer is almost like thinking, will we have a vaccine against a virus? And so we have areas that have been incredibly exciting during my career where I certainly didn’t think when I was a medical school student and learning about cervical cancer that we would have a vaccine to prevent HPV infection and that would eradicate a very large percentage of cervical cancers in patients that are vaccinated and that also can reduce the occurrence of prostate cancer. So there’s a whole domain that you can actually stop the trigger for the cancer to be able to develop rather than wait and then see that there’s circulating cancer cells and now let’s come in and let’s try to have the body help fight away those cancer cells.
Laine Perfas: Connie, early detection is an area that you’re really passionate about. And actually in the work you’ve been doing, you’ve been using AI. I would love to hear more about that and how AI is being used to detect breast cancer sooner.
Lehman: Part of the different changing face of breast cancer has been mammography screening. Mammography is a very imperfect tool, but it did change the spectrum of patients presenting with breast cancer. We shifted historically from women coming forward when they noticed that there was a lump in their breast, or a doctor noticed that, and we could find cancers preclinical before that happened, and we really saw a shift in both the morbidity of the treatment, but also the survival.
That was a big win, but as I said it’s limited, and we have women presenting with advanced cancer despite routine screening. We have the costs and the false positives and the challenges of using mammography effectively. So I think that what I’m most excited about is changing the paradigm of how we screen and moving away from a very archaic age-based approach and moving into a risk-based approach.
Everyone has seen over the years the arguments about screening mammography. In Europe they tend to start at 50 and screen every two to three years. In the U.S. we constantly battle about whether you start at 40 or 50 and it’s every year or every two years. That argument is so limited. It’s almost unbelievable to me that we’re still having a basic argument about 40 or 50 or every year or every two years when there’s such a diversity of the risk profiles of women within their 40s, within their 30s, within their 50s, and we ignore that. Now one of the reasons why we’ve ignored it is our traditional risk models are inadequate. So the area I’m most excited about with artificial intelligence is using computer vision, not to look for cancer currently on the mammogram, but to predict whether that woman will develop cancer within the coming five years. So if you can look out into the future, is there something about this tissue that is putting this woman at increased risk? And our research to date shows that the AI applied to the basic regular mammogram can predict future breast cancer at a level that we just haven’t seen before.
It also eliminates the really unfortunate racial biases in our traditional risk models, which were built largely on European Caucasian women, and just don’t perform for us in Black, Hispanic, and Asian women. There’s a whole other domain, too, of having the computers learn how to read the mammograms, because one of the limitations of mammography is you need these highly specialized humans to read them, which really reduces the impact of screening mammography globally, because we just don’t have enough highly specialized radiologists to interpret the mammograms. So I think we’ll also see that shift.
Garraway: We could have a whole conversation, of course, on AI in medicine, and what Connie described in radiology is so exciting. It’s really going to be revolutionary. I’ll just say at a high level that AI is already changing every component of the research and development of new medicines, starting all the way from the very beginning, where you can use AI to conduct a lot of the compound screening or chemical screening in a computer. Where it used to be, you have to have lots of expensive chemical libraries and iterative screening of things. A lot of that can be done in silico, as we call it, because of AI, and even design of therapeutic antibodies from scratch, using AI-first principles. Then when you get into the clinic, the ability to synthesize all kinds of patient data to predict the kinds of patients that one should study so that you’re not fooled either in the positive or the negative way about whether a medicine is working. So it’s hard to come up with a component of the research and discovery of medicines that’s not being impacted by AI.
Laine Perfas: A lot of Connie’s work involves using AI for mammography and then Levi, you mentioned really every area of medicine is being revolutionized. Are there other emerging technologies that are really changing the landscape of cancer detection, treatment, and lowering morbidity rates?
Wu: I think there’s a lot of exciting technologies that are among us right now. It’s not for nothing that we’re in the age of human biomedicine that we actually can learn directly from human biospecimens as opposed to fruit flies, worms, and mice, which is really how we gained our insights in the past. Along the lines of some of the AI work, there’s a tremendous interest, not only unlocking the secrets one cell at a time, looking at the DNA, the RNA, the protein expression, but also looking to see how all of these cells in, for example, tumor tissue, are patterned, are organized in space. These patterns on the one hand are teaching us how the cells are interacting with each other and allowing us to relate that to patient characteristics. So for patients who are destined to respond or not respond to a particular therapy, what were the patterns that were seen? And what does that tell us about the biology that happened? A lot of that information can also be fed into AI-related algorithms so that we can become better at pattern recognition.
Lehman: Yeah, Cathy, I like how you’re presenting that because it is where, again with these multidisciplinary approaches, the more I interact with specialists in computer science and artificial intelligence, the more I realize how much we really need their expertise just infusing healthcare. Because what we deal with is, we’ve had this incredible renaissance where we have so much technology that can collect so much data and in the imaging sciences alone. I think about, when I started, the kinds of images I would look at with plain films and a chest X-ray and a mammogram and then the complexity of the way that we can image the human body and the data that results from that. But the technology to collect that information, to create those patterns, just far exceeds our ability as humans. From the military, from the auto industry, I mean, what they’re doing in computer vision is just unbelievable. And bringing that into healthcare to improve the lives of our patients is incredibly exciting.
Garraway: Sam, you asked the question about other kinds of technologies. Of course, as Connie’s mentioning, AI pervades all of them, but I will mention there are technologies that are also allowing new kinds of cancer treatments to emerge. There are now what we call treatment modalities, which are different than were possible in the past. I’ll just mention a couple of them.
One is what we call cellular therapy. So this is a technology platform. You basically collect certain kinds of immune cells from an individual and then you expand them in the laboratory. You engineer them so that they can destroy tumor cells very effectively and then you give them back to patients. And so, the first generation of cell therapy, you would collect those cells from a patient with, let’s say a blood cancer, and then you engineer them and you give them back to the same patients. That actually often works remarkably well. You can get very profound clinical benefit in patients who otherwise weren’t going to benefit at all. But as you might imagine it’s logistically challenging to do this for every patient, and in every center and every context. So not as many patients have access to cell therapy as one might like.
So there’s now a new kind of emerging generation of cell therapy. The technical term is allogeneic cell therapy. In that setting, what you do is you collect immune cells from completely unrelated donors, and you expand them and you engineer them, just like we talked about, but then you can store them so that in the future, you have, like, an off-the-shelf way of leveraging this cell therapy. You don’t have to do the whole start-to-finish process on every single patient, every single time. We think this is potentially a really exciting, future promise. Then the other platform I’ll just mention very briefly, it’s called bispecific antibodies. Traditionally one kind of therapy we call a therapeutic antibody, it’s a mimic of the immune system but it allows you to design an antibody that binds a particular disease target very tightly. But bispecific antibodies work by binding not just one target, but two targets. So if one target is on the tumor cell and the other target is on the immune cell, the bispecific antibody can bring the immune cell to the tumor cell and activate the immune cell and kill the tumor cell. So I just want to bring up that we talked a lot about AI as it’s revolutionizing everything, but there are other kinds of platforms that we use more and more in the pharmaceutical arena to try to develop new kinds of medicines that can bring new kinds of benefits.
Laine Perfas: Hearing about all these emerging therapies is so exciting and amazing and miraculous-seeming, especially as someone who is not a cancer researcher. But I also want to acknowledge that there’s still challenges there, you know, there’s costs, resources, still limitations on technology. A lot of it is just a lot of work.
Wu: We know. Oh, we know.
Laine Perfas: So what keeps you all hopeful with the current trajectory and where do you see us being or hope we’ll be 10 years from now, 20 years from now?
Wu: I think the hope comes from all the progress that we see. It is incremental. I think all of us know the challenges but experience the positive signals that kind of give us hope and tell us that we’re on the right track, and you’ve got to have the focus and the vision to get you through the finish line.
Garraway: Yeah, Sam, I think it’s a really prescient question because I know that both Connie and Cathy are part of outstanding institutions where unfortunately, the waiting rooms are still all too full with patients, some of whom are benefiting from these approaches, but others are not benefiting enough, or even at all from these approaches. So the unmet need is still quite considerable, and sometimes it feels like the pace of advance, it’s almost like, there’s a concept of how evolution happens, which is punctuated equilibrium: There’s a bunch of evolution, and then it plateaus, and there’s a bunch more, and then it plateaus. Cancer research and drug development can be like that. So you have this flurry of activity that led to targeted therapies, and then you have this flurry of activity that established immunotherapies, but all the while, you can be in these plateau phases also, where it’s like, “Oh, it’s not happening fast enough.” But the fact that these advances have happened and that we’ve been fortunate enough in our careers to either witness or, in some cases, participate in those advances, it doesn’t get old. You don’t forget those moments of impact, those opportunities to bring the advances. That’s what motivates you to bring more of those. I know for me, that’s what wakes me up in the morning.
Lehman: I actually think our strongest energy is around what we know needs to be done and the technology we have to make that happen. So we need to have the right people agree that this is the direction we have to go in. You can be in those domains where dogma, and this is the way we’ve always done it, and politics, can slow down the implementation and the progress. And so that’s really in the domain that I’m working the most in. The early detection-prevention side is to change the guidelines, to change the approach, to change how we think about how we screen to detect breast cancer early.
COVID was such a horrible period for so many, but one of the silver linings was we realized that we can be both safe and fast in certain domains of healthcare. I had been struggling with how many barriers there were to telehealth and to providing services to women in rural areas and in healthcare deserts. All of a sudden, all those barriers with COVID, it’s like, we can probably do these things that we used to always say weren’t safe, weren’t OK. But now that we need to do it, we can do it. I think it gave people new vision in what can be accomplished. That is something that’s going to be exciting as we continue to move forward in the next few years.
Laine Perfas: Thank you for this wonderful conversation.
Thanks for listening. To find a transcript of this episode and links to all of our other episodes, visit harvard.edu/thinking. This episode was hosted and produced by me, Samantha Laine Perfas. It was edited by Ryan Mulcahy, Simona Covel, and Paul Makishima with additional editing and production support from Sarah Lamodi. Original music and sound designed by Noel Flatt. Produced by Harvard University, copyright 2024.
We ingest equivalent of credit card per week — how worried should we be? In ‘Harvard Thinking,’ experts discuss how to minimize exposure, possible solutions.
Science & Tech
Kempner AI cluster named one of world’s fastest ‘green’ supercomputers
The Kempner Institute AI cluster’s graphics processing units are networked together to allow for incredibly fast parallel processing. Credit: Harvard University
Yohan J. John
Harvard Correspondent
November 19, 2024
long read
Computational power can be used to train and run artificial neural networks, creates
Kempner AI cluster named one of world’s fastest ‘green’ supercomputers
The Kempner Institute AI cluster’s graphics processing units are networked together to allow for incredibly fast parallel processing.
Credit: Harvard University
Yohan J. John
Harvard Correspondent
long read
Computational power can be used to train and run artificial neural networks, creates key advances in understanding basis of intelligence in natural and artificial systems
Researchers at Harvard now have access to one of the fastest and greenest supercomputers in the world.
Built to support cutting-edge research at the Kempner Institute for the Study of Natural and Artificial Intelligence, and Harvard University more broadly, the Kempner’s AI cluster has just been named the 32nd fastest “green” supercomputer in the world in the Green500, the industry’s premier, independent ranking of the most energy-efficient supercomputers globally. In addition to cracking the top 50 list of green supercomputers, the cluster has been certified as the 85th fastest supercomputer overall in the TOP500, making it one of the fastest and greenest supercomputers on the planet.
“The Kempner AI cluster’s ranking in the latest Green500 and TOP500 lists positions us squarely among the fastest and most eco-friendly AI clusters in academia and the world,” said Max Shad, Kempner senior director of AI/ML research engineering. “It is no small feat to have built this kind of green high-performance computing power in such a short period of time, enabling cutting-edge research that is innovating in real time, and allowing for truly important advancements at the intersection of artificial intelligence and neuroscience.”
High-performance computing forms the backbone of the massive growth in the field of machine learning, and researchers at the Kempner Institute are leveraging this immense computational power to train and run artificial neural networks, leading to key advances in understanding the basis of intelligence in natural and artificial systems.
The Kempner Institute AI cluster is housed at the Massachusetts Green High Performance Computer Center in Holyoke, Massachusetts, and uses a variety of state-of-the-art techniques to minimize energy usage.
Credit: Harvard University
Measuring green compute power, from flops to gigaflops
The Kempner’s AI cluster opened with an initial pilot installation in spring 2023, and now represents the forefront of Harvard’s growing engagement with state-of-the-art computing resources. Composed of 528 specialized computer processors called graphics processing units (GPUs), which are networked together in parallel with “switches” to enable fast and simultaneous computation, the cluster can run rapid computations on hundreds of research projects at once.
To gauge the cluster’s green computing power and overall computing power, engineers from Lenovo measured the speed of the cluster’s highest-performing GPUs (called H100s) using the LINPACK Benchmark, which requires solving vast linear algebra problems. This is expressed in terms of floating point operations per second, or “flops.” The system’s efficiency, or “green” computing capacity, depends on how many flops the H100s can perform with a given amount of power, which is expressed as gigaflops per watt of power used.
The Kempner’s H100s demonstrated the capability to perform 16.29 petaflops, at an efficiency of 48.065 gigaflops per watt of power used.
Just how fast is the Kempner AI cluster? To get a sense of perspective on the Kempner’s 16.29 petaflops of computing power, consider this: The computers aboard Apollo 11, which took Neil Armstrong and Buzz Aldrin to the moon in 1969, were capable of 12,250 flops. That sounds like a lot, but by the 1980s much faster computations were possible: The CRAY-2 supercomputer recorded a performance of 1.9 gigaflops. That’s 1.9 billion flops. And now we have vastly more computing power in our pockets. The iPhone 15 is capable of more than 1,700 gigaflops. And the Kempner’s AI cluster has more than 16 petaflops of computing power — that’s 16 followed by 15 zeros — which is four orders of magnitude greater than the iPhone in your pocket. These numbers suggest that the ability of a Large Language Model (LLM) to produce grammatically correct language and simulate cognition is more computationally intensive than navigating a rocket to the moon — at least for now.
A supercomputer supporting new research at the Kempner, and across Harvard
With this magnitude of computing power, Kempner researchers are able to train state-of-the-art AI systems like large language models (LLMs), of which ChatGPT is perhaps the best known, quickly and efficiently. For example, the Kempner cluster can train the popular Meta Llama 3.1 8B and Meta Llama 3.1 70B language models in about one week and two months, respectively. Before the Kempner’s cluster was established and operational, training the Llama models on the next-fastest computer system at Harvard would have taken years to complete.
Beyond using the cluster to create faster models, researchers are also employing the cluster to better understand how and why they work. “With this enhanced computational power, we can delve deeper into how generative models learn to reason and complete tasks with greater efficiency,” says Kempner Institute Research Fellow Binxu Wang.
In addition to providing researchers with the capacity to train complex models quickly and efficiently, and to understand the mechanisms behind how they learn, the Kempner cluster enables scientists to compare vast numbers of model architectures and learning algorithms in parallel, with important applications in fields ranging from medicine to neuroscience. One example: In research recently published in Nature Medicine, Kempner associate faculty member and Harvard Medical School Assistant Professor Marinka Zitnik and colleagues used the cluster to develop and train TxGNN, an AI system that distills vast amounts of medical data into knowledge graphs, and then uses the graphs to predict the effectiveness of a drug for treating rare diseases.
The Kempner GPUs form part of Harvard University’s growing computational ecosystem, joining new or soon-to-be-available GPUs supported by Harvard’s Faculty of Arts and Sciences Research Computing (FASRC). More than 5,200 researchers across the University make use of these computing resources in a wide array of scientific and technological applications.
The power of parallel processing
So what exactly is a cluster? As the name suggests, a computing cluster gathers together multiple devices, each of which can function as a full-fledged computer in its own right. Linking devices together unleashes the power of parallel computing, which leads to massive speed-ups in processing time by performing large numbers of tasks simultaneously.
Until a few decades ago, most computers were powered by a central processing unit (CPU) that could only perform one computational operation at a time. By the early 2000s, computer scientists had figured out how to create “multicore” CPUs that perform multiple computations in parallel.
The road to supercomputing clusters like the Kempner’s involved stacking several levels of parallel processing on top of each other. After the introduction of multicore CPUs, the next level of parallelism was enabled by the use of GPUs. Controlling the graphics on a computer screen requires large numbers of very similar computations that can be done simultaneously. For example, displaying a video game requires computing the brightness and color of millions of pixels up to 120 times per second. GPUs perform these numerous yet simple computations in parallel, freeing up the CPU to perform more complex computations.
Computer scientists realized that the capacity of GPUs to perform vast numbers of parallel computations could be repurposed for other tasks, such as machine learning. Running an artificial neural network such as OpenAI’s GPT or DALL-E, for example, involves vast numbers of mathematical operations that can be performed in parallel. But the parallelism doesn’t stop here: Yet another level of parallelism is enabled by linking multiple GPUs together in a network. The Kempner’s network involves hundreds of NVIDIA GPUs — 144 A100s and 384 H100s — that can work in concert. This multilevel parallelism empowers the Kempner’s researchers to perform the dizzyingly intensive computations involved in the study of natural and artificial intelligence and to develop new AI applications in areas such as medicine.
When it comes to fast and flexible experimentation, iteration, and computationally intensive research, the Kempner AI cluster is, in the words of Boaz Barak, “absolutely instrumental.” Barak, a Kempner associate faculty member and professor at the Harvard John A. Paulson School of Engineering and Applied Sciences, says his lab group “relies on extensive computational experiments using the cluster” to study the mechanisms, capabilities, and limitations of deep learning systems. This, he says, allows his lab group to “hone intuitions and study questions as they arise.”
A powerful supercomputer, built to be green
Intentionally built for optimal energy consumption, the Kempner’s AI cluster is also setting a standard for “green” supercomputing. Modern machine learning has resulted in unprecedented advances in AI, but the methods are increasingly energy-intensive. Lowering the carbon footprint of AI is therefore crucial so that advances in AI do not come at the cost of exacerbating global warming.
Housed at the Massachusetts Green High Performance Computer Center (MGHPCC) along with other FASRC resources, and located in the town of Holyoke, Massachusetts, the Kempner’s AI cluster uses a variety of state-of-the-art techniques to minimize energy usage and make every megawatt of power count. The center is powered by the Holyoke municipal electric company, which delivers 100 percent carbon-free energy through a hydroelectric power station and several solar arrays that they operate.
As the central computing hub employed by most of the state’s research universities, including Harvard, MIT, UMass, Northeastern and Boston University, the MGHPCC was the first university research data center to achieve LEED Platinum Certification, the highest level awarded by the Green Building Council’s Leadership in Energy and Environmental Design Program. Moving forward, the Kempner’s partnership with MGHPCC will allow it to continue to grow with efficiency in mind, keeping the Kempner’s AI cluster green and efficient even as it grows into an even faster and more powerful tool for advancement in the field.
“Building an AI cluster that is not just blazing fast but also energy-efficient fits squarely into the Kempner’s mission, both to advance the field of intelligence, and to do so in a way that benefits people,” said Kempner Executive Director Elise Porter. “We have worked closely with MGHPCC to ensure this cluster is built with energy efficiency top of mind, and ranking as the 32nd fastest green supercomputer in the world is a testament to that work.”
Fast, green — and human
While landing a top spot on the TOP500/Green500 list is no small accomplishment, the real power of the Kempner’s work is knowing how to leverage its impressive computing resources to facilitate groundbreaking research. This involves more than building the AI cluster and giving researchers access to it. After all, researchers can’t just copy and paste old code into new machines — certain types of algorithms that work on traditional computers have to be reconceptualized and reformatted to be used with the Kempner’s computing infrastructure.
To this end, the Kempner has assembled a “full-stack” team of professional research engineers and research scientists with expertise ranging from distributed computing to data architecture to computational neuroscience. This Research & Engineering team develops codebases and standards, working with researchers to enable a seamless pipeline connecting scientific problems to computational solutions. The team also ensures that scientific findings are reproducible by helping students, fellows and faculty adopt industry-tested best practices for coding, testing, and maintenance of open repositories for models and data.
This human know-how is central to the ability of the Kempner community — and researchers all across Harvard University — to harness the scientific and technological potential of the green supercomputing power now available at its collective fingertips.
To find out more about the latest Kempner Institute research, check out the Deeper Learning blog.
Across history, Republican presidents rarely fell in line with what many today consider GOP economic orthodoxy, said economist Oren Cass.Photo by Beth Pezzoni
Work & Economy
How free-market policymakers got it all wrong for decades
Conservative economist says singular focus on deregulation, unfettered trade failed to deliver for American households
Christy DeSmith
Harvard Staff Writer
November 19, 2024
How free-market policymakers got it all wrong for decades
Conservative economist says singular focus on deregulation, unfettered trade failed to deliver for American households
Christy DeSmith
Harvard Staff Writer
6 min read
The free-market policymakers of the late 20th and early 21st centuries have “an empirical problem,” said Oren Cass, J.D. ’12, founder and chief economist of the conservative think tank American Compass.
“The stuff they were doing on economics did not work.”
Cass’ ideas, anchored by social conservatism, are gaining traction with a younger set of policymakers on the right. But his pro-worker rhetoric overlaps at times with language used on the left. “Marco Rubio and J.D. Vance on one side and Bernie Sanders and Elizabeth Warren on the other actually see a lot of the same problems in the economy and are willing to say it,” offered Cass, who rang a note of optimism over this “increasing consensus.”
Across U.S. history, he said, Republican presidents rarely fell in line with what many today consider GOP economic orthodoxy. Abraham Lincoln, William McKinley, Teddy Roosevelt Jr., and Richard Nixon all used tariffs to shore up domestic industry and protect the country’s wage earners.
Former President Ronald Reagan, celebrated by conservatives for his embrace of free enterprise, raised taxes at least five times and was far more protectionist than his reputation might suggest. Cass underscored this point by offering background on Reagan’s famous quote: “I’ve always felt the nine most terrifying words in the English language are: I’m from the government, and I’m here to help.”
Reagan uttered these words in 1986 while announcing record-breaking aid to American farmers, including drought assistance and price supports. “One of the very funny things about what we think of as Reaganomics, conservative economics — what I call market fundamentalism — is it’s actually a post-Reagan phenomenon,” Cass said.
How did the market fundamentalism come to dominate politics on the right? Cass, a policy adviser to Mitt Romney’s 2012 presidential campaign, pointed to the distinct interest groups that comprised the famous “three-legged stool” of Reagan’s electoral coalition: social conservatives, economic libertarians, and national security hawks.
“What do these three groups have in common?” Cass asked. “They all really, really, really hate communists. And in the middle of the Cold War, in the context where the Democratic Party was — let’s be honest — a little squishy on communism, getting together everybody who really, really, really hated communism turned out to be a powerful strategy.”
This coalition collapsed in 1989 with the Berlin Wall, Cass continued. That left the three-legged stool in splinters, with each faction vying for supremacy. “That is the economic libertarians unchained from any actual Cold War just running amok,” he argued. “This is [activist] Grover Norquist getting everybody to agree they will never raise taxes under any circumstances.
“And by the time you get to the 2000s, you have a bunch of [President George W.] Bush tax cuts that bear no relationship to any economic priority and manage to send us back into debt while producing no economic growth whatsoever. You have several massive new wars starting to no apparent effect. And you have social conservatives sort of sitting there, losing on their priorities for the most part.”
For 30 years, that group ceded all territory on economic issues, Cass said. “And then they started to say, ‘Wait a minute. The economy that the economic libertarians are producing does not align with any of the things we actually believe equate to human flourishing.’”
Core to Cass’ critique is the economic libertarian focus on cheap consumer goods over building a labor force where workers can support strong families.
As evidence that the free-market era has failed to deliver for the average American household, Cass showed a series of charts detailing everything from the growing U.S. trade deficit to 50 years of stagnant wage growth even amid rising per-capita GDP. Over the same period, deregulation led to the rise of offshoring, while an increasingly dominant financial sector embraced high-speed trading and speculation over investments in U.S. communities.
Cass also shared a data visualization of America’s growing reliance on government transfers, recently published by a bipartisan Economic Innovation Group associated with Facebook founding president Sean Parker. The display can be read as a “massive victory” by free-market thinkers focused, above all, on individual purchasing power, Cass argued.
But he ventured that most Americans are unsettled by increased dependence on Social Security, veterans’ benefits, and other federal aid programs. “This is not actually a sustainable model for a thriving nation either socially or economically,” he said.
“This is not actually a sustainable model for a thriving nation either socially or economically.”
Oren Cass
Conservatives like to approach the market in definitional terms, Cass explained. What is the market, and what is it for? He rejected the terms put forth by former U.S. Senator Pat Toomey during a 2020 talk at the Heritage Foundation.“The market is … really just the name that we assign to the sum total of all the voluntary exchanges that occur every day by free men and women,” Toomey said.
“That’s not a market,” Cass countered. “A market is a much more complex mechanism that allocates labor and capital in response to conditions, rules, and institutions.”
What is the market actually for, in his view? “It’s not just for optimizing consumption,” Cass said. “We need to do a lot more than that, because we don’t want to rely on government to do everything else. We need it to empower workers to support their families. We need it to strengthen the social fabric. We need it to foster domestic investment and innovation.
“And if that’s the case, the role for policymakers isn’t as little as possible,” he concluded. “Their role is to create the rules and support the institutions that will lead to productive applications.”
Science & Tech
How humans evolved to be ‘energetically unique’
Andrew Yegian and Daniel Lieberman.Photo by Dylan Goodman
Anne J. Manning
Harvard Staff Writer
November 18, 2024
4 min read
Metabolic rates outpaced ‘couch potato’ primates thanks to sweat, says new study
Humans, it turns out, possess much higher metabolic rates than other mammals, including our close relatives, apes and
Metabolic rates outpaced ‘couch potato’ primates thanks to sweat, says new study
Humans, it turns out, possess much higher metabolic rates than other mammals, including our close relatives, apes and chimpanzees, finds a new Harvard study. Having both high resting and active metabolism, researchers say, enabled our hunter-gatherer ancestors to get all the food they needed while also growing bigger brains, living longer, and increasing their rates of reproduction.
“Humans are off-the-charts different from any creature that we know of so far in terms of how we use energy,” said study co-author and paleoanthropologist Daniel Lieberman, the Edwin M. Lerner Professor of Biological Sciences in the Department of Human Evolutionary Biology.
The paper, published Monday in Proceedings of the National Academy of Sciences, challenges a previous consensus that human and non-human primates’ metabolic rates are either the same or lower than would be expected for their body size.
Comparisons of resting, active, and total metabolic quotients among various species and human populations, as defined by the Harvard researchers’ new method.
Credit: Andrew Yegian
Using a new comparison method that they say better corrects for body size, environmental temperature, and body fat, the researchers found that humans, unlike most mammals including other primates, have evolved to escape a tradeoff between resting and active metabolic rates.
Animals take in calories through food and, like a bank account, spend them on expenses mostly divided between two broad metabolic categories: resting and physical activity. In other primates, there is a distinct tradeoff between resting and active metabolic rates, which helps explain why chimpanzees, with their large brains, costly reproductive strategies, and lifespans, and thus high resting metabolisms, are “couch potatoes” who spend much of their day eating, said Lieberman.
Generally, the energy animals spend on metabolism ends up as heat, which is hard to dissipate in warm environments. Because of this tradeoff, animals such as chimpanzees who spend a great deal of energy on their resting metabolism and also inhabit warm, tropical environments, have to have low activity levels.
“Humans have increased not only our resting metabolisms beyond what even chimpanzees and monkeys have, but — thanks to our unique ability to dump heat by sweating — we’ve also been able to increase our physical activity levels without lowering our resting metabolic rates,” said co-author Andrew Yegian, a senior researcher in Lieberman’s lab.
“The result is that we are an energetically unique species.”
“Humans have increased not only our resting metabolisms beyond what even chimpanzees and monkeys have, but — thanks to our unique ability to dump heat by sweating — we’ve also been able to increase our physical activity levels without lowering our resting metabolic rates.”
Andrew Yegian
The team’s analysis shows that monkeys and apes evolved to invest about 30 to 50 percent more calories in their resting metabolic rates than other mammals of the same size, and that humans have taken this to a further extreme, investing 60 percent more calories than similar-sized mammals.
“We started off questioning if it was possible that humans and other primates could have comparatively low total metabolic rates, which other researchers had proposed,” Yegian said. “We tried to come up with a better way to analyze it using quotients. That’s when we hit the accelerator.”
The research team — which includes collaborators at Louisiana’s Pennington Biomedical Research Center and the University of Kiel in Germany — plans to further investigate metabolic differences among human populations. For example, subsistence farmers who grow all the food they eat without the help of machines have significantly higher physical activity levels than both hunter-gatherers and people in industrial environments like Americans. However, all human populations, regardless of activity levels, spend similar amounts of energy for their body size on their resting metabolic rates.
“What we’re really interested in is variation among humans in metabolic rates, especially in today’s world of increasing technology and lower levels of physical activity,” said Yegian. “Since we evolved to be active, how does having a desk job change our metabolism in ways that affect health?”
Host Meira Levinson (clockwise from top left), Carlton Green, Richard Weissbourd, and Kara Pranikoff.Stephanie Mitchell/Harvard Staff Photographer
Nation & World
Seeing schools as ‘laboratories of democracy’
Encounters with different perspectives are a key part of the learning experience, panelists say
Liz Mineo
Harvard Staff Writer
November 18, 2024
3 min read
An Ed School panel high
Encounters with different perspectives are a key part of the learning experience, panelists say
Liz Mineo
Harvard Staff Writer
3 min read
An Ed School panel highlighted the critical role schools can play in helping students learn to listen to different perspectives and have conversations across divides in a webinar on Thursday.
“Schools are one of the places where people with diverse perspectives are often together,” said Richard Weissbourd, senior lecturer on education. “Other settings are often not diverse, or at least they’re contained or bounded in ways that schools are not … Schools can be laboratories of democracy.”
Led by Meira Levinson, Juliana W. and William Foss Thompson Professor of Education and Society, the panel made the case for schools as ideal settings for lessons in compromise and civil disagreement.
“Schools are socializing agents,” said Carlton Green, an assistant clinical professor and co-director of Intergroup Dialogue Training Center at the University of Maryland. “That is where we learn some of the ethic around how to be in community with other people, especially people who are different from us.”
Educators help students learn interpersonal skills and how to navigate conflict, the panelists noted, fostering their social and emotional development. Although that work has been part of education for decades, the concept of “social-emotional learning” has recently come under attack by some conservative activists — and parents — who insist that teachers should focus strictly on academic learning.
Kara Pranikoff, an education consultant and coach, pushed back on that idea.
“We have this tendency to say that social-emotional learning is one thing, and academic learning is another thing,” said Pranikoff. “But we cannot separate our social-emotional selves from our academic selves. It’s just not possible, even if people report that it is. It’s not part of being a human. They go hand in hand.”
As microcosms of society, schools experience their own versions of national debates over issues such as religion, LGBTQ rights, and immigration, creating third-rail moments for teachers, the panelists said.
“There are things that you can say that are going to trigger a parent,” Weissbourd said. “Without support from your administration, these conversations become very difficult.”
But those conversations are important, said Weissbourd, who directs the Ed School program Making Caring Common, which provides resources for families and educators to help children develop empathy and other emotional capacities.
“It’s important to be able to mend fractures and for people to get along,” said Weissbourd. “But we want to have these conversations because we really believe in principles of human rights, justice, inclusion, and fairness. Part of the work, too, is how do you have conversations in ways that advance those principles?”
Educators should rise to their daily challenges by communicating with parents and building support from school administrators, Green said.
“I’d say to parents, ‘I think you want me to help your child be a good human, right?’ and if you have questions about me helping your child to be a good human in the context of the other little humans, I’m open to that, but that’s what I’m committed to doing,” said Green. “We are educating good humans here.”
Health
Too much sitting hurts the heart
Even with exercise, sedentary behavior can increase risk of heart failure by up to 60%, according to study
MGB Communications
November 18, 2024
4 min read
A new study shows that being sedentary increases the risk of the most common types of heart disease, even among those who get enough exercise.
Investigators at Mass General Brigham found sedentary behav
Even with exercise, sedentary behavior can increase risk of heart failure by up to 60%, according to study
MGB Communications
4 min read
A new study shows that being sedentary increases the risk of the most common types of heart disease, even among those who get enough exercise.
Investigators at Mass General Brigham found sedentary behavior was associated with higher risks of all four types of heart disease, with a marked 40-60 percent greater risk of heart failure and cardiovascular death when sedentary behavior exceeded 10.6 hours a day. (Sedentary behavior is defined as waking activity with low energy expenditure while sitting, reclining, or lying down and does not include hours spent sleeping at night.)
Researchers also emphasized that meeting guideline levels of moderate-to-vigorous physical activity may be insufficient on its own to reduce cardiovascular risk if one is also sitting too much.
“Many of us spend the majority of our waking day sitting, and while there’s a lot of research supporting the importance of physical activity, we knew relatively little about the potential consequences of sitting too much beyond a vague awareness that it might be harmful,” said lead author Ezimamaka Ajufo, a cardiology fellow at Brigham and Women’s Hospital.
“Sedentary risk remained even in people who were physically active, which is important because many of us sit a lot and think that if we can get out at the end of the day and do some exercise we can counterbalance it,” Ajufo says. “However, we found it to be more complex than that.”
Ajufo’s team, which included researchers from across MGB, analyzed one week of activity-tracker data from 89,530 individuals from the U.K. Biobank prospective cohort.
They looked at associations between daily time spent sitting and the future risk of four common cardiovascular diseases: atrial fibrillation, heart attacks, heart failure, and death from cardiovascular causes. The team used a machine learning algorithm to classify sedentary behavior.
Many of the negative effects of sedentary behavior persisted even among those individuals who achieved the guideline-recommended more than 150 minutes of moderate-to-vigorous physical activity per week.
For example, although the study found that the risk of atrial fibrillation and heart attacks could be mostly eliminated by engaging in physical activity, the excess risk of heart failure and cardiovascular death could only be partially offset by physical activity.
“Our data supports the idea that it is always better to sit less and move more to reduce heart disease risk, and that avoiding excessive sitting is especially important for lowering risk of heart failure and cardiovascular death,” said co-senior author Shaan Khurshid, an electrophysiologist and faculty member in the Telemachus And Irene Demoulas Family Foundation Center for Cardiac Arrythmias at Massachusetts General Hospital.
The research team hopes these findings will help inform future guidelines and public health efforts. They would like future prospective studies to test the efficacy of public health interventions that help people reduce the number of hours they spend being sedentary and see how that affects cardiovascular health.
Next, they plan to extend this research to investigate the impacts of sedentary behavior on a range of other diseases and for longer spans of time.
“Exercise is critical, but avoiding excessive sitting appears separately important,” said co-senior author Patrick Ellinor, a cardiologist and co-director of the Corrigan Minehan Heart Center at Massachusetts General Hospital. “Our hope is that this work can empower patients and providers by offering another way to leverage movement behaviors to improve cardiovascular health.”
Authorship: Additional Mass General Brigham authors include Timothy W. Churchill, J. Sawalla Guseh, and Krishna G. Aragam. Additional authors include Shinwan Kany and Joel T. Rämö.
Disclosures: Krishna G. Aragam receives sponsored research support from Sarepta Therapeutics and Bayer AG; he also reports a research collaboration with the Novartis Institutes for Biomedical Research. Patrick T. Ellinor receives sponsored research support from Bayer AG, IBM Research, Bristol Myers Squibb, Pfizer and Novo Nordisk; he has also served on advisory boards and/or consulted for Bayer AG.
Researchers were supported by the John S. LaDue Memorial Fellowship in Cardiovascular Medicine or Vascular Biology grant, the Walter Benjamin Fellowship from the Deutsche Forschungsgemeinschaft (521832260), a research fellowship from the Sigrid Jusélius Foundation, the National Institutes of Health (K23HL159262-01A1, 1K08HL153937, RO1HL092577, R01HL157635, and K23HL169839-01), the American Heart Association (19AMFDP34990046, 862032, 18SFRN34230127, 961045, and 2023CDA1050571), the President and Fellows of Harvard College (5KL2TR002542-04), and the European Union (MAESTRIA 965286).
Getty Images
Campus & Community
8 Harvard students named Rhodes Scholars
5 in U.S. class, most for any institution, joined by 3 international recipients
FAS Communications
November 17, 2024
4 min read
Five Harvard College students are among the 32 U.S. Rhodes Scholars for 2025, the most awarded to any institution this year. Three international students in the College also received Rhodes Schola
5 in U.S. class, most for any institution, joined by 3 international recipients
FAS Communications
4 min read
Five Harvard College students are among the 32 U.S. Rhodes Scholars for 2025, the most awarded to any institution this year. Three international students in the College also received Rhodes Scholarships, bringing Harvard’s total to eight.
The students will attend Oxford University next year to pursue graduate studies in fields ranging from political theory to neuroscience.
Harvard’s 2025 Rhodes Scholars:
Matthew Anzarouth of Quebec, Canada, was awarded a Rhodes Scholarship for Canada. A former competitive debater, Anzarouth won the World Schools Debating Championship with Team Canada in 2020 and 2021, and competed for the Harvard College Debating Union in his first year at the University. During his time at Harvard, where he concentrated in social studies, he served as senior world editor at the Harvard Political Review, co-founded and co-hosted a podcast exploring political and philosophical issues, and coached debate for high school students. Combining his interests in political theory and Canadian politics, Anzarouth is writing his senior thesis on Canadian federalism and multiculturalism. He plans to study political theory at Oxford.
Lena R. Ashooh of Shelburne, Vermont, designed a major in animal studies, with research in philosophy, psychology, biology, political science, and other disciplines. She has worked with land law examiners as an intern at the U.S. Bureau of Land Management and has lobbied legislators as an environmental justice intern at the Center on Race, Poverty, and the Environment, a California nonprofit. Ashooh conducted field research on macaque monkeys in Puerto Rico, plays classical harp, and has created a stop-motion animation film about the ethics of eating animals. She plans to study political theory at Oxford.
Shahmir Aziz of Lahore, Pakistan, was named one of two Rhodes Scholars for Pakistan last month. He has conducted research in drug delivery and bio-nanotechnology. Outside the classroom, he is passionate about diplomacy and global governance, serving as a leader of the Harvard International Relations Council and Harvard’s Model UN Team. Aziz plans to continue researching bio-nanotechnology at Oxford while also studying diplomacy with a focus on global health to better understand how to cultivate cross-border ideas in biotech.
Thomas Barone of Little Falls, New Jersey, is a social studies concentrator focused on intellectual history, political rhetoric, and policy. He has interned at the national politics desk of ABC News and serves as editorial chair of The Harvard Crimson, where he won first place for editorial writing in collegiate journalism in the Society of Professional Journalists’ Mark of Excellence Awards. Barone intends to study history at Oxford and plans to pursue a career in journalism.
Sofia L. Corona of Delray Beach, Florida, is studying applied mathematics and economics. She designed her course of study to develop a multidisciplinary perspective on issues in transportation policy, including infrastructure development, clean energy governance, and community decision-making. She worked on federal transportation oversight cases as a legal intern at the U.S. Department of Transportation; researched community participation and renewable energy implementation at the Allen Lab for Democracy Renovation in Harvard Kennedy School’s Ash Center for Democratic Governance and Innovation; and analyzed alternative vehicle upgrades for car models at BMW. She has climbed Aconcagua, Denali, and Mount Kilimanjaro. At Oxford, Corona plans to pursue economics and focus on development, sustainability, and enterprise.
Aneesh Muppidi of Schenectady, New York, is a concentrator in computer science and neuroscience. He has conducted research at the Computational Robotics Lab and the Computational Cognitive Neuroscience Lab, both at Harvard, and MIT’s Fiete Lab, and has been involved in AI policy discussions for New York State and the federal government. Muppidi served as president of the Harvard Computational Neuroscience Undergraduate Society, co-president of the Hindu Students Association, and president of the Harvard Spikeball Club. At Oxford, he will study advanced computer science and public policy.
Ayush Noori of Bellevue, Washington, is studying computer science and neuroscience. His research uses artificial intelligence to comb large-scale biomedical data for diagnosis and treatment options, and he has developed an AI model that can be deployed to predict treatment outcomes in bipolar disorder, Parkinson’s disease, and neuropathic conditions. He has co-authored more than 20 peer-reviewed papers and was awarded the Barry Goldwater Scholarship for natural sciences. Noori is co-founder and co-president of the Harvard Undergraduate OpenBio Laboratory. At Oxford, he hopes to complete degrees in clinical neurosciences and in physiology, anatomy, and genetics.
Laura Wegner of Walsrode, Germany, was one of two recipients of German Rhodes Scholarships. She studies economics and computer science and founded Mii, a digital healthcare passport that empowers patients to manage and access their health records anywhere in the world. At Oxford, Wegner plans to pursue graduate work focused on digital health care technology.
Read more about this year’s Rhodes Scholars at the Rhodes Trust.
Lawrence Summers (right) talks with journalist John Ellis at Harvard Kennedy School.Photo by Martha Stewart
Nation & World
Summers says Trump’s plans could damage economy
Professor and former Treasury secretary discusses why Democrats lost election, need for more patriotism
Christina Pazzanese
Harvard Staff Writer
November 15, 2024
5 min read
Democrats lost the 2024 election because t
Professor and former Treasury secretary discusses why Democrats lost election, need for more patriotism
Christina Pazzanese
Harvard Staff Writer
5 min read
Democrats lost the 2024 election because they paid too much attention to positive macroeconomic trendlines and not enough to Americans’ economic reality, according to economist Larry Summers.
“In too many ways, Democrats have lost sight of the common man and woman in favor of the attitudes and philosophies of the faculty common room,” said Summers during a talk Thursday night on why the Democrats lost the 2024 election and the risks President-elect Donald Trump’s policy plans pose for the U.S. economy.
Many voters moved toward the Republican Party and Trump, who hammered Democrats over inflation, because they felt the GOP understood what they were going through better than Democrats, who strayed from their traditional focus on issues like kitchen-table economics, said Summers, who was Treasury secretary during the Clinton administration and is currently the Charles W. Eliot University Professor and the Frank and Denie Weil Director of the Mossavar-Rahmani Center for Business and Government at the Harvard Kennedy School.
The Federal Reserve also contributed to voters’ anger over inflation, he suggested.
In 2021, when $2.5 trillion in stimulus funding was flooding the economy, the Fed was still anticipating interest rates would stay at 0 percent through summer 2024 and buying back long-term Treasury debt by issuing “what was, in effect, floating-rate short-term debt.” This led to significant losses to the government that some estimate — in market value terms — at $500 billion to $1 trillion, before the Fed finally course-corrected, said Summers, who also served as director of National Economic Council during the Obama administration.
“I think that if there had not been hyper-expansionary policy in 2021, it would have been easier for Democrats to escape blame for whatever inflation took place,” he said.
Summers worries the Fed could err once again during the new administration given current economic conditions, and he warned Trump’s economic policy plans, such as raising or adding new tariffs, could worsen inflation.
“If President Trump does what he said he would do during his campaign, the inflation shock administered to the economy is substantially larger than anything that happened at the beginning of the last administration,” Summers said.
“He’s vowed huge deficit increases through continuation of his tax cuts and new tax cuts; he has trashed the idea of the independence of the central bank; he said that we should want to have a less highly valued currency, which means less valuable money [and] higher prices, and that’s just on the demand side,” he said.
More importantly, “He’s talked about a big tariff on every good that we import, which means higher import prices [and] also means higher prices for everything that competes with imports,” Summers said.
Summers criticized Trump’s promise to implement 60 percent tariffs on all Chinese goods, saying it will not only force American consumers to pay much higher prices, but will further strain U.S.-China relations. The U.S. ought to precisely “calibrate” its trade policies to the nation’s overall strategic objectives, he said.
“At a time when the Chinese economy is struggling, when there are very difficult economic problems, the worst thing we could do would be to make it completely easy for the Chinese government to scapegoat us for their own economic failings. And so, we need to be very careful that we are focused on our own security [and] … not pursue policies that can be interpreted as reflecting a generalized desire to suppress the Chinese economy,” he said, adding “That’s going to require subtle choices about policy and it’s going to require not bluster, but very careful communication.”
In addition, tightening U.S. borders is “clearly something we have to do,” he noted. “But if you’re talking about sending millions of people out of the country who are here now, that’s a prescription for large-scale labor shortages, and we’ve seen in the past what that does to inflation.”
Vice President Kamala Harris made a pitch to voters who “love our country,” a sentiment Summers said he’d like to see the Democratic Party and institutions like Harvard champion.
“I’d frankly like to see it as a value embraced more in our University, where it’s not something we talk about or celebrate or think about,” he said. “There’s plenty that we have done wrong in our history. But there’s something odd about the degree to which the history that is received in our educational system is as negative about our country as it is.”
The University needs to “find a way” to encourage patriotism as a positive principle on campus because the U.S. today faces “real threats” and because it is “an alternative to each subgroup of Americans embracing a particular identity, which leads to a great deal of divisiveness.”
Nation & World
What’s ahead for U.S. foreign policy in ‘Trump 2.0’?
Peter Baker and Susan Glasser. Photo by Grace DuVal
Christina Pazzanese
Harvard Staff Writer
November 15, 2024
4 min read
Peter Baker and Susan Glasser predict push to end Ukraine war on Russia’s terms, instability for NATO
President-elect Donald Trump is moving swiftly to announce Cabinet and other appointments for
What’s ahead for U.S. foreign policy in ‘Trump 2.0’?
Peter Baker and Susan Glasser.
Photo by Grace DuVal
Christina Pazzanese
Harvard Staff Writer
4 min read
Peter Baker and Susan Glasser predict push to end Ukraine war on Russia’s terms, instability for NATO
President-elect Donald Trump is moving swiftly to announce Cabinet and other appointments for a second term in office, which many observers expect to pick up where he left off in January 2021 on major policy issues like immigration, trade, and foreign relations.
What will be different, say veteran Washington journalists Susan Glasser ’90, and Peter Baker, is the speed at which Trump will move to advance his agenda, with a likely boost from a Republican majority in Congress.
“Trump 2.0 is Trump on steroids,” Baker, senior White House correspondent at The New York Times, told moderator Yevgenia Albats, Ph.D. ’04, a Russian journalist and political scientist. The discussion on Tuesday with Baker and Glasser, a staff writer for The New Yorker, examined what U.S. policy with Russia, China, and the European Union may look like during a second Trump administration.
The pair, who are married, served in Moscow as co-bureau chiefs for The Washington Post from 2001 to 2004, and have written several books together, including “Kremlin Rising: Vladimir Putin’s Russia and the End of Revolution” in 2005 and “The Divider: Trump in the White House 2017-2021” in 2022.
Unlike in 2016, when he ran as a celebrity businessman who wanted to shake up Washington, Trump will return to the White House in January having run on “an explicit campaign of revenge and retribution,” according to Glasser, and intending to take care of what he sees as “unfinished business,” namely to “fundamentally reorient” U.S. foreign policy to his own more isolationist view of the country’s role in the world.
Trump has more experience now in how to use the levers of presidential power. And his loyalist picks for secretaries of state and defense and national security adviser — Sen. Marco Rubio, Army veteran and Fox TV host Pete Hegseth, M.P.P. ’13, and Rep. Mike Waltz — lack deep experience in foreign policy and will likely do little to restrain Trump’s plans, unlike their counterparts in Trump’s first term, they said.
“If you look [at] who’s in the room making decisions right now, there is no dissent,” Baker noted.
The fate of Ukraine is likely to be among the first matters Trump takes up.
The incoming president, who has reportedly engaged in back-channel talks with Putin, made a campaign promise to end the Ukraine war quickly. He is almost certain to cut off U.S. aid to Ukraine and try to broker a deal that will favor Russia, the pair told Albats, editor in chief of The New Times, an independent Russian language news outlet, and a visiting scholar at the Davis Center for Russian and Eurasian Studies at Harvard.
NATO’s fate in a second Trump term is unclear. As the president-elect demonstrated in his first term, “He has no interest and no commitment whatsoever to defend, frankly, anybody, but especially the Eastern European countries,” said Baker.
Even without a formal withdrawal by the U.S., as Trump repeatedly threatened during his first term, NATO is already weaker than it was before Nov. 5, he said.
“If you’re an adversary of NATO, Article 5 [which calls for the nations to defend one another if attacked] is meaningless, because if it’s a conditional thing, depending on the mood of the president of the United States as opposed to a solid commitment, it’s a dead letter,” said Baker.
“He has, just by getting elected, undercut NATO in a way that it has not been undercut” since its beginnings after World War II amid concerns over the rise of the Soviet Union as a nuclear power, he said.
Arts & Culture
The very model of a modern major initiative
On the nights they attend A.R.T. performances, Lavine Learning Lab students welcome audiences to the Loeb Drama Center.Photo by Lauren Miller
November 15, 2024
5 min read
A.R.T. and Lavine Learning Lab aim to create a space for intergenerational dialogue, deepen student engagement with theater
Supporting student engagement in live theater as
On the nights they attend A.R.T. performances, Lavine Learning Lab students welcome audiences to the Loeb Drama Center.
Photo by Lauren Miller
5 min read
A.R.T. and Lavine Learning Lab aim to create a space for intergenerational dialogue, deepen student engagement with theater
Supporting student engagement in live theater as it fosters lasting relationships between the two is the idea behind the American Repertory Theater’s Lavine Learning Lab. The new student initiative will, among other exercises, bring participating public high school students to an evening performance of every show in the company’s season.
Rooted in A.R.T.’s core values of inquiry and collaboration, the Lavine Learning Lab uses A.R.T. productions as the foundation for student workshops that bridge the arts, humanities, and social and emotional learning, fostering lasting relationships between the theater and its young audience.
“The theater is where we develop our muscles for inquiry, empathy, and debate,” said Artistic Director Diane Paulus ’88. “The Lavine Learning Lab will be a gymnasium where high school students will come to exercise their humanity so they can become the most impactful citizens and participants in our society.”
“The lab’s students will diversify A.R.T.’s audience in multiple dimensions, turning our theater into a space for intergenerational dialogue among people with different lived experiences and perspectives.”
Dayron J. Miles, A.R.T. associate artistic director
For each production, students participate in an introductory in-school workshop centered around the production’s “Essential Questions”; a pre-show workshop at A.R.T., held alongside a second Learning Lab school, exploring one of the production’s themes or elements, followed by dinner and a performance; and a post-show, in-school student-led workshop for students to unpack their own perspectives and those of others.
In addition, two educators from each participating school join a Professional Learning Community in which A.R.T. facilitates ongoing collaborative learning and provides professional development.
An important aspect of the program is Learning Lab students will attend evening performances of every show in A.R.T.’s season — instead of morning matinees traditionally designated for school groups. Students will sit in groups of two to four, alongside the general evening audience.
Students at a pre-show workshop with “Romeo and Juliet” actor Alex Ross.
Credit: A Priori Photography
“When we attend a performance, we aren’t impacted only by what we see onstage, but also by our fellow audience members,” said A.R.T. Associate Artistic Director Dayron J. Miles. “The lab’s students will diversify A.R.T.’s audience in multiple dimensions, turning our theater into a space for intergenerational dialogue among people with different lived experiences and perspectives. Empathy is a necessary tool for responsible democratic participation, and that’s what we can cultivate with this model.”
Evening attendance also builds familiarity with theatergoing and sense of belonging at the theater to cultivate a culture of lifelong theatergoing. To increase accessibility by removing common barriers, A.R.T. provides transportation between the schools and the theater and a pre-show dinner onsite.
The Lavine Learning Lab is supported by a $5 million gift from the Crimson Lion / Lavine Family Foundation, which was founded by Bain Capital Chair Jonathan Lavine, M.B.A. ’92, and Jeannie Lavine ’88, M.B.A. ’92, to support nonprofit organizations focused on leveling the playing field for individuals and families.
“We’ve been struck by A.R.T.’s commitment to expanding access to theater,” said Jeannie and Jonathan Lavine in a statement. “We are delighted to play a part in engaging Boston’s students and teachers in the essential questions sparked by A.R.T.’s world-class programming and in supporting A.R.T., whose work inspires people all throughout our city and this country.”
The Learning Lab exemplifies the type of community-centered, accessible programming A.R.T. will offer from its new home, the David E. and Stacey L. Goel Center for Creativity & Performance. Currently under construction at 175 N. Harvard St. in the Allston neighborhood of Boston, the center is expected to be completed in the fall of 2026.
A.R.T. facilitated a pilot with six public high schools during the 2023-2024 school year to develop the current model.
“I feel like a lot of my analytical skills have been reinforced and retaught in the Learning Lab, but I’ve also taken the vulnerability that I feel when I’m in the lab and applied it to other parts of my life,” said Malden High School student and pilot and Learning Lab participant Addison McWayne. “This experience has provided me with opportunities to speak up for myself and to share my opinion, which has made me a stronger and more confident person.”
“The lab is one of the ways that A.R.T. shares the resources of Harvard University with our community, but the A.R.T. community gains so much, too,” said Kelvin Dinkins Jr., executive director of the A.R.T. “The students bring their anticipation and excitement, which translates into a galvanizing energy on the sidewalk, in our lobbies, and in the theater itself that enhances the experience for everyone. Thanks to this incredible support from the Crimson Lion / Lavine Family Foundation, A.R.T. is positioned to bring our mission into public high schools across Boston for years to come.”
“When the Lavine Learning Lab works in Boston, we hope it will be a model for other cities, because A.R.T. has led the way in so many areas, and A.R.T. can help lead the way in providing this kind of access and inspiration to students all over the country,” said the Lavines.
Health
Is cheese bad for you?
Nutritionist explains why you’re probably eating way too much
November 14, 2024
3 min read
Part of the
Wondering
series
A series of random questions answered by Harvard experts.
The average American consumes 41.8 pounds of cheese per year. We asked Harvard Chan School nutritionist Walter C. Willett about the health i
A series of random questions answered by Harvard experts.
The average American consumes 41.8 pounds of cheese per year. We asked Harvard Chan School nutritionist Walter C. Willett about the health impact.
Whether cheese is good or bad for health depends on the comparison. It is somewhere in the middle of the spectrum from great (nuts and soy foods) to processed red meat. Like other dairy foods, cheese does have nutritional value, including a high calcium content. However, our calcium recommendations are seriously overstated because they are based on studies of several weeks, which is far too short.
Current National Institutes of Health recommendations suggest Americans older than 18 get 1,000 mg of calcium daily. However, as little as 600 mg is probably enough for most people.
Of course, the amount of cheese makes an important difference, and it has become common to put a huge amount in sandwiches and salads. About one serving of dairy foods a day is probably a good target; some evidence suggests that yogurt has some health advantages, and cheese could be part of that mix. But if you are thinking of a cheese sandwich, consider peanut butter on whole grain bread as an alternative, or adding nuts to your salad instead of cheese.
Like other dairy foods, cheese does have nutritional value, including a high calcium content. However, our calcium recommendations are seriously overstated.
Americans consume about 1.5 servings of dairy foods per day, and the majority of this is now in the form of cheese. This is a major shift over the last several decades; the total amount of dairy foods consumed has not changed greatly, but until recently this was mainly milk. The USDA has been strongly supporting consumption of cheese (despite their own guidelines encouraging reduction in saturated fat), which has probably contributed to this trend.
Some of the increases in cheese consumption are probably due to more people reducing red meat for various reasons including health, animal welfare, and climate change, but the strong promotion of cheese by the USDA has very likely been an important factor. Starting with the Dairy Production Stabilization Act of 1983, a small tax on sales of dairy has gone to the USDA to promote sales of dairy foods, creating a massive conflict of interest within the organization.
In the past, the vast majority of cheese consumed by Americans was cheddar, but we now consume a wider variety. There is no good evidence that one type or another is different for health.
The differences in nutrient content of cheeses are primarily due to the amount of water. Cottage cheese and other fresh cheeses with high water content have higher percentages of lactose — a carbohydrate that decreases with aging. As cheese ages and becomes hard like parmesan or manchego, the lactose is fermented and lost.
However, volume matters. We usually eat more cottage cheese than an aged cheese, so the amount of calories, calcium, and saturated fat can end up not being very different.
In addition to the direct effects of cheese on health, it is important to consider the implications for climate change because dairy production has a large impact on greenhouse gas emissions and land use. In an analysis conducted as part of the EAT-Lancet Commission on healthy and sustainable food systems, we found that if global production of dairy foods increased to 2 servings per day, limiting severe climate change would be difficult.